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1 intly contribute to a local 'gene expression factory'.
2 nt from, appropriate transcription sites or 'factories'.
3 ve genes to congregate in discrete 'NFkappaB factories'.
4 aryotic model and widely used microbial cell factory.
5 reventing formation of the viral replication factory.
6 in a VLS functioning as a virus replication factory.
7 organized for processing at each replication factory.
8 gregation and trapping of virions within the factory.
9 ong enough to allow re-initiation in another factory.
10 e enough to be present on the surface of one factory.
11 and one Pol alpha-primase into a replication factory.
12 matin domain (TID) functioning as a splicing factory.
13 mounts of O-glycans as a potential O-glycome factory.
14 entiated rhizobia effectively become ammonia factories.
15 elf-synthesising and self-repairing chemical factories.
16 viral membranes form de novo in cytoplasmic factories.
17 give structures reminiscent of transcription factories.
18 eutics, microbiome engineering and microbial factories.
19 s and thus represent specialized translation factories.
20 th the viral E3 protein in cytoplasmic viral factories.
21 psid assembly, functioning as viral assembly factories.
22 own as viral inclusion bodies (VIB) or viral factories.
23 itecture and biogenesis of viral replication factories.
24 ike structures, designated viral replication factories.
25 at the inclusion sites rather than in virus factories.
26 consistent with expression via transcription factories.
27 ould broadly facilitate design of novel cell factories.
28 ome occurs in cytoplasmic membrane-delimited factories.
29 ments for the formation of viral replication factories.
30 effect on established membranous replication factories.
31 entirely replicate within cytoplasmic virion factories.
32 of bromodeoxyuridine into viral replication factories.
33 virions within assembly sites of cytoplasmic factories.
34 atial organization and composition of repair factories.
35 occur at sites within the cytoplasm known as factories.
36 ATAD5 regulates the lifespan of replication factories.
37 er relatively stably to maintain replication factories.
38 the GpSGHV-induced colony collapse in tsetse factories.
39 vely recruit origins to emergent replication factories.
40 consistent with their sharing transcription factories.
41 ed sensors, reporter systems, and cell-based factories.
42 nes are transcribed in analogous specialized factories.
43 hock treatment, which disrupts transcription factories.
44 calized with virion membrane proteins in the factories.
45 leus, genes are transcribed in transcription factories.
46 rescent membranes, occurs within cytoplasmic factories.
47 on of RNA polymerase II around transcription factories.
48 titers requires efficient secretion by cell factories.
49 EBV late gene mRNAs localize to replication factories.
50 nfluence of the local 18(th) Century pottery factories.
51 polyhydroxyalkanoates (PHAs) producing cell factories.
52 the formation of replication-competent viral factories.
53 site for the development of future molecular factories.
54 at appear to function as viral transcription factories.
55 ution to viral replication and transcription factories.
60 specific cellular protein complexes to these factories aids efficient and controlled viral replicatio
62 hondria, so much more than just being energy factories, also have the capacity to synthesize macromol
63 replicates in round-shaped cytoplasmic viral factories, although how they assemble remains unknown.
64 ways to synthesize products using microbial factories and can pinpoint the contributions of microorg
66 L2 was detected in tubular membranes outside factories and inside factories near crescents and close
67 infection redistribute to viral replication factories and regulate the capacity of the virus to infe
68 lular RNA polymerase II was trapped in these factories and served to transcribe viral genomes, which
69 that these foci represent viral replication factories and that a cellular DNA damage response is act
70 naling intermediate Syk to cytoplasmic viral factories and this recruitment requires the mu2 ITAM.
71 ing to reveal the relationship between virus factories and viroplasm and the cellular structures that
72 d male smelter workers from an Mn-iron alloy factory and 23 gender- and age-matched controls were rec
73 anspoviron replicates within the giant virus factory and accumulates in high copy numbers inside gian
74 gated all workers (9) employed by a cosmetic factory and exposed to argan powder to identify possible
75 ATAD5-mediated regulation of the replication factory and PCNA required an intact ATAD5 ATPase domain.
76 e extruded promoter is tethered close to the factory and so likely to re-initiate; later, the tether
77 on of specialized transcription and splicing factories, and (3) the clustering of DNA double-strand b
78 lizes to ER-associated inclusions, the viral factories, and along microtubules before it is finally d
79 ructures, engineering the metabolism of cell factories, and analyzing human diseases is discussed.
81 of such optimally scheduled self-replicating factories, and find it has a universal form-log-Frechet,
82 the process of formation of viral inclusion factories, and taken together with earlier studies, sugg
83 Reovirus replicates in cytoplasmic viral factories, and there is no evidence that reovirus genomi
86 ere we show that H5 localizes to replication factories, as visualized by immunofluorescence and immun
89 rocess utilized by CVB for viral replication factory assembly, and depletion of RIP3 inhibits autopha
90 addition, MVs were shown to move from viral factories at speeds consistent with microtubular transpo
92 transcription within a common transcription factory become stabilized by antitopoisomerase II drugs
93 3, A14, D8, and H3 did not localize to viral factories but instead accumulated in the secretory compa
94 roach expands the chemical landscape of cell factories by providing alternative biosynthetic strategi
95 f ATAD5 extended the lifespan of replication factories by retaining proliferating cell nuclear antige
97 mone, using Nicotiana benthamiana as a plant factory, by transient expression of up to four genes cod
98 nsistent with a polymerase immobilized in a 'factory' capturing a promoter and reeling in the templat
101 delayed until early S phase and occurred in factories characterized by the absence of cellular DNA a
103 e of the reported diameter of "transcription factories." Colocalization measurements of RNAP II molec
105 ganized at discrete sites called replication factories, consisting of DNA polymerases and other repli
108 hese studies indicate that viral replication factories could end up in the phloem and the xylem.
109 plants, produce processing facilities, fish factories, cruise ships, family gatherings, parties, and
110 ountries each having one known solid cyanide factory: Czech Republic, Germany, and United States.
111 Focal assembly of "viral transcriptional factories" decreased the pool of cellular RNA polymerase
112 g new carbon capture technology or as a cell factory dedicated to formic acid production, which is a
114 e validation process revealed that autoclave factory default settings are potentially ineffective for
118 he core of viruses and assemble within viral factories, dynamic compartments formed within the host c
123 Experts identify more affordable unit cost, factory fabrication, and shorter construction schedules
124 tein, its large-scale production by means of factory farming is a major driver of biodiversity loss,
125 ers who had worked in metal mines or pottery factories for at least 1 year from January 1, 1960, to D
128 is now clear that they are more than simply factories for Ig production, and they also play key role
130 0% of the cells differentiate into anaerobic factories for nitrogen fixation (heterocysts), requires
131 developed genetic variants of microbial cell factories for production of biochemicals has been rapidl
132 perties as well as approaches to design cell factories for production of tailor-made bio-based materi
134 haromyces cerevisiae is among preferred cell factories for recombinant protein production, and there
135 a glandular trichomes and their potential as factories for the production of novel alternate sesquite
136 etabolic engineering of pathways in cells as factories for the production of simple compounds such as
138 ls the interior of infected cells to build a factory for assembling new infectious particles (virions
139 suggests that KSHV assembles an "all-in-one" factory for both gene transcription and DNA replication.
142 (RAV), that might serve as a portable, local factory for producing proteins destined for the secretor
145 ng (CALM), which turns bacterial cells into "factories" for generating hundreds of thousands of crRNA
146 of A. flavus gradually evolved into a "cell factory" for enzymes and metabolites involved in the sac
148 ection, we observed reduced ZIKV replication factory formation, as well as a 42-fold reduction in vir
150 scribe a protocol for the isolation of large factory fragments under isotonic salt concentrations in
151 ion gratings, and a dynamic surface template/factory from which various static micropatterns can be m
153 ng of cyanobacteria to create efficient cell factories has been impaired by the cumbersome genetic to
155 ls (CNS), waste from a cashew nut processing factory, have been used as an adsorbent for Pb(II) ions
156 of the hGH locus with polymerase II (Pol II) factories, histone acetylation at the hGH-N promoter, an
157 andful of genes have evolved into sequencing factories identifying thousands of variants of known and
158 Pase, SLIP-GC, that localizes to replication factories in B cells and that, when reduced, induces DNA
159 and E3 colocalized within cytoplasmic viral factories in cells infected with a decapping enzyme muta
160 of a cohort of 14,008 chemical workers at 6 factories in England and Wales, covering the period 1941
161 construction of entire functional metabolic factories in heterologous organisms, for example crop pl
162 sequester infectious virions outside of the factories in inclusion bodies comprised of numerous copi
163 strategy to assemble cytoplasmic replication factories in infected cells.IMPORTANCE Measles virus rem
164 embed infectious virus particles outside of factories in membraneless protein bodies with liquid gel
165 aradigm for the assembly of functional viral factories in other RNA viruses.IMPORTANCE The rotavirus
166 kers at two melamine tableware manufacturing factories in Taiwan (16 manufacturers, eight grinders, t
167 aintain a large number of unique biochemical factories in the form of singular plastids might be a ke
170 ainst a prevalent existence of transcription factories in the mammalian nucleus as previously propose
173 dings show that replication compartments are factories in which EBV DNA amplification is both clonal
174 Indeed, by up-grading treatment plants to factories in which the incoming materials are first deco
175 show that HSV-1 forms an organized assembly factory in neuronal cells, and we identify some of the v
176 n problem by creating a specialized assembly factory in the host cell, and the formation of such fact
177 viously been shown to form such an organized factory in the nonneuronal cells in which its assembly h
178 lymerases (pols) co-localize in 'replication factories' in vivo after cells are exposed to ultraviole
179 e thought of as a highly sophisticated micro factory: in a pool of billions of molecules - metabolite
182 nelles and highlight research on perinuclear factories induced by the nucleocytoplasmic large DNA vir
183 d interactions, most likely at transcription factories, initially compact the Igh locus, bringing dis
184 eins around the peripheries of virus-encoded factories, interrupting the normal formation of SGs.
186 mation of viral membranes within cytoplasmic factories is a mysterious, poorly understood first step
191 al and spatial regulation of the replication factory is important for efficient DNA replication.
192 y of starch to solubilise across a sugarcane factory is largely limited by increased Brix values.
193 the challenge in generating a superior cell factory is to fully exploit the production potential by
194 mpartment long regarded as the cell ribosome factory, is emerging as an important player in the regul
195 of the TC-muNS fusion proteins to form virus factory-like (VFL) structures and colocalize with virus
196 M and RGG domains of G3BP1 for maximal viral-factory-like structure (VFL) localization and sigmaNS as
197 th VFs in infected cells and also with viral factory-like structures (VFLs) formed by ectopically exp
199 sex, caste, standard of living, occupation, factory location, leisure time physical activity, daily
200 e monthly prevalence of smoking (overall, of factory-made cigarettes [FMC], and of roll-your-own toba
202 Thermostable enzymes and thermophilic cell factories may afford economic advantages in the producti
207 protein clusters analogous to transcription factories, multiscale loops, and intrachromosomal contac
208 bular membranes outside factories and inside factories near crescents and close to the edge or rim of
209 al distinctive nuclear bodies believed to be factories of DNA or RNA processing and sites of transcri
214 pronounced colocalizations in transcription factories, often near the nuclear periphery, and display
215 elongation without disrupting transcription factories once they are established, but the looping is
217 replicate in cytoplasmic compartments (virus factories or viroplasms) composed of viral and cellular
219 fundamental principles promoting replication factory organization in budding yeast, but also provides
224 ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA-unloading activity.
228 vestigated in lake Tyrifjorden, downstream a factory producing paper products coated with per- and po
229 in the host cell, and the formation of such factories provides a promising target for interfering wi
230 ble and insoluble starch (0-550 ppm/Brix) in factory raw sugars were investigated using simulated ref
231 DA Starch Research method as a reference and factory raw sugars, the impact of colourants on the accu
233 emain near the sites of transcription in the factory regions when stop codons are introduced near the
234 viruses replicate in specialized cytoplasmic factory regions where DNA synthesis, transcription, tran
235 this analysis, we propose that transcription factories result from the aggregation of RNA polymerase
236 ractions reveals that sequencing of purified factory RNA maps the complete nascent transcriptome; it
237 cruited into RNA polymerase II transcription factories (RNAPII-Ser5) and that ETO and RUNX1 genes are
238 roduction of ethanol by the widely used cell factory Saccharomyces cerevisiae was adopted as a case s
241 ontamination with M chimaera at the LivaNova factory seems a likely source for cardiothoracic surgery
242 the sort; however, iterative rounds of "cell factory" selection were required for the high-Env phenot
244 show that ESCO2 is recruited to replication factories, sites of DNA replication, through interaction
245 rise from membrane-enveloped RNA replication factories (spherules) containing VSV G protein that are
251 y, which comprises a highly organized virus "factory." TGB1 is both necessary and sufficient to remod
252 that these genomes accumulate in cytoplasmic factories that are delimited by membranes derived from t
253 hich occurs in clusters called transcription factories that are reminiscent of the dense phase charac
255 ing genes to be transcribed to protein-dense factories that contain all factors necessary for transcr
258 t also needs an efficient and well-organized factory that is responsible for the fidelity and quality
259 lic engineering, where cells are treated as 'factories' that synthesize industrial compounds, it is e
260 interpretation of nuclear RFi as replication factories, that is, the complex entities that process mu
261 ic chaperone function for Hsc70 within viral factories, the sites of reovirus replication and assembl
262 to isolate RNA associated with transcription factories, the sites responsible for the majority of nuc
263 l machinery to establish a virion production factory, the cytoplasmic virion assembly complex (cVAC).
265 amolecular complexes known as 'transcription factories.' These complexes are difficult to isolate bec
267 desired membrane transport proteins in cell factories to achieve the export or import of substances
268 A screens were only recently applied to cell factories to identify novel engineering targets which ar
269 ifically directed in granules or translation factories toward the tip of the developing daughter cell
270 that revealed intranuclear sun-shaped capsid factories, tubules, various stages of capsid formation,
271 eplicons dynamically organized a replication factory using live-cell imaging and investigate how repl
273 large inclusion-like structures called viral factories (VFs) in which assembling viral particles can
274 replicate within discrete cytoplasmic virus factories (VFs) that may represent a barrier to genome m
275 encoded cytoplasmic structures, termed virus factories (VFs), where viral transcription, translation,
276 s, mammalian orthoreovirus (MRV) forms viral factories (VFs), which are sites of viral transcription,
279 n of higher-order structures or replication "factories." We show that the key replication enzyme of f
280 cell imaging and investigate how replication factories were structured using super-resolution microsc
281 a wood-related industrial area, and a steel factory were 48, 160, and 1400 ng/g d.w., respectively,
283 equipped anywhere such as a laboratory or a factory where the VOCs are either used or produced and o
285 tes located downstream from a pharmaceutical factory, where reproductive alterations in wild fish hav
286 ssociated stochastically to form replication factories, which was validated by independent microscopy
287 n multiple puncta throughout the interior of factories, which were surrounded by endoplasmic reticulu
288 taneously aggregate to form transcriptional "factories," which recruited a significant fraction of ce
291 s led to an increase of inactive replication factories with an accumulation of replisome proteins.
292 rved colocalization of viral transcriptional factories with replicating viral genomic DNA suggests th
294 scovered that A11 colocalized in cytoplasmic factories with the endoplasmic reticulum (ER) and L2, an
295 r, across two field experiments with Chinese factory workers and American university staff, small adj
296 usiness professionals had low mortality, and factory workers and garment trade workers had high rates
298 mong professionals/administrators than among factory workers, with intermediate levels for other occu