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1 the rational planner, and it seems to us he fails to accommodate many of the interpersonal aspects o
2 ation, and we observed that existing methods fail to account for contaminated droplets and led to spu
5 hes to define specific HF subpopulations may fail to account for the diversity of etiologies, comorbi
6 (PCI) irrespective of indication for PCI may fail to account for the substantial risk of subsequent n
8 e subject to high levels of uncertainty, and failing to account for this uncertainty is liable to lea
10 We first determined that pax2a(-/-) embryos fail to accumulate F-actin in the OF prior to basement m
11 genes, the pivotal transcription factor PIF4 fails to accumulate, indicating a role of SPAs in regula
13 grow hBN monolayers on Cu (111) metals have failed to achieve mono-orientation, resulting in unwante
14 owever, to date, pharmacological agents have failed to achieve significant target engagement in vivo,
16 how cognition enables cultural learning, but fails to acknowledge a distinctively human behavior crit
17 ale heterozygous Mecp2 mutants (Mecp2(het) ) failed to acquire a learned maternal retrieval behavior
22 re (the proportion of women in which surgery failed to adequately resolve midline pain) and the frequ
23 ad altered expression of angiogenic factors, failed to adopt tip cell properties, and displayed reduc
25 ntional studies in which periodontal therapy failed to alleviate systemic health outcomes have often
26 phid (Rhopalosiphum padi), with high [CO(2)] failing to alleviate the aphid-induced decline in plant
27 B2, or GPR55 receptors in gene-knockout mice failed to alter BCP's action against cocaine self-admini
30 ake sperm-specific membranous organelles but fail to assemble their major sperm protein into fibrous
32 show that lone proteins and complex subunits failing to assemble in the ER access the INM for Asi-med
34 r actin filaments, many clathrin-coated pits fail to be severed from the membrane, causing accumulati
36 ed countermeasures against such attacks have failed to be effective, as they do not consider the util
38 egrees of severity in morbidity or mortality failed to be statistically significant because of survey
39 ies with promising outcomes in animal models failed to be translated to human disease, our platform a
41 he IET moves normally between the digits but fails to bifurcate because of abnormal adhesion of the p
43 e to bind Cul5 and some mutants additionally failed to bind A3G, ruling out competitive binding to A3
44 summary, single dose rapamycin pretreatment failed to block the antidepressant effects of ketamine,
45 During lytic infection, however, AcrIIA1 fails to block Cas9 due to its multi-step inactivation m
46 in other species, four Utricularia expansins failed to branch within any clade, suggesting that they
47 notation are limited to known cell types and fail to capture novel populations, especially cancer cel
48 nly used to assess HIV care cascade outcomes fail to capture such transitions and therefore incomplet
49 more than two APA isoforms, current methods fail to capture the entirety of APA changes and do not a
50 As such conventional optimization methods fail to capture the global optimum within the feasible s
53 s improved bulk tissue characterization, but fails to capture subtle thermal properties in heterogene
54 ects slow-evolving hemodynamic activity that fails to capture the faster timescale of normal physiolo
56 ient microglia phagocytose myelin debris but fail to clear myelin cholesterol, resulting in cholester
65 focus primarily on nitrogen or protein, and fail to consider carbohydrates, this study has important
69 ods of molecular (qPCR) and visual detection failed to contribute to the suppression of an exponentia
70 tive, but uncoordinated responses frequently fail to control disease, with a connection between aging
76 l therapies, imaging of myocardial viability failed to deliver effective guidance of coronary bypass
77 rgued that in the last 15 years nanomedicine failed to deliver the promised innovative clinical solut
80 ts who received intraarterial administration failed to demonstrate higher uptake by hepatic metastase
81 e showed the least benefit and in some cases failed to demonstrate significant weight gain despite nu
83 exponential and-more notably-logistic models failed to describe the experimental data whereas the Gom
84 re the main diagnostic tools for malaria but fail to detect low-density parasitemias that are importa
86 though initial genome analysis of crAssphage failed to detect related phages, or functionally annotat
89 eloped Chlamydia-specific intestinal IgA yet failed to develop IgA in the FRT, indicating that IgA re
90 he hypothesis that an innate immune response fails to develop following prostate infection with these
91 ecommendations are either silent about HF or fail to differentiate between the prevention of HF in th
92 f Vimentin, pluripotent embryonic stem cells fail to differentiate properly, with a pronounced defici
94 l to cumulative technological culture but it fails to discuss the implications for the emergence of c
97 ons where isotropic tension is elevated, but fail to do so in elongated cells within the crowded midl
100 study, we investigated why the immune system fails to effectively control a modified form of avian in
101 Here, we show that macrophages not only fail to efficiently kill phagocytosed S. aureus, but als
102 e spermatocytes arrest in prometaphase I and fail to either progress to anaphase or attempt spermatid
104 approaches for protein-based vaccines often fail to elicit potent and long-lasting immune responses.
105 ogenes mutant impaired in c-di-AMP secretion failed to elicit a protective response, whereas a mutant
106 cteria suggests that their rapid elimination failed to elicit the previously characterized response t
107 pletion of local fumarate, the DeltahemB SCV failed to elicit trained immunity and protection from a
110 kov process and discover that if the network fails to engage this stereotyped regime of motif dominan
111 host T(conv) and host T(regs), donor T(regs) failed to engraft even with interleukin-2 (IL-2) support
113 ons synergistically affected eosinophils but failed to enhance IL-13-driven effects on lung function
114 ter levels, unlike del(A420-A463) mutant, it failed to enhance mtDNA synthesis due to the accumulatio
115 s, eszopiclone increased spindle density but failed to enhance sleep-dependent procedural memory cons
118 ndependent mechanism of host cell death that failed to eradicate S. aureus and instead promoted Delta
120 ed is the presence of non-detects: reactions failing to exceed the quantification threshold and there
121 ategies to detect tumor cells (Sezary cells) fail to exclude reactive subsets, whereas tumor-specific
123 4 double knockout mouse embryonic stem cells fail to exit pluripotency and differentiate efficiently.
125 refers to elusive orbital interactions that fail to explain short interatomic contact distances.
127 sical 12/23 rule for the V(D)J recombination fails to explain the V(DD)J recombination, the molecular
129 elations and ignore inter-sentential ones or fail to extract inter-sentential relations accurately an
133 a-analyses of this literature, however, have failed to find statistically significant between-study s
136 ension produced regular CLPs in bacteria but failed to form stable nucleocapsids in hepatoma cells.
139 1, its phenotypic variant, termed as F-type, fails to form spores, does not confer plant growth-promo
140 of a C(32-)A(38) cross-loop interaction but failed to fully explain the means by which s(2)C(32) res
141 lted in suppression of virus replication but failed to fully restore T-cell function and eliminate HB
142 chronically exposed cells for up to 1 month failed to fully reverse the transcriptional and phenotyp
143 omparison of peaks across different samples, failing to fully exploit the information available from
144 oxo1 actively repressed CD127 expression and failed to generate memory precursors and long-lived memo
147 into wild-type recipient, Cosmc-null B cells fail to home to lymph nodes as well as non-lymphoid orga
148 ple, we observed that existing methods often fail to identify 10% contaminated samples at a typical 3
150 guidelines for referral for genetic testing failed to identify 6 (26%) patients with high-penetrance
152 rm of the translocon of inner membrane, they failed to identify any outer-membrane translocon homolog
153 In contrast, neuroimaging investigations failed to identify cerebral features associated with fat
154 e will develop FXTAS, as clinical assessment fails to identify carriers at risk before significant ne
155 analyzing physical and biological variables fails to identify the significant association for walley
156 ic institutions and departments have largely failed to implement these recommendations, which has exa
161 a2delta-1 gene KO mice, treatment with FK506 failed to increase the frequency of NMDAR-mediated mEPSC
166 necrosis factor alpha (TNF-alpha) and vgRNA failed to induce NF-kappaB-dependent gene expression in
167 Expression of Akt3 in p47 (phox-/-) MEFs failed to induce ROS and to inhibit cell proliferation.
168 alanine (Ala) substitution at amino acid 79, failed to induce these phenotypes, indicating that Thr 7
169 natants from biopsies of patients with IBS-D failed to induce visceral hypersensitivity or increase t
170 ctive photoreceptors, even though the mutant fails to induce the expression of photosynthesis-associa
171 n-1(S714A) mutant and found that this mutant failed to infect mice, suggesting that the proteolytic a
172 at, in del10 homozygotes, neural crest cells fail to infiltrate the developing SV intermediate layer.
173 GABA transaminase inhibitor vigabatrin also failed to influence glucagon secretion at 1 mm glucose a
176 in-resistant animals, portal vagal afferents failed to inhibit their spiking activity during glucose
177 organized processes from denervated NMJs and failed to initiate or guide nerve terminal sprouts at di
179 MLAV VP24 differed from MARV VP24 in that it failed to interact with Keap1 or activate an antioxidant
180 +/- 7.2% for IVF and 73.3 +/- 8.1% for ICSI) failed to litter after embryo transfer compared to embry
181 s that disrupt its association with Swi6/HP1 fail to localize to heterochromatin, lead to accumulatio
183 ts multiple configurations in the pocket and fails to make an interaction critical for activation by
188 he proposed donation rate standard, 36 (62%) failed to meet the proposed organ transplant rate standa
189 iant, we demonstrate that neural crest cells fail to migrate into the stria vascularis intermediate l
192 ided competence stimulating peptide 1 (CSP1) failed to modulate the onset kinetics of competence deve
193 t cGAS sensing pathway, human CD4(+) T cells failed to mount a reverse transcriptase (RT) inhibitor-s
194 expression of FoxO3a and liver kinase B1 but fails to normalize impaired PPAR-alpha expression or met
195 st extreme case, almost a third of observers failed to notice when less than 5% of the visual display
196 Using these models in vivo and in vitro, we fail to observe a requirement for phosphorylation in NLR
199 smaller groups to grow relatively slowly or fail to persist (termed group-level demographic Allee ef
200 arranged to enable high information transfer fails to predict auditory pathway organization and has s
201 ng catabolic pathways have, however, largely failed to preserve muscle mass in cachexia, suggesting t
203 ut piRNA-dependent silencing: deps-1 mutants fail to produce the secondary endo-siRNAs required for t
204 to our surprise, plasmid-deficient Chlamydia failed to produce infectious progenies in small intestin
205 ed an ORF66-null virus and confirmed that it fails to produce late genes and infectious virions.
206 While standard linear interpolation mostly fails to produce realistic transitions, our method yield
208 However, our study showed that these cells failed to proliferate in the presence of rigosertib at c
209 the accumulation of bile acids in the liver, fails to promote liver injury in the absence of the micr
210 d transcriptome misregulation, as cht7 cells fail to properly arrest growth, nuclear replication, and
212 ces synthesis of membrane proteins that have failed to properly assemble in the endoplasmic reticulum
219 nonetheless it should be underlined that by failing to provide characteristics of the particles, an
220 p than in the ODRH group (8% vs. 3%), but it failed to reach statistical significance (P = 0.167).
221 mall intestinal pGP3-deficient Chlamydia sp. failed to reach the large intestine, explaining the lack
223 e six remaining PubMLST loci (0.897, 79 STs) fails to reach the benchmark recommended for a reference
224 However, selective ERK5 kinase inhibitors fail to recapitulate ERK5 genetic ablation phenotypes, s
225 f traditional cell culture techniques, which fail to recapitulate mechanobiologic stimuli known to af
226 ntact body physiology, and at the same time, fail to recapitulate the extensive features of the tumor
227 -interact and that the rod-shaped structures failed to recognize glycoprotein E, the well-known bindi
228 -infected immunological non-responders (INR) fail to reconstitute their CD4 + T cell pool after initi
229 oring a macrophage-specific deletion of BCAP fail to recover from and succumb to dextran sulfate sodi
230 n-labeled vacuoles containing L. pneumophila failed to recruit autophagy adaptors by a process that w
233 51-isavuconazole complex, the protein target failed to refold 74 N-terminal residues, suggesting a fu
235 h injury, centrally-projecting sensory axons fail to regenerate across the dorsal root entry zone (DR
237 to near baseline, LSD1-deficient CD8 T cells failed to remethylate the Pdcd1 locus to the levels of w
241 iants identified in the affected individuals fail to rescue the loss of Cdk8 and behave as null allel
245 erapeutics remains limited, as many patients fail to respond for reasons that still largely evade und
247 sive to psychotherapy treatment for PTSD and failed to respond to an antidepressant medication for MD
248 y reinvigorates exhausted CD8(+) T cells, it fails to restore T cell repertoire diversity.IMPORTANCE
250 c oxide synthase 2 (NOS2)-deficient mice all failed to reveal an effect of P2C/5-OP-RU-induced MAIT c
253 shown to have rapid antidepressant effects, fails to reverse elevated arousal to distal threat contr
261 However, Smoothened (SMO) inhibitors have failed to show clinical benefit in patients with cancers
262 ticipants with obesity, the patients with AN failed to show functional connectivity between the hypot
266 rage and patient-perceived esthetic outcomes failed to show significant differences between CTG and G
267 he absence of the fork remodeler HLTF, forks fail to slow following replication stress, but underlyin
269 SCF-FBXL17 disrupts aberrant BTB dimers that fail to stabilize an intermolecular beta-sheet around a
270 drenaline) when ventilation and compressions fail to stabilize the newborn infant, appropriate routes
273 d dendritic cell-induced proliferation, they failed to sufficiently regulate T cells stimulated by an
279 on (ABC) supports two possible scenarios but fails to tease apart whether admixture or divergence pro
282 called confounders, produce embeddings that fail to transfer to different domains, i.e. an embedding
283 margin can maintain RPE fate ectopically and fail to transition from neuroepithelial to cuboidal shap
289 nternalized through endocytosis, but capsids fail to uncoat and accumulate within LAMP1(+) endolysoso
290 re, we demonstrate that HLTF-deficient cells fail to undergo fork reversal in vivo and rely on the pr
292 tead a remnant effector cell population that failed to undergo initial contraction has remained uncle
293 isation and early fixation of fractures that fail to unite in adults with scaphoid waist fractures di
295 t enhanced retinal Cd40 mRNA translation and failed to up-regulate expression of the inflammatory mar
297 -Ser754 STAT3 relative to phospho-Ser727 and fail to upregulate the STAT3 target Socs3, which is requ
299 tants can be subject to compensation, or may fail to yield a null phenotype due to leakiness (e.g. us
300 However, these group-level observations have failed to yield any biomarkers that can provide confirma