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1 , no double-lumen tube positioning method is fail-safe.
2  data reveal the workings of an evolutionary fail-safe, a duplicate enhancer mechanism that is hard-w
3                                  A Rosenthal fail-safe analysis revealed that 180 092 null studies wo
4 nd angiogenesis and reveal the presence of a fail-safe antiproliferative mechanism.
5 6/Cdkn2a expression is induced, serving as a fail-safe brake to proliferation in the absence of the p
6                                              Fail-safe calculations reflecting the number of unpublis
7 her necroptosis, conventionally considered a fail-safe cell death mechanism to apoptosis, can restric
8 aightforward mechanistic explanation for the fail-safe cellular senescence response elicited by acute
9                                  We designed fail-safe codes and simulated their expected effects on
10                                   We predict fail-safe codes supporting expression of 20 or 15 amino
11                                              Fail-safe design of devices requires robust integrity as
12                          For larger areas, a fail-safe design should be based on a maximum 57 GPa str
13 n has been that alternative nitrogenases are fail-safe enzymes that are used in situations where moly
14 ity of host/virus interactions and suggest a fail-safe escape mechanism by virus-infected cells for e
15 dal expression of RBP9, providing a maternal fail-safe for dosage compensation.
16 ng assumptions for valid IV analyses are not fail-safe, in that there are situations where the approa
17 exposure was sufficient to operate a two-LED fail-safe indicator circuit.
18 e of multiple pathways may be important for "fail-safe" induction and maintenance of cell cycle arres
19 ream open reading frames (uORFs) acting in a fail-safe manner to inhibit the translation from the mai
20 itiator production, RepC/C* could serve as a fail-safe means of preventing autocatalytic replication.
21 inding mode with the channels, possibly as a fail-safe measure to ensure a correct binding sequence.
22  autocrine regulation, APCs have an inherent fail-safe mechanism against inappropriate activation and
23 ne-induced senescence (OIS) that serves as a fail-safe mechanism against malignant transformation.
24 be components of an evolutionarily conserved fail-safe mechanism by which animals protect against neo
25 uced, nondeletional tolerance can serve as a fail-safe mechanism by which clones of autoeffector T ce
26  Cleavage at this site is probably part of a fail-safe mechanism by which trypsin, which is activated
27 ing secondary necrosis provides an important fail-safe mechanism counteracting inflammatory responses
28                         This appears to be a fail-safe mechanism ensuring that the active sites on th
29 The presence of two triggers may represent a fail-safe mechanism ensuring the timely reset of the rep
30 cted distance from the membrane, providing a fail-safe mechanism for a diverse cargo repertoire.
31 lexibility in the sequences eliminated and a fail-safe mechanism for PDE.
32 nsuring chromosomal breakage and providing a fail-safe mechanism for PDE.
33  reinforcing and evolutionarily advantageous fail-safe mechanism for respiratory rhythmogenesis in ma
34     Apoptosis induced by c-Myc is a critical fail-safe mechanism for the cell to protect against unre
35                         Our results reveal a fail-safe mechanism for the surveillance of unwanted tra
36 ammatory response, suggesting evolution of a fail-safe mechanism for tissue protection each time infl
37 ial role for Taz in a previously undescribed fail-safe mechanism in aging HSCs.
38                                  This robust fail-safe mechanism is eventually bypassed by transforme
39 K kinase activity has a critical role in the fail-safe mechanism of IRES-dependent translation when m
40 ne, initiates a liver-specific translational fail-safe mechanism that deters protein synthesis under
41 rough cohesin rings has been envisioned as a fail-safe mechanism that ensures co-entrapment of replic
42  not serve as a degron, but rather provide a fail-safe mechanism that expands the range of RQC-degrad
43 ality reveals a novel, enzymatically encoded fail-safe mechanism that may help Mtb and other bacteria
44 usceptible to GCV, representing an effective fail-safe mechanism to abolish viral replication in a cl
45 ur data indicate that miR-196 functions in a fail-safe mechanism to assure the fidelity of expression
46 erization via CD40:CD40L blockade provides a fail-safe mechanism to control alloreactive T cells that
47 athway in mammalian cells serves mainly as a fail-safe mechanism to ensure efficient secretion of sma
48 ing relative to other components serves as a fail-safe mechanism to ensure that septal PG synthesis p
49 -mRNA splicing, and we interpreted this as a fail-safe mechanism to ensure the cotranscriptional recr
50 ative stress response program that acts as a fail-safe mechanism to limit oncogenic transformation an
51  implies that premature senescence acts as a fail-safe mechanism to limit the transforming potential
52 at AID-induced damage at telomeres acts as a fail-safe mechanism to limit the tumor promoting activit
53 kpoint (or spindle assembly checkpoint) is a fail-safe mechanism to prevent chromosome missegregation
54  from natural infection or serve solely as a fail-safe mechanism to prevent overt disease in infected
55 t inefficient Xist splicing is an additional fail-safe mechanism to prevent Xist activity in ES cells
56 cripts are degraded by NMD, which provides a fail-safe mechanism to remove spurious transcripts that
57 distribution away from germ blastomeres is a fail-safe mechanism, protecting embryo development and m
58  next-generation lithium-metal batteries, a "fail safe" mechanism for internal short is highly desira
59 e y-subunit, as proposed before, but also a "fail-safe" mechanism involving the b'-subunit in the per
60 uggest that the Zap1-activated LLT RNA is a "fail-safe" mechanism to ensure decreased Hnt1 protein in
61  results suggest that Ad12 likely employs a "fail-safe" mechanism to ensure that the transcription of
62  of participation of autocrine TGFbeta in a "fail-safe" mechanism to generate cell death in response
63    These data support the idea of a central "fail-safe" mechanism whereby hypoglycemia can override t
64  studies of PRC1 occupancy also suggested a "fail-safe" mechanism, whereby PRC1/Bmi1 concentrates at
65                                Biologically, fail-safe mechanisms identified by the ab initio approac
66                                 One of these fail-safe mechanisms is mediated by the NRD complex, sim
67 ion upstream of quality control pathways and fail-safe mechanisms that ensure nascent proteome integr
68  mechanisms to partially bypass the multiple fail-safe mechanisms that protect against cleavage of ge
69                  Thus, Pab1p and CPF provide fail-safe mechanisms to a primary Nab2p-dependent pathwa
70 ape from host vacuoles and utilizes multiple fail-safe mechanisms to avoid causing toxicity to infect
71 lay pivotal roles in signaling and represent fail-safe mechanisms to prevent self-nucleic acid recogn
72                       The immune system uses fail-safe mechanisms to suppress infection-associated ti
73 nt of safe vectors for gene therapy requires fail-safe mechanisms to terminate therapy or remove gene
74            Thus, pRb loss triggered multiple fail-safe mechanisms whereby urothelial cells evade tumo
75 nuniform across the genome, and has built-in fail-safe mechanisms, features that are in keeping with
76     The auto-inhibitory plus the associated "fail-safe" mechanisms and the modes of attachment of the
77                     An extension, called the fail-safe model, envisaged an optimum level of gene dera
78 idity and applicability of the continuum and fail-safe models.
79 homogeneity (Q and I2) and publication bias (fail-safe N and funnel plots) were also examined.
80                   Trim and fill analyses and fail-safe n calculations suggest that the results are no
81                                          Low fail-safe N estimates reduce confidence in the observed
82 NS parameters was assessed using Rosenthal's fail-safe N.
83 ty, T(2)=0.04; I(2)=22.75%; and high classic fail-safe N=240).
84                                 According to fail-safe number statistics, the evidence levels are unl
85 lication bias in these reports, although the fail-safe numbers were 2,020 and 750 for healthy and dis
86 ables autoreactive B cells to circumvent the fail-safe of T cell tolerance.
87 dback regulators that may have overlapping ("fail-safe") or specific functions.
88 ulates LCRs and Ca transient decay to insure fail-safe pacemaker cell operation within a wide range o
89 and flexible cell death system with in-built fail-safe processes that protect the host from intracell
90  urchin embryo reveal a sequence of encoded "fail-safe" regulatory devices.
91 s show that Runx2 and MYC overcome distinct "fail-safe" responses and that their selection as collabo
92        Functionally, both components of this fail-safe silencing mechanism are required to prevent ec
93 gulated by multiple pre- and post-activation fail-safe steps.
94 xed mechanism of transformation results in a fail-safe strategy for the population as half of the pop
95  activation of p53 and JNK may constitute a "fail-safe" switch for the JNK-dependent apoptotic respon
96                  Instead, it may represent a fail-safe system in case of impaired hypoglycemia sensin
97                         This may represent a fail-safe system that protects the host against genetic
98 d citrulline recycling via Ass1 and Asl is a fail-safe system that sustains optimum NO production.
99 RFs and the three proteins formed a multiple fail-safe system that tightly inhibits the translation o
100 hese coordinated signaling pathways ensure a fail-safe system to prepare the oocyte for fertilization
101 his bimodal control mechanism may comprise a fail-safe system, such that transcription of the ftsQA g
102                           This feed forward "fail safe" system, kept in check by a high basal phospho
103                                         Both fail-safe termination mechanisms trigger degradation of
104  hairpin-dependent termination, one or more "fail-safe" termination mechanisms may exist in the cell.
105 h the +93 site quantitatively terminate at a fail-safe terminator located further downstream at +250.
106 ctions as a "biological fuse" in providing a fail-safe that immediately halts iron release once ROS a
107                 Such a mechanism provides a "fail-safe" that prevents neurons from dying by accidenta
108     However, solar geoengineering may not be fail-safe to prevent global warming because CO(2) can di
109 ation of short noncoding RNA genes and for a fail-safe transcriptional termination mechanism of prote
110 ggered on viral amplicons further guaranteed fail-safe virus detection.

 
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