ライフサイエンスコーパス: faithful

1 t is vitally important for replication to be faithful.

2 rearing), bolder individuals were more site-faithful.

3 s problem, we developed a method to obtain a faithful 3D reconstruction of the mouse body that enable

4 ace of unpredictability; 2) how to carry out faithful analysis of system behavior with respect to ric

5 ired resistant mechanisms, which may be more faithful and comprehensive than the ones revealed throug

6 Preclinical studies in faithful and informative mouse models, in concert with k

7 ese repair intermediates could generate both faithful and mutagenic repair.

8 se findings suggest that B35DNAP may perform faithful and processive genome replication in vivo and,

9 umour suppressor genes and the generation of faithful animal models of human cancer.

10 mer based on the clade A BG505 sequence is a faithful antigenic and structural mimic of the native tr

11 ity in the generative model to enable a more faithful approximation to exact inference.

12 We found that P2K1 function is crucial for faithful ATP-induced transcriptional changes and that a

13 en concepts, making it possible to recover a faithful bidimensional representation of the semantic sp

14 The preprophase band (PPB) is a faithful but transient predictor of the division plane i

15 current bioprinting strategies for achieving faithful cancer modeling.

16 Faithful cell cycle progression in the dimorphic bacteri

17 in turnover of several factors critical for faithful cell cycle progression.

18 oper chromosome segregation is essential for faithful cell division and if not maintained results in

19 le localization of Aurora B is essential for faithful cell division, it is unknown whether interferen

20 nable chromosome segregation and orchestrate faithful cell division.

21 r chromatids during anaphase is critical for faithful cell division.

22 n of the TF network by Cdk1 is necessary for faithful cell division.

23 The fundamental requirement for faithful centromere inheritance is the controlled deposi

24 t function of RIPK1 and Caspase-8, promoting faithful chromosome alignment in mitosis and thereby ens

25 catch-all enzyme of last resort that allows faithful chromosome segregation and cell division to occ

26 sotropic and rigid form they need to undergo faithful chromosome segregation and division in a crowde

27 rine 7 maintains correct CENP-C recruitment, faithful chromosome segregation and long-term cell viabi

28 ells usually adopt a rounded shape to ensure faithful chromosome segregation and to promote morphogen

29 totic spindle assembly is a prerequisite for faithful chromosome segregation and unperturbed cell-cyc

30 er division plane positioning is crucial for faithful chromosome segregation but also influences cell

31 aling system, the mitotic checkpoint ensures faithful chromosome segregation by delaying anaphase ons

32 In animal cells, faithful chromosome segregation depends on the assembly

33 Faithful chromosome segregation depends on the precise t

34 res to bind spindle microtubules and promote faithful chromosome segregation during cell division.

35 Faithful chromosome segregation during meiosis I depends

36 hus ensuring proper kinetochore assembly and faithful chromosome segregation during meiosis.

37 rganization of the mitotic spindle to ensure faithful chromosome segregation during mitosis, cell pol

38 e-mediated regulation of PLK1 contributes to faithful chromosome segregation during mitosis.

39 Aurora B kinase is essential for faithful chromosome segregation during mitosis.

40 We conclude that faithful chromosome segregation for most of human chromo

41 Faithful chromosome segregation in all eukaryotes relies

42 The kinetochore drives faithful chromosome segregation in all eukaryotes, yet t

43 Mitotic SUMOylation has an essential role in faithful chromosome segregation in eukaryotes, although

44 s, an important safeguard mechanism ensuring faithful chromosome segregation in eukaryotic cells.

45 Faithful chromosome segregation in meiosis requires cros

46 f Aurora B at the inner centromere to ensure faithful chromosome segregation in metazoans.

47 somal cohesin complex, is a prerequisite for faithful chromosome segregation in mitosis.

48 inase-dependent Aurora B pool that supported faithful chromosome segregation in otherwise unchallenge

49 exerts post-fertilization control to ensure faithful chromosome segregation in the embryo.

50 f chromosomes from the NE being required for faithful chromosome segregation in yeast and segregation

51 iscrete structures-processes fundamental for faithful chromosome segregation into daughter cells.

52 Faithful chromosome segregation is accomplished by attac

53 Faithful chromosome segregation is required for both mit

54 ase Aurora B as a catalytic subunit, ensures faithful chromosome segregation through destabilizing in

55 Faithful chromosome segregation with bipolar spindle for

56 Despite the essentiality for faithful chromosome segregation, centromere architecture

57 ole in many biological processes: it ensures faithful chromosome segregation, regulates gene expressi

58 n ATR pathway acts at centromeres to promote faithful chromosome segregation, revealing functions of

59 s to correct improper attachments and ensure faithful chromosome segregation.

60 to trigger DNA-repair synthesis that ensures faithful chromosome segregation.

61 ation imposed by Ipl1 kinase is critical for faithful chromosome segregation.

62 dk1 destabilizes k-MT attachments to promote faithful chromosome segregation.

63 d mitotic chromosome organization to support faithful chromosome segregation.

64 gulating removal of centromeric cohesins and faithful chromosome segregation.

65 hment of sister chromatid cohesion to ensure faithful chromosome segregation.

66 of the kinetochore and is required to ensure faithful chromosome segregation.

67 ial to link homologous chromosomes and drive faithful chromosome segregation.

68 s Cse4 from Psh1-mediated ubiquitination for faithful chromosome segregation.

69 y, and its mechanical disruption compromised faithful chromosome segregation.

70 ensures high levels of cohesin and promotes faithful chromosome segregation.

71 rotubule depolymerase activity essential for faithful chromosome segregation.

72 assembles on centromere DNA is required for faithful chromosome segregation.

73 l to ensure progression through anaphase and faithful chromosome segregation.

74 in remodeling SUMOylated proteins to ensure faithful chromosome segregation.

75 tion, promoted by separase, is essential for faithful chromosome segregation.

76 ription, replication, DNA damage repair, and faithful chromosome segregation.

77 Centromeres provide a pivotal function for faithful chromosome segregation.

78 le for Cdc5-mediated Cse4 phosphorylation in faithful chromosome segregation.

79 oisomerase II (TOP2) plays a pivotal role in faithful chromosome separation through its strand-passag

80 As H2B S6ph is important for faithful chromosome separation, this modification may co

81 osome in maintaining centromere function and faithful chromosomes segregation.

82 on, provides a molecular memory that ensures faithful commitment to transcriptional programs during m

83 Fasting is a religious practice to which the faithful comply strictly.

84 able quantum technologies may be achieved by faithful conversion between matter qubits and photonic q

85 ompeting myogenic program and directs a more faithful conversion to neuronal cells.

86 This faithful CRC model provides genetic evidence that Kras(m

87 romeres, bind spindle microtubules to ensure faithful delivery of chromosomes during cell division.

88 These trans-acting factors enable the faithful delivery of seven Sm proteins onto snRNA and th

89 be studied in native-like media to achieve a faithful description of their function.

90 transcriptional perturbations and allows for faithful detection of both baseline transcriptional prof

91 noise to the detected signal and demonstrate faithful detection of pico-second single photons.

92 ell junctions, is of vital importance to the faithful detection of weak directional signals, and beco

93 Here we show that ptk7 mutant zebrafish, a faithful developmental model of IS, exhibit defects in e

94 TCF4 served as a faithful diagnostic marker of BPDCN, and its downregulat

95 nt "MISTRG" mice that provides efficient and faithful disease representation across all MDS subtypes.

96 odies (SPBs) in fungi, are important for the faithful distribution of chromosomes between daughter ce

97 together with the mitotic spindle ensure the faithful distribution of chromosomes between daughter ce

98 e constriction with septation is critical to faithful division in Gram-negative bacteria and vital to

99 Faithful DNA repair is essential to maintain genome inte

100 Cell cycle regulation, especially faithful DNA replication and mitosis, are crucial to mai

101 lation of RNA processing is needed to ensure faithful DNA replication and repair.

102 counteracts replication stress and promotes faithful DNA replication consists of the Fanconi anemia

103 Faithful DNA replication is a cornerstone of genomic int

104 Faithful DNA replication is essential for genome stabili

105 zation of DNA into nucleoids, controlled and faithful DNA replication, chromosome unlinking and faith

106 nome stability underscores the importance of faithful DNA replication.

107 eckpoint activity and H3K4me are crucial for faithful DNA synthesis under replication stress, especia

108 B35DNAP is a highly faithful DNAP that can couple strand displacement to pro

109 n parasite Trypanosoma brucei depends on the faithful duplication and segregation of multiple flagell

110 ear antigen (PCNA) lies at the center of the faithful duplication of eukaryotic genomes.

111 arge variability mediate a trade-off between faithful encoding and optimal coding via temporal whiten

112 esponsible for genome replication are highly faithful enzymes that nonetheless cannot deal with damag

113 indings reveal a requirement for HP1gamma in faithful establishment of transcription elongation in ES

114 per 10(6)-10(8) incorporations) and support faithful eukaryotic genome replication.

115 Faithful execution of developmental programs relies on t

116 Cell fate determination requires faithful execution of gene expression programs, which ar

117 these insights to inform the development of faithful experimental models to test the efficacy of new

118 Our work establishes a robust and faithful experimental system of the early events of epig

119 With the development of more faithful experimental systems and continued study, we an

120 of eGFP-labeled hippocampal cells confirmed faithful expression of eGFP within GHSR-containing, ghre

121 n isomorphic nucleoside analogue acting as a faithful fluorescent substitute of G, with respectable q

122 Faithful gamete formation through meiosis requires that

123 utation in the early coding region, ensuring faithful gene knockout.

124 that, as well as generally acting to ensure faithful genetic inheritance, SMCs can disrupt genome st

125 of DNA before cell division is essential for faithful genetic inheritance.

126 s a logical framework for the development of faithful genetic models and new therapeutic approaches.

127 ing heterologous differentiation, yielding a faithful genetically engineered model of this cancer typ

128 Faithful genome duplication and inheritance require the

129 ow cyclin A levels during the G(1) phase for faithful genome duplication and segregation.

130 that it plays an important role in securing faithful genome duplication.

131 Faithful genome propagation requires coordination betwee

132 To ensure faithful genome propagation, mitotic cells alternate one

133 Faithful genome transmission during cell division requir

134 phorylation for proper spindle formation and faithful genomic transmission.

135 Overall, we provide a faithful H3.3(K27M)-pHGG model which enables insights in

136 nt studies in Drosophila cells revealed that faithful homologous recombination (HR) repair of heteroc

137 Ensuring faithful homologous recombination in allopolyploids is e

138 G from Escherichia coli, we demonstrate that faithful images of 2D crystalline and non-crystalline me

139 est that black-browed albatrosses are highly faithful in their foraging habitat but it is rather site

140 , detect very rare phenotypes, and construct faithful in vitro disease models.

141 nduced pluripotent stem cells can serve as a faithful in vitro platform to better understand the unde

142 to predict residues of the RdRp required for faithful incorporation of nucleotides represents an esse

143 esults show that hemodynamic signals are not faithful indicators of the mean neural activity in the f

144 insidious because neither base in it carries faithful information to direct the repair of the other.

145 The spindle assembly checkpoint ensures the faithful inheritance of chromosomes by arresting mitotic

146 To ensure the faithful inheritance of DNA, a macromolecular protein co

147 city of nuclear RNAi in C. elegans, ensuring faithful inheritance of epigenetic memories.

148 In mammals, faithful inheritance of genomic methylation patterns ens

149 highly condensed mitotic chromatin to ensure faithful inheritance of prior accessibility status acros

150 struction at the end of prophase I to ensure faithful inheritance of the genome.

151 subsequent anchorage at its tip ensures the faithful inheritance of this organelle.

152 DNA polymerases facilitate faithful insertion of nucleotides, a central reaction oc

153 arly the C-nucleosidic purine analogues, are faithful isomorphic and isofunctional surrogates of thei

154 propose a latent variable model to discover faithful low-dimensional representations of high-dimensi

155 Faithful maintenance and propagation of eukaryotic genom

156 Cell proliferation and survival require the faithful maintenance and propagation of genetic informat

157 This was accompanied with a faithful maintenance of DNAme in the breast cancer impla

158 Faithful maintenance of immune homeostasis relies on the

159 Due to the lack of faithful markers to distinguish CD8-MP cells from bona f

160 Faithful meiotic chromosome inheritance and fertility re

161 Faithful meiotic chromosome segregation and fertility re

162 conserved regulatory mechanisms that ensure faithful meiotic chromosome segregation in diverse speci

163 n homologous chromosomes is required for the faithful meiotic segregation of chromosomes and leads to

164 roning hydrophobic transmembrane helices for faithful membrane insertion.

165 nt implications for the use of cell lines as faithful mimics of in vivo epigenetic and physiological

166 onal modification of mitochondrial tRNAs for faithful mitochondrial function.

167 1-mediated mtDNA processing is essential for faithful mitochondrial genome replication and might be r

168 stalks with the actin cytoskeleton to ensure faithful mitosis and spindle positioning is unclear.

169 pVHL in mediating oriented cell division and faithful mitotic checkpoint function in the renal epithe

170 Faithful mitotic chromosome segregation is required for

171 ously undescribed mechanism for interrupting faithful mitotic progression and may ultimately inform t

172 em to mTOR signaling in a pathway to promote faithful mitotic progression.

173 Using the RCS cell line as a faithful model for proliferating/early prehypertrophic g

174 This study was designed to generate a more faithful model of Parkinson's disease by injecting human

175 enotypes in primates, we must have access to faithful model systems for a wide range of cell types.

176 Although faithful modeling of a genetic risk factor poses many ch

177 uggest that stiffening hydrogels may be more faithful models for studying myofibroblast activation th

178 n cancers, which frequently lack alternative faithful models.

179 g, so that all cleaved RNAs are committed to faithful modification.

180 ho can entrain to an external beat have more faithful neural encoding of temporal modulations in spee

181 to the correctness of the bound nucleotide, faithful nucleotide incorporation is achieved.

182 gi in regulating spindle formation to ensure faithful organelle inheritance.

183 ad lower subsequent breeding propensity than faithful partners.

184 We have developed faithful patient-derived RMC models and using whole-geno

185 mmary, we have established and characterized faithful PDX models of DLBCL and demonstrated their usef

186 and B-family DNA polymerases which possess a faithful polymerase activity that preferentially incorpo

187 imulations have indicated that efficient and faithful polymerase function requires highly coordinated

188 Here, we take advantage of a faithful primary neuronal model of ALS and FTD to invest

189 nce modulation SICM scheme allows reasonably faithful probe positioning using the resulting ac respon

190 ns unclear how they act in concert to ensure faithful processing of the damage signal.

191 anillin-actin interaction modes promote the faithful progression of cytokinesis.

192 ed replisome progression is required for the faithful propagation of DNA methylation throughout the c

193 of neurons at each processing stage enables faithful propagation of kinematic representations throug

194 Faithful propagation of life requires coordination of DN

195 Faithful propagation of transcription programs through c

196 sembly of the large ribosomal subunit and in faithful protein production.

197 The folding probe strategy and the faithful quantification of a particular protein's functi

198 nts and simulations and that finally allow a faithful quantification of the magnetic force for the lo

199 s and Trp53 transgenes, is well regarded for faithful recapitulation of human pancreatic cancer biolo

200 This faithful recapitulation of tissue-specific fate post-tra

201 data transmission and storage, we obtained a faithful reconstruction of the 3D volumetric information

202 e histone modification landscape that allows faithful reestablishment of the transcriptional program

203 chromosome (nucleoid) conformation dictates faithful regulation of gene transcription.

204 The difference between faithful repair and wreaking mutagenic havoc on the geno

205 cess in all living organisms that allows the faithful repair of DNA double strand breaks, through the

206 tic data, demonstrating that it converges to faithful replica of test functions more rapidly than com

207 s a multiprotein machine responsible for the faithful replication of chromosomal and plasmid DNA.

208 at replication forks promotes efficient and faithful replication of chromosomal DNA.

209 e accuracy of such a model is validated by a faithful replication of the experimental cryo-EM map com

210 fidelity of the FMDV polymerase and ensuring faithful replication of the FMDV genome.

211 Efficient and faithful replication of the genome is essential to maint

212 ys that ensure the repair of damaged DNA and faithful replication of the genome.

213 Faithful replication of the mitochondrial genome is carr

214 Hence, CtIP is required for faithful replication through telomeres via its roles at

215 tructures to facilitate fork progression and faithful replication.

216 the hPolepsilon holoenzyme an efficient and faithful replicative DNA polymerase.

217 Faithful reporting of temporal patterns of intracellular

218 To ensure a faithful representation of cellular metabolism after cel

219 d superficial muscles and thus can provide a faithful representation of the neural drive sent to a mu

220 one of these models has proven to be a fully faithful reproduction of the human disease, models remai

221 Such faithful reproduction of the optical clock phase expands

222 mes), and fungal growth on fruits with their faithful reproductions on the nanofiber mats is illustra

223 Faithful resetting of the epigenetic memory of a somatic

224 of the role played by p300 in promoting the faithful resolution of mitotic figures as well as proper

225 quantities of infected brain and demonstrate faithful retention of biological and biochemical strain

226 otif play a vital role in the maintenance of faithful RNA synthesis activity (fidelity) of FMDV 3D(po

227 As clinically-faithful rodent models of sporadic PA are currently unde

228 ntrol mitochondrial movement to ensure their faithful segregation during division.

229 ul DNA replication, chromosome unlinking and faithful segregation into daughter cells.

230 feature of sexual reproduction that ensures faithful segregation of chromosomes and redistributes ge

231 rect chromosome architecture is required for faithful segregation of chromosomes at anaphase I and II

232 Faithful segregation of chromosomes during cell division

233 Faithful segregation of chromosomes to two daughter cell

234 A certain level of this is required for the faithful segregation of chromosomes, but the majority of

235 e is the structural unit responsible for the faithful segregation of chromosomes.

236 The mitotic spindle ensures the faithful segregation of chromosomes.

237 y coordinated events that ultimately lead to faithful segregation of chromosomes.

238 crotubule-based mitotic spindle mediates the faithful segregation of duplicated chromosomes into daug

239 The faithful segregation of duplicated genetic material into

240 The faithful segregation of eukaryotic chromosomes in mitosi

241 generating genetic variation and maintaining faithful segregation of homologous chromosomes during me

242 e Topo2a-dependent arrest is associated with faithful segregation of sister chromatids and has been i

243 re-microtubule attachments are essential for faithful segregation of sister chromatids during mitosis

244 threaten to prevent complete replication and faithful segregation of sister chromatids.

245 is compacted into mitotic chromosomes to aid faithful segregation of the genome between two daughter

246 pindle assembly checkpoint (SAC) ensures the faithful segregation of the genome during mitosis by ens

247 chromosomes during spermatogenesis to ensure faithful segregation post-fertilization.

248 The faithful segregation, or "partition," of many low-copy n

249 2) and ParB-like (omega2) proteins to ensure faithful segregation.

250 ween homologous chromosomes is essential for faithful segregation.

251 ubiquitously, thereby contributing to their faithful segregation.

252 The faithful self-propagation of this fold involves a divers

253 A prerequisite for faithful signal transmission is the positioning and clus

254 blish that sleep deprivation compromises the faithful signaling of, and the "embodied" reciprocity be

255 insertion to its homologous chromosome in a faithful, site-specific manner.

256 redistributes to the spindle pole to ensure faithful spindle architecture.

257 It also aids faithful splicing of pre-mRNAs containing large introns,

258 stablishing different coding strategies: (1) faithful stimulus encoding for generating the VOR; (2) o

259 d model of VOR pathways, we demonstrate that faithful stimulus encoding is necessary to generate the

260 enic for the recombinant BAC appears to be a faithful surrogate for TSLP expression, particularly in

261 g of APs ensures I(Ca) as a tail current and faithful synaptic delay, which is particularly important

262 ve rise to distinct prion strains capable of faithful template-driven propagation.

263 d within the neural code, and supplying more faithful templates to the brain mechanisms subserving ph

264 apse, which is an essential component in the faithful temporal transmission of sound.

265 reconstructions proved to be generally more faithful than those of LICHeE.

266 er this kinase might be suitable to maintain faithful timing and execution of anaphase in the absence

267 nce that vertically transmitted microbes are faithful to a single sponge host species.

268 ithin a single year, females which were more faithful to a specific location had higher reproductive

269 dimension greater than two, while remaining faithful to empirical data on their low-dimensional stru

270 o, convey that they are sharers of knowledge faithful to science's way of knowing and respectful of t

271 ray diffraction shows Mn-SLO is structurally faithful to the native enzyme.

272 show that the resulting implementation stays faithful to the original coding goals while using inhibi

273 , increasing numbers of bumblebees stay more faithful to these flowers, even if they become a subopti

274 ernal structure is fully interpretableand is faithful to underlying chemistry of transcription factor

275 the accelerated kinetics that allow for the faithful tracking of action potentials in neurons.

276 Faithful transcription initiation is critical for accura

277 naptic and postsynaptic contributions to the faithful transfer of information.

278 Faithful translation of mRNA into the corresponding poly

279 a superfamily of enzymes responsible for the faithful translation of the genetic code and have lately

280 tic information from DNA to protein requires faithful translation.

281 he nucleus, where mitosis and meiosis ensure faithful transmission of chromosomes, the mechanisms of

282 observational learning can give rise to the faithful transmission of cultural adaptations.

283 The faithful transmission of DNA methylation patterns throug

284 ity is crucial for cellular survival and the faithful transmission of genetic information.

285 ases after DNA replication, which results in faithful transmission of methylation patterns during cel

286 Faithful transmission of the genetic information is esse

287 repair response in germ cells, which ensures faithful transmission of the genome between generations.

288 hibitory neurons in the MDmc that facilitate faithful transmission to the cortex.

289 e epigenetic elements that were required for faithful transmission to the daughter cell to accurately

290 genetic information accurately to ensure its faithful transmission.

291 ns is impeded by the limited availability of faithful transmitochondrial animal models.

292 We recently showed that a faithful treatment of such nanoscale interfaces requires

293 hich are often a result of screening in less faithful two-dimensional models.

294 a human APC/C-associated E2 that ensures the faithful ubiquitination of cell cycle regulators during

295 mer resolution site) system is essential for faithful vertical genetic transmission, ensuring the res

296 tomography and (68)Ga-NODAGA-RGD PET enabled faithful visualization of PDAC.

297 imensional single cell datasets necessitates faithful visualizations to assess biological populations

298 leotides but also causes the enzyme to favor faithful Watson-Crick base pairing over mutagenic config

299 ale, as this provides a means to distinguish faithful Watson-Crick base-paired DNA from damaged DNA.

300 ns track naturalistic speech in a remarkably faithful way.