ライフサイエンスコーパス: faithfully

1 information can be stored substantially more faithfully.

2 sual cortex (V1) represents the visual world faithfully.

3 s replicated the magnetoencephalography data faithfully.

4 60% of Step it Up components were delivered faithfully.

5 s represent the underlying sample population faithfully.

6 hestrated to duplicate the genome timely and faithfully.

7 satisfied in order for activity to propagate faithfully across layers.

8 m H3K27me3 levels and how the mark transmits faithfully across mammalian somatic cell generations.

9 r-like sequences (PSE_a, PSE_b and VPE) that faithfully activate tissue-specific expression in transg

10 ats were under anesthesia, the C1 cells were faithfully activated by each light pulse up to 40 Hz.

11 preserved in PrP(D) present in urine and are faithfully amplified by means of PMCA; moreover, they su

12 ary structures that can propagate stably and faithfully and cause diseases with specific phenotypic t

13 AMPfret faithfully and dynamically reports the binding of AMP an

14 mers require engineered polymerases that can faithfully and efficiently copy genetic information back

15 DNA polymerases are essential enzymes that faithfully and efficiently replicate genomic information

16 ration, ensuring that genomic information is faithfully and perpetually maintained.

17 experiments confirmed that mitophagy can be faithfully and quantitatively measured in mt-Keima Droso

18 be preserved in the memory engram and can be faithfully and rapidly reinstated during recollection.

19 organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells.

20 discuss how cells exploit this modularity to faithfully assemble NPCs.

21 Furthermore, the algorithm to register faithfully between live and fixed imaging is directly tr

22 nic shapes for GF learning curves, which are faithfully borne out in our experimental data.

23 ur visual field is thought to be represented faithfully by the early visual brain areas; all the info

24 slesion synthesis spectrum and is capable of faithfully bypassing cyclobutane pyrimidine dimer photol

25 yguanosines and UV light-induced DNA damage, faithfully bypassing cyclobutane pyrimidine dimers.

26 gical research is to develop assays that can faithfully capture different types of protein interactio

27 We find that FFPEcap-seq can faithfully capture mRNA expression levels in FFPE specim

28 interactions in the simulations in order to faithfully capture the experimental anisotropy decays, w

29 Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity

30 chers face is how to design experiments that faithfully capture the true range of heterogeneity from

31 tic predisposition to tumor formation can be faithfully captured in stem cell lines is uncertain.

32 ty Kondo model confirms that the Schmidt gap faithfully captures the scaling behaviour by correctly p

33 ary visual cortex (V1) is widely regarded as faithfully conveying the physical properties of visual s

34 at accomplishes the life-sustaining tasks of faithfully decoding mRNA and catalyzing peptide bond for

35 oof of concept, we demonstrate that DGMs can faithfully describe molecular thermodynamics and kinetic

36 that the electrical properties of a cell are faithfully described by a three-element circuit (i.e., t

37 ription, Nur77-eGFP, in which GFP expression faithfully detects Ag encounter by B cells in vitro and

38 MR structure calculation, this allowed us to faithfully determine the symmetry that defines the entir

39 NFL and alphaSyn oligomers in CSF faithfully differentiate early MSA not only from CON but

40 triple bonds of conjugated 1,3-diynes can be faithfully discriminated as long as one of them is propa

41 thus the probability of recruiting DNMT1 to faithfully duplicate the DNA methylation profile.

42 Genetic and epigenetic information are faithfully duplicated and accurately transmitted to daug

43 ery nucleobase within an Okazaki fragment is faithfully duplicated before dissociation but also neces

44 neuromuscular junction (NMJ) is designed to faithfully elicit a muscular contraction in response to

45 However, these can instead be more faithfully emulated by higher-order circuit elements tha

46 namic-range dorsal horn neurons continued to faithfully encode A-nociceptive information, even after

47 ese synapses allowed muscarinic receptors to faithfully encode physiological activity patterns from i

48 Neurons must faithfully encode signals that can vary over many orders

49 h can effectively suppress in-frame PTCs and faithfully encode their cognate amino acid.

50 Lemniscal neurons most faithfully encoded stimuli when the background intensity

51 The auditory pathway faithfully encodes and relays auditory information to th

52 lection of distributed and mobile sensors to faithfully estimate a signal that varies in space and ti

53 oncluded that: (1) patient-derived organoids faithfully express established and newly identified mole

54 A BAC transgenic rats, for which the gene is faithfully expressed, functionally active, and germline

55 rrent response of the complex is expected to faithfully follow even very rapid trains.

56 Instead, we found that ERK signaling faithfully followed RTK dynamics when receptor signaling

57 Moreover, burst stimulation of PPN axons was faithfully followed, even in the presence of NMDAR antag

58 eous strand of tissue, propagation conducted faithfully for lower expression levels but failed comple

59 duals and that this difference is replicated faithfully in MMTV-PyMT and MMTV-Her2 transgenic mouse m

60 ral occipital complex (LOC) represents shape faithfully in such conditions even if the object is part

61 occipital complex (LOC) can represent shape faithfully in such conditions.

62 ii) a thermo-kinetic constitutive model that faithfully includes the atomistic and dislocation scale

63 ssing assay that produces robust signals and faithfully indicates DGCR8 and Drosha activities.

64 ipotent cell culture and demonstrate that it faithfully indicates DNA methylation changes induced upo

65 throughout the mitochondrial network and are faithfully inherited during the cell cycle.

66 In plants, DNA methylation patterns are faithfully inherited over many generations but it is unk

67 ains and their associated structures must be faithfully inherited through cellular division to mainta

68 A dCMP residue was faithfully inserted across the ICL-G by Pol eta, Pol zet

69 nd repressing regulatory influences that are faithfully integrated at the core promoter of individual

70 otopolymerization, the director field can be faithfully "locked," allowing for direct visualization o

71 synaptic responses in mutant fish can follow faithfully low-frequency stimuli despite the reduced amp

72 expression patterns, methods are needed that faithfully maintain long-range exon connectivity informa

73 to promote efficient gene expression and to faithfully maintain silencing of heterochromatin.

74 athological and biochemical differences were faithfully maintained after serial passaging, which impl

75 These patterns are faithfully maintained by DNMT1 during DNA replication to

76 studies elucidate how centromere identity is faithfully maintained despite challenges imposed by DNA

77 omal viral genome and TAg transcription were faithfully maintained in culture and in tumors arising f

78 CWD properties were faithfully maintained in deer following passage through

79 Creutzfeldt-Jakob disease (vCJD) prions are faithfully maintained upon transmission to guinea pigs.

80 complish progenitor cell proliferation while faithfully maintaining genomic integrity and regenerativ

81 ograft (PDX) from an SDH-deficient GIST that faithfully maintains the epigenetics of the parental tum

82 e, the Proteome Integrity Number (PIN), that faithfully measures the degree of protein degradation.

83 lusion, we describe two cellular models that faithfully mimic the acquisition of a treatment induced

84 Fluid mechanical computer simulations faithfully mimic the behavior observed in experiments, s

85 ailability of experimental tumor models that faithfully mimic the progression of human tumors and the

86 tors that allow precise kinetic analysis and faithfully mimic the transition state structurally.

87 ts distinct from the official CASP sets that faithfully mimic their difficulty.

88 ogenesis in translational animal models that faithfully mimic ZIKV infection in humans.

89 The Nyx(nob) mouse model of CSNB1 faithfully mimics this phenotype.

90 TDAs use a database of decoy species to faithfully model score distributions of incorrect peptid

91 dynamic often lack the scale and/or scope to faithfully model the dual and co-dependent nature of thi

92 dapt to neuronal systems and one unlikely to faithfully model the mitochondrial damage that occurs in

93 ogenous MLL oncogenes in primary human HSPCs faithfully models acute MLL-rearranged leukemia and prov

94 Contact hypersensitivity assay (CHS) faithfully models human allergies.

95 To be able to faithfully monitor Gata3 expression noninvasively at the

96 wing, for the first time, to selectively and faithfully monitor the conformations and dynamics of a g

97 Both imaging methods faithfully monitored the biodistribution and elimination

98 The NanoLuc activity faithfully monitored the transcriptional regulation of S

99 ells remain in their present state, which is faithfully passed on through many generations of daughte

100 ormation and chromatin modifications must be faithfully passed on to daughter strands.

101 The model is able to faithfully predict human scoring of facial normality.

102 Transcript levels do not faithfully predict protein levels, due to post-transcrip

103 d mouse models of non-small-cell lung cancer faithfully predict the response of human lung cancers to

104 lain why many animal vaccine trials have not faithfully predicted outcomes in human vaccine trials an

105 Moreover, in addition to faithfully predicting many experimental results recorded

106 etheless, this dynamic transcription profile faithfully predicts the limits of the mature stripe visu

107 Through this pipeline, our approach faithfully predicts the representative structures availa

108 most economical coarse-grained models while faithfully preserving the shape and thus makes normal mo

109 ger be scapegoats for discrepant results but faithfully produce numbers on the material that is asses

110 of how the multiple factors come together to faithfully propagate genomic information.

111 rough seed, enables breeders to identify and faithfully propagate superior heterozygous genotypes by

112 ative to determine the ability of strains to faithfully propagate their structure.

113 The de novo DNAme was faithfully propagated and maintained through cell genera

114 Signatures were faithfully propagated from primaries to matched metastas

115 -like ultrastructural features that could be faithfully propagated over multiple generations.

116 ties give rise to offspring communities that faithfully re-establish parental phenotype.

117 n-component Fermi gas of ultracold atoms can faithfully realize the Hubbard model with readily tunabl

118 large unilamellar vesicle model systems that faithfully recapitulate BAX-dependent mitochondrial oute

119 SMA in humans, the mild type III mice do not faithfully recapitulate chronic SMA variants affecting c

120 n reported, making it unclear which model(s) faithfully recapitulate DUX4 and FSHD biology.

121 cause Dfnb31(wi/wi) and Dfnb31(neo/neo) mice faithfully recapitulate hearing and vision symptoms in p

122 olon-specific inducible mouse model that can faithfully recapitulate human colon cancer initiation an

123 Here, using mouse models that faithfully recapitulate human disease together with orga

124 els of MDS can be genetically engineered and faithfully recapitulate human disease.

125 nt-derived cell lines in studying CA to more faithfully recapitulate in vivo cellular phenotypes.

126 utations, have however remained difficult to faithfully recapitulate in vivo The development of genet

127 at aspects of human AD these mouse AD models faithfully recapitulate is insufficiently understood.

128 Several experimental models faithfully recapitulate many important facets of human m

129 /4 patient induced neuron culture models can faithfully recapitulate molecular signatures seen in APO

130 We find that cell lines faithfully recapitulate oncogenic alterations identified

131 e production of synthetic dHRM datasets that faithfully recapitulate real-world variations arising fr

132 1 (STIM1) to manipulate protein activity and faithfully recapitulate STIM1-mediated signaling events.

133 erative medicine, but most protocols fail to faithfully recapitulate target cell properties.

134 e "gold standard" filovirus model since they faithfully recapitulate the clinical hallmarks of filovi

135 els of malignant rhabdoid tumors (MRTs) that faithfully recapitulate the clinical-pathological featur

136 However, the lack of animal models that faithfully recapitulate the different molecular subtypes

137 models of metabolism at a genome scale that faithfully recapitulate the effect of multiple genetic i

138 The Degron-KI system was able to faithfully recapitulate the effects of pharmacologic EZH

139 ation, possibly using mouse models that more faithfully recapitulate the epidermolysis bullosa simple

140 Patient-derived cell lines faithfully recapitulate the epithelial component of panc

141 -derived microglia-like cells (termed pMGLs) faithfully recapitulate the expected ontogeny and charac

142 ransgenic mice, many of these models fail to faithfully recapitulate the human condition.

143 ble by the development of model systems that faithfully recapitulate the in vivo viral life cycle.

144 cells, suggesting that HepG2-HFL cells more faithfully recapitulate the innate immune response to HC

145 because most in vitro cancer models fail to faithfully recapitulate the local tissue and organ micro

146 overy and advancing existing systems to more faithfully recapitulate the native organ.

147 rch currently lacks in vitro models that can faithfully recapitulate the pathophysiology of the origi

148 Our BC model is the first to faithfully recapitulate the phenotype, cellular and mole

149 ated expression of leukemia-associated genes faithfully recapitulate the spectrum of lymphoproliferat

150 ore, organoids derived from human stem cells faithfully recapitulate the structure and function of hu

151 we used models of the developing brain that faithfully recapitulate the tissue architecture in early

152 t of the cellular state, they may not always faithfully recapitulate the underlying molecular fate.

153 There are no animal models that faithfully recapitulate these infections, and, as such,

154 abetic/severe combined immunodeficiency mice faithfully recapitulated clinical and pathological featu

155 inactivation properties were constructed and faithfully recapitulated conduction abnormalities seen i

156 N and overexpressing ERG (Pten(-/-) R26-ERG) faithfully recapitulated distinct stages of prostate can

157 id-based reporters, transgenic BAC reporters faithfully recapitulated endogenous gene expression patt

158 served in postmortem human LOAD brain can be faithfully recapitulated in the brain of a genetically m

159 gest that previous exogenously tagged Pol II faithfully recapitulated the endogenous polymerase clust

160 The optimal models faithfully recapitulated the ganglion cell outputs.

161 as size in a SRP54-knockdown zebrafish model faithfully recapitulated the human phenotype.

162 er the observed arrangement and architecture faithfully recapitulated the physiologically relevant ri

163 cause resistance to HIV protease inhibitors faithfully recapitulated the reported resistance, sugges

164 was significantly altered in C9-ALS neurons faithfully recapitulated the transcriptional aberrations

165 Using a genetic mouse model that faithfully recapitulates a DISC1 genetic alteration stro

166 There is no animal model that faithfully recapitulates human disease; thus, cultured c

167 This novel mouse model faithfully recapitulates human NPC1 disease and provides

168 ures of known tumor-immune interactions that faithfully recapitulates key features of existing experi

169 alization of ribonucleoprotein complexes and faithfully recapitulates known in vivo determinants for

170 The system faithfully recapitulates mouse inner ear induction follo

171 with an accessible BM microenvironment that faithfully recapitulates normal BM niche morphology and

172 A simple model, which faithfully recapitulates our experimental observations,

173 scribe a yeast SG reconstitution system that faithfully recapitulates SG assembly in response to trig

174 le genotype (MM1 subtype), a sCJD model that faithfully recapitulates the molecular and pathological

175 n of transfection-based CRISPR/Cas9 delivery faithfully recapitulates the stochastic nature of human

176 used a previously established paradigm that faithfully recapitulates this disease in transgenic mice

177 NA-seq) methods, here we show that snRNA-seq faithfully recapitulates transcriptional patterns associ

178 rt a human cell model of valvulogenesis that faithfully recapitulates valve disease in a dish.

179 of brain organoids also have limitations in faithfully recapitulating the in vivo processes.

180 on that leads to the development of tumours, faithfully recapitulating the principal clinical and bio

181 ediated vesicle fusion reaction has not been faithfully reconstituted in biochemical assays.

182 tigated its biosynthesis in living cells and faithfully reconstituted the underlying processes in vit

183 ng to difficulties in phasing short reads to faithfully recover the original strain-level genotypes,

184 observed in fluorescence, we show that QRBF faithfully recovers shape and enables quantify size of i

185 filters and the basic PF are more capable of faithfully recreating historical influenza incidence tim

186 esents an important step on the road towards faithfully recreating these diseases in vitro.

187 odels mimicking chronic HBV infection do not faithfully reflect disease progression in humans.

188 In this study, we show that GATIR mice faithfully reflect endogenous Gata3 expression without d

189 nces in modeling drug absorption, which more faithfully reflect human intestinal physiology and reduc

190 They also faithfully reflect problems that associated with the his

191 , suggesting a need for Pol V transcripts to faithfully reflect the DNA sequence of target loci to wh

192 We found that the molecular data faithfully reflect the morphology-based indices and prov

193 how that the midbrain evoked potential (mEP) faithfully reflects the temporal and spatial structure o

194 nce contrary to adult mammals, it is able to faithfully regenerate cardiac tissue.

195 Zebrafish can faithfully regenerate injured fins through the formation

196 o developed a correlation-based algorithm to faithfully register live and FISH images.

197 ation and transcription rely on chromatin to faithfully regulate DNA accessibility, yet how chromatin

198 y link homologous DNA strands and have to be faithfully removed for proper DNA segregation and genome

199 ates nonimmunoglobulin genes, and failure to faithfully repair these off-target lesions can cause B c

200 Unless efficiently and faithfully repaired, DNA double-strand breaks (DSBs) cau

201 The eukaryotic replisome must faithfully replicate DNA and cope with replication fork

202 e able to use the unnatural triphosphates to faithfully replicate DNA containing the UBP within the c

203 s, which are ordered protein assemblies that faithfully replicate in vivo and cause specific biologic

204 impeded by the lack of screening models that faithfully replicate prion diseases and the lack of rapi

205 Current reconstitutions have yet to faithfully replicate the fusion process in at least thre

206 x mineralization, subclones 14 and 24 do not faithfully replicate these key aspects of osteoblast bio

207 netic information encoded in genomes must be faithfully replicated and transmitted to daughter cells.

208 Eukaryotic chromosomal DNA is faithfully replicated in a complex series of cell-cycle-

209 s way, the facets on the initial Pd seed are faithfully replicated in the resultant Pd@Ir core-shell

210 iosis, the hallmark of gametogenesis, can be faithfully replicated outside of the gonad.

211 differentiated into functional subsets that faithfully replicated those seen in wild-type mice.

212 The reported assay system faithfully replicates the pharmacology of the receptor i

213 patients with nonalcoholic steatohepatitis, faithfully replicating another key benefit of bariatric

214 sted the hypothesis that hemodynamic signals faithfully report neural activity during voluntary behav

215 which different mammalian transgene methods faithfully report on the properties of endogenous protei

216 fluorescence intensities was demonstrated to faithfully report the fraction of FAP-EGFR located in ac

217 PET imaging using (64)Cu-Macrin faithfully reported accumulation of macrophages in the h

218 ches involved neuromuscular transmission and faithfully reported muscle force generation.

219 Indeed, XY-69 faithfully reported the membrane-dependent activation of

220 controls, we demonstrate that the cell line faithfully reports changes in type I collagen expression

221 ctivity by analysis of individual nuclei and faithfully reports ERK activity during development and n

222 Here, we investigate the extent to which fUS faithfully reports local neuronal activation by combinin

223 Additionally, VF2.1(OMe).H faithfully reports pharmacological effects and circuit a

224 FlicR1 faithfully reports single action potentials ( approximat

225 fish transgenic line, Tg(igfbp5a:GFP), which faithfully reports the mitotic action of IGF1R-PI3K-Akt-

226 onfirm that our computationally derived RDIs faithfully represent a measure of Ras dependency in both

227 rly when paired with in vivo tumor data that faithfully represent all stages of disease progression.

228 Canine simple carcinomas, which faithfully represent human breast carcinomas at the mole

229 elective fMRI patterns in motor system areas faithfully represent movement direction regardless of vi

230 , presents considerable challenges in how to faithfully represent N limitation.

231 These 3D microtumor models faithfully represent size-induced microenvironmental cha

232 , while fMRI patterns in visual system areas faithfully represent target location regardless of movem

233 Populations of MPC cells faithfully represent the elapsed time between taps, and

234 ly sensitive neurons, such as grid cells, to faithfully represent the environment these circuits requ

235 cancer model system, as they are presumed to faithfully represent the genomic features of primary tum

236 e scarce and measured in vitro, thus may not faithfully represent the in vivo situation.

237 at the varied single-cell patterns add up to faithfully represent TRAs, is poorly understood.

238 , the unattended background streams are more faithfully represented as a single unsegregated backgrou

239 fects of miRNA on endogenous genes cannot be faithfully represented by reporter systems in which, at

240 whiten naturalistic self-motion but instead faithfully represented the stimulus' detailed time cours

241 large-scale and whether integrated reporter faithfully represents target biology.

242 Our SOMA faithfully represents the tissue-based molecular assay i

243 n constrain spontaneous pattern formation to faithfully reproduce functional maps in subsequent brain

244 dology to generate structural ensembles that faithfully reproduce HDX-MS measurements.

245 MDNs have the potential to faithfully reproduce multiple outputs of an individual-b

246 the N terminus (GAP43-CFP-Galphai/o) seem to faithfully reproduce the behavior of the non-modified Ga

247 The model simulations faithfully reproduce the clinical cohort at three levels

248 onstration of efficacy in animal models that faithfully reproduce the human condition.

249 ctional studies in mouse organ cultures that faithfully reproduce the initiation of prostate developm

250 Our methods faithfully reproduce the low energy spectrum of the targ

251 rities in the original branching pattern are faithfully reproduced after regeneration, suggesting tha

252 iophysical activation properties, which were faithfully reproduced by an allosteric channel gating sc

253 tivation and deactivation kinetics, which we faithfully reproduced by an allosteric channel gating sc

254 The model faithfully reproduced differences in stomatal closure as

255 thm optimising accuracy/complexity measures, faithfully reproduced experimental data and predicted th

256 e chromatin as a plastic material, our model faithfully reproduced the experimentally observed irreve

257 -mer minicircle DNA using the same TG-motifs faithfully reproduces the CPD pattern in the nucleosome,

258 We show that OnGuard2 faithfully reproduces the kinetics of stomatal conductan

259 AITC-like), and provide a kinetic model that faithfully reproduces their differential effects.

260 The model faithfully reproduces typical cell shapes and movements

261 This model faithfully reproduces wildtype and mutant behaviors by s

262 nefficient and that ER tubules were dilated, faithfully reproducing the cellular phenotype of individ

263 neration and growth of ectopic malformations faithfully resembling human odontoma.

264 n and electroporation of recombinant Spindly faithfully resulted in robust kinetochore localization.

265 The lines thus derived faithfully retained their parental cystic and spiky morp

266 urately reflect the muscle transcriptome and faithfully reveal disease-causing mutations.

267 esis, where dynamic microtubules capture and faithfully segregate chromosomes into daughter cells.

268 (CIN), the persistent inability of a cell to faithfully segregate its genome, is a feature of many ca

269 During mitosis, sister chromatids must be faithfully segregated to ensure that daughter cells rece

270 These dynamic changes in cluster pattern are faithfully simulated by a mathematical model of a Turing

271 and reconstructs dynamics of DNA replication faithfully starting both from population-wide data and d

272 pproximately 2-4 Hz) were reconstructed more faithfully than other temporal modulations.

273 cally relevant cortical pathophysiology more faithfully than previously thought.

274 valuate novel therapies or vaccines, but how faithfully they recapitulate the biology of human melioi

275 e integration and were able to fire APs more faithfully to repeated odor stimuli.

276 is essential to transmit genetic information faithfully to the next generation.

277 The network faithfully traces routes of infections for documented co

278 r approximately 15 mV, inhibition of spiking faithfully tracking chloride gradients and intrinsic cel

279 We show that this reporter faithfully tracks somatic calcium dynamics in the mouse

280 ranscriptases with two priming techniques to faithfully transcribe 16S rRNA and amoA transcripts from

281 c partners, which requires axons not only to faithfully transfer action potentials to distant synapti

282 playing frequency-invariant transmission can faithfully transfer ongoing presynaptic rates enabling l

283 Globular bushy cells reliably and faithfully transfer spike signals to the principal neuro

284 n sleep would require that waking events are faithfully transferred to and reproduced in sleep.

285 Purkinje cell dendrites faithfully transformed this climbing fiber activity into

286 cause neither of its constituent nucleobases faithfully transmit genetic information from the origina

287 For species survival, the germline must faithfully transmit genetic information to the progeny.

288 ormers, vary in their ability to acquire and faithfully transmit music.

289 rent strains, namely VK and VL, and shown to faithfully transmit specific strain characteristics to y

290 use meiosis to generate haploid gametes and faithfully transmit their genome to the next generation.

291 naptic noise and allows rod bipolar cells to faithfully transmit upstream signal and noise to downstr

292 ajority of genic CG methylation patterns are faithfully transmitted over nine generations according t

293 mbionts improve host fitness, they should be faithfully transmitted to offspring.

294 e intron within the UBC promoter fragment is faithfully transmitted to target cells.

295 However, whether this information can be faithfully transmitted to the gene expression level is u

296 ed a process by which broken chromosomes are faithfully transmitted via the BubR1-dependent tethering

297 ng of genes during mitosis is a mechanism of faithfully transmitting cell-specific transcription patt

298 ve states has been the lack of crystals that faithfully undergo this transition within the crystal la

299 t changes allow cells to round up and divide faithfully when confined underneath a stiff hydrogel, co

300 thod that overcomes the unusual cell wall to faithfully yield the full spectrum of non-coding RNA (nc