ライフサイエンスコーパス: familial hemiplegic migraine

1 we identified a novel PNKD gene deletion in familial hemiplegic migraine.

2 ated disorders is much broader than strictly familial hemiplegic migraine.

3 umber of human neurologic diseases including familial hemiplegic migraine.

4 7) severe myoclonic epilepsy of infancy, and familial hemiplegic migraine.

5 dies, and linkage and association studies of familial hemiplegic migraine.

6 Familial hemiplegic migraine, a rare Mendelian form of M

7 had episodic ataxia and one PNKD family had familial hemiplegic migraine alone.

8 Studies of linkage between familial hemiplegic migraine and marker 19p13 in 13 exte

9 ly engineered to provide an understanding of familial hemiplegic migraine and possibly, by extrapolat

10 KA) alpha-subunit, have been associated with familial hemiplegic migraine (ATP1A2), alternating hemip

11 ons of the ion pump alpha2-Na/K ATPase cause familial hemiplegic migraine, but the mechanisms by whic

12 The recent discovery that familial hemiplegic migraine, episodic ataxia type 2, an

13 onal P/Q-type voltage-gated calcium channel (familial hemiplegic migraine, episodic ataxia type 2, sp

14 to cause such human neurological diseases as familial hemiplegic migraine, episodic ataxia-2, and spi

15 ame calcium channel gene are associated with familial hemiplegic migraine, episodic or progressive at

16 s to the genetic susceptibility of both rare familial hemiplegic migraine (FHM) and more common types

17 ldhood (AHC) is typically distinguished from familial hemiplegic migraine (FHM) by infantile onset of

18 Familial hemiplegic migraine (FHM) has been related to m

19 Familial hemiplegic migraine (FHM) is a rare subtype of

20 Familial hemiplegic migraine (FHM) is an autosomal domin

21 Familial hemiplegic migraine (FHM) is an autosomal domin

22 ive and memory difficulties observed in some familial hemiplegic migraine (FHM) patients, we examined

23 at intracortical synapses in mouse models of familial hemiplegic migraine (FHM) suggested the hypothe

24 ing interneurons (FS INs) in mouse models of familial hemiplegic migraine (FHM) suggested the hypothe

25 Familial hemiplegic migraine (FHM), a migraine subtype t

26 2, and within a candidate region at 1q23 for familial hemiplegic migraine (FHM).

27 linked to several human diseases, including familial hemiplegic migraine (FHM).

28 Familial hemiplegic migraine is an episodic neurological

29 Familial hemiplegic migraine is associated with at least

30 Familial hemiplegic migraine is caused by mutations in t

31 Familial hemiplegic migraine knock-in mice expressing th

32 n tissues and has previously been related to familial hemiplegic migraine (MIM#602481) and alternatin

33 g and synaptic transmission resulting from a familial hemiplegic migraine mutation (S218L).

34 Two PRRT2 mutations were in familial hemiplegic migraine or episodic ataxia, one SLC

35 Familial hemiplegic migraine type 1 (FHM1) arises from m

36 Familial hemiplegic migraine type 1 (FHM1) is a subtype

37 Familial hemiplegic migraine type 1 (FHM1) is an autosom

38 Patients suffering from familial hemiplegic migraine type 1 (FHM1) may have a di

39 Familial hemiplegic migraine type 1 (FHM1), a monogenic

40 e-gated CaV2.1 channels, are associated with familial hemiplegic migraine type 1 (FHM1), a rare monog

41 Familial hemiplegic migraine type 1 (FHM1), a severe mig

42 rare, dominant form of this common disease, familial hemiplegic migraine type 1 (FHM1), arises from

43 g alpha1A mutations that are associated with familial hemiplegic migraine type 1 (FHM1).

44 c voltage-gated calcium channels can lead to familial hemiplegic migraine type 1 (FHM1).

45 wn to cause Episodic Ataxia type 2 (EA2) and Familial Hemiplegic Migraine type 1 (FHM1).

46 arry a mutation analogous to the one causing familial hemiplegic migraine type 1 in humans, showed ma

47 In familial hemiplegic migraine type 1 mice, olcegepant 1mg

48 In familial hemiplegic migraine type 1 mutant mice expressi

49 opagated into subcortical structures in both familial hemiplegic migraine type 1 mutants.

50 ng depolarization in mice carrying the human familial hemiplegic migraine type 1 R192Q missense mutat

51 Familial hemiplegic migraine type 1, a monogenic migrain

52 euron, Tottene et al. study a mouse model of familial hemiplegic migraine type 1, and provide evidenc

53 glycerin (NTG)-induced rat migraine model, a familial hemiplegic migraine type 2 (FHM2) mouse model,

54 imaging, we show that awake mice carrying a familial hemiplegic migraine type 2 (FHM2) mutation have

55 The neurological disorders familial hemiplegic migraine type 2 (FHM2), alternating

56 s lead to severe human pathologies including Familial Hemiplegic Migraine type 2, Alternating Hemiple

57 Familial hemiplegic migraine type 3 (FHM3) is a severe a

58 ere monogenic subtype of migraine with aura, familial hemiplegic migraine type 3 (FHM3).

59 SCN1A(L263V) missense mutation, which causes familial hemiplegic migraine type 3 in heterozygous fami

60 itude consistent with mild gain of function, familial hemiplegic migraine type 3 variants induce a la

61 Functional studies of both epilepsy and familial hemiplegic migraine type 3 variants reveal alte

62 Findings were related to Dravet syndrome and familial hemiplegic migraine type 3 variants.

63 echanisms between SCN1A-related epilepsy and familial hemiplegic migraine type 3, and identifies sodi

64 function SCN1A variants are associated with familial hemiplegic migraine type 3.

65 The neurological disorder familial hemiplegic migraine type II (FHM2) is caused by

66 isoforms (rapid-onset dystonia parkinsonism, familial hemiplegic migraine type-2), as well as reducti

67 f-function mutations of NaV1.1 (SCN1A) cause familial hemiplegic migraine type-3 (FHM3), a subtype of