ライフサイエンスコーパス: fatal

1 e cause of disability worldwide and is often fatal.

2 n anorexia-cachexia syndrome, which is often fatal.

3 curative, with the condition being uniformly fatal.

4 follow-up; neither of these recurrences was fatal.

5 g the first years of life can be potentially fatal.

6 and 31% of patients, respectively; none were fatal.

7 was 60%; in contrast, 95% of ST16 cases were fatal.

8 ortion of patients the disease is severe and fatal.

9 ephalus, and is almost invariably prenatally fatal.

10 ction have been reported, of which ~60% were fatal.

11 llow-up of 18.6 y, 121 (18.9%) of which were fatal.

12 sulting pathologies are often deleterious or fatal.

13 mote the development of epilepsy, and can be fatal.

14 stance-use outcomes among men and women, and fatal accidents and violence among men, might be causall

15 used biologic therapies to avert potentially fatal acute respiratory distress syndrome and treat hype

16 There were no fatal adverse events.

17 rehospitalization for heart failure and non-fatal AMI at 12-months in ST-segment elevation myocardia

18 lty in accurately ascertaining the causes of fatal anaphylaxis and therefore in assigning the proper

19 Epidemiological data on fatal anaphylaxis are underestimated worldwide.

20 Although very rare, fatal anaphylaxis during in-hospital food challenge has

21 Definite fatal anaphylaxis was mostly due to the use of medicatio

22 We did not find any data on food fatal anaphylaxis.

23 These diseases are always fatal and have long asymptomatic incubation periods.

24 Idiopathic pulmonary fibrosis (IPF) is a fatal and incurable form of interstitial lung disease in

25 ty of idiopathic pulmonary fibrosis (IPF), a fatal and irreversible interstitial lung disease, is pre

26 iffuse intrinsic pontine gliomas (DIPGs) are fatal and lack treatments.

27 aggressive malignancy that is almost always fatal and lacks effective systemic treatment options for

28 ill patients resulted in a 28% reduction in fatal and major thromboembolic events without a signific

29 aban reduces the risk of venous and arterial fatal and major thromboembolic events without significan

30 acutely ill medical patients are at risk for fatal and major thromboembolic events.

31 The key outcomes were the incidence of fatal and non-fatal cardiovascular diseases, cancers, in

32 ed to clinic BP in predicting the subsequent fatal and non-fatal cardiovascular/renal disease events

33 o estimate the effect of SGLT2 inhibition on fatal and non-fatal heart failure events and renal outco

34 All incidences of fatal and non-fatal stroke during the study period were

35 Fatal and nonfatal cases were compared.

36 lts from the same cohort, as well as between fatal and nonfatal cases.

37 edictive capabilities of scoring systems for fatal and nonfatal liver disease, determine which scorin

38 in SOT recipients may disseminate and become fatal, and although only few cases of VZV infection were

39 Prion disease is a rare, fatal, and exceptionally rapid neurodegenerative disease

40 onary arterial hypertension (PAH) is a rare, fatal, and incurable disorder.

41 Malignant glioma is rapidly fatal, and ionizing radiation is part of the current sta

42 produced a hierarchically organized, rapidly fatal, and serially transplantable blast population, phe

43 on channel function and this may precipitate fatal arrhythmia in utero.

44 %) individuals had experienced a potentially fatal arrhythmic event with a median age of onset of 7 y

45 Fatal asthma cases are hallmarked by poorly steroid-sens

46 n immune tolerance, as their loss leads to a fatal autoimmune syndrome in mice and humans.

47 We found that expression of OVA resulted in fatal autoimmunity and in prevention of peripheral Treg

48 Brg1 impairs Treg cell activation and causes fatal autoimmunity in mice.

49 Biallelic deficiency precipitated fatal autoimmunity with intense autoantibody production

50 into a concerning clinical pathogen, causing fatal bacteremia.

51 nd its human host susceptible to potentially fatal Bcc superinfection.

52 leeding components of the NCB, in particular fatal bleeding (0.09%/y versus 0.06%/y; hazard ratio, 1.

53 s, with accompanying fluid egress, may cause fatal brain swelling.

54 symptoms in early childhood and typically is fatal by 20-30 years of life(4-7).

55 noma (ESCC) is among the most aggressive and fatal cancer types.

56 before middle age for preventing this highly fatal cancer.

57 ins one of the most treatment refractory and fatal cancers.

58 econd, model the level of risk of developing fatal carcinogenesis; and third, test whether pattern of

59 film (with known cardiac risk factors) had a fatal cardiac arrest.

60 unction and microcytic anemia, while one had fatal cardiomyopathy with lactic acidosis following a fe

61 outcomes were the incidence of fatal and non-fatal cardiovascular diseases, cancers, injuries, respir

62 P in predicting the subsequent fatal and non-fatal cardiovascular/renal disease events in AA subjects

63 rs, 50 subjects had one or more fatal or non-fatal cardiovascular/renal disease events.

64 Half the patients with fatal cases (25 of 54 [46%]) were seen in an outpatient

65 68 fatal cases had CHIKV infection confirmed by RT-qPCR (52

66 Fatal cases had features of relative hypovolemia and red

67 A total of 26 of 50 patients (52%) with fatal cases had obesity.

68 Fatal cases had smaller baseline LVIDd and LVIDs indices

69 ective study was to correlate CT patterns of fatal cases of coronavirus disease 2019 (COVID-19) with

70 ompared the characteristics of patients with fatal cases of EVALI with those of patients with nonfata

71 ntation of the histopathological features in fatal cases of the disease caused by SARS-CoV-2 (COVID-1

72 l history, a higher proportion of those with fatal cases than those with nonfatal cases had a history

73 The median age for fatal cases was 33 months (interquartile range, 12-72) a

74 The proportion of patients with fatal cases was higher among those 35 years of age or ol

75 In fatal cases, quantitative ADC histogram analyses also de

76 tion of CHIKV with DENV were found in 22% of fatal cases, ZIKV in 2.9%, and DENV and ZIKV in 1.5%.

77 es in ciliated bronchial epithelial cells of fatal cases.

78 dies display severe neurotoxicity, including fatal cerebral edema associated with T cell infiltration

79 ysis included myocardial infarction (MI) and fatal CHD.

80 cytokine storm syndrome (CSS), a potentially fatal complication of chronic rheumatic diseases.

81 ceal bleeding is a worrisome and potentially fatal complication of cirrhosis, primary prophylaxis has

82 cal cord paralysis is a rare but potentially fatal complication of proximal esophagus stenting.

83 ly regarded as a safe procedure, potentially fatal complications can occur.

84 hypo/hyperglycemic episodes associated with fatal complications in type-1 diabetes patients.

85 brain-heart interactions are not limited to fatal complications.

86 to rise, heat-related illness, a potentially fatal condition in dogs, will become an ever-greater thr

87 (IgE)-mediated anaphylaxis is a potentially fatal condition in which allergy effector cells rapidly

88 following beta-cell failure, a historically fatal condition now sustainable only by administration o

89 ford progeria syndrome (HGPS) is a uniformly fatal condition that is especially prevalent in skin, ca

90 amyloidosis is an insidious and potentially fatal condition.

91 monary embolism, is a common and potentially fatal condition.

92 The potentially fatal consequence of food allergies makes managing them

93 1 antibodies, can lead to fulminant and even fatal consequences and thus require early detection and

94 mislocalization of glycosomal enzymes, with fatal consequences for the parasite.

95 cation of diabetes mellitus with potentially fatal consequences, is characterized by hyperglycemia an

96 ection or rupture with devastating and often fatal consequences.

97 , it is rejected by this process, often with fatal consequences.

98 HD events (including myocardial infarctions, fatal coronary events, silent infarctions, revasculariza

99 isease risk (acute myocardial infarction and fatal coronary heart disease).

100 itors) or among patients who had a severe or fatal course of the disease (adjusted odds ratio, 0.83 [

101 In fatal Covid-19, lungs at autopsy have been filled with a

102 ied safety outcomes included major bleeding (fatal, critical, or clinically overt bleeding or bleedin

103 , 95% confidence interval (CI): 1.06, 1.75), fatal CVD (HR = 2.05, 95% CI: 1.42, 2.97), and nonfatal

104 e total effect of PA on all-cause mortality, fatal CVD, and nonfatal CVD events, respectively.

105 ations of PA level with all-cause mortality, fatal CVD, and nonfatal CVD events.

106 utcome, major adverse cardiovascular events, fatal CVD, myocardial infarction, and stroke.

107 Lymphangioleiomyomatosis (LAM) is a rare fatal cystic lung disease due to bi-allelic inactivating

108 ntact proviruses, defined by a lack of overt fatal defects such as large deletions and APOBEC3G-media

109 multifocal leukoencephalopathy (PML), an oft-fatal demyelinating brain disease in individuals receivi

110 e population and is the causative agent of a fatal demyelinating disease of the central nervous syste

111 ocin-induced pancreatic islet disruption and fatal diabetes, we found that peripheral implantation of

112 Sleeping sickness is a fatal disease caused by the protozoan parasite Trypanoso

113 teral sclerosis is a rapidly progressing and fatal disease characterized by muscular atrophy due to l

114 Pulmonary arterial hypertension (PAH) is a fatal disease characterized by profound vascular remodel

115 , a relentlessly progressive and universally fatal disease characterized by the degeneration of upper

116 demic in domestic birds can cause severe and fatal disease even in healthy individuals.

117 etiologic agent of tularemia, a potentially fatal disease if untreated.

118 virus capable of causing severe, potentially fatal disease in humans in the 21(st) century.

119 ich spreads systemically and caused a rapid, fatal disease in pups.

120 Idiopathic pulmonary fibrosis is a fatal disease involving destruction of the lung alveolar

121 Amyotrophic lateral sclerosis (ALS) is a fatal disease involving motor neuron degeneration.

122 Idiopathic pulmonary fibrosis (IPF) is a fatal disease of unknown cause that is characterized by

123 ic pulmonary fibrosis (IPF) is a chronic and fatal disease of unknown etiology; however, apoptosis of

124 IGNIFICANCE STATEMENT Sleeping sickness is a fatal disease that disrupts the circadian clock, causes

125 ex - L. donovani and L. infantum - cause the fatal disease visceral leishmaniasis.

126 e that RAG2 knockout hamsters develop severe/fatal disease when exposed to SARS-CoV-2.

127 ogenies in ten prostate cancer patients with fatal disease, and investigate them in conjunction with

128 Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the selective loss of mo

129 most of the population but can cause a rare, fatal disease, progressive multifocal leukoencephalopath

130 affected and experience progressive or even fatal disease.

131 f their mammalian host, leading to severe or fatal disease.

132 ernumerary copy variants, lead to severe and fatal disease.

133 nd Machupo virus (MACV) can cause severe and fatal diseases in humans.

134 pathway, aberration of which often leads to fatal diseases, including cancers.

135 Current management of AKI, a potentially fatal disorder that can also initiate or exacerbate CKD,

136 covery, CN1 remains a morbid and potentially fatal disorder.

137 Increases in fatal drug poisonings and hepatitis C infections associa

138 athogenic zoonotic paramyxovirus that causes fatal encephalitis and respiratory disease in humans.

139 The number of diagnosed fatal encephalitis cases in humans caused by the classic

140 Rabies, caused by rabies virus (RABV), is a fatal encephalitis in humans and other mammals, which co

141 Rabies virus (RABV) causes fatal encephalitis in more than 59,000 people yearly.

142 c virus that causes near-annual outbreaks of fatal encephalitis in South Asia-one of the most populou

143 ange from acute fever and fatigue to chronic fatal endocarditis.

144 leading to neurodegeneration and intractable fatal epilepsy.

145 ng state, the course of the disease is often fatal, especially in immunocompromised individuals, as r

146 tions to peanut are the most common cause of fatal food-related anaphylaxis.

147 fined to their localized areas, rarely prove fatal for device performance, and are largely not respon

148 ans, where a defect in this process might be fatal for embryo development.

149 genesis (BRA) represents the most severe and fatal form of CAKUT.

150 Lafora disease (LD) is a genetic and fatal form of neurodegenerative disorder characterized b

151 ice lacking SHP2 in Osx(+) cells developed a fatal GI pathology with dramatic villus hypoplasia.

152 g severe and disabling, life-threatening, or fatal (grade 3-5) health conditions than siblings of the

153 DLTs occurred, including 2 irAEs and 2 with fatal GVHD.

154 igh grade serous ovarian cancer (HGSOC) is a fatal gynecologic malignancy in the U.S. with limited tr

155 lococcus aureus pose a serious and sometimes fatal health issue.

156 identify cancer patients at highest risk of fatal heart disease compared to the general population a

157 For almost all cancer survivors, the risk of fatal heart disease increases with time.

158 nd the standardized mortality ratio (SMR) of fatal heart disease is 2.24 (95% CI: 2.23-2.25).

159 can, and unmarried are at a greatest risk of fatal heart disease.

160 effect of SGLT2 inhibition on fatal and non-fatal heart failure events and renal outcomes in all ran

161 ew World mammarenaviruses (NWMs) that causes fatal hemorrhagic disease in humans and is the etiologic

162 ople annually and has the potential to cause fatal hemorrhagic fever and shock.

163 Menkes is an infantile, fatal, hereditary copper-deficiency disorder that is cha

164 t Prf1-/- mice develop prolonged viremia and fatal HLH.

165 r virus, which is responsible for severe and fatal human disease.

166 ngo hemorrhagic fever virus, responsible for fatal human disease.

167 Ureaplasma species (spp) has been linked to fatal hyperammonemia syndrome (HS) in lung transplant re

168 hat causes African trypanosomiasis, which is fatal if left untreated.

169 The disease is considered fatal if left untreated.

170 luding anaphylaxis, a severe and potentially fatal IgE-dependent immediate hypersensitivity reaction

171 ildren and determine risk factors for RF and fatal illness in a vulnerable population.

172 nduced thrombocytopenia (HIT), a potentially fatal immune disorder affecting 1-5% of patients receivi

173 The fatal impact of bleeding and MI persisted beyond one yea

174 d with SARS-CoV-2 and that the infection was fatal in 0.3%.

175 re a rare cause of nemaline myopathy that is fatal in infancy due to respiratory insufficiency.

176 infection in the human population and can be fatal in neonatal and immunocompromised individuals.

177 on and causes lifelong infection that can be fatal in neonatal and immunocompromised individuals.

178 smosis, a debilitating infection that can be fatal in the immunocompromised.

179 2%, respectively; and drug-related AEs (none fatal) in 11.7% and 9.7%, respectively.

180 rs increased with the number of SDH for both fatal incident CHD (0 SDH, 1.30; 1 SDH, 1.44; 2 SDH, 2.0

181 , crude and fully adjusted hazard ratios for fatal incident CHD among those with >=3 SDH were 3.00 (9

182 Outcomes were expert adjudicated fatal incident CHD and nonfatal MI.

183 r magnitude and independent associations for fatal incident CHD.

184 s were associated with nonfatal MI than with fatal incident CHD.

185 means of NO2 and NOx, with both overall and fatal incident MI.

186 Yet, their use in preventing fatal infection caused by foodborne Listeria monocytogen

187 species specific.IMPORTANCE The magnitude of fatal infections caused by all different viruses in huma

188 bo group, with eight (4%) treatment-emergent fatal infections reported in the venetoclax group and no

189 induced disease, developing severe and often fatal infectious mononucleosis, hemophagocytic lymphohis

190 Prion diseases are fatal infectious neurodegenerative disorders in human an

191 matic in low resource environments where non-fatal injuries can lead to high morbidity rates, prolong

192 Although GSW is a more morbid and often fatal injury, the general principles of selective conser

193 At-risk individuals can develop often fatal invasive disease for which therapeutic options are

194 coronary events (myocardial infarction plus fatal ischemic heart disease), 8849 and 10,922 ischemic

195 However, severe and fatal LF cases were characterized by poor LASV-specific

196 associated with respiratory failure (RF) and fatal lower respiratory tract infection (LRTI) in premat

197 ed the therapeutic potential of IL-4 against fatal malaria in Plasmodium berghei ANKA-infected C57BL/

198 smoplastic small round cell tumor (DSRCT), a fatal malignancy occurring primarily in adolescent/young

199 s a global human fungal pathogen that causes fatal meningoencephalitis in mostly immunocompromised in

200 In Model 1 for incident fatal MI, we observed a strong association with a 3-y ru

201 ositive associations for PM2.5 and PM10 with fatal MI.

202 s strategies to avoid costly and potentially fatal misdiagnoses.

203 a dominant-negative mechanism to cause this fatal mitochondrial disorder.

204 temic symptoms (DiHS/DRESS) is a potentially fatal multiorgan inflammatory disease associated with he

205 ngenital muscular dystrophy (LAMA2-CMD) is a fatal muscle disease caused by mutations in the LAMA2 ge

206 Duchenne muscular dystrophy (DMD) is a fatal muscle disorder characterized by cycles of degener

207 rvention (HR, 0.78 [95% CI, 0.63-0.95]), and fatal myocardial infarction (HR, 0.50 [95% CI, 0.26-0.97

208 of all-cause death, non-fatal stroke, or non-fatal myocardial infarction) in patients receiving PCI o

209 Fatal, natural anthrax infections transmit the bacterium

210 Huntington's Disease (HD) is a progressive, fatal neurodegenerative condition.

211 Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motoneurons (M

212 Huntington disease (HD) is a fatal neurodegenerative disease caused by a pathogenic e

213 Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by abnormal expan

214 Niemann-Pick type C (NPC) disease is a fatal neurodegenerative disorder caused by mutations in

215 Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder caused by the loss of m

216 has emerged as a robust fluid biomarker for fatal neurodegenerative disorders like amyotrophic later

217 prion diseases are rare and usually rapidly fatal neurodegenerative disorders, the most common being

218 substrates and onset of the progressive and fatal neurodegenerative lysosomal storage disease, GM1 g

219 er-prone xeroderma pigmentosum (XP-G) or the fatal neurodevelopmental disorder Cockayne syndrome (XP-

220 tions present as a severe systemic and often fatal neurologic and/or respiratory disease.

221 esents mild to severe disease, and sometimes fatal neurological and respiratory manifestations.

222 Rabies virus (RABV) causes a severe and fatal neurological disease, but morbidity is vaccine pre

223 Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease caused by deleterious mutati

224 Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease characterized by motor neuro

225 ry outcome was a composite of CVEs including fatal/nonfatal ischemic stroke and myocardial infarction

226 14 +/- 4 years, 50 subjects had one or more fatal or non-fatal cardiovascular/renal disease events.

227 Analyses included all the patients with fatal or nonfatal cases of EVALI that were reported to t

228 Most of the patients with fatal or nonfatal cases of EVALI were male (32 of 60 [53

229 The proportion of patients with fatal or nonfatal cases was higher among those who were

230 d the association between the future risk of fatal or nonfatal myocardial infarction and low-attenuat

231 Fatal or nonfatal myocardial infarction occurred only in

232 computed tomography and were followed up for fatal or nonfatal myocardial infarction over 42 months (

233 provides powerful independent prediction of fatal or nonfatal myocardial infarction.

234 ) were all higher in the 41 patients who had fatal or nonfatal myocardial infarction.

235 plaque burden is the strongest predictor of fatal or nonfatal myocardial infarction.

236 ozin to prevent 1 experiencing an episode of fatal or nonfatal worsening was 16.

237 humans, Nipah virus (NiV) continues to cause fatal outbreaks of encephalitis and respiratory disease

238 d showed high accuracy for the prediction of fatal outcome (area under the curve 0.94).

239 is between ST/CC groups and risk factors for fatal outcome (logistic regression) were evaluated.

240 in-2 and microRNA-150, was associated with a fatal outcome in adults.

241 Conversely, fatal outcome in AGMs was associated with aberrant innat

242 mor mass have a more aggressive course and a fatal outcome risk.

243 P < .001) were independent risk factors for fatal outcome.

244 nd pharyngeal specimens were associated with fatal outcome.

245 he respiratory tract, to severe disease with fatal outcome.

246 disease (EVD), with high values leading to a fatal outcome.

247 or the number of deaths from each of the 282 fatal outcomes included in the GBD 2017 list of causes,

248 Fatal outcomes were associated with irreversible multipl

249 , have been reported to have higher risks of fatal outcomes, associated with higher parasite biomass

250 n posture during acute reactions can trigger fatal outcomes, but the impact of allergic reactions on

251 en a CAD PRS and incident cardiovascular and fatal outcomes.

252 ogy and dysregulation, which likely leads to fatal outcomes.

253 e and the specific pathogens associated with fatal outcomes.

254 des may be important particularly in rapidly fatal ovarian tumors.

255 een declared a public health emergency, with fatal overdoses following relapse reaching epidemic prop

256 Botulism is a rare and potentially fatal paralytic disease caused by botulinum neurotoxin (

257 falciparum manifests in many organ-specific fatal pathologies, including cerebral malaria (CM), driv

258 In fatal pediatric disease, our results corroborate an incr

259 ICANCE STATEMENT Aralar deficiency induces a fatal phenotype in humans and mice and is associated wit

260 pression of LAP is directly linked with some fatal physiological and pathological disorders.

261 Silicosis is an ancient and potentially fatal pneumoconiosis caused by exposure to respirable cr

262 Pulse oximetry identified fatal pneumonia episodes at HCs in Malawi that would oth

263 of our current understanding of hCoV-induced fatal pneumonia in the elderly.

264 unistic pathogen that causes the potentially fatal pneumonia Legionnaires' Disease.

265 One patient had fatal pneumonia that was assessed by the investigator to

266 Chronic wasting disease (CWD) is a fatal, progressive disease that affects cervid species,

267 m (RR 2.22, 95% CrI 1.78-2.89, p<0.0001) and fatal pulmonary embolism (1.58, 1.14-2.19, p=0.01), but

268 a primary endpoint, and pulmonary embolism, fatal pulmonary embolism, and major bleeding as secondar

269 ded similar results for all endpoints except fatal pulmonary embolism, where evidence of an effect wa

270 likewise augment the risk of severe or even fatal reactions.

271 ant to conventional treatments, resulting in fatal relapse of the disease.

272 The latter can lead to potentially fatal renal failure and is caused by the release of Shig

273 Here, we report a case of fatal respiratory diphtheria caused by toxigenic C. diph

274 Diphtheria is a potentially fatal respiratory disease caused by toxigenic Corynebact

275 mans, causing outbreaks of severe, and often fatal, respiratory illness.

276 isrupting the Gorab gene in mice resulted in fatal saccular maturation defects characterized by a thi

277 We find that local exposure to fatal school shootings increases youth antidepressant us

278 id CSCC progression; another resulted from a fatal second aggressive head and neck squamous cell carc

279 ge 8 weeks and a higher proportion developed fatal sepsis during the neonatal period.

280 eatment, this infection can result in highly fatal septicemia.

281 Severe and fatal SFTS presents as a hemorrhagic fever characterized

282 Fatal sting reactions are exceedingly rare, but certain

283 All incidences of fatal and non-fatal stroke during the study period were recorded by ty

284 fined as a composite of all-cause death, non-fatal stroke, or non-fatal myocardial infarction) in pat

285 impaired NK cell maturation in a child with fatal susceptibility to CMV.

286 infection (CDI) causes serious and sometimes fatal symptoms like diarrhea and pseudomembranous coliti

287 Anaphylaxis is a severe, potentially fatal, systemic allergic reaction.

288 Fatal tachyarrhythmias invariably occurred in the presen

289 also be important, particularly for rapidly fatal tumors, with associations differing by structural

290 to the brain; those widely disseminated are fatal typically in 3-4 months, even with the best availa

291 a cardiac action potential that can trigger fatal ventricular arrhythmias.

292 cholerae, the bacterium responsible for the fatal water-borne cholera disease, uses the T6SS to evad

293 is a bacterial plant pathogen that causes a fatal wilt infection in some cucurbit crop plants.

294 This disease is uniformly fatal, with intratumor heterogeneity the major reason fo

295 h usually involves the liver, and is usually fatal within 1 year.

296 apidly progressive dementia which is usually fatal within six months.

297 It can be fatal without proper treatment.

298 is a vector-borne disease that is typically fatal without treatment.

299 Duchenne muscular dystrophy (DMD) is a fatal X-linked disorder caused by nonsense or frameshift

300 Pelizaeus-Merzbacher disease is a fatal X-linked leukodystrophy caused by mutations in the