ライフサイエンスコーパス: fatty alcohol

1 no effect is observed with the corresponding fatty alcohol.

2 tritional significance of dietary long chain fatty alcohols.

3 ctions between such inorganic structures and fatty alcohols.

4 acyl-CoAs enabled the efficient synthesis of fatty alcohols.

5 ta consistent with cationic trimethylarsenio fatty alcohols.

6 of fatty acid derivatives, including primary fatty alcohols.

7 l-acyl carrier protein substrates to primary fatty alcohols.

8 ing strategy to enable sustainable supply of fatty alcohols.

9 ly affected by the number of carbon chain of fatty alcohols.

10 encoded isozymes that reduced fatty acids to fatty alcohols.

11 ose cells and results in the accumulation of fatty alcohols.

12 are key enzymes for microbial production of fatty alcohols.

13 Here, we report a set of avocado fatty alcohols/acetates (AFAs) that exhibit nematocidal

14 il bodies) were enzymatically converted into fatty alcohols across a broad chain-length range (C(8)-C

15 os have an endogenous fatty acyl-coenzyme A: fatty alcohol acyl-transferase activity that could accou

16 x synthase (WS, fatty acyl-coenzyme A [coA]: fatty alcohol acyltransferase) catalyzes the final step

17 ncrease the production of fatty-acid-derived fatty alcohols, alkanes and olefins up to 700%.

18 ated fatty acid (alpha-ClFA) and chlorinated fatty alcohol (alpha-ClFOH).

19 Nevertheless, the 75% reduction in total fatty alcohol and diol loads in the seed coat resulted i

20 FADH proteins are active on very-long-chain fatty alcohol and fatty aldehyde substrates, respectivel

21 saturated, unsaturated, and polyunsaturated fatty alcohols and acids.

22 3) strains that were capable of synthesizing fatty alcohols and alkanes.

23 hyl-delta(22)-coprostenol, several secondary fatty alcohols and dicarboxylic acids were identified fo

24 These results suggest that fatty alcohols and diols play an important role in deter

25 ers are synthesized by the esterification of fatty alcohols and fatty acids.

26 Such fatty alcohols and hydroxycinnamic acids are also presen

27 observations suggest that the interaction of fatty alcohols and inorganic mineral structures could ha

28 Aliphatic hydrocarbons such as fatty alcohols and petroleum-derived alkanes have numero

29 t level during seed desiccation, whereas the fatty alcohols and saturated omega-hydroxy fatty acids c

30 ingle-chain amphiphiles such as fatty acids, fatty alcohols, and fatty-acid glycerol esters are extre

31 over 1 g/L of medium-chain free fatty acids, fatty alcohols, and methyl ketones.

32 ar species including fatty acids, n-alkanes, fatty alcohols, and sterols.

33 ucturally tailored fatty esters (biodiesel), fatty alcohols, and waxes directly from simple sugars.

34 Fatty alcohols are value-added chemicals and important c

35 erent metabolically engineered cell systems (fatty alcohol biosynthesis, bioluminescence light genera

36 refore, our results indicate that esterified fatty alcohols, both soluble and polymerized forms, repr

37 , the catalytic conversion of fatty acids to fatty alcohols (C(8)-C(16)) or fatty alkanes (C(7)-C(15)

38 y and convert them to versatile medium chain fatty alcohols (C10 &C12).

39 maceuticals and cosmetics while medium chain fatty alcohols (C6-C12) could be used as diesel-like bio

40 in root waxes of NaCl-treated wild-type and fatty alcohol:caffeoyl-CoA caffeoyl transferase plants.

41 ate, thus we have named this acyltransferase FATTY ALCOHOL:CAFFEOYL-CoA CAFFEOYL TRANSFERASE.

42 Fatty alcohols can be considered plausible prebiotic amp

43 hain length and specific for fatty acids and fatty alcohols containing very long saturated acyl chain

44 he reductase activity of FAR1, given that no fatty alcohols could be detected.

45 eport, for the first time, that medium chain fatty alcohols could be produced in yeast via targeted e

46 The integration of a medium-chain fatty alcohol, decanol, within these inorganic minerals,

47 l-coenzyme A to omega-hydroxyfatty acids and fatty alcohols, demonstrating that the gene encodes a fe

48 raction has led to the isolation of five new fatty alcohol derivatives, avocadenols A-D (1-4) and avo

49 t altered, indicating that reduced levels of fatty alcohols did not influence the suberin polymerizat

50 for 9d, suggesting that the straight-chained fatty alcohol esters were more therapeutically selective

51 By contrast, plants deficient in fatty alcohols exhibited elevated drought tolerance, whi

52 Fatty alcohols (FAlc) and aldehydes (FAld) are essential

53 carbons - HCs, free fatty acids - FFAs, free fatty alcohols - FALs and wax esters - WEs) of natural w

54 FAR1 reduces fatty acids to their respective fatty alcohols for the plasmalogen-biosynthesis pathway.

55 specific focus is placed on fatty acids and fatty alcohols for their natural availability, low toxic

56 R4, and FAR5, which collectively produce the fatty alcohols found in suberin, reduced their levels by

57 The fatty alcohol fractions from the genetically modified pl

58 gineering strategies utilize FARs to produce fatty alcohols from intracellular acyl-CoA and acyl-ACP

59 Microbial production of fatty alcohols from renewable feedstock stands as a prom

60 Long chain fatty alcohols (>C12) are mainly used in surfactants, lu

61 The mammalian enzymes that synthesize fatty alcohols have not been identified.

62 cient in the incorporation of the long chain fatty alcohol, hexadecanol, into complex lipids.

63 named this enzyme P. trichocarpa hydroxyacid/fatty alcohol hydroxycinnamoyltransferase 1 (PtFHT1).

64 d esters between selected phenolic acids and fatty alcohols in a binary solvent system, composed of h

65 is of the distribution of the C18:0 to C22:0 fatty alcohols in Arabidopsis (Arabidopsis thaliana) roo

66 The conversion of fatty acids to fatty alcohols is required for the synthesis of wax mono

67 To convert acids to oleochemicals (e.g., fatty alcohols, ketones), the narrowed fatty acid pool n

68 ine, CHO-K1, that is deficient in long-chain fatty alcohol:NAD+ oxidoreductase (FAO; EC 1.1.1.192).

69 ass spectrometry techniques that most of the fatty alcohols not covalently linked to the suberin poly

70 ulsion systems, caffeic acid esterified with fatty alcohols of different chain lengths (C1-C20) were

71 ratio (R) between long chain fatty acids and fatty alcohols on the oil foam.

72 examine the effect of carbon chain length of fatty alcohols on the reaction rate, the esterifications

73 K1B, were deficient in long-chain-fatty alcohol oxidase (FAO) activity.

74 to fatty acids by the sequential action of a fatty alcohol oxidase (FAO) and a fatty aldehyde dehydro

75 on analyses suggested that the deficiency in fatty alcohol oxidation in the FAA.K1A cells and the SLS

76 in Arabidopsis enhanced the in vivo rate of fatty alcohol oxidation more than 4-fold.

77 FAO and FADH constitute the very-long-chain fatty alcohol oxidation pathway that is likely to be nec

78 eate, arachidonate, and docosahexanoate), or fatty alcohols (palmityl, petrosenlinyl, and ricinolenyl

79 Avocado-derived polyhydroxylated fatty alcohols (PFAs), such as avocadene and avocadyne,

80 , only the LPA(2) receptor-selective agonist fatty alcohol phosphate-12 mimics the IL-4-dependent eff

81 esis and pharmacological characterization of fatty alcohol phosphates (FAP) containing saturated hydr

82 We previously reported that fatty alcohol phosphates (FAP) represent a minimal pharm

83 We synthesized fatty alcohol phosphates and thiophosphates and found th

84 Fatty alcohols play a variety of biological roles in all

85 ehydrogenase) could also be used to increase fatty alcohol production but resulted in less yield enha

86 and acetyl-CoA carboxylase further improved fatty alcohol production by 1.4-fold.

87 OAHFA, and diacylated alpha,omega-dihydroxy fatty alcohols remained invariable in both races, barrin

88 Although fatty alcohols represent only minor components of the su

89 sis root waxes and that FAR1/4/5 provide the fatty alcohols required for alkyl hydroxycinnamate synth

90 eductase 1 (Far1) is essential for supplying fatty alcohols required for ether bond formation in ethe

91 n ether phospholipids are characterized by a fatty alcohol residue at the sn-1 position of their glyc

92 data showed esterified and free fatty acids, fatty alcohol, sterols, alkanes and aromatic acid deriva

93 The data suggest that fatty alcohol synthesis in mammals is accomplished by tw

94 ineer enzymes that produce over twofold more fatty alcohols than the starting natural sequences.

95 y for the production of alcohols, especially fatty alcohols that find broad applications in consumer

96 A fatty alcohol titer exceeding 350 mg.L(-1) was obtained

97 of arsenolipids as cationic trimethylarsenio fatty alcohols (TMAsFOH).

98 the reduction of fatty acid methyl esters to fatty alcohols to facilitate high-quality chromatographi

99 compound belonging to tocopherol long-chain fatty alcohols, to promote oligodendrocyte regeneration

100 hanol including fatty esters into respective fatty alcohols was shown.

101 squalene, sterols, triterpene acids/esters, fatty alcohols, wax esters and phenols (lignans, tyrosol

102 ion using glucose as the sole carbon source, fatty alcohols were produced at 1.3 g/L, including 6.9%

103 FAR-like domain produced both 16:0 and 18:0 fatty alcohols, whereas the C-terminal acyltransferase-l

104 alyzed reduction of fatty acyl-coenzyme A to fatty alcohols, which are possible precursors of platele

105 lipids and wax esters requires as precursors fatty alcohols, which are synthesized by fatty acyl redu

106 tion, WE hydrolysis releases very-long-chain fatty alcohols, which must be oxidized to fatty acids by

107 the esterifications of C4-C18 straight-chain fatty alcohol with dihydrocaffeic acid (DHCA), as a mode

108 desired specificities for the production of fatty alcohols with industrial value.