ライフサイエンスコーパス: feedforward

1 s: 88% and brain datasets: 66%) using LAmbDA Feedforward 1 Layer Neural Network with bagging.

2 This feedforward ACh-NGF axis activates the gastric cancer ni

3 Thus, a feedforward ACK1/pY88-H4/WDR5/MLL2/AR epigenetic circuit

4 ls have similarities, such as including both feedforward and feedback connections, allowing informati

5 oring deep-layer firing rates and modulating feedforward and feedback connectivity.

6 s is based on the laminar patterns of direct feedforward and feedback cortico-cortical projections.

7 network and suggest that the integration of feedforward and feedback information is implemented by c

8 ronal dynamics supporting integration of the feedforward and feedback information.

9 ressing (PV+) GABAergic interneurons mediate feedforward and feedback inhibition and have a key role

10 after, fast auditory fiber activity promotes feedforward and feedback inhibition mediated by PV(+) in

11 promised in early postnatal days as was both feedforward and feedback inhibition onto pyramidal neuro

12 the input stage of the cerebellum, providing feedforward and feedback inhibition through mossy fiber

13 dams exhibited compromised CCK-INT-mediated feedforward and feedback inhibition.

14 Both feedforward and feedback inhibitory input onto pyramidal

15 nsistent with an extensive interplay between feedforward and feedback inputs to the bulb.

16 al sensory networks in immune cells, such as feedforward and feedback loops or ligand antagonism, som

17 itory interneurons, organized into canonical feedforward and feedback motifs, play a key role in cont

18 rcuit level that loss of EphA4 disrupts both feedforward and feedback motor pathways, resulting in de

19 loss of EphA4 disrupts the function of both feedforward and feedback motor pathways, resulting in de

20 cal layers of a V1 column, and reflects both feedforward and feedback processing.

21 areas are interconnected via layer-specific feedforward and feedback projections.

22 Finally, feedforward and feedback pulvino-cortical pathways parti

23 , the Flash-Grab Effect, to disassociate the feedforward and feedback representation of an adaptor.

24 ve contributions to cortical adaptation from feedforward and feedback signals, taking advantage of a

25 present a supervised learning scheme for the feedforward and recurrent connections in a network of he

26 We introduce feedforward and recurrent networks and explain the expre

27 ctures inside these normal subgroups forming feedforward and recurrent networks made of blocks of imp

28 It is unclear to what extent feedforward and recurrent processes contribute in object

29 halography to localize, track and decode the feedforward and recurrent processes of reading, as elici

30 ption depends on a complex interplay between feedforward and recurrent processing.

31 motor system and based on the integration of feedforward and sensory feedback signals.SIGNIFICANCE ST

32 aptation paradigm to investigate if feedback/feedforward and unilateral/bilateral contributions to lo

33 from area V1 illustrate the strength of the feedforward approach.

34 ls of sensory processing in the brain have a feedforward architecture in which each stage comprises s

35 e in temperature is well predicted through a feedforward Artificial Neural Network.

36 ve feedback, mutual repression, and coherent feedforward, as well as signaling interaction circuitry.

37 (or one-shot) production is responsible for feedforward audience design effects, or effects based on

38 Furthermore, IL-1beta signals via a feedforward autocrine loop to promote invasion through a

39 ory cortex activity as well as modulation of feedforward, but not feedback, coupling within a temporo

40 (dlPFC) express the molecular machinery for feedforward, cAMP-PKA-calcium signaling.

41 leads to a mature adaptive response whereby feedforward changes in motor output mirror both the ampl

42 e, a process that prevents initiation of the feedforward chemoattractant signaling cascade that resul

43 ting of both the A(2B)-mediated ADO-CAF-CD73 feedforward circuit and A(2A)-mediated immune suppressio

44 These data reveal a feedforward circuit in which post-transcriptional oligoa

45 This feedforward circuit is essential for intestinal remodeli

46 enhanced via an ADO-A(2B) receptor-mediated feedforward circuit triggered by tumor cell death, which

47 Therefore, these data describe a feedforward circuit whereby HAT1 captures acetyl groups

48 d tissue-specific gene expression requires a feedforward circuit whereby Ikaros down-regulates the ex

49 the dynamics of eS6-P can be explained by a feedforward circuit with inputs from both circadian and

50 iscerosensory signals, placing them within a feedforward circuit within the NTS.

51 ferents, indicating that they form part of a feedforward circuit.

52 However, afferent connections often bypass feedforward circuitry, suggesting that a different GABAe

53 lly segregated and topographically organized feedforward circuits are thought to modulate multiple be

54 It remains elusive how FSI-based feedforward circuits regulate the output of NAc MSNs.

55 eats relies on a combination of feedback and feedforward circuits.

56 he E/I balance occurred in feedback, but not feedforward, circuits.

57 Furthermore, the feedforward combination of strong soma-to-axon coupling

58 hold) and then outperforms parameter-matched feedforward comparison models.

59 rocessing is described as a cascade of local feedforward computations.

60 etail the functional benefit of the strongly feedforward configuration that has been observed in phys

61 tabolic and neural processes was specific to feedforward connections linking the visual and dorsal at

62 ntal and occipital regions, and strengthened feedforward connections within the left hemisphere.

63 l and occipital regions and strengthening of feedforward connections within the left hemisphere.

64 dulatory, in contrast to fast, high-efficacy feedforward connections.

65 n internal models that are delivered via non-feedforward connections.

66 Even though models with random feedforward connectivity are capable of creating computa

67 patients' deviation from predicted "normal" feedforward connectivity based on the support vector reg

68 tional connectivity for adaptation: enhanced feedforward connectivity from V1 to higher visual areas,

69 They examined relationships between feedforward connectivity, and delusional thinking and po

70 chanisms, and what the roles of feedback and feedforward control are in the generation of compensator

71 Experiment 1 tested feedforward control by examining speech adaptation acros

72 he recurrent model emulates the behaviour of feedforward control models in that it achieves the same

73 typically-developing children develop mature feedforward control of ankle muscle activity as they age

74 ry toe walking in adults is characterized by feedforward control of ankle muscles in order to ensure

75 about past network output and contributes to feedforward control of subsequent locomotor bouts.

76 its functional contribution to feedback and feedforward control remains controversial.

77 t the cerebellum forms a crucial part of the feedforward control system for speech but is not essenti

78 The patients were impaired in adapting their feedforward control system relative to controls, exhibit

79 ch are inhibited by glucocorticoids, provide feedforward control to limit expression of the transcrip

80 ystems and develop an endoribonuclease-based feedforward controller that can adapt the expression lev

81 nvolutional neural network models outperform feedforward convolutional models matched in their number

82 Feedforward Convolutional Neural Networks (ffCNNs) have

83 coordination within V4, but not V1, and with feedforward coordination between V1 and V4.

84 T response patterns were poorly predicted by feedforward deep CNN activations.

85 nd size of scatterers are calculated using a feedforward deep neural network (DNN) and convolutional

86 ct space to describe general objects using a feedforward deep neural network trained on object classi

87 each brain area depends on a combination of feedforward drive (bottom-up from the previous processin

88 ying at distinct depths relay the excitatory feedforward drive from photoreceptors to amacrine and ga

89 tially and temporally separated instances of feedforward driven activity.

90 have relatively reduced parietal-prefrontal feedforward effective connectivity during context updati

91 eristics, showing that in the visual system, feedforward excitation and inhibition are driven with eq

92 la mushroom body, where Kenyon cells receive feedforward excitation from olfactory projection neurons

93 direct OSN signals and capable of mediating feedforward excitation of MCs.

94 ed behind neighboring units and imposed weak feedforward excitation within the local column.

95 pled with more modest, variable reduction in feedforward excitation, driving a common increase in E-I

96 ement with the known pathophysiology we find feedforward excitatory drive is reduced in HD compared t

97 Animals must integrate feedforward, feedback and intrinsic mechanical control m

98 Overall, we suggest that feedforward/feedback information loops in hierarchical n

99 We focus on the feedforward flow of information from sensory neurons to

100 le of gamma-band activity (40-100 Hz) in the feedforward flow of sensory information, whereas feedbac

101 The analysis reveals that this feedforward flow traverses a small core ("hourglass wais

102 robust to the methodology that separates the feedforward from the feedback flow of information.

103 aptation, as well as the influence of PVs on feedforward functional connectivity in the circuit.

104 SGCs directly, as well as indirectly through feedforward GABAergic/cholinergic signals mediated by st

105 ys processing-predicted inputs by inhibiting feedforward gamma rhythms and associated spiking.

106 Hence, unlike feedforward glutamatergic transmission, which spills ove

107 ehavioral goals, which contrasts with simple feedforward, hierarchical models of visual processing.

108 esting the importance of class 1 synapses in feedforward, hierarchical processing.

109 , presumably forming a core component of its feedforward hierarchy.

110 experimental evidence, that SM results from feedforward, horizontal, and feedback interactions with

111 asures have transformed our understanding of feedforward information processing in the brain's sensor

112 of delusion formation implicate deficits in feedforward information updating across the posterior to

113 ry interneurons (INs) gate PN plasticity via feedforward inhibition (FFI).

114 These findings elucidate a new mechanism of feedforward inhibition and refine mechanisms by which GA

115 Synaptic recruitment of feedforward inhibition and subsequent GABA release from

116 ng input-specific plasticity, reciprocal and feedforward inhibition are found to be differentially re

117 ssue of Neuron, Pan et al. (2019) identify a feedforward inhibition circuit in the spinal cord dorsal

118 This caused the ratio between excitation and feedforward inhibition elicited by MD input to shift tow

119 ynapses tuned to different orientations, but feedforward inhibition generates a high-pass filter that

120 In addition, we also report an impairment in feedforward inhibition in CA3 pyramidal cells.

121 (2019) find reduced feedforward inhibition in cortical neurons in four genet

122 All autism mutants showed reduced feedforward inhibition in layer 2/3 coupled with more mo

123 ystem and found evidence for a dual role for feedforward inhibition in seizures: while inhibition at

124 evealed tightly clustered boutons that focus feedforward inhibition in the neighborhood of GoC somata

125 ut to the striatum that exclusively recruits feedforward inhibition mechanisms.SIGNIFICANCE STATEMENT

126 to CA3 pyramidal cells combines with robust feedforward inhibition mediated by both GABAA and GABAB

127 and orchestrate their spiking activity using feedforward inhibition mediated by dCA1-connected parval

128 ns the ability of sensory afferents to evoke feedforward inhibition of adult spinal projection neuron

129 esents one mechanism contributing to reduced feedforward inhibition of ascending projection neurons,

130 SI synapses, entailing enhanced FSI-mediated feedforward inhibition of MSNs upon BLA activation.

131 ns directly innervate the brainstem to drive feedforward inhibition of nociceptive neurons.

132 ese augmented synaptic connections mediate a feedforward inhibition of projections from the PFC to th

133 Overall, this resulted in a robust and slow feedforward inhibition of spike transfer at mf-CA3 pyram

134 n to the striatum which selectively recruits feedforward inhibition of spiny neurons without any acco

135 vefront fails, allowing seizure propagation, feedforward inhibition of the surrounding centimeter-sca

136 lude a reduction in primary afferent-evoked, feedforward inhibition onto adult projection neurons.

137 g in the adult CNS, including a reduction in feedforward inhibition onto ascending projection neurons

138 is is predicted to contribute to the loss of feedforward inhibition onto mature projection neurons, a

139 ty of methods in mice of either sex to study feedforward inhibition recruited by identified MFs, focu

140 owerful direct excitatory input and indirect feedforward inhibition to CA3 pyramidal neurons.

141 The dorsal cochlear nucleus also drove feedforward inhibition to VIP neurons, indicating that i

142 xcite nuclear neurons and drive polysynaptic feedforward inhibition via Purkinje neurons, setting up

143 reciprocal inhibition was strengthened while feedforward inhibition was weakened, and the two motifs

144 We conclude that compromised feedforward inhibition within the local circuit generate

145 considered to be critically involved in this feedforward inhibition, but it is not known what role, i

146 , FS neurons track thalamic input, mediating feedforward inhibition.

147 ke timing of striatal projection neurons via feedforward inhibition.

148 ng of the projection neurons in part through feedforward inhibition.

149 activity through its powerful and sustained feedforward inhibition.

150 neurons and inhibit the striatal output via feedforward inhibition.

151 ially involving an increased feedback and/or feedforward inhibition.

152 requency bursts and recruitment of the local feedforward inhibition.

153 gh top-down cortical excitation and thalamic feedforward inhibition.

154 trengthening as well as a transient surge in feedforward inhibition.

155 the density of bouton filopodia that provide feedforward inhibition.

156 ciated neuro-modulatory tone that may reduce feedforward inhibition.

157 expands the range of cortical output through feedforward inhibition.SIGNIFICANCE STATEMENT The primar

158 ss of spike train influence, reciprocal- and feedforward-inhibition motifs were quantified.

159 nd on the GABAergic synaptic input through a feedforward inhibitory circuit also involving the hyperp

160 istributed throughout the NAc, forming local feedforward inhibitory circuits.

161 ptic transmission and the function of the TC feedforward inhibitory microcircuit in a mouse model of

162 re, we investigated the thalamocortical (TC) feedforward inhibitory microcircuit in FHM1 mice of both

163 or the integration time window set by the TC feedforward inhibitory microcircuit was altered in FHM1

164 excitatory-inhibitory balance set by the TC feedforward inhibitory microcircuit, whereby the balance

165 s to the NAc direct MSN output by recruiting feedforward inhibitory microcircuits comprised of parval

166 n reward circuitry, elucidate a novel arm to feedforward inhibitory networks, and inform the growing

167 erneurons inhibiting other interneurons) and feedforward (inhibitory interneurons inhibiting principa

168 ucleus neurons to disentangle reciprocal and feedforward-inhibitory motifs.

169 vide a direct, quantifiable demonstration of feedforward input convergence in vivo.

170 ms in V4 that became apparent when the major feedforward input to V4 was removed by lesioning V1: alt

171 real neurons, and while the ability to relay feedforward inputs remained intact, reduced models showe

172 terestingly, feedback inputs often outnumber feedforward inputs.

173 the visual system are inherited mainly from feedforward inputs.

174 ated by a model wherein cells receive random feedforward inputs.

175 Here, we show that an feedforward insulin-Myc loop promotes mitochondrial resp

176 mplex cell lineages that include feedback or feedforward interactions.

177 cal (interneurons inhibiting each other) and feedforward (interneuron inhibiting the principal neuron

178 y in cortical networks, arising from a rapid feedforward interneuronal response to focal activity.

179 omboid production in enterocytes, catalyzing feedforward ISC hyperplasia.

180 e additional recurrent processing beyond the feedforward IT response.

181 Molecular Cell, Roake et al. (2019) define a feedforward kinetic pathway consisting of a cycle of oli

182 ion efficacy than postsynaptic activity, and feedforward local circuits often displayed the largest f

183 diverse chromatin states of coherent type-1 feedforward loop (C1-FFL) and incoherent type-1 feedforw

184 ts target genes opa and D form an incoherent feedforward loop (FFL) and a new mechanism allowing the

185 natural and synthetic miRNA-based incoherent feedforward loop (iFFL) circuits that mitigate gene expr

186 genes, establishing an miR-30e-3p/TP53/MDM2 feedforward loop and accounting for miR-30e-3p dual role

187 The incoherent feedforward loop and the essential role of p53 activatio

188 This TIC-driven, IL-33-TGF-beta feedforward loop could potentially be exploited for canc

189 We conclude that RASSF1A-HIF-1alpha forms a feedforward loop driving hypoxia signaling in PH and can

190 uppel-like factor 9 knockdown, we revealed a feedforward loop in glucocorticoid receptor signaling, p

191 t that MTHFD2 and HIF-2alpha form a positive feedforward loop in RCC, promoting metabolic reprogramin

192 ing negative auto-regulation and/or coherent feedforward loop motifs to the basic signal integration

193 airway macrophages, which is suggestive of a feedforward loop of T(H)1 cell recruitment.

194 A model based on a putative feedforward loop orchestrated by Akt consistently predic

195 l cytoskeleton dynamics and thus establish a feedforward loop that ensures a proper angiogenic respon

196 EN-PI3K-FOXO-USP11 constitute the regulatory feedforward loop that improves the stability and tumor s

197 to induce cytochrome c release, generating a feedforward loop that leads to hepatocyte death.

198 S-dependent NO production was required for a feedforward loop that maintains CYGB expression.

199 AURKB transcription, constituting a positive feedforward loop that reinforces MYC-regulated oncogenic

200 IP to temper synaptic potentials (incoherent feedforward loop) and miR-1010 to reduce nAcRbeta2 mRNA

201 lpha nuclease interrupts the five components feedforward loop, E1A, E3-19K, IRE1alpha, XBP1s, E1A enh

202 break in the glucocorticoid-induced positive feedforward loop.

203 dforward loop (C1-FFL) and incoherent type-1 feedforward loops (I1-FFL) contributed to the dynamic ex

204 lower sucrose in the roots, indicating that feedforward loops enhanced sink capacity in the high lig

205 w Six1 cooperates with distinct cofactors in feedforward loops to control lineage-specific gene expre

206 Conclusively, our results support a feedforward mechanism between STAT3 and PRL-3 that prolo

207 tyrosine kinase-MAPK signalling as part of a feedforward mechanism involving mammalian target of rapa

208 I3K/FOXO pathway, and further show that this feedforward mechanism is implicated in its tumor-suppres

209 e in their firing rate in vivo, suggesting a feedforward mechanism mediating the inhibition of spiny

210 at the level of RIAM through a FAK-mediated feedforward mechanism that involves reversal of autoinhi

211 increase extracellular D-serine, providing a feedforward mechanism to increase synaptic NMDAR activat

212 Such a feedforward mechanism would ensure adequate provision of

213 se limits on the proposed role of gamma as a feedforward mechanism.

214 We infer that TLAs convey feedforward mechanosensory stimuli to transiently activa

215 CNet builds on a generalized sequential feedforward method, augmented by a down-sampling bootstr

216 t parvalbumin-expressing interneurons within feedforward microcircuits heterosynaptically target GABA

217 e results support the rapid integration of a feedforward model during perception and provide a neurop

218 models clearly outperform parameter-matched feedforward models in terms of their ability to capture

219 veral parameter-matched and state-of-the-art feedforward models.

220 est that the postural controller possesses a feedforward module that uses move commands to calculate

221 Skilled forelimb movements are initiated by feedforward motor commands conveyed by supraspinal motor

222 measure the temporal characteristics of the feedforward motor output during the decay of learning.

223 ory signalling necessary for optimization of feedforward motor programs.

224 Emerging feedforward network (FN) models can provide high predict

225 dge, we propose a forest graph-embedded deep feedforward network (forgeNet) model, to integrate the G

226 gical units, such as the graph-embedded deep feedforward network (GEDFN) model, has been a solution t

227 rate-a relationship previously explained in feedforward networks driven by correlated input-emerges

228 Analyses of idealized feedforward networks suggest that several conditions hav

229 is comparable to the performance of standard feedforward networks trained end-to-end with a backpropa

230 reliably through 4 layers, unlike idealized feedforward networks, which tended strongly towards sync

231 nput gating and subthreshold gain control in feedforward networks.

232 Deep feedforward neural network models of vision dominate in

233 Here, we developed a deep learning feedforward neural network trained on fractional Brownia

234 A two-layer feedforward neural network using the same features is ab

235 gue of classical neurons, which form quantum feedforward neural networks capable of universal quantum

236 computational models based on the canonical feedforward neuronal circuit and included electrical syn

237 s is blocked, suggesting that it arises from feedforward, not feedback, computations.

238 is behavior, then primates should outperform feedforward-only deep CNNs for images that require addit

239 havior to become more like those produced by feedforward-only ventral stream models.

240 ot due to LC modulation of trigeminothalamic feedforward or corticothalamic feedback inputs.

241 connection patterns between areas as either feedforward or feedback, and generated testable predicti

242 Within this framework, feedforward (or one-shot) production is responsible for

243 unctionality of single cells: a hierarchical feedforward organization of large laminar neuronal strat

244 the ferret, a visual carnivore with distinct feedforward parallel processing streams, and compared th

245 ally derived observations support a role for feedforward parietal-prefrontal information processing d

246 models to address individual variability in feedforward parietal-prefrontal information updating in

247 the auditory cortex in conjunction with the feedforward pathway from the auditory cortex to the amyg

248 ing more broadly distributed-consistent with feedforward pathway mediation.

249 FICANCE STATEMENT During sensory processing, feedforward pathways carry information such as receptive

250 In the visual system, these feedforward pathways define the classical feedforward re

251 Although much is known about how feedforward pathways shape receptive field properties of

252 piking of NPY+ cells, suppresses both of the feedforward pathways to CA1.

253 electrical channel combining the ON and OFF feedforward pathways within the output layer of the reti

254 zed by the combination of a slow-progressive feedforward process and a fast-reactive feedback-driven

255 ocessing is commonly viewed and studied as a feedforward process.

256 perception can be best explained as a purely feedforward process.

257 ir appearance, is largely solved through the feedforward processing of visual information.

258 t that theta is more tightly associated with feedforward processing than gamma and pose limits on the

259 As expected, class 1 synapses subserve the feedforward projection from primary to secondary sensory

260 Further, learning increases feedforward rather than feedback layer-to-layer connecti

261 This phenomenon has often been attributed to feedforward readout of the neural activity by the downst

262 se feedforward pathways define the classical feedforward receptive field (ffRF), the area in space in

263 ack enables gradient detection, and coherent feedforward regulation underlies cellular memory.

264 As a consequence of this incoherent feedforward regulation, PP2A-B55 activity rises concurre

265 Thus, CDK1, YTHDF2, and WEE1 form a feedforward regulatory loop to promote mitotic entry.

266 thetic axis; these neurons engage incoherent feedforward regulatory loops via activation of distinct

267 We first confirm that a feedforward response propagates through the ventral and

268 formation-processing hierarchies beyond pure feedforward schemes.

269 ed visual processing-despite showing minimal feedforward selectivity for visual features [19, 20]-und

270 ual action by beta-catenin as a signal and a feedforward sensor.

271 Despite our extensive knowledge of the feedforward sensory features that drive cortical neurons

272 his misaligned choice information allows the feedforward sensory information to coexist with the deci

273 gal cholinergic input with highly convergent feedforward sensory input.

274 n fluctuating environments, and represents a feedforward sensory mechanism with implications for othe

275 ma and theta oscillations might both reflect feedforward sensory processing from V1 to V4.(6-10) Here

276 f Cancer Cell, Hayakawa et al. demonstrate a feedforward signaling loop in which tumor-derived nerve

277 (2020) identify a feedforward signaling mechanism that couples neuronal ac

278 on zone (LPZ),(6) despite the absence of the feedforward signals from the degenerated retina.

279 Although the LGN's role in relaying feedforward signals from the retina to the cortex is wel

280 xperimental approaches based on knowledge of feedforward signals have promoted greater understanding

281 stimulus, which tends to be more linked with feedforward signals.

282 nals can be partially suppressed by residual feedforward signals.

283 Despite this, feedforward spiking, synaptic depolarization, and sponta

284 may not reflect a modulation of the initial feedforward sweep, it does reveal a modulation of early

285 of abstraction than what is afforded by the feedforward sweep.

286 Inflammatory signals induce feedback and feedforward systems that provide temporal control.

287 ew role for mEC LV as a bifurcation gate for feedforward (telencephalic) and feedback (entorhinal-hip

288 L4 neurons receive both feedforward thalamocortical and recurrent intracortical

289 balance of primate visual cortex, enhancing feedforward thalamocortical gain while suppressing corti

290 dynamically rebalance inhibitory feedback or feedforward to other neurons types in the OB in response

291 r-order thalamic nuclei, creating a parallel feedforward trans-thalamic pathway.

292 In addition, there is feedforward transcriptional control of G-protein signali

293 transcriptional modules that converge with a feedforward transcriptional logic.

294 ier steady-state activation, consistent with feedforward tuning of activation phase to compensate for

295 Feedforward V1-to-V4 connectivity, mediated by gamma osc

296 ng rates, and the functional consequences of feedforward versus recurrent dynamics, ideas that may sh

297 ted feedback signals rather than reorganized feedforward visual inputs.

298 a variety of highly visual mammals in which feedforward visual pathways are organized into parallel

299 lay neurons obey or ignore the separation of feedforward visual signals into parallel processing stre

300 eting hypotheses about the brain mechanisms (feedforward vs. feedback) that mediate adaptive processi