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1 port, neutralizing the natriuretic effect of fenoldopam.
3 ured during three fixed, escalating doses of fenoldopam (0.03, 0.1, and 0.3 Lg/kg/min) on both a high
4 drated and randomized to receive intravenous fenoldopam (0.05 microg/kg/min titrated to 0.10 microg/k
6 ably transfected with rat D1A receptor cDNA, fenoldopam, a D1 agonist, increased phosphatidylinositol
7 in cAMP production in human RPTCs caused by fenoldopam, a D1-like receptor agonist, was attenuated b
8 fore, during, and after a 3-hour infusion of fenoldopam, a D1-like receptor agonist, with and without
12 enoldopam restored the natriuretic effect of fenoldopam and its inhibitory effect on proximal tubule
15 inhibitors, including the FDA-approved drugs Fenoldopam and Olanzapine and their analogs, which act t
16 e, quinidine, xylometazoline, oxymetazoline, fenoldopam, and ropinirole) are approved medications.
17 1 microM DA or a dopaminergic D(1) agonist, fenoldopam, but not with the dopaminergic D(2) agonist q
21 -nine of 338 patients (20%) allocated to the fenoldopam group and 60 of 329 patients (18%) allocated
22 tality at 30 days was 78 of 338 (23%) in the fenoldopam group and 74 of 329 (22%) in the placebo grou
23 tension occurred in 85 (26%) patients in the fenoldopam group and in 49 (15%) patients in the placebo
24 lic blood pressure was slightly lower in the fenoldopam group than in the placebo group: 62.5 + 6.4 v
25 signing future studies exploring the role of fenoldopam in preventing or treating renal failure in pa
26 arly, the specific dopaminergic D(1) agonist fenoldopam increased lung edema clearance, but quinpirol
31 kinase C (PKC) was also involved, since the fenoldopam-induced increase in PLC-gamma protein was blo
33 h acute kidney injury after cardiac surgery, fenoldopam infusion, compared with placebo, did not redu
41 Experiments with the selective D1 agonist fenoldopam or D2 agonist quinpirole and experiments with
43 dopamine (DA) D1 receptor agonist SKF 82526 (fenoldopam) or the D2 receptor agonist quinpirole were d
48 red in 33.6% of patients assigned to receive fenoldopam vs 30.1% assigned to receive placebo (relativ
49 ehospitalization (17.6% vs 19.9%, P =.66) in fenoldopam vs placebo randomized patients, respectively.