ライフサイエンスコーパス: fibroblast

1 hibitor increased TGFbeta1 expression in the fibroblast.

2 t are comparable to titers in chicken embryo fibroblasts.

3 h retardation, and cellular senescence of DC fibroblasts.

4 ng data point to functional heterogeneity of fibroblasts.

5 creased caveolar mobility in mouse embryonic fibroblasts.

6 from vascular endothelial cells outwards-in fibroblasts.

7 t maximally increased enzyme activity in all fibroblasts.

8 co-culture with corresponding adult cardiac fibroblasts.

9 pread decidualization feature in the stromal fibroblasts.

10 s controls profibrotic signaling in SSc lung fibroblasts.

11 icentric heterochromatin compaction in mouse fibroblasts.

12 uding a subset of immune regulatory ICAM1(+) fibroblasts.

13 HPgammaCD treatment in NPC1 patient-derived fibroblasts.

14 he effects of genetic deletion of Il11ra1 in fibroblasts.

15 f transcriptional control of Ralpha2 in lung fibroblasts.

16 potential of Tet2-deficient mouse embryonic fibroblasts.

17 imity-dependent adhesome in mouse pancreatic fibroblasts.

18 ing with and stabilization of TGFBR1 in lung fibroblasts.

19 as conferred by mouse tail tip or human skin fibroblasts.

20 sulted in reduced activation of PDGFRbeta in fibroblasts.

21 vascular smooth muscle cells, pericytes, and fibroblasts.

22 ins between CADASIL and CAA are expressed by fibroblasts.

23 ization and altering the paracrine effect of fibroblasts.

24 inflammatory polarization of macrophages and fibroblasts.

25 ron genes (STING) pathway in patient-derived fibroblasts.

26 s, as well as monocytes, B cells and stromal fibroblasts.

27 ured human cell lines and in mouse embryonic fibroblasts.

28 in live human platelets and mouse embryonic fibroblasts.

29 her transcription factor expression in mouse fibroblasts.

30 e de novo DNA methylation in mouse embryonic fibroblasts (2i-MEFs) derived from DNA-hypomethylated 2i

31 /Frt system) expressing bioactive TGFbeta in fibroblasts, a cell population present in the microenvir

32 In progeria-patient fibroblasts, a subset of pS22-Lamin A/C-binding sites we

33 lanocortin type 1 receptor (MC(1)), synovial fibroblasts acquire a senescence phenotype characterized

34 amma was found to suppress genes involved in fibroblast activation in hearts of pn-csERRalpha/gamma k

35 Expression of the fibroblast activation protein (FAP) and accumulation of

36 g cancer-associated fibroblasts that express fibroblast activation protein (FAP).

37 , and Gfi1) that can convert mouse embryonic fibroblasts, adult tail-tip fibroblasts and postnatal su

38 Eosinophils tethered to esophageal fibroblasts after LIGHT stimulation via intercellular ad

39 ificantly downregulated TGFbeta signaling on fibroblasts, an effect regulated by A(2A) and A(2B) aden

40 19-81 years) and primary cultures of dermal fibroblast and dermal sheath cells.

41 le involved in human TB, and overlap between fibroblast and myeloid cell markers in tissues.

42 position and tissue stiffening contribute to fibroblast and myofibroblast differentiation and activat

43 as analyzed with three cell lines, mammalian fibroblast and pancreatic and lung cancer cells.

44 Using genetic deletion in mouse embryo fibroblasts and a combination of CRISPR-mediated gene ed

45 We then cultured WI-38 fibroblasts and A549 epithelial cells to probe their mot

46 ion alleles, we show using patients' primary fibroblasts and biochemical assays, that these mutations

47 highlight different networks of macrophages, fibroblasts and cardiomyocytes between atria and ventric

48 ha inhibited myofibroblast activation in IPF fibroblasts and collagen secretion in organotypic cultur

49 leted ELMOD2 in immortalized mouse embryonic fibroblasts and discovered a number of cellular defects,

50 t infection of various cell types, including fibroblasts and epithelial cells resulted in the formati

51 ization of Rb1 (-/-) primary mouse embryonic fibroblasts and in aggressive tumor growth in severe com

52 tabolism." In human Fragile X syndrome (FXS) fibroblasts and in Fmr1(-/y) mouse neurons, closure of t

53 ibition of key transcription factors HES1 in fibroblasts and KLF6 in keratinocytes not only compromis

54 irradiation is not observed in ATM deficient fibroblasts and may indicate the presence of a mechanism

55 stern blot were performed in patient-derived fibroblasts and muscles and in Trip4 knocked-down C2C12

56 -1 depletion in C2C12 and in patient-derived fibroblasts and muscles caused accelerated proliferation

57 In fibroblasts and myofibroblasts, HYAL2 interacts with the

58 n sites on 366 proteins from patient-derived fibroblasts and myotubes.

59 mouse embryonic fibroblasts, adult tail-tip fibroblasts and postnatal supporting cells into induced

60 showed negligible cytotoxicity toward murine fibroblasts and prevented activation of primary bone mar

61 IL-1alpha is sufficient to activate cultured fibroblasts and primary hepatic stellate cells (myofibro

62 ls converge on target tissues, interact with fibroblasts and promote tissue remodelling are beginning

63 he expression of 285 lncRNAs in human dermal fibroblasts and quantified cellular growth, morphologica

64 (TFs) define identities of both the starting fibroblasts and the end product, iPSCs, and are also of

65 nes encoding STING or cGAS in NIH/3T3 murine fibroblasts and the infection of HEK293 and HEK293 T hum

66 ssays for validation in human HD and control fibroblasts and use to elucidate the CSF/brain and perip

67 pare single-cell transcriptional profiles of fibroblasts and vascular mural cells across four murine

68 S was generated from human keratinocytes and fibroblasts and was initially devoid of skin-resident im

69 hole-genome Hi-C data from IMR90 (human lung fibroblast), and (iii) budding yeast whole-genome Hi-C d

70 identify molecular changes in the epidermal, fibroblast, and immune cells of Ovol1-deficient skin tha

71 Cardiomyocytes, fibroblasts, and endothelial cells attached well to eADF

72 different cell types including cancer cells, fibroblasts, and immune cells.

73 proteins were significantly decreased in DS fibroblasts, and in both the hippocampi and cortices of

74 re heterogeneous in cancer cells compared to fibroblasts, and it is maintained throughout the cell cy

75 f Vcan, and the migration of lung mesenchyme fibroblasts, and suggest that alveolar sac formation res

76 brain and heart mitochondria, synaptosomes, fibroblasts, and thymocytes from WT and MCU KO mice and

77 Fibroblasts are an ill-defined population consisting of

78 Instead, dermal fibroblasts are both necessary and sufficient to induce

79 at were unaffected in APCs but diminished in fibroblasts are in line with previous reports linking TL

80 g mechanisms of such selective activation of fibroblasts are not understood.

81 Recent work has revealed that fibroblasts are remarkably heterogeneous cells, but the

82 We find that embryonic meningeal fibroblasts are transcriptionally distinct between brain

83 cy (TE) of proline-rich collagens in cardiac fibroblasts as well as TGF-beta (transforming growth fac

84 ed isolated adult mouse cardiac myocytes and fibroblasts, as well as preclinical mouse models of hype

85 ant protein D (SP-D) are regulated by tissue fibroblasts at extravascular sites via an endocytic mech

86 ox state and migration using mouse embryonic fibroblast Balb/3T3, human dermal fibroblast NHDF cell l

87 functional assays in patient-derived cardiac fibroblasts based on YAP (yes-associated protein)-transc

88 tein complex at cristae junctions in patient fibroblasts bearing the CHCHD10(S59L) mutation, the role

89 arkedly upregulated miR-21 and miR-221 in RV fibroblasts but not in LV fibroblasts nor cardiomyocytes

90 of reactive oxygen species in A549 cells and fibroblasts, but fibroblasts were less affected.

91 etion of matrix proteins upon stimulation of fibroblasts by transforming growth factor-beta (TGFbeta)

92 genesis, inflammation, and cancer-associated fibroblast (CAF) activation.

93 of five TNBCs revealed two cancer-associated fibroblast (CAF) and two perivascular-like (PVL) subpopu

94 Although cancer-associated fibroblasts (CAF) are abundant in PDAC tumors, the effec

95 epithelial cells as well as cancer-activated fibroblasts (CAF) that facilitate epithelial tumor cell

96 Here, we demonstrate that cancer-associated fibroblasts (CAFs) constitute the prominent CD73(hi) pop

97 factor (FGF1) derived from cancer-associated fibroblasts (CAFs) cooperates with cancer cell-autonomou

98 Targeting cancer-associated fibroblasts (CAFs) has become an attractive goal for dia

99 nce of distinct subsets of cancer-associated fibroblasts (CAFs) in the microenvironment of murine car

100 Cancer-associated fibroblasts (CAFs) perform diverse roles and can modulat

101 ence of myofibroblast-like cancer-associated fibroblasts (CAFs).

102 OR pathway activation, secreted factors from fibroblasts can maintain this pathway in the context of

103 acted from Escherichia coli, mouse embryonic fibroblast cell cultures, and Arabidopsis thaliana leave

104 rrect the GBE1(102C>A) mutation in a primary fibroblast cell line derived from a high genetic merit h

105 -211H, NCI-H2052 and NCI-H2452 and the human fibroblast cell line MRC-5, as well as their sensitivity

106 lfate 2-O-sulfotransferase 1 in two of three fibroblast cell lines derived from affected individuals.

107 HPDL levels were significantly reduced in fibroblast cell lines derived from more severely affecte

108 ngs did not negatively impact osteoblast and fibroblast cells growth and were capable of reducing bac

109 y to characterize whole-genome expression in fibroblast cells obtained from two patients with trisomy

110 Applying OligoFISSEQ to human diploid fibroblast cells, we show how four rounds of sequencing

111 two noise components of 3975 genes in mouse fibroblast cells.

112 giogenesis, in which fibrin is contracted by fibroblast cells.

113 embedded in a reticular meshwork of red pulp fibroblasts characterized by the expression of the trans

114 HER2 therapy sensitivity is restored in the fibroblast cocultures by combination treatment with inhi

115 with selective expression of CCN1 in dermal fibroblasts (COL1A2-CCN1), display accelerated skin derm

116 al progeny are reduced in vimentin-deficient fibroblasts, compared with control cells.

117 cGMP levels in cardiac myocytes and cardiac fibroblasts, consistent with PDE10A as a cAMP/cGMP dual-

118 nalling triggered by heterotypic cancer cell-fibroblast contacts and about what activates fibroblasts

119 Experiments carried out in mouse embryonic fibroblasts corroborated these findings.

120 r suppressing Vcan in primary embryonic lung fibroblasts could, respectively, mimic or attenuate alve

121 Here, we show that fibroblasts counteract the cytotoxic effects of HER2 kin

122 d complementation studies in mouse embryonic fibroblast deficient for Esco1 and Esco2, as a means to

123 are present, including basal keratinocytes, fibroblasts, dendritic cells, and lymphocytes.

124 We designed 20 oligomers and treated fibroblasts derived from five patients to identify an ol

125 elayed entry into and exit from the Golgi in fibroblasts derived from one of the affected subjects.

126 ses of a mesenchymal niche model showed that fibroblast-derived PGE(2) drives the expansion omicronf

127 ever, the molecular mechanism by which these fibroblasts differentiate and expand is unknown.

128 Conversely, skin fibroblasts do not exhibit trained immunity, which corre

129 In patient fibroblasts, dual mRNAs encoded proteins localize in mit

130 nkara (CVA) vaccine strain in chicken embryo fibroblasts during which numerous mutations and deletion

131 These activated fibroblasts exhibit a clear profibrotic signature, expre

132 We show here that RAD50-deficient fibroblasts exhibit a marked delay in mitotic progressio

133 Human pulp fibroblasts (FP6) were used to evaluate cytotoxicity by

134 ming were also observed in the reprogramming fibroblasts from a different individual.

135 icroscopy of patient-derived lymphocytes and fibroblasts from both patients with VPS16 and VPS41 show

136 Here, we report that primary fibroblasts from DC patients and late generation telomer

137 Cs) by direct reprogramming of healthy human fibroblasts from donors of different ages and Hutchinson

138 we studied the effects of DNMT1 mutations in fibroblasts from four ADCA-DN and two HSN-IE patients.

139 e receptors for LIGHT that were expressed by fibroblasts from healthy donors or patients with active

140 Further, we demonstrate that fibroblasts from individuals with LCC are defective in r

141 d CRY expression were also observed in human fibroblasts from major depressive disorder patients.

142 ral myelin protein 22) protein and in dermal fibroblasts from patients with CMT1A, PMP22 aggregates h

143 creased SIRT7 expression in lung tissues and fibroblasts from patients with pulmonary fibrosis compar

144 lysosomes in PSEN1 Knock out (KO) cells and fibroblasts from PSEN1 familial AD patients, which resto

145 Human postmortem brain tissue and fibroblasts from subjects with DS and healthy controls w

146 e that elevated expression of CCN1 by dermal fibroblasts functions as a key mediator of dermal aging.

147 In murine fibroblasts, GRA15-mediated TRAF6 recruitment mediates t

148 Fibroblast Growth Factor (FGF) dependent signalling is f

149 The three members of the endocrine-fibroblast growth factor (FGF) family, FGF19, 21, and 23

150 show that posttranscriptional attenuation of fibroblast growth factor (FGF) signaling is essential fo

151 scriptomics, we found that components of the Fibroblast Growth Factor (FGF) signaling pathway were en

152 progenitors and myoblasts is mediated by the fibroblast growth factor (FGF) signaling pathway, and ex

153 Fibroblast growth factor (FGF) signaling plays pivotal r

154 ner cell mass and trophectoderm cells due to fibroblast growth factor (FGF) signaling.

155 ivin maintain self-renewal in the absence of fibroblast growth factor (FGF) signalling.

156 Here we show that acidic fibroblast growth factor (FGF1) derived from cancer-asso

157 evels of neurite markers betaIII tubulin and fibroblast growth factor 12, with differential effects i

158 Aldafermin, an engineered analog of fibroblast growth factor 19, inhibits bile acid synthesi

159 Using fibroblast growth factor 2 (FGF2) as a model system, we

160 s IL-1beta and IL-18, growth factors such as fibroblast growth factor 2 (FGF2), redox enzymes such as

161 epatic expression of the metabolic regulator fibroblast growth factor 21 (FGF21) was blunted by TCS.

162 ceptor gamma coactivator 1-alpha) and FGF21 (fibroblast growth factor 21).

163 e demonstrate systemic and direct effects of Fibroblast growth factor 23 (FGF23) and Klotho, which no

164 Klotho functions as a co-receptor for fibroblast growth factor 23 (FGF23) signaling, whereas i

165 The discovery of fibroblast growth factor 23 (FGF23), which revolutionize

166 How Na(V) -CaM, CaMKII and FGF/fibroblast growth factor homologous factor interactions

167 We assessed actions of fibroblast growth factor receptor (FGFR) 2 in urothelium

168 ch a conventional optogenetic design for the fibroblast growth factor receptor (FGFR).

169 (EMT), which included enhanced expression of fibroblast growth factor receptor 1 (FGFR1) and axonal g

170 Hypoxia induced increased fibroblast growth factor receptor 1 (FGFR1) expression i

171 Other anti-fibroblast growth factor receptor 3 (FGFR3) compounds ar

172 Fibroblast growth factor receptor 3 (FGFR3) was also ide

173 ions affecting insulin-like growth factor 1, fibroblast growth factor receptor and WNT signalling are

174 sstalk between Target of Rapamycin (TOR) and Fibroblast growth factor receptor b (Fgfrb) signaling in

175 mutations severely disrupt PM association of fibroblast growth factor receptor substrate 2alpha but d

176 r (VEGF), brain-derived neurotrophic factor, fibroblast growth factor-2, and ciliary neurotrophic fac

177 ercent tubular reabsorption of phosphate and fibroblast growth factor-23 (FGF23) at all CKD stages, a

178 Fibroblast growth factors (FGF) act as proangiogenic and

179 Most fibroblast growth factors (FGFs) function as receptor li

180 ed growth factor, platelet concentrates, and fibroblast-growth factor-2.

181 cell attachment activity using human dermal fibroblasts (HDFs).

182 in in human adult dermal (HDFs) and neonatal fibroblasts (HFFs) mainly via TGF-beta canonical signali

183 observed in the coculture of human gingival fibroblasts (HGFs) and U937 human monocytic cells; howev

184 olecular level, RNA sequencing of HF cardiac fibroblasts highlighted the overrepresentation of dysreg

185 n bronchial epithelial cell (BEC)/human lung fibroblast (HLF) coculture model.

186 our understanding of the different roles of fibroblasts in ECM biology, wound healing, diseases, and

187 en et al. demonstrated that highly activated fibroblasts in metastatic colorectal cancer increase tis

188 IL33 is upregulated in metastases-associated fibroblasts in mouse models of spontaneous breast cancer

189 d7 alleviated deficient ECM production in SA fibroblasts in response to TGFbeta.

190 It has recently been shown that a subset of fibroblasts in the sublining undergoes a major expansion

191 Lapatinib sensitivity was not altered by fibroblasts in tumor cells that exhibited sustained MTOR

192 inflammatory and profibrogenic responses in fibroblast (in vitro) and cardiac fibrosis in mice.

193 ssion of ATOH1 in variant MCC cell lines and fibroblasts induced miR-375 expression, whereas ATOH1 kn

194 Mechanical stimulation of fibroblasts induces changes in the actin cytoskeleton in

195 mpaired the differentiation of 3T3-L1 murine fibroblasts into adipocytes.

196 We found that rhbeta-gal uptake by the fibroblasts is dose-dependent and saturable and can be c

197 We infected primary fibroblasts isolated from domestic cats (Felis catus) an

198 successfully demonstrated the use of dermal fibroblasts isolated from DPs as models for PDK4 deficie

199 MHV68 infection of B cells, macrophages, and fibroblasts leads to robust activation of the B2 family

200 that nicotine increases NGF by reducing lung fibroblast (LF) microRNA-98 (miR-98) and PPARgamma level

201 phage-like) synoviocytes and CD44(+) type B (fibroblast-like) synoviocytes.

202 We investigated 15 patient-derived fibroblast lines and generated six lines of induced plur

203 -seq and exome-seq data from 32 human dermal fibroblast lines, identifying hundreds of differentially

204 size that purine alterations detected in LND fibroblasts may also occur in the brain of patients with

205 Moreover, PGAM5 deficient mouse embryonic fibroblasts (MEFs) exhibited decreased phosphorylation l

206 marrow-derived macrophages, mouse embryonic fibroblasts (MEFs), and human HeLa cells upon IFN stimul

207 lpha5 proteins in K41 wild-type mouse embryo fibroblasts (MEFs), CRT null MEFs were unresponsive.

208 tem cells in comparison with mouse embryonic fibroblasts (MEFs).

209 the simian virus 40 (SV40)-transformed human fibroblast model cell line used in this study.

210 hat the intrinsic geometric heterogeneity of fibroblasts modulates the nuclear mechanotransduction of

211 ntaining these vesicles appeared to increase fibroblast motility.

212 xposed simultaneously to the same substrate, fibroblasts moved at an increased speed over epithelial

213 erformed in prkar1 knock-out mouse embryonic fibroblasts, neonatal myocytes, or adult LV myocytes iso

214 embryonic fibroblast Balb/3T3, human dermal fibroblast NHDF cell lines, and on neoplastic cell lines

215 and miR-221 in RV fibroblasts but not in LV fibroblasts nor cardiomyocytes of either ventricle.

216 ed a non-integrative reprogramming of dermal fibroblasts obtained from two patients with radiographic

217 In vitro, division of primary fibroblasts occurs without Cep55 and ESCRT-III at the mi

218 pecific binding to human spleen but not lung fibroblasts of the transgenic line expressing the VIR14

219 formed ATAC-seq from bulk tissue or purified fibroblasts of uninjured and regenerating caudal fins.

220 CM genes independent of topography, but only fibroblasts on flat and randomly oriented mimetics had i

221 trated that the laterally confined growth of fibroblasts on micropatterned substrates induces stem-ce

222 vorable influence of Gremlin-1 production by fibroblasts on proliferation of malignant lung adenocarc

223 Conditional ablation of IGF1 in alveolar fibroblasts or deletion of the IGF-1 receptor from ILC p

224 1-2 mum structures in primary human foreskin fibroblasts or mouse bone marrow-derived dendritic cells

225 expression of inflammatory cytokines in oral fibroblasts, oral human squamous carcinoma cells and mac

226 their use can be limited due to the risk of fibroblast overgrowth.

227 activation and proliferation of an abnormal fibroblast phenotype that is resistant to apoptosis, deg

228 ns in collagen organization regulate cardiac fibroblast phenotype through mechanical activation of p3

229 plains the topography-dependent diversity in fibroblast phenotypes observed here.

230 Functional tests performed on HF cardiac fibroblasts pointed at mechanosensor YAP as a key player

231 owever, they did not enable cytoskeletal and fibroblast polarization; elastomers with high cross-link

232 y integrin beta1, leading to augmentation of fibroblast proliferation and matrix synthesis downstream

233 F (connective tissue growth factor), reduced fibroblast proliferation, and decreased collagen product

234 kdown significantly attenuated RV but not LV fibroblast proliferation.

235 Our data uncover mechanisms whereby stromal fibroblasts regulate cancer cell metabolism independent

236 ollectively, our results highlight efficient fibroblast rejuvenation through laterally confined repro

237 Stromal fibroblasts represent an abundant cell type in the tumor

238 al diversity of colorectal cancer-associated fibroblasts, representing a non-cell autonomous mechanis

239 ral expression of wild-type TRAPPC4 in these fibroblasts restored trafficking, suggesting that the tr

240 in tumor cells recapitulates the effects of fibroblasts resulting in sustained MTOR signaling and po

241 hough transcriptome analysis of human atrial fibroblasts reveals little change after exposure to calc

242 adenocarcinoma (PDAC) is characterized by a fibroblast-rich desmoplastic stroma.

243 ease in dermal sheath proteins in the dermal fibroblast secretome with aging.

244 Moreover, ASD fibroblasts showed overactive mitochondrial bioenergetic

245 All patient-derived fibroblasts showed reduced levels of the AP4E1 subunit,

246 She underwent cosmetic plasma fibroblast skin tightening treatment at her local salon

247 hts a possible complication following plasma fibroblast skin tightening treatment.

248 g with associated support cells that include fibroblasts, smooth muscle, macrophages and other immune

249 Inducing fibroblast-specific deletion of Txndc5 mitigates the pro

250 of canonical signaling using Sfrp1, Dkk1, or fibroblast-specific genetic ablation of beta-catenin str

251 Here, we generated fibroblast-specific inducible focal adhesion kinase (FAK

252 sponse, which is mediated by activation of a fibroblast-specific NLRP3 inflammasome and subsequent IL

253 By contrast with RAD50, fibroblast strains deficient in ATM or NBN did not show

254 otein CD26 to identify functionally distinct fibroblast subpopulations in human skin.

255 e natural compounds in primary human cardiac fibroblasts, subsequent validation, and mechanistic in v

256 Here we report switching of fibroblast subtypes from a neonatal to adult state and t

257 Fibroblast subtypes localize to discrete anatomical posi

258 on of CSF-1 and IL-34 in gingival tissue and fibroblasts suggests involvement in myeloid cell functio

259 teins was decreased in affected individuals' fibroblasts, supporting a possible disease mechanism.

260 ing fibrotic stroma rich in tumor-associated fibroblasts (TAF) is drawing increased therapeutic atten

261 at significantly higher levels by follicular fibroblasts than by interfollicular subtypes.

262 ifferentiation of perivascular and sublining fibroblasts that express CD90 (encoded by THY1).

263 prominent stroma including cancer-associated fibroblasts that express fibroblast activation protein (

264 oping skin, we identified neonatal papillary fibroblasts that form a transient regenerative cell type

265 vel, biological difference between RV and LV fibroblasts that might underlie distinctions in patholog

266 uding, adhesion and migration in EOC-derived fibroblasts that suggest the development of a malignant

267 s revealing that a small percentage of human fibroblasts that were induced to express EC markers in M

268 attenuates maladaptive responses of cardiac fibroblasts, the effector cells of fibrosis in the heart

269 uals inhibited hedgehog signaling in NIH 3T3 fibroblasts, thereby providing an underlying mechanism f

270 Finally, compounds 1-5 were tested on human fibroblasts: they are not cytotoxic and they do not acti

271 Aligned mimetics caused cardiac fibroblasts to elongate while randomly organized topogra

272 fibroblast contacts and about what activates fibroblasts to express inflammatory mediators(1,3).

273 use mammalian cell lines and proband-derived fibroblasts to further confirm the pathogenicity of vari

274 4, and MYC (OSKM) together can convert human fibroblasts to induced pluripotent stem cells (iPSCs).

275 CD147 can interact with fibroblasts to stimulate the expression of MMPs associat

276 1 increased OASIS expression coincident with fibroblast-to-myofibroblast transition and OASIS contrib

277 Upon RPM depletion, red pulp fibroblasts transiently produced the monocyte chemoattra

278 and vinculin) generated from rabbit corneal fibroblasts treated with transforming growth factor (TGF

279 cancer cell lines, primary cancer cells, and fibroblasts under unhindered growth conditions is dynami

280 een that uses coexpression analysis of human fibroblasts undergoing LTbetaR stimulation and affinity-

281 f the viscoelastic and plastic properties of fibroblasts using a protocol with stepwise increasing an

282 cluding epithelial and stromal cells such as fibroblasts, vascular, and immune cells, to spur further

283 vity of TR in both cell types, but spread in fibroblasts was impaired.

284 lysome profiling-Seq in halofuginone-treated fibroblasts, we identified multiple novel Pro-rich genes

285 ne array to determine how the dermal papilla fibroblasts were eliciting this effect and identified tw

286 n species in A549 cells and fibroblasts, but fibroblasts were less affected.

287 primary antigen-presenting cells (APCs) and fibroblasts were performed.

288 minent ultrastructural changes of the mutant fibroblasts were reduced presence of free ribosomes, the

289 Human dermal fibroblasts were used as comparator cells.

290 ng, we identify heterogeneity among adhesion fibroblasts, which is more pronounced at early timepoint

291 large T antigens induced ATOH1 expression in fibroblasts, which was paralleled by miR-375 expression

292 nchronization method for G2/M phase of sheep fibroblasts, which was successfully applied to flow-sort

293 ansfer of chromatin from swine primary fetal fibroblasts, which were edited with TALENs and single-st

294 iented mimetics had increased percentages of fibroblasts with alphaSMA stress fibers.

295 ents must be designed to target the abnormal fibroblasts with high specificity because many classes o

296 In agreement, patient fibroblasts with longer periods displayed muted circadia

297 irst, we showed that the treatment of bovine fibroblasts with UNC0638 did mitigate the levels of H3K9

298 These studies were repeated using human fibroblasts, with fluorescence-activated cell sorting an

299 racing demonstrated the epicardial origin of fibroblasts within fibro-fatty infiltrates.

300 Ascl1 and Myod1 was surprisingly similar in fibroblasts, yet their transcriptional outputs were dras