ライフサイエンスコーパス: fibroblast proliferation

1 kdown significantly attenuated RV but not LV fibroblast proliferation.

2 y synergistically inhibits FoxO3a, promoting fibroblast proliferation.

3 n, proliferation-related gene induction, and fibroblast proliferation.

4 a1 integrin signaling prevented tPA-mediated fibroblast proliferation.

5 has revealed a dose-dependent inhibition of fibroblast proliferation.

6 Polymerized type I collagen suppresses fibroblast proliferation.

7 guanosine monophosphate and inhibits cardiac fibroblast proliferation.

8 by IL-1beta-stimulated fibroblasts enhances fibroblast proliferation.

9 sical and novel PKC isozymes does not affect fibroblast proliferation.

10 The C-terminal domain of CTGF mediates fibroblast proliferation.

11 her confirmed that histamine inhibited heart fibroblast proliferation.

12 ght-driven H2O2 production and inhibition of fibroblast proliferation.

13 ith P-15 did not have any effect on gingival fibroblast proliferation.

14 d untreated root shavings inhibited gingival fibroblast proliferation.

15 gated the inhibitory effects of IFN-gamma on fibroblast proliferation.

16 rface had synergistic effects in stimulating fibroblast proliferation.

17 ibrosis-related genes in addition to cardiac fibroblast proliferation.

18 produced interferon 1 (IFN1), which inhibits fibroblast proliferation.

19 side synthesis blocked growth factor-induced fibroblast proliferation.

20 ectively bypass the requirement for c-myc in fibroblast proliferation.

21 bserved that miR-125b inhibits p53 to induce fibroblast proliferation.

22 as a downstream mediator of TGF-beta-induced fibroblast proliferation.

23 th fibroblast-bearing coils showed extensive fibroblast proliferation.

24 iated with osteoclastogenesis inhibition and fibroblast proliferation.

25 important to their synergistic effects on BM fibroblast proliferation.

26 and in synergy with either cytokine induced fibroblast proliferation.

27 tant to elucidate factors regulating cardiac fibroblast proliferation.

28 iac fibroblast-derived) adenosine on cardiac fibroblast proliferation.

29 of endogenous NO synthesis had no effect on fibroblast proliferation.

30 ophy and/or remodeling by modulating cardiac fibroblast proliferation.

31 1c+ CD11b+ CD1c- phagolysosome+) upon dermal fibroblast proliferation.

32 eta resulted in decreased CD11b- dermal cell fibroblast proliferation.

33 omeostatic restraint of primary human dermal fibroblast proliferation.

34 of CSCs in both PDAC and breast cancer, and fibroblast proliferation.

35 sed to screen secreted proteins that promote fibroblast proliferation.

36 st activation and fetal bovine serum-induced fibroblast proliferation.

37 extracellular matrix deposition, and promote fibroblast proliferation.

38 on, which was amplified primarily by cardiac fibroblast proliferation.

39 at Treg-secreted Areg functioned to increase fibroblast proliferation.

40 acrophage-derived TNF stimulates BPH-derived fibroblast proliferation.

41 ng, and decreased contractility dependent on fibroblast proliferation.

42 ased alveolar epithelial cell apoptosis, and fibroblast proliferation.

43 ed Ca(2+) entry, ERK1/2 phosphorylation, and fibroblast proliferation.

44 tion of endothelial cells, and more synovial fibroblast proliferation.

45 emonstrate central roles for LPA and LPA1 in fibroblast proliferation.

46 on indicating the essential role of STAT3 in fibroblast proliferation.

47 harmacological inhibitor of aneuploid murine fibroblast proliferation.

48 eir activation and subsequent stimulation of fibroblast proliferation.

49 atory cell adhesion and migration as well as fibroblast proliferation.

50 dent CTGF expression, which, in turn, drives fibroblast proliferation.

51 ulating Sprouty-1, a protein that suppresses fibroblast proliferation.

52 ed kinase phosphorylation inhibition reduced fibroblast proliferation.

53 bilical vein endothelial cell monolayers and fibroblast proliferation.

54 HAS3 knockdown by shRNA caused inhibition of fibroblast proliferation.

55 hairpin RNA [shRNA]) decreased canine atrial fibroblast proliferation.

56 f dominant-negative FoxO3a augmented control fibroblast proliferation.

57 enced by its enhancement of keratinocyte and fibroblast proliferation.

58 asses of gadolinium chelates stimulate human fibroblast proliferation.

59 activator (tPA) promotes renal interstitial fibroblast proliferation.

60 ferentiation, epithelial cell phenotypes and fibroblast proliferation.

61 a phosphorylation, cyclin D1 expression, and fibroblast proliferation.

62 age, cytotoxic and autoimmune responses, and fibroblast proliferation, a lesion similar to that of rh

63 , and matrix remodeling enzymes that promote fibroblast proliferation, activation, and differentiatio

64 ll-conditioned media or coculture stimulated fibroblast proliferation, activation, and myofibroblast

65 l age of an individual, where eta represents fibroblast proliferation and [Formula: see text] represe

66 udy provide optimal concentration ranges for fibroblast proliferation and a framework for understandi

67 Analysis of data suggests that increased fibroblast proliferation and a simultaneous decrease in

68 brosis (IPF) is characterized by exaggerated fibroblast proliferation and accumulation of collagens a

69 The engagement of the CCR3 receptor promoted fibroblast proliferation and activation via PI3K (phosph

70 ssue regeneration, Wnt signaling can promote fibroblast proliferation and activation, leading to fibr

71 vere endoluminal coronary injury resulted in fibroblast proliferation and adventitial remodeling.

72 IP-10 did not modulate cardiac fibroblast proliferation and apoptosis but significantly

73 The effects of BMP2 and BMP4 on corneal fibroblast proliferation and apoptosis were also examine

74 ole, the same pathway surprisingly inhibited fibroblast proliferation and cardiac hypertrophy through

75 Conversely, overexpression of FGF2 increased fibroblast proliferation and collagen deposition, accele

76 ed interstitial fibrosis in vivo and reduced fibroblast proliferation and collagen expression in vitr

77 roblast-bearing coils showed marked interval fibroblast proliferation and collagen formation.

78 K1/2 (MAPKK), and ERK1/2, on CTGF-stimulated fibroblast proliferation and collagen gel contraction wa

79 ibrotic cytokine IL-4 interact in regulating fibroblast proliferation and collagen production, and, i

80 pha expression was associated with increased fibroblast proliferation and collagen production.

81 pharmacological inhibition of c-abl reverses fibroblast proliferation and collagen synthesis to wild-

82 rosis (IPF) through its ability to stimulate fibroblast proliferation and collagen synthesis.

83 matricellular protein secretion, inhibiting fibroblast proliferation and collagen synthesis.

84 Fibrosis, as evidenced by fibroblast proliferation and connective tissue depositio

85 Endothelin-1 induces lung fibroblast proliferation and contractile activity via th

86 at MB was more effective in stimulating skin fibroblast proliferation and delaying cellular senescenc

87 OGG1 and SMAD7 interact to induce fibroblast proliferation and differentiation and display

88 Fibroblast proliferation and differentiation are central

89 Thus, fibroblast proliferation and differentiation are control

90 that in turn regulate underlying mesenchymal fibroblast proliferation and differentiation at least in

91 Moreover, HKL-treatment blocks cardiac fibroblast proliferation and differentiation to myofibro

92 gehog pathway inhibition was assayed by lung fibroblast proliferation and differentiation with and wi

93 ys remodelling at least partly by increasing fibroblast proliferation and differentiation with result

94 TRPC3 channels regulate cardiac fibroblast proliferation and differentiation, likely by

95 26 and causes TRPC3-dependent enhancement of fibroblast proliferation and differentiation.

96 PM7-mediated Ca(2+) signal for its effect on fibroblast proliferation and differentiation.

97 whereas transgenic MBNL1 expression blocked fibroblast proliferation and drove the population into a

98 hat control the timing and extent of cardiac fibroblast proliferation and ECM production are not know

99 reases epidermal growth factor (EGF)-induced fibroblast proliferation and enhances EGF receptor (EGFR

100 is is a progressive disease characterized by fibroblast proliferation and excess deposition of collag

101 educed the ability of TGF-beta1 to stimulate fibroblast proliferation and expression of alpha-smooth

102 This is accompanied by extensive fibroblast proliferation and extracellular matrix (ECM)

103 redominant source of TGF-beta1, which drives fibroblast proliferation and extracellular matrix deposi

104 embling lung developmental processes, induce fibroblast proliferation and extracellular matrix deposi

105 dministration suppressed AF while decreasing fibroblast proliferation and extracellular matrix gene e

106 activation of IL-6 trans signaling enhanced fibroblast proliferation and extracellular matrix protei

107 ed protein (LRP) in the regulation of kidney fibroblast proliferation and extracellular signal-regula

108 e pathological consequence of stress-induced fibroblast proliferation and fibroblast-to-myofibroblast

109 age, autoimmune and cytotoxic processes, and fibroblast proliferation and fibrosis.

110 les for dermal Wnt signaling/beta-catenin in fibroblast proliferation and in the epidermal hair folli

111 ed mast-cell tryptase release, which induced fibroblast proliferation and increased LAM-spheroid size

112 Although excessive fibroblast proliferation and inflammation occur when abn

113 t size, deletion of FGF2 resulted in reduced fibroblast proliferation and interstitial collagen depos

114 ognized function of vimentin in coordinating fibroblast proliferation and keratinocyte differentiatio

115 , IIGP, GTPI, IGTP, Ifi202A), stimulators of fibroblast proliferation and matrix synthesis (interleuk

116 y integrin beta1, leading to augmentation of fibroblast proliferation and matrix synthesis downstream

117 tial fibrosis, which correlated with reduced fibroblast proliferation and matrix synthesis, after nep

118 jor collagen/laminin receptor that regulates fibroblast proliferation and mesangial cell migration an

119 Functional assays showed that TRAF6 promoted fibroblast proliferation and migration as well as MMP an

120 le cell types to coordinate keratinocyte and fibroblast proliferation and migration for epidermal and

121 ystem confirmed that TSP2 depletion enhances fibroblast proliferation and migration, associated with

122 induced beta-catenin activation, stimulated fibroblast proliferation and migration, collagen gel con

123 ofibroblasts in vitro but potently inhibited fibroblast proliferation and migration.

124 negative effects mediated by PGE2 on tendon fibroblast proliferation and MMP production, which may l

125 t CTGF blockade suppressed TGF-beta1-induced fibroblast proliferation and myofibroblast differentiati

126 TRPC3 blockade or Ca(2+) removal inhibited fibroblast proliferation and myofibroblast differentiati

127 poptosis have been implicated in the rampant fibroblast proliferation and pannus formation characteri

128 n a critical role to FKN and its receptor in fibroblast proliferation and pannus formation in RA.

129 Liquid-PRF increased oral fibroblast proliferation and promoted keratinocyte migra

130 odeling genes in Tc2 cells that enhanced the fibroblast proliferation and protein production required

131 he former was manifested by increased murine fibroblast proliferation and reduced cutaneous tissue in

132 ork is required to trigger the initiation of fibroblast proliferation and restore homeostatic cellula

133 Normally, polymerized collagen suppresses fibroblast proliferation and serves as a physiological r

134 may be important for both mitogen-stimulated fibroblast proliferation and skeletal muscle cell differ

135 d regeneration after injury, and stimulating fibroblast proliferation and the production of FN and co

136 olysaccharide hyaluronan (HA) in influencing fibroblast proliferation and thereby affecting wound hea

137 y dermis, whereas S100A9 was shown to induce fibroblast proliferation and to enhance fibroblast CCN2

138 profibrotic transforming growth factor-beta, fibroblast proliferation and trans-differentiation, epit

139 nonreceptor c-abl tyrosine kinase regulates fibroblast proliferation and, by this means, is a costim

140 and this effect may be due to suppression of fibroblast proliferation and/or suppression of matrix de

141 Finally, in TACC2-deficient embryonic fibroblasts, proliferation and cell cycle progression as

142 sive disorder characterized by inflammation, fibroblast proliferation, and accumulation of extracellu

143 Ac-SDKP on monocyte/macrophage infiltration, fibroblast proliferation, and collagen deposition in the

144 lting in immune activation, vascular injury, fibroblast proliferation, and collagen deposition.

145 mechanism by which PTEN inhibits alpha-SMA, fibroblast proliferation, and collagen production.

146 F (connective tissue growth factor), reduced fibroblast proliferation, and decreased collagen product

147 cumulation of CD4 T cells, IL-13 production, fibroblast proliferation, and esophagus remodeling.

148 rdiac remodeling which involves hypertrophy, fibroblast proliferation, and extracellular matrix produ

149 ssion, activation of integrin/FAK signaling, fibroblast proliferation, and fibrosis.

150 ed in post-infarct heart, stimulates cardiac fibroblast proliferation, and is induced by the proinfla

151 Some of its functions-angiogenesis, fibroblast proliferation, and stimulation of BM progenit

152 f the diarthroidial joints, characterized by fibroblast proliferation, angiogenesis, and perivascular

153 ration-dependent manner, FCS-induced cardiac fibroblast proliferation as assessed by DNA synthesis ([

154 pocellular dermis and a deficiency in dermal fibroblast proliferation as embryos.

155 ay also have deleterious effects on gingival fibroblast proliferation as well as collagen and non-col

156 ine the effects of chlorhexidine on gingival fibroblast proliferation as well as collagen and non-col

157 acid and gadolinium trichloride) stimulated fibroblast proliferation at a concentration of 0.01 mmol

158 meglumine) produced a maximum stimulation of fibroblast proliferation at a concentration of 0.1 mmol/

159 doteridol) produced a maximum stimulation of fibroblast proliferation at a concentration of 5 mmol/L.

160 edia specifically enriched with GDF3 induced fibroblast proliferation at a high level by stimulation

161 monstrate that PGE2 can stimulate or inhibit fibroblast proliferation at clinically relevant concentr

162 etween P2 and P50 there was no difference in fibroblast proliferation at the wound site but Wnt signa

163 Results indicate that the degree of fibroblast proliferation, attenuated by extracellular ma

164 reduced Ang II-induced VSMC and adventitial fibroblast proliferation but had no effect on myoendothe

165 reated IL-5(-/-) mice were able to stimulate fibroblast proliferation but not alpha-smooth muscle act

166 rom KGF-treated subjects inhibited pulmonary fibroblast proliferation, but increased alveolar epithel

167 ast growth factors, all strong activators of fibroblast proliferation, but not by epidermal growth fa

168 onstrate that polymerized collagen represses fibroblast proliferation by a mechanism involving the fo

169 lagen suppresses G(1)/S phase transition and fibroblast proliferation by a novel mechanism involving

170 IF2alpha and reduced BeWo cell and placental fibroblast proliferation by approximately 50%.

171 l 20 amino acids of caveolin-1 in modulating fibroblast proliferation by dampening Smad signaling and

172 PRRX1 inhibition decreased human lung fibroblast proliferation by downregulating the expressio

173 on with polymerized collagen inhibits normal fibroblast proliferation by suppression of the phosphoin

174 It increases BEC and fibroblast proliferation by up-regulating TGFbeta signal

175 ch demonstrated that high fluence RL reduces fibroblast proliferation, collagen deposition, and migra

176 , and the inhibitive effects of histamine on fibroblast proliferation could be blocked by JAK3/STAT6

177 d function of the skin secondary to impaired fibroblast proliferation, decreased collagen synthesis,

178 d function of the skin secondary to impaired fibroblast proliferation, decreased collagen synthesis,

179 Fibroblast proliferation, differentiation into myofibrob

180 are present in renal fibroblasts and control fibroblast proliferation, differentiation, and activatio

181 brought much attention to the regulation of fibroblast proliferation, differentiation, extracellular

182 g preparation enhanced IGF-stimulated 3T3-L1 fibroblast proliferation, due to the presence of a co-pu

183 echanical support of the ECM also stimulates fibroblast proliferation, expands vasculature, and incre

184 lted in decreased mechanical stretch-induced fibroblast proliferation, extracellular matrix productio

185 strated that ZNF416 plays a critical role in fibroblast proliferation, extracellular matrix synthesis

186 by PPM1A-depleted epithelial cells augmented fibroblast proliferation (>50%) compared with controls.

187 ion increased collagen deposition, stem cell/fibroblast proliferation, IL6/pSTAT3, pSMAD3, and interf

188 t size but were associated with unrestrained fibroblast proliferation, impaired scar remodeling, redu

189 nective tissue growth factor (CTGF), driving fibroblast proliferation in a paracrine fashion.

190 ces a paracrine p53 response that suppresses fibroblast proliferation in associated stroma.

191 activates ERK, and promotes inflammation and fibroblast proliferation in bleomycin-induced lung injur

192 Regulation of fibroblast proliferation in cultures of myocardial cells

193 rosis than wild-type mice due to 1) enhanced fibroblast proliferation in response to growth factors (

194 on induced by SV40 large T antigen supported fibroblast proliferation in the absence of betacyto-acti

195 Fibroblast proliferation in the presence of concentratio

196 phage-CSF, or type I collagen production, or fibroblast proliferation in this culture system.

197 We discovered that myostatin stimulated fibroblast proliferation in vitro and induced its differ

198 shown that angiotensin II induces human lung fibroblast proliferation in vitro via activation of the

199 of BAL fluid (BALF) to stimulate human lung fibroblast proliferation in vitro was examined in relati

200 r epidermal growth factor potentiated Nf1+/- fibroblast proliferation in vitro, demonstrating abnorma

201 d transforming growth factor-beta-stimulated fibroblast proliferation in vitro.

202 AII to stimulate fetal and adult human lung fibroblast proliferation in vitro.

203 nhibited AAM -promoted arginase activity and fibroblast proliferation in vitro.

204 rsten isoform is key in the control of renal fibroblast proliferation in vitro.

205 Similar to Col1 expression, fibroblast proliferation increased following physiologic

206 3- and TUNEL-positive fibroblasts, decreased fibroblast proliferation, increased nuclear translocatio

207 Fibroblast proliferation induced by tPA was associated w

208 Fibroblast proliferation is an early feature of progress

209 VSMC and fibroblast proliferation is AT1 receptor-dependent, wher

210 Further studies revealed that the effect of fibroblast proliferation is biphasic, with the promitoge

211 However, how interstitial fibroblast proliferation is controlled remains ambiguous

212 e-nucleus RNA sequencing data suggested that fibroblast proliferation is mediated by paracrine signal

213 While fibroblast proliferation is necessary for hair follicle

214 pothesis that, in fibrotic gingival lesions, fibroblast proliferation is stimulated and apoptosis is

215 however, the effect of adenosine on cardiac fibroblast proliferation is unknown.

216 tPA as a mitogen that promotes interstitial fibroblast proliferation, leading to expansion of these

217 These activated T cells stimulate fibroblast proliferation, leading to fibroblast-associat

218 Extracellular ATP stimulates cardiac fibroblast proliferation, lung inflammation, and fibrosi

219 be viewed as harboring a patchwork of clonal fibroblast proliferations (micro-FAFs) with indolent gro

220 We find that ORC and ONRC inhibit fibroblast proliferation, migration and matrix contracti

221 ocesses involved in wound healing, including fibroblast proliferation, migration, adhesion, and the a

222 wth factors significantly increased gingival fibroblast proliferation, migration, and cell adhesion o

223 in vitro analyses corroborate a decrease in fibroblast proliferation, migration, and remodeling capa

224 tone deacetylase inhibitor entinostat reduce fibroblast proliferation more than the LSD1 inhibitor GS

225 Such amplification results in fibroblast proliferation, myofibroblast differentiation,

226 Significantly enhanced fibroblast proliferation observed in NCaPP-PDGF-B-treate

227 gulation may underlie the increased gingival fibroblast proliferation observed.

228 Cardiac fibroblast proliferation occurs primarily between days 7

229 for smooth muscle cells, myofibroblasts, and fibroblasts, proliferation of which is a hallmark of idi

230 However, P-15 did not enhance fibroblast proliferation on root sections.

231 ompatibility was evaluated by human gingival fibroblast proliferation on titanium surface post-cleani

232 arily involuting blood elements with minimal fibroblast proliferation or collagen formation.

233 ge in the presence of pulmonary neutrophils, fibroblast proliferation, or collagen gene expression.

234 and aFGF may contribute to angiogenesis and fibroblast proliferation, potentially independently of i

235 Overexpression of pVHL increased lung fibroblast proliferation, protein abundance of fibronect

236 olymerized type I collagen normally inhibits fibroblast proliferation, providing a physiological mech

237 lone, serve to regulate c-Jun expression and fibroblast proliferation rates.

238 Fibrosis occurs when collagen deposition and fibroblast proliferation replace healthy tissue.

239 ata demonstrate that ATP-induced adventitial fibroblast proliferation requires activation and interac

240 expression of two genes that promote tendon fibroblast proliferation: scleraxis and tenomodulin.

241 embryonic lethality, neuronal apoptosis, and fibroblast proliferation/senescence defects but not lymp

242 tegrin beta1 with PDGFRbeta and subsequently fibroblast proliferation, suggesting a role in PDGFRbeta

243 the Chaos3 background and impaired embryonic fibroblast proliferation, suggesting that ATM drug inhib

244 ntin orchestrates the healing by controlling fibroblast proliferation, TGF-beta1-Slug signaling, coll

245 ma is associated with enhanced potential for fibroblast proliferation that is related, at least in pa

246 e improvements in keratinocyte migration and fibroblast proliferation the results from 3D models indi

247 both Xenopus oocyte maturation and mammalian fibroblast proliferation, the underlying mechanisms resp

248 ated that TGF-beta1 inhibited murine cardiac fibroblast proliferation; these antiproliferative effect

249 Fibroblast proliferation, thought to play a central role

250 a potent mitogen that promotes interstitial fibroblast proliferation through a cascade of signaling

251 l 20 amino acids of caveolin-1 in modulating fibroblast proliferation through dampening Smad signalin

252 In conclusion, gangliosides promote fibroblast proliferation through enhancement of growth f

253 ent mitogen that promotes renal interstitial fibroblast proliferation through LDL receptor-related pr

254 summary, HA facilitates TGF-beta1-dependent fibroblast proliferation through promoting interaction b

255 agonists may have a role in pulmonary artery fibroblast proliferation to hypoxia.

256 2 expression in the absence of GILT restores fibroblast proliferation to wild-type levels.

257 Furthermore, NRK-49F fibroblast proliferation triggered by conditioned media

258 t the fibrogenic niche autonomously promotes fibroblast proliferation, tubular injury, macrophage act

259 he relationship between c-myc expression and fibroblast proliferation using a c-myc antisense oligonu

260 ibroblast-derived adenosine inhibits cardiac fibroblast proliferation via activation of A2B receptors

261 integrin-mediated signaling pathway promotes fibroblast proliferation via FoxO3a suppression.

262 UPAR-/- fibroblast proliferation was 60% inhibited by an ERK kin

263 Lung fibroblast proliferation was analyzed using the Quick Ce

264 Fibroblast proliferation was determined by ELISA which m

265 The selective action of glutamine on fibroblast proliferation was determined by labeling cult

266 gery were mixed with autologous T cells, and fibroblast proliferation was determined.

267 ing intact Agtr1a) were infused with Ang II, fibroblast proliferation was found equally in these card

268 No effect on fibroblast proliferation was found in the presence of il

269 rol animals and demonstrated that peritoneal fibroblast proliferation was highly LPA1 dependent.

270 fibroblasts from an additional patient, and fibroblast proliferation was inhibited by BRAF-specific

271 Enhanced uPAR-/- fibroblast proliferation was reversed by a recombinant n

272 was added to the medium (292 micrograms/ml) fibroblast proliferation was stimulated, and by 5-6 days

273 postmitotic cell proliferation and enhances fibroblast proliferation, whereas overexpressing miR-24

274 fibroblasts by inducing capillary growth and fibroblast proliferation, which secondarily support grea

275 d activation with interstitial inflammation, fibroblast proliferation with extracellular matrix colla

276 bFGF significantly stimulated gingival fibroblast proliferation with or without heparin.

277 evious studies have implicated inhibition of fibroblast proliferation with polymerized collagen-media