ライフサイエンスコーパス: fibroblastic

1 formed from two cell lineages, myogenic and fibroblastic.

2 ne serum, to cause the keratocytes to become fibroblastic.

3 re aggressive, less differentiated, and more fibroblastic.

4 mas included one secretory meningioma and 11 fibroblastic, 11 transitional, 14 meningothelial, and tw

5 minant isoform, was ectopically expressed in fibroblastic 3T3-L1 pre-adipocytes that normally lack th

6 Fibroblastic 3T3-L1 progenitor cells expressed very low

7 tified in our study, may explain some of the fibroblastic abnormalities previously observed in patien

8 tain all the bone-marrow colony-forming-unit fibroblastic activity and can be propagated as non-adher

9 a product, tenv could induce cytotoxicity to fibroblastic and B-lymphoid cells but not to T-lymphoid

10 o their release is the ablation of VCAM-1 by fibroblastic and by endothelial cells.

11 l populations were identified: inflammatory, fibroblastic and endocardial cells.

12 Similar behavior was observed not only with fibroblastic and epithelial cell lines but also explants

13 in a nesprin protein of the LINC complex of fibroblastic and epithelial cells in culture.

14 challenge and differential diagnoses include fibroblastic and histiocytic neoplasm.

15 hematopoietic regulatory genes spanning new fibroblastic and osteoblastic subpopulations including d

16 We showed that these cells become fibroblastic and scattered, with increased N-cadherin ex

17 Reticular fibroblastic and vascular stromal cells, important for s

18 in vitro, keratocytes proliferate, becoming fibroblastic, and lose biosynthesis of unique corneal ma

19 s cultured in 10% FBS proliferated, appeared fibroblastic, and synthesized only 9% of the total glyco

20 The colony-forming unit-fibroblastic assay was used for MSC enumeration.

21 Nestin is expressed in several fibroblastic but not epithelioid cell lines.

22 te that primary cultures of keratocytes made fibroblastic by exposure to serum can return to their ke

23 d passage were transformed and designated as fibroblastic CECs (fCECs).

24 a signaling in the cancer-associated stromal fibroblastic cell compartment.

25 orneal stroma with the appropriate number of fibroblastic cell layers and Descemet's membrane of appr

26 teoblastic cell line (MC3T3-E1), and a mouse fibroblastic cell line (NIH3T3).

27 id progenitor cell line K562, and the murine fibroblastic cell line NIH 3T3.

28 ism in the embryo itself, we derived primary fibroblastic cell lines from foetuses affected by NTDs a

29 of myosin VI at the Golgi complex, immortal fibroblastic cell lines of Snell's waltzer mice lacking

30 but not in the endothelial, hemolymphoid, or fibroblastic cell lines tested.

31 arget, equine macrophages, permissive equine fibroblastic cell lines, and an engineered mouse cell li

32 , PYK2 increases actin polymerization at the fibroblastic cell periphery.

33 stromal interleukin-1beta signaling between fibroblastic cell populations.

34 Alphavirus infection of fibroblastic cell types in vitro inhibits host cell tran

35 now show that for some melanoma, sarcoma, or fibroblastic cell types that survive without integrin-me

36 It remains unknown how myogenic and fibroblastic cell-cell interactions affect cell fate det

37 litate relevant studies of cancer-associated fibroblastic cell/cholangiocarcinoma cell interactions t

38 ells from OC-activated livers yield Thy-1(+) fibroblastic cells and a population of E-cadherin(+) mes

39 Adhesions between fibroblastic cells and extracellular matrix have been st

40 genic capacity to stimulate the migration of fibroblastic cells and promote their ability to secrete

41 totic effects of lipopolysaccharide (LPS) on fibroblastic cells and to investigate the role that the

42 Since fibroblastic cells are not targets of BCR-ABL-induced on

43 Expression of wild-type INO80 in patients' fibroblastic cells corrected their hypersensitivity to h

44 e mechanisms through which cancer-associated fibroblastic cells crosstalk with cholangiocarcinoma cel

45 eractive pathways by which cancer-associated fibroblastic cells crosstalk with cholangiocarcinoma cel

46 Fibroblastic cells derived from embryonic stem cells car

47 Fibroblastic cells expressing mouse or human TIM-3 bound

48 , control DCs and IL-4-transduced T cells or fibroblastic cells failed to alter the course of the dis

49 Fibroblastic cells forced to express lefty by retroviral

50 ogenic progenitors form muscle cells whereas fibroblastic cells give rise to the supportive connectiv

51 duction of sustained transgene expression in fibroblastic cells in mice using a chimeric gene encodin

52 ooth muscle actin-positive cancer-associated fibroblastic cells in promoting intrahepatic cholangioca

53 ooth muscle actin-positive cancer-associated fibroblastic cells in the stroma of intrahepatic cholang

54 growth include interactions with myeloid and fibroblastic cells in the tumour microenvironment and on

55 en found to transform both hematopoietic and fibroblastic cells in vitro, while inducing predominantl

56 y demonstrated that LPS induces apoptosis of fibroblastic cells in vivo, largely through TNF-alpha.

57 While individual fibroblastic cells interface with a greater number of ce

58 Fibroblastic cells isolated from HF hearts are predomina

59 Whereas stroma fibroblastic cells lost the PAF-R gene expression found

60 ts revealed low to absent staining of Fas in fibroblastic cells of fibroblast foci.

61 stitutive activation of TGFbeta signaling in fibroblastic cells of mice after birth caused a marked f

62 poptosis of resident non-bone marrow-derived fibroblastic cells of the corneal stroma is strongly cor

63 al neural crest (CNC) cells give rise to the fibroblastic cells of the tongue skeletal muscle in mice

64 In contrast, fibroblastic cells or mammary tumor cells, which co-expr

65 n in the dermal layer of cell aggregates and fibroblastic cells surrounded by a pericellular matrix e

66 and associated stromal components, including fibroblastic cells that contribute to tumor growth and p

67 Myofibroblasts are fibroblastic cells that function in wound healing, tissu

68 arge number of genes that favor apoptosis of fibroblastic cells that is dependent upon activation of

69 Medium for the fibroblastic cells was replaced on day 4 with serum-free

70 Many stromal fibroblastic cells were also Gli2+.

71 astic prostate revealed that FGF7-expressing fibroblastic cells were present in higher numbers near t

72 we report that stimulation of epithelial or fibroblastic cells with G protein-coupled receptor agoni

73 In contrast, in human fibroblastic cells with inactivated p53, the SOD1 RNAi i

74 In both epithelial cells and fibroblastic cells, EEA1 and a transfected apical endoso

75 These cells include fibroblastic cells, endothelial cells, and cells of hema

76 In epithelial or fibroblastic cells, Gem or Rad expression resulted in st

77 fully functional brown fat program in naive fibroblastic cells, including skin fibroblasts from mous

78 esent in inflamed tissues and joints rich in fibroblastic cells, no significant data on fibrin(ogen)-

79 In contrast to fibroblastic cells, T or B cells expressing TIM-3 formed

80 in 14 d, compared with 28 d for age-matched fibroblastic cells.

81 asement membrane into dissociated and motile fibroblastic cells.

82 type I collagen, together with proliferating fibroblastic cells.

83 , loss of contact inhibition, and multilayer fibroblastic cells.

84 that zonal organization of osteoblastic and fibroblastic cellular phenotypes can be engineered by a

85 We differentiated fibroblastic CFU-Fs (Fibro-CFU-Fs) from mixed CFU-Fs, ba

86 fraction of Nestin(+) cells, containing most fibroblastic CFUs, mesenspheres, and self-renewal capaci

87 (low) sub-population, which possesses higher fibroblastic colony-forming units (CFUs) and mesensphere

88 After fibroblastic commitment, the ability of MSCs to differen

89 Heterotypic epithelio-fibroblastic contacts, like homotypic contacts between f

90 ation: human embryonic stem cells (hESCs), a fibroblastic differentiated derivative of the hESCs, and

91 e overload does not trigger significant EPDC fibroblastic differentiation.

92 se their keratocyte markers when they become fibroblastic during corneal wound healing.

93 Taken together, fibroblastic epigenetic changes causative of DNA damage,

94 ROCK is expressed in fibroblastic, epithelial, endothelial, and muscle cells

95 Fibroblastic expression of both uPA and uPAR were positi

96 Although patients with strong fibroblastic expression of uPA showed a tendency toward

97 Fibroblastic expression of uPAR was only related to the

98 P = 0.012; fibroblasts, P < 0.001), but only fibroblastic expression was related to the presence of i

99 to the hepatic mesenchyme where they exhibit fibroblastic features.

100 l pneumonia had a higher median profusion of fibroblastic foci (1.75 vs. 1.0, p = 0.003).

101 ance of four individual histologic features (fibroblastic foci [FF], interstitial mononuclear cell in

102 ated usual interstitial pneumonia have fewer fibroblastic foci and improved survival.

103 STAT3 was not present in alpha-SMA-positive fibroblastic foci but was observed in the nuclei of cell

104 In IPF tissue, fibroblastic foci contained cells expressing Ki67 and th

105 lung specimens of IPF, myofibroblasts within fibroblastic foci demonstrated diminished PTEN expressio

106 decrease in the number of myofibroblasts at fibroblastic foci in animals treated with SD-208 but not

107 IHC examination of fibroblastic foci in IPF lung tissue demonstrates the pr

108 eomycin-induced lung fibrosis in mice and in fibroblastic foci of human subjects with IPF, using phos

109 ning revealed increased IGF-II expression in fibroblastic foci of SSc lungs.

110 The extent of fibroblastic foci present on lung biopsy predicts surviv

111 59.42; p = 0.002 for a one-unit increase in fibroblastic foci score).

112 Profusion of fibroblastic foci was the most discriminative feature fo

113 of granulation/connective tissue deposition (fibroblastic foci).

114 Near these fibroblastic foci, an abnormal adjacency of alveolar wal

115 ty is regionally decreased in IPF within the fibroblastic foci, and that within these areas PEDF was

116 ally heterogeneous fibrosis characterized by fibroblastic foci, hyperplastic AT2 cells, and increased

117 presence of inactive FoxO3a in cells within fibroblastic foci.

118 th IPF expressed increased levels of pVHL in fibroblastic foci.

119 accumulation of fibroblasts in areas called fibroblastic foci.

120 ression are low in myofibroblasts within IPF fibroblastic foci.

121 how that these cells are concentrated within fibroblastic foci.

122 is demonstrated absent Thy-1 staining within fibroblastic foci.

123 ent 0, mild 1, moderate 2, and marked 3) for fibroblastic foci.

124 ies revealed that miR-144-3p is expressed in fibroblastic foci.

125 , we hypothesized that they would have fewer fibroblastic foci.

126 al interstitial pneumonia is the presence of fibroblastic foci.

127 ased attenuation very likely correspond with fibroblastic foci.

128 studies revealed that SHP2 was absent within fibroblastic foci.

129 CCN1 protein was predominantly localized to fibroblastic foci.

130 fibroblasts (FL-fibroblasts) in areas called fibroblastic foci.

131 rly within the fibrotic interstitium and the fibroblastic focus, and prominently within the epitheliu

132 within the epithelium directly overlying the fibroblastic focus.

133 the highly cellular perimeter region of the fibroblastic focus.

134 2 patients), telangiectatic (four patients), fibroblastic (four patients), small cell (one patient),

135 Changes in serum levels of basic fibroblastic growth factor (bFGF) were correlated with t

136 diocytes with interleukin-1 (IL-1) and basic fibroblastic growth factor (bFGF), with some induction a

137 Fibroblastic growth factor 23 (FGF23) is a circulating p

138 Fibroblastic growth factor 23 (FGF23) regulates renal ph

139 ing levels of the novel phosphaturic hormone fibroblastic growth factor 23 (FGF23).

140 Fibroblastic growth factor receptor 1 (FGFR1) signaling

141 S) are part of a wide spectrum of disordered fibroblastic growth that display striking clinical and p

142 urface mesenchymal epitopes, expressed broad fibroblastic hallmarks, and increasingly synthesized col

143 um-free medium appeared dendritic and became fibroblastic in appearance when exposed to medium contai

144 , the antagonism of the C3a receptor and the fibroblastic knockout of TLR9 similarly resulted in immu

145 Neuroblastoma-derived N2a-PK1 cells, fibroblastic LD9 cells, and CNS-derived CAD5 cells can b

146 This promotes a fibroblastic-like morphology and expression of the mesen

147 ell line, MCF-7, altered its morphology to a fibroblastic-like phenotype, which exhibited protein mar

148 -1 and vimentin, indicating that they are of fibroblastic lineage and express a well-characterized ad

149 differentiation of mesenchymal cells into a fibroblastic lineage while repressing their transformati

150 ion trajectories of vascular, monocytic, and fibroblastic lineages over regeneration, and while our d

151 While murine fibroblastic lines are comparable to human T-cell lines

152 dicted size of 37.8 kDa in neural, glial and fibroblastic lines by western blot analysis.

153 action and physiology, and downregulation of fibroblastic markers.

154 (a) alveolar collapse, (b) incorporation of fibroblastic material into alveolar walls, and (c) cigar

155 s in histogram measures of CP and CS between fibroblastic meningiomas and other subtypes were observe

156 The best model for differentiating fibroblastic meningiomas from other subtypes consisted o

157 nnate properties and modulatory roles of the fibroblastic mesenchyme.

158 altered the shape of CECs from polygonal to fibroblastic morphologies in a time- and dose-dependent

159 tumor progression, with the development of a fibroblastic morphology characteristic of metastatic cel

160 R inhibition resulted in a transition from a fibroblastic morphology to a more epithelial phenotype i

161 acteristics; i.e., change from epithelial to fibroblastic morphology, enhanced cell motility, decreas

162 1 in Madin-Darby canine kidney cells induced fibroblastic morphology, increased intercellular junctio

163 way, which induces EMT-like reprogramming to fibroblastic morphology, loss of cell polarity, contact

164 ed with changing cell shape into a flattened/fibroblastic morphology, suppression of E-cadherin expre

165 l motility; and (iv) converted epithelial to fibroblastic morphology.

166 ntrast, cells in 10% FBS developed a bipolar fibroblastic morphology.

167 in transfectants revealed a reversion from a fibroblastic, motile phenotype to a more stationary epit

168 A-null mice, suggesting that a uPA-dependent fibroblastic nAChRalpha1 pathway promotes renal fibrosis

169 the absence of RhoA and p160ROCK activity in fibroblastic NIH 3T3 cells and its presence in epithelia

170 ibute to a transition toward a senescent and fibroblastic NP cell with a limited capacity for repair.

171 ppeared dendritic on AM, even in 10% FBS but fibroblastic on plastic.

172 ocyte-specific genes to one that resembles a fibroblastic or chondroprogenitor-like pattern.

173 and most have used immortalized epithelial, fibroblastic, or hematopoietic cell lines that may not n

174 ggests that induced cells are most likely of fibroblastic origin.

175 emonstrate a lipogenic-to-myogenic switch in fibroblastic phenotype during fibrosis formation.

176 rsed the loss of differentiation markers and fibroblastic phenotype in Bcl-2-deficient chondrocytes.

177 the corneal endothelium, and they maintained fibroblastic phenotype on day 14.

178 ighly proliferative component demonstrated a fibroblastic phenotype that readily underwent myofibrobl

179 ls which expressed the transgene exhibited a fibroblastic phenotype, co-localized with sites of activ

180 ini branching, indicative of a more invasive fibroblastic phenotype.

181 cell attachment defects, and a more invasive fibroblastic phenotype.

182 e stroma of colon tumors and to cells with a fibroblastic phenotype.

183 patients do not display any TLR3-IFN-related fibroblastic phenotype.

184 of these cells to an epithelial, rather than fibroblastic, phenotype.

185 esulted in further expansion of the CD105(+) fibroblastic population and downstream SFRP1 in 3-dimens

186 Fibroblastic preadipocyte cells are recruited to differe

187 al reorganization and cell shape change from fibroblastic preadipocytes to spherical adipocytes occur

188 differed depending on whether astrocytic or fibroblastic processes were present.

189 s cultured in fetal bovine serum also become fibroblastic, proliferate, and lose these markers.

190 Fibroblastic proliferation accompanies many angiogenesis

191 nd repair process associated with persistent fibroblastic proliferation.

192 constraints, these spheroids regained their fibroblastic properties and sprouted to form 3D connecti

193 adenocarcinoma, associated with a pronounced fibroblastic reactive stroma activation surrounding pros

194 ocytic) and, to a lesser degree, peripheral (fibroblastic) regions of normal, degenerative uncalcifie

195 osthetic mesh induces a chronic foreign-body fibroblastic response creating scar tissue that imparts

196 Surgical exploration revealed a dense fibroblastic response encompassing the polypropylene mes

197 trated that Prx-2 affected a number of fetal fibroblastic responses believed to be important in media

198 Loss of the fibroblastic reticular cell (FRC) network in lymphoid ti

199 eukin (IL)-7 that is 'posted' on the stromal fibroblastic reticular cell (FRC) network on which T cel

200 The underlying structural elements of LTs, fibroblastic reticular cell (FRC) network, not only form

201 ll access to the survival factor IL-7 on the fibroblastic reticular cell (FRC) network, resulting in

202 sly showed that lymphotoxin signaling in the fibroblastic reticular cell (FRC) stromal subset was req

203 zed within networks of CD45(-)gp38(+)CD31(-) fibroblastic reticular cell (FRC)-like cells.

204 nd intravital microscopy, we showed that the fibroblastic reticular cell network regulated naive T ce

205 tial association of dendritic cells with the fibroblastic reticular cell network within lymph nodes a

206 ce the distance between intersections in the fibroblastic reticular cell network, suggesting that at

207 h T cells largely move along conduits of the fibroblastic reticular cell network, they appear to exec

208 ll responses and pathological alterations of fibroblastic reticular cell networks in the draining lym

209 CAM-1 expression, and disrupted perivascular fibroblastic reticular cell organization, the re-establi

210 Mice lacking fibroblastic reticular cell PDPN or platelet CLEC-2 exhi

211 eatment altered stromal subset, particularly fibroblastic reticular cell, production of cytokines and

212 node paracortex is composed of a network of fibroblastic reticular cells (FRC) and reticular fibers

213 infection, we demonstrate viral targeting of fibroblastic reticular cells (FRC) in the lymphoid organ

214 eled into follicles via conduits secreted by fibroblastic reticular cells (FRC).

215 on conditioning caused a loss of T-cell zone fibroblastic reticular cells (FRCs) and CCL21 expression

216 t by podoplanin (PDPN) signalling in stromal fibroblastic reticular cells (FRCs) and its modulation b

217 Fibroblastic reticular cells (FRCs) and lymphatic endoth

218 Fibroblastic reticular cells (FRCs) and their specialize

219 Fibroblastic reticular cells (FRCs) are known to inhabit

220 Fibroblastic reticular cells (FRCs) are lymphoid stromal

221 Fibroblastic reticular cells (FRCs) form a cellular netw

222 In lymph nodes, fibroblastic reticular cells (FRCs) form a collagen-base

223 that, as recently described for lymph nodes, fibroblastic reticular cells (FRCs) form a network in th

224 Fibroblastic reticular cells (FRCs) form the cellular sc

225 Fibroblastic reticular cells (FRCs) in the T cell zone o

226 At the initiation of GVHD, LN fibroblastic reticular cells (FRCs) rapidly reduced expr

227 Lymph node fibroblastic reticular cells (FRCs) respond to signals f

228 Fibroblastic reticular cells (FRCs) showed enrichment fo

229 zones are organized in a rigid 3D network of fibroblastic reticular cells (FRCs) that are a rich cyto

230 gp38(+) stromal fibroblastic reticular cells (FRCs) that express VEGF ar

231 f LN and splenic stromal cells, particularly fibroblastic reticular cells (FRCs), during experimental

232 Lymph node (LN) stromal cells, particularly fibroblastic reticular cells (FRCs), provide critical st

233 Fibroblastic reticular cells (FRCs), through their expre

234 mmunity are attributable at least in part to fibroblastic reticular cells (FRCs), which are a major p

235 We report that fibroblastic reticular cells (FRCs), which reside in the

236 also includes the lymphatic vasculature and fibroblastic reticular cells (FRCs).

237 okine Ccl19-expressing host cells, including fibroblastic reticular cells and follicular dendritic ce

238 driven by the synergistic cross-talk between fibroblastic reticular cells and interstitial flow.

239 some transgenic IL-7-Cre mice, we found that fibroblastic reticular cells and LECs strongly up-regula

240 Of the major LNSC subsets, fibroblastic reticular cells and lymphatic endothelial c

241 PN is expressed by lymphatic endothelial and fibroblastic reticular cells and promotes blood-lymph se

242 tissues, only follicular dendritic cells and fibroblastic reticular cells exhibited staining.

243 sion of adhesion molecules and chemokines by fibroblastic reticular cells most likely facilitates the

244 These stromal cells expressed markers of fibroblastic reticular cells of lymphoid organs and were

245 Fibroblastic reticular cells responded rapidly to DST by

246 s regulation occurs in the lymph node, where fibroblastic reticular cells support the maintenance of

247 a meshwork of collagen fibers ensheathed by fibroblastic reticular cells that connects the subcapsul

248 d virion attachment to CD4(-) lymphoid organ fibroblastic reticular cells that mediate transinfection

249 Fibroblastic reticular cells were flow-sorted at differe

250 dence suggests that the extensive network of fibroblastic reticular cells within the T cell areas hel

251 T (T(FH)) cells and T-B cell border-enriched fibroblastic reticular cells, is developmentally require

252 Three major types of LN SC subsets, namely fibroblastic reticular cells, lymphatic endothelial cell

253 ht the varied immunoregulatory properties of fibroblastic reticular cells, we reviewed the most recen

254 analyses demonstrated that PDPN expressed on fibroblastic reticular cells, which surround HEVs, funct

255 , CXCL12, CCL5, CCL21 and IL-6 expression in fibroblastic reticular cells.

256 idered to be derived mainly from T-cell zone fibroblastic reticular cells.

257 (-) stromal cells, a profile associated with fibroblastic reticular cells.

258 ritic cells, follicular dendritic cells, and fibroblastic reticular cells.

259 of lymph node vasculature, expansion of the fibroblastic reticular network and maintenance of lympho

260 steoblastic ROS17/2.8 cells) or inactive (in fibroblastic ROS24/1 cells) using chromatin immunoprecip

261 105 neutralizing antibody, TRC105, inhibited fibroblastic SFRP1 expression and epithelial neuroendocr

262 ated that murine keratocytes also acquired a fibroblastic shape and lost keratocan expression after f

263 acquisition correlated with transition to a fibroblastic spindle shape, assembly of actin stress fib

264 l proliferation at low doses and induced the fibroblastic spindle-shape and express alpha-sm actin at

265 included cell proliferation, adoption of a "fibroblastic" spindle-shaped morphology associated with

266 In summary, tumors form their fibroblastic stroma predominantly from precursors presen

267 basal or PTH-stimulated RANKL expression in fibroblastic stromal cell models.

268 Notch signaling, we identified Ccl19-Cre(+) fibroblastic stromal cells as critical sources of Delta-

269 een studied extensively, the contribution of fibroblastic stromal cells as portals of entry into the

270 requirement for RANKL gene transcription in fibroblastic stromal cells but may enhance responsivenes

271 Thus, Wt1(+) mesothelial and fibroblastic stromal cells constitute essential niche co

272 Activated meningeal fibroblastic stromal cells have the capacity to rapidly

273 we have uncovered a pathogenic function for fibroblastic stromal cells in alloimmune reactivity that

274 , and the role of Notch ligands expressed by fibroblastic stromal cells in alloimmunity.

275 to relapse are harbored in association with fibroblastic stromal cells in the bone marrow.

276 macrophages were induced by mesothelial and fibroblastic stromal cells that express the transcriptio

277 inactivation of Dll1 and Dll4 in subsets of fibroblastic stromal cells that were derived from chemok

278 ne (C-X-C motif) ligand 13 in epithelial and fibroblastic stromal cells that, in turn, is pivotal for

279 Here, we used liver fibroblastic stromal cells to mimic the liver microenvir

280 ipheral T cells or Notch ligands on putative fibroblastic stromal cells, we show that Notch signaling

281 ptor activator of NFkappaB ligand (RANKL) by fibroblastic stromal cells, which some evidence suggests

282 nt interactions with Notch ligand-expressing fibroblastic stromal cells.

283 GF-overexpressing tumors exhibited extensive fibroblastic stromal content, a clinical feature called

284 two-branched differentiation pathway of five fibroblastic subtypes was predicted using SLICE.

285 ulation of tumour-stromal cross-talk through fibroblastic TGF-beta pathway may depend on fibroblast p

286 To determine the role of fibroblastic TGF-beta pathway on breast cancer cells, we

287 ment of a novel, inducible, conditional, and fibroblastic TGF-beta type II receptor knockout (Tgfbr2(

288 Consistent with elevated fibroblastic TGF-beta3, fmod(-/-) fibroblasts were signi

289 n in four (100%) telangiectatic, three (75%) fibroblastic, three (25%) chondroblastic, three (6%) con

290 RNA gene knockdown in MCF-7 cells triggered fibroblastic transformation and cell invasion, resulting

291 lial cells, which may promote mesothelial to fibroblastic transition (MFT) in an NLRP3-dependent mann

292 e process of asbestos-induced mesothelial to fibroblastic transition and its amelioration in caspase-

293 suggest that asbestos induces mesothelial to fibroblastic transition in an inflammasome-dependent man

294 xperiments, we found that asbestos induces a fibroblastic transition of mesothelial cells with a gain

295 lts demonstrate that hUC-MSCs do not promote fibroblastic tumor growth and neither do they prevent tu

296 wth and immune rejection of engineered human fibroblastic tumors was not altered by the injection of

297 immunophenotyping, we studied a group of 59 fibroblastic tumors with variable protein expression pat

298 Initial diagnosis was fibroblastic tumour.

299 that dendritic cells can stimulate increased fibroblastic VEGF, suggesting the scenario that lymph no

300 cts when high TGF-beta3 levels disrupt early fibroblastic wound ingress.