ライフサイエンスコーパス: fidelity

1 e mode, which therefore did not limit coding fidelity.

2 enome-editing applications that require high fidelity.

3 is fundamental to maintaining translational fidelity.

4 n order to quantify individual foraging site fidelity.

5 ermionic atoms in the ground state with high fidelity.

6 the Cramer-Rao lower bound and uncompromised fidelity.

7 d their link to temperature independent RdRp fidelity.

8 ation encoded in the pulse signals with high fidelity.

9 additional concepts of importance to signal fidelity.

10 ion, strict migratory patterns and high site fidelity.

11 low and fast FM correlated with place-coding fidelity.

12 crease scouting productivity, data scale and fidelity.

13 epigenetically and is essential for mitotic fidelity.

14 ded their journeys to maintain foraging site fidelity.

15 localization to centrosomes ensures mitotic fidelity.

16 genetic circuits, with significantly higher fidelity.

17 AUG codons, demonstrating its importance for fidelity.

18 e experimental kinetics data with increasing fidelity.

19 aring, spanning a wide range of place-coding fidelity.

20 bsequent disruption of viral replication and fidelity.

21 ects of RNH misfolding and assist in folding fidelity.

22 examine the mechanistic basis for polymerase fidelity.

23 ion essential for translational accuracy and fidelity.

24 justments necessary to achieve high splicing fidelity.

25 use to produce a Bell state with 78 per cent fidelity.

26 ivision, the genome must be copied with high fidelity.

27 ubule attachments, thereby promoting mitotic fidelity.

28 ion require continual surveillance to insure fidelity.

29 utpeforms two-photon microscopy in recording fidelity.

30 olition readout of the ion's spin with 94.6% fidelity.

31 are important for the maintenance of enzyme fidelity.

32 A binding affinity and the base substitution fidelity.

33 ndamental mechanism ensuring DNA replication fidelity.

34 of U2AF2 along mRNAs and impact on splicing fidelity.

35 ogenesis with an in-vivo-like spatiotemporal fidelity.

36 d water yields predicted THg yield with high fidelity.

37 re length, influences chromosome segregation fidelity.

38 recording location to likely improve signal fidelity.

39 the printing process, which may impair shape fidelity.

40 known whether correlated noise limits coding fidelity.

41 are required for Las1 nuclease activity and fidelity.

42 cific silencing mechanisms to ensure lineage fidelity.

43 frames also led to a significant increase in fidelity.

44 d thousands of gene-length fragments at >20% fidelity.

45 formation about DNA polymerase catalysis and fidelity.

46 ad quantum information with a high degree of fidelity.

47 functions without compromising translational fidelity.

48 ed base substitution and frameshift deletion fidelities.

49 r ions in specific internal states with high fidelities.

50 d system to learn surgical context with high fidelity?

51 Here, we present a high-fidelity 3-year record of washover evolution and overwas

52 ncing(1,2) with continuous long-read or high-fidelity(3) sequencing data.

53 High-fidelity, 3D computational models of human lungs, scaled

54 ethylation landscape is maintained with high fidelity - a concept we term epigenetic homeostasis.

55 This results in an increase in fidelity against these specific misincorporations.

56 sis for differences in replication rates and fidelity among different viruses by generating chimeric

57 fast throughput, and more importantly, high fidelity and accuracy in MFA.

58 es of a potential positive link between mate fidelity and adult demographic rates have been comparati

59 enhanced memory strength but reduced memory fidelity and behavioral flexibility.

60 mlessly integrated, and 3D printed with high fidelity and consistency across all groups.

61 nt and the WT enzyme extended to translation fidelity and gene expression patterns in DNA damage resp

62 -seq platforms are needed that are both high fidelity and high throughput.

63 sly unappreciated differences in replication fidelity and mutagenesis.

64 uence patterns of reproductive pairing, site fidelity and personal breeding experience influence the

65 In addition, site fidelity and personal breeding experience was associated

66 Experiments designed to evaluate the fidelity and predictive power of the computational model

67 ty, but also it is involved in transcription fidelity and proofreading.

68 address how the OCM metabolites regulate the fidelity and rate of translation initiation in bacteria

69 ase) activities, responsible for replication fidelity and RNA cap G-N-7 methylation, respectively.

70 actuators, with an eye toward improving the fidelity and robustness of the printing process.

71 ut are limited by the designability, length, fidelity and scale of the input DNA.

72 However, concerns were raised on the fidelity and sensitivity of RFP-to-GFP switch of this mo

73 These findings confirm the fidelity and sensitivity of the EMT lineage tracing (Tri

74 t-generation bioinks need to have high print fidelity and should provide a biocompatible microenviron

75 leus, suggesting implications for DNA repair fidelity and subsequent cell fate.

76 We also identified that fidelity and time spent at bait sites by wild pigs was n

77 denitis suppurativa (HS) display issues with fidelity and validity to human disease.

78 ness costs of mutations that disrupt meiotic fidelity and, in some circumstances, can even make such

79 each, intraspecies pervasiveness, stability, fidelity, and attentional funnelling in social learning.

80 We aimed to assess feasibility, fidelity, and clinical outcomes of a model of midwifery

81 el arrays with sub-micron feature size, high fidelity, and high post-patterning device performance.

82 physicochemical parameters influencing shape fidelity are discussed, together with their importance i

83 ficient training of these networks using the fidelity as a cost function, providing both classical an

84 We conducted an in-depth fidelity assessment on a subsample of Health Check consu

85 nd low return of audiotapes by practices for fidelity assessment.

86 by mobile monitoring show a loss of spatial fidelity at spatial aggregations greater than 100 m.

87 High-fidelity automated flow chemistry is an alternative for

88 tively, these analyses revealed a remarkable fidelity between human characteristics of sclerosteosis/

89 are thought to account for high replication fidelity, but prior studies were adversely affected by m

90 The HP protects genome fidelity by regulating cell growth and apoptosis in resp

91 nding of the catalytic Mg(2+) contributes to fidelity by sampling the correctly aligned substrate wit

92 -nucleotide anticodon, influence translation fidelity by stabilizing the tRNA to allow for accurate r

93 of histones, which maintains transcriptional fidelity by suppressing spurious transcription.

94 ed categories were not encoded with the same fidelity by these distinct spectral components.

95 icrobial species, evidence that reduced aaRS fidelity can be adaptive is limited.

96 A, we performed kinetic analyses on the high-fidelity (Cas9-HF1) and hyper-accurate (HypaCas9) engine

97 (1-10 s) are the temporal signature of a low fidelity catalytic pathway.

98 unexpected, eukaryotic specific and dynamic fidelity checkpoint implemented by eIF5B in concert with

99 programmed DNA elimination encompasses high-fidelity chromosomal breaks and loss of specific genome

100 conserved molecular motors required for high-fidelity chromosome segregation, but their specific cont

101 and tissue, respectively, allowing for high-fidelity comparisons across biogeographic sites.

102 These factors affect assembly continuity and fidelity, complicating discrimination of genomes from co

103 netic and chemogenetic tools that allow high-fidelity control of neuronal activity in preclinical mod

104 s with solid-state defects will require high-fidelity control over multiple defects with nanoscale se

105 Combining long coherence and high-fidelity control with optical initialization and readout

106 This fidelity could not be achieved with either RBD or S2 alo

107 h 1) significantly reduce the number of high-fidelity datasets required to achieve a given level of a

108 self-propelled Voronoi model reveal that the fidelity decreases with tau/tau(D), a result that is rep

109 tions in translational initiation factors in fidelity-determining regions that contact the initiator

110 e established that PRCD is required for high fidelity disc morphogenesis, its precise role in this pr

111 rmational dynamics in specificity for a high-fidelity DNA polymerase responsible for genome replicati

112 tion terminator, but not by a host-like high fidelity DNA polymerase.

113 nslesion DNA synthesis (TLS) mediated by low-fidelity DNA polymerases is an essential cellular mechan

114 h the kinetic and mechanistic basis for high-fidelity DNA replication.

115 how perfect data recovery from low synthesis fidelity DNA.

116 thetic lethality in tumors with loss of high-fidelity double-strand break homologous recombination.

117 ificity and affect the coding efficiency and fidelity during gene replication.

118 e also uncover the features that impose high fidelity during the nucleotide-incorporation step and th

119 To understand the structural origin of the fidelity enhancement, we find that N260, located in the

120 s with very high complementary DNA synthesis fidelities, even in the absence of proofreading.

121 ingle-qubit and two-qubit control gates with fidelities exceeding 97%.

122 clean up the motor noise resulting from low-fidelity explicit strategy during motor learning.

123 ical studies are often used to estimate high-fidelity flow patterns through the large conducting airw

124 ical decoupling sequences that preserve high fidelity for long time scales.

125 s with plasmids, including three clades with fidelity for plasmid incompatibility groups H, F or X.

126 A high-fidelity, fully-coupled radiation transport and fluid dy

127 We further propose that some of the fidelity functions of 53BP1 coevolved with class switch

128 t baseline, HFpEF exhibits enhanced coupling fidelity, further aggravated by a reduction in beta-adre

129 ion and single-shot readout with conditional fidelity greater than 95 per cent.

130 CDDR can discriminate between high-fidelity (HF) and error-prone non-homologous end-joining

131 esions in the template strand cause the high-fidelity (HiFi) DNA polymerase (Pol) to stall.

132 We describe a new technique, high fidelity Imaging Retinal Densitometry (IRD), which probe

133 his nonparametric approach not only enhances fidelity in describing nonlinear growth scenarios but al

134 LCs and BCs is essential to maintain lineage fidelity in glandular epithelial stem cells.

135 n the proposed LUXE experiment, showing high fidelity in identifying distinctive features such as Com

136 rt fertility and maintain health and genetic fidelity in offspring.

137 This monosynaptic transmission exhibits high fidelity in response to repetitive OSN input.

138 Controlling efficiency and fidelity in the early stage of mitochondrial DNA transcr

139 time experimentally, the importance of site fidelity in the maintenance of large mammal home ranges

140 domain multiplexing technique, allowing high-fidelity initialization and single-shot spin measurement

141 f habitat preference (occurrence, abundance, fidelity, inter-seasonal variance and age) and performan

142 ent kinetics across the central retina, high fidelity IRD provides a unique insight into outer retina

143 c transcriptional programming with exquisite fidelity is essential for normal development.

144 their reproductive lifespan, DNA methylation fidelity is lost at a number of CpG islands (CGIs) resul

145 In the hippocampal circuitry, detection fidelity is thought to depend on the GABAergic synaptic

146 are important, but their relative impact on fidelity is unknown.

147 ability of Floquet polaritons to distil high-fidelity Laughlin states of photons outside the cavity.

148 of other reverse transcriptases with higher fidelity like AMV-RT, the methylation could either retai

149 Strong site fidelity likely drove sage-grouse to continue nesting in

150 s DNA accessibility artefacts to ensure high-fidelity mapping of the antibody-targeted protein and im

151 tes, and thus capable of contributing to the fidelity mechanism.

152 However, understanding their fidelity, mechanisms and cleavage outcomes requires syst

153 uced from cyclic olefin copolymer using high-fidelity microfabrication, as templates for colorimetric

154 of research in ageing and ALS requires high fidelity models to better recapitulate age-related human

155 While these simulations provide high-fidelity models, they are poorly suited for inference an

156 performance characteristics needed for high fidelity molecular inactivation, we have designed and sy

157 can perform real-time, continuous, and high-fidelity monitoring of a range of vital biophysical and

158 To ensure fidelity, multiple aaRSs developed editing functions tha

159 Streptococcus canis Cas9-Sc(++) and a higher-fidelity mutant HiFi-Sc(++)-that have simultaneously bro

160 We tested the fidelities of error prone tobacco organelle DNA polymera

161 ntrol of two qubits and measure single-qubit fidelities of up to 99.3 per cent.

162 generation between remote nodes with a high fidelity of 90%.

163 nd that it is feasible to set up and achieve fidelity of a model of midwifery continuity of care link

164 in mRNA decoding by increasing the rate and fidelity of aa-tRNA selection at each mRNA codon.

165 ressions, we can predict the conductance and fidelity of any QDC characterized by (N, sigma(epsilon))

166 lation initiation, RbfA and IF3 maintain the fidelity of bacterial protein synthesis.

167 Recent improvements in the fidelity of biogeochemical models translate into lower e

168 tering, provides a novel mechanism to ensure fidelity of channel localization to nodes.

169 e of tumour-derived cohesin mutations in the fidelity of chromosome segregation and aneuploidy.

170 tores Mad1 accumulation at kinetochores, the fidelity of chromosome segregation, and genome stability

171 y-dynein module during mitosis to ensure the fidelity of chromosome segregation.

172 point (SAC), a signaling network that guards fidelity of chromosome segregation.

173 ations of SRP activity are essential for the fidelity of cotranslational protein targeting.

174 d slow expression in brain tissue limits the fidelity of dendritic spine analysis and other indispens

175 alysis by many enzymes and contribute to the fidelity of DNA polymerases through a two-metal ion mech

176 ural organization of substrate maximizes the fidelity of DNA repair.

177 In doing so, they play an important role in fidelity of DNA replication and repair.

178 al quench methods show that the kinetics and fidelity of DNA replication catalyzed by the labeled enz

179 y that allows monitoring of the kinetics and fidelity of DNA synthesis through 20,000 sequences compr

180 Fidelity of DSB repair is best achieved by recombination

181 al previously unrecognized links between the fidelity of ecologically relevant object representations

182 Here we analyze the fidelity of encoding and decoding global motion in a nat

183 A central role for confidence in shaping the fidelity of evidence accumulation indicates that metacog

184 The volume and fidelity of experimental, computational, and visualizati

185 The low fidelity of foot-and-mouth disease virus (FMDV) RNA-depe

186 ilter to periodic inputs and can enhance the fidelity of information processing.

187 We found that the fidelity of inhomogeneous N-QDCs with the standard devia

188 teins at the cell surface that influence the fidelity of insulin release.

189 The fidelity of intracellular signaling hinges on the organi

190 Thus, loss of fidelity of mitochondrial morphology and segregation is

191 Maintaining the fidelity of nascent peptide chain (NP) synthesis is esse

192 The calculated fidelity of NS5B ranges between 10(-4)-10(-9) for differ

193 e to correct), but little is known about the fidelity of NS5B.

194 y Escherichia coli RNAP without altering the fidelity of nucleotide incorporation.

195 We demonstrate fidelity of our mrdna framework through direct compariso

196 may elevate fitness by ensuring the product fidelity of packaging reactions.

197 Here, we show that the fidelity of patterns to demix tissue cells depends on th

198 ociated mutations trigger a reduction in the fidelity of PDE compartmentalization.

199 contradiction to this model, defects in the fidelity of Polepsilon have a much weaker impact on muta

200 hich may serve to increase both the rate and fidelity of protein synthesis at the expense of GTP hydr

201 The fidelity of quantum transport is defined as the transmis

202 Thus, the fidelity of RNA polymerization should be considered a ma

203 20, M392, K375, and R376, contributes to the fidelity of RNA synthesis and to efficient sexual RNA re

204 l phenotypes, consistent with changes in the fidelity of RNA synthesis.

205 We also discovered that the extent and fidelity of sequence similarities between tutors and pup

206 Kinase specificity is crucial to the fidelity of signaling pathways, yet many pathways use th

207 RPBs at the ribosome exit site enhances the fidelity of substrate selection into individual protein

208 mino acids are important for maintaining the fidelity of the FMDV polymerase and ensuring faithful re

209 atch extension activity modulate the overall fidelity of the hPolepsilon holoenzyme by up to 3 orders

210 bility, recruitment and attrition rates, and fidelity of the model.

211 s required to maintain nuclear shape and the fidelity of the nuclear envelope and lamina.

212 What is the fidelity of the reaction?

213 mouse pluripotent stem cells, improving the fidelity of the resulting cells through unbiased, easy-t

214 ically tune translation rates while ensuring fidelity of the resulting protein products.

215 k for the perimetrist to improve the overall fidelity of the test result.

216 f FMDV, we propose that the lower polymerase fidelity of the type O FMDV could contribute to its domi

217 ce and provide a framework for assessing the fidelity of their implementation.

218 lternative mechanisms for maintaining a high fidelity of transcription and for RNAP arrest prevention

219 we develop an assay to measure the combined fidelity of transcription and reverse transcription.

220 Modulation of the fidelity of translation initiation by OCM opens new aven

221 noacyl-tRNA synthetases (aaRSs) dictates the fidelity of translation.

222 that algorithmic management can maintain the fidelity of video-based diagnostics in the face of missi

223 ntenance of faithful RNA synthesis activity (fidelity) of FMDV 3D(pol), suggesting that the role of t

224 of-principle experiment, we demonstrate high-fidelity operation that effectively enables quantum comm

225 ubits) require long coherence times and high-fidelity operations(1).

226 phy to definitively assess the teleportation fidelity, our data are consistent with conditional telep

227 tion of nucleoside analogs, conferring a low fidelity phenotype of the enzyme.

228 the same tumor enables the inference of high-fidelity phylogenies that form the input to many importa

229 -cell sequencing experiments that yield high-fidelity phylogenies, which will improve downstream anal

230 o acid substitution FMDV variant with a high-fidelity polymerase associated with viral fitness, virul

231 lowed by a discussion on error-prone and low-fidelity polymerases and their impact on viral diversity

232 NA viruses replicate their genomes with high-fidelity polymerases that rarely make base substitution

233 y rule was introduced by promising that high-fidelity predictions of recovery following stroke were b

234 problems, we show that DDxNet produces high-fidelity predictive models, and sometimes even provides

235 ynamic-clamp experiments revealed that spike fidelity primarily depended on changes in presynaptic de

236 We demonstrate high-fidelity projective readout and control of the nuclear s

237 A crucial component of these systems is high-fidelity, projective measurement of the spin state.

238 Coulomb interacting regime relevant for high-fidelity quantum computation to strongly coupled donor a

239 Trapped atomic ions form the basis of high-fidelity quantum information processors(5,6) and high-ac

240 equiring a combination of efficient and high-fidelity quantum memories, gate operations, and measurem

241 graph alongside OM scaffolds to produce high-fidelity reconstructions.

242 -aspect ratio graphene offers gel-free, high-fidelity recording of muscle activities.

243 y its mechanisms for substrate binding and a fidelity-related conformational change referred to as "f

244 ays, specialized mechanisms that ensure high-fidelity replication, chromosome segregation, and repair

245 nisms affected by strong nucleosomes are low-fidelity replication, insufficient mismatch repair and i

246 olzeta) belongs to the same B-family as high-fidelity replicative polymerases, yet is specialized for

247 With this framework we are able to get high fidelity results (1% error rate), without human interven

248 iruses encode a proof-reading deficient, low-fidelity RNA-dependent polymerase (RdRp), which generate

249 Using this system, we identified enhanced-fidelity SaCas9 (efSaCas9) (variant Mut268 harboring the

250 sphate is incorporated by the relatively low fidelity SARS-CoV and SARS-CoV-2 RNA-dependent RNA polym

251 f our technique, we apply the UMI-based high-fidelity sequencing protocol to eliminate sequencing err

252 reocontrolled mechanical properties and high-fidelity shape memory behaviour.

253 ically regulated in vivo to enhance synaptic fidelity.SIGNIFICANCE STATEMENT Homeostatic mechanisms i

254 the UBP is replicated with an efficiency and fidelity similar to that of natural DNA and sufficient f

255 We used high-fidelity simulations, coupled with synchrotron experimen

256 rent optical and spin manipulation, and high-fidelity single-shot optical readout of the hyperfine sp

257 (abnormality detection/phenotyping) and data fidelity (single-lead ECG/22-channel EEG).

258 roblem by sampling the QAOA output with high-fidelity, single-shot, individual qubit measurements.

259 , some individuals show higher foraging site fidelity (spatial specialization) than others.

260 ctical ground truth, CNNs produced high data fidelity (SSIM = 0.94 +/- 0.02, NRMSE = 2.8% +/- 0.4) an

261 l potentials that balances scalability, high-fidelity state preparation, site-resolved readout and pr

262 eins provides the ultimate paradigm for high-fidelity synthesis of long polymers of defined sequence

263 RNA polymerases (RdRPs) have low replication fidelity that is essential for viral fitness and evoluti

264 may be responsible for aiding in maintaining fidelity (the frequency of incorrect incorporation event

265 nd its gene family are key regulators of DNA fidelity through diverse roles in double-strand break re

266 ld be explained by benefits afforded by mate fidelity to adult vital rates.

267 Data from FreeHi-C exhibit high fidelity to biological Hi-C data.

268 line tau tracer retention showed the highest fidelity to clinical phenotype, supporting the important

269 atomically accurate angiograms, with similar fidelity to FA images, and significantly outperforms two

270 tructured RNAs with high efficiency and high fidelity to maintain genetic information across successi

271 e particle-gas concentration ratio with more fidelity to measurements than equilibrium models.

272 se changes on the range of species that show fidelity to migratory destinations, as philopatry is hyp

273 lymerases to fine-tune replication rates and fidelity to optimize virus fitness.

274 aborative skills, fairness expectations, and fidelity to social norms.

275 pecies, individuals generally maintain tight fidelity to specific foraging sites after extended (up t

276 o be printed into structures with high shape fidelity to the intended computer-aided design.

277 ndard arm over the course of the study, high fidelity to the trial protocol by study staff, and the p

278 ational and binding states while maintaining fidelity to thermodynamic principles and a user-supplied

279 average of 30% less training time to achieve fidelity to treatment than PST therapists and had one-th

280 desired CRISPR-Cas9 traits besides enhanced fidelity, to expand the utility of the CRISPR toolkit.

281 our optimization framework is to ensure high-fidelity tracking of a nominal representation in this la

282 age sequences can be reconstructed with high fidelity using only the facial video and PCA.

283 ed through established metrics of acuity and fidelity, using side-by-side comparison of microarray gr

284 The high-fidelity variants improve discrimination by slowing the

285 impaired by more than 100- fold for the high-fidelity variants.

286 s driving cycles, was evaluated using a high-fidelity vehicle dynamic simulation software (Autonomie)

287 or the maintenance of chromosome segregation fidelity via a specialized chromatin marked by CENP-A wr

288 tution in FMDV polymerase resulted in a high-fidelity virus variant, rF257C, with growth kinetics ind

289 Fidelity was 86%.

290 Spike fidelity was affected by both presynaptic and postsynapt

291 tial templating nucleotide was a pyrimidine, fidelity was decreased.

292 Intervention fidelity was limited by a low prevalence of higher mobil

293 Implementation fidelity was low.

294 Reconstruction fidelity was significantly higher when images from the t

295 in the first coding position, DNA synthesis fidelity was similar to that observed with a 1-nt gap.

296 ptability, appropriateness, feasibility, and fidelity) were additionally evaluated as secondary outco

297 ations to modes that do not limit signalling fidelity, whereas much weaker correlated noise modes inh

298 hown that tTreg cells exhibit strong lineage fidelity, whereas pTreg cells can revert into convention

299 on predicted THg concentration with moderate fidelity, while suspended sediment and water yields pred

300 The difficulty in combining high fidelity with fast operation times and robustness agains