ライフサイエンスコーパス: fimbriae

1 t epithelium via thin fibers called pili (or fimbriae).

2 s required for expression of plasmid-encoded fimbriae.

3 e by specifically increasing production of P fimbriae.

4 major structural subunit of plasmid-encoded fimbriae.

5 sly assessed biomechanical properties of the fimbriae.

6 owever, SL1344DeltafimI was able to assemble fimbriae.

7 r their ability to produce surface-assembled fimbriae.

8 were used to investigate the role of type 1 fimbriae.

9 nce-associated surface fibers termed pili or fimbriae.

10 le bacteria expressing S. Typhimurium type 1 fimbriae.

11 between cellular receptors and Gram-positive fimbriae.

12 antly reduced surface assembly of the type 1 fimbriae.

13 serve as fimbrial receptors, involves type 1 fimbriae.

14 hat assembles adhesive fibres termed pili or fimbriae.

15 mponents of a machinery allowing assembly of fimbriae.

16 5% of all UTI-causing E. coli express type 1 fimbriae.

17 uman extracellular matrices using the type 3 fimbriae.

18 (minor) fimbriae and the 41-kDa fimA (major) fimbriae.

19 was achieved with the antibody against CFA/I fimbriae.

20 FimH adhesins capping the distal end of its fimbriae.

21 , from colonization factor antigen I (CFA/I) fimbriae.

22 ve and virulence properties to P. gingivalis fimbriae.

23 e production of at least 10 of its predicted fimbriae.

24 ls following stimulation with major or minor fimbriae.

25 nisation in atypical/FGL-chaperone assembled fimbriae.

26 opulation-level control of the expression of fimbriae.

27 ooth model, is mediated by long peritrichous fimbriae.

28 only one of these adhesins, known as type 1 fimbriae.

29 uous 54-kb flagellar regulon and 17 types of fimbriae.

30 utational model to simulate the evolution of fimbriae.

31 ent on the expression of the major and minor fimbriae.

32 d S Typhi strains with a deletion in the stg fimbriae.

33 lence factors in particular: urease and MR/P fimbriae.

34 ess stable, non-oxidized DraE forms into the fimbriae.

35 at enables the rapid deployment of bacterial fimbriae.

36 olymerization mechanism of the P. gingivalis fimbriae.

37 lithiasis, and mannose-resistantProteus-like fimbriae.

38 e 1 activation irrespective of P. gingivalis fimbriae.

39 ibuted to this biomechanical feature of ETEC fimbriae.

40 and mode of binding by the poly-adhesive F4 fimbriae.

41 iring adherence factors such as flagella and fimbriae.

42 n the GI tract, promoted expression of these fimbriae.

43 Long polar fimbriae 1 (Lpf1) of Escherichia coli O157:H7 is a tight

44 toxin (PT), filamentous hemagglutinin (FHA), fimbriae 2 + 3 (FIMs), diphtheria, tetanus, Hib, MCC and

45 Type 1 fimbriae, a major UPEC virulence factor, are essential f

46 However, in the absence of fimbriae, A. actinomycetemcomitans still retains the pot

47 rminants, including the attachment adherence fimbriae (AAF) that are necessary for adherence to human

48 factors, including the aggregative adherence fimbriae (AAF), dispersin, the dispersin translocator Aa

49 tissue is mediated by aggregative adherence fimbriae (AAF); however, the receptors involved in EAEC

50 ed the presence of the aggregative adherence fimbriae (AAFs) by a multiplex PCR, targeting the four k

51 Expression of aggregative adherence fimbriae (AAFs), the principal adhesins of EAEC, was req

52 e significantly longer on average, with many fimbriae able to stretch to >20 microm in length.

53 Therefore, P. gingivalis fimbriae activate two distinct TLR2 pathways mediating p

54 of the reported protein agonists, PG1828 and fimbriae, activate TLR2 as strongly as the wild type.

55 ight compound that inhibits FimH, the type 1 fimbriae adhesin, significantly reduced bacterial coloni

56 h urine and along mucus layers, while type 1 fimbriae allow bacteria to adhere to specific receptors

57 However, it is unclear whether CFA/I fimbriae alone are protective and whether other regulato

58 on of mfa, encoding the subunit of the short fimbriae, along with higher levels of Mfa protein.

59 Fimbriae (also known as pili) are appendages that extend

60 ances binding affinity and triggers multiple fimbriae anchoring.

61 genes, encoding the major protein subunit of fimbriae and an arginine-specific proteinase, respective

62 C colonization genes encoding type 1 and F1C fimbriae and capsule biosynthesis were transcriptionally

63 ayfiR suppressed the overproduction of curli fimbriae and cellulose and further verified that deletio

64 Curli fimbriae and cellulose production were increased in the

65 of csgD and bcsA, genes necessary for curli fimbriae and cellulose production, respectively, returne

66 sed assembly mechanism for the P. gingivalis fimbriae and demonstrate the feasibility of using extrac

67 Both fimbriae and flagella have been proven important for vir

68 cesses of adhesion and motility, mediated by fimbriae and flagella, respectively, is essential for di

69 Type 1 fimbriae and flagella, two surface organelles critical f

70 The DraD/AfaD subunit caps fimbriae and has been implicated in the entry of Dr-fimb

71 nal colonization factors (CFs) such as CFA/I fimbriae and heat-labile enterotoxin (LT) are important

72 i CFT073 leads to elevated expression of PAP fimbriae and hemolysin by an unknown mechanism.

73 or the guaB gene in the regulation of type 1 fimbriae and in colonisation of the mouse bladder.

74 genes, which leads to the production of CupD fimbriae and increased attachment.

75 uinis, is the major constituent of bacterial fimbriae and is required for adhesion and biofilm format

76 serum and fecal antibody responses to CFA/I fimbriae and LT but that i.d.

77 ns of Escherichia coli on the tips of type 1 fimbriae and mediates adhesion via a catch bond to its l

78 equence of ArcA that repressed expression of fimbriae and of gingipains.

79 creased transcriptional expression of type-1 fimbriae and reduced adherence to and invasion of human

80 nstruct that constitutively expresses type 1 fimbriae and represses motility, we identified six mutan

81 thogenicity of ETEC expressing newer class 5 fimbriae and suggest suitability of the LT|CS17-ETEC cha

82 least two adhesins: the 67-kDa mfa-1 (minor) fimbriae and the 41-kDa fimA (major) fimbriae.

83 infections are associated with production of fimbriae and the formation of a biofilm.

84 ys two proteinaceous surface structures, the fimbriae and the nonfimbrial extracellular matrix bindin

85 Purified Std fimbriae and UEA both bound to a receptor localized in t

86 st, the fimA and srtC2 mutants lacked type 2 fimbriae and were non-adherent in each of these assays.

87 tigen fraction 1 (F1), the pH 6 antigen (Psa fimbriae), and the outer membrane protease Pla, on the b

88 chinery, capsule, lipopolysaccharide, type 1 fimbriae, and iron acquisition systems during UTI.

89 f surface molecules such as polysaccharides, fimbriae, and outer surface proteins.

90 lysaccharide (LPS) and lipid A, lipoprotein, fimbriae, and phosphorylated dihydroceramides of P. ging

91 Type 1 fimbriae are a known virulence factor in a number of pat

92 Summary Fimbriae are adhesive organelles known to enable pathoge

93 The P. gingivalis fimbriae are assembled via a novel mechanism that involv

94 for the first time, demonstrated that these fimbriae are associated with adherence and hemagglutinat

95 ETEC strains expressing F4 fimbriae are associated with neonatal and post-weaning d

96 ral roles in pathogenesis, the P. gingivalis fimbriae are attractive targets for anti-infective thera

97 These fimbriae are categorized into related classes based on s

98 S. Typhimurium type 1 fimbriae are characterized by mannose-sensitive hemagglu

99 esults show atypical/FGL-chaperone assembled fimbriae are composed of highly flexible linear multi-su

100 Dr fimbriae are comprised of two subunits.

101 The three fimbriae are expressed by ETEC, colonize in similar gut

102 Fimbriae are filamentous structures whose shafts are pri

103 The structural components of the fimbriae are FimA (major subunit), FimI, FimH (adhesin),

104 Dr fimbriae are homopolymeric adhesive organelles of uropat

105 , we are able to show that type 1 and type 3 fimbriae are important colonization factors in the murin

106 st that in Salmonella spp., wild-type type 1 fimbriae are important for attachment to and/or persiste

107 he type 6 secretion system (T6SS) and type 1 fimbriae are important virulence factors required for ga

108 Studies have shown that type 1 and type 3 fimbriae are involved in attachment and biofilm formatio

109 This study reveals that major fimbriae are involved in the initial invasion of osteobl

110 strains, but for the most potent UPEC type 1 fimbriae are involved.

111 Fimbriae are protein-based filamentous appendages that p

112 P fimbriae are strongly associated with upper urinary trac

113 chia coli (ETEC) strains expressing K88 (F4) fimbriae are the major cause of diarrhea in young pigs.

114 The best-studied examples of fimbriae are the type 1 and P fimbriae of uropathogenic

115 cterize the protective properties of the Psa fimbriae are warranted.

116 Escherichia coli (UPEC), flagella and type 1 fimbriae, are critical for colonization of the urinary t

117 ese extracellular structures, called pill or fimbriae, are employed in attachment and invasion, biofi

118 yromonas gingivalis, as well as its purified fimbriae, are known to activate TLR2 and induce proinfla

119 Using coli surface antigen 20 (CS20) fimbriae as a model ETEC colonization factor, we show us

120 Recent understanding about the role of fimbriae as virulence factors points to an evolutionary

121 tor responsible for the expression of type I fimbriae as well as flagellar genes, has also been impli

122 The presence of multiple types of fimbriae assembled by the chaperone/usher pathway can be

123 The biophysical properties of CS2 fimbriae assessed in this work classify them into a low-

124 Fimbriae-associated protein (Fap1) from Streptococcus pa

125 als without detectable chlamydial DNA in the fimbriae at weeks 5 and 12.

126 In Escherichia coli type 1 and Pap fimbriae, at least two adaptors are expressed in additio

127 olled by the major subunit (FaeG) of the K88 fimbriae, because the genes coding for the only other fi

128 along a mannosylated surface under flow, the fimbriae bend and buckle as they interact with the surfa

129 In strains lacking both EmaA and fimbriae, biofilm mass was reduced by 80%.

130 reatment interferes with the function of Mfa fimbriae by reducing P. gingivalis adhesion to Streptoco

131 r ability to uncoil under exposure to force, fimbriae can reduce fluid shear stress on the adhesin-re

132 4), and bacteria expressing FimCDE-deficient fimbriae cannot exploit CXCR4 in vivo for promoting thei

133 associated lineage-specific genes, including fimbriae, capsule, and nutrition utilization genes, spec

134 to be MrkA, a major protein in the type III fimbriae complex, and showed that these serotype-indepen

135 that the fimB mutant, which produced type 2 fimbriae composed only of FimA, like the wild type co-ag

136 ed assay with E. coli expressing mutant F4ad fimbriae confirmed the elucidated co-complex structure.

137 in the mouse model, demonstrating that these fimbriae contribute to uropathogenesis.

138 th P. gingivalis ATCC 33277 or YPF1, a major fimbriae-deficient mutant of P. gingivalis.

139 ranscripts in response to P. gingivalis in a fimbriae-dependent manner.

140 d process, and, therefore, the role of these fimbriae during binding to epithelial cells has been dif

141 rulence genes encoding aggregative adherence fimbriae, E. coli common pilus, flagellin and EAEC heat-

142 (S. typhimurium) to the production of type I fimbriae encoded by the fimAICDHF operon.

143 -wide association approach identifies the (P-fimbriae-encoding) papGII locus as the key feature disti

144 of fimbriae together with the CFA/I and CS20 fimbriae expressed by ETEC strains.

145 impact on the biophysical characteristics of fimbriae expressed by ETEC.

146 On the other hand, the fimbriae expressed by the mutants are significantly long

147 rt across the inner membrane, fewer FimH and fimbriae expressed on the bacterial surface, and decreas

148 elicit a host-based nutrient release if the fimbriae expression is low.

149 imB gene that controls phase-variable type 1 fimbriae expression via the invertible fimS promoter.

150 s of T6SSs in antibacterial activity, type-1 fimbriae expression, cell adhesion, and invasion and int

151 strains causes altered regulation of type 1 fimbriae expression.

152 Three naturally occurring variants of F4 fimbriae (F4ab, F4ac, and F4ad) exist that differ in the

153 Type 1 fimbriae facilitate adhesion to mucosal cells and promot

154 ) (17 [71%] vs 62 [47%]; P = .03) and prf (P-fimbriae family) (13 [54%] vs 40 [30%]; P = .02) were mo

155 Two types of fimbriae, FimA and Mfa1, of the periodontal pathogen Por

156 e adhesive, tip-associated subunit of type 1 fimbriae (FimH) are positively selected in uropathogenic

157 e gene content, the possession of the type 1 fimbriae FimH30 allele, and the production of the CTX-M-

158 The targeted bacterial antigens were CFA/I fimbriae, flagella, lipopolysaccharides (LPS), and capsu

159 , indicating the specialized function of Mad fimbriae for symbiosis.

160 eria, enterics use cellulose and aggregative fimbriae for their attachment to plant surfaces.

161 s-associated and temperature-regulated (Mat) fimbriae) for E. coli serotypes O157:H7 and O18:K1:H7.

162 Tip-localized adhesive proteins of bacterial fimbriae from diverse pathogens confer protection in ani

163 Colonization factor antigen I (CFA/I) fimbriae from Escherichia coli can inhibit autoimmune di

164 drate binding specificity of plasmid-encoded fimbriae from S. Typhimurium.

165 vestigated the biophysical properties of CS2 fimbriae from the CFA/II group.

166 structural similarities seen between class 5 fimbriae (from bacteria primarily causing gastrointestin

167 by which intestinal antibodies against ETEC fimbriae function to prevent disease.

168 However, E. coli type 1 and Pap fimbriae have been reported to be able to assemble fimbr

169 other systems, including flagella and type 1 fimbriae, have been implicated in Salmonella pathogenesi

170 e caused by strains that express K88 (F4)(+) fimbriae, heat-labile enterotoxin (LT), heat-stable ente

171 This functional effect of longer fimbriae highlights the importance of the nonadhesive fi

172 Several FAs mimic DSFs and control motility, fimbriae, hyphae, and biofilm development as well as vir

173 hat the AggR-regulated aggregative adherence fimbriae I enhance inflammation and enable the outbreak

174 ayers, implicating the aggregative adherence fimbriae II (AAF/II) as necessary for barrier dysfunctio

175 igated the role of the aggregative adherence fimbriae II (AAF/II) in EAEC adherence and pathogenesis

176 sly been attributed to aggregative adherence fimbriae II (AAF/II), which confer aggregative adherence

177 tion of the biomechanical properties of CS20 fimbriae impedes sustained adhesion of ETEC to the intes

178 P-induced IL-1beta secretion by means of its fimbriae in a purinergic P2X7 receptor-dependent manner.

179 t of PI3K and was activated by P. gingivalis fimbriae in a TLR2- and PI3K-dependent way, Akt was show

180 In agreement with the role of type 1 fimbriae in binding to PRPs, aggregation of A. oris with

181 One hypothesis of the role of fimbriae in commensals is that they evoke a small but to

182 erythrocytes coursing over immobilized CFA/I fimbriae in flow chambers exhibited low accumulation lev

183 pe of infection, we investigated the role of fimbriae in implant-associated urinary tract infections

184 However, the role of fimbriae in P. gingivalis-osteoblast interactions remain

185 e encoding the major protein subunit of long fimbriae in P. gingivalis; as a result, S. cristatus int

186 Type I fimbriae in Salmonella enterica serovar Typhimurium are

187 The production of type 1 fimbriae in Salmonella enterica serovar Typhimurium is c

188 ae have been reported to be able to assemble fimbriae in the absence of these proteins.

189 the present study, the involvement of major fimbriae in the initial and long-term interactions betwe

190 ng bacterial mutants demonstrated a role for fimbriae in the modulation of TLR-mediated activation of

191 Expression of Std fimbriae in the rosE mutant resulted in increased attach

192 Expression of MR/P fimbriae increases in a cell-density dependent manner in

193 d -DeltafimF mutants were unable to assemble fimbriae, indicating that these genes are necessary for

194 cherichia coli colonization factor antigen I fimbriae, initiates binding of this enteropathogen to th

195 One class of these fimbriae is assembled using a periplasmic chaperone and

196 ce to host intestinal cells mediated by ETEC fimbriae is believed to be a critical first step in ETEC

197 ause the fim operon encoding adhesive type 1 fimbriae is incomplete.

198 Highlighting the importance of MR/P fimbriae is the cotranscribed regulator, MrpJ, which glo

199 Lpf (stands for long polar fimbriae) is one of the few adhesive factors of enterohe

200 CfaA, CfaB, the major pilin subunit of CFA/I fimbriae, is able to spontaneously refold and polymerize

201 function as the major adhesin of the type 1 fimbriae, it also plays an important role in fimbrial as

202 Three antigenic variants of K88 fimbriae (K88ab, K88ac, and K88ad) have been identified

203 disruption mutant with reduced expression of fimbriae lacking all accessory proteins.

204 We now show that P. gingivalis fimbriae lacking FimCDE fail to interact with the CXC-ch

205 Constitutive expression of type 1 fimbriae leads to repression of motility and chemotaxis

206 Fimbriae, lipopolysaccharide (LPS), and extracellular po

207 The expression of the long polar fimbriae (LPF) of enterohemorrhagic Escherichia coli (EH

208 xpress an adherence factor called long polar fimbriae (LPF) that aids in the binding of these bacteri

209 r enhanced by introduction of the long polar fimbriae (Lpf), which facilitate adherence of S Typhimur

210 curli and two operons that encode long polar fimbriae (Lpf).

211 The amounts of fimbriae, LPS, and EPS were also estimated from stained

212 Increased expression of type-1 fimbriae may enhance bacterial interference without conf

213 Type 1 fimbriae mediate adhesion of uropathogenic Escherichia c

214 he failure of this polysaccharide to support fimbriae-mediated adhesion of Actinomyces naeslundii was

215 ant strain, E. coli 83972::lgtCE, impaired P fimbriae-mediated adhesion to human erythrocytes and kid

216 In contrast, CFA/I fimbriae-mediated protection was abated in EBI3(-/-) mic

217 enic major (DPG-3)-, minor (MFI)-, or double fimbriae (MFB)-deficient mutant P. gingivalis strains.

218 actors, including expression of type I and P fimbriae, modulation of hemolysin expression, and expres

219 is dependent on DC-SIGN, whereas the double fimbriae mutant strain does not bind.

220 Using a P. gingivalis major and minor fimbriae mutant, we confirmed that TLR2 binding in whole

221 lass 5 colonization factor antigen I (CFA/I) fimbriae of enterotoxigenic E. coli was proposed to proc

222 Class 5 fimbriae of enterotoxigenic Escherichia coli (ETEC) comp

223 Type 1 fimbriae of Escherichia coli, which are likewise subject

224 The fimbriae of Porphyromonas gingivalis mediate critical ro

225 FimH is the adhesive subunit of type 1 fimbriae of the Escherichia coli that is composed of a m

226 Fimbriae of the human uropathogen Proteus mirabilis are

227 The major fimbriae of this periodontal pathogen mediate binding to

228 ed examples of fimbriae are the type 1 and P fimbriae of uropathogenic Escherichia coli, the major ca

229 Here we showed that the highly conserved Psa fimbriae of Y. pestis (also called pH 6 antigen) are exp

230 pression of DC-SIGN on MoDCs and minor mfa-1 fimbriae on P. gingivalis and is evidenced by robust upr

231 n inhibits the extracellular assembly of Mfa fimbriae on the bacterial surface.

232 and Mfa4, into fibers and the expression of fimbriae on the cell surface.

233 due to the constitutive expression of type 1 fimbriae on the surfaces of the bacteria and that multip

234 ria assemble hair-like fibers termed pili or fimbriae on their cell surface.

235 Vaccination of female DBA/2 mice with CFA/I fimbriae or dscCfaE, each given with a genetically atten

236 Unlike fimbriae or LT, STa has not often been included as an an

237 Here we studied Salmonella atypical fimbriae (or Saf pili), formed by the conserved chaperon

238 E. coli fimbriae, or colonization factor antigens (CFAs), and en

239 us studies, a search for serotype-specific P fimbriae papA alleles, and a BLASTn confirmation of seve

240 Fimbriae participate in biofilm biogenesis and the EmaA

241 Adherence, often mediated by fimbriae, permits bacteria to attach to host cells and e

242 Adhesive surface structures termed fimbriae (pili) mediate interactions of P. gingivalis wi

243 xpresses a plethora of colonization factors (fimbriae/pili), of which CFA/I and CFA/II, which are ass

244 genes involved in iron acquisition (n = 67), fimbriae/pili/flagella production (n = 117), and metal h

245 Adhesion pili (fimbriae) play a critical role in initiating the events

246 single oral dose of purified, soluble CFA/I fimbriae protected against CIA as effectively as did Sal

247 richia coli colonization factor Ag I (CFA/I) fimbriae protects against collagen-induced arthritis (CI

248 hat native forms of both the major and minor fimbriae proteins bind to and signal through TLR2 for th

249 The major and minor fimbriae proteins produced by the human pathogen Porphyr

250 s vaccine candidates are the usher-chaperone fimbriae Psa and Caf.

251 splaying a surface-located oligosaccharide P fimbriae receptor mimic that bound to P-fimbriated E. co

252 We conclude that synthesis of P fimbriae regulates flagellum synthesis to repress motili

253 s provide a comprehensive analysis of type 1 fimbriae regulation in ST131, and highlight important di

254 Fimbriae share a common mode of biogenesis, orchestrated

255 tor and b) are involved in the biogenesis of fimbriae show intriguing protective properties to resist

256 Thus, CFA/I fimbriae stimulate IL-35 required for the coinduction of

257 the association of FimCDE with P. gingivalis fimbriae suggest that FimE may recruit FimC and FimD int

258 . coli body is surrounded by many long, thin fimbriae terminating in a single FimH receptor that is c

259 were caused by strains less likely to have P fimbriae than other rUTI strains (P=.002).

260 ct models for 2 morphological forms of CFA/I fimbriae that are both observed in vivo: the helical fil

261 antigen (Psa) of Yersinia pestis consists of fimbriae that bind to two receptors: beta1-linked galact

262 Assembly of type 2 fimbriae that directly facilitate coaggregation with ora

263 ve enterobacteria produce surface-associated fimbriae that facilitate attachment and adherence to euc

264 ein polymers on their surface called pili or fimbriae that serve either as attachment devices or as c

265 2 agonists include lipopolysaccharide (LPS), fimbriae, the lipoprotein PG1828, and phosphoceramides.

266 found no role for the aggregative adherence fimbriae, the transcriptional activator AggR, or the sur

267 The binding of purified plasmid-encoded fimbriae to a glycanarray suggested that this adhesin sp

268 Direct binding of the major and minor fimbriae to a human chimeric CD14-Fc protein also establ

269 shed specific binding of the major and minor fimbriae to CD14 with classic saturation kinetics.

270 Binding of purified Std fimbriae to Fucalpha1-2Galbeta1-4GlcNAc in a solid phase

271 its the costly expression of plasmid-encoded fimbriae to host environments in a mouse model.

272 e adhesive surface structures termed pili or fimbriae to initiate and sustain infection of host tissu

273 The binding of plasmid-encoded fimbriae to Le(x)-coated wells could be inhibited by co-

274 not observe binding with the major or minor fimbriae to the TLR4-Fc chimeric protein, signaling thro

275 is expresses proteinaceous pili (also called fimbriae) to mediate the following two key events in bio

276 n vivo following adherence, using the type 3 fimbriae, to indwelling devices coated with extracellula

277 ify them into a low-force unwinding group of fimbriae together with the CFA/I and CS20 fimbriae expre

278 ved in this regulation of motility by type 1 fimbriae, transposon mutagenesis was performed on a phas

279 Inquiring into their relevance, CFA/I fimbriae-treated IL-27R-deficient (WSX-1(-/-)) mice were

280 eezers force spectroscopy, we found that CS2 fimbriae unwind at a constant force of 10 pN and have a

281 ncoded mannose-resistant Proteus-like (MR/P) fimbriae, urease, iron uptake systems, amino acid and pe

282 cted ExPEC virulence genes, including pap (P fimbriae), vat (vacuolating toxin), kpsM II (group 2 cap

283 only by UPEC, and (3) dependent upon type 1 fimbriae, we analyzed strains representing epidemiologic

284 After verifying biosynthesis of the chimeric fimbriae, we examined their binding specificities in bac

285 Due to the importance of fimbriae, we focused on the two AAF/II fimbrial gene clu

286 Mad fimbriae were detected on TT01 phase ON cells but not on

287 Fimbriae were downregulated in swarming cells, while gen

288 Ygi fimbriae were necessary for wild-type levels of adherenc

289 Yad fimbriae were necessary for wild-type levels of adherenc

290 The Mad fimbriae were not required for insect pathogenesis, indi

291 Plasmid-encoded fimbriae were purified from the surface of E. coli, and

292 flagellar motility and expression of type 1 fimbriae were unimportant.

293 When whole fimbriae were used, the antifimbrial immune serum that c

294 control E. coli strain, which lack of type 1 fimbriae, were ineffective.

295 acking EmaA structures, but still expressing fimbriae, were observed to have reduced biofilm potentia

296 bits extracellular polymerization of the Fim fimbriae, which are also expressed by P. gingivalis Thes

297 This is accomplished through its surface fimbriae, which induce CXCR4/TLR2 co-association in lipi

298 , the shaft fimbrillin of Actinomyces type 2 fimbriae, which uniquely mediates the receptor-dependent

299 eversible and abolished by pre-incubation of fimbriae with anti-CfaE antibody.

300 Interaction of Mfa fimbriae with S. gordonii is necessary to initiate signa