ライフサイエンスコーパス: final stage

1 ld-Hartwig reaction has been employed in the final stage.

2 ed transformations have been employed at the final stage.

3 intrapeptide hydrogen bonds only form at the final stage.

4 In the final stage 3, we genotyped the 9 most promising SNPs fr

5 ranular dystrophy, 12 had keratoconus in its final stages, 3 had post-herpetic leukoma, and 5 had cor

6 levels of GHR mRNA were only elevated in the final stage (7).

7 At this final stage, 74% (HUES1 cells) and up to 95-97% (HUES7 a

8 bearing the labile depsipeptide ester and a final stage Asn(1) side chain introduction provides futu

9 bearing the labile depsipeptide ester and a final stage Asn(1) side-chain introduction provides futu

10 ower stage at presentation (P = 0.02), lower final stage at last follow-up (P = 0.05), and longer tim

11 The tumour can then progress to the final stage by either seeding a metastasis or acquiring

12 A engages ssDNA in initial, intermediate and final stages conflicts with our data revealing that RPA

13 The final stage consists of both regions slowly evolving to

14 rogressive, debilitating disease that in its final stages cripples the patient.

15 This hypothesis requires that there be a final-stage de-amidination of the corresponding guanidin

16 At the final stage, final particle assembly occurs, possibly th

17 radic and rob(15;21)c-associated iAMP21, the final stages frequently involve duplications of the enti

18 The suppression of the final-stage grain growth is achieved by exploiting the d

19 icel growth is exponential, while during the final stage growth becomes linear and depends on flower

20 amatically and reaching a maximum during the final stages (i.e., sporulation and secondary metabolism

21 Their formation is shown to represent the final stage in a membrane invagination and growth proces

22 biofilms were submerged - recapitulating the final stage in a natural biofilm life cycle.

23 The final stage in cell division, when the cells physically

24 The final stage in exocrine secretion involves translocation

25 the thalamus and the olfactory bulb are the final stage in sensory processing before reaching target

26 -loop-helix protein whose actions during the final stage in stomatal development regulate both cell d

27 Landfills are the final stage in the life cycle of many products containin

28 vel method for lung colonization in vitro, a final stage in tumor metastasis.

29 ion underlying decision formation; and (3) a final stage in which performance ceased to improve with

30 echanisms that control WPB exocytosis in the final stages (including the docking, priming and fusion

31 The final stage involves completion and reorganization of th

32 rom the time of mixing of reactants to their final stage is a heterogeneous process involving a varie

33 u monitoring experiments, in addition to the final stage N1'-acylation of the communesin core, provid

34 At the final stage of acinar cell development, the absence of N

35 ls the expression of genes that complete the final stage of acinar differentiation.

36 had penetrated the cell wall, capturing the final stage of adsorption.

37 reasing interest in the profoundly important final stage of apoptosis - the engulfment process - toge

38 conserved catalytic activity involved in the final stage of bacterial cell wall (peptidoglycan) biosy

39 The intramolecular steps are relevant to the final stage of biological H-cluster maturation.

40 ovide a tool for quantitative ranking in the final stage of CAED may help in progressing toward the d

41 tation of metastasis in a vital organ is the final stage of cancer progression and the main culprit o

42 tation of metastasis in a vital organ is the final stage of cancer progression and the main culprit o

43 on of caspase-3, an enzyme that mediates the final stage of cell death by apoptosis, as well as the T

44 In this final stage of cell death, neurons demonstrated nuclear

45 Cytokinetic abscission, the final stage of cell division where the two daughter cell

46 Cytokinesis, the final stage of cell division, bisects the cytoplasm into

47 Abscission, the final stage of cell division, requires well-orchestrated

48 the peptidoglycan precursor and prevents the final stage of cell wall biosynthesis to enable the loca

49 nce microscopy has been applied to image the final stage of constitutive exocytosis, which is the fus

50 opose a conceptual model that focuses on the final stage of continental extension and break-up, and t

51 The final stage of cytokinesis is abscission, the cutting of

52 RGS-RhoGEF, is required for abscission, the final stage of cytokinesis, in which the intercellular m

53 T Medial olivocochlear (MOC) neurons are the final stage of descending control of the mammalian audit

54 ferent neurons in the brainstem comprise the final stage of descending control of the mammalian perip

55 h minimal lineage specificity, except in the final stage of development when neuron subtype-specific

56 A final stage of development, termed maturation, yields DC

57 To gain insight on the final stage of diabetogenesis, we have studied progressi

58 formation in which core enzyme mediates the final stage of DNA melting near the transcription start

59 s a promoter of matrix mineralization in the final stage of enamel development, and is strongly expre

60 We propose that membrane topology at the final stage of engulfment and FisB-cardiolipin interacti

61 e Escherichia coli enzymes necessary for the final stage of enterobactin synthesis, are released by o

62 rocess becomes irreversible only at the very final stage of evaporation, when the refractive index of

63 ngs identify a new reagent for analyzing the final stage of exocytosis and point to the likely action

64 e Lgl homologue Sro7, proteins acting at the final stage of exocytosis.

65 ough reorganizing local actin network in the final stage of exocytosis.

66 At the final stage of exocytotis, a fusion pore opens between t

67 Goutallier stage 0-III) and increases in the final stage of fatty infiltration (Goutallier stage IV).

68 mtosecond optical transfection system to the final stage of fluorescence imaging to assay for success

69 Translation is the final stage of gene expression where messenger RNA is us

70 roblast growth factors (FGF) 20 and 2 at the final stage of in vitro differentiation enhanced the sur

71 is understood about toxin action during the final stage of infection.

72 mechanisms underlying the protection in the final stage of late PC (48 to 72 hours after PC) are unk

73 hat (1) the cardioprotection observed in the final stage of late PC (72 hour) is mediated by nNOS, no

74 Leaf senescence, the final stage of leaf development, is regulated tightly by

75 ignificant component of alveolarization, the final stage of lung development, occurs postnatally.

76 The final stage of map-based gene isolation is complementati

77 the virus, attaches to the capsid during the final stage of maturation.

78 Platelet (PLT) production represents the final stage of megakaryocyte (MK) development.

79 pore, an essential structure required in the final stage of membrane fusion.

80 ropose that, contrary to current models, the final stage of membrane integration is a regulated proce

81 hat requires cell division, specifically the final stage of mitosis termed abscission.

82 ng and midbody required for cytokinesis, the final stage of mitosis, have not previously been implica

83 ays a critical role in the regulation of the final stage of muscle differentiation.

84 rve both as the mechanical apparatus and the final stage of neural processing through which motor beh

85 centrally within the bone marrow during the final stage of NK cell maturation and hinged on the inst

86 r of experimental restraints (such as in the final stage of NMR structure determination), whether imp

87 N-SLPI is relatively slow and represents the final stage of oxidative folding.

88 The clinico-pathological comparisons for the final stage of Parkinson's disease do support a staging

89 PBP1A and PBP1B, play critical roles in the final stage of peptidoglycan (PG) biosynthesis.

90 , Cyrillic2 is particularly important at the final stage of plant development and, unlike capital A,

91 ion increased development to blastocyst, the final stage of preimplantation development, and promoted

92 ts for CR disease, the poorly responsive and final stage of prostate cancer.

93 bats broaden their echolocation beam in the final stage of pursuit, presumably as a countermeasure t

94 function as a duo in proton transfer at the final stage of reaction, characteristic of the tRNase Z

95 Ligases conduct the final stage of repair of DNA damage by sealing a single-

96 pluripotent stem cell generation during the final stage of reprogramming.

97 We show that the final stage of reticulocyte maturation occurs by a previ

98 nt duct formation occurred normally, but the final stage of secretory coil formation failed.

99 dry seed and opening of the cotyledons, the final stage of seedling establishment.

100 for SA in the cell death that occurs at the final stage of senescence.

101 unseled that the Fontan is typically not the final stage of single-ventricle palliation.

102 phosphatase 1 (PP1, Glc7p) functions in the final stage of SNARE-mediated vesicle transport between

103 The final stage of spermatid terminal differentiation involv

104 fazzin deficiency in Drosophila disrupts the final stage of spermatogenesis, spermatid individualizat

105 istence of a preferred directionality in the final stage of substrate delivery, which begins at the c

106 Cytokinesis, the final stage of the cell division cycle, requires the pro

107 In the final stage of the complex reaction cascade, the so-call

108 nt a nonrandom subset of taxa present in the final stage of the Cretaceous.

109 At the time of the final stage of the decline in viability of each culture,

110 eficiency is more than rickets, which is the final stage of the deficient state among growing childre

111 sparaginyl endopeptidases are crucial in the final stage of the head-to-tail cyclization reaction, bu

112 of patients and is thought to represent the final stage of the multi-stage progression of human canc

113 At the final stage of the nanowire vaporization, the material l

114 (E(m) approximately +0.1 V at pH 6.0); this final stage of the O(2)-tolerance mechanism regenerates

115 The final stage of the process entailed diversification of e

116 The wires were generated at the final stage of the synthesis, which involved the formati

117 ctive manner by Sharpless epoxidation at the final stage of the synthesis.

118 e desired acid in a haloform reaction at the final stage of the synthesis.

119 on is also observed, giving insight into the final stage of the translocation process in atomistic de

120 tive intravascular proplatelet shedding, the final stage of thrombopoiesis.

121 ns about the subcellular localization of the final stage of TPP biosynthesis and the chemical nature

122 nt emitted by the embryo sac that guides the final stage of tube growth.

123 sylated heptapeptide intermediate during the final stage of vancomycin biosynthesis.

124 igenetic switch appeared to occur during the final stage of virion formation.IMPORTANCE For a virus t

125 tolerance at the level of IT neurons, as the final stage of visual object recognition.

126 required for transport, and which marks the final stage of VLP assembly).

127 We find that the final stage of wave growth in shallow estuaries can be p

128 Modulation of the final stages of adipogenesis may provide a novel approac

129 ent with charge-carrier emissions during the final stages of analyte desolvation, with lower charge-c

130 viruses go through a maturation step in the final stages of assembly before being transmitted to ano

131 homeobox gene plays an important role in the final stages of asymmetry.

132 ccharides, the genes encoding enzymes of the final stages of AX synthesis have not been identified.

133 -binding proteins (PBPs) are involved in the final stages of bacterial cell wall assembly.

134 ding proteins (PBPs) are responsible for the final stages of bacterial cell wall assembly.

135 ric DNA translocase that participates in the final stages of bacterial chromosome segregation.

136 sglutaminase with a well defined role in the final stages of blood coagulation.

137 To identify genes misregulated in the final stages of breast carcinogenesis, we performed diff

138 during abscission with earlier events in the final stages of cell division.

139 specific VPS4 activities required during the final stages of cell division.

140 (PBPs) are bacterial enzymes involved in the final stages of cell wall biosynthesis and are the letha

141 are human syndromes caused by defects in the final stages of cholesterol biosynthesis.

142 2) promotes ubiquitylation of CMG during the final stages of chromosome replication in Saccharomyces

143 , highlighting the complex regulation of the final stages of chromosome replication, about which much

144 division septum is required to complete the final stages of chromosome unlinking and segregation.

145 Oritavancin is in the final stages of clinical development for treatment of ac

146 GerE orchestrates the final stages of coat deposition and maturation that lead

147 technology may find broad application in the final stages of completing the Human Genome Sequencing P

148 erve as a practical yet accurate tool in the final stages of computer-aided enzyme design (CAED).

149 In the final stages of cytokinesis, active Rap1 is only present

150 membrane trafficking events required for the final stages of cytokinesis.

151 phosphatidylinositol derivatives during the final stages of cytokinesis.

152 These data reveal a role of hRio1 in the final stages of cytoplasmic pre-40S maturation.

153 assembly, the SMN complex persists until the final stages of cytoplasmic snRNP maturation and may pro

154 ccretion to sustained periods of RSLR in the final stages of deglaciation.

155 s the evolution of protein conformers in the final stages of dehydration of the ESI process and withi

156 as a compact conformer is favored during the final stages of dehydration.

157 The final stages of dengue virus fusion are thought to occur

158 stratum disjunctum, i.e., skin layers in the final stages of desquamation.

159 elopment of the mammary gland is unique: the final stages of development occur postnatally at puberty

160 atio (SSC/TA) increases significantly in the final stages of development.

161 n the first year of disease onset and in the final stages of disease was graded retrospectively.

162 Within the final stages of disease, abnormalities in the oxidation

163 ed only in rapidly progressing events in the final stages of disease.

164 In the final stages of DNA packaging, however, the internal gen

165 estricted to a narrow time window within the final stages of egress.

166 of the spatial and temporal dynamics of the final stages of embolism removal.

167 tory role of IL-5 accessory cytokines on the final stages of eosinophil differentiation.

168 In the final stages of eradication, the virus was entrenched in

169 chondrial and ribosomal clearance during the final stages of erythroid maturation.

170 ltipotential progenitor cell populations and final stages of erythroid maturation.

171 he undecapeptide substance P (SP) during the final stages of ESI.

172 components of the machinery involved in the final stages of exocytosis (the SNAREs) as well as solub

173 The exocyst complex is involved in the final stages of exocytosis, when vesicles are targeted t

174 The final stages of female gamete maturation occur in the vi

175 ion initially correlated with mating and the final stages of female reproductive tract maturation and

176 een scaffold and carrier proteins and in the final stages of FeS protein assembly by transferring clu

177 suggest that MOAS formation may occur at the final stages of fission process and was not associated w

178 re may allow further characterization of the final stages of flavivirus fusion.

179 aneously released into the ER membrane where final stages of folding and assembly are completed.

180 The final stages of folding appear to involve the formation

181 involving Trp140 are formed only during the final stages of folding.

182 rrect packing of the hydrophobic core in the final stages of folding.

183 rbon accumulation at the local scale but the final stages of forest encroachment at the landscape sca

184 the loss of savanna species quickens in the final stages of forest encroachment, and beyond a point,

185 known about the mechanisms that promote the final stages of fork merging in eukaryotes.

186 Two insertion mutants that block the final stages of fruiting body morphogenesis and reduce s

187 pping is a technology that can assist in the final stages of genome assembly by lengthening and order

188 nd intestine--was solely responsible for the final stages of gluconeogenesis and glycogenolysis, in w

189 The myristates are added in the final stages of GPI biosynthesis in a remodeling reactio

190 vely accreting, extremely massive BH, in its final stages of growth.

191 he iron-sulfur cluster domain of HydF in the final stages of H-cluster assembly, i.e. in binding and

192 sins S or L are known to be required for the final stages of Ii removal in different APCs, but the en

193 y questions should be addressed prior to the final stages of implementation.

194 ncoded sporulation (required only during the final stages of infection).

195 ociation from RNA, which is required for the final stages of intron folding.

196 ransient complex with SOD1 and catalyses the final stages of its maturation.

197 oval of the nucleus (nucleophagy) during the final stages of keratinization.

198 ex is present at the OM and functions in the final stages of LPS assembly.

199 strain the abundance of volatiles during the final stages of lunar differentiation.

200 nstead record localized degassing during the final stages of lunar magma ocean (LMO) or later melt cr

201 Neuralized null animals are defective in the final stages of mammary gland maturation during pregnanc

202 etions are likely critical for promoting the final stages of maturation and oocyte developmental comp

203 In this work it is evaluated that, in the final stages of maturation, differences exist in the pro

204 In the final stages of maturation, differences were searched in

205 Thus, RasGRP4 plays an important role in the final stages of MC development.

206 zation European Region and their role at the final stages of measles elimination efforts in Europe, w

207 gress by being discharged into the PV in the final stages of merozoite development to proteolytically

208 Here we report that during the final stages of migration, transcription factor Neurogen

209 ershot and/or searched for the target in the final stages of migration.

210 ions when entering neritic waters during the final stages of migration.

211 ome equivalent) allows the MEN to couple the final stages of mitosis to spindle position.

212 strates by APC/C(Cdh1) plays any role in the final stages of mitosis.

213 es utilize a RACK1 homologue to regulate the final stages of mitosis.

214 properties of the mature virion and thus the final stages of morphogenesis.

215 intermediates and ATP hydrolysis during the final stages of native state assembly.

216 nd growth factor signaling in regulating the final stages of neural circuit specificity such as axona

217 two different Ca(2+)-dependent steps in the final stages of neurotransmitter release.

218 , yet the initial NLT-priming in LNs and the final stages of NLT functional adaptation reflected tiss

219 educe high frequency DCMD spike rates in the final stages of object approach, and slightly delay glid

220 The final stages of of megakaryocyte (MK) maturation involve

221 year period of meiotic arrest; or during the final stages of oocyte growth and maturation, when meios

222 se, short-term, low-dose exposure during the final stages of oocyte growth is sufficient to elicit de

223 follicle cell transition that occurs in the final stages of oogenesis (stage 13/14).

224 versely affects podosomal arrangement in the final stages of osteoclast polarization.

225 In the final stages of ovarian follicular development, the mous

226 the final processing steps accompanying the final stages of particle assembly by an intermolecular m

227 s, termed late domains, which facilitate the final stages of particle budding from the plasma membran

228 During the final stages of phi X174 morphogenesis, there is an 8.5-

229 e Sun and was transported outward during the final stages of planet formation.

230 This buildup is presumed to reflect the final stages of planning and preparation for movement.

231 However, the final stages of platelet formation are less well underst

232 The final stages of polio eradication are proving more diffi

233 he significance of this diversity during the final stages of postnatal development.

234 th non-(18)F-FDG PET tracers that are in the final stages of preclinical development or in the early

235 is crucial to all aerial hawking bats in the final stages of prey pursuit and speculate that beam bro

236 PY detects aggregation of peroxisomes during final stages of programmed cell death and can be used as

237 hanges in protein dynamics that occur in the final stages of protein folding, we have used neutron sc

238 ous proinsulin is in the Golgi region, as if final stages of protein folding/assembly were occurring

239 hysiological function is associated with the final stages of protein/peptide digestion and absorption

240 his ectopic cell division occurs just as the final stages of Purkinje cell development are being comp

241 The final stages of restriction to the T cell lineage occur

242 role of the RPE on photoreceptors during the final stages of retinal morphogenesis.

243 specific role of assembly factors during the final stages of ribosomal subunit assembly and visualize

244 phila, the role of Diaphanous formins at the final stages of secretion appears to be highly conserved

245 nment of the differentiated state during the final stages of somatic cell differentiation is closely

246 nterprotamine sulfur-sulfur bonds during the final stages of sperm maturation.

247 essed specifically in this tissue during the final stages of spinal neural tube closure in wild type

248 Self-gravity plays a decisive role in the final stages of star formation, where dense cores (size

249 In the final stages of TCR-driven TEM, the MTOC precedes, rathe

250 omavirus (HPV) and genital herpes are in the final stages of testing.

251 intermediates paves the way for defining the final stages of the anaerobic pathway.

252 Long-period variable stars arise in the final stages of the asymptotic giant branch phase of ste

253 The final stages of the black-hole merging process, through

254 covalently associated fibrin monomers in the final stages of the blood coagulation cascade.

255 patches, separated from larger cells at the final stages of the cell cycle.

256 fied period of rapid ring contraction in the final stages of the cell cycle.

257 for clinical use and several hundreds in the final stages of the clinical approval pipeline, there is

258 es is believed to play a crucial role in the final stages of the decay of (vortex) quantum turbulence

259 al resource utilization and costs during the final stages of the disease.

260 and serves an essential function during the final stages of the DNA packaging process.

261 he changing epidemiology of outbreaks in the final stages of the eradication initiative.

262 aling, which may act only in the initial and final stages of the GC reaction.

263 In the final stages of the herpes simplex virus 1 (HSV-1) life

264 At the final stages of the movement, subjects experienced simil

265 unprecedented nitrogen rearrangement in the final stages of the pathway involving a ring-opening/clo

266 e kinetic and thermodynamic scheme for these final stages of the reaction mechanism is presented.

267 rable temperatures, to dissect and study the final stages of the reaction where protein dynamics are

268 In the final stages of the reaction, the fully reduced FMN prov

269 e types of structures that remain during the final stages of the simulations are summarized in a glob

270 matrix at the active zone (CAZ) regulate the final stages of the SV cycle preceding exocytosis and th

271 The final stages of the synthesis featured a Stille coupling

272 We present a model of the final stages of the tubulin cofactor pathway that includ

273 At the final stages of the ventral pathway, including the dorsa

274 recovery, even in children presenting in the final stages of their disease, has led to an improved ou

275 The Pitx2 homeobox gene functions at the final stages of this cascade to direct asymmetric morpho

276 t the importance of MT regulation during the final stages of thrombopoiesis.

277 romes, are discussed in the context of these final stages of TTQ biogenesis.

278 aria vaccine candidate RTS,S has reached the final stages of vaccine trials, demonstrating an efficac

279 protein receptor) proteins, which drive the final stages of vesicle fusion, and K(+) channels, which

280 ables in order to co-ordinate and target the final stages of vesicle secretion.

281 e of events coordinating K(+) uptake and the final stages of vesicle traffic.

282 is B virus nucleocapsid at the beginning and final stages of viral reverse transcription based on cla

283 perones, some of which are important for the final stages of virion assembly and egress.

284 the cellular factor Tsg101 to facilitate the final stages of virus budding.

285 genital mutation (Tyr87Ser) that altered the final stages of VWF biosynthesis.

286 mputed tomography (microCT) to visualize the final stages of xylem refilling in grapevine (Vitis vini

287 re associated with SDM, associations between final staging outcomes and clinicopathologic variables,

288 suggest that both forms of stress alter the final stages, rather than the initial step, of the fusio

289 solateral prefrontal cortex plays a crucial, final-stage role, both in integrating mental state and h

290 The third and final stage separates statistically significant (but not

291 Ideally, the final stages should be able to identify the native state

292 But these final-stage sintering processes are always accompanied b

293 ical-wintering sanderlings occurred at their final staging site in Iceland 5-15 days later than birds

294 +/- 9.6% (P < 0.0001) below baseline at the final stage studied (RNFLT loss > 40%).

295 Critical to the final-stage success was the use of a carefully defined S

296 ells pull apart into two daughter cells, the final stage, termed abscission, requires breakage of the

297 ssing the occurrence of the intermediate and final stages, the measurement of free 5-hydroxymethyl-2-

298 known about the molecular mechanisms of its final stage: the transport of the anthocyanin pigment in

299 es sequential removal of particles down to a final stage where the target particle size can be concen

300 on of the complement system proceeded to its final stages, which was marked by the increased generati