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1 G-1 are separable functions of the RAG-2 PHD finger.
2 imilar for flexion and extension of the same finger.
3 l and tangential forces applied by the index finger.
4 eye, chest, left ring finger, and right ring finger.
5 tic pressing or sliding contact of the index finger.
6 BCVA was counting fingers.
7 A-binding residue in the first of three zinc fingers.
8 hat the transcription factor GLI family zinc finger 1 (GLI1) mediates Sulf2 expression during HCC dev
11 anscription factors, VASCULAR PLANT ONE-ZINC FINGER 1 (OsVOZ1) and OsVOZ2, and promotes their degrada
13 to determine that variants of the TOP domain finger 1 motif destabilizes the channel structure and im
14 e transcription factor GLI1 (GLI family zinc finger 1) plays a key role in the development and progre
15 that combined biallelic Cebpa and Gata2 zinc finger-1 (ZnF1) mutations cooperatively induce bilineage
17 esults suggest an active role for GATA3 zinc finger 2 mutants in ER-alpha positive breast tumors.
18 y retrieval-associated increases in BLA zinc finger 268 (zif268) and activity regulated cytoskeletal-
19 ee distinct targeted mutations of A20's zinc finger 7 (ZF7) ubiquitin-binding motif uniformly develop
20 The Arabidopsis E3 ubiquitin ligases RING-H2 FINGER A3A (RHA3A) and RHA3B mediate the monoubiquitinat
21 that Arabidopsis (Arabidopsis thaliana) RING Finger ABA-Related1 (RFA1) and RFA4 E3 ubiquitin ligases
23 h 2 female macaque monkeys moved their index finger against a resisting motor to track an on-screen t
25 reference pulse oximeters (positioned at the finger and earlobe) was 2.8 beats/min for over 65% of th
28 this study, we investigate the role of Zinc finger and SCAN domain containing 4 (ZSCAN4) in human he
30 erns in monkeys were quite distinct for both fingers and directions, which is similar to what was fou
31 Eyes with presenting VA between counting fingers and hand motion at 1 foot were more likely to un
32 an allosteric pocket at the junction of the fingers and palm subdomains by displacing residue V603 i
33 sual acuity was 20/50 (range, 20/20-counting fingers) and the final median visual acuity was 20/40 (r
34 LF4, KLF6, PLZF (promyelocytic leukemia zinc finger), and KLF15, are induced in TG neurons early duri
36 This interaction restricts movements of the fingers, and RdRPs use a subtle conformational change wi
44 geometry are enriched in genomes where zinc fingers are prevalent and specificity transitions would
45 inding activity of the rapidly evolving zinc finger array of PRDM9 (PR domain zinc finger protein 9).
47 al basis, the commands that hold the arm and finger at a target location depend on the mathematical i
49 rns were distinct for movements of different fingers, but were quite similar for flexion and extensio
50 to electronic signals by interdigitated comb finger capacitors at each wing's end along with a capaci
51 niquely at 48 hpi and genes involved in zinc finger CCCH protein, glycosyltransferase, 1-aminocyclopr
52 RNA-binding protein interactors ZC3H14 (zinc finger CCCH-type containing 14) and THOC1 (THO complex p
53 and donor-labeled DNA, we visualized dynamic fingers closing in single Pol beta-DNA complexes upon ad
54 elated conformational change referred to as "fingers closing." Here, we applied single-molecule FRET
55 gether, while neurons that control different finger combinations may be more spatially separated.
58 PHF23, KDM5A and BPTF, suggests a common PHD finger-dependent mechanism that promotes leukemogenesis
60 Long Chain Family Member 5 (ACSL5) and Zinc Finger DHHC-Type Containing 6 (ZDHHC6), was characterise
62 cription regulators with a well-defined zinc finger DNA-binding domain and there is evidence that the
67 he amino acid residue Phe257, located in the finger domain of FMDV polymerase and conserved across FM
68 ingle point mutations in the human MDM2 RING finger domain prevent the interaction of MDM2 with the E
69 educed by MKRN3 mutations affecting the RING finger domain, and that these mutations compromised the
70 ytic SET domain and an intervening MYND zinc finger domain, as well as an extended C-terminal domain.
71 uitinase activity of MKRN3 required its RING finger domain, in order to repress the promoter activity
72 ubiquitin ligase ubiquitin-like PHD and RING finger domain-containing protein 1 (UHRF1) and its DNA m
73 iquitin-like with plant homeodomain and RING finger domains 1 (Uhrf1) is essential for maintenance of
77 h CRISPR/Cas9-mediated depletion of the zinc finger E-box binding homeobox 1 (ZEB1) in claudin-low tu
80 ing the effect of wrist posture on extrinsic finger EMG activity in able-bodied subjects, these resul
81 Located on chromosome 5A, B1 is a C2H2 zinc finger encoding gene with ethylene-responsive element bi
82 revious studies have suggested that the zinc-finger epithelial-mesenchymal transition transcription f
83 ng of how a single mutation in the KLF1 zinc finger exerts effects on erythroid physiology in CDA typ
84 inger muscles, while the EMG activity of all finger extensor muscles were modulated in a similar way
88 ted the population activity in M1 for single finger flexion and extension, using 7T functional magnet
89 tary coupling between shoulder abduction and finger flexion, most probably as a result of the low res
93 R toward M(2)AChR, suggesting that the three-finger fold is a promising scaffold for developing G pro
95 ysis of the H3K4me3-binding sites of the PHD fingers from PHF23, KDM5A and BPTF, suggests a common PH
97 ruppel-associated box domain-containing zinc finger genes on chromosome 19, both of which are associa
98 one-dimensional decoding of the movement of finger groups and in an offline two-dimensional cursor-c
99 This analysis also revealed roles for zinc-finger homeobox domain and SOX2-interacting genes in OFC
102 re, the spreading test exhibits formation of fingers in the moving interfaces, there appear swirls in
103 uble mutation, which disrupts both CCHC zinc fingers in the NC domain, does not abrogate Alix-mediate
104 e to a lack of understanding of how adjacent fingers influence each other's binding specificity.
105 ata included history of cricket-related hand/finger injury leading to > 4 weeks of reduced exercise,
106 phenomenon similar to Saffman-Taylor viscous-fingering instabilities, which occur at moving interface
107 ization of CESA6 through its N-terminal zinc finger is critical in defining its functional properties
108 himeric RAG-2 protein in which the mouse PHD finger is replaced by the corresponding domain from the
111 less glove that can reconfigure all types of finger joint movements and external presses simultaneous
112 ading to > 4 weeks of reduced exercise, hand/finger joint pain on most days of the last month, self-r
115 intricate stem cell niche boundary formed by finger-like extensions generates asymmetry in stem cell
117 migration mechanisms-'push-pull' (forming a finger-like protrusion, adhering to an ECM node, and pul
118 on the stability and activity of RLIM (RING finger LIM-domain-interacting protein, encoded by the RN
120 lated receptor residues and insertion of the finger loop of betaarr1 into the M2R seven-transmembrane
121 taarr1 is different from that adopted by the finger loop of visual arrestin when it couples to rhodop
122 idence of a novel surface at the base of the finger loop that dictates non-GPCR interactions specifyi
123 ovel surface on beta-arr1 at the base of the finger loop, at a site that is distinct from the recepto
124 g of another compound (NITD-640) ordered the fingers loop preceding the F motif, close to the RNA tem
125 formed with a betaarr1 mutant, in which the finger-loop, required to interact with the receptor core
126 tions for the same finger (or combination of fingers) may cluster closely together, while neurons tha
129 Nutritional and phytochemical profiling of finger millet genotypes showed its potentiality to becom
133 nsition of several segments of the thumb and fingers modules and an inward motion of the fingers subd
134 IL3 C terminus has two highly conserved zinc finger motifs containing GRXF residues (designated as Zf
136 ic interacts with the N- and C-terminal zinc finger motifs of GATA-1, causing zinc loss and inhibitio
138 in sensor decodes the complex motion of five finger motions in real-time, and the rapid situation lea
139 l selection of three channels to capture all finger motions with an accuracy of about 99% for seven c
140 mmary, the observation and quantification of fingers movement in human Pol beta reported here provide
142 odied subjects during unrestricted wrist and finger movements across the entire range of motion.
143 his gap, we measured the kinematics of right finger movements in 17 male and female human participant
144 sights into the general organization of fine finger movements in M1.SIGNIFICANCE STATEMENT The primar
147 quantify the posture-dependence of extrinsic finger muscle activity using bipolar fine-wire electrode
148 activity changed by up to 70% in individual finger muscles for the same movement, with the highest l
149 -wire electrodes inserted into the extrinsic finger muscles of able-bodied subjects during unrestrict
152 wrist posture were most prominent for index finger muscles, while the EMG activity of all finger ext
154 t assays showed that wild-type, but not zinc-finger mutant ZFP36L1, bound to HIF1A 3'UTR and mediated
156 xpressing the G551D variant obtained by zinc finger nuclease editing of a human complementary DNA sup
158 irst with meganucleases and followed by zinc finger nucleases, transcriptional activator-like effecto
163 in the functions of the C-tail and sigma3.2 finger of the bacterial factor suggest mechanistic conve
164 enes that include homologs of mammalian Zinc finger of the cerebellum and Purkinje cell protein 4 Dro
165 Our data support a critical role for the PHD fingers of NUP98-PHF23, and related NUP98-KDM5A and NUP9
167 ikely through replacing zinc within the zinc fingers of the critical transcription factor GATA-1.
174 o different movement directions for the same finger (or combination of fingers) may cluster closely t
175 determined by (1) measuring (a) ECG and ear, finger, or toe PPG waveforms or (b) two of these PPG wav
176 uperior to other cPTTs including the popular finger PAT as a marker of changes in BP and systolic BP
179 nfirmed that speckle-type pox virus and zinc finger (POZ) protein (SPOP) functions as a substrate ada
180 , R-wave and toe PPG foot (toe PAT), ear and finger PPG feet, ear and toe PPG feet, and finger and to
181 the ECG R-wave and ear PPG foot, R-wave and finger PPG foot [finger pulse arrival time (PAT)], R-wav
185 at the device can detect N-acetylasparate in finger-prick blood samples from patients with TBI, and t
186 le promise for addressing the limitations of finger-prick blood testing toward tracking glucose trend
187 the development and validation of a at-home finger-prick dried blood spot collection kit and an anal
188 thermore, we demonstrated the feasibility of finger-prick sampling for Ab detection against SARS-CoV-
189 test in capillary blood samples collected by finger-prick was noninferior to venous blood collected i
191 e intervention arm were provided with 2 free finger-prick-based HIVST kits at enrollment and could re
192 ioning of small delicate objects (the "thick fingers" problem), and can be applied to mechanically re
193 hat control flexion or extension of the same finger produce distinct outputs, but interact tightly wi
195 effects and identify a cluster of KRAB zinc finger protein (KZFP) genes that modifies VM-IAPs in tra
201 ajor stimulator of puberty, and makorin RING finger protein 3 (MKRN3) as an inhibitory signal that pr
203 duced expression 1 (REX1; also known as zinc finger protein 42), to be selectively down-regulated in
204 forced expression of the testis-specific PHD finger protein 7 (PHF7) disrupts oogenesis, leading to e
206 cal processes and diseases revealed that PHD finger protein 8 (PHF8, KDM7B) was significantly associa
208 F274, a Kruppel-associated box-A-domain zinc finger protein capable of recruiting epigenetic machiner
209 dent kinase 7 (CDK7), Cyclin H, and the RING-finger protein MAT1 form the heterotrimeric CDK-activati
210 ARS2 (arsenite-resistance protein 2), a zinc finger protein that is essential for early mammalian dev
211 awn inhibition in wheat, encodes a C2H2 zinc finger protein with EAR motifs which putatively function
213 Here, we identify a novel role for the zinc-finger protein ZNF281 in participating in the ordered re
214 NA AC099552.4 (p = 1.2 x 10(-7)), and a zinc-finger protein ZNF655 (gene-based p = 5.0 x 10(-6)).
216 ene encoding a putative DNA binding with one finger protein, controls the stem solidness trait in whe
219 signaling and repression of the muscle ring-finger protein-1 (MURF1)-mediated ubiquitylation of pero
220 ches on two large, independent Cys2His2 zinc finger protein-DNA interaction datasets. We demonstrate
222 me activation, implying that other KRAB-zinc finger proteins (KZNFs) recruit KAP1 prior to blastocyst
223 To accomplish this task, we designed zinc finger proteins (ZFPs) targeting within -300 bps of the
225 approach, we identify a new network of zinc-finger proteins that are expressed in one class of pread
226 as genes coding for aminotransferases, zinc finger proteins, and several uncharacterized proteins.
227 duce three epigenome-editing platforms: zinc-finger proteins, transcriptional activator-like effector
229 nd ear PPG foot, R-wave and finger PPG foot [finger pulse arrival time (PAT)], R-wave and toe PPG foo
230 in ligases, members of the RING between RING fingers (RBR)-type RSL1/RFA family, are key regulators o
233 association was found between force and full finger reperfusion time (beta = -0.033 +/- 0.016; 95% CI
234 Finger temperature was associated with full finger reperfusion time (beta = -0.18 +/- 0.041; 95% CI,
237 showed a consistent difference between full finger reperfusion time and clinician capillary refill t
238 ild had 10 measurements, including five full finger reperfusion time and five clinician capillary ref
239 s should focus on the clinical value of full finger reperfusion time as a monitoring device for hemod
241 producibility and validity of the novel full finger reperfusion time measurement using clinicians' vi
243 Intraclass correlation coefficient of full finger reperfusion time within each patient was 0.76 (95
246 o)RORgammat(lo) (promyelocytic leukemia zinc finger, retinoic acid-related orphan receptor gT) iNKT1
248 hile it is known that shared and unique zinc finger sequences in CTCF and CTCFL enable CTCFL to bind
250 fingers modules and an inward motion of the fingers subdomain-especially the O helix-to engage the p
252 The potential of nuclease-deficient zinc fingers, TALEs or CRISPR fusion systems to treat these d
253 -2.3 +/- 0.21 to -2.4 +/- 0.37; P = .39), or finger tapping (from -2.3 +/- 1.20 to -2.7 +/- 1.40; P =
254 ed verb generation, sentence completion, and finger tapping functional MRI tasks were retrospectively
257 port that, whereas executed movements (i.e., finger tapping) evoked neural responses in both the supe
260 Finally, we reveal that the N, C, and zinc finger terminal domains play unique roles in targeting e
263 contains two tandem C-terminal GRF-type zinc fingers that are absent in the other NEIL paralogs.
264 0.016; 95% CI, -0.065 to -0.0016; p = 0.04), finger thickness (beta = -0.20 +/- 0.089; 95% CI, -0.37
265 ncrease in motor torque rapidly returned the finger to its starting position (lever velocity >200 deg
266 and the path of allostery from the RAG-2 PHD finger to RAG-1, here we employed phylogenetic substitut
267 the fingertip of their dominant hand's index finger to rub or tap three textured surfaces (smooth fla
268 tes to the nucleus and interacts with a zinc finger transcription factor (FgZC1), also required for s
269 identified the constitutively expressed zinc finger transcription factor (TF) Zfp281 as a bidirection
276 Here, we have identified the C. elegans zinc finger transcription factor PQM-1 as a regulator of the
277 -specifically spliced and encodes a BTB zinc-finger transcription factor proposed to be a master regu
278 interaction with the sequence-specific zinc-finger transcription factor ZNF143 and activates the exp
282 hin signalling system; a high number of zinc finger transcription factors; and novel factors that pre
283 /SET domain-containing (PRDM) family of zinc finger transcriptional regulators play diverse developme
285 The SUPERMAN (SUP) gene encodes a C2H2 zinc-finger transcriptional repressor that regulates the flor
286 nly two predicted genes, including C2H2 zinc finger transcriptional repressor TraesCS5A02G542800 upre
287 ratio is presented, in which interdigitated finger-type two-dimensional graphene electrodes are intr
290 ontrolled bandgap behaviors and soft robotic fingers which can measure electrocardiogram from humans
292 s controlling opposite movements of the same finger, while producing distinct outputs, may cluster to
293 stent with locomotor power-grasping with the fingers, while that of the thumb is consistent with huma
294 meric CESA5 by replacing its N-terminal zinc finger with its CESA6 counterpart to investigate the con
296 ier ring is structurally divided into a zinc finger (ZF) sub-ring followed by the oligosaccharide/oli
297 erozygous variants affecting the fourth zinc finger (ZF4) of Wilms' tumor 1 (WT1) (p.Ser478Thrfs*17,
298 or Gag mutants carrying deletions in NC zinc fingers (ZFs) or a nonmyristoylated version of Gag.
299 The CPSF30 subunit contains five CCCH zinc fingers (ZFs), with ZF2-ZF3 being required for the recog