ライフサイエンスコーパス: firm

1 driven by an exploratory search for newcomer firms).

2 quent employment in a startup or established firm.

3 uced participation from large pharmaceutical firms.

4 of existing structures in selecting partner firms.

5 list and who became wealthy by founding new firms.

6 obtained through collaboration with private firms.

7 nsive screening processes of venture capital firms.

8 rogradation, water mobility, and bread crumb firming.

9 FIRM ablation terminated AF to sinus rhythm or atrial fl

10 The increase from ETS firms accounts for about 1% increase of the regional low

11 truct a labor flow network of over 4 million firms across the world, from which we reveal hierarchica

12 latter could explain the observed failure in firm adherence and transendothelial migration under flow

13 Both mouse and human eosinophils showed firm adhesion and degraded up to 27 +/- 3.1% of the subs

14 ace may control the balance between cellular firm adhesion and migration.

15 Transition of PMN rolling to firm adhesion critically depends on Coro1A by regulating

16 colonization of the human intestine requires firm adhesion of bacteria to insoluble substrates under

17 Specifically, Slit2 blocked the capture and firm adhesion of human neutrophils to inflamed vascular

18 Together, these changes translate to higher firm adhesion of infected monocytes on endothelium, whic

19 ar adhesion molecule-1 (ICAM-1) mediates the firm adhesion of leukocytes to endothelial cells and ini

20 ICAM-1 is required for firm adhesion of leukocytes to the endothelium.

21 Moreover, HLA I mIgG2a promoted firm adhesion of monocytes to ICAM-1 through Mac-1, whic

22 ents that originate from the ICAM-1-mediated firm adhesion of neutrophils that regulate VE-cadherin's

23 emonstrate that the IL-1R type 1 governs the firm adhesion of neutrophils to the inflamed spinal cord

24 Efficient T cell responses require the firm adhesion of T cells to their targets, e.g., virus-i

25 onse to collagen in platelet-rich plasma and firm adhesion on VWF under arterial flow.

26 hear flow, and prostate cancer cells exhibit firm adhesion to BMEC via beta1, beta4, and alphaVbeta3

27 arization, which is important for neutrophil firm adhesion to endothelia.

28 molecule 1 (ICAM-1) clustering, and monocyte firm adhesion to HLA I Ab-activated endothelium.

29 iated by the membrane-distal D1, followed by firm adhesion to the primary binding site in D2.

30 ly of the immunological synapse and mediates firm adhesion to the target.

31 Upon their activation and firm adhesion to vascular endothelial cells (VECs), leuk

32 t integrin signaling but that LFA-1-mediated firm adhesion under conditions of shear flow requires do

33 hA2 knockdown significantly reduces monocyte firm adhesion under flow.

34 caused increased rolling velocity, decreased firm adhesion, aberrant crawling, and strongly reduced t

35 ues involves elements of neutrophil rolling, firm adhesion, and crawling onto the EC surface before e

36 sclerotic inflammation by promoting monocyte firm adhesion, whereas smooth muscle EphA2 expression ma

37 , Jurkat and primary MS patient-derived PBMC firm adhesion.

38 ' surface, MBDual enhanced the percentage of firm adhesion.

39 q-VWF complexes induced platelet rolling and firm adhesion.

40 However, the lack of firm age estimates for older Pleistocene terminations co

41 ty of the bred cultivars are homozygous for "firm" alleles suggests that this locus is a signature of

42 d the "soft" alleles were dominant over the "firm" alleles.

43 FIRM analysis revealed sources in the right atrium in 85

44 Few firm and discrete lymph nodes were palpable in the right

45 tcome measure was time to balance failure on firm and foam surface testing.

46 The gels produced with LBA were less firm and released less volatile aroma compounds than the

47 Multivalency is nature's way to establish firm and specific interactions when the binding sites of

48 oreign PhDs who first work in an established firm and subsequently receive a green card are more like

49 The margin of the subretinal abscess became firm and the central area resolved after the operation.

50 tributions are similar to those observed for firms and are consistent with a Bose-Einstein preferenti

51 sponsorship between startups and established firms and not by foreign PhDs' preferences for establish

52 , carbon markets reshape incentives faced by firms and reduce the value of emissions.

53 ical model simulating the whole ecosystem of firms and showed that the system is already in an unstab

54 with CMX + CAF sites tending to be "equally firm" and CTG + CAF sites "more firm." Patient satisfact

55 source (focal impulse and rotor modulation [FIRM]) and then conventional ablation in 27 patients (FI

56 the ablation results in latest studies using FIRM are discussed.

57 nopoly state in which growth of middle sized firms are suppressed.

58 When financial firms are undercapitalized, they are vulnerable to exter

59 mc-deficient B cells have normal rolling and firm arrest on high endothelium venules (HEV), thereby a

60 zing slow cell rolling and the transition to firm arrest.

61 The WHO engaged a bank and an accounting firm as DDM partners to support disbursement of and acco

62 tolerance, although encouraging, are not as firm as they could have been if we had used randomizatio

63 nformation with all four domains packed in a firm assembly, whereas at acidic pH, the three IgG-bindi

64 We establish a firm association between IDH mutations and serum 2HG con

65 ps, along with other employees of innovative firms, at 4 locations of a prominent innovation and cowo

66 thermore, the GSL concentration required for firm attachment is significantly larger for H type 1 tha

67 rization signaling axis regulates neutrophil firm attachment to endothelium.

68 entration needed for (i) noroVLPs to achieve firm attachment to the bilayer prior to competition and

69 partial IVC ligation revealed that leukocyte firm attachment was increased in WT mice compared to mic

70 Firm attachments between kinetochores and dynamic spindl

71 e Learning for Antiviral Peptide Prediction (FIRM-AVP) approach achieves a higher accuracy than eithe

72 -catalyzed HAT alkene coupling, and create a firm basis for elucidation of mechanisms in the growing

73 transmembrane proteome of CyHV-3 provides a firm basis for further research on alloherpesvirus VTPs.

74 riants identified in familial DCM provides a firm basis for offering genetic investigations in affect

75 se to injury and infection and established a firm basis for our understanding of inflammation and tis

76 r as a true sea ice obligate and providing a firm basis for projection under scenarios of future clim

77 ion of these two biomarkers should provide a firm basis for risk stratification, both in clinical pra

78 Our findings create a firm basis for the development of EVs as smart drug carr

79 It also provides a firm basis for the further research on alloherpesvirus v

80 Combined, this evidence provides a firm basis for understanding the age-dependent incidence

81 nd medical groups acquired by private equity firms between 2013 and 2016.

82 conventional ablation alone in 65 patients (FIRM blinded).

83 ble (85.2% of FIRM-guided patients, 23.1% of FIRM-blinded patients).

84 rtile range: 224 to 1,563 days), compared to FIRM-blinded therapy, patients receiving FIRM-guided abl

85 ld, suggesting that it may contribute to the firm bonds between kinetochores and the flared plus ends

86 pilots increase low-carbon innovation of ETS firms by 5-10% without crowding out their other technolo

87 ispatchable source with zero contribution to firm capacity.

88 ot associated with permit price, auction, or firm characteristics, but is driven by mass-based allowa

89 12-h fast, subjects ingested 33 g fat from a firm cheese (young cheddar), a soft cream cheese (cream

90 mpared the impact of dairy fat provided from firm cheese, soft cream cheese, and butter on the postpr

91 ss the "precolonization" theory, accord it a firm chronological framework, and demonstrate that the q

92 port of any of these models is limited and a firm conclusion is missing.

93 are heterogeneous and lacked power to draw a firm conclusion.

94 and withdrawal, limiting the ability to draw firm conclusions (particularly about safety).

95 The evidence was too limited to make firm conclusions about differences in the benefits and h

96 of other promising interventions, precluding firm conclusions as to their effectiveness.

97 However, no firm conclusions can be drawn in respect to the most eff

98 )], have been much less investigated, and no firm conclusions can be drawn.

99 7-14, but further follow-up is needed before firm conclusions can be reached on the efficacy and cost

100 vestigation in additional populations before firm conclusions can be reached.

101 underpowered and retrospective in nature, so firm conclusions cannot be made.

102 This uncertainty precluded firm conclusions for 53% of species and IBAs because 95%

103 oblems have limited researchers from drawing firm conclusions from the data.

104 est productivity to NAO have so far hampered firm conclusions on its impacts.

105 sample size and case-control design preclude firm conclusions on KS risk or pathogenesis.

106 but there is insufficient evidence to reach firm conclusions on the clinical or cost-effectiveness o

107 It is not possible, however, to draw any firm conclusions on the potential biological significanc

108 radictory data renders it impossible to draw firm conclusions on the role of TFAs in modifying fetal

109 This fact prohibited firm conclusions regarding the contribution of stable Ig

110 ons of the available studies, we cannot draw firm conclusions to inform a population level approach t

111 ty of evidence is still insufficient to draw firm conclusions, not supporting neither discouraging th

112 Although wide CIs preclude firm conclusions, the intervention may have increased ED

113 nd patient groups makes it difficult to draw firm conclusions.

114 antity and consistency among studies to draw firm conclusions.

115 ide by cop"), data are too uncertain to draw firm conclusions.

116 Although there is firm consensus that anthropogenic activities have transf

117 This places firm constraints on the total crustal residence time of

118 In addition, we report firm correlations between Tier 2 autologous neutralizati

119 ented with a 5 mm x 7 mm x 3 mm pedunculated firm cystic lesion on the inferior palpebral conjunctiva

120 d to various degrees, although in some cases firm data are lacking with regard to certain types of in

121 easing availability of high quality business firms' data.

122 ation would be aided by setting a reasonably firm date for OPV withdrawal as far in advance as possib

123 d induce local pathogenic changes, but lacks firm demonstration.

124 ce in the exoplanet population has escaped a firm detection.

125 uisitions occurred in 40 states with most PE firms developing multistate platform companies.

126 individuals aged >50 years: 1) cases with a firm diagnosis of mild cognitive impairment or dementia

127 Fourth, one now has firm, disproof-based chemical-mechanism precedent for tw

128 s, maltose showed no functionality on pellet firming during storage.

129 Setting biological control on a firm economic foundation would help to broaden its utili

130 -induced remnant magnetization spectroscopy (FIRMS) enable the binding behavior of drug molecules wit

131 powered for a 25% relative reduction showed firm evidence (cumulative z-curve crossed the monitoring

132 adaches have been proposed, but establishing firm evidence for any of them has proved elusive.

133 However, there was no firm evidence for associations between microbiota and me

134 In summary, the present data provide firm evidence for at most, three Gsp-1 genes in wheat, a

135 Together, our data provide firm evidence for involvement of NOTCH signalling in HLH

136 ve crossed the futility boundary, indicating firm evidence for lack of a 10% or greater reduction in

137 decrease in repeat revascularization with no firm evidence for reduction in death and myocardial infa

138 However, firm evidence for the existence and functional importanc

139 We also present firm evidence for the existence of very long-term variat

140 X-ray absorption spectroscopy provides firm evidence for the presence of Ni(0) centers, whereas

141 eduction in repeat revascularization with no firm evidence for the reduction in death or myocardial i

142 agement programs have shown promise but lack firm evidence of effectiveness and scalability.

143 To date, there is no firm evidence that meiosis, the hallmark of gametogenesi

144 Overall, the study provides firm evidence that methanol is formed at the interface o

145 No firm evidence was found for the efficacy of all early ph

146 s not explained by a wide range of regional, firm, executive, and cultural variables.

147 tion led to a policy framework that places a firm focus on African leadership and capacity building a

148 istical properties of the growth of business firms follow the same sorts of power laws that character

149 Here we develop this idea and place it on a firm footing by employing a standard decision-theoretic

150 slated into clinical practice by providing a firm foundation for clinical laboratories to set appropr

151 blies both in vivo and in vitro, providing a firm foundation for creating tailored biomimetic nanocom

152 c basis for the biosynthesis of 1 and sets a firm foundation for querying the biosynthetic potential

153 population, we validated the procedure as a firm foundation for standardized somatic-mutation analys

154 y erythropoiesis and anemia, one must have a firm foundation of indices that accurately measure red b

155 tigations of this elusive molecule provide a firm foundation to better understand its potential physi

156 P, CNV, or PAV across the panel, providing a firm foundation to identify functional variation associa

157 erent set of pathogenic processes, providing firm foundations for studies aimed at dissecting disease

158 rated for publicly-traded U.S. manufacturing firms from 1974 to 1993 apply to the same sorts of firms

159 from 1974 to 1993 apply to the same sorts of firms from 1993 to 2015, to firms in other broad sectors

160 babilities towards newcomers and established firms from the data, we find that endogenous mechanisms

161 pes (alleles) associated with either soft or firm fruit were identified for qP-FF4.1 in the sweet che

162 10 of which are likely pathogenic, giving a firm genetic diagnosis for 2.9% of patients.

163 t requires that interpretation be based on a firm genetic, biochemical, and structural foundation.

164 ect: no contact, light grip (< 1 N) (LG) and firm grip (FG).

165 cal role of the Ska complex in maintaining a firm grip on dynamic microtubules.

166 by grip context (no contact, light grip and firm grip), as well as how they are co-ordinated with th

167 When GVS was applied during firm grip, hand and ground reaction forces were generate

168 over the interaction length scale, providing firm ground for the applicability of statistical physics

169 These experiments put forward on firm ground that the chiral-induced spin selectivity eff

170 Here, we show that the scaling properties of firm growth previously demonstrated for publicly-traded

171 Firm guidance is needed for primary care on the use of l

172 d then conventional ablation in 27 patients (FIRM guided) and conventional ablation alone in 65 patie

173 Randomized trials of FIRM-guided ablation and mechanistic studies to determin

174 FIRM-guided ablation is more durable than conventional t

175 to FIRM-blinded therapy, patients receiving FIRM-guided ablation maintained higher freedom from AF a

176 All FIRM-guided ablation procedures (n=24; 50% paroxysmal) a

177 In the Indiana University FIRM registry, FIRM-guided ablation produced high single-procedure succ

178 rted by substantially improved outcomes from FIRM-guided ablation, resulting in increased attention t

179 rs and describe acute procedural outcomes of FIRM-guided ablation.

180 rdiographic monitors when possible (85.2% of FIRM-guided patients, 23.1% of FIRM-blinded patients).

181 hin SUR1's ABC core, allowing it to act as a firm 'handle' for the assembly of metastable mutant SUR1

182 FIRM-identified rotor sites did not exhibit quantitative

183 c mapping showed no rotational activation at FIRM-identified rotor sites in 23 of 24 patients (96%).

184 was administered by an international polling firm in June 2014.

185 A private firm in Rwanda is distributing forced-draft pellet-fed s

186 (0.5 g maltose/100 g flour), did not retard firming in comparison to reference pellets (crumb matrix

187 Recently, growth mechanism of firms in complex business networks became new targets of

188 iveness of several inexpensive features that firms in four industries could implement with existing o

189 er broad sectors (such as materials), and to firms in new sectors (such as Internet services).

190 he same sorts of firms from 1993 to 2015, to firms in other broad sectors (such as materials), and to

191 ding risk, whereas dose reductions without a firm indication may decrease the effectiveness of stroke

192 ed by percutaneous drainage, and although no firm inference can be made from such a small series, we

193 tion of heterogeneous nucleation and provide firm insight to the wetting of nanosized objects.

194 ydrogels incorporating LN-511-E8 resulted in firm integrin-mediated adhesion to the scaffold and well

195 with a reduction in striatal DAT despite its firm involvement in DLB pathology.

196 while a similar increase from large non-ETS firms is also induced by the ETS.

197 The growth of business firms is an example of a system of complex interacting u

198 hat the probability of merger between bigger firms is bigger than that between smaller ones, and such

199 by foreign PhDs' preferences for established firm jobs, risk tolerance, or preference for higher pay.

200 Firm-juicy cultivars containing high VOC concentrations

201 Generally, firm-juicy cultivars had a shorter time to first swallow

202 avening methods (chemical vs. biological) on firming kinetics were not significant, which was confirm

203 pressive disorder (MDD) has not yet provided firm leads to its underlying molecular biology.

204 This study investigated the regulation of firm leukocyte adhesion to human brain endothelium by tw

205 prostheses beyond simple environments (e.g. firm level ground without load) that represent only a su

206 -linearity exists in the correlation; higher firm-level emission abatements can realize larger tradin

207 resolution (10 km x 10 km) using a detailed, firm-level emission inventory.

208 Here we provide firm-level evidence of the innovation effect directly fr

209 Based on the complete firm-level transaction records of the EU ETS Phases I an

210 However, establishing a firm link between macro-scale brain network organisation

211 genetic and functional studies demonstrate a firm link between SIM1 loss of function and severe obesi

212 mediated B cell motility arrest and leads to firm, long-lasting B cell adhesion to the APC.

213 side were higher in green (h degrees higher) firm M1 to M3 stages.

214 dies of fibrillation, and how this motivated FIRM mapping in humans.

215 FIRM mapping revealed a median of 2 (interquartile range

216 on using focal impulse and rotor modulation (FIRM) mapping that rotors act as human atrial fibrillati

217 include focal impulse and rotor modulation (FIRM) mapping, and initial results reported with this te

218 l under standard and tax instruments, and if firms market the abated natural gas, private net benefit

219 inical examination enabled confirmation of a firm mass occupying the retroareolar region and the oute

220 had solitary, deep, 2 cm hard and moderately firm masses, respectively.

221 mpanies the mesenchymal mode of migration on firm matrices and is facilitated by Rac1 activation.

222 Notably, firm matrices do not support microvesicle release, where

223 Lack of this basic information precludes a firm mechanistic understanding of TES effects.

224 In such a case, firms might cut emissions even though market prices are

225 On palpation, few ill-defined firm mobile masses were found in the upper outer quadran

226 of endothelial miR-126 and miR-126* enhanced firm monocyte and T cell adhesion to hCMEC/D3 cells, whe

227 of distress and had bilateral submandibular firm nonpulsatile tender masses, each estimated at 3-4 c

228 Given the absence of firm observational constraints, it remains to be seen wh

229 Groups of firms often achieve a competitive advantage through the

230 nd publicly available press releases from PE firms or platform companies.

231 ectly by Focal Impulse and Rotor Modulation (FIRM) or coincidentally when anatomic ablation passes th

232 Data were mainly accessible for smaller firms, orphan drugs, products in certain therapeutic are

233 Four follow-up surveys tracked outcomes for firms over 2 years and showed that personal initiative t

234 be "equally firm" and CTG + CAF sites "more firm." Patient satisfaction was high, with no statistica

235 Physical examination demonstrated a fixed, firm pelvic mass; a computed tomography-guided biopsy co

236 tudies of reduced flavins/flavoproteins on a firm photophysical footing.

237 time of admission revealed scattered 1-3-cm firm pink hyperpigmented subcutaneous nodules, several o

238 Unexpectedly, free Hb also promoted firm platelet adhesion and stable microthrombi on VWF.

239 eceptor glycoprotein VI and strongly affects firm platelet adhesion on von Willebrand factor (VWF) un

240 enabling high-affinity GPIbalpha binding and firm platelet adhesion to a partially disordered A1 doma

241 glycoprotein ligand 1 axis, followed by (2) firm platelet adhesion to the endothelium via interactio

242 tunities such as these likely exist wherever firms possess environmentally relevant data not accessib

243 lassical novae display nova shells, but lack firm post-eruption ages, and are also dwarf novae at pre

244 Although firm prevalence data are lacking, there is a strong impr

245 On follow-up, freedom from AF after a single FIRM procedure for the entire series was 95% (PAF), 83%

246 h a simulated breakfast cereal manufacturing firm procuring grain, containerboard boxes, plastic pack

247 that personal initiative training increased firm profits by 30%, compared with a statistically insig

248 n differed with storage temperature, and the firming rate was evidently lowest during frozen storage.

249 d stored at -25 degrees C, while the highest firming rate was observed for finished bread from parbak

250 The lowest firming rate was observed for finished bread resulting f

251 nt, which was confirmed by comparable Avrami firming rates k.

252 However, more studies are needed before firm recommendations can be made.

253 Research is needed to inform firm recommendations on how to protect this vulnerable p

254 med in a prospective randomized trial before firm recommendations regarding clinical practice can be

255 In the Indiana University FIRM registry, FIRM-guided ablation produced high single

256 lopment of mechanistic relationships between firming-relevant additives and structural crumb matrix a

257 gion well separated above Europa's limb is a firm result and not invalidated by our 2014 STIS observa

258 programs that reduce harassment should help firms retain current and aspiring women managers.

259 Accumulating evidence has established a firm role for synaptic plasticity in the pathogenesis of

260 s are often attributable to processes in the firm's upstream supply chain.

261 gram, the Iranian cyber attack on the energy firm Saudi Aramco, the persistent cyber espionage carrie

262 oining new terms that are not supported by a firm scientific basis and encourage research into the cr

263 that anchored its dorsal exoskeleton in the firm sediment during the body inversion moult procedure.

264 s in vivo, we show that the NPC lacks such a firm size threshold; instead, it forms a soft barrier to

265 g 2007-2018 pricing data from the investment firm SSR Health for branded products available before Ja

266 lf-employment, small business ownership, and firm startup rates.

267 at the dead body of a young male, selected a firm stem of grass, and started to intently remove debri

268 We provided a firm structural basis for this stabilization with an ato

269 with several large ecchymoses radiating from firm subcutaneous nodules on the buttocks, arms, and thi

270 ed, were probably left earlier on relatively firm substrates that predated the deposition of soft mud

271 o move to a startup than another established firm, suggesting that permanent residency facilitates st

272 magnetic resonance spectroscopy, providing a firm support for the tyrosyl radical in the HCO enzymati

273 spatch diagnosis of cardiac arrest, use of a firm surface for CPR, sequence for starting CPR (compres

274 nditions or eyes-closed balance testing on a firm surface was not more common among participants with

275 n a 3-month-old infant that presented with a firm swelling in the chest wall and was histopathologica

276 ct on the atmosphere and climate, provides a firm target for inventories of the global CH(4) budget,

277 pigments from PSP can be challenging due to firm texture and high polyphenol oxidase (PPO) content.

278 this sample (JPP2) was more reddish and less firm than other samples.

279 n and activation leads to the formation of a firm thrombus and thus the sealing of a damaged blood ve

280 of PGMs) reflecting the rational response of firms to changing prices.

281 technology to lower this barrier by enabling firms to inform customers of products' environmental foo

282 social media site, contracting with Chinese firms to install the same censoring technologies as exis

283 These examples illustrate the potential for firms to lower their overall carbon footprints while imp

284 here also remain continued disincentives for firms to measure and pay the full costs of their supply

285 and II, here we show that the participating firms' trading profits and their emission abatements are

286 te pro-oncogenic function of PKCzeta without firm understanding of detailed molecular mechanism.

287 t their emergence in the human brain lacks a firm understanding.

288 benefit of this method is that it provides a firm upper bound on the average molecular weight of DOM,

289 glutathione-Cu(I) equilibrium system sets a firm upper limit on the thermodynamic availability of in

290 We find evidence that is consistent with firms using acceleration trade-offs to achieve complianc

291 s have expanded into the electricity grid to firm variable renewable generation, increasing the effic

292 nding to the immobilized GAG brushes ensures firm virus attachment to the interface.

293 Waxy paper-like vitreous with firm vitreous adhesions beyond major arcades and along r

294 Cake crumb firming was evaluated by texture analysis.

295 to $15 billion yearly would occur if service firms were to reach median research and development fund

296 procurement organizations to participate in firm-wide environmental impact reduction targets.

297 on-active regions in brain imaging data, and firms with different financial risk in company balance s

298 Two, in firms with more women managers, harassment programs may

299 likely to respond negatively to training, in firms with more women managers, programs work better.

300 Focal impulse and rotor modulation (FIRM) with an endocardial basket catheter was used in al