ライフサイエンスコーパス: first cousin

1 The sisters were born to parents who are first cousins.

2 ii) close age mates, and (iii) maternal half-first cousins.

3 Four siblings and their 2 parents, who are first cousins.

4 n which nearly half of marriages are between first cousins.

5 pairs, second-degree (2 degrees ) relatives, first cousins, and unrelated pairs but is unable to dist

6 The patient's parents, who are first cousins, are asymptomatic and have only minor redu

7 trait value, equivalent to the offspring of first cousins being 1.2 cm shorter and having 10 months'

8 This risk is 16.5-fold higher for first cousins but is significantly more increased for sk

9 e present in the proband and the 32-year-old first cousin, but not in a healthy relative.

10 2.5 years) of Iranian-Azeri ancestry born to first-cousin consanguineous parents presented with clini

11 not find evidence that this is explained by first-cousin consanguinity, despite a reported social pr

12 Her sister and a first cousin died of cirrhosis (ages 19 and 6 years) and

13 ages 19 and 6 years) and another 32-year-old first cousin had a self-limited liver disorder in childh

14 relatives (HRR, 1.32; 95% CI, 1.19-1.47) and first cousins (HRR, 1.15; 95% CI, 1.07-1.25), compared w

15 ow that restricting analysis to offspring of first cousins is an effective way of reducing confoundin

16 iking: F(ROH) equivalent to the offspring of first cousins is associated with a 55% decrease [95% CI

17 ause of CID in 2 siblings, the products of a first-cousin marriage, who experienced recurrent bacteri

18 both this founding effect and the customary first-cousin marriages among the ancestral Islamic popul

19 ncy populations do exist because of frequent first-cousin marriages and/or a higher mutation frequenc

20 ed Jewish families, 12 were the offspring of first-cousin marriages.

21 In the Middle Neolithic we evidence first cousin mating practices and strong genetic continu

22 ue ADCC, in which the affected daughter of a first cousin mating was presumed to be homozygous for th

23 1.1, p=0.11) and infants whose parents were first cousins (odds ratio=2.7 vs. 0.7, p=0.07).

24 tives (FDRs) and second-degree relatives and first cousins of individuals with CRC, and stratified ri

25 FDRs, second-degree relatives, and first cousins of patients who undergo colonoscopy and ar

26 gree relatives, second-degree relatives, and first cousins of probands and controls were identified t

27 Siblings and first cousins of probands with JIA have an increased ris

28 with a recessive disease whose parents were first cousins, on average, 11% of their genomes were hom

29 he last 45,000 years, we detect low rates of first cousin or closer unions across most ancient popula

30 relatives (OR, 1.99; 95% CI, 1.49-2.65); and first cousins (OR, 1.35; 95% CI, 1.03-1.77), providing e

31 te a drop of 0.6 s.d. among the offspring of first cousins (P=0.003-0.02 depending on the model).

32 re also observed for avuncular (r = .22) and first-cousin pairs (r = .28), which supports the hypothe

33 nalysis on genomic DNA from a H-JEB child of first-cousin Pakistani parents, and identified a homozyg

34 alestinian family consisting of asymptomatic first cousin parents and three children affected with ne

35 The proband, the second child of the first cousin parents of Turkish origin, was diagnosed wi

36 Here we use a three-generation, double-first-cousin pedigree design to estimate additive, sex-l

37 a and their first-degree, second-degree, and first-cousin relatives were located through linkage to t

38 We describe first cousin sibling pairs with focal epilepsy, one of e

39 , 2.70; 95% CI, 2.30-3.14, respectively) and first-cousin (SMR, 1.85; 95% CI, 1.70-2.00 and SMR, 1.50

40 marriage practices from modern Soqotri, with first-cousin unions occurring significantly less frequen

41 all, 2013 (18%) babies were the offspring of first-cousin unions.

42 27 babies of Pakistani origin had parents in first-cousin unions.

43 the serum of the proband and the 32-year-old first cousin using mass spectrometry.

44 ration (e.g. aunt-niece versus niece-aunt or first cousins versus great aunt-niece).

45 The RR of JIA in first cousins was also increased (5.82, 95% CI 2.5-13.8,

46 , in which the affected daughter of affected first cousins was presumed to be homozygous for the purp

47 eds, e.g., pairs of siblings together with a first cousin, we use a likelihood analysis to find 1-df

48 t that 6% (1/16) of the genome of a child of first cousins will be homozygous and that the average ho

49 Using whole-genome sequencing in two first cousins with TAAD, we identified a missense mutati

50 We describe the case of 2 brothers, sons of first cousins, with lifelong history of abnormal bleedin