ライフサイエンスコーパス: first-order rate constant

1 rder rate constants (k) from observed pseudo-first-order rate constants.

2 2 after a UV(222) dose of 8 mJ/cm(2) (pseudo-first order rate constant = 0.64 cm(2)/mJ).

3 Specifically, we found that betaCA5 had a first-order rate constant ~10-fold lower than betaCA1, a

4 yl carbonates 9 and 10, respectively, with a first-order rate constant (2-Bu(4)N: k = 18.5 +/- 0.1 x

5 e aquated (G/H(2)O) intermediate (4) (pseudo-first-order rate constant = (3.62 +/- 0.04) x 10(-5) s(-

6 howed a linear dependence between the pseudo-first-order rate constant and the pKa of the leaving gro

7 nments and, for each enzyme, extracted three first-order rate constants and their relative contributi

8 We measured pseudo-first-order rate constants and uptake coefficients based

9 nd Finfinity are the amplitude, the apparent first-order rate constant, and the fluorescence end poin

10 overall ChOOH and PLOOH to LDL with apparent first-order rate constants approximately 60 and approxim

11 The limiting first order rate constants are 160 and 4 s(-1).

12 The pseudo-first-order rate constants are not linearly related to t

13 The first-order rate constants are obtained from the literat

14 First-order rate constants at 293 K for exchange of the

15 es (I(2), RP(o)) are single-exponential with first order rate constant beta(CR).

16 The rate of appearance (with a pseudo-first-order rate constant ca. 10(-6) s-1) of tandem doub

17 f the beta-cyclodextrin concentration with a first-order rate constant, common to both RNA and DNA, o

18 The pseudo-first-order rate constant describing fluorescence decay

19 First-order rate constants describing distribution and e

20 could be resolved and occurred with a pseudo-first-order rate constant determined at 4 microM [125I]T

21 Second, the first order rate constant for ATP hydrolysis remains rel

22 The first order rate constant for ATPase activity exhibits a

23 The first order rate constant for conversion of the initial

24 The increase in the observed pseudo-first order rate constant for formation of the trimer, k

25 The estimated pseudo-first order rate constant for macroscopic blockade was 4

26 The first order rate constant for phosphorylation increases

27 The first order rate constant for splicing of this intein, w

28 Doxorubicin leakage can be described by first order rate constant for transport across the lipid

29 The first order rate constant for unwinding was reduced only

30 Subunit exchange experiments yield first order rate constants for dimer dissociation that r

31 First order rate constants for formation of MzII(a) and

32 The first order rate constants for inactivation (k2) of the

33 ents was evaluated by determining the pseudo first order rate constants for inhibition of CTP functio

34 The first order rate constants for mitochondrial depolarizat

35 The first order rate constants for the dissociation, k(off),

36 equilibrium dissociation constants (KD) and first- order rate constants for the mutant proteins.

37 p is the neutrophil concentration, g is the first-order rate constant for bacterial growth, and t is

38 The value of the first-order rate constant for conversion of the enzyme-s

39 In model studies it is shown that the first-order rate constant for decarboxylation can indeed

40 The pH dependence of the first-order rate constant for decay of the alpha-aminoac

41 tuent results in a 3400-fold increase in the first-order rate constant for deuterium exchange.

42 lf-reaction, the pH dependence of the pseudo-first-order rate constant for disappearance of the alpha

43 e for greater than 33 days, the value of the first-order rate constant for dissociation of E.[(3)H]GW

44 An inverse dependence of the first-order rate constant for effusion out of the protei

45 The pseudo-first-order rate constant for factor Xa inhibition by an

46 Mutation of Arg98 to lysine decreases the first-order rate constant for flavin reduction by 180-fo

47 ine as the amine substrate, the value of the first-order rate constant for flavin reduction decreases

48 The apparent first-order rate constant for free sulfhydryl loss (0.08

49 +/- 0.005 min-1) is similar to the apparent first-order rate constant for inactivation (0.067 +/- 0.

50 and 12.9 +/- 3.8 mM were determined for the first-order rate constant for inactivation and the disso

51 The pseudo-first-order rate constant for inactivation varied with p

52 P by Sp-NONOate, or Ki, was 0.47 mM, and the first-order rate constant for irreversible inhibition of

53 nstant for its reaction with N(3)(-) and the first-order rate constant for its reaction with the aque

54 tant of 1.1 x 10(4) M-1.s-1, compared to the first-order rate constant for LiPII reduction by VA.

55 ics, and that the dependence of the observed first-order rate constant for persulfide cleavage by DTT

56 nated and nonfluorinated octanoic acids; the first-order rate constant for PFOA removal was 0.030 h(-

57 account discrimination in binding and in the first-order rate constant for phosphodiester bond scissi

58 ificant seasonality (ANOVA, p < 0.05) of the first-order rate constant for primary biodegradation was

59 studies showed that T201A T4moH had a faster first-order rate constant for product formation than T20

60 ne results in a decrease in the value of the first-order rate constant for reduction of 35-fold and a

61 were used, k(exch) was equal to k(-)(2), the first-order rate constant for reversal of the acyl-enzym

62 (3) The first-order rate constant for the approach to steady-sta

63 nstant and a value of 221+/-36 s(-1) for the first-order rate constant for the associated conformatio

64 The first-order rate constant for the ATPgammaS-mediated iso

65 carboxylation kinetics, and the activity and first-order rate constant for the CA hydration reaction

66 The first-order rate constant for the change from K+ to Na+

67 The logarithm of the first-order rate constant for the change from Na+ to K+

68 The observed first-order rate constant for the change in energy trans

69 %, CK enzyme activity by 34%, and the pseudo first-order rate constant for the CK reaction by 50%.

70 show as much as an 18-fold variation in the first-order rate constant for the conformational change,

71 The first-order rate constant for the conversion of the init

72 The first-order rate constant for the conversion of the init

73 The first-order rate constant for the folding of the alpha s

74 Kinetic analyses show that the apparent first-order rate constant for the inactivation of CVB3 b

75 The first-order rate constant for the inactivation of the ty

76 The first-order rate constant for the reaction of 1 and 2 in

77 The D242S and D242E mutations reduced the first-order rate constant for the reaction of MnP compou

78 The F190V mutation increased the first-order rate constant for the reduction of compound

79 (PCP), we found it was clear that the pseudo-first-order rate constant for the reduction of resazurin

80 0) concentration of 300 microM, the apparent first-order rate constant for this process is approximat

81 a function of GdnHCl concentration yields a first-order rate constant for unfolding of (9.0 +/- 7.5)

82 At 4 degreesC, the first-order rate constant for uridylylation by UDP-gluco

83 ime (tau(i)), where tau(i)(-1) is the pseudo-first-order rate constant for water efflux.

84 based on goodness-of-fit criteria, included first-order rate constants for all disposition processes

85 concentrations and transfer processes using first-order rate constants for all processes known to be

86 Pseudo-first-order rate constants for amidine nitrosation in aq

87 the MuA-DNA complexes are preassembled, the first-order rate constants for both DNA cleavage and DNA

88 275 degrees C in the gas phase have provided first-order rate constants for cis,trans interconversion

89 s diastereomer in one DNA strand affects the first-order rate constants for cleavage in the unmodifie

90 The pseudo-first-order rate constants for cleavage of the thio anal

91 compound I reduction (k2app), and decreased first-order rate constants for compound II reduction (k3

92 First-order rate constants for deprotonation of the alph

93 Here, we have measured first-order rate constants for each key step in the reac

94 ndividual subunits were combined into single first-order rate constants for each subunit which were c

95 of 1,600 M(-)(1) x cm(-)(1)), with apparent first-order rate constants for formation and decay of ap

96 tibiotics were identified in terms of pseudo-first-order rate constants for formation of reactive spe

97 Apparent first-order rate constants for GSH/PHGPX-induced peroxid

98 The first-order rate constants for intramolecular associatio

99 (+)( )()from theoretical computations of the first-order rate constants for intramolecular electron t

100 In contrast, the first-order rate constants for MnPII reduction by Mn(II)

101 The apparent first-order rate constants for NADP(+) release and NADPH

102 in situ infrared spectroscopy provide pseudo-first-order rate constants for reactions with a variety

103 The pseudo-first-order rate constants for rebinding to the alpha an

104 The pseudo first-order rate constants for the aquation of 1 to 2 in

105 Pseudo-first-order rate constants for the demetalation (kobs) a

106 First-order rate constants for the enantiomerization of

107 We measured pseudo-first-order rate constants for the first nucleotide addi

108 The pseudo-first-order rate constants for the H5-catalyzed AT inhib

109 First-order rate constants for the inactivation process

110 Pseudo-first-order rate constants for the insertion into 1-DMSO

111 The observed first-order rate constants for the monoexponential (k(ob

112 rate in the Compound I species (K(bind)) and first-order rate constants for the oxidation reactions (

113 f high salt concentration (1 M NaCl), pseudo-first-order rate constants for the reaction of moenomyci

114 First-order rate constants for the reactions of ions wer

115 yst for the oxidation of NaBr with H(2)O(2), first-order rate constants for the selenoxide eliminatio

116 The first-order rate constants for the single and double mut

117 The first-order rate constants for the thermally induced tra

118 The pseudo-first-order rate constants for these systems were determ

119 molar absorptivity and fluence-based pseudo-first-order rate constants for transformation of the six

120 Moreover, although the apparent first-order rate constants for transmembrane ion flux in

121 The surface area-normalized pseudo-first-order rate constant, for example, associated with

122 The current-normalized pseudo-first-order rate constant has been estimated to be quite

123 gradation followed first-order kinetics, and first-order rate constants increased with increasing tem

124 The first-order rate constant increases with increasing [ATP

125 The pH-rate profile for the observed first-order rate constant is bell-shaped with two ioniza

126 y chromatography column by 10% if the pseudo-first-order rate constant is larger than 0.1 s(-1).

127 ht complex in the absence of MgATP (apparent first-order rate constant k = 0.007 s-1) and that MgATP

128 H/D KIE on the first-order rate constant k(cat) ((D)k = 3.72) has been

129 h ferrozine concentrations, and an effective first-order rate constant k(Fz) for the disappearance of

130 The first-order rate constant k(obs) was not affected by the

131 nd (3) a larger 320 000-fold decrease in the first-order rate constant k(s) for hydrolysis of this co

132 The observed first-order rate constants k(1)(25 degrees C) were found

133 , yield activation barriers DeltaG(ET)() and first-order rate constants k(ET) for electron-transfer b

134 A comparison of the first-order rate constants k(HO)[HO(-)] = 4.5 x 10(-11)

135 erature in high yield, and the corresponding first-order rate constants k(OH), k(Cl), and k(Br) are o

136 The first-order rate constant (k(2)) for formation of the ac

137 ng a normal 3',5'-linkage was cleaved with a first-order rate constant (k(2)) of 0.91 min(-)(1).

138 f selection show a >400-fold increase in the first-order rate constant (k(cat)) on a DNA substrate, r

139 (based on [(14)C]Ch transfer) increasing the first-order rate constant (k) approximately 7-fold.

140 First-order rate constants (k = 1.91-14.2 x 10(-5) s(-1)

141 Observed pseudo-first-order rate constants (k(obs)) of the hydride-trans

142 NTO and hydroquinone speciation, the pseudo-first-order rate constants (k(Obs)) varied by 3 orders o

143 The first-order rate constant, k(1)((ISP-f)), predicted from

144 The pseudo-first-order rate constants, k(obsd), are pH independent

145 eaction with a substrate in solution (pseudo-first-order rate constant, k1(f)), accounts for the impo

146 d intermediates autodecomposed slowly with a first order rate constant k2 = 0.003 min(-1); when a red

147 dissociation constant Kd of 13.3 mM and the first-order rate constant k2 of 0.22 s-1.

148 The apparent first-order rate constants (ka) of PBP2a acylation by be

149 diffusion constant corresponds to an average first-order rate constant kHOP of 2(+/-1) x 10(6) s(-1)

150 Observed pseudo-first-order rate constants (kobs) ranged from 3.8 x 10(-

151 resented in terms of the net observed pseudo-first-order rate constant, kobs, rather than in terms of

152 First-order rate constants kOP were 1,600 +/- 300 min-1

153 ific light attenuation is corrected for, the first-order rate constants kpdPAR, kpdUVA, and kpdUVB wi

154 Using PhoB in excess of P-VanS, a pseudo-first-order rate constant (kxfer) of 0.2 min-1 for phosp

155 n flux, with over 10-fold differences in the first-order rate constant manifested in molecular specie

156 ce of the substituent, as pointed out by the first-order rate constants measured at 25 degrees C.

157 Extrapolation of first-order rate constants measured at elevated temperat

158 Pseudo-first-order rate constant measurements were made for con

159 was informed by the development of a pseudo first-order rate constant model, and tested in a paper-b

160 360 nm decays in a biphasic manner with two first-order rate constants, neither of which are affecte

161 Pseudo-first-order rate constants obtained at -50 degrees C wit

162 the enzyme-TIMP-1 complex dissociates with a first order rate constant of 0.00026 s-1.

163 requiring MgATP hydrolysis, with an apparent first order rate constant of 0.02 s-1 compared with 140

164 oxorubicin dissolution can be described by a first order rate constant of 1.0x10(-9)cms(-1) at 37 deg

165 kyrin in resealed cells with a half-time and first order rate constant of 12 +/- 3.6 min and 0.060 +/

166 reduced by substrate and exhibits a limiting first order rate constant of 230 s(-1) at pH 7.5 and 30

167 19 decomposed back to the ferric form with a first order rate constant of 29.4 +/- 3.4 s(-1), which i

168 enous ankyrin from IOVs with a half-time and first order rate constant of 42 +/- 14 min and 0.017 +/-

169 The first order rate constant of C-terminal cleavage is 1.2

170 The pseudo first order rate constant of dithiothreitol-dependent N-

171 The calculated-first order rate constants of transformation, k, increas

172 quation of 1 to yield 2 occurs with a pseudo-first-order rate constant of (4.15 +/- 0.04) x 10(-5) s(

173 8 nM and reacts to the tight complex with a first-order rate constant of 0.003 s-1.

174 the 5'-deazaFAD reductase autoxidizes with a first-order rate constant of 0.007 s(-)(1).

175 followed single exponential kinetics, with a first-order rate constant of 0.2-0.5 s-1 at 24 degrees C

176 severs phalloidin-stabilized F-actin with a first-order rate constant of 0.25 s-1.

177 xhibited saturation behavior with a limiting first-order rate constant of 0.8 s(-1) and a K(d) of < o

178 and free Mn protoporphyrin IX occurs with a first-order rate constant of 1.2 x 10(-2) s(-1) at 20 de

179 urs 3 orders of magnitude more slowly with a first-order rate constant of 1.67 x 10(-5) s(-1).

180 the absence of NADPH-P450 reductase, with a first-order rate constant of 14 min(-1) at 25 degrees C.

181 h model phosphatidylcholine vesicles, with a first-order rate constant of 5.3 s-1 (t(1)/(2) = 130 ms)

182 enzyme-TPPS] complex of 1.3 10(4)mol/L and a first-order rate constant of 6.6 10(-1)s(-1) for dissoci

183 tterns for the pH dependence of k(bkdn), the first-order rate constant of breakdown, were found.

184 energy of 13.1 kcal mol(-1) , a high pseudo-first-order rate constant of CH(4) activation up to 2.8x

185 Tumor perfusion, as measured by the first-order rate constant of gadolinium plasma to tissue

186 nificantly increased values for the apparent first-order rate constant of inactivation.

187 which reacts with acetonitrile with a pseudo-first-order rate constant of k = 1 x 10(6) s(-1) and is

188 (4-) decayed to ground state products with a first-order rate constant of k = 2 x 10(3) s(-1).

189 alpha-pinene SOA was estimated, and a pseudo-first-order rate constant of k = 7.3 +/- 1.7 x 10(-3) s(

190 The pseudo-first-order rate constant of PS particles reacting with

191 s that lead to product as well as the pseudo-first-order rate constant of the reaction.

192 The first-order rate constant of the redox reaction between

193 presence and absence of heparin, the pseudo-first-order rate constant of thrombin inhibition (kobs)

194 1.2 +/- 0.4 and 8.2 +/- 0.05 and displaying first-order rate constants of <0.7 x 10(-6) s(-1) at pH

195 s of approximately 0.86 and 8.0 +/- 0.1 with first-order rate constants of <7 x 10(-6) s(-1) at pH va

196 Pseudo-first-order rate constants of 2-MeImpG and ImpG hydrolys

197 Q168R with UDP-glucose proceed with maximum first-order rate constants of 2.2 x 10(-)4 s-1 and 4.2 x

198 nzyme undergoes deuridylylation with maximum first-order rate constants of 4.8 x 10(-)4 s-1 and 1.68

199 parable, both being associated with apparent first-order rate constants of approximately 1 x 10(-)(4)

200 We show for the first time that the pseudo-first-order rate constants of fast bimolecular processes

201 We report experimentally determined first-order rate constants of MeHg photolysis in three w

202 The first-order rate constants of the solvolysis of sulfoniu

203 k(1) and k(-4) are the first-order rate constants of the transition induced by

204 of the hyperbolic dependence of the observed first-order rate constant on alpha,beta-methyleneadenosi

205 The saturable dependence of the observed first-order rate constants on the concentrations of AT i

206 An adjustable kinetic model that reduces the first-order rate constants proportional to neighboring g

207 ts ranged from 50 to 510 mg L(-1) d(-1), and first-order rate constants ranged from 60 to 400 d(-1),

208 B. thetaiotaomicron had larger first order rate constants than all other organisms unde

209 n initial lag phase and gave apparent pseudo-first order rate constants that increased with protein c

210 narrow range of values was observed for the first-order rate constant that describes lactate efflux,

211 Bi(2)O(3) combusts C(2)H(2) with a first-order rate constant that is 3000 times greater tha

212 of the core polymerase resulted in a set of first-order rate constants that varied in a hyperbolic m

213 biaryl compounds in quantitative yields with first-order rate constants that were independent of the

214 The pseudo first-order rate constant to regenerate the di-cobalt be

215 uilibration is known to be modulated by four first-order rate constants: two (T1a(-1) and T1b(-1)) fo

216 nce of distinguishable events and the pseudo-first-order rate constants under "standard" conditions (

217 rst-order kinetic model, resulting in pseudo-first-order rate constant values of 0.10, 0.12, 0.20, an

218 adenovirus receptor showed that the observed first-order rate constant varies with receptor concentra

219 Plots of the log of the observed first-order rate constant versus denaturant concentratio

220 Examination of the first-order rate constant versus enzyme concentration su

221 ned as the slopes of the plots of the pseudo-first-order rate constants versus the concentrations of

222 tive intermediates in CsX because the pseudo-first-order rate constant was nearly same for the two ma

223 , n = 10); however, the myocardial CK pseudo first-order rate constant was normal in LVH (0.36 +/- 0.

224 Pseudo-first-order rate constants were determined for the Fried

225 aturation behaviour when the observed pseudo first-order rate constants were plotted against NO2(-) c

226 re fitted to a first-order equation, and the first-order rate constants were plotted against the dNTP

227 le second-order mechanism and initial pseudo first-order rate constants which differ significantly fr