ライフサイエンスコーパス: flaccid

1 increase of 30% and 40% in mean diameter in flaccid and erectile states, respectively.

2 The clinical presentation of flaccid and often profound muscle weakness (which can in

3 serotypes A-G) and tetanus neurotoxin elicit flaccid and spastic paralysis, respectively.

4 In 9 days, flaccid areflexic quadriparesis and bulbar palsy develop

5 gnosed based on its clinical manifestations (flaccid blisters and erosions on skin and oral mucosa),

6 d day, the erythema had largely evolved into flaccid blisters, with epidermal detachment involving mo

7 tpg1-2 double mutant builds ~7-mum immotile flaccid cilia that completely lack dynein arms.

8 sitization of CC smooth muscle maintains the flaccid (contracted) state.

9 We hypothesize that the flaccid cortex of mhcA- cells cannot generate sufficient

10 nificant adhesive interaction to distort the flaccid cortex of mhcA- cells mhcA- cells were excluded

11 Flaccid giant liposomes showed no measurable elasticity.

12 Flaccid hearts (no left ventricular balloon) served as c

13 reement with aspiration measurements made on flaccid human erythrocytes, but the prestressed model al

14 terminal sequences lead to the production of flaccid, infertile eggs with a soluble, rather than inso

15 ne membrane as sV23 protein null mutants lay flaccid, infertile eggs.

16 ant cause of epidemic viral encephalitis and flaccid limb paralysis, yet the mechanism by which it en

17 Neurological deficits included flaccid limb weakness (n=10; asymmetric n=7), bulbar wea

18 Acute flaccid myelitis refers to acute flaccid limb weakness with spinal cord gray matter lesio

19 t toxic substances known to humankind, cause flaccid muscle paralysis by blocking acetylcholine relea

20 are the most potent of all toxins that cause flaccid muscle paralysis leading to death.

21 is characterised by episodes of often severe flaccid muscle paralysis, in which the muscle fibre memb

22 nsmitter acetylcholine, thereby resulting in flaccid muscle paralysis.

23 atients also suffer from hypotonia (weak and flaccid muscles) and balance problems.

24 ic health concerns due to outbreaks of acute flaccid myelitis (AFM) and encephalomyelitis in North Am

25 t coincide with a reported increase in acute flaccid myelitis (AFM) cases.

26 Since 2014, cases of acute flaccid myelitis (AFM) have been reported in the United

27 rus D68 (EV-D68) in 2014 as a cause of acute flaccid myelitis (AFM) in children are unknown.

28 ates of severe respiratory illness and acute flaccid myelitis (AFM) in children worldwide.

29 is associated with the development of acute flaccid myelitis (AFM) in children.

30 as been linked with the development of acute flaccid myelitis (AFM) in children.

31 s respiratory illness and is linked to acute flaccid myelitis (AFM) in infants and children.

32 Enterovirus D68 (EV-D68)-associated acute flaccid myelitis (AFM) is a devastating neurological dis

33 Acute flaccid myelitis (AFM) is a disabling, polio-like illnes

34 e summer/fall 2014, pediatric cases of acute flaccid myelitis (AFM) occurred in the United States, co

35 Acute flaccid myelitis (AFM) recently emerged in the United St

36 d biennial spikes in EV-D68-associated acute flaccid myelitis (AFM) that have left hundreds of childr

37 erienced a biennial spike in pediatric acute flaccid myelitis (AFM)(1-6).

38 fied as a cause of recent outbreaks of acute flaccid myelitis (AFM), a poliomyelitis-like spinal cord

39 ecedented spikes in pediatric cases of acute flaccid myelitis (AFM), which is a poliomyelitis-like pa

40 to neurological complications such as acute flaccid myelitis (AFM).

41 iratory illness and is associated with acute flaccid myelitis (AFM).

42 ed with severe respiratory disease and acute flaccid myelitis (AFM).

43 re respiratory and neurologic disease [acute flaccid myelitis (AFM)].

44 to severe neurological disease such as acute flaccid myelitis (EV-D68) and viral encephalitis (EV-A71

45 One child with acute flaccid myelitis and a sibling with only upper respirato

46 including poliomyelitis, myocarditis, acute flaccid myelitis and the common cold.

47 ssociation between enterovirus D68 and acute flaccid myelitis and the contention that acute flaccid m

48 th enterovirus D68 (EV-D68)-associated acute flaccid myelitis at the same hospital between 2013 and 2

49 ve for enterovirus D68 with those with acute flaccid myelitis but negative for enterovirus D68 using

50 rovirus D68 and the recent increase in acute flaccid myelitis cases in the United States.

51 o temporally and geographically linked acute flaccid myelitis clusters at the height of the 2014 outb

52 ebrospinal fluid from 14 patients with acute flaccid myelitis did not reveal evidence of an alternati

53 between enterovirus D68 infection and acute flaccid myelitis during the 2014 enterovirus D68 respira

54 ngs in children with EV-A71-associated acute flaccid myelitis during the study period with these find

55 erovirus D68 sequences associated with acute flaccid myelitis grouped into a clade B1 strain that eme

56 has been linked to the development of acute flaccid myelitis in children.

57 illness and a paralytic disease called acute flaccid myelitis in infants.

58 e main driver of epidemic outbreaks of acute flaccid myelitis in recent years(4), yet not much is kno

59 accid myelitis and the contention that acute flaccid myelitis is a rare yet severe clinical manifesta

60 and from 12 (48%) of 25 patients with acute flaccid myelitis overall.

61 Acute flaccid myelitis refers to acute flaccid limb weakness w

62 litis, children with EV-A71-associated acute flaccid myelitis were younger, showed neurological onset

63 Patients with acute flaccid myelitis who presented to two hospitals in Color

64 We compared patients with acute flaccid myelitis who were positive for enterovirus D68 w

65 io-like paralysis syndrome (now termed acute flaccid myelitis)(1-3).

66 disease (eg, meningitis, encephalitis, acute flaccid myelitis).

67 a, including meningitis, encephalitis, acute flaccid myelitis, and seizures) and enterovirus detected

68 d with children with EV-D68-associated acute flaccid myelitis, children with EV-A71-associated acute

69 re respiratory illness in children and acute flaccid myelitis, raising concerns about its potential i

70 ectrum of serious illnesses, including acute flaccid myelitis, severe respiratory complications, and

71 48 patients were included: 25 with acute flaccid myelitis, two with enterovirus-associated enceph

72 ifferences in clinical presentation of acute flaccid myelitis, we also used a subgroup analysis to co

73 ebilitating paralytic disease known as acute flaccid myelitis.

74 nfants and has recently been linked to Acute Flaccid Myelitis.

75 s of severe respiratory infections and acute flaccid myelitis.

76 ytic diseases such as poliomyelitis or acute flaccid myelitis.

77 llness and increased cases of nonpolio acute flaccid myelitis.

78 in a polio-like neurological disorder, acute flaccid myelitis.

79 %) children met our case definition of acute flaccid myelitis.

80 reported sporadically in patients with acute flaccid myelitis.

81 a spectrum of motility, from paralysis with flaccid or twitching flagella as other spoke mutants to

82 h a higher rate of reporting non-polio acute flaccid paralysis (AFP) (OR = 1.13, 95% CI 1.02-1.26 for

83 t noted an abnormal number of cases of acute flaccid paralysis (AFP) among adults, which were later c

84 Stool specimens of patients with acute flaccid paralysis (AFP) and sewage samples collected fro

85 In 1986, surveillance of acute flaccid paralysis (AFP) cases among children <15 years o

86 Polio cases were defined as acute flaccid paralysis (AFP) cases reported from 7 October to

87 Surveillance for acute flaccid paralysis (AFP) is a fundamental cornerstone of

88 n <36 mo old identified with non-polio acute flaccid paralysis (AFP) reported through polio surveilla

89 We used acute flaccid paralysis (AFP) surveillance data from Nigeria c

90 ES complements clinical acute flaccid paralysis (AFP) surveillance for possible polio

91 Gaps in acute flaccid paralysis (AFP) surveillance have been consisten

92 io enteroviruses (NPEVs) isolated from acute flaccid paralysis (AFP) surveillance in Shandong Provinc

93 tionnaires collected information about acute flaccid paralysis (AFP) surveillance resources, training

94 VAPP cases were identified using LAC's acute flaccid paralysis (AFP) surveillance system.

95 kistan during July 2009 to support the acute flaccid paralysis (AFP) surveillance system.

96 cle reviews the epidemiology of polio, acute flaccid paralysis (AFP) surveillance, and the implementa

97 ect process indicators associated with acute flaccid paralysis (AFP) surveillance, routine immunizati

98 lan as an activity that can complement acute flaccid paralysis (AFP) surveillance.

99 following immunisation (AEFI); ongoing acute flaccid paralysis (AFP) surveillance; active, hospital-b

100 A case of acute flaccid paralysis (AFP) was defined as a child <15 years

101 averaged only 57% and surveillance for acute flaccid paralysis (AFP) was suboptimal (AFP rate<1 per 1

102 1 isolates obtained from patients with acute flaccid paralysis (AFP) were compared by nucleotide sequ

103 Twenty-one cases of acute flaccid paralysis (AFP) were reported on the island of H

104 A case was defined as any case of acute flaccid paralysis (AFP) with virological confirmation of

105 ani and Afghani children with nonpolio acute flaccid paralysis (AFP).

106 35 South Asian children with nonpolio acute flaccid paralysis (AFP).

107 of South Asian children with nonpolio acute flaccid paralysis (AFP).

108 ted HFMD (n = 47), meningitis (n = 8), acute flaccid paralysis (n = 1), encephalitis (n = 21), and en

109 specimens from patients reported with acute flaccid paralysis and 3171 wastewater samples were teste

110 the release of neurotransmitters that cause flaccid paralysis and are considered potential bioweapon

111 d to assess a cluster of children with acute flaccid paralysis and cranial nerve dysfunction geograph

112 ally and temporally defined cluster of acute flaccid paralysis and cranial nerve dysfunction in child

113 ne depolarization, action potential failure, flaccid paralysis and cytopathology that are characteris

114 eins required for neurotransmission, causing flaccid paralysis and death by asphyxiation.

115 caviruses in human diseases, including acute flaccid paralysis and diarrhea, will require further epi

116 er investigators that highlighted persistent flaccid paralysis and electrophysiological evidence of a

117 self-limiting acute febrile illness to acute flaccid paralysis and lethal encephalitis.

118 irulent variants exhibiting polio-like acute flaccid paralysis and other central nervous system manif

119 of a surveillance system for cases of acute flaccid paralysis and poliovirus infection.

120 Using acute flaccid paralysis and routine, monthly countrywide envir

121 al features of the increasing cases of acute flaccid paralysis associated with anterior myelitis note

122 e of human motor neurons are responsible for flaccid paralysis associated with botulism.

123 children aged 0-14 years with onset of acute flaccid paralysis between Jan 1, 2001, and Dec 31, 2011.

124 ) is a highly potent neurotoxin that elicits flaccid paralysis by enzymatic cleavage of the exocytic

125 oteases that cleave SNARE proteins to elicit flaccid paralysis by inhibiting neurotransmitter-carryin

126 oteases that cleave SNARE proteins to elicit flaccid paralysis by inhibiting the fusion of neurotrans

127 linum toxin (BT) is a neurotoxin that causes flaccid paralysis by inhibiting the release of acetylcho

128 An analysis was conducted of 10,486 acute flaccid paralysis cases diagnosed as Guillain-Barre synd

129 ean numbers of infected and uninfected acute flaccid paralysis cases investigated in a season are der

130 like poliovirus isolates from Nigerian acute flaccid paralysis cases obtained from routine surveillan

131 lic Health received several reports of acute flaccid paralysis cases of unknown etiology.

132 nvestigated the mechanism of temporary acute flaccid paralysis caused by Zika virus infection in aged

133 nergic nerve terminals, causing a descending flaccid paralysis characteristic of the disease botulism

134 tates between 2009 and 2014, using the acute flaccid paralysis database at the World Health Organizat

135 rable outcomes, although patients with acute flaccid paralysis did not recover limb strength.

136 as compared with that of children with acute flaccid paralysis due to other causes to estimate the cl

137 West Nile encephalitis; a poliomyelitis-like flaccid paralysis due to West Nile virus was recognised,

138 23 August 1991, a 2-year-old boy with acute flaccid paralysis due to wild poliovirus was detected in

139 meeting diagnostic criteria for other acute flaccid paralysis etiologies were excluded.

140 Since then, >9000 cases of acute flaccid paralysis have been reported and thoroughly inve

141 documented in 27 percent of the patients and flaccid paralysis in 10 percent; in all of the latter, n

142 in 20 (35%), encephalitis in 6 (11%), acute flaccid paralysis in 4 (7%), and autonomic dysregulation

143 in stool collected from children with acute flaccid paralysis in Africa.

144 cribed as a bilateral, symmetric, descending flaccid paralysis in an afebrile and alert patient witho

145 ism manifests with cranial nerve palsies and flaccid paralysis in children and adults.

146 dium botulinum (Clb), the causative agent of flaccid paralysis in humans that can be fatal in 5 to 10

147 emics of meningitis, encephalitis, and acute flaccid paralysis in humans.

148 wild poliovirus and cases of non-polio acute flaccid paralysis in India.

149 MP2 and VAMP4 in cultured neurons and causes flaccid paralysis in mice.

150 here has been limited surveillance for acute flaccid paralysis in North America since the regional er

151 Case series of acute flaccid paralysis in patients with radiological or neuro

152 erosurvey was conducted among cases of acute flaccid paralysis in the 25 high-polio-incidence distric

153 us system, is the most common cause of acute flaccid paralysis in the post-polio era.

154 d in 12 of 192 patients with non-polio acute flaccid paralysis in Tunisia and Nigeria and 0 of 96 hea

155 ingitis, and concomitant muscle weakness and flaccid paralysis may provide a clinical clue to the pre

156 pisodes), oculogyric crisis (four episodes), flaccid paralysis of all extremities (four episodes), tr

157 m is characterized by symmetric, descending, flaccid paralysis of motor and autonomic nerves, usually

158 lysis (hypoKPP) is characterized by episodic flaccid paralysis of muscle and acute hypokalemia during

159 sure for botulism, a fatal illness caused by flaccid paralysis of muscles due to botulinum neurotoxin

160 BoNT/A application causes long-lasting flaccid paralysis of muscles through inhibiting the rele

161 Clusters of acute flaccid paralysis or cranial nerve dysfunction in childr

162 Patients initially seen with acute flaccid paralysis or pulmonary edema had significantly g

163 Surveillance for cases of acute flaccid paralysis provides a means for detecting circula

164 dose of OPV among 47 574 children with acute flaccid paralysis reported during 2005-2009.

165 s of stool samples taken from cases of acute flaccid paralysis revealed the presence of mixtures of r

166 posed national surveillance system for acute flaccid paralysis should capture at a minimum the 796 GB

167 , the importance of maintaining strong acute flaccid paralysis surveillance even in adults, and the n

168 We conducted a retrospective review of acute flaccid paralysis surveillance in the security-compromis

169 lected from children identified by the acute flaccid paralysis surveillance program in India during 2

170 from among cases reported through the acute flaccid paralysis surveillance system between November 2

171 r understanding the sensitivity of the acute flaccid paralysis surveillance system is presented by fi

172 Health Organization requested that the acute flaccid paralysis surveillance system of Latin American

173 The acute flaccid paralysis surveillance system represents a usefu

174 A robust acute flaccid paralysis surveillance system, including a multi

175 supplementary immunization activities, acute flaccid paralysis surveillance, and routine immunization

176 f field teams, (3) field work, and (4) acute flaccid paralysis surveillance.

177 cted in Bangladesh in 2007 to 2008 for acute flaccid paralysis surveillance.

178 ages of human resources and strengthen acute flaccid paralysis surveillance.

179 levamisole: an initial spastic paralysis; a flaccid paralysis that follows; and finally, a recovery

180 rus developed motor deficits including acute flaccid paralysis that peaked 8-10 days after viral chal

181 Botulinum neurotoxins (BoNTs) elicit flaccid paralysis through cleavage of SNARE proteins wit

182 e zinc proteases (serotypes A-G) which cause flaccid paralysis through the cleavage of SNARE proteins

183 Botulinum neurotoxin causes rapid flaccid paralysis through the inhibition of acetylcholin

184 A peripheral flaccid paralysis was found to occur, before or concurre

185 nce database, in which 27,379 cases of acute flaccid paralysis were recorded between 2001 and 2007.

186 icated a rare but distinct syndrome of acute flaccid paralysis with evidence of spinal motor neuron i

187 AE in rodents typically results in ascending flaccid paralysis with inflammation primarily targeting

188 rodents is manifested typically as ascending flaccid paralysis with inflammation targeting the spinal

189 ibe a group of patients with acute segmental flaccid paralysis with minimal or no encephalitic or sen

190 apon would cause acute symmetric, descending flaccid paralysis with prominent bulbar palsies such as

191 spital Colorado (Aurora, CO, USA) with acute flaccid paralysis with spinal-cord lesions involving mai

192 rome (GBS) is the most common cause of acute flaccid paralysis worldwide, and is thought to be immune

193 ive disease (meningitis, encephalitis, acute flaccid paralysis) develops in less than 1% but carries

194 ncluding neonatal sepsis-like disease, acute flaccid paralysis, and acute hemorrhagic conjunctivitis.

195 hagic disease, encephalitis, biphasic fever, flaccid paralysis, and jaundice are typical manifestatio

196 polio vaccine (OPV), surveillance for acute flaccid paralysis, and OPV "mop-up" campaigns.

197 , including myocarditis, pancreatitis, acute flaccid paralysis, and poliomyelitis.

198 aseptic meningitis, poliomyelitis-like acute flaccid paralysis, brainstem encephalitis, and other sev

199 vascular shock syndrome, encephalitis, acute flaccid paralysis, congenital abnormalities and fetal de

200 d population groups, and surveillance (acute flaccid paralysis, enterovirus, and environmental) needs

201 After an initial contralateral flaccid paralysis, motor function rapidly recovered, aft

202 in humans ranges from sub-clinical to acute flaccid paralysis, myocarditis and meningitis.

203 e release at neuromuscular junctions causing flaccid paralysis, specifically synaptosomal-associated

204 While BoNTs cause flaccid paralysis, TeNT causes spastic paralysis.

205 Botulism is characterized by flaccid paralysis, which can be caused by intoxication w

206 s act locally within motor neurons to elicit flaccid paralysis, while retrograde TeNT traffics to inh

207 Timely investigation of children with acute flaccid paralysis, with collection of stool specimens fo

208 utants move poorly, exhibiting an incomplete flaccid paralysis, yet have normal muscle ultrastructure

209 on causes long-lasting and potentially fatal flaccid paralysis-a major feature of botulism.

210 3 and early 2014 in the absence of any acute flaccid paralysis.

211 re neurological complications, such as acute flaccid paralysis.

212 sting stool samples from patients with acute flaccid paralysis.

213 naptic vesicle (SV) exocytosis, resulting in flaccid paralysis.

214 ation coverage from data for non-polio acute flaccid paralysis.

215 phalitis, and 3 had poliomyelitis-like acute flaccid paralysis.

216 s conducting surveillance for cases of acute flaccid paralysis.

217 ose IPV (fIPV) as a measure to prevent acute flaccid paralysis.

218 ated calcium channels and to an irreversible flaccid paralysis.

219 pulation immunity and prevent cases of acute flaccid paralysis.

220 esents as encephalitis, meningitis, or acute flaccid paralysis.

221 ausation or recovery from ZIKV-induced acute flaccid paralysis.

222 s investigated during surveillance for acute flaccid paralysis.

223 myelitis, a condition characterized by acute flaccid paralysis.

224 romes of meningitis, encephalitis, and acute flaccid paralysis/poliomyelitis.

225 sm (WB) is a potentially lethal, descending, flaccid, paralysis that results when spores of Clostridi

226 ute encephalomyeloradiculitis had a moderate flaccid paraparesis, and the patient with subacute menin

227 and, after 6 months, culminated in areflexic flaccid quadriplegia.

228 Sharper lateral inflection in the flaccid rather than the tense LR seems inconsistent with

229 For a flaccid red cell, we show that the total adhesion energy

230 h RhoA-mediated Ca(2+) sensitization, to the flaccid state of CC that can be reversed by a water-solu

231 inct signs of CNS disease that ranged from a flaccid tail to complete paralysis of hind limbs.

232 yed, the clinical signs will ascend, causing flaccid tetraparesis and other lower motor neuron signs.

233 h poorly contractile smooth muscle, wrinkled flaccid ventral abdominal wall with skeletal muscle defi

234 ation of the latter drugs, most had diffuse, flaccid weakness with failure to wean from mechanical ve