ライフサイエンスコーパス: flagellum

1 single-celled eukaryote with a single cilium/flagellum.

2 FliG in the cytoplasmic C ring rotor of the flagellum.

3 is disrupted at 0.8 mum intervals along the flagellum.

4 us load experienced by the motor through the flagellum.

5 forces that deform the cross-section of the flagellum.

6 ed in components of the cytoskeleton and the flagellum.

7 resulting from a buckling instability of the flagellum.

8 nesin-13 in Giardia, along the length of the flagellum.

9 e for its targeting to and enrichment in the flagellum.

10 lecules consumed per beat of a demembranated flagellum.

11 nsing, which involves the rotating bacterial flagellum.

12 s, which generates propulsive bending of the flagellum.

13 tokinesis but are able to traffic GT1 to the flagellum.

14 ticipate in the function of its single polar flagellum.

15 e-unit genome is physically connected to the flagellum.

16 l positions in addition to the primary polar flagellum.

17 alcium channel is activated in the mammalian flagellum.

18 usly detecting the rotational states of each flagellum.

19 e mitochondrial DNA to the basal body of the flagellum.

20 sion of flagellar genes with assembly of the flagellum.

21 anterior kinetoplast was associated with the flagellum.

22 model into oval amastigotes with no external flagellum.

23 t it can extend without impinging on the old flagellum.

24 d tmAC in the head and Adcy10 and PKA in the flagellum.

25 ng to detachment and release of the parasite flagellum.

26 e by an export machinery at the base of each flagellum.

27 iving the ion-driven rotation of the helical flagellum.

28 bpellicular microtubules and the base of the flagellum.

29 e nucleation of axonemal microtubules in the flagellum.

30 ques they face when moving down the spinning flagellum.

31 correctly identify and track the motion of a flagellum.

32 tokinesis by activating motility of the male flagellum.

33 e junction to the microtubules in the mature flagellum.

34 key functional attribute of this spirochete flagellum.

35 positioned close to the base of the swimming flagellum [4, 5], demonstrating this is a photoreceptive

36 Archaea swim using the archaellum (archaeal flagellum), a reversible rotary motor consisting of a to

37 In the sperm flagellum, a single chemoattractant molecule can trigger

38 For self-assembly of the bacterial flagellum, a specific protein export apparatus utilizes

39 cialized cytoskeletal structure required for flagellum adhesion and cell morphogenesis.

40 gellum attachment zone filament assembly for flagellum adhesion and cytokinesis initiation.

41 The gp72 glycoprotein is associated with the flagellum adhesion zone on the parasite surface, and its

42 w abundance glycoprotein associated with the flagellum adhesion zone, called gp72.

43 is a cytoskeletal protein located within the flagellum along the flagellar attachment zone (FAZ).

44 single evolutionary origin of the eukaryotic flagellum, an origin that dates back to before the diver

45 P1 by co-localization with antibodies to the flagellum and acidocalcisomes, respectively.

46 o key fungal characters in Opisthokonta, the flagellum and chitin synthases.

47 iation of IFT-A and IFT-B at the base of the flagellum and flagellar import of IFT-A.

48 hat of the functionally equivalent bacterial flagellum and flagellar motor.

49 g process involves an increase in cell body, flagellum and flagellum attachment zone length and is ac

50 PA2982 led to non-polar localization of the flagellum and FlhF, which was thought to sit at the top

51 carrying cargoes from the cell body into the flagellum and from the flagellum back to the cell body.

52 Although the flagellum and injectisome serve different purposes, they

53 is located in the sperm head rather than the flagellum and is controlled by intracellular pH, but not

54 We show that Slo1 is localized to the sperm flagellum and is inhibited by progesterone.

55 his article, the equations of motion for the flagellum and its doublets are derived from mechanical e

56 flagellum prevented entry of IFT-A into the flagellum and led to severely decreased IFT injection fr

57 itochondrial genome to the basal body of the flagellum and mediates the segregation of the replicated

58 retory and endocytic organelles but also the flagellum and nucleus.

59 s two types of motility structures, a single flagellum and one or two clusters of type IV pili, to th

60 te the holdfast synthesis machinery with the flagellum and pili.

61 tSper, is expressed exclusively on the sperm flagellum and regulates sperm motility.

62 rter FAZ associated with a longer unattached flagellum and repositioned kinetoplast and basal body, r

63 tomonad can either remain attached or grow a flagellum and resume swimming.

64 roteins sufficient to assemble a half-length flagellum and that assembly of full-length flagella requ

65 clude that there are multiple ways to form a flagellum and that species-specific structural knowledge

66 a demonstrate that surface attachment by the flagellum and the flagellar pocket, a Leishmania-like fl

67 ternal cellular projections: the hook of the flagellum and the injectisome needle.

68 rotein ligands, including flagellin from the flagellum and the needle protein PrgI from the S. Typhim

69 trically during cytokinesis allowing the new-flagellum and the old-flagellum daughters to be distingu

70 more detailed model incorporating a helical flagellum and the rotational degrees of freedom of the c

71 embly of multiprotein complexes, such as the flagellum and the stalk and the correct positioning of r

72 ctor at the tip of an assembling trypanosome flagellum and three constituents of the axonemal capping

73 he GDP-locked version is unable to enter the flagellum and to interact with other IFT-B proteins and

74 ellum distinguish it from both the bacterial flagellum and type IV pili.

75 d TbCentrin3 form a complex, localize to the flagellum, and are required for viability in the bloodst

76 ed in the cytoplasm, reaches the base of the flagellum, and associates with the IFT machinery in a ma

77 motors generate sliding forces that bend the flagellum, and bending leads to deformations and stresse

78 m attachment zone filament, detached the new flagellum, and caused defective cytokinesis.

79 had a short, wide body, a very long anterior flagellum, and either one or two kinetoplasts, but only

80 protein FliD, is localized at the tip of the flagellum, and is essential for filament assembly, as we

81 g forces, regulation by the curvature of the flagellum, and regulation by the normal forces that defo

82 the machinery used to assemble the bacterial flagellum, and the needle complex many Gram-negative pat

83 onal degrees of freedom of the cell body and flagellum, and we use numerical simulations to map out t

84 s encoding a type III secretion system and a flagellum apparatus are transiently up-regulated while e

85 s in the midpiece and principal piece of the flagellum are distinctively different.

86 anism of this remodeling and the fate of the flagellum are obscure.

87 3 secretion system (T3SS) and the bacterial flagellum are related pathogenicity-associated appendage

88 nsight into the versatility of the bacterial flagellum as a secretory machine that can export protein

89 Vibrio, Proteus and Caulobacter that use the flagellum as a surface sensor.

90 regulate the internal motors that shape the flagellum as it beats.

91 ral processing role for TbRP2 in trypanosome flagellum assembly and challenge the notion that TbRP2 f

92 lar processes, including envelope integrity, flagellum assembly and protein quality control.

93 nemes, or general vesicular trafficking in a flagellum assembly context.

94 hful duplication and segregation of multiple flagellum-associated cytoskeletal structures, including

95 retion proteins (PopD, PcrV, and ExoS) and a flagellum-associated protein (FliD).

96 ms along magnetic field lines using a single flagellum at each cell pole.

97 Marine bacteria often swim with a single flagellum at high speeds, alternating "runs" with either

98 nd transitions to a canonical membrane-bound flagellum at the 'flagellar pore'.

99 transitions by regulating the length of the flagellum attachment zone (FAZ) filament, a specialized

100 rectionally from the anterior tip of the new flagellum attachment zone (FAZ) toward the posterior end

101 olecule entry into the FP and nucleating the flagellum attachment zone (FAZ), which adheres the flage

102 flagellum to the cell body, mediated by the flagellum attachment zone (FAZ).

103 role in promoting basal body segregation and flagellum attachment zone filament assembly for flagellu

104 ed basal body segregation, disrupted the new flagellum attachment zone filament, detached the new fla

105 g the hook complex, the centrin arm, and the flagellum attachment zone filament.

106 lves an increase in cell body, flagellum and flagellum attachment zone length and is accompanied by a

107 zation of two trypanosome-specific proteins, flagellum attachment zone tip-localizing protein require

108 and the flagellar pocket, a Leishmania-like flagellum attachment zone, and a Trypanosoma cruzi-like

109 orphology, including the flagella connector, flagellum attachment zone, and bilobe structure.

110 protein CAAP1, inhibited the assembly of the flagellum attachment zone, and caused flagellum misposit

111 rement for the assembly and extension of the flagellum attachment zone, which adheres the flagellum t

112 ze to the distal tips of the new and the old flagellum attachment zones and are required for cytokine

113 ys multiple roles in basal body segregation, flagellum attachment, and cytokinesis.

114 t secondary metabolites can disrupt parasite flagellum attachment, revealing a mechanism behind their

115 he cell body into the flagellum and from the flagellum back to the cell body.

116 y a type III export machinery located at the flagellum base, after which subunits transit through a n

117 P) can be markedly more complex than related flagellum-based chemotaxis systems.

118 tics during the early stage of recovery; (2) flagellum-based motility in the mid to late stage of rec

119 We confirm that flagellum-based motility is involved in, but is not abso

120 We report that flagellum-based motility similarly contributes to pellic

121 Further, we show that flagellum-based motility, chemotaxis and oxygen sensing

122 s work, we characterize the contributions of flagellum-based motility, chemotaxis and oxygen sensing

123 agellar rotation, accompanied by a decreased flagellum-based motility.

124 ece, middle piece and principal piece of the flagellum between testicular and epididymal spermatozoa.

125 ng the axoneme central pair apparatus and in flagellum biogenesis.

126 Mutants defective in the polar flagellum biosynthesis FliAP sigma factor also outcompet

127 erkinsela sp. has lost the ability to make a flagellum but retains hallmark features of kinetoplastid

128 the phage particle in docking to a host cell flagellum, but the identity of the protein that generate

129 egulates the length of both the T3SS and the flagellum, but the molecular basis for this length contr

130 of extending microtubules of the assembling flagellum by a kinesin-15 family member.

131 ivery of flagellin, the major subunit of the flagellum, by bacterial secretion systems.

132 ue to the rotation of the trailing (leading) flagellum can account for these observations.

133 Depending on length, a flagellum can switch between these regimes.

134 tivation of multiple genes, including in the flagellum-chemotaxis pathway.

135 ctions in motility and the expression of the flagellum-chemotaxis regulon between these clinically re

136 While all sterols are enriched in the flagellum, cholesterol is especially enriched.

137 The distal end of the eukaryotic flagellum/cilium is important for axonemal growth and si

138 Each flagellum consists of a basal body, a hook, and a filame

139 The bacterial flagellum contains a specialized secretion apparatus in

140 Calcium in the flagellum controls sperm navigation.

141 nces between the two daughters, with the new-flagellum daughter in particular re-modelling rapidly an

142 The old-flagellum daughter undergoes a different G1 re-modelling

143 nesis allowing the new-flagellum and the old-flagellum daughters to be distinguished.

144 We discovered that flagellum de- and repolarization in the model prokaryote

145 imorphic motile bacterium well known for its flagellum-dependent swarming motility over surfaces.

146 heavy chains and of DLI1 at the base of the flagellum depends on the intermediate dynein chain DIC5

147 we show that this subcomplex persists after flagellum disassembly in other phyla as well.

148 L rings persists in the outer membrane after flagellum disassembly.

149 oxylipins derived from this activity inhibit flagellum-driven motility and upregulate type IV pilus-d

150 P. aeruginosa GcbA was found to regulate flagellum-driven motility by suppressing flagellar rever

151 regulation of initial surface attachment and flagellum-driven motility, GcbA and the phosphodiesteras

152 The bacterial flagellum exemplifies a system where even small deviatio

153 The Campylobacter jejuni flagellum exports both proteins that form the flagellar

154 portance of ECA for cell envelope integrity, flagellum expression, and resistance of enteric bacteria

155 into the structures occurs very early during flagellum extension.

156 e also demonstrate that the native C. jejuni flagellum filament is 11-stranded, contrary to a previou

157 tron microscopy showed that 2D6 IgA promoted flagellum-flagellum cross-linking, as well as flagellar

158 , like S. Typhimurium, requires a functional flagellum for epithelial cell invasion and macrophage up

159 Many bacteria use the flagellum for locomotion and chemotaxis.

160 ization and virulence factors to exploit the flagellum for their own secretion.

161 in flagella, SAS6L was absent during gamete flagellum formation.

162 -B proteins and its sole expression prevents flagellum formation.

163 The periodic beating of an isolated flagellum from Chlamydomonas reinhardtii exhibits probab

164 er the flagellar membrane, detachment of the flagellum from the cell body, and disruption of mitotic

165 important biophysical questions of sheathed-flagellum function.

166 vestigated the consequences of TviA-mediated flagellum gene regulation on flagellin-specific CD4 T ce

167 In many species, Ca(2+) bursts in the flagellum govern navigation to the egg.

168 As the flagellum grows longer, diffusion delays return of kines

169 life cycle forms of this parasite during new flagellum growth and cytokinesis.

170 nd unanticipated mechanism for constant rate flagellum growth.

171 The flagellum has been recognized as an "antenna" that plays

172 Here we present a fully-automated method of flagellum identification from videomicroscopy based on t

173 emonstrate that the rotation of the sheathed flagellum in both the mutualist Vibrio fischeri and the

174 ing of micro organisms with a single helical flagellum in circular channels.

175 As an application of GLLM, swimming of flagellum in fluid is simulated and propulsive force as

176 n rat and the centrosome of the spermatozoon flagellum in humans, suggesting a common mechanism of ac

177 Inheritance of the newly assembled flagellum in the human parasite Trypanosoma brucei depen

178 his system has no homology to the eukaryotic flagellum, in which the filament alone, composed of a mi

179 In this study, we show how flagellum-independent migration is driven by the divisio

180 tructural or functional defects of the sperm flagellum induce asthenozoospermia, which accounts for t

181 uction of curvature in one part of a passive flagellum induces a compensatory countercurvature elsewh

182 This disruption renders the proximal flagellum inflexible and alters the 3D flagellar envelop

183 ok complex-centrin arm structure facilitates flagellum inheritance.

184 H2 that plays an essential role in promoting flagellum inheritance.

185 dividual sea urchin sperm with demembranated flagellum inside water-in-oil emulsion droplets and meas

186 s to adherence is unknown beyond ionic lipid-flagellum interactions in plant cell membranes.

187 mammalian host, Trypanosma cruzi discards it flagellum into the cytoplasm of the host cell.

188 The flagellum is a complex bacterial nanomachine that requir

189 The bacterial flagellum is a complex self-assembling nanomachine that

190 The flagellum is a major virulence factor of motile pathogen

191 The bacterial flagellum is a motile organelle driven by a rotary motor

192 In Salmonella, the rod substructure of the flagellum is a periplasmic driveshaft that couples the t

193 The bacterial flagellum is a remarkable molecular motor, whose primary

194 The flagellum is a rotary motor that enables bacteria to swi

195 We explored how the C. jejuni flagellum is a versatile secretory organelle by examinin

196 Ubiquitous in eukaryotic organisms, the flagellum is a well-studied organelle that is well-known

197 The elastic flagellum is actuated by a preferred curvature model tha

198 The function of the L-ring in the mature flagellum is also thought to act as a bushing for the ro

199 The bacterial flagellum is an amazing nanomachine.

200 The bacterial flagellum is an organelle that self-assembles outside th

201 The bacterial flagellum is assembled by a multicomponent transport app

202 The bacterial flagellum is assembled from over 20 structural component

203 secretion of proteins that assemble into the flagellum is driven by the proton motive force.

204 force (torque) generated at the base of the flagellum is essential for motility, niche colonization,

205 The assembly of the bacterial flagellum is exquisitely controlled.

206 The flagellum is one of relatively few biological machines t

207 Rotation of the bacterial flagellum is powered by a proton influx through the pept

208 results of severing experiments, in which a flagellum is regenerated after it has been severed.

209 more than an order of magnitude; the beating flagellum is simply unable to draw enough water through

210 The bacterial flagellum is the principal organelle of motility in bact

211 The bacterial flagellum is the prototypical protein nanomachine and co

212 The sole cAMP source in the flagellum is the soluble adenylate cyclase (SACY).

213 the experimental observation that a beating flagellum is usually longer than its immotile mutant.

214 ds, which are propelled by a single anterior flagellum, is characterized by a generalized helical mot

215 Here we analyse flagellum length, structure and molecular composition ch

216 a swimming motility screen to identify polar flagellum localization factors and discovered three gene

217 Short-term callunene exposure induced flagellum loss in C. bombi choanomastigotes, resulting i

218 ly over the increasing length of the growing flagellum, maintaining a constant rate of subunit delive

219 xhibit spermiogenic arrest with acrosome and flagellum malformation.

220 ssociated with the lateral attachment of the flagellum) may be an adaptation associated with the bloo

221 Flagellum mediated motility is an essential trait for rh

222 of the flagellum attachment zone, and caused flagellum mispositioning and detachment.

223 on morphological abnormalities of the sperm flagellum (MMAF), a phenotype also termed "short tails,"

224 res flagellum motility-generated forces, but flagellum motility exerts distinct effects between diffe

225 Cell division requires flagellum motility-generated forces, but flagellum motil

226 on, and provided molecular insights into the flagellum motility-mediated cytokinesis initiation in th

227 ariation in cell body helical parameters and flagellum number among H. pylori strains leading to dist

228 corporating variation of both cell shape and flagellum number predicts qualitative speed differences

229 Mutational perturbation of flagellum number revealed a 19% increase in speed with 4

230 19% increase in speed with 4 versus 3 median flagellum number.

231 , we identify CatSper Ca(2+) channels in the flagellum of A. punctulata sperm.

232 gulated entry of a membrane protein into the flagellum of Chlamydomonas, we show that cells use an IF

233 per, and we identify the Slo3 protein in the flagellum of human sperm.

234 intersegmental membrane between pedicel and flagellum of the antenna and line up in a ring-like orga

235 e transporter is selectively targeted to the flagellum of the kinetoplastid parasite Leishmania mexic

236 tional modules (e.g., biosynthesis of stalk, flagellum, or chemotaxis machinery) have consistent but

237 itment of CP assembly factors to the TZ, and flagellum paralysis.

238 ng UV light and white light drives the robot flagellum periodically to swing to eventually push forwa

239 he hook protein connecting the cell body and flagellum play a role in locomotion.

240 the rotary motor that rotates each bacterial flagellum, powering the swimming and swarming of many mo

241 teraction within the pool at the base of the flagellum prevented entry of IFT-A into the flagellum an

242 uorescens SBW25 that was revealed only after flagellum production was eliminated by deletion of the m

243 n SAS6, has been characterised recently as a flagellum protein in trypanosomatids, but associated wit

244 During assembly of the bacterial flagellum, protein subunits that form the exterior struc

245 erface between the two main functions of the flagellum-protein secretion and rotation.

246 mRNAs including those encoding acrosome and flagellum proteins.

247 In the reverse mode, when the flagellum pulls the cell, the precession is smaller and

248 In the forward mode, when the flagellum pushes the cell, the cell body is tilted with

249 and how these changes power rotation of the flagellum remain unknown.

250 tecting antibodies against Salmonella LPS or flagellum, resulting in a high false-positive rate.

251 tes shows that defensin alpha-1 binds to the flagellum, resulting in flagellar membrane and axoneme a

252 rongly reclival, and antenna with homonomous flagellum, revealing new and important details in antenn

253 ts suggest B. subtilis senses restriction of flagellum rotation as the cell nears a surface.

254 is a process that often uses obstruction of flagellum rotation to trigger behaviors such as adhesion

255 Using mutants of B. subtilis that prevent flagellum rotation, they measured the expression and act

256 d into a thin attachment pad associated with flagellum shortening.

257 lex cytoskeletal structure that connects the flagellum skeleton through two membranes to the cytoskel

258 icated basal bodies, which positions the new flagellum so that it can extend without impinging on the

259 le of FlgM is to inhibit FliA (sigma(28)), a flagellum-specific RNA polymerase responsible for flagel

260 Phenotyping revealed differences in flagellum structure, strain motility and immunogenicity,

261 m and the tiny spermatozoa lacking a visible flagellum, suggest they belong to a new genus, possibly

262 oglycan (PG)-binding stator protein from the flagellum, suggesting it might serve a similar role in T

263 ) captured bacteria with a collar complex, a flagellum surrounded by a microvillar collar.

264 nvolved in citrate transport and metabolism, flagellum synthesis, and chemotaxis.

265 mpartment: TbAK1 is exclusively found in the flagellum, TbAK2 in the glycosome, and TbAK3 in the cyto

266 self-assembling nanomachines: the bacterial flagellum that enables cells to propel themselves throug

267 site is highly polarized, including a single flagellum that is nucleated at the posterior of the cell

268 Coluber constrictor) and coachwhips (Coluber flagellum) that indicated the probability of competitive

269 n linear quadrilateral nanodomains along the flagellum, the complex lacking CatSperzeta is disrupted

270 regions of the cytoskeleton: the base of the flagellum, the subpellicular microtubules, and the mitot

271 bility relative to the thrust exerted by the flagellum; this parameter and the geometric parameters o

272 Specific flagellum tip structures exist, yet their composition, d

273 by rounds of subunit crystallization at the flagellum tip, and polymer theory predicts that as the N

274 rse the hollow filament and exit the growing flagellum tip.

275 bility of both viable C. jejuni and purified flagellum to bind to Siglec-10, an immune-modulatory rec

276 through a narrow channel at the core of the flagellum to reach the assembly site at the tip of the n

277 a complex that assembles at the base of the flagellum to regulate protein composition and cilium fun

278 cell shape is the lateral attachment of the flagellum to the cell body, mediated by the flagellum at

279 he flexibility of the hook that connects the flagellum to the cell body.

280 flagellum attachment zone, which adheres the flagellum to the cell surface, and for the rotation of t

281 tial organelles that position and adhere the flagellum to the cell surface.

282 lum attachment zone (FAZ), which adheres the flagellum to the cell surface.

283 g piece essential for linking the developing flagellum to the head during late spermiogenesis.

284 n mode is triggered by an instability of the flagellum under reversal of the rotation and the applied

285 rs, but she also posited that the eukaryotic flagellum (undulipodium in her usage) and mitotic appara

286 The assembly of a flagellum uses a significant proportion of the biosynthe

287 The FP neck is tightly associated with the flagellum via a series of cytoskeletal structures that i

288 In the mutants, formation of the flagellum was inhibited at its earliest stage.

289 To measure cAMP dynamics in the sperm flagellum, we generated transgenic mice and reveal that

290 cell membrane around the proximal end of the flagellum, which is an important organelle for endo/exoc

291 surface via a large bulge at the base of the flagellum, which is then remodeled into a thin attachmen

292 the stability of an inner-arm dynein in the flagellum, which may be shared by all the centrin-contai

293 T. brucei has a single flagellum whose base contains a bulblike invagination of

294 t creates the pore through which the growing flagellum will elongate from the cell body.

295 This bacterium possesses a single flagellum with one rotor and two sets of stators, only o

296 agellin subunits that make up the Salmonella flagellum, with which YSD1_29 engages to initiate infect

297 uiring digital isolation and location of the flagellum within a sequence of frames.

298 ealed that KH1 is located at the base of the flagellum, within the flagellar pocket, where it associa

299 centrations kinetically compartmentalize the flagellum: Within milliseconds, cGMP is relayed from the

300 o ensure smooth and fast transport along the flagellum without standing in each other's way.