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1 ERF96 participates in DNA interaction in the flanking region.
2 ce of CGC motifs in Box D and its downstream flanking region.
3 mutants with T-DNA insertions in the FLDH 5' flanking region.
4 05 (M67V) in exon 3 and rs11579627 in the 3' flanking region.
5 an BORIS expression, we characterized its 5'-flanking region.
6 plicing variants while characterizing its 5'-flanking region.
7 factors (e.g. AP-1 and NF-kappaB) to its 5'-flanking region.
8 gment contains the small fragment and the 5'-flanking region.
9 smids containing fragments of the SULT1C3 5'-flanking region.
10 e, we aimed to clone and characterize its 5'-flanking region.
11 on-canonical E box sequence CACGCG in the 5'-flanking region.
12 nctional allele to a 100-bp window in the 5'-flanking region.
13 have significantly lower density compared to flanking regions.
14 sequences, e.g. promoter, telomeric and gene flanking regions.
15 to recognize different DNA sequences in the flanking regions.
16 incidence of cryptic repetitive DNA in their flanking regions.
17 nd mature miRNAs are lower than the adjacent flanking regions.
18 eported SNPs at r2 > 0.8 across RETN and its flanking regions.
19 NA substrate with subsequent ligation of the flanking regions.
20 controlled by at least three separable gene-flanking regions.
21 l-length human MYOCILIN (MYOC) gene and long flanking regions.
22 sin, may form a less stable coiled-coil than flanking regions.
23 aining the human GNLY gene and its 5' and 3' flanking regions.
24 s and CO rates were slightly elevated in the flanking regions.
25 leavage sites engineered into signal peptide flanking regions.
26 motifs with highly diverged "non-alignable" flanking regions.
27 known sequence region to its uncharacterized flanking regions.
28 ing the full-length mouse Myoc gene and long flanking regions.
29 C-rich regions and that NRF1 prefers AT-rich flanking regions.
30 ias precisely at the border between CNEs and flanking regions.
31 ar between the recombination-free region and flanking regions.
32 version with partially similar but unrelated flanking regions.
33 ing from both within the G4 motifs and their flanking regions.
34 et cleavage by AGO3 requires both 5'- and 3'-flanking regions.
35 le nucleotide polymorphism (SNP) panels from flanking regions.
36 babilities of folding for different sizes of flanking regions.
37 igh read coverage over the targets and their flanking regions.
38 ll as the bending and twisting rigidities of flanking regions.
39 ocus sequencing resources on genes and their flanking regions.
40 signals that distinguish peak sequences from flanking regions.
41 ferent conservation levels relative to their flanking regions.
42 tural accessibility of the binding sites and flanking regions.
43 otein expression via the MLL CXXC domain and flanking regions.
44 pri-mir-16 variants bearing single-stranded flanking regions.
45 include 70-nucleotide hairpins with unpaired flanking regions.
46 resequence NPR3 exons, splice junctions, and flanking regions.
47 ss dense spacing (one SNP per 50 kb) for the flanking regions (117.7-126.6 and 160.2-167.5 MB) and ge
48 ficial chromosome containing 68 kb of the 5'-flanking region, 45 kb of the coding sequence, and 53 kb
50 not identified at either the 5' and 3' HMGCR flanking regions (+/-5000 bps) or at negative control ge
51 in rat corticostriatal brain slices, either flanking region alone sufficed to generate a neurotoxic
54 ach allows to rapidly identify the transgene flanking region and can easily be implemented by the enf
55 icity to DNA junctions possessing a 5'-ssDNA flanking region and can initiate translocation from this
56 unctional C/EBP binding site in the Gfi-1 5'-flanking region and enhances the promoter activity of Gf
57 Expression of the antisense variable region/flanking region and the S-region transcripts were found
59 ssion of reporter gene constructs for the 5'-flanking region and the variable number of tandem repeat
62 c clones, containing the complete locus plus flanking regions and permit seamless insertion of the re
63 "beta-hairpin" are needed to melt the origin-flanking regions and that the T-ag helicase domain selec
64 proven by the characterization of transgene flanking regions and the combinations of elements that a
65 ying this approach to 17 microRNAs and their flanking regions and with a reporter for miR-142 activit
66 en systematically reduced the size of the 5' flanking region, and determined that the nt-339 to nt-39
67 f DNase I hypersensitive sites within the 5' flanking region, and identified a candidate Igh regulato
68 3' ends, it was detected within genes and 3'-flanking regions, and Cdk7 inhibition delayed pausing an
69 e generally hypomethylated relative to their flanking regions, and the binding of some transcription
71 howed that the Ser74-Gly75 dipeptide and its flanking regions are highly conserved among a wide range
75 ious work identified the E2F1 marked box and flanking region as critical for the specificity in E2F1
76 CG repeats along with varying extents of DNA flanking regions as well as very small mutations includi
77 l causal variants are enriched in coding and flanking regions, as well as in regulatory elements, and
78 binding site accessibility, as determined by flanking region AU content, could fully explain the disc
80 deletions encompassing the NF1 gene and its flanking regions belong to the group of genomic disorder
81 ns of SLF genes, resulting in highly similar flanking regions between different types of SLF and betw
85 hat changes in the C-terminus of the peptide-flanking region can substantially alter T-cell receptor
86 human triplet repeats and their surrounding flanking regions can be used to produce a cost-effective
89 minal turn-helix-turn motif and a C-terminal flanking region containing an amphipathic Jalpha helix.
91 ion of ZmBCH2, we isolated 2036 bp of the 5'-flanking region containing the 263 bp 5'-untranslated re
92 tional regulation of the psiBCH gene, its 5'-flanking region containing the putative promoter was fus
93 ealed that the proximal 1.4 kb of the 5'-end-flanking regions containing several consensus motifs was
96 he high degree of sequence similarity in the flanking regions could often be explained by the presenc
97 of the extended smooth muscle alpha-actin 5'-flanking region demonstrated that assembly of the nucleo
102 reening for polymorphism and ensure that the flanking regions do not have length difference that woul
103 cessibility increase and spread to genic and flanking regions due to destabilization of the histone d
105 ne lactoferrin gene, containing 4.4 kb of 5' flanking region, exon 1, intron 1, and exon 2, was isola
106 otated the human gene and resequenced its 5'-flanking region, exons, and splice junctions using 60 DN
107 ) promoter transcriptionally regulated by 5' flanking region extending 16 kb upstream that contains c
111 CR1 retrotranspositions were used to examine flanking regions for GC content and nucleotide bias at t
112 CpG dinucleotides located within binding or flanking regions for the transcriptional regulator CCCTC
113 3RSS that reduces the distance between these flanking regions from >160 A in the linear substrate to
114 aracterized, together with an additional 270 flanking regions from one side alone, from a diverse col
117 s reporter gene demonstrated that the E1A 5'-flanking region had promoter activity, which contains mu
119 ns are enriched for long DNA repeats and the flanking regions have high alignment scores, suggesting
121 , CRMs are significantly more conserved than flanking regions, hence, bearing the signatures for puri
122 all proteins containing the TM and a limited flanking region homologous to the fusion protein of the
123 ion of cDNA ends) analyses of the 5' genomic flanking region identified eight conserved HuD leader ex
124 ISs, we aligned transposase genes and their flanking regions; identified the ISs' possible terminal
127 xamined sequences of the Pi-ta locus and its flanking regions in 159 accessions composed of seven AA
128 compared with other guanine residues of the flanking regions in both in vitro and in vivo footprinti
132 ment of TFs and cofactors in gene bodies and flanking regions in gene lists without an a priori binar
133 g of variants across TNF/LTA genes and their flanking regions in the Gambian and allied populations m
134 PL35a and RPL23, and ferredoxin, FDX1, whose flanking regions including promoters, terminators and un
135 er constructs containing deletions in the 5' flanking region, including a 94 bp promoter that lacks a
136 rized a 4868bp fragment of the human MAPT 5'-flanking region, including the core promoter region (-30
137 ed that Elf3 amino acid residues within this flanking region, including Trp361, are important for the
138 from plasmids with the observed noncanonical flanking regions, indicating that piggyBac could generat
139 ng sequential 5'deletion constructs of the 5'flanking region into NIH/3T3, M12.4, and RAW264.7 cells.
142 ration of the conserved elements in ITS2 and flanking regions, it appears that there are three major
144 e, a distinct substitution in the N-terminal flanking region located 5 residues upstream of the epito
145 tochondrial genomes with a variation in gene flanking regions make S. vulgaris an excellent model for
148 he full-length Hztransib inserts into the 5'-flanking region of a xenobiotic-metabolizing P450 gene C
149 an increase of H3K4me2 and H3K4me3 in the 5' flanking region of an active var locus and expand on an
150 that modification of the C-terminal peptide-flanking region of an influenza hemagglutinin (HA(305-32
152 on between PBC and rs231725, a SNP in the 3' flanking region of CTLA4 located outside of the area pre
155 nked SNPs (rs6493497 and rs7176005 in the 5'-flanking region of CYP19 exon 1.1) that were significant
156 ut cell line, it does not insert into the 5'-flanking region of CYP6B8 in the laboratory strain.
157 e sequence containing C-6530>G SNP in the 5' flanking region of ERCC6 from Sp1 on the C allele to SP1
159 All exons, splice junctions, and the 5'-flanking region of GSTP1 were resequenced using 60 DNA s
161 this STAT5-binding site-containing distal 5'-flanking region of IGF-I gene may be an enhancer mediati
163 and rs6835457 located in the 3'-untranslated flanking region of IL21 (odds ratio 1.11 [95% confidence
164 regulatory enhancer element found in the 5' flanking region of many phase II detoxification enzymes.
165 micro-RNA target sequence in the downstream flanking region of MC4R as a strong, probable functional
166 s using deletion constructs of a proximal 5'-flanking region of miR-98 did not reveal a hypoxia-respo
169 33 base pairs of upstream sequence of the 5'-flanking region of mVGLUT2 complementary DNA was cloned.
170 response to 7-ketocholesterol within the 5'-flanking region of profilin-1 was dependent on a single
176 tructural association between the N-terminal flanking region of the A1 domain (amino acids Gln(1238)-
177 ence, Gln(1238)-Glu(1260), in the N-terminal flanking region of the A1 domain, together with the asso
178 A detailed analysis of the 14-kb long 5'-flanking region of the ACT gene indicated the presence o
182 ns, the promoter region, and 60 bp of the 3' flanking region of the canine FGFR3 gene were sequenced
183 trol chicken EF-2 gene transcription, the 5'-flanking region of the chicken EF-2 promoter was analyze
185 defined nucleotide sequence in the distal 3' flanking region of the CP27 proximal promoter CCAAT box.
188 e determined that another CpG site in the 5'-flanking region of the Fgf-1.A isoform was also methylat
192 putative NFI and AP-1 elements within the 5'-flanking region of the GFAP gene also diminished basal e
193 of the coding sequence, and 53 kb of the 3'-flanking region of the hAT1R gene was employed to genera
195 naturally occurring polymorphisms in the 5' flanking region of the human angiotensinogen (AGT) gene,
196 ing to the NF-kappaB motif present in the 5' flanking region of the human IFN-gammaR2 promoter that w
198 We recently demonstrated that the 3-kb 5'-flanking region of the human ROBO4 gene directs endothel
201 e beta cell, areas of identity within the 5' flanking region of the mouse, human, and rat mafA genes
203 nstructs driven by the approximately 5 kb 5'-flanking region of the murine SerpinB2 gene and several
204 esponse element (CRE)-like element in the 5'-flanking region of the MuSK gene binds to CREB1 (CRE-bin
205 results indicate that a variation in the 5' flanking region of the myostatin gene is associated with
206 Loss of repressive activity within the 5' flanking region of the NK1 partly accounts for constitut
207 ors containing different fragments of the 5'-flanking region of the Pde3b gene, we identified a dista
209 e Sp3 promoter, we isolated 2.1 kb of the 5'-flanking region of the Sp3 gene, which contains Sp1/Sp3
213 the previously published signature in the 5' flanking region of the tpp15 gene, can differentiate the
216 pping we interrogated SNPs within +/- 250 kb flanking regions of 14 previously reported index SNPs fr
217 . populations, by resequencing the exons and flanking regions of 3,873 genes in 154 chromosomes from
219 V genomes were significantly enriched in the flanking regions of 84.5% the integration sites, with a
220 Hippocampal cis-meQTL-CpGs are enriched in flanking regions of active promoters, CpG island shores,
222 in the sequences with low CpG density in the flanking regions of Alu repeats, rather than within the
224 orms of OI, we sequenced the coding and exon-flanking regions of COL1A1 and COL1A2 in a cohort of 63
225 lymorphisms (SNPs) located in the coding and flanking regions of ENPP1 were genotyped in 577 African-
227 actors have putative binding sites in the 5'-flanking regions of genes coding for the channel protein
230 EC2 specifically binds RY motifs from the 5' flanking regions of LEC2-induced genes provides strong e
231 in and displacement of the N- and C-terminal flanking regions of LOV2 (404-546), both of which consti
237 Statistical machine learning revealed that flanking regions of putative DIMM binding sites contribu
239 searched for ChoRE-like sequences in the 5'-flanking regions of several genes that responded rapidly
240 s revealed potential genetic exchange in the flanking regions of SLF genes, resulting in highly simil
241 ng cis-acting regulatory sequences in the 5' flanking regions of Snai1 and Wnt4, thereby inhibiting d
243 intly estimating dates of recombination from flanking regions of the breakpoint and further illustrat
244 ein binding sites and CpG islands within the flanking regions of the circular RNA back-spliced juncti
245 ng the physical interaction of the 5' and 3' flanking regions of the FLC locus using chromosome confo
247 ining all the introns, exons, and 5'- and 3'-flanking regions of the hCYP11B2 gene containing either
248 into consideration the weak signals from the flanking regions of the motifs; and (iv) analyze co-occu
249 p to 1 kb past the poly(A) sites into the 3' flanking regions of the nematode genes before it termina
250 tion indicating that charged residues in the flanking regions of the peptide are not the major determ
252 ds to increase with the genome size; (c) the flanking regions of the recently active IS elements are
253 the C-terminal alpha-helix and two immediate flanking regions of the S-loop of the SDH molecule.
254 GC content in conversion tracts compared to flanking regions of the same genes nor in conversion tra
256 scovered elements are likely to exist in the flanking regions of this and other functional RNAs, and
258 xamining the evolutionary properties of gene-flanking regions on the X Chromosome, we find evidence t
259 enhancer cluster or parts thereof, Nppb and flanking regions or the entire genomic block spanning Np
260 earch for a genetic modifier within POLG and flanking regions potentially involved in the regulation
262 A central question is whether and how these flanking regions regulate ATP hydrolysis or the coupling
264 duplication CNVs into their transcribed and flanking regions, respectively, supporting a role for tr
267 hese maturation RNAs all possess in their 5' flanking regions RY motifs, DNA elements bound by other
268 at topologically associating domain boundary-flanking regions showing high interaction frequencies wi
269 in class II epitopes was not different from flanking regions, so CD4 T cells rarely exert selection
271 ands and 5' CAGE tags mapped in the upstream flanking region surrounding the precursor miRNA (pre-miR
272 ed 3' and/or 5' single-stranded (ss)-(dT)(n) flanking regions (tails) (n ranging from zero to 20 nt)
273 consists of 11 tandem HAT repeats and short flanking regions that are also predicted to form helical
274 in vivo to the pre-rRNA and to U3 sequences flanking regions that base-pair to the pre-rRNA includin
276 single HMG box, as well as basic and acidic flanking regions that vary greatly in length and charge.
277 putative regulatory sequence in the ULK1 5'-flanking region, the mutation of which increased ULK1 pr
278 al region was reversed with respect to these flanking regions, the origin was still able to replicate
280 were collapsed across CpG islands and their flanking regions to identify variants collectively assoc
281 eously to identify genes, predicted promoter flanking regions, transcription factors and CTCF binding
282 Bioinformatic analyses of the human RPGR 5'-flanking region uncovered potential transcription factor
284 ells through transcription control in the 5'-flanking region upstream from the Pax6 P0 promoter.
286 enes drop away quite rapidly in the external flanking regions (upstream of the 5' paralog and downstr
289 rter construct containing 120 kb of RANKL 5'-flanking region was stimulated by dibutyryl-cAMP in stro
290 In silico PCR analysis based on conserved flanking regions was also used to interrogate hotspots i
293 entire Ctcf-bounded Wnt4 locus, but not the flanking regions; we term this mode of action "chromatin
294 elongation early in transcription, and in 3' flanking regions where termination is enhanced by TFIIS(
295 reveals that it also has enhancers in the 3' flanking region which contain RAREs and have the potenti
296 ce revealed the putative lpm cluster and its flanking regions which harbor 43 open reading frames.
297 we present the first survey of promoter (5'-flanking) regions, which are rich in cis-regulatory sequ
299 bp duplex with a 3'-(dT(20)) single-stranded flanking region, with apparent affinity in the micromola
300 y proteins that bind the E2F1 marked box and flanking regions, with a potential role in E2F1 apoptosi