ライフサイエンスコーパス: flaw

1 were excluded from review for an identified flaw.

2 ue to reliance on a single primer with known flaws.

3 es are limited by significant methodological flaws.

4 ause of their brittleness and sensitivity to flaws.

5 nd management of chest pain (CP) has several flaws.

6 sensitivity with respect to cracks and other flaws.

7 completeness, or simply because of avoidable flaws.

8 whereas SHIP1 inhibition worsened migratory flaws.

9 but the study was limited by methodological flaws.

10 tical phylogenetic tests plagued by profound flaws.

11 We propose changes to address these flaws.

12 and often demonstrate extreme sensitivity to flaws.

13 ethod comparison due to a number of inherent flaws.

14 ves all of these studies have methodological flaws.

15 fety seat legislation and had methodological flaws.

16 esults are inflated by recall bias and other flaws.

17 he material is dense and free of geometrical flaws.

18 ffered evidence for this hypothesis has many flaws.

19 l interactions or the result of experimental flaws.

20 esting that they may share common structural flaws.

21 ed to be a potential cause of lack-of-fusion flaws.

22 l hernia and to evaluate their strengths and flaws.

23 patients is further limited by methodologic flaws.

24 e sample-size scaling of the distribution of flaws.

25 that mechanisms for tolerance to insulin are flawed.

26 hypothetical deployment scenarios) would be flawed.

27 rticles, we show that this assumption may be flawed.

28 an, however, that the current procedures are flawed.

29 size fits all" paradigm for drug delivery is flawed.

30 te their apparent merit, these arguments are flawed.

31 f agents to use in adjuvant trials is deeply flawed.

32 ding of this type of anomalous motion may be flawed.

33 dwich configuration of the benzene dimer are flawed.

34 to assess whether the original analyses were flawed.

35 pt, relating to the shape of sample SADs, is flawed.

36 irective concept itself may be fundamentally flawed.

37 logy of fluctuating asymmetry studies may be flawed.

38 al level analysis or director opinion may be flawed.

39 dology used to develop these models is often flawed.

40 past GeneChip analyses may be significantly flawed.

41 t or (2) measurements of sugar transport are flawed.

42 the internal initiation hypothesis is often flawed.

43 ich the data analysis and interpretation are flawed.

44 obesity, may be insufficient and potentially flawed.

45 studies have been small and methodologically flawed.

46 For some GLs, the "Scientific rigor" domain flawed.

47 ers cited to point out their merits or their flaws?

48 he 'epidemiological studies are sufficiently flawed'; (2) 'the biological evidence is of moderate str

49 nferred by statistically and chronologically flawed age-depth interpolations, and in several the ages

50 rmality in behavioral force-matching and the flawed agency judgments characteristic of positive sympt

51 agome geometry that contained pre-fabricated flaws always failed at the same load as the pristine spe

52 sed conferences and risk assessment studies, flawed analyses (including a recent tome from the OECD),

53 o being, how it is calculated, and how it is flawed and contributing to decreasing physician payments

54 d in academic settings, and methodologically flawed and did not measure clinically meaningful outcome

55 was that the SP evidence base was seriously flawed and did not warrant the introduction of SP.

56 ultiplicative rating scale of the MacDQoL is flawed and does not provide scientific measurement of VR

57 Some have claimed that this UL is flawed and has become an obstacle to the wider adoption

58 off-the-shelf technologies are fundamentally flawed and inaccurate for the operating conditions descr

59 reliance on metrics that are mathematically flawed and insufficiently diverse to account for the var

60 suggest that this estimate is statistically flawed and misleading and says nothing about the impacts

61 g of such processes are established based on flawed and non-representative models.

62 n that show an effect on cardiac disease are flawed and offer no insight into normal human physiology

63 data matrices indicate that this approach is flawed and should be avoided, and that within the marine

64 Methods of lethal injection anaesthesia are flawed and some inmates might experience awareness and s

65 y grizzly bears post-wolf reintroduction are flawed and tenuous at best.

66 hemical investigations have been technically flawed and that NAA may not be associated with brain ene

67 ysis of Australopithecus sediba mandibles is flawed and that specimen LD 350-1 cannot be distinguishe

68 on 1033 SME, we show that the 2014 data are flawed and that the more recent data provide no evidence

69 ts have been discredited, the methodology is flawed and the causal inference drawn from the results p

70 ve led to the claim that this explanation is flawed and therefore that Fisher's hypothesis can and sh

71 in septic patients, the experimental design flaws and biases of recent low-dose (physiologic) steroi

72 and interpretation are sometimes subject to flaws and errors.

73 donation, the Iranian Model now has serious flaws and is potentially inhibiting substantial growth i

74 linical development, including due to design flaws and reporting bias.

75 g by shear-band sliding in the presence of a flaw, and thus exhibit toughness-strength relationships

76 s as merely non-specific rigid inclusions is flawed, and each protein has a unique mechanical signatu

77 valuating CAM therapies are methodologically flawed, and often times there are inconsistencies across

78 266-269, ) suggests that these studies are flawed, and posits that such methodologies cannot be use

79 ssume a definitive prognosis--are clinically flawed, and procedural barriers may further limit their

80 se if the methods used to conduct the SR are flawed, and reporting of the SR is incomplete.

81 gest that older detection methodologies were flawed, and the limitations of these methods could accou

82 onstrating the validity of this assertion is flawed, and the residual intrinsic variability so define

83 show that this "contradiction" is based on a flawed approach to calculating the wavelength in models.

84 hat sexual selection theory is fundamentally flawed are simply wrong and ignore an enormous body of e

85 No flaws are observed within the frustule material down to

86 Lower barriers to publication of flawed articles are seen in the increase in number and p

87 articles or an increase in the rate at which flawed articles are withdrawn.

88 Retraction of flawed articles is an important mechanism for correction

89 this reflects an increase in publication of flawed articles or an increase in the rate at which flaw

90 wever, we contend that their conclusions are flawed as the result of a number of failings of both the

91 initial cell cluster size, and are therefore flawed as universal measures of plasmid transfer efficie

92 We show here that this is a flawed assumption because regional climates have changed

93 ed brainstem structures in birds is based on flawed assumptions of homology to mammals.

94 standing of the importance that pre-existing flaws at the intaglio surface have on fatigue failures.

95 and other environmental factors, providing a flawed basis for beach closure decisions.

96 The epidemiological studies were considered flawed because it was not possible to distinguish reliab

97 e (mocap) technology and the spectrograph is flawed because only vocal articulators are hidden.

98 However, many existing approaches are flawed because the assumptions of what cause excessive l

99 However, this approach is flawed because the density of T-tubules as well as non-T

100 archetypal natural kind-may be fundamentally flawed because the very concept of "the gene" as a discr

101 obal biogeochemical cycling, are potentially flawed because they do not consider this land use in the

102 alternative cover stories are fundamentally flawed because they introduce new forms of demand.

103 f effect cannot be attributed to a technical flaw, because identical doses of zVAD were able to rescu

104 ual progression of "isolating mechanisms" is flawed, because intra-group random mating is assumed.

105 Pak2 leads to early embryo lethality due to flawed blood vessel formation in the embryo body and yol

106 rchers as attested to by the substantial, if flawed body of literature on the topic.

107 the modeling with VcINDY as the template is flawed, but this is the best available option at this ti

108 Both are flawed by distorting the structure of the symmetric junc

109 the ITT analysis for all lesions, which was flawed by major protocol deviations in 8.5% of the patie

110 t, compared to a 3D observation, 2D data are flawed by over-reporting and under-reporting of locomoto

111 However, this is considerably flawed by the accumulation of contaminant PEG inside the

112 Opioid guidelines are inherently flawed by the anchoring heuristic and efforts should cen

113 Both of these studies, however, were flawed by the lack of suitable controls for assessing vi

114 Preclinical studies have been flawed by use of models of transient not permanent brain

115 f proteins and detect backbone or side-chain flaws by taking into account an ensemble average of chem

116 ing US biomedical research from its systemic flaws" by Alberts and colleagues in the Proceedings of t

117 rge sequences and corrects a number of minor flaws causing misreporting of hits in exceptional cases.

118 avioral sciences in helping detect and avoid flawed choice.

119 nse of other cognitive processes, leading to flawed circular arguments.

120 We conclude that, despite its flaws, CLARITY provides important insight and, taken tog

121 en due to inadequate preclinical testing and flawed clinical development programs.

122 nd the dual-reporter method may thus produce flawed conclusions about the properties of the system, p

123 d observation processes, which might lead to flawed conclusions.

124 ntervention and control groups, major design flaws, contradiction by subsequent larger higher quality

125 Instead of the usual, conceptually flawed control, we used a series of novel transfer tasks

126 previous studies, in which methodologically flawed cue-target tasks were used.

127 science and overinterpreting preliminary or flawed data.

128 can stable multitasking emerge despite this flawed decision-making?

129 e horizons), and definition of outcomes (eg, flawed definition and grouping together of adverse effec

130 Estimates of material surface flaw distributions and fatigue parameters for 3 reinforc

131 icates that methods associated with PISO are flawed due to non-synchronization of lattice temperature

132 Unfortunately, many of these studies are flawed, either through questionable experimental design

133 insensitivity of failure to the presence of flaws even when made entirely of intrinsically brittle m

134 ence-based knowledge suggest that systematic flaws exist in the production of scientific evidence, in

135 nularity and coding inaccuracies may lead to flawed findings.

136 s low as reasonably achievable), are fatally flawed, focusing only on molecular damage while ignoring

137 ation, but these data are disproportionately flawed for AIAN because of racial misclassification.

138 ties that provide a crack-arrest barrier for flaws formed in the brittle enamel1.

139 lysis are increasingly cited as conceptually flawed, given the extreme variation within traditionally

140 ion in a way that is not dependent on either flawed gold standards or the input data itself.

141 Methodological flaws have been indicated as a possible explanation for

142 rs intrinsically inefficient, and scientific flaws have been noted by many authors.

143 epair is not unique to MRL-Fas(lpr) mice, as flawed healing is a feature of other lupus-susceptible m

144 included in this review have methodological flaws however.

145 These studies are flawed if the DNA is isolated from misidentified modern

146 science, research experiences may reinforce flawed images especially of research practices and conce

147 A critical flaw in Branigan & Pickering's (B&P's) advocacy of struc

148 n perception and judgment is therefore not a flaw in investigating top-down effects of cognition on p

149 which has long been considered as a critical flaw in lithium-sulfur batteries.

150 in membrane proteins, overcoming a critical flaw in previous membrane models that were prone to gene

151 We address a conceptual flaw in the backward-time approach to population genetic

152 We have analyzed a systematic flaw in the current system of gene identification: the o

153 y tri-n-butylstannane (SnH) reveal a serious flaw in the current view of the kinetic radical chain: t

154 Finally, we report a flaw in the Egfr-null mosaic Minute+ clone approach.

155 Due to a flaw in the International Classification of Diseases, Ni

156 s Letter, and new information has revealed a flaw in the interpretation of Fig.

157 s Letter, and new information has revealed a flaw in the interpretation of Fig. 2h.

158 Here, we attribute this contradiction to a flaw in the validation methods, which ignore spatial aut

159 Our data suggest that PLE patients have a flaw in their immunoregulatory response to ultraviolet-r

160 ard et al. (2014) identifies an experimental flaw in these previous studies suggesting that astrocyte

161 A critical flaw in this picture has long been that the reported lip

162 oblems in other strains of mice suggesting a flaw in this theory.

163 ngiogenesis in skeletal muscle is profoundly flawed in both structure and function, with no evidence

164 g of this mystery, but is the mystery itself flawed in its assumptions?

165 ith all experimental animal models, they are flawed in one way or another by virtue of the means by w

166 e, which have been shown to be significantly flawed in recent investigations.

167 ival from earlier initiation of dialysis are flawed in that they have measured survival from start of

168 vement in understanding (all P<.05) but were flawed in that they may have mistaken rote memorization

169 ations of social psychology as fundamentally flawed in understanding stereotype accuracy and the effe

170 ata exist to confirm their safety because of flaws in 1976 TSCA.

171 ies, ranging from disease-specific intrinsic flaws in blood supply, angiogenesis, and matrix turnover

172 We then highlight systemic flaws in contemporary conservation and identify opportun

173 However, flaws in design and implementation invalidate this chall

174 The review revealed major methodologic flaws in design, reporting and results of the studies, i

175 to frequent reliance on claims data with its flaws in determining quality, fragmentation of measureme

176 ly determined but recent data indicates that flaws in innate immune responses, involving the interfer

177 Design flaws in longitudinal database studies are avoidable but

178 by piezoelectric crystals was used to detect flaws in metals.

179 y, our work documents significant tabulation flaws in one of the most cited and active online scienti

180 ion are discussed, which highlight the major flaws in parametrization of existing models.

181 However, flaws in patient identification challenge the utility of

182 Commonly identified flaws in RCTs were as follows: insufficient data provide

183 od either reaches atomic accuracy or exposes flaws in Rosetta's all-atom energy function, indicating

184 on system, and points to potentially serious flaws in simplified mathematical relationships often use

185 In addition, we use these results to expose flaws in some of Michael Behe's arguments concerning mat

186 Particular attention is paid to flaws in some of the published models, and suggestions a

187 s, but some of those studies were plagued by flaws in study design or analysis.

188 In research, lack of coordinated effort, flaws in study design, changes in simulator-validation c

189 from consideration unless there were serious flaws in study design.

190 There are 2 inherent flaws in such an approach.

191 strategy for identifying unpredicted design flaws in synthetic genomes and for elucidating rules gov

192 These two findings highlight the serious flaws in the assumptions of the conventional mobile-immo

193 We discuss fundamental flaws in the CP, including the lack of consistency of vi

194 However, we find serious flaws in the data, methods, and interpretations of this

195 Many flaws in the design and interpretation of new experiment

196 rd work is required to prepare reagents, but flaws in the design of many binding experiments limit th

197 mplex interventions in health care research, flaws in the development process immediately impact the

198 ttributing the differences to methodological flaws in the earlier article.

199 l composition, can be directly attributed to flaws in the force field's ability to properly account f

200 ifferent statistical methods, or fundamental flaws in the hypothesized association between hospital-w

201 Here, I argue that emerging flaws in the integrity of the peer review system are lar

202 er, lineage-tracing studies have highlighted flaws in the interpretation of former studies, revealing

203 In our view, there are numerous flaws in the investigation that cast doubt on this messa

204 so many HIV patients has led to fundamental flaws in the management of advanced HIV infection.

205 ese guidelines are based reveals significant flaws in the methodology and conduct of the relevant met

206 Although flaws in the methodology have been acknowledged, one gro

207 We identified substantial flaws in the original and updated GFT models at all thre

208 After revealing flaws in the psychological approach, we introduce a psyc

209 This paper will outline some of the flaws in the studies thus far, and problems for the futu

210 rch-can go a long way to remedying remaining flaws in the system.

211 t al.'s central argument, there are numerous flaws in the way people use causal models.

212 some important conceptual and methodological flaws in their argument, we report the results of a seri

213 s in computers and other electronic devices, flaws in their properties mean that intensive research i

214 y is a new, unifying synthesis that draws on flaws in three leading theories of ageing.

215 We review the flaws in Williams' model, explore alternative explanatio

216 ental sequence of human language learning is flawed: in fact, infants already know the meanings of se

217 ryos and fetuses) to pervasive architectural flaws (including pseudogenes, parasitic mobile elements,

218 Methodological flaws, including survival bias, and heterogeneity betwee

219 of its inclusion as a diagnosis, and logical flaws inherent in the various definitions are discussed

220 However, this flaw is less relevant as a source of bias in direct comp

221 This flaw is termed lead-time bias.

222 hese have well understood caveats; a notable flaw is the ad-hoc treatment of multi-loops, also called

223 recognized that the method has a fundamental flaw: It works poorly on networks that contain short loo

224 Duodenoscope design flaws leading to transmission of multidrug-resistant org

225 Concern over the impact of flawed measurement continues to nag epidemiology.

226 ngs PrEP roll-out has lagged, in part due to flawed messaging.

227 pment of cardiometabolic disease is based on flawed methods for comparing different age periods.

228 or later cardiometabolic disease is based on flawed methods for comparing different age periods.

229 Many previous analyses have used flawed metrics to evaluate herbicide intensity and toxic

230 The test, however, is based on a flawed model of causality, and the ecological groups are

231 o produce a valid topology from an otherwise flawed model.

232 uctural valve deterioration (SVD) is a major flaw of bioprostheses.

233 Burnt tuna (BT), or yake-niku, is a quality flaw of the muscle characterised by a pale colour and gr

234 Strategies to ameliorate the flaws of current chemotherapeutic agents, while maintain

235 the field can be attributed to the inherent flaws of layer-by-layer printing and, in particular, ani

236 Emerging evidence suggests that design flaws of randomized controlled trials can result in over

237 data in delineating truths and illuminating flaws of retrospective data on a controversial topic.

238 ime of colonoscopy may aid in overcoming the flaws of surveillance.

239 ulated mechanical defects, and manufacturing flaws of the device.

240 We first describe the flaws of the traditional (chi-squared) tests for both al

241 echnological considerations and the inherent flaws of these methods, which may have an impact on the

242 he glomeruli, it represents a feature, not a flaw, of the olfactory bulb.

243 takes into consideration prevalent security flaws on these routers.

244 Finally, defects and flaws on TiO2 film were easily recognized via surface pr

245 chemical shifts for approximately 94% of the flaws, on average, without introducing a significantly l

246 We reject those notions as either logically flawed or at best insufficient in the absence of natural

247 when the available transcript annotation is flawed or incomplete.

248 Their analysis is fundamentally flawed, owing to the use of model ensembles with too few

249 Our findings challenge the existing flawed paradigm of maximum dose treatment, a strategy th

250 is by another Y-family DNA polymerase and/or flawed participation of an accessory protein is a more l

251 ing respiratory mucosal sampling methods are flawed, particularly in a pediatric bronchiolitis settin

252 umerous phase II studies and underpowered or flawed phase III studies.

253 This flawed process results in billions of dollars worth of v

254 nd continues to be misinterpreted, producing flawed projections and misdirected health goals.

255 This aberrant UVB response represents flawed protection from UVB damage potentially resulting

256 vement created and perpetuates the seriously flawed protocol of lethal injection.

257 uilibrium for PAHs and SOA are fundamentally flawed, providing an explanation for the persistent disc

258 be necessary to avoid false conclusions from flawed Q-PCR assays for which sequence variation among i

259 40 years that these inferences are based on flawed reasoning and obscured by model mimicry.

260 ental designs, inappropriate analyses and/or flawed reasoning.

261 ributions, originates in the assumption of a flawed reference state for energy decomposition analyses

262 This setup has significant flaws related to metal/salt reference electrodes: they a

263 owever, normative databases can sometimes be flawed relative to atypical ONH or RNFL morphologies and

264 t or a 2-way ANOVA, in these situations give flawed results and should not be used.

265 ntially drive false associations and lead to flawed results.

266 hough perhaps well-intentioned, was based on flawed scientific interpretation of trial results that c

267 ), fails to form in this agglomerate causing flawed segmentation.

268 the accompanying plasticity helps to reduce flaw sensitivity in the glass, thereby promoting structu

269 dy to CA19.9 (a highly visible but partially flawed serum biomarker for several cancers) was radiolab

270 laparoscopy is mostly from the research with flawed study designs.

271 Peer review is often criticized for being flawed, subjective and biased, but research into peer re

272 tation of this phenomenon in the article was flawed, subsequent simulations show that the effect comp

273 produce multiple missing values (MVs) due to flaws such as dust, scratches, insufficient resolution o

274 city' are poorly defined terms that serve as flawed surrogates for multiple environmental and genetic

275 blems, such as lack of access, inequity, and flawed system designs.

276 pothesis that RCTs have fewer methodological flaws than non-RCTs, limitations of 17,591 RCTs and 39,0

277 only used amino acid encoding method has the flaw that leads to large computational cost and recognit

278 In this article, we describe flaws that affected that study's conclusions and present

279 However, several key methodological flaws that are hindering progress in the study of insect

280 We identified two flaws that call into question the findings and their rel

281 vational studies, they might be explained by flaws that can be avoided by explicitly emulating a targ

282 Critical examination of the evidence reveals flaws that leave room for alternative interpretations, s

283 A few trials had poor accrual or had design flaws that led to conflicting results.

284 Although not without flaws, the model provides an explanation for why primary

285 We also show that, while flawed, this data set is still a useful tool for method

286 ent in toughness and strength with very high flaw tolerance of zirconia/Ta composites.

287 This localization offers flaw tolerance, allowing ductility to win over fracture.

288 toughening strategy in nacre's hierarchical flaw-tolerance design.

289 , has already been used to shed light on our flawed understanding of natural levels of Pb in Earth's

290 s on decoding 'parts', and often relies on a flawed 'veridicality' assumption.

291 n, we show how community state-clustering is flawed when it comes to characterizing within-host dynam

292 Conventional systems are potentially flawed when PY is used as the control signal because the

293 But, this technique becomes fundamentally flawed when there are unaccounted sources of variability

294 ically that it can introduce a more sinister flaw: when there is complete linkage between loci affect

295 ods used for model development are generally flawed which reduces the potential for using these model

296 edian cracks in samples with no pre-existing flaws, while indenters with larger indenter angles canno

297 A critical flaw with detergent approaches is the removal of the pro

298 hthalmology has determined the dataset to be flawed with unverifiable elements from which reliable co

299 al research has an identified methodological flaw, with RCTs having as many limitations as non-RCTs.

300 and a decrease in the time-to-retraction of flawed work.