ライフサイエンスコーパス: flex

1 owth factor; both mouse (m)FLex and human (h)FLex).

2 rotate in the same direction, and the cells flex.

3 genes should result in cells that constantly flex.

4 these filaments, allowing these filaments to flex.

5 site forearm when the elbow joint was slowly flexed.

6 upper limbs aligned to the trunk, and knees flexed.

7 flexors were most active when the wrist was flexed.

8 with the contralateral leg hyperextended or flexed.

9 e responses could be definitely extending or flexing.

10 ischarge cycles and 600 cycles of mechanical flexing.

11 h the humeral shaft with the elbows slightly flexed (20 degrees-30 degrees of flexion).

12 tors, there was unanimous agreement on the P(flex) (+/-3) only 64% of the time.

13 We introduce FLEX, a framework that employs a task-specific informati

14 d CNS tumor classification, we developed MNP-Flex, a platform-agnostic methylation classifier encompa

15 Fms-like tyrosine kinase receptor-3 ligand (FLex; a DC growth factor; both mouse (m)FLex and human (

16 enzyme can adopt different conformations by flexing about the cleft between its two domains, providi

17 MNP-Flex achieved 99.6% accuracy for methylation families an

18 aling over 9,900 slides, we demonstrate that FLEX achieves superior zero-shot generalization to unsee

19 The use of a flex activated mechanophore that does not lead to main c

20 demonstrates an important first step toward flex-activated designs capable of further downstream rea

21 We have discovered a new flex-activated mechanophore that releases an N-heterocyc

22 (12) or metal complexes(13,14), and even by 'flex activation'(15,16).

23 Since the flex-activation is non-destructive to the main polymer c

24 ene caused female-specific lethality because flex(+) acts as a positive regulator of the master switc

25 t of new device concepts taking advantage of flexing, adhesion and friction.

26 a flexible artificial intelligence-guiding (FLEX-AI) wearable sensor that can be operated with a dee

27 ormed for each pharmacophore model using the FlexS algorithm and the three-dimensional structure of 2

28 h the humeral shaft with the elbows slightly flexed allows accurate assessment of the collateral liga

29 different coat environments in the barrel by flexing along a segment at the knee that is free of cont

30 omprehensive fairness analysis confirms that FLEX also effectively mitigates disparities across demog

31 hese representative structures, according to FLEXS, an algorithmically distinct program.

32 and (FLex; a DC growth factor; both mouse (m)FLex and human (h)FLex).

33 ved glycine residues that allow the helix to flex and interact with the bound heme.

34 uate the abilities of 17 stroke survivors to flex and relax the metacarpophalangeal (MCP) joints and

35 hich the two six transmembrane-helix bundles flex and straighten to open and close the pathways on ei

36 the proposed regulatory relationship between flex and Sxl.

37 nanoscale mechanism through which a MOF can flex and the coexistence of phases with different degree

38 stance in which the shoulder and elbow were flexed and the distal skeleton extended.

39 reversed, the cheX mutant cells continuously flexed and were not able to run or reverse.

40 oint alignment also varies as the knee joint flexes and with dynamic activities.

41 electronic sensors able to sense mechanical flexing and capacitance changes.

42 ion confocal microscopy, we have observed OS flexing and disruption in live transgenic Xenopus rods.

43 were 0.799 Nm and 0.428 Nm, when the arm was flexing and extending at 213 degrees per second, respect

44 suction cause rapid and reversible membrane flexing and MG channel activation.

45 ensitive at discriminating cross-sections of flexing and rigid cylinders based on motion cues, when t

46 the coiled coil close to the heads and by a flexing and twisting of the long alpha-helices in the he

47 wall stiffness, setting the limits for cell flexing and, consequently, pore aperture, gas exchange,

48 In patients who had both P(flex) and PEEP(best) determined, there was a close conco

49 When the values of P(flex) and PEEP(best) were interpreted by two additional

50 he curves then were used to determine both P(flex) and PEEP(best), and the results were compared.

51 Whereas wild-type cells ran, paused (flexed), and reversed, cells of all single, double, and

52 hile wild-type cells ran, paused (stopped or flexed), and reversed, the cheX mutant cells continuousl

53 , including limited illumination, instrument flex, and efficiency of vitreous removal.

54 es (P < 0.05) in anthropometrically measured flexed arm muscle mass and grip strength.

55 t-ups for both sexes, pull-ups for boys, and flexed-arm hang for girls), and height and weight, from

56 t can penetrate through the vascular wall in flexing arteries.

57 Our work establishes FLEX as a promising solution for developing more general

58 The LIAISON PLEX Respiratory Flex Assay demonstrated high accuracy, reliability, and

59 in pathogen detection, with the Respiratory Flex Assay detecting analytes missed by SOC assays.

60 The LIAISON PLEX Respiratory Flex Assay is a customizable syndromic molecular assay f

61 The LIAISON PLEX Respiratory Flex Assay was evaluated for respiratory pathogen detect

62 ere tested with the LIAISON PLEX Respiratory Flex Assay-an extended respiratory panel that offers fle

63 e different static standing trials; (1) knee flexed at 0 degrees, (2) knee flexed at 15 degrees, and

64 ials; (1) knee flexed at 0 degrees, (2) knee flexed at 15 degrees, and (3) knee flexed at 30 degrees

65 standing or sitting position with the elbows flexed at 30 degrees .

66 (2) knee flexed at 15 degrees, and (3) knee flexed at 30 degrees before walking at their self-select

67 es shows that 30S head movement results from flexing at two hinge points lying within conserved eleme

68 s of the alpha(gamma) and delta subunits, by flexing between alternative bent and straight conformati

69 valent connection; its movement results from flexing between helices h34 and h35 in a plane orthogona

70 ates of the receptor-ligand bond, that is, a flex-bond.

71 loop, CBL-I, undergoes nanosecond timescale flexing (but not an unwinding), as can be inferred from

72 They also flexed by Brownian motion, exhibiting a persistence leng

73 The PEM Flex camera should enable the functional imaging of brea

74 With enhanced targeting versatility, Flex-Cas12a unlocks access to previously inaccessible ge

75 and cell-based assays show that the variant Flex-Cas12a utilizes 5'-NYHV-3' PAMs that expand DNA rec

76 tery denervation using the single electrode (Flex) catheter or a sham control.

77 sponding pillar linkers, which gives rise to Flex-Cd-MOF-1a and Flex-Cd-MOF-2a, respectively.

78 ic elasticity and microscopic flexibility of Flex-Cd-MOF-2 was observed.

79 re favorable gas-induced dynamic behavior in Flex-Cd-MOF-2a was verified in detail by stepwise C(3)H(

80 kers, which gives rise to Flex-Cd-MOF-1a and Flex-Cd-MOF-2a, respectively.

81 We completed FLEX Cellular Indexing of Transcriptomes and Epitopes by

82 Floxed-inverse (FLEX)-Channelrhodopsin2 (ChR2) expression was targeted t

83 In contrast, the design of the ELIXYS FLEX/CHEM cassette-based synthesizer supports higher tem

84 ines on an expanded cohort (n=29) to confirm FLEX-CITE-Seq findings.

85 images reveal that the nanowires rotate and flex continuously under momentum transfer from the elect

86 everse process involves 1.xEtOH undergoing a flexing contraction transformation on guest exchange to

87 s to detect inflation/deflation of rigid and flexing cylinders, but this handicap can be overcome wit

88 The flex-DBD activation of a 3% hydrogen peroxide solution r

89 ) better than hydrogen peroxide alone or the flex-DBD alone, respectively, for the same treatment tim

90 Flex-DBD operates in ambient air, atmospheric pressure,

91 it design of a dielectric barrier discharge (flex-DBD) with an environmentally safe chemical reagent

92 cular evolution, parameterised using Rosetta Flex ddG predictions, where selection acts to reduce the

93 hus improve the muscle's ability to maintain flexed digits without increasing energetic demands.

94 ocular abnormalities, and CCA by long, thin, flexed digits, crumpled ears and mild joint contractures

95 expansion is comparable to that achieved by FLex DNA encoding native FLex protein.

96 CD8(+) T cells in the presence or absence of FLex DNA-induced DC expansion, but gp120 and mFLex:gp120

97 In FLEX, dopamine release is similar, but not identical to

98 ck east-dipping body that during emplacement flexed down a previously rifted continental margin there

99 the distal half of the mandible is actively flexed downwards and the gape widens to catch flying ins

100 The Flex-DT-IMS is shown to have a resolution >80 and a dete

101 f the flexible DT ion mobility spectrometer (Flex-DT-IMS) with corresponding electrodynamic (Simion 8

102 Paw flexing duration was decreased in both sexes during the

103 In FDM 3DP, commercially produced Flex EcoPLA (FPLA) and polycaprolactone (PCL) filaments

104 The elbow flex-ex sign correctly identified the cause of weakness

105 The elbow flex-ex sign is useful in differentiating between functi

106 ol (EtOH)-containing 1.1.0.96DMF undergoes a flexing expansion transformation on guest exchange to fo

107 orted that loss-of-function mutations in the flex (female-specific lethal on X) gene caused female-sp

108 e best evaluated on the transverse images of flexed fingers.

109 ate for myosin V and used molecular dynamics flexed fitting for model building.

110 to describe dopamine signaling in the brain, FLEX (Flexibly Learned Errors in Expected Reward).

111 A23C also reports the heads up (extended) to flexed (folded) transition in unphosphorylated heavy mer

112 ], FLIPI2, PRIMA-Prognostic Index, m7-FLIPI, FLEX [Follicular Lymphoma Evaluation Index], 23-gene sco

113 ect-injection spark-ignition car (DISI), and flex-fuel car (FFV) represented three different spark-ig

114 In this study, we compare emissions of a flex-fuel Euro-5 GDI vehicle operated with gasoline (E0)

115 reduce genotoxic emissions on this specific flex-fuel GDI vehicle; however, other GDI vehicle types

116 largest share of which is due to legacy GHG flex-fuel vehicle credits that expire in 2016.

117 ther gasoline vehicles should be replaced by flex-fuel vehicles (FFVs) that use ethanol-gasoline blen

118 Nine flex-fuel vehicles meeting Tier 1, light duty vehicle-lo

119 n 2 after viral-mediated transfection of the flexed gene in GlyT2-Cre transgenic mice, evoked fast IP

120 ice using imaging, immunohistochemistry, AAV-FLEX-GFP microinjections, and crosses to RiboTag, Ai95,

121 n, rigidifies the catalytic centers within a flexing GID E3-substrate assembly, and facilitates subst

122 (CD9(+)/PLAP(+)) were used to construct a 4-flex glass strip nanozymatic readout system.

123 synthesized biologically active, oligomeric FLex:gp120 fusion proteins and induced DC expansion (CD1

124 toring, individually calibrated by using the FLEX heart rate method.

125 records and energy expenditure by using the flex heart rate method.

126 low an individually predetermined threshold (flex heart rate) and expressed as a percentage of total

127 The representative Flex-Het SHetA2 effectively inhibited the growth of huma

128 The flexible heteroarotinoids (Flex-Het) represent a novel type of atypical retinoids l

129 dy has revealed a novel mechanism underlying Flex-Het-induced apoptosis involving induction of death

130 Flex-Hets have been shown to induce apoptosis through ac

131 Preclinical studies have shown that Flex-Hets induce apoptosis of cancer cells while sparing

132 llowing tail autotomy, characterized by more flexed hind limb joints.

133 ated with intraindividual variability in the flex HR and sedentary HR range.

134 tiple static and moving objects, including a flexing human hand.

135 One or two ligands are allowed to flex in the procedure, thereby enabling the determinatio

136 1) versus control), and when the leg is more flexed in the step back up, it increases (+9.8 J kg(-1)

137 mutant cells exhibit significantly increased flexing, indicating a role for c-di-GMP in motility.

138 spective, we have shown the beta2 domain can flex into and out of the cleft, forming interactions wit

139 The Tecsoft Flex IOL is a low-cost suitable alternative that is simi

140 ave the way for the investigation of future "flex-ion" inorganic solids and open up a new direction f

141 However, CABS-flex is competitive, particularly when it comes to short

142 The nanoscale mechanism through which they flex is unproven.

143 Rather than flexing, it failed to reverse, and it continually transl

144 While FLEX itself is a general theoretical framework, we descr

145 ased firing of sensory neurons of the FCO at flexed joint angles and is thus functionally similar to

146 onal pledgets and 6, 005 were done with Medi-Flex kits.

147 f 6,005 (5.5%; range, 3.5 to 7.5%) with Medi-Flex kits.

148 femoral instability group walked with a less flexed knee joint and reduced knee flexion and abduction

149 rshooting error occurred at 2 of the 5 least flexed knee joint positions.

150 ly a direct blow to the anterior aspect of a flexed knee.

151 Inc, Fort Worth, TX) or the low-cost Tecsoft Flex lens (Fred Hollows Foundation, Tilganga, Nepal).

152 on of the AcrySof SA60AT lens or the Tecsoft Flex lens.

153 flex lethality is caused by a defect in the functioning

154 By flexing like lattice fencing, the framework couples this

155 All stents except Supera were pinched in flexed limb postures.

156 Most arboreal primates use flexed-limb postures to minimize problems caused by bran

157 Here, we present Flex-LZerD, a framework for docking such complexes.

158 We think that Flex-M coil can easily be used in routine clinical pract

159 s as in routine practice, and sequences with Flex-M coil were also obtained.

160 he conspicuity of images was better with the Flex-M coil.

161 ologists saw more internal openings with the Flex-M coil.

162 he aim of this study was to investigate if a Flex-M superficial coil images would provide more inform

163 formed our experiments with a Bruker timsTOF fleX MALDI-2 instrument in both positive and negative io

164 le time-of-flight mass spectrometer (timsTOF fleX MALDI-2, Bruker Daltonics).

165 on high-throughput workflow from timsTOF Pro/fleX mass spectrometer raw data files to mzML and imzML

166 tation of the technology to a Bruker timsTOF fleX mass spectrometer.

167 The FLEX methodology is expected to provide a practical appr

168 Rapid localization by the T84.66/212 Flex minibody allowed imaging of xenografts at 4 and 19

169 D/g) for the LD minibody and 33%ID/g for the Flex minibody at 6 h following injection.

170 In the T84.66/212 Flex minibody, the human IgG1 hinge plus an additional 1

171 for the LD minibody and 64.9 at 48 h for the Flex minibody.

172 de bond formation in the hinge of the T84.66 Flex minibody.

173 e base mode generates maximal biclusters and flex mode generates less number of clusters and faster b

174 re acquired using an HRA+OCT Spectralis with Flex module (Heidelberg Engineering).

175 tabletop and investigational Spectralis with Flex module devices, both equipped with investigational

176 How to deal with continuously flexing molecules is one of the biggest outstanding chal

177 or only tumble at elevated temperatures via flexing motions of the cavitand.

178 ATP binding or hydrolysis in one subunit to flexing motions of the entire ring.

179 Study Design: The FLEX-MRT trial is an investigator-initiated prospective

180 ts and acquisition modalities on the timsTOF fleX MS.

181 Here we report our contrary findings that flex mutations fail to suppress even the weakest Sxl(M )

182 Key to their conclusion was the ability of flex mutations to suppress the male lethality caused by

183 n analysis platform (510[k]-cleared nCounter FLEX; NanoString, Inc), compared with measurement of pro

184 gearboxes that function through the elastic flexing of a thin-walled cup, called a flexspline.

185 Bending and flexing of DNA may contribute to transcriptional regulat

186 The results lead to the conclusion that flexing of EF-Tu, especially as occurs between its open

187 The method is simple to apply and enables flexing of structures by non-expert modelers.

188 tation of the 30S subunit head domain and in flexing of the anticodon arm of tRNA suggests that they

189 sting of both N- and C-terminal helices, and flexing of the C-terminal helix.

190 , motion of the heads could still occur by a flexing of the coiled coil close to the heads and by a f

191 We observe torsional flexing of the entire complex and a rotational sub-step

192 Interdomain flexing of the enzyme and a localized excursion of the c

193 The observed flexing of the glacier suggests that seawater is trapped

194 atrix stiffness and, consequently, increased flexing of the guard cells under turgor pressure, genera

195 ric nucleosome, which may allow for enhanced flexing of the histone core in vivo.

196 ft closure of the nucleotide-binding pocket, flexing of the lower body beta-sheet and a radial expans

197 The beam bending is correlated with flexing of the surface-bound molecular muscles, whereas

198 PV curve was measured that demonstrated a P(Flex) of 16-18 cm H2O.

199 f PEEP was not adequately predicted by the P(Flex) of the PV curve.

200 P predicted by the lower inflection point (P(Flex)) of the PV curve.

201 cture formed by the fusion of several bones, flexing only where it meets the skull.

202 near the wrists while asking the patient to flex or extend the normal arm at the elbow and simultane

203 s was separately randomized to receive Super Flex or Parasol punctal plugs.

204 ither FS-LASIK or LASIK, while comparable to FLEX or PRK/LASEK group based on the results from ORA.

205 to the fibers that functioned as handles to flex or stretch a fiber.

206 sion did not vary with the contralateral hip flexed or extended, but it was larger when the ipsilater

207 problems in cracking and delamination during flexing or heating.

208 t angles during mouse locomotion (e.g., most-flexed passive response mouse with most-extended publish

209 he fourth, alternatively, both extending and flexing passive responses could be definitely present.

210 interfacing the system with micro-drives or flex-PCB cables for recording from multiple brain region

211 Instead we show that the lethal flex phenotype depends on the absence of a Y chromosome,

212 cleotide polymorphisms (SNPs) using the UGbS-Flex pipeline.

213 as performed using the 10X Genomics Chromium Flex platform.

214 plugs were retained compared to 32% of Super Flex plugs.

215 0) investigated the safety and efficacy of V-Flex Plus coronary stents (Cook Inc) coated with escalat

216 d into each canine external iliac and/or the flexing portion of the proximal femoral artery.

217 apable of learning to hold the hindlimb in a flexed position (response) if shock (outcome) is deliver

218 immobilization with the limb in the plantar flexed position resulted in marked upregulation of both

219 er time, they learn to maintain the leg in a flexed position that minimizes net shock exposure.

220 ats were trained to maintain a hind leg in a flexed position to avoid noxious stimulation.

221 ection can learn to maintain a hind leg in a flexed position to minimize exposure to a noxious electr

222 is extended learn to maintain that leg in a flexed position, a simple form of instrumental learning.

223 ked, rats learned to maintain their leg in a flexed position, exhibiting progressively longer flexion

224 b is extended learn to maintain the leg in a flexed position.

225 vealed a pit feature containing a child in a flexed position.

226 Rats quickly learn to maintain the leg in a flexed position.

227 sh human cadaveric hands in the extended and flexed positions were obtained before and after arthrogr

228 used interchangeably to describe a laterally flexed postural deviation in Parkinson's disease (PD), t

229 tural state and motor tasks in promoting the flexed posture of the upper extremity were assessed.

230 chanically and chemically robust, and can be flexed precisely to a predetermined curvature with compl

231 alcohol pledgets were compared with the Medi-Flex Prep Kit II for skin disinfection before venipunctu

232 to that achieved by FLex DNA encoding native FLex protein.

233 between the heads is lost, allowing them to flex randomly about the junction with the tail; this cou

234 Flex-RV also integrates a programmable machine learning

235 Flex-RV pioneers an era of sub-dollar open standard non-

236 Here we present Flex-RV, a 32-bit microprocessor based on an open RISC-V

237 ors, including force resisting sensor (FRS), flex sensor (FLS), MEMS accelerometer, and Piezoelectric

238 eloped a cost-effective dataglove using five flex sensors, an inertial measurement unit, and a powerf

239 that a model of the tiger stripes as tidally flexed slots that puncture the ice shell can simultaneou

240 n emission mammography (PEM) camera, the PEM Flex Solo II.

241 Cone scale xylem in flexing species is tough, but poorly conductive.

242 The protocol is included in the CABS-flex standalone package along with online documentation

243 s: coarse-grained simulations using the CABS-flex standalone package and an all-atom reconstruction-o

244 Airway opening pressure (P-Flex), static lung compliance (Crs), and trapped gas vol

245 ergoing implantation of the Gianturco-Roubin flex stent were prospectively entered into the Gianturco

246 994, nine centers implanted Gianturco-Roubin flex stents as an unplanned new device in the initial tr

247 Control procedures such as passive leg flexing, stimulation of the central end of the cut tibia

248 es a self-cleaving ribozyme with traditional FLEx switches to deliver molecular cargo to specific neu

249 ddition, we report a tamoxifen-inducible Cre-FLEX system that allows the activation of mutant histone

250 mice were bilaterally injected with AAV-EF1a-flex-taCasp3-TEVp once into the ARC or PVN to specifical

251 We used the Cre-dependent vector AAV1-EF1a-Flex-taCasp3-TEVP to lesion NAc MOR-expressing cells.

252 We have studied the flexed-tail (f) mouse to gain insight into mammalian mit

253 The flexed-tail (f) mutant mice exhibit normal steady-state

254 Flexed-tail animals have axial skeletal abnormalities an

255 ere gait defect due to an inability to dorsi-flex the hindpaws.

256 thly (P < 0.05) and activates the flexors to flex the joints faster (P < 0.05), in comparison to part

257 cause of improper activation of muscles that flex the knee.

258 reflex response, subjects were then asked to flex the neck as quickly as possible after onset of the

259 these oceans are heated by tidal forces that flex the solid moon (rock plus ice) during its eccentric

260 provided by different subunits and that this flexes the beta-sheets of the lower body and enlarges th

261 ys cytokine engagement to JAK2 activation by flexing the pseudokinase domain hinge.

262 Moreover, by flexing the substrate, the lens position can be adjusted

263 t angles and is thus functionally similar to flexing the tibia.

264 Participants were instructed to flex their elbow to 90 degrees while tensing an elastic

265 s in varied positions-neutral, extended, and flexed, their cervical spine musculoskeletal responses w

266 ly evidence measurement of individual lipids flexing through telltale rapid correlated vibrational sh

267 In flight animals, the knee joint was more flexed throughout the stroke, there was a narrower range

268 mplexes shows that a portion of helix H6 can flex to accommodate the differently sized inhibitors sug

269 ion in the measured clotting time, even when flexed to a 35 mm bend radius.

270 30 are not necessarily elongated but somehow flexed to allow IL-6 classic signaling.

271 d-f-block bimetallic, even though the ligand flexes to allow a variable U-M separation.

272 x and receptor cargo, and appears capable of flexing to conform to curved vesicular membranes.

273 f the hands, causing fingers to irreversibly flex toward the palm with significant loss of function.

274 Two media, Multi-Microbe and Flex Trans, were tested and found to be equally acceptab

275 Prevailing vulnerabilities in flexing transfer capabilities for care or capacity reaso

276 This frequency-labeled exchange (FLEX) transfer principle is applied to detect previously

277 - 1, 4-benzenedicarboxylate) as it undergoes flexing transformations during the guest exchange betwee

278 n the multilength scale understanding of MOF flexing transformations, which will support future desig

279 14.67) for continued alendronate use in the FLEX trial.

280 on Trial (FIT), the FIT Long-Term Extension (FLEX) trial, and the Health Outcomes and Reduced Inciden

281 P-Flex was also greatest in the 15 Hz group, followed by t

282 linically relevant test showed the Biomatrix Flex was the most resistant to deformation and the Eleme

283 %), versus femtosecond lenticule extraction (FLEX) was - 0.01 (95% CI, - 0.31 to 0.30; p = 0.972; I(2

284 P(flex) was determined in 19 (68%), a PEEP(best) in 24 (86

285 The heme thereby serves as a flexing wedge, allowing the N-terminal subdomain of H-NO

286 RUBic can operate on two modes, base and flex, where base mode generates maximal biclusters and f

287 conformation when the backbone is allowed to flex, will not be pruned.

288 Membranes flex with changes in transmembrane potential as a result

289 interaction (PPI), docking studies (GOLD and Flex-X) followed by molecular dynamics (MD) simulation s