ライフサイエンスコーパス: flexibility

1 icon electrode (0.025 muA/muM) and excellent flexibility.

2 ctical skills were related to inhibition and flexibility.

3 er capability, energy density, lifespan, and flexibility.

4 porphyrin core in an attempt to modulate its flexibility.

5 tration can simplify the process and provide flexibility.

6 It exhibits substantial conformational flexibility.

7 taic efficiency, low manufacturing cost, and flexibility.

8 nonuniform developmental features of neural flexibility.

9 participate in the preservation of metabolic flexibility.

10 r core; however, helix 8 showed considerable flexibility.

11 developed at the CPT that allow maximum user flexibility.

12 accessibility, and (iii) its conformational flexibility.

13 tic dopamine release, and enhances cognitive flexibility.

14 option, adds to their strategy of increased flexibility.

15 ts activation loops with high conformational flexibility.

16 is necessary for homeostasis and behavioral flexibility.

17 signaling drives state-dependent behavioral flexibility.

18 and reinforcement and can enhance cognitive flexibility.

19 especially in systems with higher structural flexibility.

20 l feature of adaptive memory is its inherent flexibility.

21 he scene, thereby maximising the measurement flexibility.

22 specific deficits in OFC-mediated cognitive flexibility.

23 dominant change being an increase in protein flexibility.

24 in-binding proteins to confer robustness and flexibility.

25 h but reduced memory fidelity and behavioral flexibility.

26 circuits important for memory to reduce this flexibility.

27 nformational changes that indicates how this flexibility accommodates the mismatch between the 3- and

28 oint of 15-20 degrees C indicates changes in flexibility across ~40% of the protein structure that is

29 ing of this learning and attenuated response flexibility after changes in the action-outcome continge

30 iral binding strength by increasing antibody flexibility, allowing for adaption to imperfectly conser

31 Env flexibility also contributes to the ability of HIV-1 to

32 ense suggests a high degree of immunological flexibility among vertebrates, which may advance our und

33 modulate gene expression in order to provide flexibility and adaptability to eukaryotic organisms.

34 nding of one agonist leads to conformational flexibility and an increase in conformational spread at

35 (NHEJ). We characterized LINP1 structure and flexibility and analyzed interactions with the NHEJ fact

36 Owing to the flexibility and biocompatibility, the lipid-based nanoca

37 a possible framework for modeling cognitive flexibility and building more flexible artificial intell

38 The BTO layers show excellent flexibility and can form well-ordered and periodic wrink

39 ur market with an ageing workforce, employee flexibility and choice are key to retention and wellbein

40 stics of medicine and the value of teamwork, flexibility and collaboration.

41 se in retinal cones, limiting their adaptive flexibility and color vision.

42 These data reveal surprising flexibility and context-dependence in the control of int

43 g of H-bond dynamics could contribute to the flexibility and crystallinity of the material--two criti

44 he high-resolution structure, conformational flexibility and distribution of S trimers in situ on the

45 The flexibility and diversity of this outreach program creat

46 physical characteristics of plastics such as flexibility and durability, producers enrich materials w

47 amic Coupling Index to quantify the relative flexibility and dynamic coupling at a site-specific, sin

48 However, despite the promise of synthetic flexibility and electronic design, fabrication of 2DPs t

49 te, striking a balance between stability and flexibility and enabling plasticity in information proce

50 estigate the relationship between behavioral flexibility and experience-dependent regulation of EAAT2

51 cheminformatics Python stack, increasing the flexibility and extendibility of the tool compared to ex

52 ll mapped onto the regions of conformational flexibility and functional importance, indicating that t

53 tical pathway may be critical for behavioral flexibility and functional independence in older age.

54 n approach to enhance metabolic activity and flexibility and improve memory CD8 T cell differentiatio

55 dern machine-learning algorithms in terms of flexibility and learning speed.

56 supramolecular polymers with increased fiber flexibility and lower degrees of polymerization.

57 The membrane shows high flexibility and mechanical strength, owing to the improv

58 e inhibition is a core function of cognitive flexibility and movement control.

59 HybISS design allows for increased flexibility and multiplexing, increased signal-to-noise,

60 he discovered feedback motifs increase model flexibility and performance on learning tasks.

61 lt in local and delocalized increases in Tpm flexibility and prominent coiled-coil twisting in pseudo

62 community, which already exhibited increased flexibility and promiscuity relative to the other commun

63 ng conditions, herbivores and humans had the flexibility and resilience to adapt, demonstrating the i

64 restrictive vegan diet decreases nutritional flexibility and robustness, increasing risk for vulnerab

65 ues for immuno-MS assays and demonstrate its flexibility and robustness.

66 uses flexible and printed electronics where flexibility and scalability are required, i.e., for sens

67 ng coherence times of nuclear spins with the flexibility and scalability of quantum dot systems.

68 results provide a mechanistic picture of how flexibility and size of HA and aggrecan lead to the brus

69 Our analysis revealed that the proximity, flexibility and solvent exposure of the tyrosines are th

70 es visual discrimination learning, cognitive flexibility and specifically attentional set-shifting.

71 vature-inducing activity to provide membrane flexibility and stability to limit mechanical stress imp

72 Nucleosome flexibility and the amplitude of nucleosome motions such

73 ears in order to modulate the conformational flexibility and the peptide character of peptidomimetic

74 ongly depend on the polyelectrolyte backbone flexibility and the solvent quality.

75 compliance have significantly increased the flexibility and usability of this software package.

76 The flexibility and versatility of the strategy have been il

77 factors such as high temperature, moisture, flexibility and water resistivity has been investigated

78 igning SemRep to increase its modularity and flexibility, and addressing weaknesses identified in the

79 position has a unique combination of length, flexibility, and chemistry to act as an effective latch

80 be essential for understanding the accuracy, flexibility, and dynamics of human visual recognition.

81 H6 displays poorly cooperative fold, higher flexibility, and kinetic instability, and a higher dynam

82 cognitive functions: General Ability, Speed/Flexibility, and Learning/Memory.

83 shed light on the interplay among stability, flexibility, and responsiveness of neuronal collective d

84 ific traits, associated with the behavioural flexibility animals need for adapting to seasonal and un

85 cs in mouse chromaffin cells, indicating TMD flexibility as a mechanistic determinant that facilitate

86 ar arginine absence, both cell types display flexibility as their formation can be restored with sele

87 ty and selectivity, including limited ligand flexibility, as observed by ligand preorganization and 3

88 NA with increased precision, efficiency, and flexibility, assays to identify off-target editing are b

89 tegrity of antigens and local conformational flexibility at antigenic sites, which may elicit a more

90 ironments while concomitantly providing them flexibility between different configurations, which may

91 ed between the SurA domains, with structural flexibility between domains assisting OMP recognition, b

92 d5 complex particles, which revealed extreme flexibility between the Wnt/Fzd-CRD and the Fzd-TM regio

93 To behave adaptively with sufficient flexibility, biological organisms must cognize beyond im

94 gest that ripened samples with certain local flexibility but important structural homogeneity present

95 AD51 remains stably bound independent of DNA flexibility, but rapidly dissociates from flexible DNA w

96 t channels, crystal size controls structural flexibility by altering the number of repeating units, w

97 Neuromodulation evolved to allow for such flexibility by dynamically updating the effectivity of t

98 nting to the importance of PFo in behavioral flexibility by generating control over the switching of

99 length distribution, chain conformation, and flexibility can also be accessed within poly(fluorene) n

100 rom H3 nucleosomes by revealing that DNA end flexibility can be fine-tuned in a sequence-dependent ma

101 ses the remaining challenges of scalability, flexibility, cladding impermeability, and performance at

102 -temperature processing as well as excellent flexibility compared to polymer substrates.

103 ant chemical characteristics but also brings flexibility, cost-effectiveness, swiftness and user-frie

104 The characteristic flexibility, defined chemical topology, and length scale

105 al learning, a behavioral test for cognitive flexibility dependent on repeated LTP.

106 Given not only their structural flexibility depending on the number of OH functions and

107 Given not only their inherent structural flexibility depending on the type of guest gas molecules

108 Cognitive flexibility depends on a fast neural learning mechanism

109 ur study highlights the concept of molecular flexibility during early cell-type specification, with b

110 While tools to assess cognitive flexibility during early infancy are lacking, we aimed t

111 ay prevented weight loss in ABA and improved flexibility during early reversal learning by reducing p

112 iotemporal developmental features of "neural flexibility" during the first 2 y of life.

113 lso excellent mechanical properties, such as flexibility, elasticity, and processability.

114 Cognitive flexibility enables appropriate responses to a changing

115 ic environment due to protein conformational flexibility enables direct excitation of low-lying charg

116 e of the unique characteristics of strength, flexibility, etc., of textiles, utilizing a fundamentall

117 SH3, it becomes more structured, but retains flexibility even in the fully engaged state.

118 ght loss in ABA and improvement of cognitive flexibility following suppression of mPFC-AcbSh activity

119 sive domain motions but maintains sufficient flexibility for catalysis.

120 luorescent probes has provided unprecedented flexibility for choosing regions of interest in recordin

121 Design flexibility for dinuclear VT complexes confers an advant

122 es with a thermoresponsive hydrogel provides flexibility for encapsulating therapeutics in a reversib

123 timescale, providing the necessary cognitive flexibility for sampling from highly dynamic environment

124 This architecture provides flexibility for the adhesive tip of the CshA fibril to m

125 an algorithm named peakonly, which has high flexibility for the detection or exclusion of low-intens

126 ultrafast response/recovery times, and good flexibility for various volatile organic compounds.

127 rally requires miniaturization, integration, flexibility, good workability at room temperature and in

128 Thus, MR-derived neural flexibility has the potential to reveal the underlying n

129 tofrontal cortex-that it mediates behavioral flexibility-has been challenged by the finding that disc

130 d dehydrobutyrine (Dhb) display considerable flexibility in a variety of chemical and biological reac

131 with brain regions known to govern cognitive flexibility in adults and exhibited unique characteristi

132 might be associated with preserved cognitive flexibility in ASD should be further examined.

133 bstrates, we show that there is considerable flexibility in both the choice of substrate binders (bin

134 have poor fits to empirical data and lack of flexibility in capturing variation in growth rate.

135 strating the general importance of metabolic flexibility in cell health.

136 t sites in mosquito genomes and the inherent flexibility in CGD design obviates the concern that DRAs

137 Considering the flexibility in compositional tuning and immediate synthe

138 ogenesis, which grants the system additional flexibility in converting electron donors.

139 ese findings help to explain the mechanistic flexibility in drug/H(+) coupling observed in MdfA and m

140 h 15 chemical elements, the tool offers high flexibility in formula attribution.

141 d for ClpAP protease activity, although some flexibility in how the AAA+ ring docks with ClpP may be

142 e surveillance interventions while attaining flexibility in implementation across different health ca

143 tion as a developmental mechanism underlying flexibility in innate behaviour.

144 wise unobtainable, as well as allow the host flexibility in its capacity to cope with changing enviro

145 een shown to be a powerful tool due to their flexibility in modeling the aggregate CNV effects, their

146 esearch and a number of Reviews have covered flexibility in MOFs.

147 the red-shifted cyanine dyes offer spectral flexibility in multiplexed imaging experiments and enhan

148 ), In metal, and In(III) opens up additional flexibility in precursor selection.

149 e of commercial wireless hardware allows for flexibility in programming and provides a streamlined up

150 an evolutionary process by which phenotypic flexibility in response to environmental variation is re

151 nsion between standardisation and supporting flexibility in safety management.

152 ndividual consistency in gregariousness, but flexibility in social associates, demonstrating that ind

153 d oxidation, glucose oxidation and metabolic flexibility in soleus muscle cells from ABA-treated mice

154 Flexibility in spring migration timing of long-distance

155 IGNIFICANCE STATEMENT Everyday life requires flexibility in switching between several rules.

156 Its user-friendly construct design, greater flexibility in targeting genomic regions, and cost-effec

157 inding, suggesting that this mutant also has flexibility in the activation gate and is subject to tra

158 The insert region has larger conformational flexibility in the GDP-bound Cdc42 than in the GTP-bound

159 demonstrated the need for pronounced overall flexibility in the PRORP1 enzyme conformation for substr

160 her mutations also appear to act by reducing flexibility in the protein.

161 underdetermined systems, displaying greater flexibility in the range of reaction fluxes than experim

162 Impaired cognitive flexibility in visual reversal-learning tasks has been o

163 long arabinan side-chains maintain cell wall flexibility in water deficit.

164 striatal neural interactions, and cognitive flexibility, in unanaesthetized common marmosets (Callit

165 acid oxidation, maintained glucose metabolic flexibility, increased nonoxidative glucose disposal rel

166 Using the Dynamic Flexibility Index and the Dynamic Coupling Index to quan

167 ion between alpha(1C) and beta-subunits, (2) flexibility-inducing polyglycine substitutions in the I-

168 inding sites on the SL receptor and that its flexibility is a major determinant of its interactions w

169 intents in different contexts, but how this flexibility is achieved at the level of neural circuits

170 nt concentration, suggesting tissue nutrient flexibility is an important mechanism allowing biomass r

171 Flexibility is further given for inclusion of any set of

172 s, and why humans' unprecedented cooperative flexibility is nevertheless culturally parochial.

173 ic penalty associated with restricting ssDNA flexibility is offset by a strong RAD51-RAD51 interactio

174 Inter-individual variability in behavioral flexibility is widespread throughout the animal kingdom,

175 in macaques, the classic test of behavioral flexibility, is unaffected when lesions are made by exci

176 S exhibits extensive conformational flexibility: it modulates exposure of its receptor-bindi

177 Based on these studies, the mechanistic flexibility known to exist at other steps of NHEJ is now

178 ABX(3) perovskite structure with mechanical flexibility, light weight, and eco-friendly processing.

179 This flexibility may explain the low activity in vitro and su

180 macronutrient composition of diet (metabolic flexibility) may be informative of individuals' suscepti

181 hese data suggest that sigma1 conformational flexibility modulates the efficiency of reovirus host ce

182 egulatory system that provides the speed and flexibility needed for mitochondrial coordination far be

183 ACC is necessary for this form of behavioral flexibility, nor have any studies shown that ACC acts by

184 Thus, deficits in behavioral flexibility observed in disorders linked to dopamine per

185 To understand how this genome flexibility occurs within a rigidly conserved shell, we

186 The flexibility of a Bayesian framework is promising for GWA

187 We propose that the temporal flexibility of a GRN is a general prerequisite for its p

188 The increased flexibility of a pyridine-4-yl-methanethiol ligand due t

189 e of optimal experimental design: due to the flexibility of complex models, it is difficult to intuit

190 ues (Pavlovian-to-instrumental transfer) and flexibility of cue-outcome associations (reversal learni

191 n in controlling both cue reactivity and the flexibility of cue-reward associations.

192 GEO12CF provides insights into the metabolic flexibility of Dehalococcoides and could be used to figh

193 with mathematical modeling to show that the flexibility of DNA positively correlates with nucleation

194 a new general framework suggesting that the flexibility of DNA, which may increase locally as a resu

195 cterization of changes in the conformational flexibility of EF-G in response to FusB binding and show

196 ges in both the structure and conformational flexibility of EF-G, but which of these changes drives F

197 Mutational studies demonstrated that the flexibility of Emc4 and the hydrophilicity of the client

198 tational theories.SIGNIFICANCE STATEMENT The flexibility of episodic memory allows us to remember bot

199 ultidomain rigidity, reducing conformational flexibility of F-actin-binding domains via interdomain c

200 wn to be lateralized, but the provenance and flexibility of hemispheric specialization remain open qu

201 s essential for understanding the remarkable flexibility of human brain function despite having to re

202 ing by transcription and reveal a remarkable flexibility of interphase chromosomes.

203 These findings help explain the flexibility of leatherwood and also call into question t

204 The results report on the intrinsic flexibility of LHCII pigment-protein complexes in a memb

205 poral aspect of DNA data with the additional flexibility of modeling the sampled chromosomes that con

206 d here for elucidating increased rigidity or flexibility of MscL when bound to various phospholipids.

207 delicate equilibrium between robustness and flexibility of neural responses to external stimuli.SIGN

208 We demonstrate the power and flexibility of our approach on receptive fields, ion cha

209 We demonstrate the robustness and flexibility of our structured and non-local model for di

210 to underpin biomolecular recognition and the flexibility of protein-binding sites.

211 de reduced to a few cents, combined with the flexibility of rHLA technology, this poses an attractive

212 We hypothesized, given the flexibility of SH3 binding peptides, that their binding

213 these structures depends on the coordinative flexibility of silver and the 2-formyl-1,8-napthyridine

214 e transfection and the length of alkyl tail, flexibility of sterol ring and polarity due to -OH group

215 lecular mechanisms explaining the functional flexibility of T(H)17 cells with regard to environmental

216 ics simulations allow us to characterize the flexibility of the cage in the solvent, the (rare) guest

217 d mechanical strength, owing to the improved flexibility of the CAM-Ag nanofibers with bonded chain s

218 to control its DNA cleavage activity through flexibility of the catalytic HNH domain.

219 ve this curvature rather than increasing the flexibility of the DNA.

220 unctional theory, providing insight into the flexibility of the figure-eight and guidance for future

221 of the gamma9delta2TCR and required membrane flexibility of the gamma9delta2TCR and CD277, facilitati

222 These results highlight the strong flexibility of the global bird migration system and offe

223 strated that the GAd capsid fiber shared the flexibility of the HAd5 equivalent for permitting geneti

224 d shape of the guest in combination with the flexibility of the host.

225 The flexibility of the LDM for a variety of microbiome studi

226 Moreover, by changing the flexibility of the linker between two binding motifs, ou

227 ganelles, as well as the number, length, and flexibility of the linker proteins that mediate contact

228 i) binding kinetics depend on the length and flexibility of the linker that connects both domains of

229 ver, previous approaches were limited in the flexibility of the linking function, which has proved pr

230 Inherent reliability and flexibility of the model have been shown.

231 These findings demonstrate the exceptional flexibility of the octopus arm and provide a basis for i

232 r dynamic simulations of STK17B revealed the flexibility of the P-loop and a wide range of R41 confor

233 d to unexpected insights into the remarkable flexibility of the parasite, addressing the dependency o

234 ar the peptide-binding site while increasing flexibility of the peptide-binding site turret loop.

235 hat Akt autoinhibition depends on the length/flexibility of the PH-kinase linker.

236 the catalytic properties of the MOF and the flexibility of the polymer.

237 is pre-M1 displacement is facilitated by the flexibility of the S2-M4 of GluN1 and GluN2A.

238 py experiments show that water increases the flexibility of the supramolecular polymer and decreases

239 phosphorylation induces local changes in the flexibility of the TCR zeta-chain, this naturally leads

240 We also established that conformational flexibility of the two HEPN domains is important for pro

241 curacy has, as yet, been only limited by the flexibility of the wavefunction ansatz used.

242 The flexibility of these models is shown by adapting the DNA

243 cuits, our results highlight the algorithmic flexibility of this motif beyond disinhibition due to th

244 dissect natural variation in the behavioral flexibility of two Caenorhabditis elegans wild strains.

245 Results showed that neural flexibility of whole brain, motor, and high-order brain

246 The conformational flexibility of Y731 and the hydrogen-bonding interaction

247 Porous materials exhibiting framework flexibility offer unique opportunities to tune these pro

248 Here we assess the effect of this flexibility on the results of functional magnetic resona

249 xible (>40% deuteron incorporation), and its flexibility only decreases in the beta-folded state.

250 ional control, working memory, and cognitive flexibility, particularly during tasks involving simulta

251 The inherent glycan complexity and backbone flexibility require single-molecule approaches for real-

252 the structural basis of AAV Rep's structural flexibility required to fulfill its multifunctional role

253 mpowers the spinal cord with the computation flexibility required to perform appropriate sensorimotor

254 After multiple years of flexibility, residents continue to report a high rate of

255 table SIRT1 in the liver abrogated metabolic flexibility, resulting in systemic insulin resistance, h

256 over time in the developing wing and 2) this flexibility results from the fact that every single gene

257 as in wide frequency ranges coupled with the flexibility, scalability, and ease of solution processin

258 formance requires high degrees of mechanical flexibility, sensing capability, and user-friendly simpl

259 ibes to PFo an important role for behavioral flexibility.SIGNIFICANCE STATEMENT We can flexibly adapt

260 club," comprising brain regions with neural flexibility significantly higher than whole-brain neural

261 The new entry format provides a greater flexibility, simplifies maintenance and allows the captu

262 KET-induced behavioral deficits in cognitive flexibility, social interaction, and novel object recogn

263 dinary nanostructural properties, remarkable flexibility (soft polymeric mechanics having hard inorga

264 Control of hardness, flexibility, solubility and function of the material wer

265 s robust and tunable genome editing granting flexibility, speed and uniformity at less cost, leading

266 -insular network activation during cognitive flexibility task performance in individuals with ASD.

267 al circuits must be modulated for behavioral flexibility, the ability to adapt to environmental chang

268 Yet, despite its extreme evolutionary flexibility, the locus has rigidly conserved structural

269 ributions that are of intermediate levels of flexibility: the class of proportional normal distributi

270 e conventional textiles their characteristic flexibility, thinness, anisotropic strength and porosity

271 expression values for each cell and provide flexibility to account for common features of scRNA-seq:

272 in the brain, probably allowing for a higher flexibility to adapt to highly novel environmental stimu

273 pacity to detect innumerable hazards and the flexibility to adapt to new ones.

274 While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here

275 ingle mated pairs and therefore may lack the flexibility to buffer pathogen pressure with increased g

276 model the dispersion of species which lacks flexibility to catch a single species' distinctiveness.

277 Our data suggest p53 has the flexibility to cooperate with a variety of transcription

278 es (CSSEs) with multiple phases have greater flexibility to customize and combine the advantages of s

279 proaches or on using structures with limited flexibility to guide the design.

280 he rigid enzyme takes advantage of substrate flexibility to induce a conformation that facilitates th

281 nascent H2 helix may provide conformational flexibility to initiate binding, whereas those species t

282 The flexibility to learn diverse tasks is a hallmark of huma

283 partments provides plants with the metabolic flexibility to maintain physiological levels of acetate

284 l treatments provide a significant degree of flexibility to tailor microbial membranes to meet specif

285 loop participate in assembly and also impart flexibility to the tube while maintaining its integrity.

286 d oligomeric states and their conformational flexibility, together with ligand-binding site and inter

287 This flexibility translates into an ensemble of ACE2 homodime

288 g issues related to measurement of cognitive flexibility using a combination of metrics with ecologic

289 s on ssDNA and dsDNA differing in length and flexibility using surface plasmon resonance.

290 f inter-individual differences in behavioral flexibility using the model nematode C. elegans.

291 rocess of switching shares similarities with flexibility, very limited studies have been devoted spec

292 Metabolic flexibility was defined as the change in 24-h RQ from EB

293 significantly higher than whole-brain neural flexibility, were consistent with brain regions known to

294 ts on cardiomyocyte YM: Acetylation provides flexibility, whereas detyrosination imparts rigidity.

295 als near the aggregation periphery exhibited flexibility, whereas others were consistent.

296 They often exhibit a high degree of flexibility, which can be essential for their function.

297 have introduced certain relevant elements of flexibility, which were not intrinsic to the original BC

298 understanding of the degree of immunological flexibility wild animals present, information that is ev

299 hrough the application, which allows greater flexibility with sharing, reannotating and organizing da

300 A foundation of human cognition is the flexibility with which we can represent any object as ei