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2 omimetic building blocks containing backbone-fluorinated 1,4-disubstituted 1,2,3-triazole moieties.
8 oselectivity in glycosylations with a set of fluorinated alcohols as well as carbohydrate acceptors.
9 s (SiPcs, 1-7) with non-, partially- and per-fluorinated aliphatic (linear or branched at the alpha-c
10 ence of fluorination on the lipophilicity of fluorinated aliphatic alcohols was determined, and the l
12 r for catalysts bearing one triflate and one fluorinated alkoxide than for catalysts bearing two trif
15 reaction is successful with a range of alpha-fluorinated alkyl sodium sulfinate salts and diarylphosp
17 5.1.0]octanes) based on a domino reaction of fluorinated alpha-bromoenones with beta-amino alcohols w
19 with sterically unhindered monomers using a fluorinated aluminum salph complex with a substoichiomet
20 nt synthesis methods for the construction of fluorinated amines rely on air and moisture sensitive re
24 g reaction at the C-terminal position of the fluorinated amino acid was conveniently performed under
26 arting materials in the preparation of novel fluorinated amino acids, anilines, and aliphatic amines
29 eatment of [LFe3(PhPz)3OFe][OTf]2 (1) or its fluorinated analog [LFe3(F2ArPz)3OFe][OTf]2 (5) with iod
30 ilable by this method serve as precursors to fluorinated analogs of sugars, amino acids, and other va
31 active compounds, and their enantioenriched fluorinated analogs should be of great interest in the s
32 2) /H(2) mixture, in comparison with the non-fluorinated analogue (43 h(-1) ) and a Au/TiO(2) heterog
33 lso report the synthesis and reactivity of a fluorinated analogue and the structure of its covalently
34 od was applied for gram-scale synthesis of a fluorinated analogue of G protein-coupled receptor antag
35 tituted azobenzene core and its tetra- ortho-fluorinated analogue, we have developed a set of uni- an
36 lysaccharide, LPS), we designed a library of fluorinated analogues aiming for an [(18)F]-labeled radi
38 eaction has been applied to the synthesis of fluorinated analogues of diltiazem and tiazesim, both th
40 application, the synthesis of a new class of fluorinated analogues of the neuroprotective tripeptide
41 port a new elemental ionization method where fluorinated analytes are introduced into an ICP to produ
42 er, contains a combination of chiral-racemic fluorinated and achiral hydrogenated dendrons (RHF) in i
43 ms are explored by ab initio calculations of fluorinated and hydrogenated diamond (111) surfaces inte
44 ted backbones, which incorporate hydrophobic fluorinated and hydrophilic sulfonic acid functional gro
47 rination approach enables the development of fluorinated and radiofluorinated compounds that can be d
48 is, heteroaryl-substituted acetaldehydes are fluorinated and then directly engaged in enantioselectiv
51 blished C(sp(2))-H oxidative addition of the fluorinated arene as the selectivity-determining step of
52 en dictated by the innate electronics of the fluorinated arene, limiting the synthetic utility of the
53 otocatalytic C-F functionalization of highly fluorinated arenes is a powerful method for accessing fu
54 The mechanism of C(sp(2))-H borylation of fluorinated arenes with B(2)Pin(2) (Pin = pinacolato) ca
55 )benzene, as well as a C-F bond in partially fluorinated arenes, to furnish borylation products under
59 inding protein) using commercially available fluorinated aromatic amino acids and fluorinated precurs
60 n/Prophenol-catalyzed Mannich reaction using fluorinated aromatic ketones as nucleophilic partners fo
61 C-H bond silylation is facile with partially fluorinated aromatic substrates containing two ortho flu
63 rst racemization-stable helicene derivatives fluorinated at terminal rings, 1,2,3,4-tetrafluoro[6]hel
65 LCE to analogs prepared from classical and m-fluorinated azobenzene derivatives, the origin of the pe
66 e findings demonstrate that incorporation of fluorinated azobenzenes not just may alter photophysical
68 non-covalent interactions between side-chain fluorinated benzyl esters and main-chain terminal arenes
71 alternative strategy, we present the use of fluorinated boronic acid-appended pyridinium salts in co
72 cal fluorination, we prepared a series of 11 fluorinated branched-chain amino acids and evaluated the
74 oute to the stereoselective synthesis of key fluorinated building blocks of high value for medicinal
75 ted by gold species meet species with either fluorinated building blocks or fluorinating reagents, ne
80 e calculated transition states show that the fluorinated catalysts have stronger N-H...O and C-H...F
82 e fluorine effect on the reactivity of alpha-fluorinated CH acids has remained largely unexplored.
83 th a C(12)-hydrogenated chain and a C(4)F(9)-fluorinated chain emerged as the most potent additive ex
84 sts of a hydrogenated chain, and a partially fluorinated chain made of a propyl hydrogenated spacer t
87 atalytic enantioselective synthesis of alpha-fluorinated chiral tertiary alcohols from (hetero)aryl m
90 when lactate was the electron donor, and the fluorinated compound was the sole electron acceptor.
93 mulate TCE dechlorination, while some of the fluorinated compounds in certain AFFF formulations can i
94 measurements due to the rising importance of fluorinated compounds in pharmaceutical, environmental,
95 e the occurrence and identity of replacement fluorinated compounds in surface water and sediment of t
97 c-pressure elemental ionization method where fluorinated compounds separated by gas chromatography (G
98 ented, enabling the measurement of log P for fluorinated compounds with or without UV activity regard
99 n provide refinement of such models with the fluorinated compounds, which allows the explanation of t
100 as altered, shorter-chain PFAS and volatile fluorinated compounds, which were scrubbed effectively w
104 of determining the sorption kinetics of any fluorinated contaminant, this work also highlights the s
105 yields (19)F T2 NMR relaxation values of any fluorinated contaminant, which are among the most danger
107 arboxylate substrates, highly functionalized fluorinated cyclobutenes were obtained in excellent yiel
108 tain environmentally friendly chiral-racemic fluorinated dendrons in their hydrophobic part (RF), one
109 les, zinc phthalocyanine and its eight-times fluorinated derivative, with tunable energy levels based
110 ography (PET) radioligand [(11)C]RSR-056, 38 fluorinated derivatives were synthesized and tested by i
112 a C-F bond driven Diels-Alder reaction of a fluorinated dienophile and a borole that shows remarkabl
113 ow that we can achieve the production of the fluorinated diketide 2-fluoro-3-hydroxybutyrate at appro
115 ition of silylated nucleobases onto model C2-fluorinated dithioacetal substrates resulted in 1,2-syn
117 successfully applied them to characterize a fluorinated drug molecule, aprepitant, and its commercia
118 sitive spin for probing molecular details of fluorinated drug substances in solid formulations, due t
121 ither artificially preformed or derived from fluorinated electrolytes, and thus, the effect of the Li
122 high-concentration electrolytes, and highly fluorinated electrolytes, surface coatings that can form
123 oping, core-shell hollow host structure, and fluorinated ether electrolytes enables ultrastable Li st
124 In this work, we synthesize a new class of fluorinated ether electrolytes that combine the oxidativ
125 work we explore how an electrolyte additive (fluorinated ethylene carbonate - FEC) mediates the thick
126 e with fluoromalonyl-CoA allows insertion of fluorinated extender units at 43% of the yield of the wi
127 sease (COPD) by using free-breathing dynamic fluorinated (fluorine 19 [(19)F]) gas magnetic resonance
128 lic alphagammaalpha-tripeptides derived from fluorinated-furanoid sugar amino acid frameworks act as
129 onic structure calculations, we predict half-fluorinated GaBi honeycomb under tensile strain to harbo
130 e computed the electronic spectrum of a half-fluorinated GaBi nanoribbon with zigzag edges, which sho
131 n MR imaging during inhalation of a normoxic fluorinated gas mixture (perfluoropropane) and by using
133 rs took potentially confounding medications (fluorinated glucocorticoids and/or intravenous immunoglo
137 on to more economically friendly small-chain fluorinated groups is leading to a resurgence in the syn
138 nes, esters, nitriles, primary amides, alpha-fluorinated halo-acetates and perfluoroalkyl iodides.
144 bust bonds; consequently, the degradation of fluorinated hydrocarbons is exceptionally difficult.
146 n conjunction with our previous work on PNAs fluorinated in backbone and at N-terminus, it is evident
150 e and pyrazole was shown by the synthesis of fluorinated Isocarboxazid and Mepiprazole analogues.
153 phosphorylated, hydroxylated), and labeled (fluorinated, isotopically labeled) side chains to be add
154 ullerene organic solar cells (OSCs) based on fluorinated ITIC-Th1 electron acceptor and a wide-bandga
156 perfluoropolyether (PFPE), formulated these fluorinated ligands as aqueous nanoemulsions, and then m
157 This work demonstrates the usefulness of fluorinated ligands in designing molecule-selective and
158 ce four fluorine atoms from OFCP to generate fluorinated macrobicyclic compounds that display dual-tu
159 copolymers, providing facile access to semi-fluorinated macromolecules using a single methodology wi
160 ssing, fabrication, and functionalization of fluorinated materials with easy removal of the volatile
162 y for the fabrication of a chemically stable fluorinated metal-organic framework (MOF) material (NbOF
163 rate construction of a hydrolytically stable fluorinated metal-organic framework (MOF), NbOFFIVE-1-Ni
165 current work ortho-fluorinated (OF) and meta-fluorinated (MF) analogs of (18)F-para-fluorinated (PF)-
166 ayer and intralayer space of two-dimensional fluorinated MOFs for capturing acetylene from ethylene.
168 Comparison of different monolayer-forming fluorinated molecules reveals important differences in r
169 Various applications could benefit from new fluorinated molecules that offer chemical handles for qu
170 literature associated with the metabolism of fluorinated molecules, focusing on examples where the pr
171 We have been investigating the mechanism of fluorinated monomer insertion by three of the six differ
173 control of the polymerization of main chain fluorinated monomers as exemplified by vinylidene fluori
174 TREN (TREN = tris(2-aminoethyl amine)), semi-fluorinated monomers with side chains containing between
176 roof-of-principle level with a library of 13 fluorinated monosaccharides to a set of three carbohydra
177 d potentially problematic outcomes with some fluorinated motifs and are enhancing our understanding o
180 NT mimic structures via the self-assembly of fluorinated nanohoops, which can be synthesized in a sca
183 report the identification of two subsets of fluorinated nonxanthine A(2B) adenosine receptor antagon
184 minium ions were successfully generated from fluorinated O-acetyl-N,O-acetal l-tartaric acid derivati
185 ), we investigated in the current work ortho-fluorinated (OF) and meta-fluorinated (MF) analogs of (1
186 nents that uses a mobile liquid interface (a fluorinated oil) to reduce the adhesive forces between t
187 The development of new fluids has focused on fluorinated olefins, known as hydrofluoroolefins (HFOs),
189 afer and shows higher thromboresistance than fluorinated, omniphobic catheter surfaces, produced by p
190 and highly efficient OPV devices using both-fluorinated or both-nonfluorinated donor/acceptor blends
191 ite the growing interest in the synthesis of fluorinated organic compounds, few reactions are able to
195 Given the wide use and emerging concerns of fluorinated organics (e.g., per- and polyfluoroalkyl sub
198 The utility of Tf2NH-TiCl4 activation of fluorinated oxazaborolidines is documented by examples i
199 ional functionalities and the formation of 3-fluorinated oxindoles exhibiting an array of four adjace
201 meta-fluorinated (MF) analogs of (18)F-para-fluorinated (PF)-NB1, a 3-benzazepine-based radiofluorin
202 AFFF primarily containing electrochemically fluorinated PFASs for 10 days, followed by a 6 day depur
204 oxy groups as bioisosteric replacements of a fluorinated phenyl ring and properties such as lipophili
206 soft hydrogel as a conductor and an elastic fluorinated photoresist as the passivation insulation la
207 d was demonstrated on both unfluorinated and fluorinated plastics, demonstrating high tracer recoveri
208 rse phase HPLC show higher hydrophobicity of fluorinated PNA oligomers, dependent on the number and s
209 ne and at N-terminus, it is evident that the fluorinated PNAs have potential to emerge as a new class
211 the authors show a highly efficient route to fluorinated poly(aryl thioethers) via an organocatalyzed
212 erein, we report a highly efficient route to fluorinated poly(aryl thioethers) via an organocatalyzed
213 remarkable reactivity enable rapid access to fluorinated poly(aryl thioethers), but also opens new av
214 of the volatile catalyst and TMSF byproducts.Fluorinated poly(aryl thioethers), unlike their poly(ary
215 can be used as a monomer in vivo to produce fluorinated poly(hydroxyalkanoate) (PHA) bioplastics wit
216 ize polymer mechanochemistry to synthesize a fluorinated polyacetylene, a long-sought-after air-stabl
218 ated by laser-desorption of the near-planar, fluorinated polycyclic aromatic hydrocarbon (PAH), C60H2
219 A modular synthesis of regiospecifically fluorinated polycyclic aromatic hydrocarbons (PAHs) is d
220 assembling giant surfactants consisting of a fluorinated polyhedral oligomeric silsesquioxane (FPOSS)
222 luorocarbon emulsion polyplexes containing a fluorinated polymeric CXCR4 antagonist (F-PAMD) as an si
223 cleaved from the backbone of the side-chain fluorinated polymers coated on the fibers and then trans
224 hat, among others, degradation of side-chain fluorinated polymers in the environment and landfills ca
227 n of these molecules, leading to a series of fluorinated polysubstituted imidazoles in gram scale.
228 ailable fluorinated aromatic amino acids and fluorinated precursors as example applications of the me
230 egarding the toxicity and adverse effects of fluorinated processing aids on humans and the environmen
234 analogues thus expand the scope of available fluorinated proline analogues as tools to tailor proline
236 uous flow synthesis of highly functionalized fluorinated pyrazoles and pyrazolines has been developed
238 ave led to the ever-increasing popularity of fluorinated pyrazoles in various areas of science are di
240 w, analysis of novel synthetic approaches to fluorinated pyrazoles that appeared in recent years is p
245 ylacetates, the synthetic equivalence of the fluorinated reagent with alpha-nitro-alpha-diazo carbony
248 lohexyl and linear aliphatic amines could be fluorinated selectively at the gamma-methyl and methylen
250 his, two cholesterol analogs with truncated, fluorinated side chains have been synthesized and shown
254 ce for forming cobalt-aryl bonds adjacent to fluorinated sites are the origin of the high regioselect
255 ne illustrates the potential ease with which fluorinated small molecules relevant to neuroscience dru
256 g the potential to generate a broad range of fluorinated small-molecule targets in living cells.
257 of the HFC solvent in tandem with the highly fluorinated, solubilizing, weakly coordinating [Al(OR(f)
258 y simply modulating the starting peptide and fluorinated solvent concentrations during synthesis.
260 omniphobic surface that can super-repel even fluorinated solvents, which highly wet all materials.
261 (19)F long-lived states in suitably designed fluorinated spy molecules allows one to perform competit
263 s is observed and calculated for planar ring-fluorinated stilbenes, trans-2,3,5,6,2',3',5',6'-octoflu
264 ) and difluoromethoxy (OCF(2) H) groups are fluorinated structural motifs that exhibit unique physic
266 luoroalkyl substances (PFASs) are a group of fluorinated substances of interest to researchers, regul
268 yl)pyrrolidin-2-one derivatives, bearing the fluorinated substituent on a tetrasubstituted carbon.
269 presence of the highly electron-withdrawing fluorinated substituent, cyclic alpha-trifluoromethylate
270 e chemo- and stereoselective construction of fluorinated substituents, such as the trifluoromethyl (C
271 n, we employed (19)F NMR in conjunction with fluorinated substrate analogs to directly measure pK(a)
272 d herein, several alternative substrates and fluorinated substrate analogs were prepared to investiga
274 describe the field of reactions of partially fluorinated substrates with transition metal atoms, ions
276 e of substrates to give medicinally relevant fluorinated substructures with complete regiocontrol.
277 can be employed to synthesize unprecedented fluorinated sugars and steroids, and it can also be appl
278 lity, reactivity and interaction features of fluorinated sugars are described, as well as their appli
280 nly describes a new synthetic application of fluorinated sulfones, but also provides a new route to f
281 This work demonstrated the utilization of fluorinated sulfur ylides as versatile reagents for Core
282 ane at room temperature, gives rise to novel fluorinated tetrahydrofuran-fused tetrahydroquinolines i
285 for medicinal chemists to access a range of fluorinated therapeutic candidates with distinct physico
286 a wide bandgap polymer donor PM6 containing fluorinated thienyl benzodithiophene (BDT-2F) unit and a
287 The antiparallel self-assembled pore of the fluorinated tripeptides illustrates the selective ion-tr
289 metric properties of urea and thiourea-based fluorinated tripodal receptors are explored here for the
291 The aims of this study were to screen novel, fluorinated, TSPO radiotracers for susceptibility to the
293 n and metabolism of [(18)F]F-HPA-12, a radio-fluorinated version of the ceramide analog N-(3-hydroxy-
295 this protocol, we quantified the amount of a fluorinated xenobiotic (heptafluorobutyric acid, HFBA) i
299 onance imaging (iCEST MRI) and TF-BAPTA as a fluorinated Zn-binding probe with micromolar sensitivity
300 stances were tentatively identified, and non-fluorinated zwitterionic betaine compounds, which are co