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1 The most recent of these are labeled with fluorine-18.
2 olabeling with the positron-emitting isotope fluorine-18.
3 .83 nM) were selected for radiolabeling with fluorine-18.
4 emission tomography if they are labeled with fluorine-18.
5 cells and suitability for radiolabeling with fluorine-18.
6 scaffolds that were yet to be labelled with fluorine-18.
7 s that are labeled with both fluorescein and fluorine-18.
8 with a positron-emitter, either carbon-11 or fluorine-18.
9 ssion tomographic (PET) radiopharmaceutical, fluorine 18 ((18)F) 2-fl uoropropionyl labeled PEGylated
11 dient-echo MRI was performed to quantify MH, fluorine 18 ((18)F) flortaucipir (AV-1451) PET was perfo
13 tudy, a public NSCLC data set that contained fluorine 18 ((18)F) fluoro-2-deoxyglucose positron emiss
14 malignant brain lesions can be depicted with fluorine 18 ((18)F) fluorocholine positron emission tomo
15 mals were then injected with (99m)Tc ECDG or fluorine 18 ((18)F) fluorodeoxyglucose (FDG) (0.037-0.07
16 s) were compared with those of animals given fluorine 18 ((18)F) fluorodeoxyglucose (FDG) (n = 15, al
18 ures of tumor metabolism and perfusion using fluorine 18 ((18)F) fluorodeoxyglucose (FDG) dedicated b
19 cyte-M-CSF (GM-CSF) and its implications for fluorine 18 ((18)F) fluorodeoxyglucose (FDG) imaging of
20 sessment of tissue-specific insulin-mediated fluorine 18 ((18)F) fluorodeoxyglucose (FDG) influx rate
22 derwent MRI, and four participants underwent fluorine 18 ((18)F) fluorodeoxyglucose (FDG) PET imaging
23 D), mild cognitive impairment, or neither at fluorine 18 ((18)F) fluorodeoxyglucose (FDG) PET of the
24 ke in specific brain regions, detected using fluorine 18 ((18)F) fluorodeoxyglucose (FDG) PET, is a v
25 th tumors who underwent clinically warranted fluorine 18 ((18)F) fluorodeoxyglucose (FDG) PET/CT foll
27 y advanced breast cancer initially staged at fluorine 18 ((18)F) fluorodeoxyglucose (FDG) PET/CT or a
28 rpose To investigate the prognostic value of fluorine 18 ((18)F) fluorodeoxyglucose (FDG) PET/CT para
29 a using contemporary whole-body (WB) MRI and fluorine 18 ((18)F) fluorodeoxyglucose (FDG) PET/CT prot
30 f the left breast, bilateral breast MRI, and fluorine 18 ((18)F) fluorodeoxyglucose (FDG) PET/CT were
32 onents of glucose metabolism, exemplified by fluorine 18 ((18)F) fluorodeoxyglucose (FDG) positron em
34 e the performance characteristics of interim fluorine 18 ((18)F) fluorodeoxyglucose (FDG) positron em
36 (CT) of the chest, abdomen, and pelvis; and fluorine 18 ((18)F) fluorodeoxyglucose (FDG) positron em
38 iodine studies, as well as PET studies using fluorine 18 ((18)F) fluorodeoxyglucose, gallium 68 ((68)
39 ance and correlation with tumor viability of fluorine 18 ((18)F) fluoromisonidazole (FMISO) uptake in
42 that positron emission tomography (PET) with fluorine 18 ((18)F) fluorthanatrace (FTT) depicts activa
43 d finding that was further investigated with fluorine 18 ((18)F) flurodeoxyglucose (FDG) positron emi
44 identify quantitative imaging biomarkers at fluorine 18 ((18)F) positron emission tomography (PET) f
46 icipants also underwent translocator protein fluorine 18 ((18)F)-DPA-714 PET for neuroinflammation.
48 ogic outcome in these patients compared with fluorine 18 ((18)F)-fluorocholine and (18)F-PSMA-1007 PE
50 2025, participants with PSMA-avid disease at fluorine 18 ((18)F)-piflufolastat PET/CT performed withi
53 dy, we have synthesized labeled AVT-011 with fluorine-18 ((18)F) followed by in-vitro and in-vivo ana
54 Among the beta(+)-emitting radionuclides, fluorine-18 ((18)F) is the isotope of choice for PET, an
57 zed alkyl Heck reaction as a mild and robust fluorine-18 ((18)F) radiochemical approach for positron
58 h possibilities have accelerated progress in fluorine-18 ((18)F) radiochemistry with numerous methods
59 antigen (PSMA) with gallium-68 ((68)Ga) and fluorine-18 ((18)F) radiotracers has aroused tremendous
62 usefulness of fluorodesoxyglucose marked by fluorine-18 ((18)F-FDG) positron emission tomography (PE
64 an amyloid PET scan with 1 of 3 AB tracers (fluorine 18 [18F]-labeled florbetapir, 18F-labeled florb
66 chest wall, and mediastinum were filled with fluorine-18 activities based on the average radionuclide
67 tsburgh Compound-B, the 110 min half-life of fluorine-18 allows for wider utilization in research and
68 thesis, and biological characterization of a fluorine-18 analog of dasatinib, a multitargeted kinase
69 ty were synthesized (4, 5, and 6), and their fluorine-18 analogs were evaluated for use as positron e
73 d probes were labeled with the radioisotopes fluorine-18 and tritium, as well as a fluorescent tag.
74 galectin-3 inhibitors were radiolabeled with fluorine-18 and used as surrogate PET tracers of TD139 a
75 imaging (positron emission tomography (PET)/fluorine-18) and treatment (targeted radionuclide therap
80 olecules labelled with the unnatural isotope fluorine-18 are used for positron emission tomography.
82 , are particularly challenging to label with fluorine-18 because they are densely functionalized and
84 ize aromatic substrates with the radioactive fluorine-18 but its scope is restricted to arenes contai
85 riven radiochemistry for three key isotopes: fluorine-18, carbon-11, and zirconium-89, and their appl
86 acid (N-MeFAMP), have been radiolabeled with fluorine-18, characterized in amino acid uptake assays,
88 ase detection rate of PSMA-based PET/CT with fluorine 18-DCFPyL as a radiotracer and the PET-directed
92 months after vaccination, including cardiac fluorine 18 FDG PET/MRI, blood biomarkers, and health-re
94 ated with focused ultrasound, as measured by fluorine-18 florbetaben positron-emission tomography.
95 als, to compare PSMA to other agents such as fluorine 18 fluciclovine and carbon 11 choline, and to h
97 nts analysis (PCA) was applied to dynamic 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG) positron emis
98 e introduced on non-attenuation-corrected 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG) positron emis
101 phy angiography), those with high hepatic 2-[fluorine-18]fluoro-2-deoxy-D-glucose uptake had higher n
103 obtained after administration of 2-deoxy-2-[fluorine-18]fluoro-D-glucose in 39 patients with probabl
104 ith micro-PET by using the radiotracer 9-(4-[fluorine 18]-fluoro-3-hydroxymethylbutyl)-guanine (FHBG)
107 minutes after injection of 370 MBq (10 mCi) fluorine 18 fluorodeoxyglucose ((18)F-FDG) followed by p
108 analysis, the role of metabolic imaging with fluorine 18 fluorodeoxyglucose (FDG) in breast cancer is
109 lculation of the percentage injected dose of fluorine 18 fluorodeoxyglucose (FDG) in tumor from small
112 s and possible CS who were investigated with fluorine 18 fluorodeoxyglucose (FDG) PET/CT and cardiac
113 lly suspected underwent clinically indicated fluorine 18 fluorodeoxyglucose (FDG) PET/CT and, immedia
114 and to identify differences between WAT and fluorine 18 fluorodeoxyglucose (FDG) PET/CT proven cold-
115 baseline magnetic resonance (MR) imaging and fluorine 18 fluorodeoxyglucose (FDG) positron emission t
117 ively compare the sensitivity of a dedicated fluorine 18 fluorodeoxyglucose (FDG) positron emission t
118 luate the positive predictive value (PPV) of fluorine 18 fluorodeoxyglucose (FDG) positron emission t
119 aging technique in body imaging is currently fluorine 18 fluorodeoxyglucose (FDG) positron emission t
120 he correlation between metabolic activity at fluorine 18 fluorodeoxyglucose (FDG) positron emission t
121 Purpose To assess the diagnostic accuracy of fluorine 18 fluorodeoxyglucose (FDG) positron emission t
123 he established patterns of hypometabolism on fluorine 18 fluorodeoxyglucose (FDG) positron emission t
124 trinsic contrast of melanin in comparison to fluorine 18 fluorodeoxyglucose (FDG) positron emission t
125 cal-pathologic nodal status with use of four fluorine 18 fluorodeoxyglucose (FDG) positron emission t
126 ss significant (P < .05) differences between fluorine 18 fluorodeoxyglucose (FDG) uptake of benign le
128 acilitate future direct correlations between fluorine 18 fluorodeoxyglucose (FDG)-avid colonic lesion
129 ts suspected of having abdominal or thoracic fluorine 18 fluorodeoxyglucose (FDG)-positive lesions un
131 phic (CT) and (18)F-fluorodeoxyglucose ( FDG fluorine 18 fluorodeoxyglucose ) PET/CT examinations wer
132 Histograms of administered activity for fluorine 18 fluorodeoxyglucose and iodine 131 sodium iod
134 ermined with findings of decreased uptake of fluorine 18 fluorodeoxyglucose at PET, shrinkage of tumo
135 olving a labeled dose of 370 MBq (10 mCi) of fluorine 18 fluorodeoxyglucose is estimated to involve a
136 nt contrast material-enhanced MR imaging and fluorine 18 fluorodeoxyglucose PEM in randomized order;
137 y (PET) and coregistered computed tomography/fluorine 18 fluorodeoxyglucose PET are used primarily in
138 rials and Methods Between 2010 and 2013, 219 fluorine 18 fluorodeoxyglucose PET examinations were per
139 etail methods for controlling the quality of fluorine 18 fluorodeoxyglucose PET imaging conditions to
141 public data set of multimodality images (CT, fluorine 18 fluorodeoxyglucose PET, and T1-weighted MRI)
142 s gallium 68 DOTA-Tyr3-octreotide PET/CT and fluorine 18 fluorodeoxyglucose PET, play an increasing r
143 t (Fig 1), bilateral breast MRI (Fig 2), and fluorine 18 fluorodeoxyglucose PET/CT (Fig 3) were perfo
145 l of 30 lesions were evaluated at (18)F- FDG fluorine 18 fluorodeoxyglucose PET/CT and (18)F- FPPRGD2
146 ure to compare the diagnostic performance of fluorine 18 fluorodeoxyglucose PET/CT and diffusion-weig
147 5 years) who underwent health screening with fluorine 18 fluorodeoxyglucose PET/CT between January 20
148 xaminations, as well as clinically indicated fluorine 18 fluorodeoxyglucose PET/CT examination within
149 trointestinal malignancies underwent two FDG fluorine 18 fluorodeoxyglucose PET/CT examinations withi
150 n lesions presents a further challenge where fluorine 18 fluorodeoxyglucose PET/CT has a potential ro
151 ted MRI is comparable or superior to that of fluorine 18 fluorodeoxyglucose PET/CT in the differentia
154 background is recommended in multicenter FDG fluorine 18 fluorodeoxyglucose PET/CT studies on the bas
155 serial cross-sectional imaging (CT, MRI, or fluorine 18 fluorodeoxyglucose PET/CT) between April 201
156 -grade tumors, they were also evaluated with fluorine 18 fluorodeoxyglucose PET/CT, with imaging find
158 ighted MRI showed significant agreement with fluorine 18 fluorodeoxyglucose PET/MRI for treatment res
159 ndmark finding relied on the use of clinical fluorine 18 fluorodeoxyglucose positron emission tomogra
161 es after injection, compared with (18)F- FDG fluorine 18 fluorodeoxyglucose uptake with SUVmax maximu
162 2.3) at 60 minutes, compared with (18)F- FDG fluorine 18 fluorodeoxyglucose uptake with SUVmax maximu
163 patients (20.7%) with adequate follow-up had fluorine 18 fluorodeoxyglucose-avid IMLN, with a median
164 CT scans is feasible and may be helpful when fluorine 18 fluorodeoxyglucose-avid masses that are not
165 ough positron emission tomography (PET) with fluorine-18 fluorodeoxyglucose ((18)F-FDG) has a major i
166 al (IB) routes and imaged sequentially using fluorine-18 fluorodeoxyglucose ((18)FDG) uptake as a non
167 y (PET) using nitrogen-13 (N-13) ammonia and fluorine-18 fluorodeoxyglucose (FDG) for imaging of perf
168 pectively investigated the value of PET with fluorine-18 fluorodeoxyglucose (FDG) for preoperative ch
169 hat positron emission tomography (PET) using fluorine-18 fluorodeoxyglucose (FDG) may be useful for d
170 ing optimal interpretative criteria (IC) for Fluorine-18 fluorodeoxyglucose (FDG) Positron Emission T
171 , and two underwent gallium scintigraphy and fluorine-18 fluorodeoxyglucose (FDG) positron emission t
172 a marker for tissue viability with regional fluorine-18 fluorodeoxyglucose (FDG) uptake in patients
178 erapy with both computed tomography (CT) and fluorine-18 fluorodeoxyglucose positron emission tomogra
179 hereas vascular inflammation was assessed by fluorine-18 fluorodeoxyglucose uptake on positron emissi
180 (molecular biology) and imaging diagnostic (fluorine-18 fluorodeoxyglucose-positron emission tomogra
181 ing of malignancy, bone marrow activity from fluorine 18-fluorodeoxyglucose (FDG) PET may be informat
182 onclusion A model that includes pretreatment fluorine 18-fluorodeoxyglucose PET texture features from
183 anatomic localization and classification of fluorine 18-fluorodeoxyglucose PET uptake patterns in fo
184 d 20 nonsmoking control subjects underwent 2 fluorine 18-fluorodeoxyglucose positron emission tomogra
190 tudy was to evaluate the prognostic value of fluorine-18-fluorodeoxyglucose PET/CT imaging of venous
192 magnetic resonance imaging and angiography, fluorine-18-fluorodeoxyglucose positron emission tomogra
193 ed to segment and quantify serial changes in fluorine-18-fluorodeoxyglucose uptake for veins of inter
194 s, positron emission tomography imaging with fluorine-18-fluorodeoxyglucose, and cardiac magnetic res
196 ing positron emission tomography (PET) with [fluorine-18]fluorodopa (F18-DOPA), we compared the integ
200 nium-mediated uronium deoxyfluorination with fluorine-18 followed by deprotection, accomplished withi
207 lled modular build-up approach), introducing fluorine-18 in a fast and efficient manner in a building
208 by late-stage radiofluorination, introducing fluorine-18 in the last step of the synthesis, or by a b
209 Compounds 3a and 6a were radiolabeled with fluorine-18 in two steps and utilized in positron emissi
210 for SULT1E1 can be labeled with carbon-11 or fluorine-18, in vivo assays of SULT1E1 functional activi
214 dopamine synthesis capacity was measured by fluorine-18-l-dihydroxyphenylalanine (F-18-FDOPA) positr
215 [(18)F]tetrabutylammonium fluoride to afford fluorine-18 labeled (hetero)arenes in high radiochemical
218 he purpose of this study was to synthesize a fluorine-18 labeled, highly selective aldosterone syntha
219 pairment aged 65 to 85 years who completed a fluorine 18-labeled (18F)-florbetapir positron emission
222 orylated tau pathologic findings measured by fluorine 18-labeled AV-1451 ([18F]AV-1451) positron emis
224 here have been conflicting results regarding fluorine 18-labeled fluorodeoxyglucose ((18)F-FDG) PET/M
227 o undergo low-dose PEM with up to 185 MBq of fluorine 18-labeled fluorodeoxyglucose ((18)F-FDG).
233 aracteristics, AB burden (as measured with a fluorine 18-labeled-florbetapir PET scan), objective and
234 amyloid positron emission tomography (PET); fluorine 18-labeled-fluorodeoxyglucose PET; and/or magne
236 x (10(6) p/s/cm(2)/sr)] but similar level of fluorine-18-labeled 2'-fluoro-2'-deoxyarabinofuranosyl-5
237 ic positron emission tomography imaging with fluorine-18-labeled 2-fluoro-2-deoxyglucose ((18)FDG) li
238 1, and glycolytic genes, hk1 and pdk1, lung fluorine-18-labeled 2-fluoro-2-deoxyglucose ligand uptak
239 foundation for the future construction of a fluorine-18-labeled 5-ALA PET tracer to be used for func
240 her accumulation (P < 0.05) of 18F-FEAU than fluorine-18-labeled 9-(4-fluoro-3-hydroxymethylbutyl)gua
244 p-tau181 and NfL measurements and at least 1 fluorine-18-labeled fluorodeoxyglucose (FDG) positron em
245 Although inflammation can be measured using fluorine-18-labeled fluorodeoxyglucose positron emission
246 based labeling method was used to synthesize fluorine-18-labeled insulin specifically B(1)-(4-[(18)F]
247 on, we first developed a small peptide-based fluorine-18-labeled PET imaging agent, [(18)F]DK222, whi
249 cross-linking noninvasively, we developed a fluorine-18-labeled positron emission tomography agent (
254 pha-tertiary haloamides to the corresponding fluorine-18 labelled alpha-tertiary fluoroamides with no
256 lucose homeostasis was studied in mice using fluorine-18 labelled glucose molecular imaging probes an
258 Further advances are being made with other fluorine-18-labelled and generator-based PET tracers, th
261 eatures but uncertain clinical diagnosis had fluorine-18-labelled-fluorodeoxyglucose-PET at The Feins
262 de scaffold to facilitate radiolabeling with fluorine-18 or carbon-11 positron-emitting nuclides and
266 temetamol injection labeled with radioactive fluorine 18 positron emission tomography imaging for bra
267 (PTC) (e.g. kryptofix 2.2.2) associated with fluorine-18 preparation has been found to be detrimental
268 l molecules, peptides, and proteins with the fluorine-18 prosthetic [(18)F]4-fluorophenylboronic acid
271 series of candidates, radiolabeled them with fluorine-18 radioisotope, and determined their physicoch
272 for the lead compound PEGMeDAS and automated fluorine-18 radiolabeling afforded [(18)F]PEGMeDAS in 25
275 4), magnetic resonance imaging (n = 3), and fluorine-18 sodium fluoride positron emission tomography
278 ter, either carbon-11 (t(1/2) = 20.4 min) or fluorine-18 (t(1/2) = 109.7 min), and included (i) repla
281 and benefiting from the longer half-life of fluorine-18 (t(1/2) = 109.8 min), facilitating broader a
282 with either carbon-11 (t(1/2) = 20.4 min) or fluorine-18 (t(1/2) = 109.8 min), so allowing the append
285 ctively targeting the ghrelin receptor using fluorine-18 tagged entities would allow localization and
289 -1 (sigma1) receptors were radiolabeled with fluorine-18 via displacement of the corresponding mesyla
290 temetamol injection labeled with radioactive fluorine 18 (Vizamyl; GE Healthcare) administration foll
291 temetamol injection labeled with radioactive fluorine 18 was safe and had high sensitivity and specif
294 y of nucleophilic aromatic substitution with fluorine-18, we describe two complementary procedures fo