ライフサイエンスコーパス: fly

1 r motility (walking, crawling, swimming, and flying).

2 dopamine in acting to maximise reward on the fly.

3 t species: lesser mealworm and black soldier fly.

4 nts necessary for their establishment in the fly.

5 arget gene relationships in human, mouse and fly.

6 establishes the metabolic state of the adult fly.

7 er in a subset of clock neurons of the fruit fly.

8 ation pathway increase with age in wild-type flies.

9 era, such as Drosophila, mosquitoes and sand flies.

10 fic joint angles, elicits pausing in walking flies.

11 -receptor dissociation rates of relevance to flies.

12 in humans and MSL (male-specific lethal) in flies.

13 f active vision on flight motor responses in flies.

14 or Slit-C does not repel axons in Slit-null flies.

15 ces may contribute to sex-specific ageing in flies.

16 e X chromosome resulted in lethality in male flies.

17 nsmitted through the bite of infected tsetse flies.

18 the defining member of the ncBAF complex in flies.

19 ain activity imaging even in copulating male flies.

20 e accessibility of promoters prior to ZGA in flies.

21 of fluralaner against three species of filth flies.

22 athways also mediate nutritional immunity in flies.

23 L. major transmission by L. longipalpis sand flies.

24 is slowed down in long-lived insulin mutant flies.

25 tome showed dramatic changes in the Clk(jrk) flies.

26 as warrant novel tools for management of the flies.

27 t, with separate testing for male and female flies.

28 ction process are, however, scarce for fruit flies.

29 e and acetylcholine co-stimulation in living flies.

30 ction (IBIN) was diminished in osa knockdown flies.

31 restores normal PKA activation in amn mutant flies.

32 reased during drone flights, at any altitude flown.

33 Flies 3 to 5 days old were exposed to compounds in the f

34 paths, and the tendency to pass obstacles by flying above them, provide new insights into the strateg

35 The innate immune induction in fly Adar mutants is suppressed by silencing of Dicer-2,

36 In contrast, flying adults use an enlarged opsin set in a sexually di

37 We found that each bird continued to fly along its preferred trajectory up to a point very cl

38 responses are observed in CRISPR-engineered flies and human epithelial cells whose Naked/NKD HisC ha

39 ncentration in substrates used by both adult flies and larvae.

40 en shown to have diverse functions in yeast, flies and mammals, including stress-responses.

41 al protein (Rp) genes adversely affects both flies and mammals.

42 Here we show, using flies and mice, that sleep deprivation leads to accumula

43 I, which is much faster acting against fruit flies and mosquitoes.

44 levels of reactive oxygen species in glia in flies and murine Schwann cells.

45 However, treatment of flies and primary Schwann cells with an antioxidant supp

46 ntal DA release from a single neuron in live flies and report optogenetically elicited nigrostriatal

47 Insecticide-susceptible horn flies and stable flies were tested topically.

48 ilar to previously reported architectures of fly and bovine DHX36.

49 ed the olfactory physiology of the screwworm fly and compared it with the non-obligate ectoparasitic

50 analyzed in detail, especially in the fruit fly and desert locust, understanding of the organization

51 lecularly and structurally conserved between fly and human TRIM32.

52 pregulating mitochondrial metabolism in both fly and mammalian adipose tissue, which likely contribut

53 In both fly and mouse models, genetic ablation of Sestrins preve

54 prevents degenerative phenotypes observed in fly and rat neurons.

55 It has long been proposed that flying and swimming animals could exploit neighbour-indu

56 tion of numerous miRNAs in cells of mammals, flies, and nematodes, thereby specifying the half-lives

57 el systems, including yeast, nematode, fruit fly, and zebrafish, and discuss emerging methods for cre

58 In the whole brain of flies, anesthesia disrupts rafts and PLD(null) flies res

59 he fastest steering response observed in any flying animal, so far.

60 In a highly dynamic airspace, flying animals are predicted to adjust foraging behaviou

61 Some flying animals use active sensing to perceive and avoid

62 e hydrodynamic traits shared by swimming and flying animals.

63 ic and anticyclonic parts of the vortices to fly apart.

64 c area for visceral leishmaniasis (VL), sand flies are abundant for a short period of <=3 months.

65 Our findings in flies are congruent with observation in human exposed to

66 Lutzomyia longipalpis sand flies are the major natural vector of Leishmania infantu

67 , the feasibility of using the black soldier fly as a tool for waste valorization and feed production

68 e long-range transport and wet deposition of fly ash from the combustion of coal (likely from Western

69 In contrast, an incinerator fly ash pretreatment showed a progressive decrease in me

70 Lacking the ability to fly away from predators, this desert insect has extremel

71 es of chemosensory genes in the citrus fruit fly B. minax provided new insights for preventive contro

72 ble element isolated from the Oriental fruit fly, Bactrocera dorsalis, is distantly related to both t

73 e-like levels of neural activity even though flies become unresponsive to mechanical stimuli.

74 dual heterozygous rutabaga/+ and octbeta1r/+ flies behave like the wild-type control.

75 most of the locomotor actions that underlie fly behaviors.

76 olumes (<10 muL) and in just 5 min of on-the-fly bioassay.

77 d they likely represent not only the largest flying birds of the Eocene but also some of the largest

78 Individuals exposed to sand fly bites develop humoral and cellular immune responses

79 Pre-exposure to uninfected sand fly bites or immunization with defined sand fly salivary

80 ably caused by insufficient exposure to sand fly bites.

81 that inflict trauma on multiple parts of the fly body, including the head.

82 d a recent electron microscope volume of the fly brain [4] to reconstruct the fine anatomy of individ

83 that polyploid cells accumulate in the adult fly brain and that polyploidy protects against DNA damag

84 thousands of neurons across a volume of the fly brain during spontaneous sleep and compared this to

85 t kind of sleep this is, how the rest of the fly brain is behaving, or if any specific sleep function

86 tified a single pair of neurons in the fruit fly brain that directly senses 'blood' glucose levels an

87 e created the most detailed map of the fruit fly brain to date, identifying over 25,000 neurons and 2

88 te wake-promoting clock neurons in the fruit fly brain.

89 at, similar to humans and other vertebrates, flying bumblebees perceive the affordance of their surro

90 uals influenced the behavior and position of flies but had unexpected effects on individual and popul

91 rved by a number of missions that visited or flew by Jupiter over the past several decades.

92 d the role of these animals and their biting flies by testing them for hemotropic mycoplasmas.

93 n-obligate ectoparasitic secondary screwworm flies, C. macellaria, that invade necrotic wound and fee

94 e only virus infection and showed that these flies can be used as a source for experimental infection

95 that causes the 'Minute' phenotype in fruit flies can explain how organisms are able to eliminate th

96 We also show that apple flies can orient in the absence of optic flow by using o

97 y due to the wide range of host plants, good flying capability, and high egg production.

98 RSC-mediated repair extends the lifespan of flies carrying kidney stones.

99 ur results are consistent with a directional fly-casting mechanism for KRAS, in which the membrane-di

100 s in the inhibition pattern enable the fruit fly circuit to respond faster to heading changes while a

101 The screwworm fly, Cochliomyia hominivorax (Coquerel), was successfull

102 hare a common pathway in the early stages of fly colonization but apparently use different mechanisms

103 The skeletal muscle of fruit flies communicates with other organs to prevent the accu

104 Recordings in behaving flies confirmed that motor neurons are typically recruit

105 ormal daytime courtship, which suggests male flies consider nutritional status in deciding whether th

106 In more regular environments, flies continuously modulate speed and orientation, even

107 ses, but high-resolution structures of fruit fly contractile proteins have not been determined.

108 TE libraries: Drosophila melanogaster (fruit fly), Danio rerio (zebrafish), and Oryza sativa (rice).

109 Here, we compare fixed-time to on-the-fly decisions, based on comparing the likelihoods of ant

110 aluated behavioral responses of cabbage root flies [Delia radicum L.

111 In contrast to other Dup15q models, these flies develop seizures that worsen with age.

112 inbred Drosophila melanogaster strains when flies developed in different environments (25 degrees C

113 lta-DFT is highlighted by correcting "on the fly" DFT-based molecular dynamics (MD) simulations of re

114 d on aquatic animals by grabbing prey whilst flying directly above, or floating upon (less likely), t

115 Using the fruit fly Drosophila as an example, we discuss recent work tha

116 (LC) neurons in the optic lobe of the fruit fly Drosophila melanogaster to characterize divergent pr

117 In the vinegar fly Drosophila melanogaster, geosmin is decoded in a rem

118 ory, hygrosensory, and memory systems in the fly Drosophila melanogaster.

119 nal transport of proteins in male and female flies (Drosophila melanogaster).

120 In human (Homo sapiens), fruit fly (Drosophila melanogaster), and yeast (Saccharomyces

121 In this study, we used the fruit fly, Drosophila melanogaster, to investigate how infecti

122 study this fundamental problem, we used the fly, Drosophila melanogaster.

123 Dup15q in Drosophila by elevating levels of fly Dube3a in glial cells using repo-GAL4, not neurons.

124 Communication between male and female fruit flies during courtship is essential for successful matin

125 Strikingly, the proportion of flies dying after M. luteus infection was significantly

126 Cell fate decisions in the fly embryo are rapid: hunchback genes decide in minutes

127 y of antiviral RNAi, and VINR-knockout adult flies exhibit enhanced disease susceptibility to DCV and

128 The few eclosing flies exhibit severe seizures and a reduced lifespan.

129 Although TpnT-CD70-expressing flies exhibited lower resistance to cardiac stress, thei

130 As flies explore a circular arena, their olfactory receptor

131 We therefore engineered flies expressing a genetically encoded Ca(2+) indicator

132 Using flies expressing neural activity indicators, we tracked

133 rescues locomotor activity and ATP levels of flies expressing the key ALS protein, TDP43.

134 nhanced the toxicity of mutant CHMP2B in the fly eye and that Ik2 overexpression suppressed the effec

135 tochondrial activity in mouse adipocytes and fly fat bodies with downregulated PI3K, which were confi

136 we inactivated PI3K by genetic means in the fly fat body and by pharmacological inhibition in mammal

137 Flies fed after appetitive conditioning needed increased

138 es of Chrysomya rufifacies, a monogenic blow fly (females produce female or male offspring, exclusive

139 ns, ranging from control of Golgi structure, fly fertility, and Akt signaling.

140 5 days old were exposed to compounds in the fly food during development.

141 One bird even flew for >5 h without flapping, covering ~172 km.

142 We screened repo>Dube3a flies for approved compounds that can suppress seizures.

143 tionships (termed SampleLASSO), built on-the-fly for each new target sample to be imputed, outperform

144 entified in the scat of the Australian black flying fox (Pteropus alecto), which is the first reprodu

145 Here, we report the black flying fox receptor transporter protein 4 (RTP4) as a po

146 Silencing ventral P-FNs prevented flies from selecting appropriate corrective turns follow

147 In contrast to flies, geosmin is not aversive but mediates egg-laying s

148 Here, we show that the mouse and fly Gsx factors unexpectedly gain DNA binding specificit

149 nstructed from the core members of the fruit fly gut microbiota.

150 We show that tau transgenic flies have an innate biotin deficiency due to tau-mediat

151 he Central Complex in the brain of the fruit fly have identified neurons with activity that tracks th

152 ver a force in order to briefly compress the fly head against a metal surface.

153 at interact with GFP-tagged CLK (GFP-CLK) in fly heads at different times of day.

154 Bulk RNA sequencing from fly heads of the same strain revealed that coexpression

155 transcriptomic and proteomic profiling using fly heads.

156 Feeding flies high PCB 28 concentrations caused lethality.

157 y regulating the protein stability of HIPKs (fly Hipk and human HIPK2), which likely permits the nutr

158 Loss of Cdk8, the fly homolog of CDK19, causes larval lethality, which is

159 found that partial loss function of Ik2, the fly homologue of TBK1 also known as I-kappaB kinase epsi

160 fect of the symbiont following attack of the fly host by the Lh14 strain of wasp to 21% for the Lh-Fr

161 eosmin in a qualitatively similar fashion to flies, i.e., through a single olfactory channel with a h

162 probed the behavior of male and female fruit flies in a circular arena as individuals and within all

163 ignals in the olfactory center of transgenic flies in response to external stimuli including odor and

164 Dispersal limitation for tropical bryophytes flies in the face of traditional assumptions regarding t

165 However, recent detection of these flies in the Florida Keys, and increased risk of introdu

166 altered visual cues used by the cabbage root flies in their host plant selection.

167 A's GeneLab derived from hundreds of samples flown in space to determine transcriptomic, proteomic, m

168 Bumblebees trained to fly in a tunnel were sporadically presented with an obst

169 ears, with between 63 and 100% of individual flies infected.

170 ith antibiotics causes a severe reduction in fly infection success.

171 During Leishmania transmission sand flies inoculate parasites and saliva into the skin of ve

172 rm trends over 25 y but precipitous drops in flying insect numbers on days with low ambient temperatu

173 ence detects and tracks mosquitoes and other flying insects and can apply lethal doses of laser light

174 Flying insects are known to orient themselves over large

175 Deinopids can also intercept flying insects with a "backward strike," a ballistically

176 r, we find that the social distance at which flies interact correlated with the drosophilid phylogeny

177 for age-related regenerative decline in the fly intestine and discusses recent findings that start t

178 complex (BX-C) miRNAs converts virgin female flies into a subjective post-mated behavioral state, nor

179 Memory in fed flies is mediated by the anterior-posterior alpha'/beta'

180 The EGFR-sfGFP fly is an exciting new resource for studying cellular lo

181 Drosophila melanogaster, a fruit fly, is an exquisite model organism to understand neurot

182 r this parasite to establish an infection in flies, it must first colonize the area between the perit

183 In fruit flies, juvenile hormone (JH) induces intestinal stem cel

184 o the difference in target heading angle the fly keeps constant: 0 degrees in azimuth and 23 degrees

185 Strikingly, mice and flies lacking functional autophagy develop early onset p

186 Flies lacking Neuropeptide F display sleep-dependent mem

187 which of the only 10,000 neurons of a fruit fly larva can tip the balance in this trade-off, and ide

188 position site and determine where the female fly lays her eggs.

189 k reveals the functional organization of the fly leg motor system and establishes Drosophila as a tra

190 process proprioceptive information from the fly leg.

191 First, we found that flies, like humans, perceive sustained motion in the sta

192 urrently of more than 2600 plasmids and 1700 fly lines with a focus on targeting kinases, phosphatase

193 We demonstrate that flies make use of features such as foreground segmentati

194 using an actuated dummy as target for freely flying males.

195 will aid in the development of odorant-based fly management strategies.

196 nd mechanical spintronics by allowing on-the-fly manipulation of synthetic spins carried by phonons.

197 Our findings establish the fly mushroom body as a model for homeostatic plasticity

198 pathogens trigger a hypoferremic response in flies, namely, iron withdrawal from the hemolymph and ac

199 y (3D-SIM) and live-cell imaging, we show in fly neural stem cells (neuroblasts) that the mitotic kin

200 itiated caspase activation in differentiated fly neurons.

201 mediated cytotoxicity in mammalian cells and fly neurons.

202 tion in mechanically distinct regions of the fly notum, we find that the ability of cells to properly

203 The New World Screwworm fly (NWS), Cochliomyia hominivorax, is an ectoparasite o

204 issociated ommatidia and in vivo from intact flies of both sexes.

205 r injury and that depriving recently injured flies of sleep slows the removal of both active zones an

206 ficiently low size and weight that it may be flown on a commercial-grade UAV.

207 rs have documented the presence of the fruit fly or Drosophila melanogaster on alcohol-containing foo

208 The DOM-B complex incorporates H2A.V (the fly ortholog of H2A.Z) genome-wide in an ATP-dependent m

209 es we advance a comprehensive model of fruit fly OSNs as a cascade consisting of an odorant transduct

210 Ps and MNP-decorated polymer conjugates were flown over the GMR SV sensor array and detected with a s

211 rmancy in simulated winter conditions, while flies overexpressing tim show an increased incidence of

212 voltage-gated sodium (Na(V)) channel in the fly, para, and identified that Para is enriched at a dis

213 In January 2019, the New Horizons spacecraft flew past one of these objects, the 36-kilometer-long co

214 One possibility is that flies perform frequent comparisons between anterior and

215 e double heterozygous rutabaga/+;octbeta1r/+ flies perform poorly in both aversive and appetitive con

216 We found that the flies perform target tracking in the horizontal plane an

217 dicts a spatio-chromatic receptive field for fly photoreceptor outputs, with a color opponent center

218 Conversely, expression of either fly Piezo or mammalian Piezo1 in these neurons of piezo-

219 light' in both air and water are expected to fly poorly in each fluid relative to single-fluid specia

220 pid development during diapause in the early fly population.

221 This suggests fly populations differ in E. muscae-specific resistance

222 and, if so, how nonhuman animals make on-the-fly predictions during pursuit.

223 tomy of all the primary motor neurons in the fly proboscis and characterize their contributions to it

224 The active ovaries of the fly produce the steroid hormone ecdysone, which stimulat

225 or plumes simultaneously with freely-walking flies, quantifying how behavior is shaped by encounters

226 fluences the probability of attacks and that flying rapidly is effective for escaping pursuing predat

227 n promoters are pervasive in human and fruit fly, reflecting evolutionary conservation.

228 ecomes de-repressed more rapidly in old male flies relative to females, and repeats on the Y chromoso

229 volutionary analyses of mammals, plants, and flies report pervasive rapid evolution of telomere prote

230 ies, anesthesia disrupts rafts and PLD(null) flies resist anesthesia.

231 be used to inflict controlled head injury to flies, resulting in physiological responses that are rem

232 neuronal RNAi-mediated knockdown of Cdk8 in flies results in semi-lethality.

233 ss, we made use of the genetically tractable fly retina, with a focus on the mechanisms that coordina

234 e generated multiple CRISPR knockouts of the fly rrp4 gene.

235 anipulation of homeostatic regulators in the fly's auditory neurons accelerated - or protected agains

236 late both the magnitude and direction of the fly's illusory percept by selectively silencing either T

237 In the absence of ORN activation, the fly's locomotion can be described by a random walk model

238 l, suggesting that mechanisms similar to the fly's may also underlie this illusion in humans.

239 s, acting upstream of core components of the fly's molecular machinery for auditory transduction and

240 be described by a random walk model where a fly's movement is described by its speed and turn-rate (

241 unogenic portions of PdSP15 and LJL143, sand fly salivary proteins demonstrated as potential vaccine

242 fly bites or immunization with defined sand fly salivary proteins was shown to negatively impact inf

243 umoral and cellular immune responses to sand fly salivary proteins.

244 ysis to compare with Old- and New-World sand fly salivary proteins.

245 evolution of the complex wing pattern of the fly Samoaia leonensis We show that the transcription fac

246 f insect disease vectors (mosquitoes, tsetse flies, sandflies) to transmit parasites and disease.

247 ne turtles, pinnipeds, cetaceans, sirenians, flying seabirds and penguins).

248 lisi and other endemic areas with brief sand fly seasons.

249 act tissues, in real time and with an on-the-fly selection of patterns.

250 le propelled micromotors are used as "on-the-fly" sensing platforms in bioassays, using a highly sele

251 In dust-covered flies, sensory inputs change as a result of successful c

252 were fed a low-P high-C diet, revealing that flies shift their macronutrient intake as means of nutri

253 e also involved in taste perception in fruit flies, significantly expanding their scope of action.

254 t during diapause in Rhagoletis pomonella, a fly specialized to feed on fruits of seasonally limited

255 comparative olfactory physiology of the two fly species.

256 s tend to have larger body size, while among flying species, migrants are smaller.

257 Salivary proteins of sand flies, specifically maxadilan and LJM11, have been relat

258 ncreased sleep for memory consolidation, but flies starved after training did not require sleep to fo

259 ngle-cell mRNA sequencing of the same inbred fly strain to map transposon expression in the Drosophil

260 We create a collection of fly strains to individually manipulate every proboscis m

261 protection, including both the chance of the fly surviving attack and the relative fecundity/fertilit

262 We identified 3093 proteins from flies that were induced to express Abeta42 and age-match

263 Bees successfully flew through narrow gaps, even those that were much smal

264 r proteins mediate neuronal targeting in the fly through highly specific protein-protein interactions

265 rom astrocytes, but not from neurons, caused flies to increase their daytime recovery sleep following

266 spects of neural development in animals from flies to mammals, and yet they belong to a large transcr

267 ressing wild-type S1R enhances resistance of flies to oxidative stress.

268 This plasticity in memory circuits enables flies to retain essential information in changing enviro

269 sion is sufficient to disrupt the ability of flies to sense seasonal cues, thereby altering the exten

270 A transcription factor helps young flies to sleep longer by delaying the maturation of a ne

271 hat viewing small spots causes walking fruit flies to stop in their tracks, and identifies the cellul

272 formation mechanism, which is conserved from fly to human, is described here, with exosomes carrying

273 We find that TLS functions 'on the fly' to promote resumption of rapid replication fork rat

274 Our behavioural data suggest that the flies' trajectory changes are a controlled combination o

275 her vision of, and impact on, PCP studies in flies translates to all animal models.

276 nown sugars and sweeteners bind to the Venus Fly Trap domain of T1R2 subunit of the sweet taste heter

277 Further, flies used the timing of odor encounters to modulate the

278 ructures can be modified and analysed on-the-fly using an intuitive toolset.

279 g bites from Lutzomyia longipalpis, the sand fly vector of leishmaniasis, immunize individuals with L

280 n acquiring enough parasites from the tsetse fly vector, the dynamics of the parasite's metabolic rew

281 of flight to realize nanotechnology-enabled flying vehicles without any moving parts in the Earth's

282 al programming language, which allows on-the-fly visualization of binding specificity over a wide ran

283 ngle-cell transcriptional atlas of the adult fly VNC will be a valuable resource for future studies o

284 alter leg motor circuit dynamics so that the fly walks backwards, exemplify the command-type mechanis

285 PCB 28-induced mortality in flies was accompanied by locomotor impairment, a common

286 Despite being the only Na(V) channel in the fly, we show that only 23 +/- 1% of neurons in the embry

287 way-mediated antimicrobial peptides when the flies were challenged with Gram-positive bacteria Microc

288 uteus infection was significantly lower when flies were fed a low-P high-C diet, revealing that flies

289 nsecticide-susceptible horn flies and stable flies were tested topically.

290 wind rightward rotates the compass as if the fly were turning leftward, and vice versa.

291 parasite is transmitted by the bite of sand flies, which inoculate the promastigote forms into the h

292 sound-locating system of the Ormia ochracea fly, which detects sound wavelengths much larger than it

293 omes and sex-determining genes of other blow flies will allow a refined evolutionary understanding of

294 a refined evolutionary understanding of how flies with a typical X/Y heterogametic amphogeny (male a

295 Flies with neuronal expression of IP(3)R(DN) exhibit fli

296 When we probed flies with salient visual stimuli, we found that the act

297 ly convergent circuit architecture, endowing flies with the ability to extract chromatic information

298 region making this region attractive to the flies without emitting any clear directional signals out

299 a conserved regulator of genome stability in flies, worms, zebrafish, and human germ cell tumors.

300 In the fly, wounding stimulates the rapid production of hydroge