ライフサイエンスコーパス: focal dystonia

1 across different phenotypes and genotypes of focal dystonia.

2 imulation in restoring fine motor control in focal dystonia.

3 ere more likely tremulous than patients with focal dystonia.

4 s a fundamental disturbance in patients with focal dystonia.

5 ealthy subjects and in patients with primary focal dystonia.

6 s may explain the clinical symptomatology of focal dystonia.

7 ix of them had segmental dystonia and 59 had focal dystonia.

8 o the role of muscle spindle Ia afferents in focal dystonia.

9 (ICD) is the most common form of adult-onset focal dystonia.

10 lvement in the pathophysiology of idiopathic focal dystonia.

11 (linked or not linked to 9q34) and sporadic focal dystonia.

12 15 proteins were associated with adult-onset focal dystonia.

13 1808Ser) presented with isolated adult-onset focal dystonia.

14 y prolonged ocSSRT is associated with PD and focal dystonia.

15 motor manifestations of isolated adult-onset focal dystonias.

16 ortex are differentially affected in primary focal dystonias.

17 may play a central role in these particular focal dystonias.

18 r blepharospasm, hemifacial spasm, and other focal dystonias.

19 he possibility of DDP mutation in women with focal dystonias.

20 o further investigate genetic factors in the focal dystonias.

21 as motor pathophysiology to fully understand focal dystonias.

22 een increasingly recognized in patients with focal dystonias.

23 teral motor cortices of 20 pianists (10 with focal dystonia, 10 healthy controls) were electrically s

24 ients with three different forms of isolated focal dystonia and 220 healthy controls.

25 athophysiological role for the phenomenon in focal dystonia and divergent pathophysiological processe

26 g deficits in neurological diseases, such as focal dystonia and Parkinson's disease, and possibly pro

27 ce of a mitochondrial deficiency in sporadic focal dystonia and provide a biochemical dimension to th

28 one in putamen in 21 patients with these two focal dystonias and compared the findings with those fro

29 t is often genetic in origin, to adult-onset focal dystonias and rarer forms of secondary dystonias,

30 ocial anxiety severity vary by onset site of focal dystonia, and this variation is not explained by d

31 The adult-onset focal dystonias are characterized by over-active muscles

32 e best treatment option for the treatment of focal dystonias: blepharospasm, hemifacial spasm, and ap

33 tients from northern Germany who had primary focal dystonia, both for the GAG deletion in the DYT1 ge

34 um between several chromosome 18 markers and focal dystonia, both in sporadic patients from northern

35 c complex I defect in patients with sporadic focal dystonia but could not find any abnormality in pat

36 Isolated focal dystonia can spread to muscles beyond the initiall

37 Spasmodic dysphonia is a primary focal dystonia characterized by involuntary spasms in th

38 nical phenotype of genetically proven DRD to focal dystonia, dystonia with relapsing and remitting co

39 two new dystonia genes, one for adult-onset focal dystonia (DYT7) and one for a mixed dystonia pheno

40 include idiopathic torsion dystonia (DYT1), focal dystonias (DYT7) and mixed dystonias (DYT6 and DYT

41 features that can be seen in parkin disease: focal dystonia; early instability; freezing; festination

42 Preliminary studies of patients with focal dystonia, epileptic seizures, and auditory halluci

43 Patients with isolated focal dystonia evaluated within 5 years from symptom ons

44 significantly increased in both hands in the focal dystonia groups (thresholds were similar for each

45 ion included the Fahn dystonia scale for the focal dystonia groups and the Marsden-Burke-Fahn scale f

46 igated the pathophysiology of two idiopathic focal dystonias: hand cramp with excessive cocontraction

47 Initial body region affected in isolated focal dystonia has differential risk and patterns of spr

48 Patients with Parkinson's disease and focal dystonia have difficulty in generating and prevent

49 Early studies in focal dystonias have pointed to segregated changes in br

50 er, these results suggest that most cases of focal dystonia in patients of northern German or central

51 e existence of a founder mutation underlying focal dystonia in this population.

52 Isolated focal dystonia is a debilitating movement disorder of un

53 Isolated focal dystonia is a neurological disorder that manifests

54 l healthy controls (N = 49) with adult-onset focal dystonia (N = 143) consisting of specific subpopul

55 l hand somatosensory area of 6 patients with focal dystonia of the hand, we found an abnormality of t

56 Spasmodic dysphonia (SD) is an incurable focal dystonia of the larynx that impairs speech and com

57 ged in patients with Parkinson's disease and focal dystonia (one-way ANOVA p < 0.001).

58 e decreased in specific brain regions of the focal dystonia patients compared to normal controls.

59 d in recently diagnosed adult-onset isolated focal dystonia patients.

60 own about its origins; it is classified as a focal dystonia secondary to an unknown neurobiological m

61 ed has increased greatly to include numerous focal dystonias, spasticity, tremors, cosmetic applicati

62 ncy in platelets from patients with sporadic focal dystonia suggests that a defect of energy metaboli

63 ction of linkage for one form of adult-onset focal dystonia to chromosome 18p (DYT7) in a family from

64 architecture of the functional connectome in focal dystonia was analyzed in a large population of pat

65 To evaluate the role of these loci in focal dystonia, we tested 85 patients from northern Germ

66 Task-specific dystonia is a form of isolated focal dystonia with the peculiarity of being displayed o