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1 ortions of bacteria distributed across fewer foci.
2 r corridors serve as year-round transmission foci.
3 tic plasticity in the emergence of epileptic foci.
4 oining, and decreased the formation of Rad51 foci.
5 antial concordance for margins and echogenic foci.
6 of gammaH2A.X and 53BP1 at mitochondrial DNA foci.
7 patients (65 years +/- 17; 70 men) with 146 foci.
8 expressed in these cells, UdgX tends to form foci.
9 regate-like assemblies visualized as nuclear foci.
10 spectively for hyperattenuating intracranial foci.
11 , resulting in formation of discrete nuclear foci.
12 phically and morphologically distinct tumour foci.
13 se separation of DDR factors in the shape of foci.
14 nduces phosphorylation of gammaH2AX-positive foci.
15 portions of bacteria distributed across many foci.
16 esolve ionizing radiation-induced DNA damage foci.
17 that miR-144-3p is expressed in fibroblastic foci.
18 level of regulation of 53BP1 outside repair foci.
19 ction and accumulation of CtIP at IR-induced foci.
20 to the piRNA clusters and forming the piRNA foci.
21 f cleaved caspase-3, and increased gammaH2AX foci.
22 three factors colocalize in heterochromatic foci.
23 e cells are concentrated within fibroblastic foci.
24 are essential for formation of these repair foci.
25 ation, causes a significant increase in UdgX foci.
26 y and the accumulation of intranuclear dsRNA foci.
27 halomalacia, corresponding to known ischemic foci.
28 atic activity (rnhAK60E) eliminates RNase HI foci.
29 ng complexes normally concentrate in nuclear foci.
30 re they generated vasculogenic and hemogenic foci.
31 nts, NUCKS1 controls the resolution of RAD54 foci.
32 ly differentiated by the number of bacterial foci.
33 larger Ser2p CTD-modified RNA polymerase II foci.
34 volving the cortex and classical subcortical foci, 2) a preponderance of regional GMV sex differences
35 l of 287 lesions identified: 37 prostate bed foci, 208 lesions in lymph nodes, and 42 in distant site
36 ying a total of 287 lesions: 37 prostate bed foci, 208 lymph nodes, and 42 bone/organ distant sites;
39 r reader 1 (P = .019) and from 46% (19 of 41 foci; 95% CI: 31%, 62%) to 85% (35 of 41 foci; 95% CI: 7
40 d as "certain") increased from 71% (29 of 41 foci; 95% CI: 57%, 85%) to 90% (37 of 41 foci; 95% CI: 8
42 reader accuracy from 90% (reader 1, 37 of 41 foci; 95% CI: 81%, 99%) and 93% (reader 2, 38 of 41 foci
43 41 foci; 95% CI: 57%, 85%) to 90% (37 of 41 foci; 95% CI: 81%, 99%) for reader 1 (P = .019) and from
44 5% CI: 81%, 99%) and 93% (reader 2, 38 of 41 foci; 95% CI: 85%, 100%) to 100% (both readers, 41 of 41
46 accuracies for the test set of 88% (36 of 41 foci; 95% confidence interval [CI]: 78%, 98%) and 95% (3
47 ment of TOPBP1, ATR and CHK1 to 53BP1 damage foci, abrogating cell cycle arrest and permitting progre
48 IMR-1 also localizes to distinct subcellular foci adjacent to P granules and Mutator foci, two phase-
49 d system features multiple confocal scanning foci, affording 1.5 micron depth-resolution and millisec
51 found that EML4 was distributed as punctate foci along the microtubule lattice in interphase but exh
53 repair of double-strand breaks coalesce into foci, although the significance and mechanisms giving ri
56 tion of MBNL1 splicing factor by nuclear RNA foci and consequently MBNL1 functional loss, responsible
57 DMPK mRNAs are toxic, present in nuclear RNA foci and correlated with a plethora of RNA splicing defe
58 (4)C(2) repeats and the levels of repeat RNA foci and dipeptide repeat proteins in cortical neurons d
62 ngs uncovered the nature of persistent PARP1 foci and identified NAD+ interacting residues involved i
64 pon damage, HNRNPD re-localized to gammaH2Ax foci and its silencing impaired CHK1 S345 phosphorylatio
65 bacteria determine the frontier of infection foci and may promote bacterial infection persistence in
66 lation and diminished formation of gammaH2AX foci and of 53BP1-containing telomere dysfunction-induce
67 rance of RecA foci, the appearance of pol IV foci and RecA-pol IV colocalization are all dependent on
68 HPNE cells that overexpressed KDM3A formed foci and spheres in culture and formed tumors and metast
73 in rec8 that recruit DSB-associated protein foci and undergo synapsis, which is followed by chromoso
74 co-localized with DUX4-induced nuclear dsRNA foci and with intranuclear aggregation of EIF4A3 and ADA
75 to regulate RAD51 recruitment to DNA repair foci and, secondly, during replication fork restart foll
76 tion, echogenicity, shape, margin, echogenic foci), and a genetic AI algorithm was applied to a train
77 defective leukocyte recruitment to infection foci, and 3) production of anti-inflammatory effectors I
80 res including drusen volume, hyperreflective foci, and OCT-reflective drusen substructures independen
81 ns and substantial concordance for echogenic foci, and the third radiologist had nearly perfect conco
82 n RAP80 recruits BRCA1 to postdamage nuclear foci, and these chromatin structures then restrict the a
86 Thus, we propose that the persistent PARP1 foci are formed by different PARP1 molecules that are co
87 rsion mutations and an ability to form RAD51 foci are frequently not observed in models of acquired P
89 ssibility, and compaction of heterochromatin foci are independent of HP1; (3) heterochromatin foci la
93 that comprise pericentriolar material-these foci are structures with a microtubule-nucleating capaci
94 rphologically, COL3-CD167a-driven metastatic foci are uniquely distinct from typical lung alveolar me
95 of accumulation and disappearance of protein foci are used to monitor DNA damage and repair kinetics.
98 le-strand breaks, detected by proxy as RAD51 foci at leptotene, but only ~2.3% of these sites mature
99 umor cells often contain abundant DNA damage foci at telomeres and rely on the alternative lengthenin
102 lacking downstream regions are gathered into foci at the nuclear envelope, but Yb bodies are not asse
103 n of these factors causes a reduction in DDR foci both in vivo and in an in vitro system that reconst
104 Tryptic peptides are generated from tissue foci by applying small volume droplets (~250 pL) of enzy
105 r MBNL1, which is sequestered in nuclear RNA foci by C(C)UG microsatellite expansions in myotonic dys
106 were then spaced within 3 min into compacted foci by myosin motors or more slowly (30 min) aggregated
107 studies have revealed that individual tumour foci can arise as clonally distinct lesions with no shar
108 coccus aureus siderophores across infectious foci, challenging the paradigm that the vertebrate host
109 d stress, the biophysical properties of HSF1 foci changed; small, fluid condensates enlarged into ind
112 These results reveal that XRCC1-contaning foci constitute newly recognized PML-like nuclear bodies
114 copy and single-cell analysis, we found that foci dissolution rather than formation promoted HSF1 act
115 g; presence of hyper-reflective intraretinal foci; dome-shaped pigment epithelium detachment (PED); h
119 of the Smc5-Smc6 genome stability complex in foci during replication stress and for activation of the
120 formation by a classic promoter resulting in foci, each of which encode a unique genetic profile.
121 ence databases were developed with different foci, either prioritizing accuracy (low number of false
122 penetration of the cell membrane at discrete foci, followed by gradual loss of turgor, subsequent acc
123 es does not affect formation of 53BP1 or ATM foci following DNA damage, but abolishes recruitment of
124 umulation, as marked by increased gamma-H2AX foci following induction of double-stranded breaks.
127 haracterized multiple cycles of 53BP1 repair foci formation and dissolution, with the first cycle tak
129 te of PALB2, mutations in which reduce RAD51 foci formation and the overall HDR efficiency in cells b
136 ormation or dsRNA processing impairs CTD Y1P foci formation, attenuates DART synthesis and delays rec
137 sion of the mutant DMPK 3'UTR results in RNA foci formation, MBNL1 sequestration, splicing defects, m
140 constriction: medioapical Patronin (CAMSAP) foci formed by actomyosin contraction organized an apica
141 bination nodules and a reduced number of the foci formed by the recombinases RAD51/DMC1, thus leading
144 in turn leads to sequestration of infectious foci from innate immune effectors and systemically deliv
145 inal cyst and the numbers of hyperreflective foci from OCT images and SSPiM from OCTA images were com
147 opment of CNV: intraretinal hyper-reflective foci had an HR of 11.58 (95% confidence interval [CI]: 1
148 nitrogen starvation, we demonstrate that Hfq foci have a role in the adaptive response of E. coli to
149 nce, location, and amount of hyperreflective foci (HF); (5) disorganization of retinal inner layers (
151 al pigment epithelium (RPE), hyperreflective foci (HRF), fibrovascular pigment epithelium detachment
152 neous fibrosis characterized by fibroblastic foci, hyperplastic AT2 cells, and increased susceptibili
156 The SSB-IDL fusions form detectible SSB foci in cells with frequencies mirroring previously exam
161 amentous structures capable of bridging MDC1 foci in mitosis, indicating that MDC1-TOPBP1 complexes t
162 ncrease the probability of detecting seizure foci in patients and facilitate the study of brain disea
165 ing PBG98-VP1-TC infection, had green or red foci in the cytoplasm, respectively, that colocalized wi
166 tonigrin treated cells exhibit compacted DNA foci in the nucleus that co-localize with Heterochromati
168 tionally, wild-type Cas9 induced fewer 53BP1 foci in TP53+/+ cells compared to TP53-/- cells and DD-C
170 tiFish for rapid quantitation of fluorescent foci in zebrafish larvae, to support infection research
172 clonogenic survival decreased and gammaH2AX foci increased for cells expressing high levels of somat
173 ibution, and number of arterial inflammatory foci (increased (18)F-FDG uptake) and plaques with or wi
174 ed neutrophil infiltration at the infectious foci, increased bacteremia, systemic inflammatory respon
175 d the tardy exchange of ATM-KD at DNA damage foci, indicating that PRD coordinates ATM activation wit
178 s a highly dynamic pattern composed of actin foci interspersed with linear filaments and myosin IIa.
179 on of silenced and condensed heterochromatin foci involves enrichment of heterochromatin protein 1 (H
180 n NHEJ, as indicated by decreased IR-induced foci (IRIF) formation by pS2056-, pT2609-DNA-PKcs, pS177
183 n- and etoposide-induced gammaH2AX and 53BP1 foci, it markedly delays their resolution, indicating a
184 tribution from the cytoplasm into subnuclear foci known as photobodies (PBs), which dissipate after P
185 are independent of HP1; (3) heterochromatin foci lack a separated liquid HP1 pool; and (4) heterochr
186 We find that alpha-satellite RNA-smFISH foci levels vary across cell lines and over the cell cyc
188 hat transiently expressed PWO1 proteins form foci located partially at the subnuclear periphery.
192 frameworks also prioritize certain research foci, motivate the use diverse empirical approaches and,
194 sed protein (Tex)14 showed ~59% reduction in foci number and size, without any change in Tex14 mRNA l
195 A images was associated with hyperreflective foci numbers (P = 0.038) and mean ODR of the intraretina
196 hibition reduced the number of S. pneumoniae foci observed in hearts of acutely infected mice and ser
199 describe the generation of gastrulation-like foci of cells within micropatterned colonies of pluripot
201 n tumors, spleen, liver, and kidney revealed foci of EBV-infected cells in perivascular regions in cl
202 Four other animals presented with multiple foci of ectopic calcification within the walls of the gr
206 performance in the differentiation of small foci of intracranial hemorrhage from calcium and improve
209 ded; beta-catenin-mutated HCAs and HCAs with foci of malignancy were considered to be at risk for pro
213 ical failure after radical prostatectomy had foci of suggestive uptake, even at low serum PSA levels.
214 nd-like splicing regulator 1, elimination of foci of toxic RNA, reversal of splicing biomarkers and a
215 e-deficient mutants led to increased SUMO2/3 foci on chromosomes, suggesting that the reduction of SU
220 and P = 0.03, respectively), hyperreflective foci (P < 0.001 and P = 0.045, respectively), OCT-reflec
221 ults also showed a decrease of DnaB helicase foci per cell after UV, consistent with the disassembly
222 60 tissue samples, scoring for the number of foci per cell of the crossover-associated protein MLH1.
224 ence standard, a CNN was developed to detect foci positive for (18)F-FDG uptake, predict the anatomic
226 uses formation of RNA polymerase II (RNAPII) foci, predominantly phosphorylated at carboxy-terminal d
230 These findings indicate that heterochromatin foci resemble collapsed polymer globules that are percol
236 normal DSB positioning, but persistent DMC1 foci, severe DSB repair and synapsis defects, and downst
237 peak acoustic powers 0.9-3.8 kW, sonication foci spaced 1-1.5 mm apart in a rectangular grid with 5-
238 t binding of acetyl-reader proteins, H3K27ac foci still appeared but RNAP2 Ser2ph and miR-430 morphol
239 miR-430 morpholino were not concentrated in foci, suggesting that H3K27ac precedes active transcript
242 patients had extensive hyperautofluorescent foci surrounding an area of central atrophy on SW-AF ima
244 18-fluorodeoxyglucose PET uptake patterns in foci suspicious and nonsuspicious for cancer in patients
245 acterizations, we identified the replication foci targeting sequence (RFTS) domain of maintenance DNA
246 sed by dominant mutations in the replication foci targeting sequence (RFTS) of the DNA methyltransfer
249 sulted in the formation of small replication foci that colocalize with replication proteins but are d
251 ased levels of TRIM37 block the formation of foci that comprise pericentriolar material-these foci ar
252 ion machinery is concentrated within ~200-nm foci that contact specialized patches of endoplasmic ret
253 rial dysfunction, EOL-1 is concentrated into foci that depend on the transcription of mitochondrial R
254 determining hypermetabolic (18)F-FDG PET/CT foci that were suspicious for cancer versus nonsuspiciou
257 of the SOS response, the appearance of RecA foci, the appearance of pol IV foci and RecA-pol IV colo
258 ns and substantial concordance for echogenic foci; the second radiologist had nearly perfect concorda
260 3BP1-containing telomere dysfunction-induced foci (TIFs), indicating defects in DNA damage checkpoint
261 53BP1-positive telomere dysfunction-induced foci (TIFs), indicating that DNA double-strand breaks oc
263 rough different stages ranging from isolated foci to confluent sclerotic zones which-seemingly-constr
265 ts of bacterial load and number of bacterial foci to include measures for dissemination of infection.
267 ular foci adjacent to P granules and Mutator foci, two phase-separated condensates that are the sites
270 at the FBL17 protein is recruited at nuclear foci upon double-strand break induction and colocalizes
273 ells with detectable NR2F2 and NR2C2 nuclear foci varies considerably between ALT+ cell lines and doe
274 by 18 mo of age, the number of hyperplastic foci was reduced, the ducts of the VP and MG became atro
275 The volume of intraretinal hyper-reflective foci was significantly larger in eyes with hyper-transmi
276 n of cell death, and occurrence of gammaH2AX foci, we found that fbl17 mutants are hypersensitive to
282 photoreceptors and scattered hyperreflective foci were correlated with changes in the retinal pigment
288 n supported lipid bilayers and forms dynamic foci when expressed heterologously in live yeast and M.
289 DNA damage, and the experimental readout of foci when immunocytochemistry coupled to 2D fluorescence
290 nuclear medicine experts manually delineated foci with increased (18)F-FDG uptake, specified the anat
294 (47.7%), and three with restricted diffusion foci within the corpus callosum consistent with cytotoxi
295 ion was required for AHL10 complexes to form foci within the nucleoplasm, suggesting that S314 phosph
297 roscopy provides the visualization of tissue foci without the need for chemical stains or the use of
298 h often contain only sparse antigen-positive foci yet display areas of focal necrosis and cellular lo
299 ings, e.g. contributing to the saturation of foci yields scored at 30 minutes after exposure with inc
300 damage can be assessed measuring DNA damage foci yields, only provided that artefacts related to the