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1 loblastic anemia observed in vitamin B12 and folate deficiency.
2 omocysteine to form methionine, as occurs in folate deficiency.
3 e beta (beta-pol) is observed in response to folate deficiency.
4 le-strand break repair gene was activated by folate deficiency.
5 h abnormal hepatic methionine metabolism and folate deficiency.
6 rhomocysteinemic mice even in the absence of folate deficiency.
7 fferences in the prevalence of cobalamin and folate deficiency.
8 n due to the mutation was absent in men with folate deficiency.
9 ntly associated with lower anemia, iron, and folate deficiency.
10 f folate stress and the healthcare impact of folate deficiency.
11 thogenesis of human diseases associated with folate deficiency.
12 nd expressivity were exacerbated by maternal folate deficiency.
13 s indicated that they had metabolic signs of folate deficiency.
14 expense of homocysteine remethylation during folate deficiency.
15 previously described as a model for systemic folate deficiency.
16 nd p-Tau was exacerbated in cells exposed to folate deficiency.
17 hnRNP-E1 was a plausible candidate sensor of folate deficiency.
18 growth by creating an intracellular state of folate deficiency.
19 ally relevant, sensitive, cellular sensor of folate deficiency.
20   No patients developed iron, vitamin B12 or folate deficiency.
21 ct of the polymorphism on FOCM is greater in folate deficiency.
22 ay be the result of vitamin B-12 rather than folate deficiency.
23 ic acid alone or folic acid + iron decreased folate deficiency.
24                          Ethanol feeding and folate deficiency acted together to decrease the liver S
25                                              Folate deficiency activated base and nucleotide excision
26 ce in the number of participants who had RBC folate deficiency after each treatment (P = 0.059).
27 uggest that, in addition to vitamin B-12 and folate deficiencies alone, there may be adverse birth ou
28                                     Maternal folate deficiency alone is sufficient to induce NTDs in
29                                              Folate deficiency also caused a decrease in phosphorylat
30                                              Folate deficiency also increased the CD4(+) to CD8(+) ra
31                           Abrupt reversal of folate deficiency also led to a rapid parallel reduction
32                     These data indicate that folate deficiency alters the balance and coordination of
33 ew aimed to review the available evidence on folate deficiency among women with epilepsy, particularl
34  the effects of vitamin B12, vitamin B6, and folate deficiencies and explain why homocysteine is not
35 chastic noise in FOCM that results from both folate deficiency and a common variant in the methylenet
36  serum folate levels, and the prevalences of folate deficiency and anemia were not associated with de
37 y anemia was defined as the presence of both folate deficiency and anemia.
38 r intermediates, these data demonstrate that folate deficiency and beta-pol haploinsufficiency intera
39      One-carbon metabolism is compromised by folate deficiency and common genetic polymorphisms.
40              Although FRs are upregulated in folate deficiency and downregulated following folate rep
41              We determined the prevalence of folate deficiency and folate-deficiency anemia within a
42 -and also to its side effects, which include folate deficiency and gastrointestinal upset.
43 ic acid, which has reduced the prevalence of folate deficiency and hyperhomocysteinemia.
44                                              Folate deficiency and hypomethylation have been implicat
45        Moreover, RS could be used to predict folate deficiency and identify the sex of the animals.
46 ship between hyperhomocysteinemia induced by folate deficiency and premature hearing loss involves im
47 logical and experimental studies have linked folate deficiency and resultant increased homocysteine l
48  hyperhomocysteinemic mice in the absence of folate deficiency and that levels of SAM and SAH are alt
49  different genotoxic mechanisms arising from folate deficiency and the impact on genome stability.
50 e the genetic and epigenetic consequences of folate deficiency and to investigate whether impairment
51  anemia and/or pancytopenia, severe cerebral folate deficiency, and cerebral tetrahydrobiopterin defi
52 levated plasma total homocysteine (tHcy) and folate deficiency, and have shown that folate supplement
53 ine, for detection of either vitamin B-12 or folate deficiency, and methylmalonic acid for detection
54 ome and is the most accurate animal model of folate deficiency anemia described to date that closely
55 dge, no one has determined the prevalence of folate-deficiency anemia after fortification.
56  folic acid fortification, the prevalence of folate-deficiency anemia is nearly nonexistent in a comm
57                   Overall, the prevalence of folate-deficiency anemia was <0.1% (1 of 1546 subjects).
58                                              Folate-deficiency anemia was defined as the presence of
59 ined the prevalence of folate deficiency and folate-deficiency anemia within a sample of the Reasons
60                       Notably, the effect of folate deficiency appears more deleterious in female emb
61                        In laboratory models, folate deficiency appears to induce p53 mutation.
62                                Correction of folate deficiency approximately doubles the efficacy of
63                                              Folate deficiencies are prevalent in countries with insu
64 n American women and elevated serum tHcy and folate deficiency are more prevalent in elderly African
65                                The causes of folate deficiency are multifactorial, and awareness, ear
66 h metabolically significant vitamin B(12) or folate deficiency are particularly prone to depression.
67                                              Folate deficiency around the time of Friend virus-infect
68 animal studies to human pregnancy shows that folate deficiency as well as one-time exposure to enviro
69 ic strategies for conditions associated with folate deficiency, as well as cancer.
70 hat thymidylate biosynthesis is preserved in folate deficiency at the expense of homocysteine remethy
71  Vangl2 and provide a new mechanism by which folate deficiency can contribute to the etiology of NTDs
72                                              Folate deficiency can occur because dietary folate intak
73 are unable to synthesize folate de novo, and folate deficiency can result from several causes, includ
74 e uptake experiments demonstrated a systemic folate deficiency caused by disruption of PCFT-mediated
75                    Though both radiation and folate deficiency caused DNA breaks, they affected the e
76              The nucleotide imbalance due to folate deficiency causes cell cycle arrest in the S phas
77                                              Folate deficiency causes massive incorporation of uracil
78                         Furthermore, because folate deficiency causes neural tube defects, some birth
79                                     Cerebral folate deficiency (CFD) syndrome is a neurodevelopmental
80                                    Levels of folate deficiency commonly found resulted in effects sim
81                                              Folate deficiency contribute to neural tube defects (NTD
82  nutritional status of the subjects, because folate deficiency could confound the effects of low-dose
83                           Both radiation and folate deficiency decreased cell proliferation and induc
84                                              Folate deficiency decreased liver folate levels and incr
85                                              Folate deficiency decreases thymidylate synthesis from d
86        Red blood cell folate is measured for folate deficiency diagnosis, because it reflects the lon
87                  These results indicate that folate deficiency did not exert its enhancement of leuke
88 beta-pol-haploinsufficient mice subjected to folate deficiency displayed additional increases in DNA
89 gether, these findings strongly suggest that folate deficiency disrupts the BBB function by targeting
90                                              Folate deficiency does not cause NTDs in wild-type mice,
91                                              Folate deficiency during pregnancy has been associated w
92                                  KEY POINTS: Folate deficiency during pregnancy is associated with re
93                                              Folate deficiency, either by diet or drug, increases pla
94 ns may therefore be a means by which dietary folate deficiency enhances carcinogenesis.
95                                              Folate deficiency enhances colorectal carcinogenesis in
96                                  In summary, folate deficiency enhances perturbations in hepatic meth
97  women, we also calculated the prevalence of folate deficiency (erythrocyte folate < 317.2 nmol/L) wi
98 ely, knockdown of either protein accelerates folate deficiency-evoked cell toxicity.
99 tudies demonstrated that Aldh1l1, similar to folate deficiency, evokes metabolic stress and causes ap
100                                              Folate deficiency (FD) has been shown to induce DNA dama
101 istidine degradation pathway and a marker of folate deficiency, formiminoglutamate, was increased mor
102                                     However, folate deficiency had no additional effect on the DNA mu
103                                              Folate deficiency has been associated with an increased
104                                              Folate deficiency has been associated with many adverse
105                                              Folate deficiency has been associated with uracil misinc
106                                              Folate deficiency has been shown to be associated with i
107 ified with folic acid, and the prevalence of folate deficiency has decreased dramatically.
108                                              Folate deficiency has serious consequences for the fetus
109                                     Cellular folate deficiency impairs one-carbon metabolism, resulti
110                           Dietary or genetic folate deficiency impairs this cycle, leading to develop
111                                        Thus, folate deficiency impedes tumor growth rate, but supplem
112                             Vitamin B-12 and folate deficiencies in women and children have important
113 ing population prevalence of vitamin B-12 or folate deficiencies in WRA or PSC.
114       HHcy was related to vitamin B12 and/or folate deficiency in 55% (87/165), mutations in one or m
115 ee-months was effective in reducing iron and folate deficiency in adolescent girls.
116        In contrast with previous evidence of folate deficiency in adult IBD patients, our data indica
117 cumulation and the apoptosis were induced by folate deficiency in erythroblasts from p53 null mice.
118                                              Folate deficiency in fetal life is strongly associated w
119 s is one of several factors used to diagnose folate deficiency in humans.
120 cancer and cognitive defects associated with folate deficiency in humans.
121 ors and MTHFD1 protein in the nucleus during folate deficiency in mouse liver and human cell lines ac
122                                              Folate deficiency in PHT cells caused inhibition of mTOR
123 conjunction with a low-folate diet prevented folate deficiency in pregnant women.
124       We investigated the effect of isolated folate deficiency in rats on DNA methylation and DNA str
125 rk is needed to understand the mechanisms of folate deficiency in women with epilepsy and to develop
126                                              Folate deficiency in women with epilepsy may reflect dis
127  progress recently achieved in understanding folate deficiency in women with epilepsy, there are stil
128                          Common triggers for folate deficiency include poor dietary intake, inadequat
129                   All patients with cerebral folate deficiency, including one with low CSF levels of
130                             In some studies, folate deficiency increased the development and growth o
131                                       Hence, folate deficiency increases the risk of NTDs in genetica
132                                              Folate deficiency induced a pronounced global increase i
133  progenitor cells is a molecular etiology to folate deficiency-induced anemia.
134                                              Folate deficiency induces DNA breaks and may alter cellu
135                       Our data indicate that folate deficiency induces DNA strand breaks and hypometh
136 e was not associated with changes in iron or folate deficiency, inflammation, or high blood lead.
137                       The mechanism by which folate deficiency influences carcinogenesis is not well
138          To elucidate the mechanism by which folate deficiency influences carcinogenicity, we have an
139                                     Maternal folate deficiency inhibited placental mTORC1 and mTORC2
140 ate sensor in vivo in mice and that maternal folate deficiency inhibits placental mTOR signaling and
141 dicate that the MTHFR C677T polymorphism and folate deficiency interact to increase the stochastic be
142                            As a consequence, folate deficiency is a global problem.
143 ers, and seeds are poor in this vitamin, and folate deficiency is a worldwide problem.
144                        A metabolic effect of folate deficiency is an elevation of blood homocysteine.
145                                              Folate deficiency is associated with a number of develop
146     Folic acid is an essential nutrient, and folate deficiency is associated with a variety of disord
147                        The data suggest that folate deficiency is associated with gene-specific methy
148                                              Folate deficiency is associated with increased risks of
149                                              Folate deficiency is common among women with epilepsy.
150                    Many reports suggest that folate deficiency is common among women with epilepsy.
151 l component of many metabolic processes, and folate deficiency is known to cause various disorders.
152                                              Folate deficiency is linked to many diseases, some of wh
153                                     Maternal folate deficiency is linked to restricted fetal growth,
154                                        While folate deficiency is not common in the United States due
155                                              Folate deficiency is typically indicated when circulatin
156 significant folate for accurately diagnosing folate deficiency, is 5-methyltetrahydrofolic acid (5 MT
157 r folates that can act as vitamins to rescue folate deficiency lack this germ cell stimulatory activi
158                                              Folate deficiency leads to increased dUMP/dTMP ratios an
159                                              Folate deficiency leads to neural tube defects and other
160                        Because physiological folate deficiency led to the intracellular homocysteinyl
161                                              Folate deficiency (&lt;11 nmol/L) was associated with 75% a
162         No participants presented with serum folate deficiency (&lt;7 nmol/L).
163                                              Folate deficiency may accelerate or promote ALD by incre
164                                Correction of folate deficiency may decrease the frequency of intragen
165                     Our results suggest that folate deficiency may enhance the development of acute l
166         Clinical studies have indicated that folate deficiency may enhance the development of various
167                                       During folate deficiency mouse liver MTHFD1 levels are enriched
168                                     Cerebral folate deficiency (N=12) was most common, with normal se
169  rates of folate catabolism and simultaneous folate deficiency occur in several physiological states,
170 cinogenicity, we have analyzed the effect of folate deficiency on base excision repair (BER), the pat
171 e of this study was to address the impact of folate deficiency on hearing loss and to examine the und
172  investigated the functional consequences of folate deficiency on HPV16 in immortalized HPV16-harbori
173 n animal studies that examined the effect of folate deficiency on malignancies, conflicting results h
174                   Examples are the effect of folate deficiency on neural tube development during earl
175  thymidine, or deoxyuridine with and without folate deficiency on NTD incidence in the Shmt1 mouse mo
176          We examined the effect of transient folate deficiency on the development of leukemia in mice
177  specific effects of ethanol with or without folate deficiency on the expressions and activities of h
178 ols, and experimental evidence suggests that folate deficiency or focal administration of homocystein
179 ethylation, particularly in populations with folate deficiency or hyperhomocysteinemia or both, may l
180                                        Acute folate deficiency or incubation of CCRF-CEM with AICAr-r
181              Although < 0.5% of children had folate deficiency or low vitamin B-12 status, the consum
182 th CCD had ferritin deficiency (P = .007) or folate deficiency (P = .003) than patients with USCD or
183                   In the absence of clinical folate deficiency, periconceptional supplementation with
184                            The prevalence of folate deficiency (plasma folate </= 6.8 nmol/L) in the
185  sensing of varying degrees of physiological folate deficiency, prior to adaptive optimization of cel
186                            The prevalence of folate deficiency (RBC folate <or= 160 ng/mL) was <1%.
187                                              Folate deficiency reduced proliferation of T lymphocytes
188 ciated with fetal abnormalities and cerebral folate deficiency-related developmental disorders.
189 ngitudinal follow-up showed that gestational folate deficiency results in behavioral changes-an anxie
190                           Ethanol feeding or folate deficiency, separately or in combination, decreas
191                                              Folate deficiency (serum folate <11.4 nmol/L, tHcy >13.9
192 ne, which accumulates intracellularly during folate deficiency, stimulated interactions between heter
193 blished "folate trap," creating a functional folate deficiency that may contribute to the metabolic p
194 nosis and management of iron, cobalamin, and folate deficiencies, the most frequent causes of anemia
195                                              Folate deficiency, therefore, could contribute to abnorm
196 e for beta-pol in the phenotype expressed by folate deficiency, these data are also consistent with t
197 pidemiologic studies have linked nutritional folate deficiency to an increased risk of cancer, but re
198 rradiated or cultured at different levels of folate deficiency to assess cell proliferation, apoptosi
199 umented the resulting decrease in anemia and folate deficiency, to our knowledge, no one has determin
200 trategies are currently implemented to fight folate deficiency, up until now, all of them have their
201 ne synthase reaction, results in a secondary folate deficiency via the accumulation of folate as 5-me
202                                              Folate deficiency was defined as a serum folate concentr
203                           A wide response to folate deficiency was seen in cells from different donor
204 ith anemia, but malaria and vitamin B-12 and folate deficiencies were not.The contribution of iron de
205            Children of mothers with prenatal folate deficiency were at higher risk of emotional probl
206 ons.There was a very low prevalence (<1%) of folate deficiency when serum (<7 nmol/L) and RBC (<305 n
207 finity throughout the range of physiological folate deficiency, which correlated with a proportionate
208 ive patients were subsequently found to have folate deficiency, which left 18 evaluable patients in t
209                                              Folate deficiency with anemia declined significantly in
210  in a micropig model where combining dietary folate deficiency with chronic ethanol feeding produced
211                               Association of folate deficiency with neural tube defects and impact of

 
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