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1 pendent on its function as a plasma membrane folate transporter.
2 plex 1 and 2 and requires the proton-coupled folate transporter.
3 n in the PCFT gene encoding a proton-coupled folate transporter.
4 of the recently reported human mitochondrial folate transporter.
5 cells occurs exclusively through the reduced-folate transporter.
6  human folate receptor and the human reduced-folate transporter.
7 te receptors are one of three major types of folate transporters.
8 ed to validate the functions of the putative folate transporters.
9 n cells that express only the proton-coupled folate transporter and accumulated folates by this mecha
10 orter is most closely related to the reduced-folate transporter and thus represents the second member
11       Reduced folate carrier, proton-coupled folate transporter, and folate-receptor alpha expression
12                                              Folate transporters are present throughout the terminal
13 ane of S180 cells by the one-carbon, reduced folate transporter as well as the KD for binding to the
14                              PSS30 encodes a folate transporter, AtFOLT1, which was previously locali
15  neural retina and uses not only the reduced-folate transporter but also the folate receptor alpha in
16 dentified a tandem array of genes encoding a folate transporter family, TbFT1-3, as major contributor
17 and thus represents the second member of the folate transporter family.
18 -of-function mutations in the proton-coupled folate transporter gene (pcft/SLC46A1) resulting in impa
19                                The effect of folate transporter gene ablation on colon carcinogenesis
20 n organization of the isolated mitochondrial folate transporter gene were deduced from the expressed
21 nization of the murine RFC-1 gene encoding a folate transporter has been determined.
22                                              Folate transporters have been characterized in the small
23 ecrease in mRNA levels of the proton-coupled folate transporter/heme carrier protein 1 (PCFT/HCP1) an
24 vating mutations in the human proton-coupled folate transporter (hPCFT) gene, which encodes the proto
25 n of the cDNA responsible for the intestinal folate transporter; iii) delineation of intracellular me
26 ork in a coordinated manner with the reduced-folate transporter in the vectorial transport of folate
27 ssion of the folate receptor and the reduced-folate transporter in these cells was evaluated by funct
28 ence of transcripts specific for the reduced-folate transporter in these cells.
29 PCFT was identified in 2006 as the principal folate transporter involved in the intestinal absorption
30                                       RFC, a folate transporter, is a potential receptor for the nove
31                  The mammalian mitochondrial folate transporter (MFT) is one of a few MCF members, kn
32                            The mitochondrial folate transporter (MFT) was previously identified in hu
33                        The CHO mitochondrial folate transporter (mft) was sequenced and compared with
34                           The proton-coupled folate transporter (PCFT) (also known as SLC46A1) mediat
35 or beta (IC50s < 1 nM) or the proton-coupled folate transporter (PCFT) (IC50 < 7 nM).
36 ith the recent cloning of the proton-coupled folate transporter (PCFT) and the demonstration that thi
37  folate carrier (RFC) and the proton-coupled folate transporter (PCFT) are ubiquitously expressed in
38 ivation of Cbs, Mthfr, or the proton-coupled folate transporter (Pcft) gene resulted in a 10- to 30-f
39               Recently, a new proton-coupled folate transporter (PCFT) in human intestine was reporte
40                           The proton-coupled folate transporter (PCFT) is a folate-proton symporter h
41                           The proton-coupled folate transporter (PCFT) is a folate-proton symporter w
42                           The proton-coupled folate transporter (PCFT) is a proton-folate symporter w
43                     The human proton coupled folate transporter (PCFT) is involved in low pH-dependen
44                           The proton-coupled folate transporter (PCFT) mediates intestinal folate abs
45 olate receptors (FRs) and the proton-coupled folate transporter (PCFT) over the reduced folate carrie
46                           The proton-coupled folate transporter (PCFT) plays a key role in intestinal
47 ely] into solid tumors by the proton-coupled folate transporter (PCFT) represents a novel therapeutic
48 PCFT) gene, which encodes the proton-coupled folate transporter (PCFT) SLC46A1.
49 olate receptor (FR) alpha and proton-coupled folate transporter (PCFT) uptake specificity over the re
50 it was only recently that the proton-coupled folate transporter (PCFT) was identified and its critica
51 reduced folate carrier (RFC), proton-coupled folate transporter (PCFT), and folate receptor alpha (FR
52 reduced folate carrier (RFC), proton-coupled folate transporter (PCFT), and folate receptors (FR) are
53 ate receptor alpha (FRalpha), proton-coupled folate transporter (PCFT), and reduced folate carrier (R
54 ), methionine synthase (MTR), proton-coupled folate transporter (PCFT), and reduced folate carrier (R
55  this laboratory identified a proton-coupled folate transporter (PCFT), with optimal activity at low
56                             A proton-coupled folate transporter (PCFT)-deficient mouse has been previ
57 olate receptors (FRs) and the proton-coupled folate transporter (PCFT).
58 duced folate carrier (RFC) or proton-coupled folate transporter (PCFT).
59 uced folate carrier (RFC) and proton-coupled folate transporter (PCFT).
60 ), folate receptors (FRs) and proton-coupled folate transporter (PCFT).
61 essed in EOCs, along with the proton-coupled folate transporter (PCFT); FRbeta is expressed on activa
62                           The proton-coupled folate transporter (PCFT, SLC46A1) is required for intes
63 -of-function mutations in the proton-coupled folate transporter (PCFT, SLC46A1) result in the autosom
64 plex 1 and 2 and requires the proton-coupled folate transporter (PCFT, SLC46A1).
65                           The proton-coupled folate transporter (PCFT; SLC46A1) is a proton-folate sy
66                           The proton-coupled folate transporter (PCFT; SLC46A1) mediates folate trans
67                     The human proton-coupled folate transporter (PCFT; SLC46A1) or hPCFT was identifi
68 l role of His residues in the proton-coupled folate transporter (PCFT; SLC46A1), which mediates intes
69  objective was to characterize expression of folate transporters/receptor (FT/R) and folate hydrolase
70 folate carrier (RFC), the major facilitative folate transporter, RFC expression may alter drug effica
71        The polarized distribution of reduced-folate transporter (RFT)-1 to the apical retinal pigment
72 ntial polarized distribution of the reduced- folate transporter (RFT-1) and folate receptor alpha (FR
73                   FRalpha is a high affinity folate transporter that is overexpressed by other tumors
74 vidence in these cells for expression of the folate transporter that prefers nonreduced folate as a s
75 ion of a human proton-coupled, high-affinity folate transporter that recapitulates properties of fola
76 s time FRalpha has only been considered as a folate transporter, these studies describe a novel role
77                                  The reduced-folate transporter was reported recently to be present i
78 undance of the heme importer, proton-coupled folate transporter, was related to neonatal SF (beta = 0
79 structure of the human RFC-1 gene encoding a folate transporter were determined.
80 termined by the type and levels of the major folate transporters, with PCFT and RFC prevailing over F