1 G15 protein and its conjugated proteins upon
forced expression.
2 Among them, Sox9 has unique capacity: its
forced expression accelerates differentiation of mouse E
3 Through
forced expression and knockdown of Cten in HCT116 and SW
4 Moreover,
forced expression and knockdown of SPZ1 in hepatoma cell
5 suppression of proliferation and invasion by
forced expression,
and significant stimulation of invasi
6 atial restriction and the ability to sustain
forced expression are important advantages over the curr
7 well as in inducing ectopic eye formation in
forced expression assays.
8 Knockdown and
forced expression experiments identified the receptor un
9 We probed, in
forced expression experiments, the capacity of PHOX2A to
10 CiaR, as a result of either ciaH deletion or
forced expression from a constitutive promoter, is a med
11 FOXP3 is exclusively expressed in Tregs and
forced expression in CD4(+)CD25(-) T cells can convert t
12 2(R65Q/W) in patient-derived lymphocytes and
forced expression in control CTLs and NK cells diminishe
13 ants disrupted periderm differentiation upon
forced expression in zebrafish embryos, suggesting that
14 pigenetically silenced in TOSE cells and its
forced expression increased TOSE colony size.
15 ture conditions, lentivirus-mediated miR-503-
forced expression inhibited EC proliferation, migration,
16 he nucleus of intestinal stem cells, and its
forced expression leads to enhanced Wnt signalling in cr
17 ASP2-interaction partner LL5beta by RNAi and
forced expression of a CLASP2 fragment blocking the CLAS
18 We recently observed that
forced expression of a combination of three transcriptio
19 acrophages with chemical AMPK activators, or
forced expression of a constitutively active form of AMP
20 ation of cleft palate and ectopic cartilage,
forced expression of a constitutively active form of BMP
21 Conversely,
forced expression of a constitutively active form of Yap
22 Forced expression of a constitutively active isoform of
23 This is rescued by
forced expression of a deacetylated CTTN mimetic.
24 ession in CP-CML, we examined the effects of
forced expression of a dominant-negative isoform of IKAR
25 vage of Septin-2 occurred at residue 306 and
forced expression of a non-cleavable Septin-2 restored c
26 rentiation and loss of self-renewal, whereas
forced expression of a polycistron construct encoding mi
27 We also show that
forced expression of a second oncogene in human cancer c
28 00% yield and purity in less than 2 weeks by
forced expression of a single transcription factor.
29 Interestingly,
forced expression of a stabilized derivative of beta-cat
30 Forced expression of a transgenic BCR or a BclxL transge
31 Moreover,
forced expression of A1 in CD8 T cells from OX40-deficie
32 canonical Wnt signaling introduced either by
forced expression of activated beta-catenin, or the smal
33 ssion of the transcription factor lhx1a, and
forced expression of activated forms of the lhx1a gene p
34 Moreover,
forced expression of activated NOTCH3 increased MSI-1 le
35 Furthermore,
forced expression of Adrx decreased TNFalpha-induced act
36 Forced expression of Agr2 is sufficient to promote the g
37 AIPL-1 is expressed in embryonic muscle, and
forced expression of AIPL-1 in adult muscle compensated
38 Forced expression of all four strands show cooperativity
39 Forced expression of Amigo2 in QRsP-11 cells increased l
40 role of CREBH in lipogenesis and lipolysis,
forced expression of an activated form of CREBH protein
41 Reciprocally,
forced expression of ARID1B inhibits Wnt/beta-catenin si
42 the survival and growth of T-ALL cells, and
forced expression of ARID5B in immature thymocytes resul
43 Forced expression of ARTN also dramatically enhanced tum
44 Forced expression of ASB2 degrades MLL and reduces MLL t
45 not expressed in mammalian MG after injury,
forced expression of Ascl1 in mouse MG induces a neuroge
46 We now test whether
forced expression of Ascl1 in mouse Muller glia in vivo
47 We previously reported that
forced expression of Ascl1 in vitro reprograms Muller gl
48 Here, we reveal that
forced expression of ATF3 in motor neurons of transgenic
49 Forced expression of ATF4 and CHOP protein before UVB ir
50 Although
forced expression of Bak markedly sensitizes toward p14(
51 Conversely,
forced expression of Bam in the lymph gland results in e
52 n experimental autoimmune encephalomyelitis,
forced expression of BCL6 in myelin oligodendrocyte glyc
53 ly downregulated in polarized Th9 cells, and
forced expression of BCL6 in Th9 cells impairs Th9 cell
54 after degenerative loss, could be driven by
forced expression of beta-catenin to act as hair cell pr
55 These effects are attenuated by
forced expression of Bmi-1, suggesting that PcG proteins
56 In contrast,
forced expression of Bnc1 modifies plasma membrane/cytos
57 Forced expression of bta-miR-23a mimics reduced lipid ac
58 Forced expression of c-myc in RGCs, either before or aft
59 Forced expression of c-MYC or loss of PP2A B56alpha, the
60 Consistently,
forced expression of C/EBP-delta increased VEGF-C and VE
61 fibroblasts toward a myocardial cell fate by
forced expression of cardiac transcription factors or mi
62 be reprogrammed to cardiac-like myocytes by
forced expression of cardiac transcription factors with
63 amming of fibroblasts into cardiomyocytes by
forced expression of cardiomyogenic factors, GMT (GATA4,
64 els of the T-cell receptor-CD3zeta chain and
forced expression of CD3zeta into SLE T cells restores I
65 Likewise,
forced expression of CD69 (but not expression of a CD69
66 Conversely,
forced expression of CD80 by ocular infection of mice wi
67 We found that
forced expression of Cdk6 promotes continued cell divisi
68 However,
forced expression of CDX1 in HCT116 leads to reduced clo
69 Differentiation can be facilitated by
forced expression of certain transcription factors (TFs)
70 Previous studies have shown that
forced expression of core cardiogenic transcription fact
71 However, inhibition of ILK after
forced expression of Cten abrogated the motility-inducin
72 Forced expression of Cxcl12, Fzd2, or Ifi27l2a increases
73 Forced expression of Cyclin B partially restored the G1
74 Conversely,
forced expression of Dally causes ectopic accumulation o
75 nduced pluripotent stem cells (iPSCs) by the
forced expression of defined transcription factors in so
76 Forced expression of defined transcriptional factors has
77 In particular,
forced expression of diacylglycerol kinase beta abrogate
78 Later endothelial ligand removal, or
forced expression of Dll4 or the glycosyltransferase Mfn
79 Forced expression of dma-1 in neurons with simple dendri
80 is blunted by the knockdown of Rac or by the
forced expression of dominant-negative Rac.
81 dipsin/C3a decreases the phosphatase Dusp26;
forced expression of Dusp26 in beta cells decreases expr
82 ld not be recovered by T-cell activation, by
forced expression of E2A or by the up-regulation of this
83 are two direct target genes of miR-495, and
forced expression of either of them can reverse the effe
84 Forced expression of embryonic dystrophin in zebrafish u
85 Importantly,
forced expression of Eomes partly protected TCF-1-defici
86 expression, migration and invasion, whereas
forced expression of EpCAM resulted in decreased ERK pat
87 Forced expression of EphA4 reversed the effects of miR-5
88 Forced expression of ERbeta1 promoted growth suppression
89 Forced expression of ERG in prostate tumor cell lines re
90 Conversely,
forced expression of Esg in intestinal progenitor cells
91 thelial regulator of splicing 1 (ESRP1), and
forced expression of ESRP1 in invasive mesenchymal breas
92 We further demonstrate that
forced expression of ESRP2 in immature mouse and human h
93 Here we show that
forced expression of FGFR3b-S249C, the most prevalent FG
94 Moreover,
forced expression of forkhead box protein O1 (FoxO1), an
95 ilia found elsewhere in the neural tube, and
forced expression of Foxj1 in neuroepithelial cells is s
96 Forced expression of FOXO1 also inhibited Runx2-promoted
97 Conversely,
forced expression of FOXO1 restricts vascular expansion
98 ion by Ikaros-mutant CD4(+) T cells, whereas
forced expression of Foxp3 was sufficient to inhibit thi
99 Forced expression of fragments expressing the antisense
100 Forced expression of full-length SHIP significantly redu
101 nge; these responses could be rescued by the
forced expression of full-length SSeCKS but not by an SS
102 Conversely,
forced expression of Gadd45a in muscle or cultured myotu
103 We found that, despite
forced expression of GARP on all T cells, stimulation th
104 We found that
forced expression of GAS5 blocked, but knockdown of GAS5
105 ely, administration of BMP signals to PSM or
forced expression of GATA family members in chick PSM ex
106 reduced glucose uptake that was reversed by
forced expression of Glut1.
107 Forced expression of GPR56 results in myotube hypertroph
108 f prostate cancer xenografts in SCID mice by
forced expression of GPx3 suggests a tumor suppression r
109 a direct phosphorylation by MAP kinases, and
forced expression of GRD does not suppress the effect of
110 Forced expression of HDAC3 also promotes the death of ra
111 Forced expression of HDAC3 induces death of otherwise he
112 Conversely,
forced expression of Helios in CD4(+)Foxp3(-) T cells re
113 Conversely,
forced expression of HMGA1 blocks differentiation of hES
114 Forced expression of Hmga2 resulted in increased chimeri
115 In addition,
forced expression of HPIP in K562 cells, a multipotent e
116 Forced expression of HRT2 demonstrated simultaneous repr
117 Forced expression of hsa-miR-125b in these cells resulte
118 Forced expression of hsa-miR-17* mimic and hsa-miR-30c i
119 4KO) in a lupus-like disease model driven by
forced expression of HSP gp96 at the cell surface (trans
120 Importantly,
forced expression of Hspa1a or inhibition of NF-kappaB s
121 We then use lentivirus-mediated
forced expression of human ETS2 to convert normal human
122 actions was restricted to myogenic cells, as
forced expression of ICAM-1 by fibroblasts did not augme
123 down-regulated in CIA mouse ankles receiving
forced expression of IL-27.
124 Forced expression of inhibitory Smads, including Smad6 a
125 Our analysis revealed that
forced expression of Irf4 repressed ES-DC development, w
126 Strikingly,
forced expression of isoform 5, which encodes only a 20-
127 nective tissue growth factor (CTGF), whereas
forced expression of Jun~FosB stimulated TNC and CTGF pr
128 Forced expression of KDM2B promotes immortalization by s
129 uripotent stem cell (iPSC) state through the
forced expression of key transcription factors, and in t
130 r transdifferentiation) usually requires the
forced expression of key transcription factors.
131 Forced expression of Kir2.1 in hESC-CMs led to robust ex
132 On the other hand,
forced expression of KLF14 leads to mitotic catastrophe.
133 Furthermore,
forced expression of KLF4 in the highly metastatic MDA-M
134 Knockdown of Klf5 or
forced expression of Klf4 inhibited stiff matrix-induced
135 Forced expression of LEF-1 enhanced T(FH) differentiatio
136 Further,
forced expression of lin-42a leads to anachronistic larv
137 Forced expression of Lin28B in embryonic mouse sympathoa
138 ly reprogrammed into a distinct cell type by
forced expression of lineage-determining factors.
139 Forced expression of LNK inhibits signaling by interfero
140 Furthermore,
forced expression of LNK reduced cell size, inhibited ce
141 ein (Map1b) gene enhancer and are rescued by
forced expression of Map1b as well as by both Nrf2 overe
142 uid and may be altered experimentally by the
forced expression of master regulators mediating cell li
143 Direct reprogramming can be achieved by
forced expression of master transcription factors.
144 Forced expression of MAT2A in RSG-treated HSCs lowered P
145 Forced expression of MCM8 in RWPE1 cells, the immortaliz
146 constitutively expressed in cancer cells and
forced expression of mda-7/IL-24 (Ad.mda-7) or SARI (Ad.
147 Forced expression of MeCP2-e2, but not MeCP2-e1, promote
148 s (iCPCs) from mouse adult fibroblasts using
forced expression of Mesp1, Tbx5, Gata4, Nkx2.5 and Baf6
149 mellitus, with this effect being reversed by
forced expression of microRNA-155.
150 'missing-self' response can be prevented by
forced expression of minimally polymorphic HLA-E molecul
151 inhibited EMT during tumorigenesis, whereas
forced expression of miR-1 or miR-200 inhibited both EMT
152 Forced expression of miR-125a resulted in elevated cellu
153 Cgi58, activators of lipolytic activity, and
forced expression of miR-145 attenuates lipolysis.
154 and represses Prdm16 and Ppargc1a, and that
forced expression of miR-150 attenuates the elevated exp
155 Forced expression of miR-150 dramatically inhibited leuk
156 cy in mice results in mild vascular defects,
forced expression of miR-155 causes endothelial hyperpla
157 Forced expression of miR-16 inhibited in vitro prolifera
158 Forced expression of miR-194 in breast cancer cells that
159 Luciferase assays demonstrated that
forced expression of miR-196b inhibited the FOS promoter
160 Forced expression of miR-196b significantly delays MLL-f
161 However,
forced expression of miR-21 rescued osteoclast developme
162 ively regulated after T cell activation, and
forced expression of miR-214 in T cells led to increased
163 Finally,
forced expression of miR-214-3p enhances the sensitivity
164 Forced expression of miR-214-3p in esophageal cancer cel
165 Forced expression of miR-22 significantly suppresses leu
166 Forced expression of miR-23b cluster or miR-125a-5p enha
167 Indeed,
forced expression of miR-29c strongly induced podocyte a
168 Forced expression of miR-486-5p enhanced the self-renewa
169 Forced expression of miR-486-5p inhibited NSCLC cell mig
170 marrow transplantation studies, we show that
forced expression of miR-495 significantly inhibits MLL-
171 Furthermore,
forced expression of miR-9 can significantly promote MLL
172 NA sponge can significantly inhibit, whereas
forced expression of miR-9 can significantly promote, ML
173 Forced expression of miR-98 in T cells resulted in suppr
174 sed with Onconase treatment, as well as with
forced expression of miRNA mimic and inhibitors.
175 Vector-based
forced expression of miRNA-768-3p complementary sequence
176 Furthermore,
forced expression of miRs diminished GCLC and GSR expres
177 Forced expression of MIST1 in PCs caused them to expand
178 In contrast,
forced expression of MITF in melanoma and colon cancer c
179 In murine models,
forced expression of MN1 in hematopoietic progenitors in
180 sease phenotype, we evaluated the effects of
forced expression of MNRR1 on the mitochondrial disease
181 Here, we show that
forced expression of MRTF-A in dermal fibroblasts stimul
182 Forced expression of MRTF-A precisely emulates the anti-
183 Forced expression of Msgn1 in NM stem cells in vivo redu
184 hese genes, Myc, is neuroprotective, whereas
forced expression of Myc induces Rattus norvegicus neuro
185 muscle cells directly into myogenic cells by
forced expression of MyoD represents one route to obtain
186 tiation of primary human skin fibroblasts by
forced expression of myogenic transcription factor MyoD,
187 Remarkably,
forced expression of myomaker in fibroblasts promotes fu
188 Forced expression of NANOG in epiblast stem cells is suf
189 Forced expression of necdin enhances mitochondrial funct
190 Together, our data suggest that
forced expression of Neurod1 programs intestinal epithel
191 Forced expression of Neurod1 throughout intestinal epith
192 equired for normal lethargus quiescence, and
forced expression of nlp-22 during active stages causes
193 Forced expression of NO66 promoted cell survival and inv
194 Forced expression of nonfunctional SVs conferred a survi
195 Forced expression of NRARP reduced the abundance of NICD
196 Accordingly,
forced expression of Numbl abrogated osteoclastogenesis
197 Forced expression of NUMBL inhibits osteoclast different
198 'Nurr1' here), inducing transcription, while
forced expression of Nurr1 reversed the loss of quiescen
199 NDRs can be restored by
forced expression of OCT4 in somatic cells but only when
200 erivation without the use of transgenes, and
forced expression of OCT4, KLF4, and KLF2 allows mainten
201 The stable
forced expression of Oct4A in normal human urothelial ce
202 We found that
forced expression of OPN in early vertical-growth-phase
203 rotein rapsyn in an isoform-specific manner;
forced expression of P1f in plectin-deficient cells resc
204 ed as cells differentiate into STB, and that
forced expression of p63 maintains cyclin B1 and inhibit
205 mogenesis; such effects could be reversed by
forced expression of PBX3.
206 Similarly, silencing of miR-21 or STAT3 and
forced expression of PDCD4 in arsenic transformed cells
207 Finally, cold, beta-agonists, or
forced expression of PGC-1alpha are unable to cause ther
208 Paradoxically,
forced expression of PGC-1alpha in muscle promotes diet-
209 Forced expression of PHF8 resensitizes ATRA-resistant AP
210 Forced expression of PIP2-binding-deficient mutants of v
211 Forced expression of plakoglobin in SLUG-high cells had
212 Forced expression of plasmids expressing mutant Ezrin (T
213 ltanonA strains lack sialidase activity, but
forced expression of pneumococcal NanA in GBS induced de
214 However,
forced expression of pneumococcal NanA in GBS removed te
215 Forced expression of POPDC1(S201F) in a murine cardiac m
216 Forced expression of putative interneuron markers Dmbx a
217 Forced expression of RARbeta reversed the effects of miR
218 Forced expression of recombinant afadin in pulmonary end
219 Forced expression of RORgammat successfully rescued TCF-
220 The epigenetically
forced expression of Runx2/p57 and osteocalcin, a classi
221 ocopies deficiency of calsyntenin 3beta, and
forced expression of S100b in brown adipocytes rescues t
222 Forced expression of S1P1 prevented the establishment of
223 Forced expression of SAP in SLE T cells normalized IL-2
224 Forced expression of SARI using an adenovirus (Ad.SARI)
225 Forced expression of Semaphorin-7a in ERF-overexpressing
226 Forced expression of SHANK2 in neuroblastoma cells resul
227 eversed the effects of miR-219 depletion and
forced expression of Shh phenocopied miR-219 deficiency.
228 We found that
forced expression of SIRT1 in non-transformed PZ-HPV-7 p
229 Forced expression of Six1 in the postnatal retina was su
230 ivity of normal mammary stem cells, and that
forced expression of Slug in collaboration with Sox9 in
231 Forced expression of SMAD7 in beta cells by itself was s
232 Forced expression of SOCS1 in macrophages depleted of ME
233 Remarkably,
forced expression of Sox factors, in combination with ot
234 omyelinated; this defect could be rescued by
forced expression of SOX10 and MYRF by mHTT hGPCs.
235 In contrast,
forced expression of Sox17 down-regulates ES cell-associ
236 We also show that stable
forced expression of SPDEF results in increased expressi
237 s or a hepatocyte cell line upregulates, but
forced expression of SRA inhibits ATGL expression and fr
238 Forced expression of Stat3 significantly increased Th17
239 Forced expression of STIM1 in cultured adult feline vent
240 d with IFN-gamma and lipopolysaccharide, and
forced expression of T-bet in these cells rescued IgG2a
241 Consistently, it was inhibited by
forced expression of T-bet or RORC2, the lineage-definin
242 Forced expression of TCF-1 in bone marrow progenitors pa
243 non-adipogenic fibroblasts, and, remarkably,
forced expression of TCF7L1 is sufficient to commit non-
244 Forced expression of Tfap2 in i-cells converted them to
245 LIF/Stat3- and 2i-mediated self-renewal, and
forced expression of Tfcp2l1 can recapitulate the self-r
246 Forced expression of TG1 or TG2 proteins is sufficient t
247 on and expression of ECM that are rescued by
forced expression of TGFbeta2.
248 In addition,
forced expression of the acinar-restricted transcription
249 Forced expression of the Bbeta subunit in primary human
250 Forced expression of the Bmi-1 polycomb protein in SCC-1
251 activation of the endogenous CA IX either by
forced expression of the dominant-negative DeltaCA varia
252 This phenotype could be rescued by the
forced expression of the GTPase-activating protein (GAP)
253 We found that IFN-gamma treatment or
forced expression of the IFN-induced GTPase, mGBP-2, inh
254 Forced expression of the irisin precursor Fndc5 in trans
255 We found that
forced expression of the Notch inhibitor NUMB in HepaRG
256 Forced expression of the relevant Numb splice isoform wa
257 Furthermore,
forced expression of the repressor isoform of Ovol2 is a
258 or example, in Drosophila female germ cells,
forced expression of the testis-specific PHD finger prot
259 Forced expression of the three transcription factors Sox
260 t stem cells (iPSCs) can be achieved through
forced expression of the transcription factors Oct4, Klf
261 Forced expression of the WT1(-KTS) isoform, which functi
262 We show that
forced expression of these exon regulatory elements coul
263 Forced expression of these factors in dividing non-cardi
264 Forced expression of these miRNAs suppressed MITF protei
265 The opposite occurred with
forced expression of these miRNAs.
266 Forced expression of these non-reprogrammed genes improv
267 Forced expression of these novel genes resulted in IL3-i
268 Intracerebroventricular infusion or
forced expression of this protein exacerbates neuroinfla
269 We recently reported that
forced expression of TIMP-2, as well as the modified for
270 ssue factor gene promoter was activated, and
forced expression of tissue factor cDNA was achieved in
271 Because
forced expression of TR2/TR4 in murine adult erythroid c
272 t fibroblasts can be converted to neurons by
forced expression of transcription factors.
273 Further, the
forced expression of TRPM2 mutant channel (C1008-->A) or
274 In addition,
forced expression of tuberin in tuberin-null cells aboli
275 Forced expression of TWIST1 on the left side induced ect
276 We found that
forced expression of V3 by ASMCs affected expression of
277 Forced expression of VEGF-C, but not recombinant VEGF-C,
278 ry development and in kidney cyst formation;
forced expression of vhnf1 mRNA led to rescue of the pk1
279 Forced expression of Vsig4 in mice ameliorates MHV-3-ind
280 RNAs identified Insulin-like Receptor (InR),
forced expression of which completely rescues lin-28-ass
281 Compared with
forced expression of wild type TDG, CRL4(Cdt2)- resistan
282 Conversely,
forced expression of wild-type CtBP2 in the knockdown ce
283 Forced expression of wild-type human VEGFC in the floorp
284 meliorated clinical symptoms in one patient;
forced expression of wild-type IL-2Rbeta also increased
285 Although
forced expression of wild-type p53 was not sufficient to
286 Using a combination of protein silencing and
forced expression of wild-type/constitutively active var
287 In fact, we show that
forced expression of Wip1 in premature senescent tumor c
288 e1 and Prickle2 in individual cells or local
forced expression of Wnt5a perturbed polarization of nei
289 Forced expression of WT or variant Kcnj2 changes the nor
290 on has been found in many human cancers, and
forced expression of XIAP blocks apoptosis.
291 Forced expression of Yap prolongs proliferation in the p
292 eobox 1 (ZEB1) in claudin-low tumor cells or
forced expression of ZEB1 in basal-like tumor cells, two
293 Forced expression of ZFP36L1 in cancer cells markedly re
294 Surprisingly,
forced expression of Zfp423 in myoblasts induces differe
295 Forced expression of Zfp488 gene in human NSCs led to th
296 Interestingly, the
forced expression of Zscan4 is required onlyfor the firs
297 Forced-expression of MICU1 in normal cells phenocopies t
298 MHC-I-dependent immune responses or to MHC-I
forced expression per se.
299 Conversely,
forced expression phenocopied Gsk3 inhibition or Tcf3 de
300 SCLC cells treated with combination of TUSC2
forced expression with erlotinib increased tumor cell ap