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1 those regions and eight are almost entirely foreign.
3 n was highest in non-Hispanic Asians in both foreign- (3.85%; 95% CI, 2.97-4.97) and U.S.-born (0.79%
5 herlands, Irish Aid, Australia Department of Foreign Affairs and Trade, and the Federal Ministry for
6 ation and Research, Australian Department of Foreign Affairs and Trade, Wellcome Trust, Department of
7 International Development, Dutch Ministry of Foreign Affairs, Bill & Melinda Gates Foundation, German
8 id from the UK Government, Dutch Ministry of Foreign Affairs, UNDP/UNFPA/UNICEF/WHO/World Bank Specia
9 finity for self-antigen 19-fold and increase foreign affinity 67-fold, to yield a more than 1,250-fol
10 s the VH186.2 H chain and recognize a common foreign Ag (the hapten 4-hydroxy-3-nitrophenylacetyl) bu
12 es (HLA-DR-SPs), peptides from MS-associated foreign agents (Epstein-Barr virus and Akkermansia mucin
13 requires TLR-MyD88 signaling independent of foreign agonists, and is further enhanced by CD40-CD40L
14 of populations of naive B cells specific for foreign Ags and a moderate level of cross-reactivity pri
15 B cell populations specific for a variety of foreign Ags express high levels of the orphan nuclear re
19 ries) that have not been heavily targeted by foreign aid and require health-care delivery infrastruct
20 or taxes than for nontax revenue from oil or foreign aid, giving rise to an important mechanism under
21 rich regions, consistent with the purging of foreign alleles more tightly linked to incompatibility l
22 the extent to which selection on deleterious foreign alleles will affect neutral alleles at physicall
23 TCR erroneously recognizes self-peptides as foreign and activates an immune response against healthy
25 at assessment, a pathogen recognized as both foreign and harmful will recruit an enhanced immune resp
27 pMHCII) repertoire by imposing a bias on the foreign and self-derived peptide cargos that are present
28 eceptor is limited by chemical similarity of foreign and self-peptides and very low concentrations of
29 sponse must resolve cross-reactivity between foreign and self-proteins bearing near-identical contact
31 whereas unmodified cap0-RNA is recognized as foreign and, therefore, potentially harmful to the host
35 ence, it would be desirable to identify such foreign-antigen triggers to provide a mechanistic unders
36 ) cells in controlling antibody responses to foreign antigens and autoantigens in vivo is still uncle
37 e responses by recognizing a large number of foreign antigens and thus, their genetic diversity plays
43 e B cell recruitment into immune response to foreign antigens vs. induction of tolerance to self-anti
44 ure to common antigens, previous exposure to foreign antigens was not the only force that shaped the
46 lymphocytes must respond to vast numbers of foreign antigens, including those of microbial pathogens
51 d to be catalytic, and indeed highlights how foreign assistance funding can be transformative, in red
52 residents along partisan lines, prohibits US foreign assistance to any organisation that performs or
53 lm X-rays, however, are only useful when the foreign bodies contain radiopaque material (metal, glass
56 ients with penetrating wounds with suspected foreign bodies retained in the wound are often seen in e
57 g pathogens, cell-cell fusion in response to foreign bodies, and their self-sacrifice as occurs durin
58 including damaged proteins, organelles, and foreign bodies, in a bulk, non-selective or a cargo-spec
66 fuse into multinuclear cells, also known as foreign body giant cells, to respond to the biomaterial
68 findings suggest that the eggshell inhibits foreign body granuloma formation long enough for the mir
69 positive blood cultures, >72 h of fever, or foreign body materials present), a normal echocardiograp
70 rifampin with vancomycin against MRSA in rat foreign body osteomyelitis, suggesting that rifabutin an
75 biomaterials implanted in the body induce a foreign body reaction characterized by chronic inflammat
79 s were wound healing problems (n = 270/56%), foreign body reactions (n = 58/12%), wound infections (n
81 ove (OR = 4.244, P-value< 0.001), history of foreign body removal (OR = 1.677, P-value = 0.041), and
85 cts generated from rECM bioinks suppress the foreign body response, are pro-angiogenic and support re
86 phasis on hydrogels designed to mitigate the foreign body response, provide a suitable extracellular
89 n about molecular factors that determine CNS foreign body responses (FBRs) in vivo, or about how such
93 ed regional fatty infiltration, 98% included foreign body, 45% had mural thickening and 20% localized
94 features were studied including radioopaque foreign body, mural thickness, fatty infiltration or ext
97 sions, CPR before defibrillation, removal of foreign-body airway obstruction, resuscitation care for
98 nce that among children of immigrants, being foreign born was associated with a long-term death penal
100 2% of US/Canadian-born compared with 2.3% of foreign-born contacts (P = .002), and TB rates for US/Ca
101 .002), and TB rates for US/Canadian-born and foreign-born contacts who did not initiate treatment wer
102 mmunity, whereas an increased risk among the foreign-born disappeared after multivariable adjustment.
103 tween age at immigration and death among the foreign-born individuals; however, those arriving during
106 blacks but not in other race/ethnicities and foreign-born persons and birth cohort born after 1985.
112 s associated with screening prevalence among foreign-born women included English fluency, recent US r
114 accination and screening between US-born and foreign-born women of reproductive age and examines pred
116 re are needed, especially for the uninsured, foreign-born, birth cohort after 1985 and certain ethnic
119 has evolved to distinguish between self and foreign, but they also enable development of novel thera
121 d FHL-1 for protection of different host and foreign cells (rabbit and yeast), we uncovered a 2-fold
125 lian cells possess innate immunity to detect foreign circRNAs, but the molecular basis of self versus
130 when China was the only large epicenter and foreign countries had not discovered extensive local tra
131 gal addition of water buffalo (WB) milk from foreign countries to the Italian counterpart devoted to
132 rategy to induce adaptive immunity against a foreign, crosslinked protein, chicken egg ovalbumin (OVA
133 NG) is a receptor in human cells that senses foreign cyclic dinucleotides that are released during ba
137 es on a combination of end joining to insert foreign DNA and HDR to repair collateral damage caused b
139 The arrays containing spacers derived from foreign DNA are transcribed, and the transcripts are pro
143 es RNases and DNases that may either destroy foreign DNA directly or elicit collateral damage inducin
145 Type I CRISPR-Cas systems typically target foreign DNA for degradation via joint action of the ribo
148 ne of the main mechanisms of defence against foreign DNA invasion and can have an important role in t
149 ing infection by harmful SGEs, the uptake of foreign DNA is evolutionarily maintained by the hosts, e
152 could lead to increased integration rates of foreign DNA within the recipient cell during DNA repair.
153 se in H-NS abundance reduces H-NS binding to foreign DNA, allowing transcription of foreign genes, in
154 uplication or mutation but also by acquiring foreign DNA, also called horizontal gene transfer (HGT).
155 , the Cas1-Cas2 complex selects fragments of foreign DNA, called prespacers, and integrates them into
166 journal, and the AJO had boasted a number of foreign editorial board members and collaborators over t
168 ue 2D structure enables the intercalation of foreign elements or molecules, which makes BP directly r
169 e is a common response to different types of foreign elements that includes a response to proteotoxic
173 cate that antibodies have been elicited to a foreign epitope that includes a heptosyl residue unique
176 nsferases promote heritable silencing of the foreign gene gfp, but are dispensable for silencing of t
181 ructuring) protein silences transcription of foreign genes in a variety of Gram-negative bacterial sp
183 y manipulate the viral genome to express two foreign genes offers the possibility of developing novel
186 To take advantage of the products encoded in foreign genes, bacteria must overcome the silencing effe
187 lts from functional replacement of native by foreign genes, functional mitochondrial gene transfer to
188 ng to foreign DNA, allowing transcription of foreign genes, including those required for intramacroph
189 oted H-NS proteolysis, thereby de-repressing foreign genes-even those whose regulatory sequences are
193 germline genome is guarded against invading foreign genetic elements by small RNA-dependent gene-sil
196 s2 complex that integrates short segments of foreign genetic material (spacers) into the CRISPR locus
197 types, likely owing to their sensitivity to foreign genetic material or virus-based manipulation.
199 sicular stomatitis viruses (rVSV) expressing foreign glycoproteins (GP) have shown promise as experim
201 functional protein even after transfer to a foreign host is of fundamental importance in both evolut
203 pletes cytoplasmic RNA that is recognized as foreign in mammalian cells by virtue of its elevated CG
204 lues progress and success partially owing to foreign influence and immigrants, similarly the internat
205 field of crystallization are the impurities, foreign ingredients that are either deliberately added t
206 acteria possess an array of defenses against foreign invaders, including a broadly distributed bacter
211 s, but when the body recognizes the graft as foreign, it is rejected by this process, often with fata
214 proposes that T cells discriminate self from foreign ligands by the different ligand binding half-liv
216 = 144) relax in response to eight unfamiliar foreign lullabies, relative to matched non-lullaby songs
217 ere we show that goods produced in China for foreign markets lead to an increase of domestic non-meth
218 ned as the complete engulfment of a piece of foreign material, depends on the mechanical properties o
219 ature predominantly freezes with the help of foreign materials through a process known as heterogeneo
221 issues, surrounded by unfamiliar cells and a foreign microenvironment, are likely to die; however, th
225 m by which the innate immune system measures foreign nucleic acid length, a common criterion for self
226 e an RNA-guided multiprotein complex to find foreign nucleic acids and trigger their destruction.
227 Proteins called RNA and DNA sensors detect foreign nucleic acids and, in mammalian cells, include R
228 eceptors sample subcellular compartments for foreign nucleic acids and, upon recognition, trigger imm
230 rference and suggest that the recognition of foreign nucleic acids by prokaryotic defence systems inv
231 chanisms, some of which target the incoming, foreign nucleic acids e.g. restriction-modification (R-M
233 ble sensing of multiple distinct features in foreign nucleic acids, including structure, length, and
234 ded protein surveillance complexes recognize foreign nucleic acids, triggering their destruction by C
240 ystem has the challenging task of tolerating foreign nutrients and the commensal microbiome, while ex
241 s in preclinical studies, the electrodes are foreign objects and might therefore be expected to induc
242 particles, and in order to capture and trap foreign objects, one of their strategies is to release n
243 e (AMP) synthase (cGAS) recognizes cytosolic foreign or damaged DNA to activate the innate immune res
246 mportant protective response that eliminates foreign organisms, damaged cells and physical irritants;
249 rovide fast-acting immune protection against foreign pathogens, while also sustaining tolerance to se
250 d epitope sources and by presenting the same foreign peptides and autoantigens to autoreactive CD4(+)
251 cells are thought to discriminate self from foreign peptides by converting small differences in liga
254 ings suggest that US visa policies may deter foreign PhDs from working in startups, thereby restricti
256 en startups and established firms and not by foreign PhDs' preferences for established firm jobs, ris
259 very of surgical care by both Guatemalan and foreign physicians was affected by practice in the STM s
260 in facilitating the T cells' hunt for a rare foreign pMHC ligand and the induction of rapid T cell re
263 sociality: Return rates for both Italian and foreign recipients are the same; they vary together; and
264 r results show that the carbon footprints of foreign regions in China are concentrated in key manufac
267 -Cas systems provide robust immunity against foreign RNA and DNA by sequence-specific RNase and targe
269 isplays rapid conformational fluctuations on foreign RNA targets, but is locked in a static configura
270 e cyclic oligoadenylate (cOA) upon detecting foreign RNA, activating ancillary nucleases that can be
272 ever, the limited capacity for incorporating foreign sequences in the viral genome forced researchers
274 tive to matched non-lullaby songs from other foreign societies, as indexed by heart rate, pupillometr
275 tion (translation and popularization) of the foreign sources that informed the theories they built up
286 ration of DTCs that had recently infiltrated foreign tissue by binding to syndecan receptors expresse
287 initiate rapid proliferation after entering foreign tissue, which likely contributes significantly t
291 everse transcriptase to acquire spacers from foreign transcripts, most contain conventional spacer ac
295 ered mechanism enables a pathogen to express foreign virulence genes during infection without the nee
297 articipants were re-exposed to prior learned foreign vocabulary during up- and down-states of slow os