ライフサイエンスコーパス: form

1 of the predicted targets with the canonical form.

2 an from a CbpD-sensitive to a CbpD-resistant form.

3 election are influenced by peripheral visual forms.

4 istinct neutrophil granules are successively formed.

5 isomers of a dimeric oxidation product were formed.

6 gow Outcome Scale-Extended (GOSE), the Short Form-12v2 and a battery of cognitive tests.

7 e largest centre reported satisfactory Short Form-36 evaluated health-related quality of life at 1-ye

8 Orb2 formed ~75-nanometer-long threefold-symmetric amyloid fi

9 , T(4)PE(4)NDI can be selectively excited to form a charge-separated state via ultrafast photoinduced

10 les with TMEM43, ENDOD1, TMEM33 and TMED1 to form a complex capable of modulating innate immune signa

11 Mechanistically, TALP-3 and ANKR-26 form a complex with key gating component DYF-19, the hom

12 regulatory subunits of these AHAS complexes form a core to which the catalytic subunit dimers are at

13 trate alpha-amino group on the sn-2 ester to form a cyclic tetrahedral intermediate that then collaps

14 The glucocorticoid receptor (GR) and KLF15 form a feed-forward transcription loop that cooperativel

15 We demonstrate that DarT(Mtb) -DarG(Mtb) form a functional TA pair and essentiality of darG(Mtb)

16 pH-sensitive peptide that self-assembles to form a hydrogel at neutral pH.

17 intimately connected FAPI crystallites which form a mesoporous architecture.

18 fl) mouse TIA1 spontaneously oligomerizes to form a metastable colloid-like suspension.

19 involves an initial allylic substitution to form a new Michael acceptor, followed by the addition of

20 y stages of cytokinesis, FtsZ protofilaments form a ring-like structure, the Z-ring, in most bacteria

21 g and nondrug reward are linked and together form a risk profile for drug use or abuse, particularly

22 ated electrolytes, surface coatings that can form a solid electrolyte interphase with a high interfac

23 les flood rhodopsin upon light absorption to form a solvent-swollen active state.

24 g intramuscular immunisation, GBS67-CpGODN+L formed a vaccine depot at the injection site and induced

25 to the presence of a gasket-like structure (forming a canopy above the collar filters).

26 r in a magnitude close to the energy cost of forming a knot randomly in the denatured state.

27 cting the molecule with atomic precision and forming a molecular bridge between the metallic STM tip

28 nsidered to be a putative marker for Y cells forming a motion processing stream, we suggest that pecu

29 posterior lateral and posterior (PO) nuclei, forming a pair of recurrent cortico-thalamo-cortical (C-

30 UCC1 forms a central CS nanodomain in comparison with other C

31 The DEC-205 monomer forms a compact structure comprising two intercalated ri

32 Here, we show that human METTL2 forms a complex with DALR anticodon binding domain conta

33 In eukaryotes, Spt5 forms a complex with Spt4 and regulates processive trans

34 yeast two-hybrid analysis suggest that ZC3H5 forms a complex with three other proteins, encoded by ge

35 Indeed, TMG-SYNPHOS forms a copper complex that catalyzes hydroboration of 1

36 HsZnT8 forms a dimeric structure with four Zn(2+) binding sites

37 integration with the Ensembl project, which forms a key part of our future strategy for dealing with

38 This RGC network forms a new electrical channel combining the ON and OFF

39 We show that CSB forms a stable complex with Pol II and acts as an ATP-de

40 teraction is distinct from HPRT in that XPRT forms a symmetric dimer with two (p)ppGpp binding sites

41 Epithelial cells spontaneously form acini (also known as cysts or spheroids) with a sin

42 with a spectrum of heterolytic covalent-bond-forming activity (that is, reacting diversely with small

43 The surface Al(2)O(3) layer, formed after an initial thermal oxidation, supports a wi

44 n ring hydroxylation, we identified products formed after the initial reaction between HO(*) or SO(4)

45 ally interconvert between cyclic and acyclic forms, alone or in the presence of glycine under moderat

46 N-terminal region, scaffolds the L-type pore-forming alpha1 subunit and, through its C-terminal regio

47 We find that in addition to forming amyloid, PAP(248-286) much more readily assemble

48 e thumb, palm, and fingers subdomains of POL form an extensive interface with the primer-template and

49 When a T cell and an antigen-presenting cell form an immunological synapse, rapid dynein-driven trans

50 both languages and automata recognizing them form an inclusive hierarchy.

51 n of CLK1 is dependent on a Michael acceptor forming an irreversible bond with Cys 215 in the ATP-bin

52 Our results indicate that HA forms an adsorbed surface layer, but its charge, thickne

53 its the glycosylation of NCSTN to its mature form and impairs the integrity of the gamma-secretase co

54 hondrial matrix, but how mtDNA nucleoids are formed and regulated within cells remains incompletely r

55 ) to potentially predict the titanium oxides formed and their stability with reference to the mole fr

56 ic resistance genes characterized by biofilm-forming and human-microbiome-influenced environments wit

57 trates the importance of an intact alcove in forming and stabilizing the Ni(I)-CO intermediate in the

58 oreceptor-bound or coreceptor-unbound (free) forms, and we here present evidence that the two pools o

59 c, fewer than 10% of the US adult population formed antibodies against SARS-CoV-2, and fewer than 10%

60 licase, Mcm2-7, in inactive double hexameric form around DNA.

61 gled with CrO(4)(2-), calcite and gypsum are formed as secondary mineral phases, which allows for oxy

62 occurring mainly in proteolytically cleaved form, as membrane-spanning C-terminal fragments of the p

63 ylglycerol (TAG)-synthases Lro1 and Dga1 are formed at discrete ER subdomains defined by seipin (Fld1

64 Multi-enhancer interactions formed at genomic regions harboring genes with prominent

65 The 2D-GMs are formed at low onset potential and can be in situ doped d

66 tudy provides firm evidence that methanol is formed at the interface of Pt NPs and linker-deficient Z

67 g pathways (in which intermolecular contacts form before or concurrently with the secondary structure

68 actin-binding interface and active site have formed before producing a power stroke.

69 Using MS, we identified an ester bond formed between a thermolysin serine residue and the A2ML

70 target cell receptors, an immunocomplex was formed between anti-CD20 antibodies and lymphoma cancer

71 tly enable PHD2 crystallization in different forms, both with/without substrates, apparently by promo

72 gamma-aminobutyric acid (GABA) at non-image-forming brain targets.

73 tendency to undergo rearrangement, sometimes forming bridged ions, as well as their ability in many c

74 rete fibronectin and its binding proteins to form bridges of extracellular matrix that ligate the sev

75 NA approaches, gammaPNA structures appear to form bundles of nanofibers.

76 tinal pigment shield of T. evanescens is not formed by a separate cell type, but by extensions of the

77 odefined boron-stabilized allylic Cu species formed by an enantioselective transmetalation.

78 ydrophobic trimethyl-L-lysine-binding 'cage' formed by BAHCC1(BAH), mediating colocalization of BAHCC

79 cs over relatively low-dimensional manifolds formed by correlated patterns of neurons.

80 pontaneously produced in water microdroplets formed by dropwise condensation of water vapor on low-te

81 aster via the isomer (C(6)H(4), O)(C, N, Ph) formed by P-stereomutation involving a M(B2) permutation

82 These radical intermediates are formed by the direct oxidation of a B-B bond between a b

83 Resistance mapping revealed a druggable site formed by the G protein fusion loops that has not previo

84 iation, with the alternative diastereoisomer formed by use of a deuterium blocking group.

85 ibit the tumor-initiating cell's neurosphere-forming capacity, and migration.

86 imeric compounds were found to be capable of forming co-gels with the catalytically active hexameric

87 y virtue of its similarity to bacterial pore-forming colicins.

88 f multiple homologous chromosomes, which can form complex multivalent configurations at metaphase I,

89 This intermediate is formed concurrently to the oxidation of CoOOH to CoO(2).

90 t glycolytic protein PFK-1.1 can dynamically form condensates in vivo.

91 ganizes around tip-gated microcantilevers to form contracting CaMiRi.

92 PDA is also able to form coordination bonds with various metal ions, which c

93 e show helminths synthesize two coq-2 splice forms, coq-2a and coq-2e, and the coq-2e-specific exon i

94 strongly improves the molecular anchoring by forming covalent bonds between molecular carbon and copp

95 t HIV-1 types (B and circulating recombinant forms [CRFs] CRF01_AE, CRF07_BC, CRF08_BC, and CRF55_01B

96 on of coadsorbed acetaldehyde and ethanol to form crotyl alcohol and water.

97 (DFT) calculations, redox disproportionation forms [Cu(III)](C=CAr)(R) species that reductively elimi

98 s approach makes use of a reactive linker to form cyclic peptides on the phage surface while simultan

99 pathways dysregulated in kidneys destined to form cysts.

100 dergo liquid-liquid phase separation (LLPS), forming dense droplets that are increasingly understood

101 his empirical study identifies the key urban form determinants of decadal-long fine particulate matte

102 val.SIGNIFICANCE STATEMENT Visual arrestin-1 forms dimers and tetramers.

103 The Wtf4(poison) protein forms dispersed, toxic aggregates.

104 Components of these pathways localize to, or form distinct aggregates in the vicinity of, germ granul

105 giant branch stars <4.9 Ga ago that possibly formed during an episode of enhanced star formation ~7 G

106 loops (D-loops) are signature intermediates formed during homologous recombination.

107 d regional distribution of HIV-1 recombinant forms during 1990-2015.

108 We then apply reduced-form econometric methods, commonly used to measure the e

109 f the endogenous virus against the exogenous form, either via direct interference or indirectly via g

110 Class I adenylate-forming enzymes share a conserved structural fold but ac

111 ral information in the human brain needed to form episodic memories.

112 -forms hydrolysis, being both free and bound forms equally affected by temperature.

113 ld then prevent reversion to the unassembled form, even if assembly per se does not enhance biologica

114 +4) , confirming the importance of the newly formed excited-state manifold in TBPCExBox(4+) for the p

115 evidence for the ability of photosystems to form extended manganese oxide particles.

116 st crisis phase cell lines, Kcl-22 and K562, formed few or no TNTs.

117 It forms fibrils both under cellular stress and in mutated

118 nella serotypes Typhimurium and Newport also formed floccular biofilms.

119 While l-morph individuals form flowers with long styles, short anthers, and small

120 orm the input into a structurally accessible form for circuit wiring, translate the input information

121 ed molecules and measures of exact masses of formed fragment ions, it could be concluded that some of

122 Discrete VFs initially formed from each virus that subsequently coalesced from

123 Instead, carbonate radical anion is formed from the Fenton reaction under cellular condition

124 Large bottlebrush complexes formed from the polysaccharide hyaluronan (HA) and the p

125 Here, the response of tumour spheroids formed from two established human cancer cell lines (HCT

126 The more superficial part of the canal forms from an open primary canal that closes and then re

127 Phylogenetic analyses reveal that these form-function associations reflect convergence towards p

128 f ipsilateral projections of CSNs, which can form functional connections with spinal neurons.

129 struct is polyhedric, comprising several key forms: grandiose versus vulnerable, agentic versus commu

130 acroscopic interconnected aggregate clusters form, grow, fuse, and evolve via internal rearrangement,

131 In contrast, p190A forms harboring recurrent cancer mutations exhibit loss

132 e tetrapyrrole protoporphyrin IX in order to form heme that is required for growth stimulation and su

133 Although conventional homoepitaxy forms high-quality epitaxial layers(1-5), the limited se

134 dergo liquid-liquid phase separation (LLPS), forming highly dynamic liquid droplets.

135 ure range tested had a minor effect on bound-forms hydrolysis, being both free and bound forms equall

136 anscriptional RNA/DNA hybrids (R-loops) that form in infected cells during S-phase as a consequence o

137 ls both under cellular stress and in mutated form in neurodegenerative conditions.

138 The narrow gateways that porins form in the OM are also exploited by bacteriocins to tra

139 The largest quantities of products were formed in food models at pH 6.4, which is close to the p

140 that complex PCB 11 metabolite profiles are formed in HepG2 cells that warrant further toxicological

141 In vivo studies in which the hydrogels were formed in situ over stromal keratectomy wounds without s

142 stream and a stream of collection medium, is formed in the curved channel.

143 presumed to be devoid of water because they formed in the inner Solar System.

144 entire compositional range of material that formed in the protoplanetary disk.

145 upported both types of memories if they were formed in the same environment, even at temporally disti

146 The furan products are formed in up to 93% yield using 5-10 mol % ZrCl(4).

147 ny bacteria cycle between sessile and motile forms in which they must sense and respond to internal a

148 llows us to identify their specific isomeric form, including the anomericity of the glycosidic linkag

149 Bacterial dormancy can take many forms, including formation of Bacillus endospores, Strep

150 The amount of MeIQ formed increased with reaction time, temperature, and ox

151 their organellar cargo and the grooves they formed indenting MCs, which was consistent with holotomo

152 y degraded and mu1 is cleaved and exposed to form infectious subvirion particles (ISVPs).

153 However, 2D COFs typically form insoluble aggregates, thus limiting their processin

154 cular dynamics simulations on eight BAK1 mod-forms involving phosphorylation of the four activation-l

155 Puzzlingly, this form is predicted to impede electrical conduction to an

156 This form is preserved when changing clock reference frames,

157 ence of emulsifier, hindered the polymorphic form IV-to-V transition.

158 Kv2.1 in arterial smooth muscle cells is to form K(+) channels in the sarcolemma.

159 s uniquely situated in the periodic table to form kinetically stable compounds often with chemically

160 d resulted in an inability of these cells to form labeled plasmalogens from labeled alkylglycerols.

161 learning stimulus, juv ELE and juv-adol ELE formed lasting long-term memory for an object location m

162 ill combine into coherent percepts of visual forms, like pixels on a video screen.

163 es of Abeta oligomers, which reveal how they form lipid-stabilized pores that might disrupt neuronal

164 s that the baboon amylin, like human amylin, forms low-order oligomers in the lag phase of amyloid fo

165 e channel of the device became polarized and formed mature tight junctions, that the permeability of

166 rved after training did not require sleep to form memories.

167 n vitro formulation development for hydrogel-forming microneedle arrays containing esketamine.

168 l and divergent kinesin-14 family members to form neocentromeres.

169 ar nucleus that was repeatedly duplicated to form new regions.

170 Synaptogenesis is essential in forming new neurocircuits during development, and this i

171 Tumor and stromal cells cooperated in forming niches; stromal cells produced predominantly cor

172 iomolecule, this information is shown in the form of a genus trace plot, as well as a genus matrix di

173 res to generate a concise feature map in the form of a two-dimensional image by minimizing the pairwi

174 uses upregulation of a constitutively active form of acetylcholine-dependent K(+) current (I(KACh)),

175 tinal atrophy, previously suggested as a new form of advanced AMD, and herein replicated.

176 Glioblastoma is a devastating form of brain cancer.

177 antigen receptor (CAR) T cells offer a novel form of CAR-T-cell product that is available for immedia

178 Ferroptosis is a regulated form of cell death that occurs when phospholipids with p

179 soluble natural products, thereby defining a form of contact-dependent, aquatic chemosensation.

180 acquisition and use of cystine, the oxidized form of cysteine, as a source of cellular sulfur.

181 n their retention at the cell surface in the form of functional gap junctions indicating that Abeta(2

182 t stem cell (iPSC) disease model of a common form of heart disease involving the aortic valve (AV).

183 Selective logging is the dominant form of human disturbance in tropical forests, driving c

184 mated fish to test whether plasticity in the form of inducible warm tolerance also evolved.

185 l cues but also their prior knowledge of the form of language.

186 terium lepromatosis was identified in a rare form of leprosy known as diffuse lepromatous leprosy (DL

187 hort-term and seasonal energy storage in the form of liquid fuels.

188 c costs for individuals and economies in the form of lost wages and productivity, as well as higher m

189 genomic landscape of acral melanoma, a rare form of melanoma occurring on palms, soles or nail beds,

190 Anxiety disorders are the most common form of mental illness and are more likely to emerge dur

191 ained a highly specialized horse-facilitated form of mobile pastoralism.

192 s that TAT-RasGAP(317-326) kills cells via a form of necrosis that relies on the physical disruption

193 this pore leads to necroptosis, a regulated form of necrotic cell death.

194 Ferroptosis is an iron-dependent form of nonapoptotic cell death associated with oxidized

195 o siblings displaying an autosomal recessive form of NS with massive hypertrophic cardiomyopathy as c

196 The role of lipid peroxidation, a potent form of oxidative stress, in mediating RV hypertrophy an

197 Here we describe an ultrasensitive form of polymerization-based regulation employed by huma

198 Using an integration-activated form of RAG1 with methionine at residue 848 and cryo-ele

199 ciently incorporates the active triphosphate form of RDV (RDV-TP) into RNA.

200 Imaging revealed an atypical form of rhombencephalosynapsis, a distinctive brain malf

201 s is toxic or that it reflects a more severe form of schizophrenia.

202 el cell carcinoma (MCC), an extremely lethal form of skin cancer.

203 This form of social learning is argued to reflect novel forms

204 Here, we report that an active form of the ESCRT-associated protein ALIX efficiently re

205 generating (i.e. biological) process and the form of the statistical analysis produce major conceptua

206 est that M.EcoGII may represent an ancestral form of these enzymes, as its activity is independent of

207 acute malnutrition (SAM) is the most serious form of undernutrition, characterized by wasting with or

208 well as the potential function of a secreted form of vCD200.

209 re also revealed the arrangement of multiple forms of alpha- and beta-polypeptides in an individual L

210 There are two stoichiometric forms of alpha4beta2 nAChRs, (alpha4)(3)(beta2)(2) and (

211 Familial forms of Alzheimer's disease (FAD) are caused by mutatio

212 hundred five unrelated probands with various forms of cardiomyopathy were evaluated.

213 inducing unresolvable UPR and possibly other forms of chemotherapy helping in a better stratification

214 ) lead to prototypical yet poorly understood forms of childhood-onset and complex hereditary spastic

215 biobanks to reveal other monogenic atypical forms of diabetes is an important approach to gaining in

216 asic pathogenic differences exist in the two forms of diabetes mellitus; T1DM is immune mediated and

217 ar and tear on the body and may lead to many forms of disease.

218 ses to degrade structured RNA during several forms of environmental stress.

219 ing focal seizures (EIMFS) and several other forms of epilepsy associated with severe intellectual di

220 es have explored the importance of different forms of extracellular PDL1, such as on exosomes or as a

221 are capable of transcribing novel unspliced forms of HIV-RNA transcripts with competent open reading

222 l immunomodulatory effects as seen for other forms of immunotherapy(3).

223 or reasoning about more abstract, conceptual forms of knowledge.

224 variants in genes associated with monogenic forms of neurological and psychiatric disorders in indiv

225 rane fusion is regulated by the ratio of two forms of Opa1.

226 We first review various forms of recent 3D MEAs for in vitro studies in context

227 lly separable pairs of enantiomerically pure forms of regioisomeric methyl half esters.

228 gress will impact the academic sector as new forms of research based on large amounts of data will be

229 s-retinal are associated with mild to severe forms of retinal dystrophy.

230 ith the emergence of new and more horizontal forms of social differentiation across genders.

231 f social learning is argued to reflect novel forms of social hierarchy in human societies, and, by pr

232 to reflect the outcome of activity-dependent forms of synaptic plasticity, yet activity-independent p

233 ly present with high lethality in the severe forms of the disease.

234 gration (the target capture complex) and two forms of the RAG strand transfer complex that differ bas

235 Here, utilising activated truncated forms of the receptors, we show that ADGRE2/EMR2 and ADG

236 ctive, simply reflect milder and more severe forms of the same diathesis.

237 his study, we engineered and selected mutant forms of uPlm that are both catalytically active and ins

238 erkingdom communities within intact biofilms formed on teeth of toddlers with caries.

239 lanthanide(III)-coordinated crossing pattern formed only with a copper(I)-coordinated crossing of par

240 spontaneously in physiological conditions to form paired helical filament-like fibres in vitro in the

241 Several H-H bond forming pathways have been proposed for the hydrogen evo

242 We find that the most potent pore-forming peptides exhibit strong interpeptide interaction

243 ed helix-loop-helix (H-L-H) was suggested to form pores by virtue of its similarity to bacterial pore

244 e challenged with 2 subfibrillar, non-plaque-forming prion strains instead developed plaques highly e

245 hyde (ACMS), can nonenzymatically cyclize to form quinolinic acid, the precursor for de novo biosynth

246 The observed constant free to bound forms ratio showed that the temperature range tested had

247 Intermolecular C-C bond-forming reactions are underdeveloped transformations in

248 in carbon-carbon and carbon-heteroatom bond-forming reactions, these have numerous crucial limitatio

249 Ki-67 forms repulsive molecular brushes during the early stage

250 anagement and the outcome of the most severe forms requiring ICU admission.

251 an adult-onset Pkd2 mouse model before cysts formed revealed significant differentially expressed gen

252 se, part-by-part-toward the ultimate goal of forming RNA and DNA by polymerization.

253 fication and its position within the i-motif forming sequence.

254 mic data, we show that putative G-quadruplex forming sequences (pG4) in 5' and 3' UTRs are selectivel

255 rowths along different lateral directions to form six-pointed Au nanostars.

256 ov cyclization, a [4+2] cycloaddition of the formed six- or seven-membered ring-fused cyclopentadiene

257 t-based mechanism that enables Drosophila to form sleep-dependent and sleep-independent memory.

258 pable of rapid aggregation, albeit initially forming smaller, weakly self-associated, acutely synapto

259 n of basaltic rock dust, including via newly formed soil carbonate minerals whose long-term fate requ

260 (100-300 nm diameter) in pH 7.5 solution and formed some bundles in pH 6.5 solution.

261 LK1-overexpressing primary human hepatocytes formed spheroids in suspension cultures.

262 enotypic variant, termed as F-type, fails to form spores, does not confer plant growth-promoting effe

263 tate both the Mn-I exchange and the C-C bond-forming steps.

264 -length TDP-43 and its CTD are also known to form stress granules by coacervating with RNA in the cyt

265 ionic transport under high sulfur loading by forming sufficient triple-phase boundaries between catal

266 ehavior, equimolar mixtures of MG2a and PGLa formed surface-aligned fibril-like structures, which ind

267 le circuits, combined into complex circuits, form systems-level functions.

268 blish a pH-dependent oligomerization pathway forming tetrameric DEC-205 using solution-based techniqu

269 symmetric Ni/Cr-mediated coupling is used to form the C19/C20 bond effectively.

270 s a specialized layer of the visual DVR that form the core of a dense network of highly specific conn

271 ansition metal dichalcogenide semiconductors form the foundation of modern electronics and optoelectr

272 transfer reaction from rhodium to carbon to form the H-C bond.

273 sm of the initial bimolecular association to form the intermediate state can be mediated by many poss

274 ve changes in the dynamics of the loops that form the knot.

275 An estimation of the times required to form the loops of typical sizes seen in Hi-C experiments

276 The proteins MCU and EMRE form the minimal functional unit of the mitochondrial ca

277 , and then combining its output responses to form the overall ensemble output.

278 functional, 18 structural), and 40 patients formed the reference group.

279 GIC, as demonstrated by an essential role in forming the replication vacuole of Legionella pneumophil

280 ledged but poorly quantified phenomenon that forms the basis for the development of TBV.

281 pair, and epigenetic modification, chromatin forms the nexus of most nuclear processes.

282 The set of possible niches forms the niche space, a conceptual space delineating wa

283 Ca(2+)-facilitated hydrogen-bonding network forms the structural basis of the unusual LH1 redshift.

284 After 4 h, the myosins form thick bipolar and, for smooth muscle myosin, side-p

285 hat are linked via a shared wing membrane to form this metamaterial, and collectively they generate h

286 irialized structures in the Universe and are formed through the gravitational accretion of matter ove

287 Previous efforts to form two-dimensional dilute magnetic semiconductors util

288 Analogue experiments on phyllosilicates formed under low temperature aqueous conditons have illu

289 Otherwise, all gas bubbles that form undergo, possibly oscillatory, growth and then diss

290 meter-monodisperse populations of nanofibers formed using analogous DNA approaches, gammaPNA structur

291 hydrides and activated esters were tested to form various bisphosphinates.

292 In contrast, the silica scale layer was formed via polymerization of silicic acid and gelation o

293 ular consumption of which occurs via the cis form when the terminal oxygen atom of the NOO moiety rea

294 Initially, corrosion etch pits are formed, which reflect the local symmetry of the surface:

295 t Trypanosoma brucei rhodesiense bloodstream forms, which is another important aetiological kinetopla

296 t, aqueous films of nonuniform thickness are formed while the filter paper is pressed against the sub

297 distress syndrome (ARDS) in the most severe form, while children are largely spared from respiratory

298 olume-temperature domain even if its typical form with constant scaling exponent is not obeyed.

299 These can be larger than those formed with lateral inhibition.

300 , indicating meter sized crystals could have formed within days, if these rates are sustained through