ライフサイエンスコーパス: formate dehydrogenase

1 uring the amount of released formate using a formate dehydrogenase.

2 (420)-nonreducing hydrogenase or formate via formate dehydrogenase.

3 ogenase, F(420)-nonreducing hydrogenase, and formate dehydrogenase.

4 s, such as carbon monoxide dehydrogenase and formate dehydrogenase.

5 tory ribulose monophosphate cycles, and by a formate dehydrogenase.

6 expression of carbon monoxide dehydrogenase, formate dehydrogenase A and hydrogenases in the Deltaagr

7 a subset of the Mo trait, presumably due to formate dehydrogenase, a Mo- and selenium-containing pro

8 ulation of phosphate-dependent repression of formate dehydrogenase-a key enzyme in the methanogenesis

9 e activity, including nickel homeostasis and formate dehydrogenase activities as well as molybdopteri

10 hicus and S. wolfei had both hydrogenase and formate dehydrogenase activities.

11 ophy has been slow energy supply due to slow formate dehydrogenase activity.

12 he soluble Fe(III) reductase did not possess formate dehydrogenase activity.

13 The first gene cluster encodes homologs of formate dehydrogenase alpha (FdhA) and beta (FdhB) subun

14 sharing relatively low similarity with known formate dehydrogenase alpha subunits.

15 ogenase FdsABG is a soluble NAD(+)-dependent formate dehydrogenase and a member of the NADH dehydroge

16 upled to H(+)/CO(2) reduction by periplasmic formate dehydrogenase and hydrogenase via a flavin-based

17 haracterization of a complex metal dependent formate dehydrogenase and provide an understanding of th

18 cinate requires their oxidation by the Fdh-N formate dehydrogenase and succinate dehydrogenase respec

19 li strains as model organisms indicated that formate dehydrogenase and terminal oxidase genes provide

20 ampylobacter jejuni, possesses a periplasmic formate dehydrogenase and two terminal oxidases, which s

21 ron transfer could proceed via a periplasmic formate dehydrogenase and/or hydrogenase, allowing energ

22 that all molybdenum- and tungsten-containing formate dehydrogenases and related enzymes likely operat

23 when introduced alongside non-native energy (formate dehydrogenase) and carbon-fixing (RuBisCO, phosp

24 doxins from Acetobacterium and hydrogenases, formate dehydrogenase, and cytochromes of Desulfovibrio

25 int assay based on the coupled reaction with formate dehydrogenase, and measuring consumption of O(2)

26 ific activities of GSH-FDH, an NAD-dependent formate dehydrogenase, and the key Calvin-Benson-Bassham

27 sigma(E) and cytoplasmic membrane-associated formate dehydrogenase are required for the protective ef

28 effects on the oxidation of formate by yeast formate dehydrogenase as expressed on the kinetic parame

29 ecting multiple periplasmic hydrogenases and formate dehydrogenases, as a key feature of its energy m

30 immobilized CO(2) reduction enzymes-such as formate dehydrogenase-can operate with high turnover and

31 BiVO(4):Mo (light absorbers), hydrogenase or formate dehydrogenase (cocatalyst), and a molecular coba

32 Here, we implement a fast, metal-dependent formate dehydrogenase complex in a synthetic formatotrop

33 an decrease the cellular pH, the addition of formate dehydrogenase could also maintain the cellular p

34 , the ability of Desulfovibrio desulfuricans formate dehydrogenase (Dd FDH) to reduce carbon dioxide

35 Analyzing a formate dehydrogenase domain that is evolutionarily rela

36 The formate dehydrogenase-encoding fdhCAB operon and flankin

37 rode allowed the targeted orientation of the formate dehydrogenase enzyme from Rhodobacter capsulatus

38 Escherichia coli possesses three distinct formate dehydrogenase enzymes encoded by the fdnGHI, fdh

39 By comparison, the formate dehydrogenase enzymes operate at relatively mild

40 TP-derived molybdenum cofactor in homologous formate dehydrogenase enzymes.

41 ron transfer flavoproteins, hydrogenases and formate dehydrogenases essential for syntrophic metaboli

42 RHE)), CO(2) is reduced to HCOO(-) using a W-formate dehydrogenase (FDH(NvH)) from Nitratidesulfovibr

43 Surprisingly, formate dehydrogenase (FDH) activity was decreased appro

44 a kinetic model of the cell-free kinetics of formate dehydrogenase (FDH) and 2,3-butanediol dehydroge

45 fatty acids, dissimilatory sulfur oxidation, formate dehydrogenase (FDH) and a nitrite reductase (Nir

46 torquens AM1 with lesions in genes for three formate dehydrogenase (FDH) enzymes was previously descr

47 biocatalyst support material, and the enzyme formate dehydrogenase (FDH) for selective CO(2)-to-forma

48 Furthermore, co-expressing formate dehydrogenase (Fdh) from Candida boidinii increa

49 Here, a CO(2) reductase, formate dehydrogenase (FDH) from Desulfovibrio vulgaris

50 Here, we couple formate dehydrogenase (FDH) from Desulfovibrio vulgaris

51 0 insertion library revealed that mutants in formate dehydrogenase (FDH) genes had the highest surviv

52 al transcriptomics revealed that 2 of the 23 formate dehydrogenase (FDH) genes known in the system ac

53 biosynthesis genes, and upregulation of fdh4 formate dehydrogenase (FDH) genes.

54 Formate dehydrogenase (FDH) has been studied in bacteria

55 Formate dehydrogenase (Fdh) is essential for formate oxi

56 reaction come from either formate or H2 via formate dehydrogenase (Fdh) or Hdr-associated hydrogenas

57 TON(syngas) = 48), whereas immobilization of formate dehydrogenase (FDH) produces formate (TON(format

58 We report a study of formate dehydrogenase (FDH) that compares the temperatur

59 formate hydrogenlyase (FHL) complex links a formate dehydrogenase (FDH) to a hydrogenase (H(2)ase) a

60 doreductase (WOR1) and a tungsten-containing formate dehydrogenase (FDH), along with an electron bifu

61 products, including CO2 This organism lacks formate dehydrogenase (Fdh), which catalyzes the reducti

62 coli, deletion of ubiquinone (UQ) synthesis, formate dehydrogenases (FDH), NDH-1, or cytochrome bd-I

63 cription and activity of the donor complexes formate dehydrogenase (FdhABC) and hydrogenase (HydABCD)

64 homologs of fdhF encoding hydrogenase-linked formate dehydrogenases (FDHH ) and all other components

65 Metal-dependent formate dehydrogenases (FDHs) are of considerable intere

66 Metal-dependent formate dehydrogenases (FDHs) catalyze the reversible co

67 revealed that C. albicans upregulates three formate dehydrogenases (FDHs) during coculture; we show

68 -pyranopterin guanine dinucleotide family of formate dehydrogenases (FDHs) plays roles in several met

69 dhD, a protein essential for the activity of formate dehydrogenases (FDHs), which are iron/molybdenum

70 xygenase (AmoABC), manganese oxidase (MnxG), formate dehydrogenase (FdoGH and FDH), and carbon monoxi

71 The oxygen-tolerant and molybdenum-dependent formate dehydrogenase FdsDABG from Cupriavidus necator i

72 ate is assimilated via oxidation to CO(2) by formate dehydrogenase, followed by CO(2) fixation by the

73 ining genetically encoded and co-immobilized formate dehydrogenase for NADH regeneration and leucine

74 erface with enzymes, namely hydrogenases and formate dehydrogenases, for semi-artificial photosynthes

75 D(+) to NADH by an NAD(+)-cofactor-dependent formate dehydrogenase from Candida boidinii (FDH(CB)).

76 salvage pathway as well as an NAD+-dependent formate dehydrogenase from Candida boidinii.

77 The ability of the FdsABG formate dehydrogenase from Cupriavidus necator (formerly

78 we have examined the ability of the FdsDABG formate dehydrogenase from Cupriavidus necator to cataly

79 d identity to the respective subunits of the formate dehydrogenase from Moorella thermoacetica, but t

80 In this study, W-containing formate dehydrogenase from Nitratidesulfovibrio vulgaris

81 lybdenum-containing, NAD(+)-dependent FdsABG formate dehydrogenase from Ralstonia eutropha.

82 the FdsBG subcomplex of the cytosolic FdsABG formate dehydrogenase from the hydrogen-oxidizing bacter

83 d this by including the gene (fdh), encoding formate dehydrogenase from Xanthobacter sp. 91 (XaFDH),

84 The molybdenum- and tungsten-containing formate dehydrogenases from a variety of microorganisms

85 Phylogenetic analysis suggested that the two formate dehydrogenase gene sets arose from duplication e

86 trophicus expressed multiple hydrogenase and formate dehydrogenase genes during syntrophic benzoate a

87 To study the latter, we identified the formate dehydrogenase genes of M. maripaludis and found

88 h organisms contain multiple hydrogenase and formate dehydrogenase genes, but lack genes for outer me

89 idase family of enzymes, the 5' deiodinases, formate dehydrogenases, glycine reductase, and a few hyd

90 The selenocysteine-containing formate dehydrogenase H (FDH) is an 80-kDa component of

91 of the oxidized [Mo(VI), Fe4S4(ox)] form of formate dehydrogenase H (with and without bound inhibito

92 differentially regulated genes revealed that formate dehydrogenase H and fumarate reductase are impor

93 mitant decrease in (75)Se incorporation into formate dehydrogenase H and nucleosides of bulk tRNA was

94 2-), failed to synthesize selenium-dependent formate dehydrogenase H and seleno-tRNAs.

95 Molybdenum-containing formate dehydrogenase H from Escherichia coli (EcFDH-H)

96 Formate dehydrogenase H from Escherichia coli contains s

97 ytic properties of the molybdenum-containing formate dehydrogenase H from the model organism Escheric

98 guanine dinucleotide [MGD]) synthesis, or in formate dehydrogenase H synthesis were all defective in

99 icodons enabled E. coli to synthesize active formate dehydrogenase H, a selenoenzyme.

100 Formate dehydrogenase H, FDH(Se), from Escherichia coli

101 ermed Hyd-3), FdhF (the molybdenum-dependent formate dehydrogenase-H), and three iron-sulfur proteins

102 Formate dehydrogenase has traditionally been assumed to

103 e, itself linked to an unusual selenium-free formate dehydrogenase in the final complex.

104 teps of methanogenesis, including one of two formate dehydrogenases, increased with H2 starvation but

105 (cyanide and carbon monoxide), but not by a formate dehydrogenase inhibitor (hypophosphite).

106 rinsic kinetic isotope effects of the enzyme formate dehydrogenase is used to examine the distributio

107 he mutants suggest that any one of the three formate dehydrogenases is sufficient to sustain growth o

108 A soluble formate dehydrogenase lends additional ecophysiological

109 r the production of xylitol, coexpression of formate dehydrogenase, mannitol dehydrogenase, and a glu

110 Expression of genes for the second formate dehydrogenase, molybdenum-dependent formylmethan

111 rease in formic acid secretion relative to a formate dehydrogenase mutant (fdh1 fdh2), while formic a

112 The structure of the membrane protein formate dehydrogenase-N (Fdn-N), a major component of Es

113 Formate dehydrogenase-N is a three-subunit membrane-boun

114 port infrared photon echo measurement of the formate dehydrogenase-NAD+-azide ternary complex.

115 s of the DMSOR family (e.g., DMSO reductase, formate dehydrogenase, nitrite oxidoreductase, and arsen

116 e selenocysteine into any of the three known formate dehydrogenases of E. coli.

117 brid photocatalyst consisting of immobilized formate dehydrogenase on titanium dioxide (TiO(2) |FDH)

118 framework (MOF), termed NU-1006, containing formate dehydrogenase, on a fluorine-doped tin oxide gla

119 Of the two formate dehydrogenases, only the first could support gro

120 o stimulate or suppress expression of either formate dehydrogenase operon via NarL and NarP.

121 s) among these species, including a complete formate dehydrogenase operon, genes required for N-acety

122 gene expression profiles of the alternative formate dehydrogenase operons suggest that the two enzym

123 necessary for gauging the ability of a given formate dehydrogenase or other CO2-utilizing enzyme to c

124 de reductase are strict molybdoenzymes while formate dehydrogenase prefers tungsten.

125 echanistic proposals for hydride transfer in formate dehydrogenase proceed through a classic metal hy

126 tory nitrate reductase (QR' = 2-AdS(-)), and formate dehydrogenase (QR' = 2-AdSe(-)).

127 hydrogenase reaction (GndA and GndB) and the formate dehydrogenase reaction (FDH1 and FDH4).

128 le for utilization, while a highly efficient formate dehydrogenase reduces CO(2) cleanly to formate;

129 te dehydrogenase, alcohol dehydrogenase, and formate dehydrogenase, respectively).

130 The formate dehydrogenase subunit FdoH and the yet uncharact

131 pproach was used to identify three different formate dehydrogenase systems in the facultative methylo

132 These results demonstrated that all three formate dehydrogenase systems must be inactivated in ord

133 iently interconverted by tungsten-containing formate dehydrogenases that surpass current synthetic ca

134 Coupled with NADPH-recycling via formate dehydrogenase, these interventions enable effici

135 tablish an optimal local environment for a W-formate dehydrogenase to perform electrocatalysis.

136 In analogy to the well-known formate dehydrogenase to promote NADH-dependent reaction

137 rate CO(2) reduction systems from enzymatic (formate dehydrogenase) to heterogeneous systems.

138 ectrons are channeled from an outward-facing formate dehydrogenase via menaquinones to a fumarate red

139 Hydrogenase-linked formate dehydrogenase was also affected, but not as seve

140 Formate dehydrogenase was present in most selenoproteome

141 ies, we conjugated mannitol dehydrogenase to formate dehydrogenase with the defined active site arran

142 cales of active-site motions in complexes of formate dehydrogenase with the transition-state-analog i

143 fully balanced site saturation libraries of formate dehydrogenase, with diversities of 2x10(4) .