ライフサイエンスコーパス: formyl

1 n/ion-mediated peptide derivatization with 4-formyl-1,3-benezenedisulfonic acid (FBDSA) anions using

2 es with a second population of chromogenic 4-formyl-1,3-benzenedisulfonic acid (FBDSA) anions to prom

3 ion/ion reactions with doubly deprotonated 4-formyl-1,3-benzenedisulfonic acid (FBDSA) in the gas-pha

4 le 4-bromo-2-triisopropylsilyloxyfuran and 2-formyl-1,3-dithiane.

5 2-methoxycarbonyl-, 2-aminocarbonyl-, and 2-formyl-1,4-benzodioxane, are key synthons that for the m

6 on of a trigonal prismatic cage, utilizing 2-formyl-1,8-naphthyridine subcomponents to bind pairs of

7 coordinative flexibility of silver and the 2-formyl-1,8-napthyridine subcomponent.

8 , 5-hydroxymethyl-2'-deoxycytidine (hmdC), 5-formyl-2'-deoxycytidine (fdC) and 5-carboxy-2'-deoxycyti

9 e normal one from the tumor's margin; also 5-formyl-2'-deoxycytidine and 5-carboxy-2'-deoxycytidine w

10 idine, 5-(hydroxymethyl)-2'-deoxycytidine, 5-formyl-2'-deoxycytidine, 5-carboxy-2'-deoxycytidine, 5-(

11 ificantly lower yields of products such as 5-formyl-2'-deoxyuridine that are ascribable to deprotonat

12 tic studies indicate that the oxidation of 5-formyl-2-furancarboxylic acid (FFCA) to FDCA is the slow

13 The 3-formyl-2-furylcarbinols are further elaborated in two st

14 fficiently provide, in one step, access to 3-formyl-2-furylcarbinols, which are otherwise only access

15 ones (2-pyridone, 3-chloro-2-pyridone, and 3-formyl-2-pyridone) have been examined in the gas phase u

16 nm range induced direct transformation of 2-formyl-2H-azirine into 3-formylketenimine; (ii) irradiat

17 found to isomerize into several products: 2-formyl-2H-azirine, 3-formylketenimine, 3-hydroxypropenen

18 Treatment of 3,5-diformyl BODIPYs or alpha-formyl 3-pyrrolyl BODIPY with different alkyl/aryl ylide

19 ure of ATI-5261 to acrolein resulted in N-(3-formyl-3,4-dehydropiperidino) (FDP)-lysine adducts at po

20 rimidinamine dihydrochloride), and KNK437 (N-Formyl-3,4-methylenedioxy-benzylidine-gamma-butyrolactam

21 A-EDA [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate], starting from natura

22 Triplet syn-2-formyl-3-fluorophenylnitrene, generated in argon matrice

23 ochalcogen compounds derived from 2-chloro-1-formyl-3-hydroxymethylenecyclohexene (16) are described.

24 roscopy and a sensing ensemble composed of 2-formyl-3-hydroxypyridine (4) and Fe(II)(TfO)(2).

25 cles having Pt(IV) ion were prepared from (4-Formyl-3-methoxyphenoxymethyl) polystyren, glycine and P

26 prepared using the nanoparticles modified (4-Formyl-3-methoxyphenoxymethyl) with polystyren (FMPS) wi

27 1-(3'-Formyl-4'-hydroxyphenyl)-8-(9'-anthryl)naphthalene (1) w

28 1-(3'-Formyl-4'-methoxyphenyl)-8-(4'-isoquinolyl)naphthalene N

29 and 12 led to the formation of (Z)-1,2-bis(2-formyl-4-((2E)-1-methylbut-2-en-1-yl)phenyl)diazene-1-ox

30 grees C followed by reaction with DMF gave 2-formyl-4-chloro-3-fluoropyridine 10 regioselectively, wh

31 aldehyde functionalized ionic liquid, (3-(3-formyl-4-hydroxybenzyl)-3-methylimidazolium hexafluoroph

32 1, 2-formyl-5-(2-methoxyphenyl)-pyrrole, which was weakly cor

33 )-l-tryptophan (ARP), Tryptophol (TRO), 2-(2-formyl-5-(hydroxymethyl-1H-pyrrole-1-yl)butanoic acid (P

34 4-Formyl-5-methoxyisoxazoles give methyl oxazole-4-carboxy

35 -hydroxymelatonin [6(OH)M], N(1)-acetyl-N(2)-formyl-5-methoxykynuramine (AFMK) and 5-methoxytryptamin

36 es: 6-hydroxymelatonin (6-OHM), N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), N-acetylserotonin (NA

37 xygenases generate 5-hydroxymethyl (5hmC), 5-formyl (5fC), and 5-carboxyl (5caC) derivatives; thus, D

38 oxidations to the 5-hydroxymethyl (5hmC), 5-formyl (5fC), and 5-carboxyl (5caC) forms.

39 r oxidation to the 5-hydroxymethyl (5hmC), 5-formyl (5fC), or 5-carboxyl (5caC) forms.

40 d to the concise synthesis of glycozoline, 3-formyl-6-methoxy-carbazole, and 6-methoxy-carbazole-3-me

41 iously-reported low-spin Fe(II)4L4 cage 2: 2-formyl-6-methylpyridine was ejected in favor of the less

42 ect of 1.8 on the imine reduction to preQ1 7-Formyl-7-deazaguanine, a carbonyl analogue of the imine

43 nd its function was evaluated in AMs using 8-formyl-7-hydroxy-4-methylcoumarin (4mu8C), an inhibitor

44 The reaction between substituted 1-formyl-9H-beta-carbolines and terminal alkynes in the pr

45 f functional groups (e.g., halogen, nitrile, formyl, acetyl, ester).

46 clocondensation of beta-ketosulfones 1 and o-formyl allylbenzenes 2 provides sulfonyl oxabenzo[3.3.1]

47 on, as well as methodologies to modify the N-formyl amide of the resultant cycloaddition product, are

48 ion between the two carbonyl groups of the N-formyl amide.

49 inetic resolutions of alpha-stereogenic-beta-formyl amides in asymmetric 2-aza-Cope rearrangements ar

50 thro-pentafuranosyl)-2,6-diamino-4-hydroxy-5-formyl amidopyrimidine (Fapy-dG), is associated with pro

51 The limit of detection (LOD) for N-formyl amphetamine was determined to be 10muM in this ca

52 -mdC) in DNA to yield the 5-hydroxymethyl, 5-formyl and 5-carboxyl derivatives of 2'-deoxycytidine (5

53 With DMF, abstraction occurs from the formyl and N-methyl C-H bonds, with the formyl being the

54 alpha-sulfonyl o-hydroxyacetophenones with 2-formyl azaarenes (pyridines and quinolones) provides aza

55 the formyl and N-methyl C-H bonds, with the formyl being the preferred abstraction site, as indicate

56 The method uses thermally stable 4-formyl benzamide functionalized (4FB) magnetic beads rat

57 acid (TFA) results in peptides that have a 4-formyl-benzamido group where the nitro group used to be.

58 Enantiopure 4-formyl-beta-lactams were deployed as synthons for the di

59 ions afford the substituted cis-1-hydroxyl-8-formyl-bicyclo[4,3,0]non-8(9)-enes or bicycle[4,3,0]non-

60 e identify a reactive pathway in amides, the formyl C-H abstraction, not currently considered in stru

61 ormamides HAT preferentially occurs from the formyl C-H bond, while in N-formylpyrrolidine HAT mostly

62 ations with hydrocarbon lengths ranging from formyl (C1) to palmitoyl (C16) as well as negatively cha

63 with additional functional handles, such as formyl, chloromethylketone, and iodide.

64 In a second step, formyl-CoA is decarbonylated, resulting in free CoA and

65 10)-formyl-THF to produce formyl-coenzyme A (formyl-CoA) as a central reaction intermediate.

66 The enzymes YfdW, a formyl coenzyme A (CoA) transferase, and YfdU, an oxalyl

67 formyl group of N(10)-formyl-THF to produce formyl-coenzyme A (formyl-CoA) as a central reaction int

68 The rhodium formyl complex ((tmtaa)Rh-C(O)H) was isolated under a CO

69 m equilibrium distributions with hydride and formyl complexes ((tmtaa)Rh-H (2); (tmtaa)Rh-C(O)H (3)).

70 reactions of (tmtaa)Rh-H with CO to produce formyl complexes in toluene (K2(298 K)(tol) = 10.8 (1.0)

71 Eleven formyl-containing BODIPY dyes were prepared by means of

72 hydroxymethyl dihydroxypyrrolidines from C-2 formyl D-glycals has been described via a common dicarbo

73 5-Formyl-dC (fdC) and 5-carboxy-dC (cadC) are newly discov

74 the stoichiometric reduction of CO to give a formyl derivative which reacts further via an epoxy-bora

75 benzo[e]indol-4-ol led selectively to the 5-formyl derivative, which is a good precursor for an unus

76 3-H4folate, followed by a plateau due to the formyl derivatives and minor compounds stability.

77 The conjugate addition of N-formyl derivatives of 2-amino-3-iodo- and 3-amino-4-iodo

78 on of the corresponding 5-hydroxymethyl or 5-formyl derivatives, respectively, in turn prepared via m

79 hermal treatment, with a better retention of formyl derivatives.

80 key equilibration of a formyl imine to an N-formyl enamine.

81 size a BODIPY dimer by McMurry coupling of a formyl Et2B-BODIPY, while a new BODIPY with an asymmetri

82 O/S-carbamates, benzoyl ureas, amides, and N-formyls, exploiting the Curtius reaction.

83 ate to 8-amino-FMN via the intermediacy of 8-formyl-FMN.

84 The azaBODIPYs containing one and two formyl functional groups on the 1,7-aryl groups present

85 of N-formyl-protected glycine as the ligand (Formyl-Gly-OH) was crucial for the development of this r

86 eliver 2,4-cyclohexadienones featuring a key formyl group and a quaternized carbon atom in good yield

87 etic version that features the transfer of a formyl group and hydride from an aldehyde substrate to a

88 de starting with intramolecular capture by a formyl group and termination by capture with HFIP solven

89 n the B ring of a tetrapyrrole molecule to a formyl group by chlorophyllide a oxygenase (CAO).

90 We found that the 5-formyl group could increase duplex thermal stability and

91 of the chlorophylls and the formation of the formyl group in Chl f.

92 Our results showed that the 5-formyl group is located in the same plane as the cytosin

93 However, the biochemical provenance of this formyl group is unknown.

94 because the hydroxymethyl group of 5hmC and formyl group of 5fC adopt restrained conformations throu

95 the methyl group of BChlide c or d into the formyl group of BChlide e or f This probably occurs by a

96 d (2)H) to determine the origin of the C2(1)-formyl group of Chl f and to verify whether Chl f is syn

97 the multidomain protein, HypX, converts the formyl group of N(10)-CHO-THF into water and CO, thereby

98 dence that purified HypX first transfers the formyl group of N(10)-formyl-THF to produce formyl-coenz

99 A structure-activity study showed that the formyl group on position 1 and the bromine atom on posit

100 We found that the oxygen atom of the C2(1)-formyl group originates from molecular oxygen and not fr

101 imidazoles, and pyrazoles substituted with a formyl group react with an aminocatalyst to generate an

102 hifted absorption maximum because of a C2(1)-formyl group substitution of Chl f However, the biochemi

103 Formyl group substitutions on the side chains of chlorop

104 construction of pyrroles bearing a 2-keto or formyl group through the intramolecular oxidative aza-an

105 the ortho'-substituent is a nonnucleophilic formyl group, the products include fused indanylnaphthal

106 s to novel polycyclic scaffolds decorated by formyl groups and carboxylates suitable for subsequent m

107 CH...O hydrogen bonds involving formyl groups have been invoked as a crucial factor cont

108 nvestigation to ortho'-substituted vinyl and formyl groups.

109 The formyl-H KIEs are (D)k = 0.80 in 200 mM HCl, (D)k = 0.77

110 Solvent (D2O) and secondary formyl-H kinetic isotope effects (KIEs) were measured by

111 drolase complex (Fhc) generates formate from formyl-H(4)MPT in two consecutive reactions where MYFR a

112 ) O) at 5 K via barrierless recombination of formyl (HCO) and hydroxycarbonyl radicals (HOCO) is repo

113 oxygen of the boronate and is oriented by a formyl hydrogen bond (Goodman model) and by other electr

114 H...O hydrogen bond and the secondary CH...O formyl hydrogen bond as the reaction occurs.

115 The strength of the formyl hydrogen bond in the TS, a second CH...O interact

116 the phosphoryl oxygen of the catalyst to the formyl hydrogen of the aldehyde.

117 ith CuCN catalyzing a key equilibration of a formyl imine to an N-formyl enamine.

118 end of an O-bound CO, which forms an eta(2)-formyl intermediate that adds, in a second step, the bor

119 oxylate, l-thiazolidine-2-carboxylate, and N-formyl l-proline (NFLP).

120 ethynyl)-pyridine], the DGL inhibitor THL [N-formyl-l-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetan

121 C reduction in the presence and absence of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) (1 mu

122 e released from HeLa cells stimulated with N-Formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) and a

123 es, (iii) chemotaxis towards chemoattractant formyl Met-Leu-Phe (fMLP) coupled with their decreased p

124 ecylmaltoside extracts of unstimulated and N-formyl-Met-Leu-Phe (fMLF) + cytochalasin B-stimulated ne

125 ted in impaired chemotactic migration toward formyl-Met-Leu-Phe (fMLP) and stromal cell-derived facto

126 horylated in response to the chemoattractant formyl-Met-Leu-Phe (fMLP) in adherent cells.

127 as studied here using the bacterial peptide, formyl-Met-Leu-Phe (fMLP), as an RB inducer.

128 f Escherichia coli and the chemoattractant N-formyl-Met-Leu-Phe (fMLP)-coated beads.

129 gen and decreased neutrophil chemotaxis to a formyl-Met-Leu-Phe gradient.

130 entraxin 3 and induced the apoptosis of both formyl-Met-Leu-Phe or LPS-activated neutrophils and LPS-

131 ainst a bacterially derived chemoattractant (formyl-met-leu-phe, fMLP), with and without preactivatio

132 e seen for the natural chemotactic peptide n-formyl-Met-Leu-Phe.

133 beyond the earlier described isoleucine and formyl methionine tRNAs, and suggest that various GNAT t

134 -mediated intermediary chemotaxis, whereas N-formyl-methionine-leucine-phenylalanine receptor-mediate

135 actin to filamentous actin in response to N-formyl-methionine-leucine-phenylalanine, resulting in si

136 and basophil HR in response to anti-IgE and formyl-methionine-leucine-phenylalanine.

137 lk of the 50S, and on its deletion, proper N-formyl-methionyl(fMet)-tRNA(fMet) positioning and effici

138 wever, P. stomatis significantly increased N-formyl-methionyl-leucyl phenylalanine (fMLF)-stimulated

139 activity of alphaMbeta2 integrin following N-formyl-methionyl-leucyl phenylalanine stimulation.

140 inophil responsiveness upon stimulation with formyl-methionyl-leucyl phenylalanine was found to ident

141 Furthermore, on FPR1 activation with N-formyl-methionyl-leucyl phenylalanine, WDR26 dissociates

142 eceptor (FPR) on neutrophils, which binds to formyl-methionyl-leucyl-phenylalanine (fMLP) and plays a

143 nases (MAPK)] were assessed in response to N-formyl-methionyl-leucyl-phenylalanine (fMLP) stimulation

144 Secondary stimulation of PMNs with 1 muM N-formyl-methionyl-leucyl-phenylalanine (fMLP) triggered e

145 When neutrophils were exposed to formyl-methionyl-leucyl-phenylalanine (fMLP), PKCbetaII

146 receptor in the CNS, and also reduces the N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced neu

147 lpha, was used to examine the mechanism of N-formyl-methionyl-leucyl-phenylalanine (fMLP)-mediated fo

148 of the microbiota-produced N-formyl peptide, formyl-methionyl-leucyl-phenylalanine, are elevated in h

149 13, in basophils stimulated with anti-IgE, N-formyl-methionyl-leucyl-phenylalanine, or phorbol 12-myr

150 suppressed basophil activation induced by N-formyl-methionyl-leucyl-phenylalanine, phorbol 12-myrist

151 ation in the presence of the chemoattractant formyl-methionyl-leucyl-phenylalanine.

152 n incubated with concentrations of anti-IgE, formyl-methionyl-leucylphenylalanine (fMLP), or the Ca(2

153 tion containing beta-lysyl-EF-P stimulated N-formyl-methionyl-puromycin synthesis approximately 4-fol

154 S initiation complexes (ICs) that carry an N-formyl-methionyl-tRNA (fMet-tRNA(fMet)).

155 s a number of one-carbon unit intermediates (formyl, methylene, methenyl, methyl).

156 reveals that the methyl, hydroxymethyl, and formyl modifications are easily accommodated within the

157 due to the presence of electron-withdrawing formyl moieties.

158 d for the preparation of 3,5-disubstituted 4-formyl-N-arylpyrazoles in a one-pot procedure is reporte

159 Competition binding using FPR1 ligands N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (Nle = Norleucine), formy

160 aturation binding with fluorescein-labeled N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys revealed ~2500 specific b

161 othesis, propofol inhibited the binding of N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys-fluorescein, a fluorescen

162 l protocol for the direct formation of alpha-formyl olefins employing common building blocks for orga

163 es is replaced with methyl-, hydroxymethyl-, formyl-, or carboxylcytosine.

164 an iridium-based catalyst designed to favor formyl over aromatic C-H activation.

165 N-Formyl peptide (fMLF) receptors (FPRs) are chemotactic r

166 at inflammation sites is partly driven by N-formyl peptide chemoattractant receptors (FPRs).

167 onistic peptides, including the host-derived formyl peptide MCT-ND4, we found that the PSMalpha pepti

168 PSMs exert their function by binding to the formyl peptide receptor (FPR) 2.

169 emotaxis, suggesting that this peptide binds formyl peptide receptor (FPR) 2.

170 an endogenous anti-inflammatory circuit via formyl peptide receptor (FPR) 2/lipoxin receptor (ALX) (

171 Innate immune chemoreceptors of the formyl peptide receptor (Fpr) family are expressed by vo

172 The formyl peptide receptor (Fpr) family is well known for i

173 G protein-coupled receptor belonging to the formyl peptide receptor (FPR) family, conveys the biolog

174 The formyl peptide receptor (FPR) on neutrophils, which bind

175 E neutrophils in a dose-dependent manner via formyl peptide receptor (FPR) stimulation.

176 -37pA induces calcium and chemotaxis through formyl peptide receptor (FPR)2/ALX, whereas its D-stereo

177 15-epi-LXA4 activated formyl peptide receptor (FPR2) and GPR120 on alternative

178 Our results demonstrate that formyl peptide receptor 1 (FPR1) and neutrophilic NADPH

179 Cys549, which then induces TRMP2 binding to formyl peptide receptor 1 (FPR1) and subsequent FPR1 int

180 Binding of formyl peptide receptor 1 (FPR1) by N-formyl peptides ca

181 Formyl peptide receptor 1 (FPR1) is a G protein-coupled

182 ceptor to be described on human neutrophils, formyl peptide receptor 1 (FPR1), is one such receptor t

183 osis by CXC chemokine receptor 2 (CXCR2) and formyl peptide receptor 1 (FPR1), respectively.

184 n jejunal cryosections with probes to detect formyl peptide receptor 1 (FPR1).

185 ted from wild-type mice and mice lacking the formyl peptide receptor 1, we demonstrate that LTB(4) ac

186 Activation of the G-protein coupled formyl peptide receptor 2 (ALX/FPR2) by the lipid mediat

187 Formyl peptide receptor 2 (FPR2) emerges as a central re

188 Annexin A1 (AnxA1) mainly acts through Formyl Peptide Receptor 2 (FPR2) inducing the resolution

189 Formyl peptide receptor 2 (FPR2) is a chemoattractant re

190 Formyl peptide receptor 2 (FPR2) is a G protein-coupled

191 Neutrophils expressing formyl peptide receptor 2 (FPR2) play key roles in host

192 The human formyl peptide receptor 2 (FPR2) plays a crucial role in

193 Selective agonists and antagonists of formyl peptide receptor 2 (Fpr2) suggested that Fpr2 med

194 timization of a peptidomimetic antagonist of formyl peptide receptor 2 (FPR2) was explored by an appr

195 Formyl peptide receptor 2 (FPR2), a classical chemoattra

196 nd SAA1 activated the SAA1-binding receptor, formyl peptide receptor 2 (FPR2), which drove the epithe

197 Here we report that formyl peptide receptor 2 (Fpr2/3) null mice display a m

198 ding and activation of the human and mouse N-formyl peptide receptor 2 (huFPR2).

199 Formyl peptide receptor 2 regulates monocyte recruitment

200 regulation of ALX/FPR2 (lipoxin A4 receptor/formyl peptide receptor 2) expression.

201 ceptor-2 (FPR2/ALX) and in mFPR2(-/-) (mouse formyl peptide receptor 2) mice lacking the mouse homolo

202 s by airway epithelial cells in an ALX/FPR2 (formyl peptide receptor 2) receptor-dependent manner.

203 roteins, namely protein phosphatase 5 (PP5), formyl peptide receptor 2, and annexin 1.

204 We investigated airway levels of formyl peptide receptor 2-lipoxin receptor (FPR2/ALXR),

205 as shown by experiments with DCs lacking the formyl peptide receptor 2.

206 ayed specific binding to the AnxA1 receptor (formyl peptide receptor 2/Lipoxin A4 receptor [FPR2/ALX]

207 Formyl peptide receptor 3 (Fpr3, also known as Fpr-rs1)

208 ey player in allergy to tropomyosins and the formyl peptide receptor 3 in allergy to lipocalins are o

209 iate these effects, whereas recognition by N-formyl peptide receptor family members was dispensable.

210 PR1) is a member of the chemotactic GPCR-7TM formyl peptide receptor family, whose principle function

211 ecognition and selectivity mechanisms of the formyl peptide receptor family.

212 s a noncanonical GRK that phosphorylated the formyl peptide receptor FPR1 and facilitated neutrophil

213 netic or pharmacological inhibition of the N-formyl peptide receptor Fpr1 leads to increased insulin

214 eins were previously reported to function as formyl peptide receptor inhibitors.

215 ed ERK and p38 MAPK signaling in response to formyl peptide receptor stimulation.

216 ulation and cAMP accumulation in response to formyl peptide receptor stimulation.

217 c peptide WKYMVm, a selective agonist of the formyl peptide receptor, a 2-fold increase in leukocyte

218 luminal casts depends on the high-affinity N-formyl peptide receptor, Fpr1.

219 These include the human formyl peptide receptor, human trace amine-associated re

220 (2+)-mobilizing G protein-coupled receptors (formyl peptide receptor, P2Y2 purinergic receptor, and c

221 out experiments to study the capacity of the formyl peptide receptor-1 (FPR1) to desensitize chemokin

222 tein B1 (HMGB1), respectively, as well as to formyl peptide receptor-1 (FPR1), which interacts with A

223 LL-37, via formyl peptide receptor-2 (FPR-2), triggered the release

224 ocortin-4 receptor, the Smoothened receptor, formyl peptide receptor-2 (FPR2), the relaxin receptor (

225 ll interfering RNA-induced knockdown of LXA4 formyl peptide receptor-2 (FPR2/ALX) and in mFPR2(-/-) (

226 drial ATP production and requires an initial formyl peptide receptor-induced Ca(2+) signal that trigg

227 nctions of cathelicidin are mediated through formyl peptide receptor-like 1 (FPRL1), we hypothesize t

228 ith WRW4, an antagonist of the transmembrane formyl peptide receptor-like 1 protein attenuated LL-37'

229 RvD1, by activating its receptor formyl peptide receptor2/lipoxin A4 receptor, suppresses

230 Mouse neutrophils lacking formyl peptide receptors (Fpr1/2(-/-)) are defective in

231 N-formyl peptide receptors (FPRs) are critical regulators

232 Formyl peptide receptors (FPRs) are G-protein-coupled re

233 r current work showed that G-protein-coupled formyl peptide receptors (FPRs) directly mediate neutrop

234 N-formyl peptide receptors (FPRs) serve as phagocyte patte

235 class of such receptor-ligand pairs involves formyl peptide receptors (FPRs) that have been shown to

236 ed a significant difference in expression of formyl peptide receptors (FPRs).

237 te ERK pathway activity via interaction with formyl peptide receptors (FPRs).

238 cquisition of neuronal specificity by immune formyl peptide receptors (Fprs).

239 sion of mRNAs for annexin A1 (AnxA1) and the formyl peptide receptors [(Fprs) 1, 2, and 3], a loss of

240 Stimulation of formyl peptide receptors increases the mitochondrial mem

241 The neutrophil formyl peptide receptors, FPR1 and FPR2, play critical r

242 testinal levels of the microbiota-produced N-formyl peptide, formyl-methionyl-leucyl-phenylalanine, a

243 hat LTB(4) production dramatically amplifies formyl peptide-mediated neutrophil polarization and chem

244 Mice inoculated with the formyl peptide-producing wild-type strain showed a signi

245 Endothelial-bound cathelicidin activates formyl-peptide receptor 2 on classical monocytes, result

246 Here we tested whether the formyl-peptide receptor 2/3 (Fpr2/3)--ortholog to human

247 e, we tested whether the lipoxin A4 receptor formyl-peptide receptor 2/3 (Fpr2/3; ortholog to human F

248 Formyl-peptide receptor type 2 (FPR2), also called ALX (

249 Formyl-peptide receptor type 2 (FPR2; also called ALX be

250 rophils, but not nonclassical monocytes in a formyl-peptide receptor-dependent manner.

251 Formyl-peptide receptors (FPRs) are important pattern re

252 Formyl-peptide receptors are highly expressed on neutrop

253 Chemokines and mitochondrial products (e.g., formyl peptides and mitDNA) collaborate in neutrophil-me

254 Although several N-formyl peptides are known to bind to these receptors, mo

255 ing of formyl peptide receptor 1 (FPR1) by N-formyl peptides can activate neutrophils and may represe

256 dient of chemokines and mitochondria-derived formyl peptides collaborate to guide neutrophils to site

257 ancy of these G-protein-coupled receptors by formyl peptides has been shown to induce regulatory phos

258 Considering the importance of N-formyl peptides in inflammatory processes, our data indi

259 tor sensory neurons-detect bacterial toxins, formyl peptides, and lipopolysaccharides through distinc

260 response to primary chemoattractants such as formyl peptides, is important in initiating the inflamma

261 quisitely regulates neutrophil chemotaxis to formyl peptides, which are produced at the core of infla

262 le in neutrophil activation and migration to formyl peptides.

263 fine binding affinity and agonist potency of formyl peptides.

264 The presence of the lipoxin A4 receptor/formyl peptidyl receptor (ALX/FPR) in KS patient tissue

265 enylnitrene was generated by photolysis of 2-formyl phenylazide isolated in Ar, Kr, and Xe matrixes a

266 Triplet 2-formyl phenylnitrene was generated by photolysis of 2-fo

267 or 2,5-dihydrofuran yields some of the beta-formyl product.

268 The identification of N-formyl-protected glycine as the ligand (Formyl-Gly-OH) w

269 tween the phosphoryl oxygen and the aldehyde formyl proton present in TADDOL-derived catalysts.

270 and the phosphoryl oxygen interacts with the formyl proton.

271 is method involves the Ugi-4CR of 2-chloro-3-formyl quinolines 1a-h, amines 2a-d, 2-chloroacetic acid

272 The formyl-radical equivalent then undergoes nickel-catalyze

273 report the first direct catalytic method for formyl-selective deuterium labeling of aromatic aldehyde

274 itions with PhSiH3 , an observable magnesium formyl species may be intercepted for the mild reductive

275 e kinetics and mechanism of the reactions of formyl-stabilized ylide Ph3P horizontal lineCHCHO (1) an

276 Formyl-substituted aryl and heteroaryl MIDA boronates we

277 egy toward the production of a wide range of formyl-substituted rings with alkene transposition.

278 These formyl substitution derivatives exhibit different spectr

279 t different spectral shifts according to the formyl substitution position.

280 etic intermediate, was proposed to signal 10-formyl-tetrahydrofolate (10f-THF) deficiency in bacteria

281 ZTP, a signal of 10-formyl-tetrahydrofolate (10f-THF) deficiency in bacteria

282 al one-carbon metabolism intermediate, N(10)-formyl-tetrahydrofolate (N(10)-CHO-THF).

283 xidation of methylene tetrahydrofolate to 10-formyl-tetrahydrofolate is coupled to reduction of NADP(

284 ne encodes a mitochondrial monofunctional 10-formyl-tetrahydrofolate synthetase, termed MTHFD1L.

285 metabolism revealed complete oxidation of 10-formyl-tetrahydrofolate to make NADPH.

286 ired for the stimulation of germ cells by 10-formyl-tetrahydrofolate-Glun and dihydropteroate.

287 proliferation is stimulated by the folate 10-formyl-tetrahydrofolate-Glun both in vitro and in animal

288 based formulas contained polyglutamates of 5-formyl-tetrahydrofolate.

289 and reduced folates (THF + 5-methyl-THF + 5-formyl-THF + 5,10-methenyl-THF; R2 = 0.01, P = 0.02), re

290 of one-carbon groups for the synthesis of 10-formyl-THF and other one-carbon intermediates; these are

291 es that in the absence of ALDH1L1 enzyme, 10-formyl-THF cannot be efficiently metabolized in the live

292 pX first transfers the formyl group of N(10)-formyl-THF to produce formyl-coenzyme A (formyl-CoA) as

293 sed of an N-terminal module similar to N(10)-formyl-THF transferases and a C-terminal module homologo

294 lar [(3)H]THF cofactors derived from [(3)H]5-formyl-THF were depleted in R5 cells compared with those

295 CO using N(10)-formyltetrahydrofolate (N(10)-formyl-THF) as the substrate.

296 milk tetrahydrofolate (THF), 5-methyl-THF, 5-formyl-THF, 5,10-methenyl-THF, and UMFA were measured wi

297 and tetrahydrofolate (THF), 5-methyl-THF, 5-formyl-THF, 5,10-methenyl-THF, and unmetabolized folic a

298 dria to cytoplasm, producing formate from 10-formyl-THF.

299 Herein, we report that heptamer formyl thiophene acetic acid (hFTAA) passes the blood-br

300 ioselective construction of enolizable alpha-formyl vinylic stereocenters without racemization or ole