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1  indicated that the amino group of Val226 is formylated.
2 ine (5mC) into its hydroxymethylated (5hmC), formylated (5fC), or carboxylated (5caC) forms.
3 gomeric ethers were found to function as the formylating agent, with 1,4-dioxane affording the best r
4  carboxylic acid ester group and DMSO as the formylating agent.
5 ages, mixed amine/imine bonds, and partially formylated amine linkages are obtained in a single step
6 eaction was the use of iron pentacarbonyl to formylate an aryllithium when DMF and methyl formate pro
7 n (S5 and S27 also appeared to be internally formylated and acetylated, respectively).
8 a-toxin accumulated in the culture medium in formylated and deformylated forms.
9 tion/hydrolysis and furnishing mixtures of N-formylated and unformylated amino acid derivatives.
10               alpha,beta-Unsaturated imides, formylated at the nitrogen atom, comprise a new and valu
11  receptors that respond to proinflammatory N-formylated bacterial peptides (e.g., formyl-Met-Leu-Phe,
12 id expansion of CD8+ T cells by presenting N-formylated bacterial peptides.
13 bsequent superoxide release triggered by the formylated bacterial tripeptide formyl-Met-Leu-Phe, and
14 onjugated BODIPYs in high yields by treating formylated BODIPYs with alkyl/aryl ylides under simple r
15 vector, the levels of PDF were increased and formylated BST was undetectable.
16 hmtRNA(Met) that can be aminoacylated is not formylated by the mitochondrial Met-tRNA transformylase
17 , G-protein-coupled phagocyte receptor for N-formylated chemotactic peptides, formyl peptide receptor
18                            In contrast, only formylated delta-toxin accumulated after the early poste
19 ncides with the transition to producing only formylated delta-toxin and results in an increased infla
20 nd neutrophil chemotactic activity only with formylated delta-toxin.
21 sequent reactions of aminonitriles and their formylated derivatives in formamide.
22 rried out to account for the behavior of the formylated derivatives.
23 ptide deformylase has been developed using a formylated dipeptide, formyl-Met-Leu-p-nitroanilide, as
24 isplays Michaelis-Menten kinetics toward the formylated dipeptide, with K(M) = 20.3 +/- 1.3 microM, k
25   Strikingly, the amino group of GAR that is formylated during the reaction lies at 2.8 A from one of
26 lic alcohol moieties were obtained from beta-formylated enoates and terminal alkynes.
27 gh M3-restricted CTLs preferably recognize N-formylated epitopes, i.e., those of mitochondrial or pro
28 that 5-formylTHF is a storage form of excess formylated folates in mammalian cells.
29                                 Existence of formylated folates in RBCs only from individuals with th
30                A portion of Met-tRNA(Met) is formylated for initiation, whereas the remainder is used
31 ral membrane glycosyltransferase, attaches a formylated form of aminoarabinose to the lipid undecapre
32 omolar concentrations of an amino-terminal N-formylated hexapeptide, fMIGWII, targeted cells for lysi
33 ially available pyrazoles were alkylated and formylated in a regiocontrolled manner to give pyrazole-
34 e initiator tRNA is aminoacylated but is not formylated in H. volcanii.
35                       This compound was then formylated in the 6-position.
36  dithienyl-borondipyrromethene (BODIPY) dyes formylated in the beta'-position (2b, 2c) have been trea
37       In contrast, the initiator Met-tRNA is formylated in the respective "wild-type" parental strain
38                                  A series of formylated indazoles and carboxylic acid esters of indaz
39 acteria, can at least to some extent utilize formylated initiator Met-tRNA to initiate protein synthe
40                    We show that oxidation of formylated initiator methionines is detrimental in part
41 chloroplasts is widely believed to require a formylated initiator methionyl tRNA (fMet-tRNA(fMet)) fo
42 itochondria and chloroplasts normally uses a formylated initiator methionyl-tRNA (fMet-tRNA(f)(Met)).
43 chloroplasts is widely believed to require a formylated initiator methionyl-tRNA (fMet-tRNAfMet) in a
44 erevisiae were synthesized in the absence of formylated initiator tRNA.
45                                              Formylated Met-Leu-Phe (fMLF) is shown to stimulate a ra
46 hils stimulated with the chemotactic peptide formylated Met-Leu-Phe (fMLP) demonstrated transient PS
47 ynthetic respiratory defect in cells lacking formylated Met-tRNA(f)(Met) due to loss of the MIS1 gene
48 s accessory factor might be unnecessary when formylated Met-tRNA(f)(Met) is present but becomes essen
49  the pattern did not change in cells lacking formylated Met-tRNAfMet.
50         One mitochondria-derived immunogenic formylated metabolite we identified is 5-formyl-deoxyuri
51 le for detection of short peptides bearing N-formylated methionine (fMet) that are characteristic of
52  protein synthesis in bacteria begins with a formylated methionine, the formyl group of the nascent p
53 , where new peptides are initiated with an N-formylated methionine.
54 ted peptides and higher affinities than some formylated mitochondrial peptides.
55 90; MLIIWG; MLIIWGV; and MLIIWGI, as well as formylated MLIIW.
56 ophages effectively, suggesting that these N-formylated Mtb peptides are presented as the naturally p
57 ungs, spleen, and lymph nodes responded to N-formylated Mtb peptides in an M3-restricted manner.
58                                Four of the N-formylated Mtb peptides were able to elicit cytotoxic T
59 id polypeptide secreted predominantly with a formylated N-terminal methionine, which led us to invest
60 the origin of the enzyme's specificity for N-formylated over N-acetylated substrates.
61        J774 cells did not migrate toward the formylated peptide (fMet-Leu-Phe; fMLF), and chemotaxis
62 is that an interaction with the receptor for formylated peptide (FPR), so far reported only in vitro,
63  'antibiotic-chemoattractants', consist of a formylated peptide (known to act as chemoattractant for
64      Pseudopod growth was stimulated using N-formylated peptide (N-formyl-methionyl-leucyl-phenylalan
65                     The lack of endogenous N-formylated peptide allows discovery of novel pathogen-de
66 ed T-cell response is T cells that recognize formylated peptide antigens presented by M3 molecules.
67             We now present evidence that the formylated peptide f-Met-Leu-Phe (fMLP), a bacterial che
68 tion enhances the neutrophil response to the formylated peptide FMLF, leading to increased reactive o
69 d whether hPepT1 could transport the model n-formylated peptide fMLP and, if so, whether such cellula
70 tors; the systemic administration of Boc2, a formylated peptide receptor (fpr) antagonist, abrogated
71  contribution from P2'and P3' positions of a formylated peptide substrate to turnover.
72 rified deformylase is highly active toward N-formylated peptide substrates.
73 n response to tumor necrosis factor (TNF) or formylated peptide.
74                                              Formylated peptides (e.g. n-formyl-Met-Leu-Phe (fMLP)) a
75  by prior exposure to the chemoattractants N-formylated peptides (fMLP) or a complement cleavage prod
76 mponent of the bacterial outer membrane, and formylated peptides (fMLP), a bacterial-derived peptide,
77 the fifth component of complement (C5a) or n-formylated peptides (formylmethionylleucylphenylalanine,
78 lls with cDNAs encoding receptors for either formylated peptides (FR), a product of the fifth compone
79 ptors for platelet-activating factor (PAFR), formylated peptides (FR), or interleukin-8 (CXCR1) were
80 Ps), such as mitochondrial DNA (mtDNA) and N-formylated peptides (NFPs), are elevated in patients who
81  nociceptor neurons, in part via bacterial N-formylated peptides and the pore-forming toxin alpha-hae
82                                    Bacterial formylated peptides are important chemotactic molecules
83 de deformylase using a series of synthetic N-formylated peptides as substrates.
84                                   Endogenous formylated peptides can come from the N-terminus of each
85 eptors (FPRs) mediate pattern recognition of formylated peptides derived from invading pathogens or m
86                             Although three N-formylated peptides derived from L. monocytogenes are kn
87 omplex (MHC) class Ib molecule H2-M3 binds N-formylated peptides from mitochondria and bacteria.
88  cell surface by addition of high-affinity N-formylated peptides from mitochondria and listeria.
89                           Our data show that formylated peptides function as important virulence fact
90                        Given the presence of formylated peptides in bacteria and mitochondria, possib
91                                  The role of formylated peptides in S. aureus infections has been unk
92 involved in a signaling pathway triggered by formylated peptides leading to the selective activation
93 whereas tapasin is critical for loading of N-formylated peptides onto the intracellular pool of M3.
94                                              Formylated peptides produced as a byproduct of bacterial
95 s Ib molecule that preferentially presents N-formylated peptides to CD8(+) T cells.
96       MHC class Ib molecule H2-M3 presents N-formylated peptides to CD8+ CTLs.
97 ty complex class Ib molecule that presents N-formylated peptides to cytotoxic T cells.
98  However, the signaling pathway triggered by formylated peptides to integrin activation and leukocyte
99                                Addition of N-formylated peptides to TAP(o) cells stabilizes M3 in the
100 s that appeared to be involved in binding of formylated peptides were located at sites analogous to t
101 T cells, which recognize short hydrophobic N-formylated peptides, appear to comprise a substantial po
102 ng both mitochondrial- and bacterial-derived formylated peptides, including the PSMalpha toxins secre
103                 Upon addition of exogenous N-formylated peptides, M3 trafficks rapidly to the cell su
104 to the classic bacterial chemoattractants, n-formylated peptides, or other soluble bacterial factors.
105 chemokines, such as interleukin-8, bacterial formylated peptides, platelet-activating factor, leukotr
106 n is catalytically active in deformylating N-formylated peptides, shares many of the properties of ba
107       Recent reports have indicated that non-formylated peptides, such as MMWLL can also activate thi
108                           Blood amounts of N-formylated peptides, which are endogenous agonists of FP
109  of the mouse with a unique preference for N-formylated peptides, which may come from the N-termini o
110  phenol-soluble modulins (PSMs), which are N-formylated peptides.
111 in (Deltafmt) lacking the ability to produce formylated peptides.
112 e in degrading bacterial and mitochondrial N-formylated peptides.
113 release pro-inflammatory molecules including formylated peptides.
114 in-deficient mice, even in the presence of N-formylated peptides.
115 Ib molecule with a high propensity to bind N-formylated peptides.
116 xin A4 receptor, a low affinity receptor for formylated peptides; and 4) either highly conserved or d
117 of HMTA, the method offers easy access to di-formylated phenols as well.
118 covalent thiohemiacetal was formed between a formylated phosphotyrosine analog and the thiol side cha
119                                        The 3-formylated product was reduced to the 3-methyl derivativ
120 cell folate and was inversely related to the formylated proportion of red blood cell folates (P < 0.0
121  previously unreported) accumulation of an N-formylated protein species.
122                                          The formylated resorcinarene reacts easily with primary alip
123 binding peptides representing the N-terminal formylated sequences from five Cpn Ags sensitized target
124                                 N-terminally formylated signal peptide fragments with variable sequen
125 in the mitochondria, along with its putative formylated substrates; however, the cellular function of
126                         The structure of the formylated sugar nucleotide generated in vitro by ArnA w
127         We further demonstrate that only the formylated sugar nucleotide is converted in vitro to an
128 n was found as manifested by the presence of formylated tetrahydrofolate polyglutamates in addition t
129 rary that contains all possible N-terminally formylated tetrapeptides was constructed on TentaGel res
130 in amine of ornithine, which is subsequently formylated to generate the iron-chelating hydroxamates o
131  neutrophil chemoattractants, particularly N-formylated tripeptides and possibly leukotriene B(4) and
132 ding neutrophil chemotactic agents such as N-formylated tripeptides, have all been refuted by recent
133 , as well as the low relative affinity for N-formylated tripeptides, suggest that neither the copurif
134       Neither ligand is displaced by added N-formylated tripeptides.
135               In the first step the amine is formylated via an in situ formed alkylammonium formate s
136 In addition, the [alpha-(32)P]UDP-l-Ara4N is formylated when N-10-formyltetrahydrofolate is included.

 
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