ライフサイエンスコーパス: fornix

1 he mammillary bodies via the postcommissural fornix.

2 host phenotype (vaginal pH) in the posterior fornix.

3 wab was taken from the inferior conjunctival fornix.

4 lengths of remyelinated nerve fibers in the fornix.

5 was collected from the inferior conjunctival fornix.

6 oro-parietal regions as well as splenium and fornix.

7 iscs remain for at least 1 hour in the lower fornix.

8 peared to be related to abnormalities of the fornix.

9 ng of such associations also depended on the fornix.

10 selectively disrupted by transection of the fornix.

11 ese cortical inputs were less reliant on the fornix.

12 al inputs to the hippocampus via the fimbria-fornix.

13 ron, had a main axon that coursed toward the fornix.

14 ll as to the ipsilateral hippocampus via the fornix.

15 gion lateral to the descending column of the fornix.

16 lowing unilateral transection of the fimbria fornix.

17 is, or unilateral transection of the fimbria fornix.

18 tory gating following lesions of the fimbria-fornix.

19 paration containing the MS-DB and the dorsal fornix.

20 ngth of the palpebral conjunctiva toward the fornix.

21 um 3 weeks before transection of the fimbria fornix.

22 matically in the corpus callosum and fimbria/fornix.

23 expressing purulent fluid into the superior fornix.

24 normalities of the septum pellucidum and the fornix.

25 ions of limbic fiber pathways, including the fornix.

26 ale sex (35% vs 49%, P < .0001), location in fornix (2% vs 6%, P = .0016) and tarsus (1% vs 4%, P = .

27 M. E. Bouton, who found that lesions of the fornix abolished reinstatement of aversively conditioned

28 t-lid technique, a procedural improvement if fornix access is difficult.

29 Low-frequency stimulation of the fornix activates the hippocampus and other areas of the

30 Although damage to the human fornix also results in memory impairment, it is not know

31 Finally, both the fornix and anterior thalamic lesions severely impaired T

32 utaneous junction of the eyelid, through the fornix and bulbar conjunctiva.

33 le changes in the limbic system, such as the fornix and cingulum.

34 mplanted with an electrode into the proximal fornix and dorsal hippocampal commissure on the language

35 Fornix and hippocampal differences were both associated

36 re used to analyze the relationships between fornix and hippocampal measures and their predictive pow

37 The fornix and hippocampus are critical to recollection in t

38 43 labelled fibers in terminal fields, i.e., fornix and hippocampus, that were not observed in contro

39 t sections located in the ipsilateral dorsal fornix and in the contralateral parahippocampal white ma

40 athology in a number of tracts including the fornix and increased structural connectivity between the

41 fornix microstructure and the other on both fornix and left PHC.

42 and a second limbic connection following the fornix and the anterior limb of the internal capsule.

43 ences between anatomical regions such as the fornix and the cingulum bundle or corpus callosum.

44 t glia but not neurite density damage in the fornix and the hippocampus.

45 Furthermore, as the volumes of the left fornix and the left mammillary bodies decreased, the dif

46 st that degradation of microstructure in the fornix and the uncinate fasciculus make critical but dif

47 iation tracts such as the anterior cingulum, fornix and uncinate fasciculus.

48 ip between microstructural properties of the fornix and variation in Body Mass Index (BMI), within no

49 ociated with memory loss when accompanied by fornix and/or mammillary body atrophy.

50 laris, radiofrequency lesions of the fimbria-fornix, and aspiration lesions of the frontal cortex on

51 gions including the corpus callosum, fimbria/fornix, and cerebellar deep white matter.

52 al cortices, the corpus callosum and fimbria/fornix, and cerebellar white matter.

53 Tear wash fluid was collected from inferior fornix, and conjunctival epithelium was obtained by impr

54 at involved the body of the corpus callosum, fornix, and main anterior-posterior pathways (P < .05).

55 g the inferior temporal cortex, hippocampus, fornix, and mammillary bodies.

56 sity of oligodendrocytes in corpus callosum, fornix, and spinal cord is 20-40% greater in males compa

57 r FA were found in the hippocampal cingulum, fornix, and stria terminalis, posterior corona radiata,

58 n all divisions of the corpus callosum, left fornix, and subgenual cingulum compared with control sub

59 reas: superior and inferior areas of bulbus, fornix, and tarsus of male Sprague-Dawley rats (n = 6).

60 structures, namely, the uncinate fasciculus, fornix, and ventral prefrontal tract, showed structural

61 ural alterations in the uncinate fasciculus, fornix, and ventral prefrontal tract: tracts that connec

62 To compare effectiveness of fornix- and limbal-based conjunctival flaps in trabecule

63 n the initial acquisition stage, control and fornix animals were equally proficient in learning the d

64 ion sub-scores to FA values in the cingulum, fornix, anterior commissure, corpus callosum and right u

65 spatial statistics suggested the crus of the fornix as a focus for this relationship.

66 nhuman primates, critically highlighting the fornix as a source of interindividual variation in scene

67 ssion of the gel-forming mucin begins at the fornix at 7 days after birth and is correlated with the

68 ent amplifying cells that migrate toward the fornix at a rate of approximately 1.7 mm/d with a transi

69 , can also prevent the loss of these fimbria fornix axotomised cholinergic neurons, where GM1 alone d

70 In the fornix-based and limbal-based surgery, mean IOP at 12 mo

71 ng controversies such as limbus-based versus fornix-based approaches to trabeculectomy and one-site v

72 oped bleb leaks significantly later than did fornix-based cases (2.1 vs. 1.0 years; P=0.002, GEE mode

73 eriod after surgery (P=0.02, Cox model), and fornix-based cases requiring cataract surgery had the op

74 to failure for postoperative IOP control vs fornix-based incision.

75 Eyes undergoing the fornix-based operation had a greater risk of cataract su

76 all available follow-up was more common with fornix-based operations (P=0.01, GEE model).

77 ased operations during the first 4 years and fornix-based operations during the last 4 years.

78 leaks within 4 years after both limbus- and fornix-based operations; however, limbus-based cases dev

79 Fornix-based procedures have more symptomatic hypotony a

80 rgery, the success rates of limbus-based and fornix-based trabeculectomy were not statistically diffe

81 s rates are similar between limbus-based and fornix-based trabeculectomy.

82 owing no difference in effectiveness between fornix-based vs limbal-based trabeculectomy surgery, alt

83 asses were identified in the upper and lower fornix bilaterally and involved the tarsus of the right

84 Axial diffusivity was increased in the fornix bilaterally and right dorsal-anterior cingulum.

85 Fornix body volume and axial diffusivity were highly sig

86 ed change in the cross-sectional area of the fornix, but there is a significant loss of myelinated ne

87 Deepening of the inferior fornix by removing degenerated Tenon's and reconstructio

88 iour in the white matter tracts of interest (fornix, cingulum and corpus callosum).

89 ded the splenium of the corpus callosum, the fornix, cingulum, and superior and inferior longitudinal

90 call tasks in patients with anomalies of the fornix compared with those without (P = .04, exact two-t

91 Incisional biopsy specimens of ventral fornix conjunctiva were collected before gland removal (

92 mic-prefrontal interactions, mediated by the fornix, contribute to the healthy functioning of network

93 superior longitudinal fasciculus, bilateral fornix (cres)/stria terminalis, genu and splenium of the

94 enu, thalamus, right posterior cingulum, and fornix crus (seven studies; largest cluster, 980 voxels;

95 ferior fronto-occipital fasciculus, and left fornix crus (six studies; 323 voxels; z = 1.7; P = .001)

96 2]) and tracts involved in limbic circuitry (fornix crus [AD, beta = 0.02 (P = .046)] and cingulum [R

97 In the presence of fornix damage in mild cognitive impairment (MCI), a reco

98 s were found between the apparent effects of fornix damage in these clinical cases and those observed

99 These findings not only indicate that fornix damage is sufficient to induce anterograde amnesi

100 ammillary body volume (which atrophies after fornix damage).

101 ontinuing until p28, the ipsilateral fimbria fornix degenerates.

102 ould be among the first studies establishing fornix degeneration as a predictor of incipient cognitiv

103 Fornix degeneration is a feature of aging and Alzheimer'

104 ory for scenes presented on touch screens is fornix dependent.

105 An FICD modification of a custom-designed fornix depth measurer (FDM) was validated and used for m

106 o provide normative data for upper and lower fornix depths (FDs) and fornix intercanthal distance (FI

107 epto-hippocampal glutamatergic fibers in the fornix did not have an effect.

108 Lesions of the fimbria-fornix disrupt auditory gating by preventing cholinergic

109 The fornix does not show the abnormalities in cross-sectiona

110 For 50% of the trials, the fornix electrode was continuously stimulated using a bur

111 PSPMNs located around the fornix express orexin, whereas those located around the

112 ween MS patients and controls were found for fornix FA (0.38 vs. 0.46, means adjusted for age and for

113 Multivariate regression analysis identified fornix FA and mammillary bodies as predictor of visual r

114 n status (P = 0.032) significantly predicted fornix FA.

115 In contrast, lesions of the fornix facilitate acquisition on this task, showing that

116 imately 100 msec duration) evoked by fimbria/fornix (FF) stimulation in a majority of neurons tested.

117 ed controls along the left and right fimbria-fornix (FF), parahippocampal WM bundle (PWMB), arcuate f

118 c nuclei (ATN) or transection of the fimbria-fornix (FF).

119 ls received a complete lesion of the fimbria-fornix (FF).

120 ts demonstrate the importance of the fimbria-fornix fiber system in spatial short-term memory but sug

121 PARA) or electrolytic lesions of the fimbria-fornix (FNX) and were tested for their (a) discriminatio

122 fimbria and the CA1 efferents via the dorsal fornix for encoding and consolidation/retrieval of class

123 rnix regions-of-interest were used to derive fornix fractional anisotropy (FA).

124 g the mammillary bodies: the postcommissural fornix from the hippocampal formation and Gudden's ventr

125 They run along the fornix from the hypothalamus, along the supraoptic decus

126 causing gray matter decline; controlling for fornix glia damage, the correlations between age and hip

127 status than was cross-sectional area of the fornix, global mean white-matter FA and left frontal lob

128 Transection of the nonhuman primate fornix has been shown to impair learning of configuratio

129 the later stages of decline, the ability of fornix-hippocampal markers to predict the earliest clini

130 o the magnocellular mediodorsal thalamus and fornix impaired postoperative retention of the preoperat

131 ated memory decline: the hippocampus and the fornix in 166 asymptomatic individuals (aged 38-71 years

132 otic membrane resulted in achieving a deeper fornix in 83% of patients with various cicatrizing conju

133 in 23 (72%), bulbar conjunctiva in 31 (97%), fornix in 9 (28%), tarsus in 3 (9%), semilunar fold in 1

134 GMS drops were retained in the inferior fornix in all animals for the length of the study.

135 store the tear meniscus, but also deepen the fornix in CCh patients.

136 ports the idea that the main function of the fornix in macaque monkeys is to support new learning abo

137 The precise involvement of the fornix in memory, however, has been difficult to ascerta

138 for a role beyond the spatial domain for the fornix in monkeys.

139 e matter bundle, and the ipsilateral fimbria-fornix in regions located within the medial temporal lob

140 in the white matter, and specifically in the fornix, in humans and rats.

141 The fornix, in turn, may display alterations in microstructu

142 ssment; no studies were found that evaluated fornix incisions.

143 terned electrical stimulation of the fimbria-fornix increased TGC in amnestic animals and partially r

144 mice received weekly periocular conjunctival fornix injections of a dexamethasone-21-acetate (DEX-Ac)

145 for recall, there was a significant group x fornix interaction, indicating that the association betw

146 for upper and lower fornix depths (FDs) and fornix intercanthal distance (FICD) within a healthy Sou

147 ncle (corticospinal tract), corpus callosum, fornix, internal capsule (thalamocortical and corticotha

148 The fornix is a major pathway through which neurons project

149 y demonstrated that burst stimulation of the fornix is able to significantly improve memory in a rode

150 whether the fiber number or structure of the fornix is abnormal in schizophrenia, as was suggested by

151 mpairment in monkeys with transection of the fornix is exacerbated by prior depletion of acetylcholin

152 Decreased FA in of the columns of the fornix is particularly robust in early FAD and may provi

153 The fornix is the main tract between the medial temporal lob

154 lts suggest that one specialized role of the fornix is to process temporal information.

155 Transection of the fimbria fornix leads to retrograde degeneration of axotomised se

156 fferences were also found in the body of the fornix, left fimbria, and superior longitudinal fascicul

157 behavioral arrest could be reconstituted in fornix-lesioned animals by inducing synchronous activity

158 of auditory gating by DMXB-A in the fimbria-fornix-lesioned rats was blocked by intracerebroventricu

159 XB-A restored auditory gating in the fimbria-fornix-lesioned rats, indicating that activation of the

160 ctions of 192 IgG-saporin (SAP-HPC), fimbria-fornix lesions (FF), or sham control surgeries were test

161 hippocampal physiology compared with fimbria-fornix lesions and septal inactivation, we observed limi

162 raining rabbits (Oryctolagus cuniculus) with fornix lesions concurrently on two discrimination tasks

163 Fornix lesions did not affect either version of the task

164 Rats with fornix lesions had normal baseline levels of hippocampal

165 During the same task, rats with fornix lesions learned to approach a visible platform bu

166 The results further imply that fornix lesions may impair memory in part by decoupling n

167 Moreover, fornix lesions need not mimic the effects of direct dama

168 Rats with fornix lesions performed well on the VPC task but were i

169 arning and memory, the results obtained with fornix lesions suggest that ACh release in the hippocamp

170 induction of Arc transcription in rats with fornix lesions that impair hippocampal learning yet leav

171 Rats with anterior thalamic lesions and fornix lesions were unimpaired on a configural learning

172 This induction is blocked by fornix lesions, which are known to disrupt activation of

173 ated regions, not seen after postcommissural fornix lesions.

174 l synaptic potentiation and Arc in rats with fornix lesions.

175 erformed a spatial task that was impaired by fornix lesions.

176 ian patient age (50 vs 61 years, P < .0001), fornix location (32% vs 54%, P < .0001), larger median b

177 eys by lesions restricted to the hippocampus-fornix-mamillary system.

178 suggests that theta burst stimulation of the fornix may be associated with improvement in visual-spat

179 Fornix MD and f measures correlated with scene, but not

180 ne among normal elderly individuals and that fornix measures would be associated with gray matter cha

181 e also observed associations between ILF and fornix microstructure and category-selective BOLD respon

182 there was no significant correlation between fornix microstructure and familiarity memory or performa

183 account for recall performance: one based on fornix microstructure and the other on both fornix and l

184 specifically associated with degradation of fornix microstructure, consistent with the view that thi

185 plore whether theta burst stimulation of the fornix might improve memory in humans.

186 In tests of AN (experiment 3), fornix monkeys performed at the same level as control an

187 WSR and BSR were intermixed (experiment 1), fornix monkeys performed below the level of the control

188 In experiment 2, fornix monkeys were significantly impaired on tests of B

189 Low-frequency stimulation of the fornix occurred in 4-hour sessions in the video-electroe

190 me fraction, f) were then extracted from the fornix of each participant, which had been reconstructed

191 Tear fluid was collected from the inferior fornix of normal subjects (n = 17) and patients with Sjo

192 before use of povidone iodine; the inferior fornix of the fellow eye was also cultured and served as

193 At the time of enrollment, the inferior fornix of the treated eye was swept with a culture swab

194 fluoride dosimeters both into the posterior fornix of the vagina and on the skin at the beam entranc

195 atal DES exposure downregulated RUNX1 in the fornix of the vagina, where DES-associated adenosis is f

196 ross-sectional electron micrographs from the fornix of young and old rhesus monkeys using a semi-auto

197 lms collected from the inferior conjunctival fornix or bulbar conjunctiva.

198 rtical acetylcholine after the lesion of the fornix or mammillary bodies did not increase the severit

199 Animals with lesions of the fornix or perirhinal-entorhinal cortex acquired at least

200 the deficit is equivalent in magnitude after fornix or perirhinal-entorhinal damage.

201 e caruncle, but rarely are nevi found in the fornix or tarsal conjunctival surface.

202 onic stimulation of the subthalamic nucleus, fornix, or hippocampus may be effective in attenuating s

203 area; some were on the palpebral side of the fornix; others were present on the bulbar side.

204 s obtained from different locations (cervix, fornix, outer vaginal canal) and by different methods (s

205 We also found that FA in the columns of the fornix (P = 0.008) and left orbitofrontal lobe white mat

206 ter FA (P = 0.045), FA of the columns of the fornix (P = 0.012), area of the perforant pathways bilat

207 From preoperative imaging, the fimbria-fornix, parahippocampal white matter bundle and uncinate

208 itant theta burst stimulation of the fimbria-fornix pathway.

209 and greater microstructural integrity of its fornix pathway.

210 ith larger axial and mean diffusivity in the fornix (r = 0.64 and r = 0.55 respectively), relationshi

211 The tear reservoir in the fornix rapidly replenishes the meniscus under normal cir

212 All patients underwent COMET, with an aim of fornix reconstruction and visual rehabilitation.

213 raoperative adjunction of mitomycin C during fornix reconstruction with amniotic membrane resulted in

214 thesis that low-frequency stimulation of the fornix reduces interictal epileptiform discharges and se

215 overlying mucosal lymphoid follicles in the fornix region.

216 Manual fornix regions-of-interest were used to derive fornix fr

217 ial task, and existing direct evidence for a fornix role in spatial memory comes exclusively from tas

218 emporal cortex, with the later addition of a fornix section ipsilateral to the MFB lesion.

219 rmation and its connections including CA1-4, fornix, septal nuclei, hippocampal commissure, septohipp

220 hibition of wound contraction (6.8% +/- 3.2% fornix shortening) and the formation of a tissue that re

221 ds had closed by contraction (26.4% +/- 5.0% fornix shortening) and the formation of scarlike tissue

222 er FW and lower fractional anisotropy in the fornix showed a stronger association with memory impairm

223 osed with chronic domoic acid toxicosis, the fornix showed signs of altered diffusion properties indi

224 ampal projections, which coursed through the fornix, showed a rostrocaudal gradient as more arose in

225 Fornix status was assessed directly by overall volume an

226 rkably, artificial hPAC generated by fimbria-fornix stimulation during recall of a learned avoidance

227 Fornix stimulation elicited evoked responses in the hipp

228 their projections to the hippocampus through fornix stimulations had no effect on theta rhythms, sugg

229 rential effects on the hippocampal cingulum, fornix, stria terminalis, posterior corona radiata, and

230 ecuneus, hippocampus, amygdala, caudate, and fornix/stria terminals.

231 ting that the association between recall and fornix structure was weaker in patients.

232 The terms giant fornix syndrome, senile sunken upper lids, and prostagla

233 atter (corpus callosum, corticospinal tract, fornix system) increase; in TASTPMs such trends often va

234 Higher microstructural integrity in the fornix tail was found to be associated with significantl

235 cortex, corpus callosum, habenulae, septum, fornix, thalamus, caudate putamen and a few in fasciculu

236 The men had a lower fiber density in the fornix than the women.

237 o-anterior temporal lobe, including PrC) and fornix (the main HC input/output pathway) correlated wit

238 g a 5-mul fluorescein drop into the inferior fornix, the inferior tear meniscus was depleted using a

239 nesia depends on determining the role of the fornix, the major interlinking fiber tract.

240 Transecting the fornix, the major route from hippocampus to subcortical

241 n to link components of memory networks: the fornix, the parahippocampal cingulum, and the uncinate f

242 emonstrated that DBS targeted to the fimbria-fornix, the region that appears to regulate hippocampal

243 into corpus callosum, striatum, and fimbria fornix to differentiate into the NG2-positive nonmyelina

244 keys received a bilateral transection of the fornix to disconnect subcortical inputs and outputs of t

245 The hippocampus is connected via the fornix tract to the hypothalamus, orbitofrontal cortex,

246 icine-pretreated, control, untreated fimbria-fornix-transected (5 days), as well as perforant path-st

247 ased on the delayed matching-to-sample task, fornix-transected and normal control monkeys were presen

248 Fornix-transected monkeys were impaired in learning new

249 ere impaired nonsignificantly, and less than fornix-transected rats in an earlier study.

250 Both fornix transection and selective neurotoxic hippocampal

251 Taken together, these results show that fornix transection causes a long-lasting impairment in a

252 In contrast to these effects, fornix transection did not impair performance when famil

253 iscrimination learning task, they found that fornix transection did not impair recall of preoperative

254 Fornix transection impaired the learning of these associ

255 Here the authors demonstrate that fornix transection impairs learning about spatial stimul

256 eports of spatial learning impairments after fornix transection in nonhuman primates, critically high

257 acquired preoperatively was unaffected after fornix transection in the macaque, whereas new postopera

258 ive reassigned stages, however, monkeys with fornix transection made on average three times as many e

259 This suggests that fornix transection should impair postoperative new learn

260 In experiment 4, fornix transection significantly impaired tests of WSR a

261 d subjacent parahippocampal cortex, added to fornix transection, had no effect, thus demonstrating th

262 After the well-trained monkeys received fornix transection, they were impaired in learning new v

263 ed by lesions of the mammillary bodies, like fornix transection, was exacerbated by prior removal of

264 within the extended hippocampal system, via fornix transection.

265 Fimbria-fornix transections (FFTs), conducted 1 day after rats w

266 tion, had no effect, thus demonstrating that fornix transections eliminated the contribution of the h

267 molgous) monkeys received unilateral fimbria fornix transections followed by chronic intracranial can

268 In previous work, the authors found that fornix transections impaired the ability of macaque monk

269 describing larger GFAP RNA inductions after fornix transections in aged mouse hippocampus.

270 The 'upper fornix trap', where the contact lens may be retained by

271 ion of anterior temporal stem, amygdala, and fornix (TS+AM+FX) and were unimpaired in performing the

272 0.03% eye ointment instilled into the lower fornix twice daily for the first 2 weeks, followed by no

273 orm cortex, and a white-matter index for the fornix, uncinate fasciculus and inferior longitudinal fa

274 ructural brain connectivity of the amygdala, fornix, uncinate fasciculus, and cingulum was assessed u

275 n isolated from the nictitating membrane and fornix using explant cultures.

276 ecline but was significantly associated with fornix volume and diffusivity (P = .004).

277 Predictive fornix volume reductions might be explained at least in

278 In this study relating fornix volume with memory, we made magnetic resonance im

279 A (0.38 vs. 0.46, means adjusted for age and fornix volume, P<.0005) and mammillary body volumes (age

280 RCTs in which benefits and complications of fornix- vs limbal-based trabeculectomy for glaucoma were

281 n demonstrated that FA of the columns of the fornix was a better predictor of mutation status than wa

282 Burst stimulation of the fornix was not perceived by any of the participants but

283 A section of fornix was removed from each hemisphere of postmortem br

284 ted decline in white matter integrity of the fornix, was associated with lower cross-sectional episod

285 luding the posterior cingulum bundle and the fornix were also found.

286 Pathological changes in the dorsal fornix were beyond the margins of resection, and contral

287 In both species, changes in diffusion in the fornix were correlated with diffusion changes in the hip

288 on nerve fibers and neuroglial cells in the fornix were examined in 25 rhesus monkeys between 4 and

289 ampal cingulum bundle, stria terminalis, and fornix were investigated as regions of interest.

290 isions of the corpus callosum, cingulum, and fornix were measured as indicators of trait differences

291 and rats with radio-frequency lesions of the fornix were tested on the visual paired comparison task

292 of the anterior temporal stem, amygdala and fornix were unable to relearn a 2-choice object discrimi

293 with decreased fractional anisotropy in the fornix when compared with clinical (p < .001) or healthy

294 groups consistently had decreased FA in the fornix, which correlated with cognitive performance (rho

295 he presence of bilateral interruption of the fornix, which occurred in three of the subjects.

296 These results suggest that fornix white matter glia damage may cause hippocampal gr

297 nvestigate whether individual differences in fornix white matter microstructure in neurologically hea

298 Our preliminary hypothesis was that fornix white matter volume should be a significant predi

299 Thus, microstructural changes in fornix white matter were observed in older adults with i

300 buckle was inserted deeply into the inferior fornix without suture after pneumatic retinopexy and was