ライフサイエンスコーパス: fractional flow reserve

1 tial advantages of these new parameters over fractional flow reserve.

2 osis) who underwent invasive angiography and fractional flow reserve.

3 Lesion severity was assessed using fractional flow reserve.

4 ements of relative coronary flow reserve and fractional flow reserve.

5 sure ratio and diastolic pressure ratio) and fractional flow reserve.

6 l angiography-based approach to estimate the fractional flow reserve.

7 arization in coronary lesions with gray-zone fractional flow reserve.

8 underwent invasive coronary angiography with fractional flow reserve.

9 oronary artery lesions and validated against fractional flow reserve.

10 ructive CAD by invasive coronary angiography-fractional flow reserve.

11 mental value of hybrid imaging compared with fractional flow reserve.

12 ovides an estimate of local hemodynamics and fractional flow reserve.

13 t of PCI assessed by the measure of post PCI fractional flow reserve.

14 al (CI): 0.40 to 1.25, P = 0.0068] and lower fractional flow reserve (-0.07; 95% CI: -0.12 to -0.02,

15 (Vasodilator Free Measure of Fractional Flow Reserve [ADVISE]; NCT01118481).

16 e effects and time requirements of adenosine fractional flow reserve (aFFR) and improves diagnostic p

17 Fractional flow reserve, an invasive index of stenosis s

18 Key highlights include the role of CT fractional flow reserve analysis to guide patient manage

19 ronary angiography (ICA), including 3-vessel fractional flow reserve and coronary flow reserve measur

20 baseline and hyperemic conditions as well as fractional flow reserve and coronary flow velocity reser

21 0.77; 95% CI, 0.71-0.83) was as accurate as fractional flow reserve and coronary flow velocity reser

22 and IMR(true) became greater with decreasing fractional flow reserve and increasing coronary wedge pr

23 ong evidence of an association between lower fractional flow reserve and instantaneous wave-free rati

24 FIRST (Fractional Flow Reserve and Intravascular Ultrasound Rel

25 (Fractional Flow Reserve and Intravascular Ultrasound Rel

26 Consequently, fractional flow reserve and nonhyperemic pressure-derive

27 of all diagnostic tests, including invasive fractional flow reserve and noninvasive coronary flow re

28 r PCI in stenoses defined physiologically by fractional flow reserve and other parameters.

29 RbPET and invasive coronary angiography with fractional flow reserve and quantitative coronary angiog

30 an invasive coronary angiography (ICA) with fractional flow reserve and thermodilution-based coronar

31 The index of microvascular resistance (IMR), fractional flow reserve, and coronary flow reserve were

32 llowed by coronary intravascular ultrasound, fractional flow reserve, and index of microcirculatory r

33 ronary angiography, stress echocardiography, fractional flow reserve, and instantaneous wave-free rat

34 sting and hyperemic systolic gradient [HSG], fractional flow reserve, and mean gradient) were measure

35 epicardial severity quantification based on fractional flow reserve, and nonendothelial microvascula

36 non-hyperaemic coronary pressure ratios and fractional flow reserve, and the potential advantages of

37 cations of PCI in the setting of an abnormal fractional flow reserve are unknown.

38 PI/LGE integration were determined having XA+fractional flow reserve as standard for coronary artery

39 operating characteristic curve (AUC), using fractional flow reserve as the gold standard (values < 8

40 rve) study and the DeFACTO (Determination of Fractional Flow Reserve by Anatomic Computed Tomographic

41 FFR pullback and the noninvasive equivalent, fractional flow reserve by computed tomography (FFR(CT))

42 scintigraphy studies also increased, as did fractional flow reserve by CT since its introduction.

43 Keywords: Angiography, CT, CT-Angiography, Fractional Flow Reserve, Cardiac, Heart, Arteriosclerosi

44 Contrast fractional flow reserve (cFFR) is a method for assessing

45 rast media for rapid measurement of contrast fractional flow reserve (cFFR) obviates the side effects

46 ar ultrasound, optical coherence tomography, fractional flow reserve, coronary flow reserve, and inde

47 Fractional flow reserve, coronary flow reserve, and the

48 coronary assessment, including angiography, fractional flow reserve, coronary flow reserve, the inde

49 ion, epicardial and microvascular spasm, low fractional flow reserve, coronary microvascular dysfunct

50 Pre-PCI fractional flow reserve correlated modestly with IMR(app

51 CT-derived fractional flow reserve (CT-FFR) analyses assessed the h

52 es a retrospective observational study of CT fractional flow reserve (CT-FFR) analysis using dual-sou

53 Background CT-derived fractional flow reserve (CT-FFR) and dynamic CT myocardi

54 clinical feasibility of workstation-based CT fractional flow reserve (CT-FFR) for coronary artery dis

55 ackground The role of CT angiography-derived fractional flow reserve (CT-FFR) in pre-transcatheter ao

56 Computed tomography-derived fractional flow reserve (CT-FFR) is a clinically used mo

57 Fractional flow reserve derived from CT is a rapidly dev

58 onary computed tomography angiography (CTA), fractional flow reserve derived with coronary CTA (FFR(C

59 Secondary study end points were fractional flow reserve during vessel patency, the quant

60 Fractional flow reserve estimated using computed tomogra

61 -ray invasive coronary angiography (XA) with fractional flow reserve evaluation.

62 e report a technique for performing invasive fractional flow reserve (FFR(INV)) by minimizing pressur

63 Invasive fractional flow reserve (FFR(INV)) is the standard techn

64 -infarct-related coronary arteries guided by fractional flow reserve (FFR) (295 patients) or to under

65 Fractional flow reserve (FFR) after percutaneous coronar

66 ndothelial function testing; measurements of fractional flow reserve (FFR) and coronary flow reserve

67 Discordance between fractional flow reserve (FFR) and coronary flow velocity

68 e coronary flow reserve (CFR) divided by the fractional flow reserve (FFR) and corrected for driving

69 Fractional flow reserve (FFR) and instantaneous wave-fre

70 cular ultrasound (IVUS) that correlates with fractional flow reserve (FFR) and to assess the correlat

71 esonance (CMR) against invasively determined fractional flow reserve (FFR) and to establish the corre

72 CMR to detect functionally relevant CAD with fractional flow reserve (FFR) as a reference standard in

73 sing invasive coronary angiography (ICA) and fractional flow reserve (FFR) as reference standards.

74 ctionally significant coronary lesions using fractional flow reserve (FFR) as the reference standard.

75 lue of coronary CT angiography (CTA)-derived fractional flow reserve (FFR) beyond 1-year outcomes and

76 nts with intermediate stenosis with abnormal fractional flow reserve (FFR) but preserved coronary flo

77 ronary angiography (ICA) with measurement of fractional flow reserve (FFR) by means of a pressure wir

78 percutaneous coronary intervention guided by fractional flow reserve (FFR) compared with percutaneous

79 esent study sought to determine the value of fractional flow reserve (FFR) compared with stress perfu

80 Fractional flow reserve (FFR) computation from coronary

81 Measurement of fractional flow reserve (FFR) constitutes the current go

82 quals coronary flow reserve (CFR) divided by fractional flow reserve (FFR) corrected for driving pres

83 Positive fractional flow reserve (FFR) documents functional signi

84 ompression of the anomalous vessel, invasive fractional flow reserve (FFR) during a dobutamine-atropi

85 nary flow reserve (CFR) and pressure derived fractional flow reserve (FFR) for coronary stenosis asse

86 Measurement of fractional flow reserve (FFR) has an established role in

87 Detection of coronary ischemic lesions by fractional flow reserve (FFR) has been established as th

88 Determination of fractional flow reserve (FFR) has been proposed as a mea

89 ies in which PCI is guided by measurement of fractional flow reserve (FFR) have been lacking.

90 Although pressure-only fractional flow reserve (FFR) improves outcomes compared

91 The use of fractional flow reserve (FFR) in acute coronary syndrome

92 llowed by invasive coronary angiography with fractional flow reserve (FFR) in all coronary arteries.

93 Penetration of fractional flow reserve (FFR) in clinical practice varie

94 The value of fractional flow reserve (FFR) in determining the appropr

95 everity of a coronary stenosis comparable to fractional flow reserve (FFR) in diagnostic categorizati

96 ssure (Pd) to mean aortic pressure (Pa), and fractional flow reserve (FFR) in patients undergoing pri

97 d to examine the correlation between PTC and fractional flow reserve (FFR) in patients with coronary

98 the main vessel (MV) stent expansion and SB fractional flow reserve (FFR) in patients with coronary

99 s of angiographic diameter stenosis (DS) and fractional flow reserve (FFR) in predicting natural hist

100 The index has been tested against fractional flow reserve (FFR) in small trials, and the t

101 ce of these ischemic heart disease levels in fractional flow reserve (FFR) interrogated vessels remai

102 In contrast, fractional flow reserve (FFR) is a physiologic measure o

103 Fractional flow reserve (FFR) is a reliable tool for the

104 assessment of coronary artery disease using fractional flow reserve (FFR) is a well-validated techni

105 Fractional flow reserve (FFR) is an invasive measurement

106 Fractional flow reserve (FFR) is an invasive procedure u

107 onary intervention in nonischemic lesions by fractional flow reserve (FFR) is associated with excelle

108 Fractional flow reserve (FFR) is commonly used to assess

109 Fractional flow reserve (FFR) is considered by many inve

110 Fractional flow reserve (FFR) is considered nowadays as

111 ry artery bypass grafting (CABG), the use of fractional flow reserve (FFR) is insufficiently investig

112 However, validation of BOLD CMR against fractional flow reserve (FFR) is lacking.

113 Fractional flow reserve (FFR) is not firmly established

114 Invasive fractional flow reserve (FFR) is now the gold standard f

115 complete revascularization that is guided by fractional flow reserve (FFR) is superior to an angiogra

116 ntion (PCI) for nonculprit lesions guided by fractional flow reserve (FFR) is superior to treatment o

117 Fractional flow reserve (FFR) is the current gold standa

118 Fractional flow reserve (FFR) is the gold standard metri

119 ographic assessment of coronary stenoses and fractional flow reserve (FFR) is weak.

120 Fractional flow reserve (FFR) is well established for pa

121 US), coronary flow velocity reserve (CVR) or fractional flow reserve (FFR) may further enhance the ab

122 The predictive value of fractional flow reserve (FFR) measured immediately after

123 Several studies have shown that fractional flow reserve (FFR) measurement can aid in the

124 The use and clinical outcomes of fractional flow reserve (FFR) measurement in patients wi

125 Fractional flow reserve (FFR) measurement of intermediat

126 During fractional flow reserve (FFR) measurement, the simple pr

127 , and a pressure wire was used for reference fractional flow reserve (FFR) measurement.

128 nts with intermediate stenoses (53+/-7%), 14 fractional flow reserve (FFR) measurements (using 0.014-

129 ues of IVUS parameters at which to predict a fractional flow reserve (FFR) of 0.75 are unknown.

130 We hypothesized that fractional flow reserve (FFR) of an infarct-related arte

131 arge collateral contribution might alter the fractional flow reserve (FFR) of an interrogated vessel,

132 Aortic valve stenosis may influence fractional flow reserve (FFR) of concomitant coronary ar

133 There is no large report of the impact of fractional flow reserve (FFR) on the reclassification of

134 ase (CAD), guidelines recommend using either fractional flow reserve (FFR) or instantaneous wave-free

135 ation decisions based on angiography-derived fractional flow reserve (FFR) or optimisation of stent i

136 Intracoronary pressure wire measurement of fractional flow reserve (FFR) provides decision-making g

137 ery disease patterns can be quantified using fractional flow reserve (FFR) pullbacks incorporating th

138 he severity of the stenosis as determined by fractional flow reserve (FFR) remains unknown.

139 Assessment of stenosis severity with fractional flow reserve (FFR) requires that coronary res

140 Fractional flow reserve (FFR) specifically relates to th

141 The utility of measuring fractional flow reserve (FFR) to assess cardiac transpla

142 Measurement of fractional flow reserve (FFR) to guide coronary revascul

143 A fractional flow reserve (FFR) value 0.90 after percutane

144 The fractional flow reserve (FFR) value of 0.75 has been val

145 Pre-PCI fractional flow reserve (FFR) was lower among patients w

146 agnostic performance with respect to iFR and fractional flow reserve (FFR) were calculated for all in

147 Measuring fractional flow reserve (FFR) with a pressure wire remai

148 This study sought to compare fractional flow reserve (FFR) with the instantaneous wav

149 rvention (PCI) performed on the basis of the fractional flow reserve (FFR) would be superior to medic

150 stenoses: (1) pressure wire-derived coronary fractional flow reserve (FFR), (2) Doppler wire-derived

151 Fractional flow reserve (FFR), an index of the hemodynam

152 ascular resistance reserve (MRR) adjusts for fractional flow reserve (FFR), and thus is theoretically

153 Paired fractional flow reserve (FFR), coronary flow reserve (CF

154 the instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR), from early experimental s

155 lculate instantaneous wave-free ratio (iFR), fractional flow reserve (FFR), hyperemic stenosis resist

156 erived CFR and IMR were measured, along with fractional flow reserve (FFR), in 15 coronary arteries (

157 ted against the invasive reference standard, fractional flow reserve (FFR), in patients with suspecte

158 This has not previously been assessed for fractional flow reserve (FFR), instantaneous wave-free r

159 nt stenoses, as determined by measurement of fractional flow reserve (FFR), percutaneous coronary int

160 ysis of 3 prospective observational studies, fractional flow reserve (FFR), resting full-cycle ratio

161 ntracoronary physiology assessment measuring fractional flow reserve (FFR), the index of microcircula

162 ques have been used to noninvasively compute fractional flow reserve (FFR), which is the ratio of max

163 s of quantitative [(15)O]H(2)O PET to detect fractional flow reserve (FFR)-defined coronary artery di

164 Even after fractional flow reserve (FFR)-guided complete revascular

165 Despite fractional flow reserve (FFR)-guided deferral of revascu

166 ivessel coronary artery disease treated with fractional flow reserve (FFR)-guided PCI compared with C

167 study was to assess the clinical outcome of fractional flow reserve (FFR)-guided PCI in the treatmen

168 Fractional flow reserve (FFR)-guided PCI is associated w

169 phy for Multivessel Evaluation (FAME) study, fractional flow reserve (FFR)-guided percutaneous corona

170 Outcomes in patients with diabetes after fractional flow reserve (FFR)-guided percutaneous corona

171 evation Myocardial Infarction) showed that a fractional flow reserve (FFR)-guided strategy was not su

172 s study was aimed at investigating whether a fractional flow reserve (FFR)-guided SYNTAX score (SS),

173 on imaging allows to noninvasively calculate fractional flow reserve (FFR).

174 group of 26 vessels) invasive measurement of fractional flow reserve (FFR).

175 CT-IP]) assessment in predicting significant fractional flow reserve (FFR).

176 ng functional stenosis severity evaluated by fractional flow reserve (FFR).

177 e to intravenous adenosine on calculation of fractional flow reserve (FFR).

178 s wave-free ratio (iFR) approximation to the fractional flow reserve (FFR).

179 ly severe coronary stenoses as determined by fractional flow reserve (FFR).

180 lves invasive angiography and measurement of fractional flow reserve (FFR).

181 gnostic accuracy to Pd/Pa when compared with fractional flow reserve (FFR).We hypothesized that in co

182 Computed tomography-derived fractional flow reserve (FFR-CT) is a novel, noninvasive

183 all others to cCTA with selective CT-derived fractional flow reserve (FFR-CT).

184 uminal stenosis, computed tomography-derived fractional-flow reserve (FFR(CT)), and high-risk plaque

185 n and at least 1 other severely obstructive (fractional flow reserve [FFR] </=0.8) nontarget lesion (

186 ssure with hyperemia-induced vasodilatation (fractional flow reserve [FFR] </=0.80).

187 (FAME II - Fractional Flow Reserve [FFR] Guided Percutaneous Corona

188 Fractional flow reserve (FFRCT) using computed tomograph

189 erve, index of microvascular resistance, and fractional flow reserve, followed by coronary vasoreacti

190 ing is a noninvasive alternative to invasive fractional flow reserve for evaluating hemodynamically s

191 ared with invasive coronary angiography with fractional flow reserve for the diagnosis of hemodynamic

192 y with selective computed tomography-derived fractional flow reserve for the remainder.

193 diac MRI and coronary CT angiography-derived fractional flow reserve from real-world trials has incre

194 vailable technologies and techniques include fractional flow reserve; grayscale intravascular ultraso

195 ms), no angiographically severe stenosis and fractional flow reserve > 0.80 undergoing coronary funct

196 ned unnecessary coronary angiography (normal fractional flow reserve >0.8 or quantitative coronary an

197 0 gained Delta28.5+/-3.8 cm/s, whereas those fractional flow reserve >0.80 had a significantly smalle

198 patients with diabetes and >=1 lesion with a fractional flow reserve >0.80 underwent OCT evaluation a

199 nsidered obstructive; a stenosis <30% and/or fractional flow reserve >0.80 was nonobstructive.

200 ed 18 years or older with non-flow-limiting (fractional flow reserve >0.80) vulnerable coronary plaqu

201 noninfarct-related stenosis on the effect of fractional flow reserve-guided complete revascularizatio

202 The benefit from fractional flow reserve-guided complete revascularizatio

203 In patients with 3-vessel disease, fractional flow reserve-guided complete revascularizatio

204 -elevation myocardial infarction patients to fractional flow reserve-guided complete revascularizatio

205 patients with 3-vessel CAD to either CABG or fractional flow reserve-guided PCI using zotarolimus dru

206 Fractional flow reserve-guided PCI using zotarolimus dru

207 raphy for Multivessel Evaluation 3) compared fractional flow reserve-guided PCI with CABG in patients

208 In the FAME 3 trial, quality of life after fractional flow reserve-guided PCI with current generati

209 The fractional flow reserve has dominated this evolving phys

210 PCI of lesions with reduced fractional flow reserve improves long-term outcome and i

211 PCI of coronary lesions with reduced fractional flow reserve improves outcomes and appears ec

212 In the DISENGAGE (Determination of Fractional Flow Reserve in Intermediate Coronary Stenosi

213 The use of fractional flow reserve in patients with non-ST-segment-

214 The clinical use of fractional flow reserve in the culprit vessel may be pre

215 In those with isolated LMCA disease, fractional flow reserve in the LAD was lower than in the

216 Fractional flow reserve in these 3 groups was 0.86+/-0.0

217 of revascularization (for example, guided by fractional flow reserve) in those patients with persiste

218 RCA fractional flow reserve increased significantly (P=0.002

219 Intravascular ultrasound (IVUS) and fractional flow reserve index (FFR) provide anatomic and

220 Fractional flow reserve, instantaneous wave-free ratio,

221 an provide valuable functional insights with fractional flow reserve integration.

222 Pressure wire-based fractional flow reserve is considered the standard of re

223 Fractional flow reserve less than 0.8, as measured durin

224 nary flow reserve < 2.0 and pressure-derived fractional flow reserve < 0.75, both variables related s

225 artery disease (>/=90% stenosis/occlusion or fractional flow reserve </= 0.80 in vessels>2 mm).

226 Fractional flow reserve </= 0.80 was considered diagnost

227 A >/=50% stenosis at ICA or a fractional flow reserve </= 0.80 was considered signific

228 ts with significant coronary artery disease (fractional flow reserve </=0.75) to high-intensity exerc

229 failure included IMR >40 (HR, 2.2; P=0.026), fractional flow reserve </=0.8 (HR, 3.24; P=0.008), and

230 coronary vessel, or 30% to 70% stenosis with fractional flow reserve </=0.8.

231 iological cut points; treating stenoses with fractional flow reserve </=0.80 gained Delta28.5+/-3.8 c

232 Invasive fractional flow reserve </=0.80 or diameter stenosis >/=

233 A stenosis >90% and/or fractional flow reserve </=0.80 was considered obstructi

234 angina and at least 1 coronary lesion with a fractional flow reserve </=0.80 who were randomized to p

235 [9] years), 92 (44.2%) had significant CAD (fractional flow reserve </=0.80).

236 invasive coronary angiography stenosis >90%, fractional flow reserve <0.80, or a quantitative coronar

237 A fractional flow reserve <0.96, measured after stent depl

238 function was present in 60% of the patients; fractional flow reserve <=0.8, coronary flow reserve <2,

239 reserve of 0.84 (0.82-0.87), and 19.6% had a fractional flow reserve <=0.8.

240 hy) or hemodynamically obstructive (ICA with fractional flow reserve <=0.80).

241 er stenosis or invasive coronary angiography-fractional flow reserve <=0.80, and sensitivity analyses

242 modynamically obstructive CAD defined as ICA fractional flow reserve <=0.80, was identified in 86/196

243 ntitative coronary analysis stenosis >50% if fractional flow reserve measurements were not feasible.

244 ography, as well as coronary angiography and fractional flow reserve measurements where available.

245 ar ultrasound, optical coherence tomography, fractional flow reserve measurements, bare-metal stents,

246 ive coronary angiography in conjunction with fractional flow reserve measurements.

247 angiography (CCTA) derived machine learning fractional flow reserve (ML-FFR(CT)) can assess the hemo

248 lesion stenosis was 80 (70-90)% and pre-PCI fractional flow reserve (n=7) was 0.72 (0.67-0.74).

249 Among diabetes patients with fractional flow reserve-negative lesions, patients carry

250 Invasive tools, such as fractional flow reserve, nonhyperemic pressure ratios, i

251 In 8 stenosed animals with a mean fractional flow reserve of 0.64+/-0.02, hyperoxia result

252 s had mean area stenosis of 84.4% (SD 10.2), fractional flow reserve of 0.69 (0.16), and instantaneou

253 at least 1 coronary artery as indicated by a fractional flow reserve of 0.80 or less and relative dia

254 at least one coronary-artery stenosis with a fractional flow reserve of 0.80 or less or a diameter st

255 CFT revealed a median fractional flow reserve of 0.84 (0.82-0.87), and 19.6% h

256 tolic pressure ratio of 0.94+/-0.06, and the fractional flow reserve of 0.90+/-0.07.

257 Fractional flow reserve of the IRA accurately identifies

258 onary flow reserve, and the pressure-derived fractional flow reserve of the myocardium.

259 athy, in a manner analogous to the effect of fractional flow reserve on the management of stable angi

260 utcome in patients from FAME 1 and 2 trials (Fractional Flow Reserve or Angiography for Multivessel E

261 puted tomography or computed tomographic and fractional flow reserve or FFR.

262 d non-invasive techniques are available (eg, fractional flow reserve or intravascular ultrasound) or

263 y with selective computed tomography-derived fractional flow reserve, or to usual testing (stress tes

264 s, ICP-intracranial pressure; FFR = Pd/Pa is fractional flow reserve (Pd scaled to the systemic press

265 CT myocardial perfusion imaging and CT fractional flow reserve provide added diagnostic accurac

266 ow velocity reserve and the more widely used fractional flow reserve relies critically on the establi

267 In lesions with gray-zone fractional flow reserve, revascularization was associate

268 on with severity of ischemia, as assessed by fractional flow reserve (Somers' D 0.124, Pr=0.057) or i

269 eement: -0.09 to 0.03), proportional to mean fractional flow reserve (Spearman rho =0.40; P=0.036).

270 The FFR-SEARCH (Fractional Flow Reserve-Stent Evaluated at Rotterdam Car

271 ia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) study and the DeFACTO (Determin

272 sk level as assessed by noninvasive testing, fractional flow reserve testing, and coronary anatomy.

273 PCI is associated with higher postprocedure fractional flow reserve than PCI guided by angiography a

274 higher for PCI in the setting of an abnormal fractional flow reserve than with medical therapy ($9927

275 ied patients) may require a pressure-derived fractional flow reserve to differentiate persistent obst

276 graphic angiography (CTA) plus estimation of fractional flow reserve using CTA (FFRCT) safely and eff

277 CT-guided group, with a significantly higher fractional flow reserve value (0.94+/-0.04 versus 0.92+/

278 Management of coronary lesions with fractional flow reserve values in the gray zone (0.75-0.

279 arization of coronary lesions with gray-zone fractional flow reserve values.

280 In the Fractional Flow Reserve Versus Angiography for Multivess

281 The Fractional Flow Reserve Versus Angiography for Multivess

282 lected in 497 patients enrolled in the FAME (Fractional Flow Reserve versus Angiography for Multivess

283 The Fractional Flow Reserve Versus Angiography for Multivess

284 FAME 3 (Fractional Flow Reserve versus Angiography for Multivess

285 The FAME 3 trial (Fractional Flow Reserve Versus Angiography for Multivess

286 FAME 2 trial (Fractional Flow Reserve Versus Angiography for Multivess

287 The British Heart Foundation Fractional Flow Reserve Versus Angiography in Guiding Ma

288 uded the 607 patients from the FAME 2 trial (Fractional Flow Reserve Versus Angiography in Multivesse

289 prespecified subgroup analysis of the FAME (Fractional Flow Reserve vs Angiography for Multivessel E

290 In the target vessels, the median fractional flow reserve was 0.63 (interquartile range, 0

291 cardiography score was 1.0 (Q1-Q3: 0.0-2.7), fractional flow reserve was 0.63 (Q1-Q3: 0.49-0.75), and

292 Mean fractional flow reserve was 0.68+/-0.02.

293 Mean fractional flow reserve was 0.86+/-0.06 for wire-only as

294 Median fractional flow reserve was 0.88 (interquartile range, 0

295 Conclusion CT angiography-derived fractional flow reserve was associated with major advers

296 with examination of all coronary arteries by fractional flow reserve was performed from January 23, 2

297 Fractional flow reserve was performed in patients with m

298 4/18 (77.8%) and was abnormal in 7/14 (50%); fractional flow reserve was positive in 5/8 (62.5%).

299 Invasive coronary angiography with invasive fractional flow reserve was the reference standard.

300 ivessel coronary artery disease with reduced fractional flow reserve were randomly assigned to PCI pl

301 ltivessel Evaluation) compared PCI guided by fractional flow reserve with best MT in patients with st