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1 iamonds, based upon data from an exceptional fragment of a diamond-bearing peridotite, its clinopyrox
3 h selectivity, ii) tightly bind a structured fragment of a housekeeping gene mRNA, and iii) cleave it
5 ies are known from Antarctica, a new dentary fragment of a pelagornithid bird from the middle Eocene
10 ger Dryas (YD) impact hypothesis posits that fragments of a large, disintegrating asteroid/comet stru
12 oid must be a rubble pile formed from impact fragments of a parent body with microporosity(9) of appr
18 rminal portion, the C-terminal tyrosine-rich fragment of ALIX-PRD forms amyloid fibrils and viscous g
21 ory marker) and low sAPPbeta (a soluble beta fragment of amyloid precursor protein) in cerebrospinal
22 ucture to 1.8 angstrom resolution of the Fab fragment of an affinity-matured human monoclonal antibod
23 ans of antigen recognition, in which the Fab fragment of an antibody acts as an adaptor, linking a hu
25 ous rubble-pile object generated from impact fragments of an undifferentiated aqueously altered paren
26 route affording more than a gram of a major fragment of anti-HIV agents rubriflordilactones A and B
28 w method for covalent immobilization of half-fragments of antibodies on silicon modified by 3-glycido
31 nti-HT2 immune complex single-chain variable fragment of antibody fused with alkaline phosphatase (an
32 sing a structurally homologue apolipoprotein fragment of apoA-I (4F) complexed with Abeta(M1-42) and
35 script, we propose that the 99-aa C-terminal fragment of APP (C99), when delivered to the ER for clea
36 hypothesis proposes that a small amphipathic fragment of APP, the amyloid beta-protein (Abeta), self-
37 the levels of the membrane-bound C-terminal fragments of APP from both alpha-secretase cleavage (alp
42 cal extracts was around 20-220bp compared to fragments of around 600bp for the more easily visualized
50 re, we compare C5a and a modified C-terminal fragment of C5a, C5a(pep), in terms of G-protein couplin
52 cy of CD11b or Ly-6C/Ly-6G-specific variable fragments of camelid heavy chain-only antibodies (VHH) c
53 of the chemical syntheses of oligosaccharide fragments of cellulose, hemicellulose, pectin, and arabi
54 lts in dimers, trimers, tetramers, or longer fragments of chains of face-sharing octahedra in the cry
55 arify these relationships by studying larger fragments of cheetah mtDNA, both from an Indian cheetah
56 respond to OS via recognition of proteolytic fragments of chloroplastic ATP synthase, termed inceptin
59 loped a technically robust assay targeting a fragment of COL6, which was elevated in serum from patie
60 n to have biological activities, including a fragment of complement C3, the spasmogenic C3f, which wa
62 th and without bound ligand of a recombinant fragment of conglutinin's C-terminal carbohydrate-recogn
63 agExtract), tandem mass spectrometry (MS/MS) fragments of corresponding native and uniformly labeled
64 Diamonds and their inclusions are unique fragments of deep Earth, which provide rare samples from
65 (SCC) EVs were enriched with the C-terminal fragment of desmoglein 2 (Dsg2), a desmosomal cadherin o
66 ion, we generated a panel of oligosaccharide fragments of different lengths and tested them with poly
68 the other hand, the highly homologous Klenow fragment of DNA polymerase I containing an engineered gp
69 t reasonably good efficiency with the Klenow fragment of DNA polymerase I, and we identify thermostab
70 these clones revealed that they all share a fragment of DNA with homology to the genome of Bacteroid
71 g short DNA reads sourced from the same long fragment of DNA; subsequently, the tagged reads are sequ
73 characterization and visualization of small fragments of DNA in processed botanical materials and wi
76 g signals of dentin sialoprotein (N-terminal fragment of DSPP) were decreased in the dentin matrix, t
77 lution of 2.5 A of a complex between the Fab fragments of E1 and HM14c10 and provide the first detail
78 lution of 2.5 A of a complex between the Fab fragments of E1 and HM14c10 provides the first detailed
79 l degranulation, and IgG1 or antigen-binding fragments of each anti-SEE enhanced degranulation by the
82 mined the solution structure of a C-terminal fragment of eEF-2K, eEF-2K(562-725) that encodes two alp
88 The obtained glycoconjugates are related to fragments of exopolysaccharide galactosaminogalactan (GG
89 iscs) of the NGLs and their affinities for a fragment of family 51 carbohydrate-binding module (CBM)
90 ion and early fiber breakage, and that small fragments of fibers can play an important role in the pr
91 dynamic process in which participants replay fragments of fine-grained temporal patterns and are able
93 trate that acutely introducing an N-terminal fragment of FMRP into BCs normalizes GABA release in the
96 c elements, prokaryotes must first integrate fragments of foreign DNA into their genomic CRISPR array
97 course of CRISPR interference Cas3 generates fragments of foreign DNA that are recognized by the Cas1
98 rated from much longer S1-nuclease sensitive fragments of foreign DNA that require Cas3 for their pro
99 er adaptation, the Cas1-Cas2 complex selects fragments of foreign DNA, called prespacers, and integra
100 y alter their genomes by incorporating small fragments of foreign DNA, called spacers, into CRISPR lo
103 e are able to quantitatively detect a 563 bp fragment of genomic DNA of Mycobacterium avium subspecie
105 irely precluded production of the N-terminal fragment of HDAC4 but also promoted Ca(2+)/calmodulin-de
106 the cardio-protective N-terminal proteolytic fragment of HDAC4 is enhanced in vivo in patients with d
108 ential step for production of the N-terminal fragment of HDAC4, which was attenuated by Ca(2+)/calmod
109 used with the initially insoluble N-terminal fragment of hepatitis C virus' E2 protein were tested.
110 table mutant of hGal1 (hGal-1), a C-terminal fragment of hGal-3 (hGal-3C) and hGal-7), with known HMO
111 table mutant of hGal1 (hGal-1), a C-terminal fragment of hGal-3 (hGal-3C), hGal-7, and an N-terminal
112 hGal-3 (hGal-3C), hGal-7, and an N-terminal fragment of hGal-9 (hGal-9N), were measured using electr
114 udy, we sought to identify a minimal soluble fragment of HuCR1, which retains the complement regulato
115 e we report the X-ray crystal structure of a fragment of human ADAR2 comprising its deaminase domain
116 own interactions between a C-terminal domain fragment of human galectin-3 (hGal-3C) and three human s
118 y-relevant NHP brain circuits by packaging a fragment of human mutant HTT, the causative gene mutatio
121 adaptation, the Cas1-Cas2 complex integrates fragments of invader DNA as spacers in the CRISPR array.
122 Despite two crystal structures reported on fragments of IRBP and decades of research, the overall s
123 both undecorated and labelled with a soluble fragment of its cellular receptor, feline junctional adh
124 ATCC 27405, with both SAM and an N-terminal fragment of its peptidyl-substrate at 2.04 A resolution.
126 plex with rhesus CD4 and the antigen-binding fragment of ITS90.03 at 2.5- angstrom resolution reveale
129 interaction study of the C-dots and the DNA fragment of lambda bacteriophage was performed, and the
131 a histolytica kills human cells by ingesting fragments of live cells until the cell eventually dies,
135 of the nAChR alpha1 subunit bound by the Fab fragment of mAb35, a reference monoclonal antibody that
137 ave implicated calpain-dependent proteolytic fragments of menin, the product of the MEN1 tumor suppre
138 ircumsporozoite protein (CSP) and the 42-kDa fragment of merozoite surface protein 1 (MSP-1(42)) of P
139 trated in the synthesis of a tetrasaccharide fragment of Micrococcus luteus teichuronic acid containi
140 s such as microbes, metabolites, toxins, and fragments of microorganisms are present ubiquitously in
144 stal structures of an anaerobically prepared fragment of mouse viperin (residues 45-362) complexed wi
145 of the human genes, including small RNAs and fragments of mRNAs and long noncoding RNAs (lncRNAs).
146 port an experiment in which separating short fragments of musical discourse by vertical white gaps in
147 the accumulation of an amyloidogenic exon-1 fragment of mutant huntingtin (mHTTx1) modulates the exp
149 and Neandertals has resulted in introgressed fragments of Neandertal DNA in the genomes of present-da
151 evaluated deuterium uptake data from the Fab fragment of NISTmAb reference material (PDB: 5K8A ) from
152 w research suggests that a highly inhibitory fragment of Nogo-A is generated by the amyloid precursor
154 ostic criterion by which to identify ancient fragments of oceanic crust, and as a constraint on the f
155 he nuclear translocation of an intracellular fragment of ODZ1 through proteolytic cleavage by signal
156 nhibit activity in context of the DH/PH-DEP1 fragment of P-Rex1 and interacts with the DH/PH domains
158 mpared with the 140-kDa N-terminal catalytic fragment of p261 (p261N), which we kinetically character
159 1, Y1H screens were performed with a genomic fragment of P5CS1, containing 1.2-kB promoter and 0.8-kb
162 eptide GGP817 containing glucagon fused to a fragment of peptide YY (PYY) acted as a triagonist at th
165 e recent structure of a catalytically active fragment of PLCepsilon, provide the first evidence that
167 amyloidogenic peptides, namely, the 106-126 fragment of prion protein (PrP(106-126)) and the human i
170 smaller, soluble but relatively hydrophobic fragments of protein (plasmin-generated protein fragment
171 re believed to be solely derived from linear fragments of proteins, but this concept was challenged s
172 uggest that Hippocamp is probably an ancient fragment of Proteus, providing further support for the h
173 natural agonists of PTHR1, and an N-terminal fragment of PTH, PTH(1-34), is used clinically to treat
174 f otherwise poorly active N-terminal peptide fragments of PTH by conjugating them to nanobodies (VHHs
175 cations to concise preparation of the linear fragment of pumiliotoxin B (myotonic, cardiotonic) and e
179 on various preparative steps to generate DNA fragments of required concentration, purity and average
181 Robo and show that the cleaved extracellular fragment of Robo can function as a ligand for SYG-1/Neph
182 ow that neurons can release an extracellular fragment of Robo upon cleavage to attract glia during mi
183 etween genotypes introgressed by chromosomal fragments of Robusta and non-introgressed genotypes.
184 RPT1 interact in vitro, and the interacting fragment of RPT1 carries a PfPKG consensus phosphorylati
187 esent the crystal structure of an N-terminal fragment of Saccharomyces cerevisiae Hsp104 with the N d
188 we map the interaction of N- and C- terminal fragments of Sca2 and their contribution to actin bindin
189 ments covalently linked to one another or to fragments of secretory granule proteins or other islet-d
190 mediated decay (NMD) and xrn4 accumulates 3' fragments of select NMD targets, despite the lack of the
192 report the amplification of discrete target fragments of several kilobases at 37 degrees C from both
193 Our convergent approach couples two achiral fragments of similar complexity and employs an enantiose
197 of full-length STIM1 or a STING-interacting fragment of STIM1 suppressed the function of dominant ST
200 helial glycocalyx, releasing heparan sulfate fragments (of sufficient size and sulfation to bind BDNF
201 .67 megabytes of information stored in short fragments of synthetic DNA using a portable nanopore seq
203 be on the gold sensing chip and the unpaired fragment of target DNA works as a trigger to initiate th
204 ntify plasma concentrations of an N-terminal fragment of tau (NT1) in a large, well-characterized coh
206 smic inclusions of the prion-like C-terminal fragments of TDP-43 CTD (TDP-43 C-terminal domain), form
207 , the target protein, or a synthetic epitope fragment of that protein, provides a template for select
208 f the neuropeptide NAPVSIPQ (NAP), an active fragment of the activity-dependent neuroprotective prote
210 ffect, as well as leaving the rest targeting fragment of the affibody to specifically bind tumor over
213 We also synthesized the short N-terminal fragment of the atypically split CL intein by solid-phas
215 e, we investigate the binding processes of a fragment of the coronavirus spike protein receptor bindi
216 901 nucleotides containing a 210 bp inverted fragment of the DvSSJ1 gene, the formation of a double-s
218 testinal pathogen Vibrio cholerae A nontoxic fragment of the first 386 aa of cholix was genetically f
222 cised ~ 15 kilobases of DNA that contained a fragment of the integrated vector sequence and the neigh
224 o-EM reconstruction of an ~160-kD N-terminal fragment of the lipid transport protein VPS13 reveals an
225 -mer RNA probe specific for a characteristic fragment of the mitochondrial DNA D-loop region of horse
226 ylogenetic trees and time trees containing a fragment of the NS5B region of these and 374 circulating
228 Cambodia and after successful DNA extraction fragment of the nuclear rhodopsin gene (RH1) and 9 micro
229 The time-dependent change in the mass of any fragment of the polypeptide chain depends uniquely on th
230 atriuretic peptide [P < .001] and N-terminal fragment of the prohormone brain natriuretic peptide [P
234 efficients for RNA molecules (pseudoknots, a fragment of the rRNA, and the aptamer domain of the aden
235 pectrum probably overlaps with a derivatized fragment of the same metabolite, and D is modified propo
236 ineered adenoviruses containing a functional fragment of the shear-responsive endothelial nitric oxid
238 rids by sandwich hybridization of a specific fragment of the Sola l 7 allergen coding sequence with a
239 eyes, we sample only a small and incomplete fragment of the visual world, which needs to be contextu
240 nd our results suggest that mutations in the fragment of the vp2 gene were not required for infection
241 Cloning and sequencing of nearly full-length fragments of the 16S rRNA gene showed that some of the s
242 structure of a SUZ12-RBBP4 complex bound to fragments of the accessory subunits PHF19 and JARID2.
243 f insoluble, fibrillar aggregates of peptide fragments of the amyloid precursor protein (APP), typica
244 the degradation of intracellular C-terminal fragments of the amyloid precursor protein via the MVB/l
245 rom bacteriophages, but they instead package fragments of the entire bacterial genome without prefere
246 However, treatment of Y7A KI mice with Fab' fragments of the function-blocking anti-CLEC-2 antibody,
248 nd partitioning of large single-stranded DNA fragments of the homologous chromosome pairs allows for
249 embrane permeation and structural effects of fragments of the human IAPP and several rat IAPP mutants
250 olecules and precise cleavage and removal of fragments of the integrated proviral DNA from the genome
252 Nested 0.5- and 1.0-kilobase (kb) deletion fragments of the ITPR3 promoter were inhibited by NF-kap
253 affold-hopping, synthesis, and evaluation of fragments of the lead compounds and property-focused opt
254 shrew, Tupaia longipes, that inhabits forest fragments of the Lower Kinabatangan Wildlife Sanctuary,
255 parasite subpopulation, which have acquired fragments of the M. nemestrina associated subpopulation
257 ons by selection of the appropriate specific fragments of the mitochondrial DNA region and capture pr
258 Here, we show that those particles represent fragments of the plasma membrane that are pulled away an
259 cture of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal
260 undergoes proteolytic cleavage and processed fragments of the protein are released into the extracell
262 elopment and reintroduced variably truncated fragments of the pxr region to test for their ability to
265 flicting phylogenetic signals from different fragments of the SCMV genome, so it is not appropriate t
267 and structure elucidation of small molecule fragments of the stereochemically complex chlorosulfolip
269 ermined through both peptide and oxonium ion fragments, of the desialylated Abeta1-15 or Abeta1-17 gl
270 s are typically quantified using carboxylate fragments of their fatty acid moieties produced by highe
271 tures of the EV71 virion in complex with Fab fragments of these potent and protective antibodies reve
272 E) than controls, as well as the presence of fragments of these proteins not found in controls, sugge
274 uctures of the allergens in complex with Fab fragments of three murine mAbs that interfere with IgE A
275 RISPR editing identified a carboxyl-terminal fragment of thrombospondin-1 as an unexpected SMAP compo
282 in (IL)-6, IL-10, pentraxin (PTX) 3, soluble fragment of tumor necrosis factor-like weak inducer of a
285 ose to build an artificial double helix from fragments of two strands connected by covalent linkages
286 and pit formation and release of C-terminal fragment of type I collagen from cells cultured on bone
287 ype III collagen, the unhydroxylated quarter fragment of type III collagen, and synthetic peptides as
289 e candidate PAMVAC is based on a recombinant fragment of VAR2CSA, the Plasmodium falciparum protein r
291 I stoichiometry has been uncertain, and only fragments of VI have been identified in the virion struc
293 -bound A1 single domain and A1A2A3 tridomain fragment of VWF under shear stress in an ex vivo shear f
294 A1, A2, and A3 domains, an A1A2A3 tridomain fragment of VWF, plasmin-cleaved dimers of VWF, multimer
295 insic dynamics of A1 observed in recombinant fragments of VWF are conserved in plasma-derived VWF.
296 the common structural scaffold the chemical fragments of well-known antiepileptic drugs such as etho
297 esigned biotinylated probes to capture large fragments of Wolbachia DNA for sequencing using PacBio t
298 Thus, when expressed in mouse ESCs, a 5' fragment of Xist that contains Repeat-A sequesters RNA f
299 roughput sequencing of libraries composed of fragments of yeast genes to identify polypeptides that a