ライフサイエンスコーパス: fragmented

1 mitochondria are thick (swollen) and short (fragmented).

2 theory on rank orders in biology is somewhat fragmented.

3 underlying precise cell death control remain fragmented.

4 on and subpopulations are significantly more fragmented.

5 e understanding of these processes is rather fragmented.

6 Often, post-marketing research landscape is fragmented.

7 , and in many cases they become increasingly fragmented.

8 , and the present state of the literature is fragmented.

9 ver, our knowledge of this process is rather fragmented.

10 cent genome assemblies remain incomplete and fragmented.

11 identified, decorin was found to be the most fragmented.

12 eople with diabetes, especially when care is fragmented.

13 llary area (PICA) to determine if an FAZ was fragmented.

14 countries where food control systems may be fragmented.

15 -term precipitation trends in this region is fragmented.

16 sembled from short-read sequencing are often fragmented.

17 Here, we generated MVA-B13R by replacing the fragmented 181R/182R genes of MVA with a functional anti

18 cultured cells display both full-length and fragmented AAV genomes at Cas9 on-target sites.

19 enetic variants are commonly used but highly fragmented across many resources.

20 orpus of documentation of these resources is fragmented across the Web, with much redundancy, and has

21 ere investigated the capacity of human micro-fragmented adipose tissue (MFAT), used as a natural scaf

22 This is because ctDNA is a mix of fragmented alleles, and the contribution of different ca

23 preading drop, and the drop is then abruptly fragmented along with multiple nucleating holes.

24 amylopectin branches (especially those from fragmented amylopectin in EB).

25 However, since these bones are highly fragmented and anthropogenically modified, species deter

26 Genes often appear fragmented and are split into more genes during annotati

27 corridor was submerged, and populations were fragmented and consequently reduced to low Holocene leve

28 s of HD patients: impaired sleep initiation, fragmented and diminished sleep, and nighttime hyperacti

29 n populations living close to forest margins fragmented and disturbed by deforestation may be particu

30 s mediated, in great part, by the release of fragmented and dysfunctional microglial mitochondria int

31 s of its GTPase activity and in a buildup of fragmented and dysfunctional mitochondria in heart failu

32 Mitochondria exist in an equilibrium between fragmented and fused states that shifts heavily toward f

33 ria, national surveillance efforts are still fragmented and heterogeneous, and have substantial struc

34 However, these assemblies are mostly fragmented and inaccurate at the whole genome scale, lar

35 tivity, and show that it self-organizes from fragmented and incoherent states to connected and synchr

36 th species are available but they are highly fragmented and incomplete(1-4).

37 genomes, such as that of bread wheat, remain fragmented and incomplete.

38 nditions such as fatty liver disease remains fragmented and is not linked to constructive lifestyle a

39 s; and (4) private-well support programs are fragmented and lack sufficient resources.

40 ent interventions for nurses and midwives is fragmented and lacks cohesion.

41 the past decade, but these genomes are often fragmented and missing complex repeat regions.

42 ontact sites are decreased, mitochondria are fragmented and mitophagy is decreased.

43 uired biobanking infrastructure is currently fragmented and not prepared for the biobanking of microb

44 iterature on psychogenic amnesia is somewhat fragmented and offers little prognostic value for indivi

45 porting HIV programs were found to be highly fragmented and poorly integrated into national health sy

46 ensive transformation of the mineral in both fragmented and powder forms, precipitating manganese and

47 However, access to these predictors is fragmented and requires substantial effort to find them

48 ylococcus aureus as a prototype, we randomly fragmented and separately ligated the hemolysin gamma A

49 We find that mitochondria are small and fragmented and translocate apically on microtubules and

50 Importantly, new findings suggest that fragmented and unpredictable environmental and parental

51 Fragmented and unpredictable patterns of maternal care b

52 e in the private healthcare sector, which is fragmented and unregulated.

53 rategies for conservation in an increasingly fragmented and warmer world.

54 ization, theta oscillations were always more fragmented and with lower frequency.

55 nowledge of the insulin signaling network is fragmented, and because of the complexity of this networ

56 esised that elastin becomes disorganised and fragmented, and decreases in amount with ageing, especia

57 vated levels of reactive oxygen species, are fragmented, and do not aggregate normally at axonal bran

58 research on trophic rewilding is still rare, fragmented, and geographically biased, with the literatu

59 rvice reimbursement, leads to uncoordinated, fragmented, and low-quality HF care.

60 lasma is almost exclusively free DNA, highly fragmented, and not virion associated.

61 ortunately, the fossil record is partial and fragmented, and often cannot support validations for spe

62 EV-enclosed mRNAs are mostly fragmented, and UTRs enriched; nevertheless, some full-l

63 d a novel vector, MVA-B13R, by replacing the fragmented anti-apoptotic genes 181R/182R with a functio

64 Sahul is still poorly understood owing to a fragmented archaeological record.

65 stered in specific genes and associated with fragmented assemblies, but were reduced using the SKESA

66 otic genomes is imperfect, and errors due to fragmented assemblies, contamination, diverse gene famil

67 fficult to assemble and often lead to highly fragmented assemblies.

68 hort reads technologies produce accurate but fragmented assemblies.

69 ds to individual long DNA molecules that get fragmented at the same time (tagmentation).

70 Populations are fragmented at the southern edge of their distribution du

71 romised neuritic outgrowth, and contorted or fragmented axons with swollen varicosities containing al

72 atically improve contiguity in even our most fragmented base assembly.

73 ed capillaries with intercellular gaps and a fragmented basement membrane, facilitate delivery of mac

74 tlantic Forest of Brazil are two of the most fragmented biodiversity hotspots.

75 of collagen fingerprinting to more than 2000 fragmented bones from the site of Denisova Cave, Russia,

76 glaucoma patients demonstrate shorter, more fragmented bouts of physical activity throughout the day

77 m services to society(2), but they are often fragmented by barriers to free flow(3).

78 ring this period, New Zealand was repeatedly fragmented by glaciers into a series of refugia, with th

79 tion, from a complex mixture is isolated and fragmented by infrared multiphoton dissociation (IRMPD).

80 that these noncovalent complexes can also be fragmented by surface-induced dissociation (SID) followi

81 The electro-epoxidized products are then fragmented by tandem MS to generate diagnostic ions, ind

82 We aimed to identify habitat for a fragmented carnivore population at two scales and aid co

83 reaten population stability as seen in other fragmented carnivore populations globally.

84 of signal crayfish was higher in the highly fragmented catchment (River Medway).

85 of new colonisations in previously uninvaded fragmented catchments.

86 By making use of the plasmid-like fragmented chloroplast genome, we have introduced novel

87 egulation of Trex2, which was recruited into fragmented chromatin in keratinocytes that were undergoi

88 is work reveals that the interaction between fragmented chromogranin A and neuropilin-1 is required f

89 hin and composed of loose, disorganized, and fragmented collagen fibrils.

90 The land in Low Impact Areas is heavily fragmented, compromised by reduced patch size and core a

91 When forest is fragmented, cut, thinned, cleared or otherwise altered i

92 The fragmented data collected during the initial emergency l

93 ecific region directly in just 100 ng of non-fragmented denatured genomic DNA extracted from tomato s

94 tion with gag fused to the ubiquitin gene or fragmented, designed to increase CD8 magnitude and bread

95 le development, middle of the road, and more fragmented development), which each included six scenari

96 ies and social media outlets, resulting in a fragmented discourse.

97 umulation of damaged mitochondria, which are fragmented, display remodelled cristae and release cytoc

98 ater-obligate species with narrow, naturally fragmented distributions.

99 ssage through the G1/S transition, contained fragmented DNA, and underwent apoptosis.

100 assay, XACTLY, to interrogate the termini of fragmented DNA, information traditionally lost in standa

101 white spruce genome sequence remains highly fragmented, dozens of scaffolds encompassing more than o

102 Here, we show that a fragmented draft assembly is sufficient to perform mappi

103 , with decreased genetic diversity and often fragmented ecology, are then vulnerable to small stochas

104 imal and medial thickening, disorganized and fragmented elastic fibers, reduced smooth muscle calponi

105 In addition to showing reduced and fragmented elastic fibers, the histopathological hallmar

106 operties of the aortic wall characterized by fragmented elastic lamellae, whereas mice homozygous for

107 ry for annotation of structurally intact and fragmented elements.

108 have many features to suggest they represent fragmented ER, and some are physically separated from th

109 will be more diminished in size and heavily fragmented (especially in lowland wet forests), have red

110 g) to efficiently sequence both integral and fragmented exRNAs from a small droplet (5 muL to 7 muL)

111 be activated by endogenous alarmins such as fragmented extracellular matrix proteins found in degene

112 The presence of a fragmented FAZ did not affect visual acuity.

113 The presence of a fragmented FAZ seems not to be a rare phenotype in indiv

114 The frequency of a fragmented FAZ was 4.8% of individuals (12 of 250) or 3.

115 nts were found to have at least 1 eye with a fragmented FAZ.

116 found between the control eyes and eyes with fragmented FAZs for foveal pit depth, pit area, and tota

117 the basic mechanisms ruling the transport of fragmented fluids, such as foams and emulsions, remain e

118 tory infected coral systematically exhibited fragmented fluorescent pigments adjacent to the disease

119 The area of fragmented fluorescent pigments in diseased coral extend

120 ing potential, tri-trophic research has been fragmented, following two distinct paths.

121 ial carbon sink but is also the most heavily fragmented forest biome in the world.

122 es in bird-plant frugivory interactions in a fragmented forest landscape in Southwest China, with con

123 derstand orangutan movement in disturbed and fragmented forests of Malaysian Borneo.

124 llenges remain, in particular in coping with fragmented genes or genes evolving at different rates af

125 ods that are limited by culturing biases and fragmented genetic characterizations.

126 centromere type transition, we improved the fragmented genome assembly and constructed a chromosome-

127 ave so far been hampered because of a highly fragmented genome assembly.

128 s a well-studied problem, predicting BGCs in fragmented genomic assemblies remains challenging.

129 ge display library constructed from randomly fragmented genomic DNA coupled with affinity selection f

130 tly been documented using plasmid, viral, or fragmented genomic DNA; dPCR performance with more compl

131 c investigations, and assist the assembly of fragmented genomic sequences.

132 carry information about the structure of the fragmented glycans.

133 derived from all three individuals showed a fragmented Golgi that could be rescued by expression of

134 response, few have examined the effect that fragmented governance for health has had on effectively

135 The suburban site is characterized by a more fragmented habitat with more coniferous trees and less c

136 ing individuals' ability to disperse through fragmented habitat.

137 Where populations are fragmented, habitat quantification is often the first st

138 Altered river flows and fragmented habitats often simplify riverine communities

139 roles of livestock and wildlife as hosts in fragmented habitats, limiting the development of meaning

140 Endangered due to small population sizes and fragmented habitats.

141 In adsorption experiments fragmented HDPE bags c.

142 how it may be difficult to receive care in a fragmented health care model in which physician and hosp

143 rce, ageing and turnover of village doctors, fragmented health information technology systems, a pauc

144 , unequal distribution of resources, weak or fragmented health services, small population sizes that

145 In regions with scarce resources, fragile or fragmented health systems, cancer contributes to the cyc

146 socioeconomic inequalities and overwhelming fragmented health systems.

147 insect-pollinated tree species occurring in fragmented, highly-disturbed landscapes were investigate

148 went extensive fusion, but then subsequently fragmented in a pS473-KAP1-dependent manner.

149 the lowest mass-to-charge (m/z) ratio to be fragmented in the 2D MS experiment, which leads to precu

150 te that is readily generated, dispersed, and fragmented in the environment.

151 When ions are fragmented in the FT-IMS mode, the product ions maintain

152 expanded coverage by building onto a highly fragmented, inefficient, and costly health system.

153 of ontologies would not only make currently fragmented information about health risks from chemical

154 resence of integrated surface structure from fragmented input.

155 dered at many High Arctic sites by short and fragmented instrumental climate records.

156 ty phenotype; we observed abnormally long or fragmented intestinal nuclei due to aberrant nuclear div

157 in seawater chemistry throughout Hawai'i and fragmented into clonal replicates maintained under both

158 , with the highly conserved Atpalpha subunit fragmented into four separate pieces.

159 If these species are further fragmented into genetically isolated subpopulations, the

160 Cladophorales green algae, which is entirely fragmented into hairpin chromosomes.

161 e to moderate-intensity drought, as channels fragmented into isolated pools.

162 their role as cell protectants, can again be fragmented into MDA.

163 single circular molecules, these genomes are fragmented into multiple chromosomes in many eukaryotes,

164 tromeres frequently lost their integrity and fragmented into multiple lobes.

165 The isobarically labeled peptides are fragmented into sets of b- and y-ion clusters upon LC-MS

166 pulation of C. monodonta will become further fragmented into smaller populations, each of which will

167 es, the large subunit (LSU) ribosomal RNA is fragmented into two large and four small ribosomal RNAs

168 l surface remains roadless, but this area is fragmented into ~600,000 patches, more than half of whic

169 over, we also demonstrate that activation of fragmented IP3R1 can result in a distinct functional out

170 Its ability to measure fragmented junctions is unique.

171 In a two-year study, we determined whether fragmented kelp patches retained the ability to alter lo

172 Fragmented kinetochores were frequently abnormally attac

173 , while An. balabacensis was not, indicating fragmented land use could favour An. donaldi.

174 ith good colonization capacity in the highly fragmented landscape before the extinction of the popula

175 he Neotropical Magnolias in the context of a fragmented landscape still have ample gene flow within p

176 ion declines steeper in higher quality, less-fragmented landscapes (an inverse buffer effect) than in

177 frequencies in SW Finland resemble those in fragmented landscapes as opposed to continuous landscape

178 verting once large and persistent forests to fragmented landscapes of small kelp patches.

179 Fragmented landscapes that have more complex 3D vegetati

180 e applied to model more complex food webs in fragmented landscapes, broadening the scope of existing

181 capes while suspension feeders favoured more fragmented landscapes.

182 t forest loss is most detrimental in already fragmented landscapes.

183 ese declines is challenging in heterogeneous fragmented landscapes.

184 able landscapes and 200% farther in the most fragmented landscapes.

185 0 mm were analyzed for voltage and abnormal (fragmented/late potential) electrogram characteristics.

186 -dG adduct that can yield the imidazole ring-fragmented lesion, N(5)-NM-substituted formamidopyrimidi

187 nges of nondiadromous fish species were more fragmented (less connected) (CI = 73 +/- 28%; mean +/- S

188 With thermal activation, the fragmented ligands transform catalytically into closed-r

189 mbination of a flat free-energy landscape, a fragmented local structure, and the narrow temperature w

190 ebsites and apps and avoid further growth of fragmented, low-quality care.

191 he pyrochlore iridate Ho2Ir2O7, leading to a fragmented magnetization.

192 nformation was perceived to be scattered and fragmented, making it difficult to see the chronology of

193 ently (as elsewhere), protected areas suffer fragmented management, lack of a comprehensive classific

194 cies identifications of this rare and highly fragmented material.

195 o P11, a limited bedding model that leads to fragmented maternal care, was used to induce ELS.

196 tosis and accelerated atherosclerosis, sleep-fragmented mice with either haematopoietic CSF1 deficien

197 The fragmented mitochondria and accelerated wound closure of

198 analysis revealed a significant increase in fragmented mitochondria in the podocytes of wild-type di

199 (MN), led to phospho-Parkin accumulation in fragmented mitochondria resulting in mitophagy-induced m

200 ggested that loss of fusion capacity targets fragmented mitochondria to the pre-autophagic pool and u

201 On actin disassembly, fragmented mitochondria undergo rapid fusion, leading to

202 utant MxB or siRNA knockdown of MxB leads to fragmented mitochondria with disrupted inner membranes t

203 acetyltransferase (ChAT) enzyme expression, fragmented mitochondria, glial cell activation, muscle a

204 , altered expression of mitochondrial genes, fragmented mitochondria, impaired mitochondrial function

205 and cytoplasmic and axonal accumulations of fragmented mitochondria.

206 N2 downregulation and the presence of highly fragmented mitochondria.

207 Once fragmented, mitochondria that contain mutant genomes are

208 , suggesting that the massively expanded and fragmented mitochondrial genomes of S. noctiflora may ha

209 espan in C. elegans, and is accompanied by a fragmented mitochondrial network.

210 Livers from Mfn1LKO mice displayed a highly fragmented mitochondrial network.

211 highly connected versus those with a highly fragmented mitochondrial structure, suggesting the feasi

212 re authentic standards or databases of known fragmented molecules.

213 Results showed that the A2 assembly was less fragmented, more complete and more correct than A1.

214 tant individuals are currently restricted to fragmented mountain ranges on the eastern margin of the

215 We report that plasma contains fragmented mRNAs and lncRNAs that are missed by standard

216 we found that human plasma contains largely fragmented mRNAs from > 19,000 protein-coding genes, abu

217 er microplastics, the cubic ones mostly, are fragmented much faster than the parallelepipeds.

218 f Triton and most of them have probably been fragmented multiple times by cometary impacts(1-3).

219 1-F2 pre-assembled into amyloid oligomers or fragmented nanoscaled fibrils was highly cytotoxic.

220 suming, costly and low-yield and it produces fragmented nanosheets with submicrometre lateral dimensi

221 y the exonuclease activity of MRE11, and the fragmented nascent DNA accumulates in the cytosol, initi

222 These results highlight the exceptionally fragmented nature of CMV cfDNA and illustrate the promis

223 stems, arose is hindered by the scarcity and fragmented nature of genomes from key taxa, such as Pori

224 ucture often affect phenotypes, although the fragmented nature of most contemporary assemblies obscur

225 , residency in deprived, urban, and socially fragmented neighbourhoods was not associated with higher

226 in either neurons or glia have decreased and fragmented night sleep, indicative of a non-redundant re

227 euromuscular transmission at the most highly fragmented NMJs in the diaphragms of old (26-28 months)

228 gnificantly inhibits DNA synthesis, produces fragmented nucleoids, and alters membrane architecture.

229 steady-state morphology results in either a fragmented or elongated network, both of which are assoc

230 tightly bound lipids, and the complexes are fragmented or in physiologically irrelevant oligomeric s

231 e systems are in place, but most of them are fragmented or poorly coordinated.

232 ncluding large genomes, mtDNA recombination, fragmented organelles, and plastid/mitochondrial differe

233 ift northward and become more contracted and fragmented over time.

234 nd ipsilateral axons terminated in partially fragmented patches, forming a mosaic pattern of contrala

235 nd geographical barriers have created a more fragmented picture.

236 CHW programs for HIV in Southern Africa are fragmented, poorly integrated, and lack long-term suppor

237 emerge and persist despite an intrinsically fragmented population structure.

238 Demographic links among fragmented populations are commonly studied as source-si

239 to maintain migration and gene flow between fragmented populations, and to ensure the long-term pers

240 the nascent leading strand was artifactually fragmented postsynthesis by excision repair.

241 nanocomposites by producing what is called "fragmented products" (FP).

242 mice show evidence of sinus bradycardia and fragmented QRS complex, supporting the critical role of

243 onization can be improved through the use of fragmented quantitative standards.

244 teniposide coadministration greatly enhanced fragmented rAAV8 transduction at 48 h and 8 days.

245 he N4, N5, N6, and N8 NA subtypes using gene-fragmented random mutagenesis.

246 s, assembly software produces incomplete and fragmented reconstructions that require additional exper

247 Humans have fragmented, reduced or altered the biodiversity in tropi

248 financial and human-resource limitations and fragmented referral systems that prevent continuity of c

249 g indicating a surface composed of an impact-fragmented regolith overlying basaltic lava flows.

250 after a 5-day SF procedure that selectively fragmented REM sleep, cholinergic output neurons (ChNs)

251 ights into psychological disorders marked by fragmented REM sleep.

252 the reconstruction of coherent objects from fragmented representations in early visual cortex.SIGNIF

253 ened examples of a unitary memory system, or fragmented representations lacking aspects of healthy me

254 emanding and the assembled contigs are often fragmented, resulting in the identification of protein s

255 osed a novel algorithm to detect and restore fragmented ridges in incomplete fingerprints.

256 ry are especially strong in catchments where fragmented rocks are more exposed to weathering, and the

257 ebilitating human diseases, possess multiply fragmented rRNAs that together are analogous to 28S rRNA

258 of cis-regulatory architectures derives from fragmented sampling of large numbers of disparate molecu

259 d allowed for all-or-nothing orders to avoid fragmented share portfolios.

260 any isolate bacterial genomes as compared to fragmented short-read assemblies.

261 In humans and Drosophila, C3POs cleave the fragmented siRNA passenger strands and facilitate the ac

262 eparation of bone powder from the cochlea of fragmented skulls in which the petrous pyramid of the te

263 play changes in sleep homeostasis, including fragmented sleep and disturbances in delta power after s

264 Lower sleeping times and fragmented sleep are independently associated with an in

265 unrelated families corroborates late and/or fragmented sleep patterns in carriers, suggesting that i

266 racterized by reduced anxiety-like behavior, fragmented social behavior, and altered ultrasonic vocal

267 Highly fragmented social networks with cohesive subgroups are a

268 indicated reduced migration on the strongly fragmented southern riverside.

269 nd, but declined to extinction in the nearby fragmented southwestern (SW) Finnish archipelago in the

270 g population connectivity in conservation of fragmented species.

271 dead) we distinguished between complete and fragmented specimens.

272 te is distinct from sleep, (2) synchronously fragmented spiking pattern is a signature of anesthetic-

273 g increased frequencies of mispositioned and fragmented spindles.

274 different nature of the excitations in this fragmented state opens the way to tunable field-induced

275 led that modified okara particles had a more fragmented structure and a rougher surface than control.

276 own results in graph theory that exploit the fragmented structure of sparse network data.

277 munities inhabiting gypsum rocks with a more fragmented substrate architecture had higher taxonomic a

278 Bismuth oxide double-walled nanotubes with fragmented surface are prepared as a template, and are c

279 tissues and for specimens containing highly fragmented template DNA.

280 ent in a specimen, is compatible with highly fragmented templates, and can be readily implemented whe

281 ty isolated in a first drift region and were fragmented to carbocations at 64 to 128 Td and 45 to 89

282 llapses of non-aerial dispersers as channels fragmented to irruptions of small, eurythermic dietary g

283 ble bear habitat has not become sufficiently fragmented to restrict movement of individuals.

284 ered genome assembly and cannot be used with fragmented, un-scaffolded draft genomes, limiting its ap

285 aryotic transfer RNAs can become selectively fragmented upon various stresses, generating tRNA-derive

286 hase liquid chromatography (LC)-MS, and then fragmented using electron-transfer/higher-energy collisi

287 stitution at Ser-331 increased the number of fragmented vacuoles.

288 ubstrate (AES) as characterized by prolonged fragmented ventricular potentials.

289 apparent reduction in background noise, and fragmented vessels in the images before averaging became

290 and PC yielded ethylated [PC(Tr)](+), which fragmented via MS/MS to produce a high-intensity charact

291 often studied in isolation, thereby giving a fragmented view of the life cycle as a whole.

292 disordered loop, and this has resulted in a fragmented view of the protein's biological activity.

293 cognitive mapping benefits of counteracting fragmented visibility.

294 ut the brain causes excessive sleepiness and fragmented wakefulness during the nocturnal active phase

295 ain pervasive assembly errors and are highly fragmented, which limits their values.

296 Care is fragmented with poor interdisciplinary collaboration and

297 h and N50 subread length of 11 kb are highly fragmented, with even low-copy genic regions showing deg

298 ies with therapeutic expertise are typically fragmented, with major elements missing in thousands of

299 However, these assemblies are highly fragmented, with many gaps, ambiguities, and errors, imp

300 y increased but also highly disorganized and fragmented within large and small asthmatic airways comp