ライフサイエンスコーパス: freely behaving

1 neurons to hypercapnia and arousal state in freely behaving adult male and female mice using the cal

2 orded in neonatally isolated and non-handled freely behaving adult male rats.

3 inhibits LTP, but not LTD at MF synapses of freely behaving adult rats.

4 uditory cortex (areas Te1, Te1v, and Te3) of freely behaving, amygdalectomized rats using a movable b

5 ks can estimate two-dimensional (2D) pose in freely behaving and tethered animals.

6 l integration may be reliably estimated in a freely behaving animal in its natural habitat and that w

7 nd neuropharmacological information from the freely behaving animal shows great promise for further i

8 ar manipulation of membrane potential in the freely behaving animal to perturb the dynamics within a

9 Here, using optogenetics in the freely behaving animal, we examined exploratory behavior

10 encoding throughout the nervous system of a freely behaving animal.

11 Electrophysiological recordings from freely behaving animals are a widespread and powerful mo

12 d behavior, but tools to modulate neurons in freely behaving animals are limited.

13 In conscious freely behaving animals blockade of Ca(2+)-dependent ves

14 genetic reduction of cholinergic activity in freely behaving animals disrupted odor discrimination of

15 on of estradiol in the auditory forebrain of freely behaving animals disrupts behavioral responses to

16 the superior colliculus and barrel cortex of freely behaving animals during active exploration, awake

17 Hippocampal pyramidal neurons in freely behaving animals exhibit spatially selective firi

18 e soft implants extracted cortical states in freely behaving animals for brain-machine interface and

19 ies that demand the use of unconstrained and freely behaving animals in isolation or in social groups

20 the intricate dynamics of neural activity in freely behaving animals is essential for understanding t

21 sonance translates into spiking resonance in freely behaving animals is unknown.

22 ulation, single-cell fluorescent dynamics in freely behaving animals larger than mice remains a key e

23 anization of dopamine (DA) release events in freely behaving animals relies on a set of characteristi

24 Interrogating these phenomena in freely behaving animals requires a portable microscope w

25 f thalamocortical synaptic efficacy in V1 of freely behaving animals revealed stable responses across

26 To enable translaminar imaging in freely behaving animals through implanted microprisms, w

27 h correlates reasonably well with the period freely behaving animals were found to crawl after they s

28 We combined chronic electrophysiology in freely behaving animals with an eye-reopening paradigm t

29 We hypothesized that SC activity in freely behaving animals would reveal dynamic shifts in n

30 rfaces hinder long-term studies in awake and freely behaving animals, as they are limited in their ab

31 ned with manipulation of specific neurons in freely behaving animals, can help advance this field.

32 ojections at particular times, either within freely behaving animals, or in reduced preparations such

33 veloped a novel methodology that enabled, in freely behaving animals, simultaneous unit recording and

34 elemetry system to simultaneously record, in freely behaving animals, the activity of the DCMD and of

35 that can control neural circuit activity in freely behaving animals, thus extending the scope of two

36 However, the motion of freely behaving animals, together with the intermittent

37 In freely behaving animals, we find that the DA signal from

38 lows effective recording of brain signals in freely behaving animals.

39 deoxyglucose (2DG) method was carried out in freely behaving animals.

40 dy sensory-induced gene expression in awake, freely behaving animals.

41 nucleus (CN) have not been studied in awake, freely behaving animals.

42 monitored jumps evoked by looming stimuli in freely behaving animals.

43 mpal correlates of space ("place fields") in freely behaving animals.

44 h patterns of activity that were recorded in freely behaving animals.

45 motor control, and sensorimotor learning in freely behaving animals.

46 s of the somatic and dendritic potentials in freely behaving animals.

47 hod for recording in vivo neural activity in freely behaving animals.

48 trunk, and limbs for week-long timescales in freely behaving animals.

49 at simultaneously records two wavelengths in freely behaving animals.

50 opioid peptide signal dynamics in tissue and freely behaving animals.

51 led the measurement of brainwide dynamics in freely behaving animals.

52 able traction for in vivo calcium imaging in freely behaving animals.

53 events from a large population of neurons in freely behaving animals.

54 vision enable tracking the pose (posture) of freely behaving animals.

55 first description of GnRH neuron activity in freely behaving animals.

56 tor the activity of distant brain regions in freely behaving animals.

57 bcortical genetically targeted cell types in freely behaving animals.

58 s from distributed populations of neurons in freely behaving animals.

59 ovel hypotheses concerning brain function in freely behaving animals.

60 ranges with digital control and telemetry in freely behaving animals.

61 tissue, precluding their noninvasive use in freely behaving animals.

62 ty and local tissue oxygen were performed in freely behaving animals.

63 e heralds a new era in functional imaging of freely behaving animals.

64 of targeted sets of neurons in the brains of freely behaving animals.

65 f fluids and light into the brains of awake, freely behaving animals.

66 mounted miniature microscopes for imaging in freely behaving animals.

67 or minimally invasive, untethered studies on freely behaving animals.

68 respond to a given odorant ligand in awake, freely behaving animals.

69 rocorticographic recordings were acquired in freely behaving animals.

70 While electrodes allow for recording in freely-behaving animals, they tend to be bulky and stiff

71 's effects on hippocampal function in awake, freely-behaving animals.

72 opes and in vivo neural imaging in awake and freely-behaving animals.

73 bling real-time functional neural imaging in freely-behaving animals.

74 Injection of CP2 into freely behaving Aplysia increases the rate of respirator

75 We show that freely behaving bats constantly control their biosonar f

76 rom the majority of neurons in the head of a freely behaving Caenorhabditis elegans with cellular res

77 tive principal (i.e., excitatory) neurons in freely behaving cats across periods of waking MD and pos

78 In vivo microdialysis measurements in freely behaving cats showed that adenosine extracellular

79 posterior suprasylvian gyrus (vPS cortex) of freely behaving cats was reversibly deactivated with coo

80 tivity with anatomical specificity in awake, freely behaving conditions using reliable methods.

81 their activity patterns, particularly under freely behaving conditions.

82 Further, in vivo recordings in freely behaving control rats exposed to playback showed

83 In conscious, freely behaving females, three infusions of an excitator

84 of electric signaling patterns recorded from freely behaving fish revealed that the IPI and direction

85 We validated LEAP using videos of freely behaving fruit flies and tracked 32 distinct poin

86 s into or out of a phasic firing mode in two freely behaving genetic rodent models of absence epileps

87 y rhythm in the output of 5-HT in the SCN of freely behaving hamsters.

88 e obtained between 2 and 12 months of age in freely behaving HI-treated and sham control rats.

89 Analyzing the retinal input of freely behaving human subjects showed that the distribut

90 ble aspects of vestibular function in intact freely behaving human subjects.

91 aneous neocortical local field potentials in freely behaving infant rats during natural interactions

92 Recordings in freely behaving intact male and female mice revealed abr

93 In freely-behaving larval zebrafish, fentanyl depresses the

94 We used multisite in vivo neurophysiology in freely behaving male and female C57BL/6 mice (n = 12) to

95 evokes responses from 144 ORs and 3 TAARs in freely behaving male and female mice, the first example

96 Using miniscopes in freely behaving male and female mice, we found optogenet

97 vivo calcium imaging and taste reactivity in freely behaving male and female Sprague Dawley rats to e

98 toallosterically to induce SWS in the NAc of freely behaving male mice by increasing the activity of

99 Employing dual-site in vivo recording in freely behaving male mice, here we show that hippocampal

100 tering of LH neurons firing rate dynamics in freely behaving male mice, we identified distinct popula

101 in the perirhinal cortex (PRC) and in AC of freely behaving male rats across wakefulness and sleep.

102 s measured at the individual neuron level in freely behaving male rats change as a function of vigila

103 cal recordings in dorsal hippocampal CA1, in freely behaving male rats experiencing changes to reward

104 ation of Schaffer-collateral-CA1 synapses of freely behaving male rats, in conjunction with VTA stimu

105 ze LFP signals presumptively from the HVC of freely behaving male zebra finches during song productio

106 urons with appropriate temporal precision in freely behaving mammals, the causal role of these action

107 paminergic neuron action potential firing in freely behaving mammals.

108 s, we describe breathing behaviors in awake, freely behaving marmosets.

109 In 10 freely behaving MCH-cre mice (male and female), the high

110 Using a miniature microscope in freely behaving mice and a two-photon microscope in head

111 osure to the peptide also stimulates VSNs in freely behaving mice and drives innate avoidance.

112 d calcium activity using fiber photometry in freely behaving mice and found arousal-state-dependent a

113 We genetically mark active neurons of freely behaving mice at four times of the day with a c-F

114 anges in neuronal activity of ACC neurons in freely behaving mice during early learning.

115 R can be used to detect serotonin release in freely behaving mice during fear conditioning, social in

116 unit and population neural activity in LC of freely behaving mice during their interactions with pups

117 imaging and neural activity manipulation in freely behaving mice encountering noxious stimuli, we id

118 dm(SF1) neurons at single-cell resolution in freely behaving mice exposed to a natural predator in va

119 on of breathing pattern in anaesthetized and freely behaving mice in normoxia, hypoxia and hypercapni

120 esthetized mice with high f ( 2.5 Hz) and in freely behaving mice in normoxia, hypoxia or hypercapnia

121 sthetized mice with high f (>=2.5 Hz) and in freely behaving mice in normoxia, hypoxia or hypercapnia

122 ry mouse neurons, as well as in the brain of freely behaving mice in vivo to mediate reversible modul

123 activation of Mrgprb4-expressing neurons in freely behaving mice promoted conditioned place preferen

124 r recordings of PVN CRF neuronal activity in freely behaving mice revealed that CRF neurons are activ

125 In vivo dopamine and calcium imaging in freely behaving mice revealed that this dopaminergic pro

126 lcium dynamics of hippocampal CA1 neurons in freely behaving mice subjected to trace fear conditionin

127 corded neural activity in the hippocampus of freely behaving mice that had a forebrain-specific knock

128 Using Ca(2+) imaging in freely behaving mice that repeatedly explored a familiar

129 here a variety of optogenetic approaches in freely behaving mice to evaluate the role of the arcuate

130 Employing in vivo calcium imaging in freely behaving mice to record activity dynamics from hu

131 strates that tooth pain can be quantified in freely behaving mice using approaches common for other t

132 of glutamatergic MnPO neuron stimulation in freely behaving mice while monitoring drinking behaviour

133 d multiple electrode recording techniques to freely behaving mice with a CA1 pyramidal cell-specific

134 g hormone (GnRH) pulse generator activity in freely behaving mice with GCaMP photometry demonstrated

135 We mapped behavioral responses in freely behaving mice with specific nociceptor and low-th

136 nt-and-tether-free deep-brain stimulation in freely behaving mice with stereotactically injected macr

137 In freely behaving mice, activation of these neurons in the

138 We show that in freely behaving mice, astrocytes in the nucleus accumben

139 wake state alongside PER2 bioluminescence in freely behaving mice, demonstrating that PER2 biolumines

140 ess S based on cortical activity recorded in freely behaving mice, describing local Process S as a fu

141 For freely behaving mice, our results show that information

142 for normal odor sensation and adaptation of freely behaving mice, preventing saturation of the olfac

143 the role of nociceptive sensory afferents in freely behaving mice, we developed a fully implantable,

144 Using longitudinal calcium imaging in freely behaving mice, we find that corner cells tune the

145 Using longitudinal calcium imaging in freely behaving mice, we find that unlike the associativ

146 oton imaging ex vivo and fiber photometry in freely behaving mice, we found that acute EAE was associ

147 Using in vivo calcium imaging in freely behaving mice, we found that inhibitory neurons i

148 Using imaging methods in freely behaving mice, we found that the activity of neur

149 For whole-cortex imaging in freely behaving mice, we present the 'mini-mScope', a wi

150 Using calcium imaging fiber photometry in freely behaving mice, we show that PPT neurons sharply a

151 neurons for 1 min generated pulses of LH in freely behaving mice, whereas inhibition with archaerhod

152 studying selective visuospatial attention in freely behaving mice.

153 es susceptibility to social-defeat stress in freely behaving mice.

154 ly identified VTA-projecting BNST neurons in freely behaving mice.

155 manual annotations of thousands of clips of freely behaving mice.

156 cence microscopes now allow brain imaging in freely behaving mice.

157 e of minutes in specific brain subregions of freely behaving mice.

158 m genetically identified cell populations in freely behaving mice.

159 of over months when chronically implanted in freely behaving mice.

160 PFC) encode anxiogenic environmental cues in freely behaving mice.

161 aptic drive onto inhibitory neurons (E I) in freely behaving mice.

162 ssential roles for esophageal peristalsis in freely behaving mice.

163 e precise treatment of deep brain tumours in freely behaving mice.

164 l for simultaneous, multimodal recordings in freely behaving mice.

165 ameras, polysomnography, and GECI imaging in freely behaving mice.

166 g using the mini-MCAM in both head-fixed and freely behaving mice.

167 d fluorophore GCaMP6 with concomitant LFP in freely behaving mice.

168 subcellular Ras activities in the brains of freely behaving mice.

169 dopsin channels by performing stimulation in freely behaving mice.

170 sed to validate stable chronic recordings in freely behaving mice.

171 apidly suppresses BLAPCs and BLA activity in freely behaving mice.

172 the real-time activity of individual DGCs in freely behaving mice.

173 ls from many brain regions simultaneously in freely behaving mice.

174 gs performed in in vitro preparations and in freely behaving mice.

175 aminergic activity during sexual behavior in freely behaving mice.

176 dynamics of genetically specified neurons in freely behaving mice.

177 y out longitudinal studies of brain aging in freely behaving mice.

178 or in one set of experiments using awake and freely behaving mice.

179 fic phases of the endogenous theta rhythm in freely behaving mice.

180 midal neurons in the primary motor cortex of freely-behaving mice, providing opportunities to define

181 esolution imaging at high speeds (26 fps) in freely-behaving mice.

182 ly representative of spontaneous grooming in freely-behaving mice.

183 paws during spontaneous grooming in multiple freely-behaving mice.

184 ositron emission tomography (FDG-PET) in 238 freely behaving monkeys identified brain regions where m

185 Freely-behaving mosquitoes deposit saliva droplets by bi

186 ium imaging across the sleep-wake cycle in a freely behaving mouse model of AD before Abeta plaques a

187 acellular spike activity in two symptomatic, freely behaving mouse models: R6/2 transgenics, which ar

188 ehavioral elements and their patterns in the freely behaving mouse.

189 so noted during locomotion video tracking of freely behaving mutants.

190 we monitored cortical neuron populations in freely behaving nonhuman primates during natural locomot

191 Investigation of freely behaving organisms (not in laboratory tasks) sugg

192 single or multiple electrodes implanted in a freely behaving primate.

193 ion between two sites in the motor cortex of freely behaving primates.

194 elates could drive naturalistic behaviors in freely behaving primates.

195 ion (V E) in 5-d, 10-d, and 15-d-old intact, freely behaving rat pups, using whole-body plethysmograp

196 n vivo calcium imaging of CA1 place cells in freely behaving rats (n = 14).

197 We used bilateral microdialysis in freely behaving rats (n = 32), instrumented for electroe

198 Here we show that in freely behaving rats after a long period in an awake sta

199 nucleus (LMN) and anterior thalamus (ATN) of freely behaving rats and also made bilateral lesions of

200 f neurons in the medial prefrontal cortex of freely behaving rats are phase locked to the hippocampal

201 sis in individual visual cortical neurons in freely behaving rats as they cycled between sleep and wa

202 Therefore, we analyzed data from freely behaving rats as well as data from the speed-clam

203 (TRN) and medial prefrontal cortex (mPFC) of freely behaving rats at rest to investigate thalamocorti

204 microstimulation within the motor cortex of freely behaving rats before and after striatal disinhibi

205 ensory-affective experiences in real time in freely behaving rats by coupling neural codes for nocice

206 d cortical imaging and has been validated in freely behaving rats by simultaneously imaging >1000 GCa

207 In this study, we investigated whether freely behaving rats can discriminate fine tactile patte

208 We recorded neurons from the hippocampus of freely behaving rats during an auditory fear conditionin

209 to monitor firing rates in visual cortex of freely behaving rats during chronic monocular visual dep

210 Single neurons were recorded in freely behaving rats during fear conditioning from areas

211 subnucleus of the lateral amygdala (LAd) of freely behaving rats during Pavlovian fear conditioning,

212 nge on electrophysiological data recorded in freely behaving rats during REM sleep, both before and a

213 twork spiking in visual cortical circuits in freely behaving rats for 9 days.

214 of the unique capabilities of this device in freely behaving rats forecasts its broad and practical u

215 We found that the forelimb stepping cycle in freely behaving rats is rhythmic and peaks at around 8 H

216 Focal disinhibition of the NAc core in freely behaving rats led to macro-scale hyperactivity an

217 tive distal-most dendrites using tetrodes in freely behaving rats over multiple days with a high degr

218 Using in vivo calcium imaging in freely behaving rats over the course of learning, we fou

219 vity and sensory evoked field potential from freely behaving rats previously implanted with permanent

220 d potentials recorded from the PFC and CN in freely behaving rats previously implanted with permanent

221 Freely behaving rats previously implanted with semi-micr

222 To test this hypothesis, freely behaving rats received bilateral intrastriatal in

223 ivo time-lapse endoscopic calcium imaging in freely behaving rats showed that OT selectively enhanced

224 n the dentate gyrus (DG) of anesthetized and freely behaving rats that both acute as well as chronic

225 ain slices as well as implanted in brains of freely behaving rats to demonstrate their ability to mai

226 Here, we use chronic electrophysiology in freely behaving rats to follow individual V1 neurons acr

227 titial glucose concentrations in the body of freely behaving rats to identify an activity pattern tha

228 ialysis in the dorsal raphe nucleus (DRN) of freely behaving rats to study the effect of GABA and glu

229 dings were obtained in the basal amygdala of freely behaving rats undergoing simultaneous reward, fea

230 rahippocampal microdialysis was performed in freely behaving rats, and the firing of single neurons i

231 (HP) and medial prefrontal cortex (mPFC) of freely behaving rats, following 5-MeO-DMT administration

232 In contrast, here we show that in freely behaving rats, theta oscillations in area CA1 are

233 In freely behaving rats, VTA GABA neurons were relatively f

234 Using multisite recordings in freely behaving rats, we examined gamma oscillations wit

235 When we used multi-site recordings in freely behaving rats, we observed ripples throughout the

236 arge ensembles of hippocampal place cells in freely behaving rats, we observed that replay content is

237 neuron activity continuously for 10-14 d in freely behaving rats, we show that normal waking experie

238 ), a key area for processing pain affect, in freely behaving rats.

239 pus, medial septum, and anterior thalamus of freely behaving rats.

240 monitoring of multiple neurotransmitters in freely behaving rats.

241 eptors in the PF-LHA on sleep-wakefulness in freely behaving rats.

242 cortex using fixed-potential amperometry in freely behaving rats.

243 lar serotonin in the dorsal raphe nucleus of freely behaving rats.

244 ections of TTX into RPO and SubC on sleep in freely behaving rats.

245 sis and measurement of locomotor activity in freely behaving rats.

246 cholinergic region of the basal forebrain of freely behaving rats.

247 heir cardiorespiratory effects in conscious, freely behaving rats.

248 HD cells were recorded from AD in freely behaving rats.

249 l deep brain stimulation (DBS) of the PFC in freely behaving rats.

250 supporting up to 1,024 recording channels in freely behaving rats.

251 using deep brain in vivo calcium imaging in freely behaving rats.

252 7 mm), cellular resolution neural imaging in freely behaving rats.

253 functions of the hippocampus from studies in freely behaving rats.

254 cellular identification of single neurons in freely behaving rats.

255 identification of single layer 3 neurons in freely behaving rats.

256 ampal place-cell and interneuron activity in freely-behaving rats.

257 stributed across multiple cortical areas, in freely behaving rhesus monkeys.

258 of-concept long-term wireless recording in a freely behaving rodent.

259 tudies by using a proxy signal for BOLD in a freely behaving rodent.

260 fUS is capable of imaging head-fixed or freely behaving rodents and of producing volumetric imag

261 of neurons in primary visual cortex (V1) of freely behaving rodents are similar during prolonged per

262 hanges in higher-order network properties of freely behaving rodents during prolonged visual deprivat

263 and analysis of heart rate and behaviour in freely behaving rodents over weeks This system can be us

264 Using multisite optogenetic manipulations in freely behaving rodents, we found that depolarization of

265 ons (PV) in the hippocampus and neocortex of freely behaving rodents.

266 r activity, heart rate, and head movement in freely behaving rodents.

267 firing rate homeostasis in the neocortex of freely behaving rodents.

268 tiparametric physio-behavioral monitoring in freely behaving small animals and interacting groups.

269 Here, we characterized, in freely behaving Sprague Dawley male rats, the MD neural

270 c device for neuromodulation of the complete freely behaving subject.

271 for the interrogation of neural dynamics in freely behaving subjects, without limitations set by fib

272 ecord cortical spreading depression (CSD) in freely behaving subjects.

273 y GABA dose; and the method can be used with freely behaving subjects.

274 In the present work we show, in freely behaving SUDEP-prone transgenic mice, that apnea

275 ound that individual sensorimotor neurons in freely behaving swamp sparrows expressed categorical aud

276 hippocampus, we have recorded place cells in freely behaving, transgenic mice that express a mutated

277 rrelates, during a seizure on unanesthetized freely behaving unrestrained animals.

278 ues for monitoring neural activity in awake, freely behaving vertebrates are invasive and difficult t

279 ion, we recorded neural firing in the LHb of freely behaving, water-deprived rats before and after an

280 1 neurons in a mixed-sex group of five to 10 freely behaving wild Egyptian fruit bats that lived cont

281 ciplinary approach to map neural circuits in freely behaving worms by integrating functional imaging,

282 activity of genetically specified neurons in freely behaving zebrafish.