ライフサイエンスコーパス: frequent

1 in which these genomic alterations are most frequent.

2 asional (1 SSB serving/mo to <1 serving/wk), frequent (1 SSB serving/wk to <1 serving/d), and daily (

3 L2307F is more frequent (4%) among Ashkenazi Jewish populations.

4 e found di-nucleotide repeat motif were more frequent (4684) within 0.14 gb (giga bases) transcriptom

5 en the groups, with hypoactive delirium most frequent (61%), followed by mixed delirium (39%).

6 le base substitutions predominated including frequent A:A (template: dNMP) mispairings.

7 in vivo models and discovered that the most frequent Aalpha R183W mutation formed alternative holoen

8 ronic rhinosinusitis (CRS) is complicated by frequent acute exacerbations leading to significant heal

9 Tubulointerstitial lesions were frequent: acute tubular injury (94%), tubulitis (82%), t

10 The most frequent adverse event was fatigue with a pooled prevale

11 and autoimmune disease were associated with frequent AECRS with statistically significant adjusted o

12 Overall, GCs were frequent after 3 (DM: 53.9%; EM: 69.2%) and 6 months (DM

13 lthough early vomiting (within 1 h) was more frequent after dihydroartemisinin-piperaquine plus meflo

14 GSOC tumors exhibit genomic instability with frequent alterations in the protein kinome; however, onl

15 Endocarditis was 10-fold more frequent among iGAS patients with documented IDU only ve

16 Depression is more frequent among individuals exposed to traumatic events.

17 Coronary artery disease (CAD) is more frequent among individuals with dysglycemia.

18 ated triglycerides and prediabetes were more frequent among LRRK2 carriers, MS does not seem to influ

19 Cannabis use is frequent among people living with human immunodeficiency

20 Polypharmacy was more frequent among PLWH across all age groups except those a

21 COVID-19 is frequent among the KT population.

22 224 breeds, both FTSJ3 and GH1 variants are frequent among very small "toy" breeds and absent from l

23 erythropoiesis and lymphopoiesis, leading to frequent anaemia and decreased adaptive immunity.

24 Autophagic vacuoles, as well as frequent and extensive deposits of lipoproteins, includi

25 e gamma model reduced the proportion of both frequent and infrequent hitters relative to the BSF.

26 decades, the Caribbean region has undergone frequent and intense heat waves, storms, floods, and dro

27 lth, productivity, and well-being, with more frequent and intense heatwaves projected to increase exp

28 low river flows are predicted to become more frequent and more severe across many global regions as a

29 dence of, and to effectively treat, the most frequent and most lethal complications.

30 tial to form secondary DNA structures pose a frequent and significant impediment to DNA replication a

31 ted neuropsychological tests, the finding of frequent and unexpected failure in a range of clinical c

32 Co-reactivity to more than one nut is frequent, and co-sensitization in the absence of clinica

33 Early, frequent, and scheduled family meetings combined with a

34 0 to 100, with higher scores indicating less frequent angina and better function and quality of life)

35 ck and vermin living in close proximity; (2) frequent antibiotic misuse; and (3) insufficient drinkin

36 that, throughout the winter, Bewick's swans frequent areas where air temperatures are c.

37 t episodes, which are becoming as severe and frequent as droughts, are overlooked and their impacts r

38 Esotropia was twice as frequent as exotropia, and 2 participants had paralytic

39 ces risk of outbreaks, but may need to be as frequent as twice weekly.

40 Their frequent association with mechanosensitive functions sug

41 A frequent assumption in value-based decision-making tasks

42 deaths were rare early post-transplant, but frequent at later time points (0.93 per 100 patient-year

43 rences of past-year nonmedical cannabis use, frequent (at least three times a week) nonmedical use, a

44 iagnosed in 16 patients (36%), with the most frequent being Waldenstrom macroglobulinemia (n = 9, 20%

45 However, eye tears and frequent blinking limit drug retention on the ocular sur

46 ies can compensate by taking larger and more frequent blood meals.

47 SHH-medulloblastoma (MB) is among the most frequent brain tumors in children less than 3 years of a

48 Poor outcomes for hospitalized PLWH were frequent but similar to proportions in comparators; 18%

49 tocellular carcinoma (HCC) is the third most frequent cause of cancer-related death.

50 mirabilis is a Gram-negative uropathogen and frequent cause of catheter-associated urinary tract infe

51 e pancreas and it represents the fourth most frequent cause of death in cancer-related disease, with

52 iant of frontotemporal dementia (bvFTD) is a frequent cause of early-onset dementia.

53 n cause soft tissue infections but is also a frequent cause of foodborne illnesses.

54 The most frequent cause of portal hypertension is cirrhosis.

55 At the same time, S. aureus is the most frequent cause of skin and soft tissue infections.

56 ogenic variants in STXBP1 are among the most frequent causes of neurodevelopmental disorders includin

57 of PBRM1 mutations and angiogenesis markers, frequent CDKN2A/B alterations, and increased PD-L1 expre

58 Batch effect is a frequent challenge in deep sequencing data analysis that

59 A gene, located at 11q23, are among the most frequent chromosome aberrations in acute myeloid leukemi

60 Strabismus is a frequent chronic eye condition that is associated with a

61 r analysis of daily wind patterns shows more frequent circulation regimes that steer landfalling TCs

62 provides evidence that there is unexpectedly frequent co-transmission of related parasites in the int

63 Beyond their frequent coexistence arising from their high prevalence

64 This suggests the frequent coexistence of multiple breast cancer states wi

65 COX inhibitors are also frequent cofactors in anaphylaxis.

66 ally challenging and necessitating clear and frequent communication with the surgical team in order t

67 gher BMI and HbA1c, less severe TB, and more frequent comorbidities, DM complications, and hypertensi

68 Obesity was the most frequent comorbidity exhibited by coronavirus disease 20

69 in the setting of septic shock, and the most frequent comparator was a combination of norepinephrine

70 One possibility is that flies perform frequent comparisons between anterior and posterior sens

71 Acute kidney injury is a frequent complication in this population and negatively

72 Osteoarticular disease is a frequent complication of human brucellosis.

73 Anemia is a frequent complication of kidney disease.

74 Acute kidney injury (AKI) is a frequent complication of traumatic injury; however, long

75 ac arrhythmias are demonstrated along with a frequent concomitant treatment with several QT-prolongin

76 n-alcoholic fatty liver disease (NAFLD) is a frequent condition in obese patients and regularly progr

77 Viral or idiopathic pericarditis is a frequent condition, often considered benign, although pr

78 tive if patients and providers can adhere to frequent, consistent follow-up so antiviral therapy may

79 Frequent consumption of nuts and/or dried fruits is high

80 Frequent contact between stakeholders and advisors is sh

81 gimens for AIDS-associated Kaposi sarcoma, a frequent contributor to morbidity and mortality among pe

82 rest (34.3% versus 35.7%), and received less-frequent coronary angiography (78.3% versus 81.4%), earl

83 nvestigation of sulfur metabolism elucidates frequent cross-compartment exchange of a standing pool o

84 In a stratified analysis, more frequent cumulative SSB consumption was positively assoc

85 mobile clamp formation event, MutS undergoes frequent cycles of mismatch rebinding and mobile clamp r

86 osensor chip offers considerable promise for frequent decentralized testing of I and C towards a tigh

87 The frequent deregulation of MYC and its elevated expression

88 The most frequent diagnoses were symptom-based descriptions of ch

89 Our findings indicate frequent discontinuations of checkpoint inhibitors at on

90 S) and lactose intolerance (LI) are two very frequent diseases.

91 eep disorders that are often associated with frequent disturbances to human rest/activity patterns.

92 The most frequent DNMT3A mutation in AML patients (R882H) encodes

93 rotection against all bleed types, with less frequent doses.

94 Early treatment and frequent dosing in the real-world setting may be the key

95 pyrimethamine (8 g, -9 to 26), although more frequent dosing increased the antimalarial effect (31 g,

96 nsification of rainfall cycles, ranging from frequent downpours to severe droughts, could cause wides

97 As storms become increasingly intense and frequent due to climate change, we must better understan

98 ich sequences cluster by species, suggesting frequent duplication and/or gene conversion events.

99 Recent data suggest that frequent endoscopy and biopsy without evidence of graft

100 f ozone have decreased but remain stubbornly frequent even as the ozone precursors NO(x) (nitrogen ox

101 .3%), with secondary fracture being the most frequent event (1.8% [four of 217]).

102 f this signalling network is one of the most frequent events in human cancer and serves to disconnect

103 ified, 600 (19.3%) were classified as having frequent exacerbation.

104 ease classification system (P = .0015), more frequent exacerbations (P = .0042), blood eosinophil lev

105 pulmonary disease (COPD) is characterized by frequent exacerbations.

106 n patients with severe asthma and those with frequent exacerbations.

107 not expected until RCP 4.5 or greater, while frequent exposure to low DO is already occurring.

108 Current models of HIV service delivery, with frequent facility visits, have led to facility congestio

109 Other frequent features included perisylvian polymicrogyria, a

110 Elevated qAF(8) values were a frequent finding (n = 105 [45%]) and associated with ABC

111 found that intracranial calcifications are a frequent finding in all arterial beds with the highest p

112 Additional frequent findings included renal proximal tubular injury

113 Resprouters were associated with less frequent fire than seeders.

114 Increasingly, frequent fires caused by regional dry and warming trends

115 timber and land for agriculture, leading to frequent fires in the region.

116 the patients with a second tumour, the most frequent first primary tumours were melanoma (eight pati

117 er frequency populations do exist because of frequent first-cousin marriages and/or a higher mutation

118 All taxa exhibited frequent flights on southerly winds, accounting for the

119 More frequent follow-up and diligent home monitoring is recom

120 pseudophakic RD, including greater age, more frequent foveal detachment, PVR, and greater RD extent.

121 site was absent at that time, becoming more frequent from about 1.35 Ma, as the Northern Hemisphere

122 Treatment switches, albeit low, were more frequent from ranibizumab to aflibercept than vice versa

123 HIV migration was more frequent from San Diego county towards Tijuana than vice

124 The most frequent genetic alterations across multiple human cance

125 Noonan syndrome (NS) is one of the most frequent genetic disorders.

126 bp insertion (type II mutation) are the most frequent genetic lesions.

127 The most frequent grade 3-4 adverse events were thrombocytopenia

128 t eliminate HIV reservoirs, resulted in more frequent grade 4 neutropenia and thrombocytopenia, and d

129 these symptoms persist for years and lead to frequent health care use; for some, fibromyalgia and its

130 gest human activity fueled stronger and more frequent heatwaves through greater evaporative drying in

131 a cell cancer and represents the second most frequent hematologic malignancy.

132 More frequent hematologic toxicity resulted in more reduced d

133 The most frequent histologies were osteosarcoma (n = 6), inflamma

134 g binomial survivor function (BSF) model of "frequent hitters" using 872 publicly available HTS data

135 um with no clear boundary between normal and frequent hitting compounds.

136 e clinical benefit and cost-effectiveness of frequent HIV screening among high-risk YMSM from age 15.

137 Frequent horizontal gene transfer and chromosomal integr

138 lop a number of complications that result in frequent hospital admissions and high morbidity and mort

139 Four frequent 'hotspot' PIK3CA mutations (E542K, E545K, H1047

140 e use of high-risk chemotherapy regimens and frequent HSCT upon first remission.

141 We prospectively enrolled 19 patients with frequent IA (>=6 episodes/y) who then underwent a medica

142 The most frequent IEIs sharing common main clinical problems requ

143 local prevalence, method of diagnosis, most frequent imaging, indications for CT, and specific polic

144 frequency in unstressed animals, but is more frequent in animals that have experienced cellular stres

145 Mutations in PR-DUB components are frequent in cancer.

146 rs, strabismus, and fundus abnormalities are frequent in children with FASD and persist into early ad

147 e is bound by the DONSON protein and is more frequent in early S phase, in regions marked by euchroma

148 DNA repair GAs are relatively frequent in GBC and associated with coexisting actionabl

149 ercent completed a fellowship, with the most frequent in glaucoma (24%), cornea and external diseases

150 ate dehydrogenase (IDH) mutations are highly frequent in glioma, producing high levels of the oncomet

151 Hepatic steatosis was significantly more frequent in HH.

152 IEAT is frequent in high-risk patients with FN and BSI, despite

153 loidy variations such as genome doubling are frequent in human tumors and have been associated with g

154 s lowest and subthreshold parkinsonism least frequent in individuals with the Prevotella-enriched ent

155 Electrographic seizures are frequent in lobar intraparenchymal hemorrhage, occurring

156 Notably, ARID2 mutations are more frequent in melanoma than PBRM1 mutations.

157 to targeted therapies were numerically more frequent in NCI-MATCH than TCGA tumors, but not markedly

158 nd ethnicity/race (P < 0.001), with PCG more frequent in nonwhite patients, glaucoma associated with

159 nt was similar with BE and egg OIT, but more frequent in participants who are BE-reactive.

160 etween PVs and other adjacent structures are frequent in patient with atrial fibrillation (prevalence

161 d elevation of liver-enzyme levels were more frequent in patients receiving hydroxychloroquine, alone

162 od outcome, whereas TP53 mutations were more frequent in patients with poor outcomes.

163 nditions-termed here as Neuro-COVID-are more frequent in patients with severe COVID-19.

164 ARID1A, AHR, and SMARCB1 mutations were more frequent in PD.

165 Contralateral RD was more frequent in pseudophakic than phakic RD eyes (P < .0001)

166 ive impact of positively charged amino acids frequent in ribosomal proteins on ribosome progression.

167 oma associated with acquired conditions more frequent in South Asian patients, and glaucoma after cat

168 However, thrombosis remained frequent in spite of IMWG-guided thromboprophylaxis, sug

169 NMDAR IgGs were not more frequent in subjects who later became psychotic than tho

170 Culture contamination remained more frequent in the control vs diversion group (17/312 [5%]

171 Complications were more frequent in the elderly.

172 Treatment-emergent adverse events were most frequent in the highest dose group.

173 Hyperexcitable patterns were more frequent in the lobar group (44.3% vs 17.5%; p = 0.005).

174 e most common genetic diseases in the world, frequent in the Mediterranean basin.

175 verse skin reactions were significantly more frequent in the negative pressure group (7.0% vs 0.6%; d

176 tion, while NPC1 homozygous mutations may be frequent in the South Asian populations and warrants mor

177 sociated with yellow fever vaccine were less frequent in the TY014 group than in the placebo group.

178 on sexual orientation/sex identity was more frequent in the workplace than at academic conferences o

179 Seroconversion to HA was more frequent in those <20 years old (yo) for influenza A (se

180 HALT was more frequent in transcatheter versus surgical valves at 30 d

181 metastases (n = 20 out of 70, 29%), but less frequent in treated distant metastases (n = 9 out of 94,

182 These mutations were more frequent in tumor-type samples than in situ samples (P =

183 AST and ALT elevations are more frequent in US patients compared to Chinese patients.

184 kin care testing, to food safety to the most frequent in vitro diagnostic tests, partially conducted

185 ts, and glaucoma after cataract surgery more frequent in white patients.

186 The KLHL14 gene acquires frequent inactivating mutations in mature B cell maligna

187 ity at the attachment sites of tendons was a frequent incidental finding on knee MRI scans, with an i

188 ough the aneuploidy screening programme, are frequent incidental findings in pregnancy.

189 The most frequent indications for liver retransplantation were re

190 Psoriasis is a frequent, inflammatory skin disease characterized by ker

191 95% CI, 3.62-4.41]; P < .001), daily or more frequent injection (aHR, 1.45 [95% CI, 1.01-2.08]; P = .

192 nsulin, even with a much lower dose and less frequent injections, in non-obese diabetic mice with ins

193 We tested whether frequent insulin dose adjustments guided by an automated

194 low consumption of preserved foods, and the frequent intake of fresh fruits and vegetables), was ass

195 These shifts were often preceded by more frequent interactions between groups, but did not seem t

196 banded mongooses, a species characterized by frequent intergroup conflicts that have very different f

197 omosomal interactions and the unsurprisingly frequent intrachromosomal interactions along the diagona

198 During elective laparoscopic operations, frequent intraoperative errors and events, variation in

199 uctures with low-level copy-number gains and frequent inverted rearrangements.

200 Emerging studies highlight the frequent involvement of altered mammalian Switch/Sucrose

201 evasion and CNS neurovirulence in vivo by a frequent JCPyV-PML VP1 mutation.

202 ndent manner, but only when they experienced frequent jumping.

203 a significant increase in the probability of frequent khat use self-reported by men (AOR = 3.09, 95%

204 rce areas showed that Austfonna had the most frequent long-distance air flow, but showed lower amount

205 Cancer chemotherapy targeting frequent loss of heterozygosity events is an attractive

206 Frequent, low-cost, universal testing for severe acute r

207 The most frequent lymphoma subtypes were extranodal marginal zone

208 ncer (TNBC), which has poor prognosis due to frequent metastasis.

209 ctors SF3B1, SRSF2, and U2AF1 are subject to frequent missense mutations in clonal hematopoiesis and

210 est investigational therapies for moderately frequent molecular targets.

211 Rapid screening and frequent monitoring of immune responses are critical for

212 means of predicting progression to PDR, and frequent monitoring of IRMAs with SS OCTA may facilitate

213 of bipolar disorder is very narrow, and more frequent monitoring of sodium levels could avoid toxicit

214 ing the need for subcutaneous injections and frequent monitoring.

215 The most frequent MRI findings were signal abnormalities located

216 In LGMDR4 patients the most frequent mutation was c.341C>T.

217 The most frequent mutation was His to Tyr at amino acid 44; addit

218 The most frequent mutations in ctDNA of advanced HCC were TERT pr

219 LBCL-IRF4 had frequent mutations in IRF4 and NF-kappaB pathway genes (

220 The frequent mutations recovered recently from the pollen of

221 rimary age-related tauopathy) or moderate to frequent neuritic plaques (i.e. Alzheimer neuropathologi

222 ents and intraoperative rupture are the most frequent neurologic complications of intracranial aneury

223 neural dynamic range adaptation to the most frequent noise level and that auditory peripheral compre

224 L with predominant central-memory stages and frequent noncanonical patterns.

225 The prevalence of frequent nonmedical cannabis use did not differ by pain

226 The most frequent nonserious, device- and/or procedure-related ev

227 Deregulation of transcription factors is a frequent occurrence in CRC, and the accompanying drastic

228 eir article, Lax and colleagues reported the frequent occurrence of pulmonary thrombosis in a series

229 1.06-1.42) and extubation attempts were less frequent (odds ratio, 0.77; 95% CI, 0.65-0.93) after a t

230 We observed frequent on-target cytosine base edits at the BCL11A ery

231 the glucocorticoid group also displayed less frequent organ space surgical site infections (6.5% vs.

232 Fabry disease, the processes leading to the frequent outcome of ESKD are poorly understood.

233 iated neurocognitive disorders (HANDs) are a frequent outcome of HIV infection.

234 e was evidence of a significant reduction in frequent past-year alcohol intoxication self-reported by

235 outh Asian population and is one of the most frequent pathogenic variants in HCM in all populations;

236 Other frequent pathophysiologies were inflammation (n = 104, 3

237 ta properties beyond simple statistics, like frequent patterns, spatial changes, outliers, and spatio

238 l features is neurotropism, which results in frequent perineural invasion.

239 rly as 3 days after injury, characterized by frequent phagocytic cups, high phagosome content and CD6

240 rom their non-avian relatives, despite their frequent portrayal as an icon of adaptive radiations.

241 Osteosarcoma is the most frequent primary bone tumor with poor prognosis.

242 conditions) results from over irrigation or frequent rains.

243 orms that are poised to autonomously provide frequent, real-time, and accurate measures of biomarkers

244 Similarly, more frequent/recent vaccinations in children and younger pop

245 rbitol dehydrogenase gene (SORD) as the most frequent recessive form of hereditary neuropathy.

246 s containing SARS-CoV and SARS-CoV-2-undergo frequent recombination and exhibit spatially structured

247 d are coevolving) with the lineage, although frequent recombination and rearrangement events between

248 ineages, widespread geographical mixing, and frequent recombination.

249 Most frequent reductions were in the proportion of "high in"

250 urces required for prior authorizations, the frequent rejections, and the perception of being exclude

251 and endemic infectious diseases serves as a frequent reminder of the need to understand host-pathoge

252 Contrary to frequent reports in the literature, hydroxyl radical is

253 positive UAT result was associated with less frequent resistant organisms, but usually did not lead t

254 ildren and adults but in neonates results in frequent restenosis.

255 ce many clinicians did not train where CM is frequent, resulting in significant inertia to change.

256 Frequent role misidentification was associated with burn

257 US, HIV screening 3-monthly compared to less frequent screening will improve clinical outcomes and be

258 miRNA 3' ends are subject to frequent sequence modifications, which have been propose

259 d procedures, acute kidney injury (AKI) is a frequent, serious complication ranging from 10% to 30%.

260 Anaemia was the most frequent severe adverse event.

261 Droughts of the future are likely to be more frequent, severe, and longer lasting than they have been

262 ections that suggest SA will experience more frequent/severe droughts and rainfall events as a conseq

263 d because of their high production costs and frequent side effects.

264 Frequent, significant elevation in the gastro-esophageal

265 Bone is the most frequent site for metastasis for many cancers, notably f

266 , whereas predictability was lower with more frequent SOA deviants.

267 pediatric sequencing studies have identified frequent somatic Ras pathway alterations across a divers

268 n of deceased donor transplantation was less frequent, some restrictions to deceased donor kidney tra

269 neural dynamic range adaptation to the most frequent sound level.

270 s (n=10) under adrenergic stimulation showed frequent spontaneous development of early afterdepolariz

271 Frequent subclinical HSV DNA shedding was associated wit

272 e mixing was observed in two women with less frequent subclinical HSV DNA shedding.

273 bines an unsupervised learning strategy with frequent subgraph mining in order to detect conserved st

274 om species A (HRV A) and C (HRV C), the most frequent subtypes in the clinics of various pulmonary di

275 f the pulmonary artery occlusion pressure (a frequent surrogate of left atrial pressure) in this popu

276 with human survival post-term, and the most frequent survivable autosomal aneuploidy.

277 to identify other colchicine site binders, a frequent target of structurally diverse small molecules.

278 A damage response at telomeres, resulting in frequent telomere fusions.

279 betic ketoacidosis, which appears to be more frequent than initially described.

280 to emerge at much earlier ages and are more frequent than previously documented.

281 ith intra-island speciation found to be more frequent than previously thought.

282 on, we also found that transitions were more frequent than transversions in miRNAs.

283 ted coiling, thromboembolic events were more frequent than were intraoperative rupture.

284 environmental compartments is becoming more frequent, the whole-body burden (i.e., internal concentr

285 Furthermore, although saccades are more frequent, their dynamics are more sluggish (i.e. show lo

286 mong other organs of the patients and causes frequent thrombotic and neurological complications.

287 Frequent trade of rats between home-based ratteries cont

288 lly high slow waves, alpha/delta intrusions, frequent transitions, and muscle twitches are common tra

289 a single double-strand break (DSB) and more frequent translocations between two DSBs.

290 , mainly due to city population growth, more frequent travels and ecological changes.

291 n, topical application is preferable for the frequent treatment regimen that would be necessary for s

292 esh fruits/vegetables and wine were the most frequent triggers.

293 Although melanoma is the least frequent type of skin cancer, it accounts for the majori

294 Renal allograft rejection is more frequent under belatacept-based, compared with tacrolimu

295 e showed that cleaning was consistently more frequent when the presence of third-party species and cl

296 efinitions during 5-year follow-up were more frequent with an initial conservative strategy and assoc

297 lic events at 1 year were significantly less frequent with aspirin than with aspirin plus clopidogrel

298 Repeat revascularization was more frequent with FFR-guided PCI (24.9% versus 8.2%; hazard

299 eral neuropathy of grade 2 or above was less frequent with selinexor, bortezomib, and dexamethasone (

300 Severe bleeding was more frequent with ticagrelor.