ライフサイエンスコーパス: fruitful

1 e markers selected by several methods can be fruitful).

2 n further Balkanization is more likely to be fruitful.

3 here we believe further studies will be most fruitful.

4 sistance to increase the selectivity was not fruitful.

5 direction of pursuit that we feel should be fruitful.

6 sk group that does not need RT does not seem fruitful.

7 orts to inhibit their function have not been fruitful.

8 or of the cerebellum, have proven especially fruitful.

9 or neuroprotection in ALS are unlikely to be fruitful.

10 concerted case-finding approach may also be fruitful.

11 other areas in which these techniques may be fruitful.

12 icating vectors for other vaccines may prove fruitful.

13 sted by molecular modeling studies, were not fruitful.

14 ating that interdisciplinary research can be fruitful.

15 engineering with extrinsic dopants has been fruitful.

16 eural correlates of consciousness may not be fruitful.

17 ht where future investigations might be most fruitful.

18 and yet target-based discovery has not been fruitful.

19 lem during development has been particularly fruitful.

20 e should be refocussed so as to make it more fruitful.

21 R OF OVEREXPRESSION OF CONSTANS1, LEAFY, and FRUITFUL.

22 as where deeper connections are likely to be fruitful.

23 ce intracellular signaling events has proved fruitful, a great deal still remains to be elucidated re

24 OR OF OVEREXPRESSION OF CONSTANS1 (SOC1) and FRUITFUL act to promote flowering, whereas FLOWERING LOC

25 ting beta-adrenergic signaling have not been fruitful after decades of intensive research.

26 mulation models and argue that they may be a fruitful alternative to current approaches to the proble

27 ther social sciences to create a precise and fruitful alternative to traditional economic theories, w

28 tructure of full-length apoA-I have not been fruitful, although there have been successes with deleti

29 cells via needle-like appendages has opened fruitful and exciting areas of microbial pathogenesis re

30 The study of islands has proved particularly fruitful and has led to the theory that geographic area

31 omerically pure substituted indole has had a fruitful and important growth.

32 tion, orbit-use management is likely to be a fruitful and policy-relevant area for economic research.

33 For fruitful and rapid investigation of viral pathomechanism

34 asitologists and Bayesian statisticians as a fruitful and rewarding venture for advancing applied res

35 a proxy for transcriptome characteristics is fruitful and sufficient for a wide range of analyses.

36 First, it appears that studies are more fruitful and their results more replicable, broadly spea

37 But McCarty's scientific career was long and fruitful, and his contributions to science were vast.

38 We also highlight the importance of a fruitful antibody development pipeline to combat the pot

39 and these aetiological clues have inspired a fruitful application of the candidate gene association a

40 loyed in constructing such architectures for fruitful applications.

41 two structurally related receptors may be a fruitful approach for differential QSAR.

42 on of the latent senescence program may be a fruitful approach in cancer therapy.

43 A potentially more fruitful approach in future studies will be to test for

44 rizations of bicyclo[1.1.0]butanes provide a fruitful approach to cyclopropane-fused heterocycles.

45 m using animal and computational models is a fruitful approach to improve this promising therapy.

46 'brain-selective' LTCC ligands, could be one fruitful approach to innovative pharmacotherapy for bipo

47 A potentially fruitful approach to parsing this heterogeneity is to fo

48 heir unique N-terminal domains may provide a fruitful approach to prevent cognitive deficits in neuro

49 Thus, the modulation of sirtuins might be a fruitful approach to reversing the age-related metabolic

50 des, imaging membrane potential has become a fruitful approach to study neural circuits, especially i

51 One fruitful approach to the 'function' question is to contr

52 ng that structure-based drug design offers a fruitful approach to the development of selective inhibi

53 oma, and suggest that weight loss might be a fruitful approach to the prevention of these diseases.

54 ects of IFN and IFN gene therapy, might be a fruitful approach to the treatment of a variety of diffe

55 hem independently - will provide a much more fruitful approach to understanding mathematical abilitie

56 relative, Eutrema salsugineum, have proven a fruitful approach to understanding natural stress tolera

57 g that this strategy might be a particularly fruitful approach.

58 tal center make metalloprotein design a very fruitful area for the exploration and application of des

59 ng the asymmetry of the interaction can be a fruitful area of further research to better our understa

60 d-points are lacking, this is likely to be a fruitful area of further research.

61 Another potentially fruitful area of future research is the role of mesangia

62 athogenesis remain poorly understood and are fruitful areas for future research.

63 critically evaluates the data, and discusses fruitful areas for future research.

64 curs are not completely understood and offer fruitful areas for future research.

65 tors could be used to help identify the most fruitful areas for intervention, potentially improving r

66 ese findings, we identify knowledge gaps and fruitful areas for research that will further our unders

67 le data indicate that these pathways will be fruitful areas for study in the modification of renal di

68 emiological) research and theory and suggest fruitful areas for this synthesis.

69 e of homeostasis, promise to be particularly fruitful areas of future research.

70 surface mimics, such as silsesquioxane, is a fruitful arena for the discovery of new reactivity.

71 Our goal here is to contribute to a fruitful articulation of such proximate and ultimate exp

72 ery with fragment-based approaches have been fruitful, as a few bioactive ligands have been identifie

73 eting tumor suppressor genes has not been as fruitful, as many tumor suppressor genes are irreversibl

74 mechanisms that guide an animal to identify fruitful associations therefore have important survival

75 cussing how systems biology approaches are a fruitful avenue for addressing remaining challenges, suc

76 rmal response monitoring in ASD represents a fruitful avenue for further research.

77 ia, Toxoplasma and Sarcocystis, indicating a fruitful avenue for future research on how we have influ

78 at typical of healthy adolescents might be a fruitful avenue for future research.

79 ugs have recently emerged as an exciting and fruitful avenue for medicinal therapies.

80 anges over development in diverse cells is a fruitful avenue for schizophrenia research.

81 x biology of HIV-host interactions, the most fruitful avenue may be development of multivalent HIV im

82 consequently, inhibition of this enzyme is a fruitful avenue of investigation that may lead to the em

83 uited monocyte-derived cells may represent a fruitful avenue to ameliorate chronic inflammation in IB

84 haracterized microbial diversity and provide fruitful avenues for describing additional phylogenetic

85 We conclude by suggesting potentially fruitful avenues for future research.

86 he comparison between dreams and AAOM may be fruitful by suggesting new perspectives for the study of

87 ew insights that were only made possible and fruitful by these collaborations.

88 is has been made possible by an exciting and fruitful collaboration between clinicians, geneticists,

89 eristics of good modeling, presentation, and fruitful collaborations.

90 The time is ripe for a fruitful combination of these findings with two other lo

91 database are interrelated in ways suggesting fruitful combinations for document retrieval.

92 Fruitful comparison between this system and other stem c

93 Moreover, we establish a fruitful connection between tunable photon diffusion and

94 with theories that emphasize substantial and fruitful connections between patenting and prior scienti

95 Our data suggest the potential fruitful cooperation of anti-EGF receptor mAb and anti-H

96 They also establish fruitful correspondences with advanced topics in statist

97 A fruitful coupling of novel NMR techniques with segmental

98 nt concept of empathy and thereby for a more fruitful debate over the role of empathy in nursing.

99 ts suggest that the arylquinolines provide a fruitful departure point for the development of new anti

100 the reactivity of acrylates and styrenes, a fruitful development and formation of a novel five-membe

101 ist in the nanowires, with the appearance of fruitful dipole states (including those being purely pol

102 for relevant underlying processes could be a fruitful direction for building more general models of b

103 d other disorders of prematurity should be a fruitful direction for further investigation.

104 lpha in our simulations and should provide a fruitful direction for future studies.

105 the conditions that enable war or peace is a fruitful direction for the field to take.

106 rements, and computer scientists to pinpoint fruitful directions for algorithm improvement, we review

107 ssing in a flexible manner, and we highlight fruitful directions for further research.

108 l information, and indicate many potentially fruitful directions for new research.

109 silience-based framework can guide novel and fruitful directions for the field of psychiatric genomic

110 This surprising result suggests potentially fruitful directions for the improvement of computational

111 knowledge is summarized, and suggestions for fruitful directions of research are offered.

112 We are delighted by the broad, intense, and fruitful discussion in reaction to our target article.

113 sical Drosophila genetic system has provided fruitful disease models.

114 It therefore may be a fruitful domain for study of the general neural mechanis

115 ptor a more likely and worthwhile target for fruitful drug discovery.

116 This suggests PPAR gamma pathways may be a fruitful drug target in PD.

117 oteins involved in metal regulation might be fruitful drug targets.

118 h a dialog with ecology that can be mutually fruitful, e.g., by providing an explanation for how dive

119 We identify three "working edges" for fruitful elaboration of the Chunk-and-Pass proposal: (a)

120 Our results suggest that a potential fruitful empirical direction will be to understand how s

121 This perspective intends to cover my fruitful endeavor in the exploration of fluorine chemist

122 Fruitful endophenotype studies depend on the selection o

123 the Snail repressor blocks the formation of fruitful enhancer-promoter interactions when bound to a

124 These articles highlight the fruitful, essential, and increasingly prominent bridge t

125 s have greatly abetted the understanding and fruitful expansion of the theory of natural selection in

126 Our results suggest potentially fruitful extensions of both Baron-Cohen's theory and the

127 ng a range of subprocesses, providing a very fruitful field for the interaction of cognitive psycholo

128 nsiderable efforts have been devoted to this fruitful field.

129 Such a concept has already proven fruitful for a number of electronic applications in the

130 ease oxidative stress resistance could prove fruitful for crop improvement strategies.

131 key research areas that we feel are the most fruitful for further pursuit.

132 These findings suggest that it may be fruitful for future work to reconsider the value of mand

133 ted concept with other solvents would appear fruitful for future work.

134 nation (HR)-based methods, which have proved fruitful for gene targeting in non-plant systems, unsuit

135 explored areas of sequence space that may be fruitful for genome mining.

136 Analysis of single genomes has been fruitful for hypothesis generation such as the whole-gen

137 However, this process may not be as fruitful for ligands of nonenzymes.

138 mental drivers of social evolution may prove fruitful for predicting shifts in the costs and benefits

139 utational protocols are anticipated to prove fruitful for the characterization of a wide range of Ru-

140 at from whole genomes, this approach will be fruitful for the multitude of exomes that have been and

141 of vascular anomalies, has been particularly fruitful for the study of genetic regulation of angiogen

142 side chains was previously shown by us to be fruitful for this scaffold, since strong human immunodef

143 ar future, this hybrid system will likely be fruitful for understanding the genetics of reproductive

144 raits, closely related taxa are particularly fruitful for understanding the neurophysiological and ge

145 rtain solid-state NMR measurements have been fruitful; for example, some (13)C, (15)N, or (31)P reson

146 polynitrophenyl-1,2,5-oxadiazoles provides a fruitful foundation for the creation of the advanced hea

147 Our foray into rest was fruitful from both a scientific and methodological persp

148 This approach provides a fruitful functional linkage between structural bioinform

149 In closing, we discuss potentially fruitful future directions for the research field, inclu

150 Fruitful future directions may include investigating mor

151 ility that are observed and some potentially fruitful future directions to elucidate the architecture

152 psychiatric conditions and promises to yield fruitful GWAS targets in the years to come.

153 clusters and x-ray astronomy have a long and fruitful history.

154 in a consistent manner leads to potentially fruitful hypotheses for understanding the evolution of M

155 Two approaches have proven fruitful: (i) a divide-and-conquer strategy has provided

156 de association studies in ASD have also been fruitful, identifying 5 genome-wide significant loci thu

157 mely one that emphasizes 'edges' - may prove fruitful in addressing outstanding questions in network

158 g to a point where a reverse strategy may be fruitful in assigning the pathogenic effects of many dif

159 ctice of protein engineering is industrially fruitful in creating biocatalysts and therapeutic protei

160 ure-function relationship has already proved fruitful in designing biointerfaces.

161 nd/or investigation of family members can be fruitful in determining a cause and identifying at-risk

162 ding avirulence genes have been particularly fruitful in dissecting specific and common resistance si

163 These methods are already fruitful in exploring the interactions among cancer muta

164 oration with groups outside the EBI has been fruitful in extending PRIDE, including an approach to en

165 use of the techniques discussed could prove fruitful in generating a detailed map of cAMP signalosom

166 sing current methodology may not prove to be fruitful in generating definitive answers to shed light

167 genome-wide association studies may be more fruitful in identifying diet-gene interactions.

168 hological screens of pollen can be extremely fruitful in identifying previously unknown exine genes a

169 s of biologically active molecules have been fruitful in many bioinspired catalysis applications.

170 serve or increase brain GABA levels could be fruitful in remediating WM-related deficits associated w

171 developmental approaches that have been more fruitful in revealing perception-production associations

172 are hopeful that this new avenue will prove fruitful in significantly advancing our understanding of

173 ight areas where these would be particularly fruitful in the context of ecological energetics.

174 regulation of pancreatic function has proven fruitful in the determination of the molecular mechanism

175 fer processes, but also because it is really fruitful in the development of new analytical sensors.

176 This approach may be particularly fruitful in the medicinal leech because the neuronal bas

177 re studies and future directions that may be fruitful in the research on attention in Alzheimer's dis

178 -metal oxides have proved to be particularly fruitful in this regard, especially for those materials

179 covalent engagement to novel E3's has proven fruitful in TPD application.

180 approaches to block cytokine function may be fruitful in treating hyperinflammatory syndromes with le

181 h medication or brain stimulation, may prove fruitful in treating the symptoms of chronic dizzy patie

182 t areas for future research that might prove fruitful in ultimately providing new treatment options f

183 pportunities for RAS therapies and may prove fruitful in understanding basic cell biology.

184 ather to emphasize that this approach may be fruitful in understanding the podocyte and its unique pr

185 It would be fruitful--in addition to studying the ancient art of mem

186 community architecture in the brain provides fruitful information about the neural mechanisms of medi

187 s targeting the complement pathway may yield fruitful insights and/or advances in treatment options f

188 Therefore, this study not only provides fruitful insights into the design of more efficient comp

189 insects that adopted agriculture can provide fruitful insights into the evolution of complex human so

190 lgorithms with molecular networks has led to fruitful insights on disease genes.

191 ts and the visibility of Radiology through a fruitful interaction between radiologists and medical st

192 xistence of NVRS in monolayer h-BN indicates fruitful interactions between defects, metal ions and in

193 d to the targets of selection illustrate how fruitful interactions between theory and data can be.

194 These results reveal a fruitful interplay between algorithm design and active m

195 This Perspective surveys the recent fruitful intersection of chemical biology and remyelinat

196 If such an exercise is fruitful, it creates enormous opportunities to synthesiz

197 genetics tests targeting these genes will be fruitful, lead to the identification of natural sequence

198 Findings for specific chemicals may provide fruitful leads for further investigation.

199 While these approaches have been fruitful, lesions disrupt adjacent host tissue and fiber

200 However, one very fruitful line of analysis in the quest for such answers

201 firmed, these findings may provide a new and fruitful line of investigation into the molecular basis

202 ts within host cells has led to many new and fruitful lines of investigation into the biology of the

203 Looking forward, perhaps the most fruitful marriage of the advances in molecular genetics

204 molecular phylogenetic analyses may prove a fruitful means for furthering our understanding of biolo

205 otic prophase favor speciation by preventing fruitful meiosis between closely related organisms.

206 our current level of understanding, the most fruitful methods may incorporate both iterative selectio

207 Drosophila has proven a fruitful model for the investigation of evolutionarily c

208 e key features that make wine fermentation a fruitful model system for ecologists and evolutionary bi

209 s of the binding pocket, executing large and fruitful moves in chemical space with simple chemistry.

210 e modification is present; and (iv) can be a fruitful new angle for engineering in synthetic biology

211 cing suggests that that these regions may be fruitful new areas of study in understanding cardiac sod

212 Many potentially fruitful new avenues of cancer research are emerging tha

213 teraction between Prx1 and AR may serve as a fruitful new target in the management of prostate cancer

214 of three decades of investigation and recent fruitful observations have unveiled key elements of the

215 The past decade has been a fruitful one for geneticists involved in Parkinson's dis

216 t successful of these efforts have come from fruitful, ongoing collaborations among clinician investi

217 systems and integrative 'omics' represents a fruitful opportunity for molecular systems ecology.

218 microbial genome information has provided a fruitful opportunity for studying regulatory networks in

219 study of circadian rhythms is emerging as a fruitful opportunity for understanding cellular mechanis

220 down approaches, while also referring to the fruitful outcomes of recent genetic studies.

221 , two issues might hamper the achievement of fruitful outcomes.

222 ndeed, gold and fluorine truly formed a very fruitful partnership, and different types of reactivity

223 changes in pain are presented as providing a fruitful path for developing a core set of measures for

224 ith machine learning (ML) is one potentially fruitful path toward rapidly improving precision treatme

225 onal integration of nanomaterials could be a fruitful path towards building composites combining uniq

226 c suppression of charge recombination may be fruitful paths for the next generation of panchromatic o

227 genes in animal models of the disease mark a fruitful period in the field of type 1 diabetes genetics

228 Peirce can provide a fruitful perspective.

229 Furthermore, a fruitful phase diagram is obtained by controlling the di

230 f visual input and suggest that CNNs offer a fruitful platform for testing neuroscientific theories.

231 pramolecular copolymers in order to create a fruitful platform to design and investigate new multicom

232 Children born preterm provide a fruitful population for studying structure-function rela

233 he study of this phenotype has also provided fruitful population genetic insights into the interplay

234 and data sciences capability should herald a fruitful post-Modern Epidemiology world.

235 a first demonstration, we thus introduce the fruitful potential of spin manipulation by proximity eff

236 This method opens fruitful propects in various analytical fields such as m

237 A fruitful quantitative approach to understanding how the

238 This comprehensive review can serve as a fruitful reference source for peer researchers, thus pav

239 The most fruitful research strategy will be to examine the common

240 ceptual mechanistic framework will stimulate fruitful research that aims at unraveling the molecular

241 lysis, leaving untapped areas of potentially fruitful research.

242 One fruitful response to this noisiness has been to use stim

243 Fingerprinting models revealed fruitful results in classifying and quantifying CBEs in

244 known bvp4c method has been used to find the fruitful results.

245 A fruitful set of analytical methods (electrochemistry, ab

246 he Spemann organizer has proven to be a very fruitful source for gene discovery.

247 turally complex natural products have been a fruitful source for the discovery and development of new

248 nergy particle colliders are a traditionally fruitful source of exotic particle discoveries.

249 study suggests natural saponins may serve as fruitful sources for exploring/identifying potential the

250 d high-quality NMR experiments has reached a fruitful stage for characterizing structural ensembles o

251 These findings provide a fruitful starting point for improved models of social de

252 l, highly stable enzyme active sites will be fruitful starting points for investigations of non-natur

253 bacteria, and attempts to identify the most fruitful steps that can be taken to better understand ho

254 to search for disease genes still remains a fruitful strategy for complex diseases with a variety of

255 ng of TRPA1 genetic variants might provide a fruitful strategy for future development of pain treatme

256 hanisms of carotid body pathophysiology is a fruitful strategy for informing potential new treatment

257 geting EGFR expression and function may be a fruitful strategy for managing patients with uveal melan

258 modeling of metallo-enzyme active sites is a fruitful strategy for obtaining fundamental information

259 l to habitual to relapsing drug use may be a fruitful strategy for pinpointing which forms of drug-in

260 novel agonists, and how to predict the most fruitful strategy to apply.

261 ated efforts of multiple disciplines to be a fruitful strategy.

262 ation enhances the probability of success at fruitful synapsis.

263 on-specific genes and provides a potentially fruitful system for further studies of how migrating axo

264 Full understanding of these results paved a fruitful system to improve an applicable analytical proc

265 The small subunit may be a fruitful target for engineering improved Rubisco.

266 sts that this temperamental profile may be a fruitful target for high-risk genetic studies.

267 on suggests that the Nrf2-Prx1 axis may be a fruitful target for intervention with respect to inhibit

268 ria transmission suggests that AQP2 may be a fruitful target of antimalarial interventions.

269 n-coupled receptors (GPCRs) are frequent and fruitful targets for drug discovery and development, as

270 Phosphodiesterases are proving to be fruitful targets for drug discovery.

271 proteins and their associated genes as being fruitful targets for future studies of the molecular and

272 tification of phenotypes, which could become fruitful targets for genetic and imaging investigations

273 ses, and prostanoid receptors should provide fruitful targets for intervention in the pharmacological

274 hat either or both of these regions might be fruitful targets for neural stimulation studies (suppres

275 more groups are gaining an interest in this fruitful technique, new sample preparation techniques, s

276 The Drosophila hindgut is fruitful territory for investigation of events common to

277 lizing levels of Shank3 itself might be more fruitful than correcting pathways that function downstre

278 dental stops on the way to an ideal are more fruitful than the goal itself.

279 y to known human targets will likely be more fruitful than the traditional focus on unique bacterial

280 ver the past 10 years have been particularly fruitful, though key aspects about V- and Fe-nitrogenase

281 o know a priori which features would be most fruitful to analyze.

282 ion of multiple coinfecting viruses would be fruitful to assess whether a patient's disease course is

283 of universal quantum computing, it has been fruitful to consider various measurement based architect

284 n treating anxiety, it may therefore be more fruitful to encourage anxious individuals to integrate i

285 It may be more fruitful to examine the components of community-based se

286 cognitive benefits, we argue that it is more fruitful to examine the social-emotional effects of enga

287 tory to the field - that may be particularly fruitful to explore, with a particular focus on Brachypo

288 ng of a diverse set of GLP1R agonists proved fruitful to identify additional targeting ligands effica

289 It may be fruitful to identify populations that have escaped trade

290 focusing on regulatory variants may be more fruitful to locate/define future therapeutic targets.

291 It will be fruitful to merge three camps of gene fusion bioinformat

292 It may be fruitful to seek potential interactions between genetic

293 g aging and age-related diseases: it will be fruitful to use epigenetic tissue age as endophenotype i

294 It will likely be fruitful to wield this uncommon degree of knowledge to a

295 y (PT) might be one of the most powerful and fruitful tools for both physicists and chemists, which h

296 Fruitful use of these methods for short-term predictions

297 cer, infection, and autoimmunity have proven fruitful using the CD1d-binding glycolipid alpha-galacto

298 urzban et al.'s framework may be extended in fruitful ways by treating effort also as a cost input th

299 to draw the right conclusions that are more fruitful when compared to the original single data.

300 -based electrochemical (EC) sensors has been fruitful, yet there remains a need for more generalizabl