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1  the proposed computational approach will be fruitless.
2 ors of sexual differentiation: doublesex and fruitless.
3 ggering-competent H-stem constructs remained fruitless.
4 approaches to solving this conundrum will be fruitless.
5             The CL062 neurons do not express fruitless, a gene required for sexual dimorphism in flie
6 oexpressed in neurons of these sensilla with fruitless, a marker of sexual circuitry; IR52a is also e
7 r neurons that also sex-specifically express fruitless, a tra gene target controlling sexual behavior
8 wever, demonstrating that at a minimum, both fruitless and doublesex are involved in establishing sex
9 cuits expressing the sex-determination genes fruitless and doublesex drive quivering behavior.
10 authors identify the sex determination genes fruitless and doublesex, and a sex-specific P1-DN1 neuro
11  Two genes coding for transcription factors, fruitless and doublesex, have been suggested to play imp
12 itry established by the transcription factor Fruitless and triggered by sex-specific sensory cues.
13 ac,Tramtrack, Broad) domain proteins such as Fruitless are known to play key roles in the neural diff
14                                              Fruitless AS isoforms have been shown to influence male
15 Inspired by the fictional Baron Munchausen's fruitless attempt to pull himself up, it is demonstrated
16 We demonstrate that the transcription factor Fruitless(C) (Fru(C)) binds cis-regulatory elements of m
17 imorphic transcription factors doublesex and fruitless controls sexual differentiation and sexual beh
18 in certain fru-mutant males, indicating that fruitless controls the formation of these cells or 5-HT
19 ntramolecular Diels-Alder reactions remained fruitless, dialkylaluminum chloride led to the formation
20 tale-we wish to help other researchers avoid fruitless efforts to employ the many, seemingly promisin
21  these neurons have limited connections with fruitless expressing neurons that have been shown to be
22 uropeptide circuit largely overlaps with the fruitless-expressing neural circuit that governs most as
23 type II lineages that produce doublesex- and fruitless-expressing neurons and examined whether female
24    This activity involves sexually dimorphic fruitless-expressing neurons in the brain.
25  we demonstrate that knockdown of editing in fruitless-expressing neurons is sufficient to modify the
26                                  The loss of fruitless expression in these regions likely accounts fo
27 ecified by the male-specific products of the fruitless (fru(M)) gene; males without fru(M) do not cou
28                                              Fruitless (fru(M))-positive Or47b-expressing OSNs detect
29 orms of the neural sex determination factor, Fruitless (Fru(M)).
30  sex determination genes doublesex (dsx) and fruitless (fru) [1].
31  sex-determination genes doublesex (dsx) and fruitless (fru) [7-9].
32     We show that the sex determination genes fruitless (fru) and doublesex (dsx) both contribute to e
33  behavior in Drosophila are regulated by the Fruitless (Fru) and Doublesex (Dsx) transcription factor
34 coexpression of two sex-determination genes, fruitless (fru) and doublesex (dsx).
35  analysis of complementary DNAs specific for fruitless (fru) and Ods-site homeobox (OdsH) genes extra
36  role of the master courtship regulator gene fruitless (fru) and show that fru is necessary to ensure
37 ns that coexpress the sex-determination gene fruitless (fru) and the proprioceptive neuronal marker p
38  factors specific to each cluster identified fruitless (fru) as playing a role in stem cell regenerat
39                  In Drosophila melanogaster, fruitless (fru) encodes male-specific transcription fact
40 ne branch of this hierarchy is headed by the fruitless (fru) gene and functions in the central nervou
41 spliced transcription factors encoded by the fruitless (fru) gene are key determinants of sexual beha
42                Male-specific products of the fruitless (fru) gene control the development and functio
43              In Drosophila melanogaster, the fruitless (fru) gene controls essentially all aspects of
44  and behavioural studies have shown that the fruitless (fru) gene encodes a set of male-specific tran
45                               The Drosophila fruitless (fru) gene encodes a transcription factor that
46                                          The fruitless (fru) gene functions in Drosophila males to es
47 analyses of combinations of mutations of the fruitless (fru) gene have shown that male-specific isofo
48                                          The fruitless (fru) gene in Drosophila melanogaster is a mul
49 ex-specifically spliced transcription factor fruitless (fru) helps establish male courtship behaviors
50 ct regulatory targets of doublesex (dsx) and fruitless (fru) is crucial for an understanding of how t
51 cuitry in which the male-specific product of fruitless (fru) is produced, in a region that has been s
52 on mechanism for courtship behavior, whereas fruitless (fru) is required for enhancement of courtship
53 ale courtship behavior in the absence of the fruitless (fru) male protein.
54  females do not express transcripts from the fruitless (fru) P1 promoter.
55 tes the splicing of both doublesex (dsx) and fruitless (fru) pre-mRNAs but negatively affects the spl
56 eurons do not express the sexually dimorphic FRUITLESS (FRU) transcription factor, but form male-spec
57 nt of male-specific neurons that coexpressed fruitless (fru), a regulator of male sexual behavior.
58 one of the Drosophila sex determining genes, fruitless (fru), belongs to the neural circuit that gene
59 a melanogaster, the male-specific isoform of Fruitless (Fru), Fru(M), is a known master neuro-regulat
60 l differentiation genes, doublesex (dsx) and fruitless (fru), functioning with other regulatory facto
61 tities-defined by the sex determination gene fruitless (fru), neurotransmitters, monoamines, and tran
62 ship behavior in Drosophila are regulated by fruitless (fru), the first gene in a branch of the sex-d
63 nervous system, likely through regulation of fruitless (fru), to at least partially mediate the sexua
64 pressing the neural sex determination factor fruitless (fru), which have been implicated recently in
65 gaster males, when a subset of male-specific fruitless (fru)- and doublesex (dsx)-expressing neurons
66 -specific behavioral circuit identity marker fruitless (fru).
67 avior is regulated in large part by the gene fruitless (fru).
68  sex determination genes doublesex (dsx) and fruitless (fru).
69 in females by regulating splicing of dsx and fruitless (fru; another terminal gene within a branch of
70        Current models describe male-specific fruitless (fruM) as a genetic 'switch' regulating sexual
71                                Male-specific fruitless (fruM) is a major component inducing male beha
72 roductive tract labeled by both ppk-GAL4 and fruitless-GAL4 can sense sex peptide to control the indu
73 n c673a-Gal4-silenced flies, while silencing fruitless-Gal4 neurons alters only metabolism.
74 rform a similar function, the c673a-Gal4 and fruitless-Gal4 neurons.
75 ex peptide is generally believed to modulate fruitless-GAL4-expressing neurons in the central nervous
76                                          The fruitless gene in Drosophila produces male-specific prot
77                                          The fruitless gene is a major transcription factor with a wi
78                                          The fruitless gene is sex-specifically spliced and encodes a
79                                          The fruitless gene is well-known to play a key role in deter
80                                          The fruitless gene, immediate early genes in discrete seroto
81 ed Hsp22 gene and the male sex-determination fruitless gene.
82 ed by Fru(M), a male-specific isoform of the fruitless gene.
83 ng behavior via sex-specific splicing of the fruitless gene.
84  male courtship is controlled in part by the fruitless gene.
85 gion of chromosome 2 near the candidate gene fruitless, identifying these genes as suitable loci for
86 , the action of the male-specific isoform of fruitless in about 2000 neurons appears to be necessary
87            Here, we examine the structure of fruitless in multiple species of Drosophila, and determi
88 le duration and involve a new doublesex- and fruitless-independent branch of the sex differentiation
89               Furthermore, the male-specific Fruitless isoform (Fru(M)) is required for the sensory p
90 to female-specific splicing of doublesex and fruitless, leading to feminization of males both in morp
91                                  Remarkably, fruitless males also gain strong attraction to a live hu
92                                 We generated fruitless mutant mosquitoes and showed that males failed
93      To understand the molecular etiology of fruitless mutant phenotypes, we compared wild-type and m
94                                          The fruitless mutants fru3 and fru4 were assessed for sex-sp
95 e reduces male courtship and synergizes with fruitless mutations, suggesting that takeout plays a red
96                         Thus, in a subset of fruitless neurons, targets of the TIF and tra pathways a
97 r reproductive behaviors are orchestrated by fruitless neurons.
98 phila reproductive behaviors are directed by fruitless neurons.
99 lar, pC1d/e neurons and a specific subset of Fruitless+ neurons called aIPg.
100 eural network, including both Doublesex+ and Fruitless+ neurons.
101                                 Furthermore, fruitless, one of the major genes functioning downstream
102                   By manipulating either the fruitless or transformer genes in the brains of male or
103 ctor) and developmental (including Notch and Fruitless) pathways.
104 ily, ppk23 and ppk29, which are expressed in fruitless-positive neurons on the legs and are essential
105 in the Drosophila melanogaster doublesex and fruitless pre-mRNAs has been well studied and depends on
106 f sex-specific splice sites in doublesex and fruitless pre-mRNAs.
107 ry but this can be a laborious and sometimes fruitless process.
108 ns that expressed male-specific forms of the fruitless protein in the laterodorsal region of the brai
109 ubgroups of neurons expressing male forms of fruitless proteins (Fru(M)).
110                            The male-specific Fruitless proteins (FruM) act to establish the potential
111              The male-specific Doublesex and Fruitless proteins together activate Takeout expression,
112 ne function of ms-npf neurons is to modulate fruitless-regulated sexual behavior.
113 uits required to host-seek and that removing fruitless reveals this latent behavior in males.
114 egulation differs from that of doublesex and fruitless RNAs.
115                      The generalization that fruitless specified the development of the nervous syste
116  Importantly, one of these direct targets is fruitless, the master regulator of courtship.
117  behavior relies on a single splicing of the fruitless transcript, and on a specific olfactory-based
118           Regulating dendritic position, the fruitless transcription factor both connects the male-re
119 emonstrated that male-specific expression of Fruitless transcription factors (Fru(M) proteins) is nec
120 n-neural tissues culminated with claims that fruitless was both necessary and sufficient to establish
121 d for cryopreservation have, until now, been fruitless: we describe here a method for the cryopreserv
122                  In males that lack the gene fruitless, which controls persistent social behaviors in

 
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