ライフサイエンスコーパス: frustration

1 y that relies on the principle of 'energetic frustration'.

2 cannot be simultaneously satisfied (known as frustration).

3 ates of matter, enriched by ingredients like frustration.

4 d version of a webserver that measures local frustration.

5 ivid the origin of this principle of optimal frustration.

6 ractions in the protein and is also known as frustration.

7 g emergent charges arising from kagome Ising frustration.

8 state, while also reducing the LuFe2O4 spin frustration.

9 enes (TSGs) induce very different changes in frustration.

10 lume change upon spin transition and elastic frustration.

11 rvation rather than relief of the effects of frustration.

12 onal antiferromagnet, even in the absence of frustration.

13 es are more malleable and dominated by local frustration.

14 ate nor core etching, because of geometrical frustration.

15 hieved within in a close-packed layer due to frustration.

16 xhibiting interesting magnetism such as spin frustration.

17 structure-based model with minimal energetic frustration.

18 tic 'fingerprints' associated with geometric frustration.

19 egory of materials able to exhibit geometric frustration.

20 ins to separate cleanly because of geometric frustration.

21 udy conformational dynamics connected to the frustration.

22 ing" was positively related with experienced frustration.

23 m conformer-specific effects, such as steric frustration.

24 ould be elaborated to capture this source of frustration.

25 ability during attention orienting following frustration.

26 d is not delivered, this will be replaced by frustration.

27 an emotional basis, e.g. aggression based on frustration.

28 g attention orienting in the trial following frustration.

29 essure or magnetic field, which enhances the frustration.

30 rdered region, which modulates the degree of frustration.

31 t native-centric forces is conceptualized as frustration.

32 romagnetic interactions, can generate such a frustration.

33 e oxide slowly interact and develop magnetic frustration.

34 peratures, the scale of which may imply weak frustration.

35 magnetic exchange interaction induces a high frustration.

36 conformation at endosomal pH could relax the frustration, allowing histidine protonation and facilita

37 This frustration, along with the multipartite nature of the b

38 Our results indicate that changes in local frustration also affect partitioning in vivo between spo

39 t a particular patient's disease all lead to frustration among patients, family and the physicians.

40 ars to be mediated by macromolecular packing frustration, an entropic contribution to the interpartic

41 Atomistic frustration analysis provides a route for screening for

42 ic resolution, it becomes possible to extend frustration analysis to protein-ligand complexes.

43 s are delicately balanced, leading to strong frustration and a near degeneracy of different ground st

44 Managing the condition was associated with frustration and anxiety, in part due to uncertainty rega

45 Frustration and deformation occur in arrays of polymers

46 o investigate many-body phenomena related to frustration and disorder in a material that could be tai

47 but a spin Jahn-Teller distortion lifts the frustration and enables the magnetic ordering to lock in

48 a source of social conflict that can lead to frustration and even bloodshed.

49 healthy comparison groups reported increased frustration and exhibited decreased ability to shift spa

50 nker includes therefore sites of R:C complex frustration and frustration-relieving mutations enhance

51 This engenders feelings of frustration and futility in both patients and the dermat

52 lement in the system, finding a link between frustration and ground-state entanglement.

53 This leads to frustration and highly degenerate ground states the natu

54 of knots via the interplay of the geometric frustration and intrinsic chirality.

55 ttle is known about the relationship between frustration and its underlying sequence determinants.

56 hus allowing versatile tuning of geometrical frustration and manipulation of ground state configurati

57 , and analysis of the coupling between local frustration and metal binding interactions for a glycine

58 These results highlight the overlap between frustration and pain, and suggest that genetic variation

59 ghlighting the deep connection between phase frustration and pattern formation, and perspectives on t

60 e lattice distortions that partially relieve frustration and produce ground states with zigzagging st

61 Geometric frustration and quantum fluctuations can happen beyond m

62 Geometric frustration and quantum fluctuations may prohibit the fo

63 ty of the H-bond network in cellulose due to frustration and redundancy in the placement of H-bonds.

64 does not exist due to a lack of geometrical frustration and sheds light on the nature of disorder.

65 cal coupling parameters reflect this lack of frustration and strongly distinguish like-charge electro

66 ry of the self-assembled structures leads to frustration and the assembly of unique materials.

67 lay between membrane elasticity, geometrical frustration, and achiral symmetry breaking can be used t

68 can lead to delays in patient care, provider frustration, and patient anxiety.

69 ion of their full impact, causing confusion, frustration, and possibly patient harm.

70 ent electronic/magnetic structures caused by frustration, and the findings lead us to propose a class

71 inhibitors illustrates the unpredictability, frustrations, and potential rewards of drug development

72 al stresses-an intrinsic signature of glassy frustration-anharmonicity and low-frequency vibrational

73 Frustration appears to reduce attention flexibility, par

74 magnetism, systems incorporating geometrical frustration are fascinating, as their behavior is not on

75 , at least two very different definitions of frustration are used.

76 rototypical system in three dimensions where frustration arises from competing interactions rather th

77 e results enabled us to identify the elastic frustration as the fundamental mechanism at the origin o

78 in n-butanol is in fact caused by geometric frustration associated with an isotropic to rippled lame

79 iently to quantify and localize biomolecular frustration at atomic resolution by examining the statis

80 nd spin texture associated with the magnetic frustration at the bar vertices.

81 the significantly reduced curvature-induced frustration at the convex interfaces of the normal gyroi

82 We expect this frustration-based model of allostery will prove to be ge

83 nvolvement of this pathway helps explain the frustration behind the failure at targeting either IFN-a

84 The concept of frustration between competing geometrical or bonding mot

85 rged species as resulting from a topological frustration between local homonuclear and long-ranged he

86 complex soft-matter self-assembly, by using frustration between space filling and the entropic penal

87 ed states of matter that emerge from quantum frustration between spin and orbital degrees of freedom.

88 This process suggests frustration between two partially ordered forms of the p

89 longer quarantine duration, infection fears, frustration, boredom, inadequate supplies, inadequate in

90 cally ordered phase develops due to magnetic frustration, but a spin Jahn-Teller distortion lifts the

91 We control the amount of frustration by continuously tuning the range of interact

92 ificial ices enable the study of geometrical frustration by design and through direct observation.

93 ident lattice, but also demonstrate how this frustration-by-design concept can deliver magnetically f

94 a two-dimensional lattice geometry where the frustration can be controlled by tuning the unit cell pa

95 Here, we show that geometric frustration can be exploited as a vehicle for conductivi

96 viors illustrates that the degree of elastic frustration can be manipulated by molecular guests, whic

97 In the case of quantum networks, frustration can lead to massively entangled ground state

98 raph theory, we demonstrate that topological frustrations can be avoided while simultaneously preserv

99 ons, folding routes experiencing topological frustrations can be either enhanced or relieved.

100 Such a conflict, or frustration, can result in the formation of partially mi

101 negative feedback received in the context of frustration, children with severe, chronic irritability

102 perties show evidence for increased magnetic frustration compared to the parent compound NaCrS(2).

103 ral response to positive feedback during the frustration condition did not differ between groups.

104 bility to shift spatial attention during the frustration condition relative to the nonfrustration con

105 During the frustration condition, participants in the severe mood d

106 ulating synthesis", we reveal that geometric frustration confers, on a system at ambient temperature,

107 In oxidized nDsbD, local frustration disrupts the packing of the protective cap-l

108 t massively destabilizes the complex through frustration, does not participate in specificity directl

109 The frustration-driven nature of the flat band is directly c

110 Moreover, the level of frustration due to evolutionary conflict dictates the de

111 d with the effects of economic and political frustrations during times of rapid social change.

112 interactions and their abundances due to a "frustration" effect: Strengthening of functional interac

113 In this paper, we observe frustration effects in quasicrystal artificial spin ice

114 Kondo, crystal electric field, and magnetic frustration effects may be present, resulting in low tem

115 ce of soft elastic modes have little elastic frustration: Energy is insensitive to most directions in

116 d active site geometry, with Lewis acid/base frustration enforced by the protein secondary structure.

117 rromagnetic net structure, allowing study of frustration-enhanced magnetocaloric effects in a finite

118 tacts, a conflict we term electronic packing frustration (EPF).

119 ble crystallographic signatures of geometric frustration: excess volume and correlated "snake-like" i

120 redictions based on the principle of minimum frustration, fast-folding sequences match their Go-like

121 sults demonstrate the importance of chemical frustration for understanding biomolecular energy landsc

122 cular importance for metallic systems, where frustration forms the basis for the design of metallic g

123 hich a local Hamiltonian is guaranteed to be frustration-free by lifting Shearer's theorem from class

124 Here we introduce a continuous family of frustration-free Hamiltonians with exactly solvable grou

125 Frustration-free Hamiltonians, in turn, play a central r

126 ero energy, i.e., whether its Hamiltonian is frustration-free.

127 shows that the switch is driven by magnetic frustration from antiferromagnetic Mn(2+) spin ordering

128 Frustration from strong interdomain interactions can mak

129 e structure, this study introduces "chemical frustration" from deprotonation and misligation that giv

130 s to frustrating stimuli, the authors used a frustration functional MRI (fMRI) paradigm to examine as

131 After two decades of frustration, genetic studies of schizophrenia have enter

132 Geometric frustration gives rise to new fundamental phenomena and

133 The magnetic frustration has a clear in-plane (ab) magnetic anisotrop

134 The frustration has been ascribed to premature docking of th

135 Although geometric frustration has been particularly well studied in magnet

136 Mechanisms related to geometric frustration have been proposed to understand the origins

137 rimental support to the principle of minimal frustration hypothesis.

138 ands 1 and 4), which cause early topological frustration (i.e., misfolding) in the folding landscape.

139 nar dipole moment, is receptive to geometric frustration if the columns aggregate in a hexagonal rod

140 with the proximal glutamate; this structural frustration implies a "rack" mechanism for the 290 mV (v

141 nduced anisotropy has the ability to relieve frustration in 5d(2) systems relative to their 5d(3) cou

142 nal MRI study to examine neural responses to frustration in children with severe mood dysregulation.

143 tigate numerous phenomena of the geometrical frustration in condensed matter.

144 ding the effect of curvature and topological frustration in crystals yields insights into the fragili

145 To understand the effects of such local frustration in dictating the energy landscape of protein

146 egion recently identified as contributing to frustration in folding acts as a regulatory hinge loop t

147 Frustration in folding, i.e., backtracking in native con

148 requirement for function can lead to kinetic frustration in folding.

149 f enquiry into the importance of the role of frustration in highly correlated electron materials.

150 electron-hole matching approach to inducing frustration in intermetallic systems.

151 Geometric spin frustration in low-dimensional materials, such as the tw

152 Energetic frustration in protein folding is minimized by evolution

153 Much of the physical basis of minimal frustration in protein folding thus remains to be elucid

154 erged as model systems for studying magnetic frustration in recent years.

155 sensitive Go-model simulations conclude that frustration in the folding in Spo0F, corresponding to th

156 roles in biasing the early events leading to frustration in the folding of CheY.

157 We show that frustration in the heterodimer interface gives the heter

158 gnificantly different from bulk water due to frustration in the hydrogen-bond network induced by inte

159 is a property of the core, and suggest that frustration in the landscape of the slow-folding spectri

160 encoded in the molecular structure, staging frustration in the metallic state is challenging due to

161 in the EIS while other residues experiencing frustration in the native state are in structured region

162 (KIS), with this difference being related to frustration in the structure of Im7.

163 Frustration in this landscape can arise from the competi

164 lly suited to the exploration of geometrical frustration in three dimensions, and their rich phenomen

165 onalized on the basis of geometrical packing frustration in which the channels occupy defect sites th

166 The term "frustration" in the context of magnetism was originally

167 have investigated the conditions under which frustration increases the folding rate.

168 We also present evidence that geometric frustration-induced conductivity is a general phenomenon

169 eometrical Hall effect at T<1.2 K due to its frustration-induced magnetic order.

170 transverse polarized state, and observe that frustration induces extra degeneracy.

171 and ascribe their stability to a geometrical frustration inherently present in chiral colloidal membr

172 coexistence of ferromagnetism and geometric frustration intrinsic to the kagome network of magnetic

173 Geometric frustration is a broad phenomenon that results from an i

174 Frustration is a useful concept for analyzing proteins'

175 Frustration is detected in H1-H2 packing in that a nonna

176 of major enzyme classes, showing that local frustration is evolutionarily more conserved than the pr

177 Although a significant degree of frustration is expected, we find that Sr2MgOsO6 orders i

178 This frustration is harnessed by guest exchange to yield a ve

179 ant designed computationally to have reduced frustration is indeed less GroEL-dependent.

180 me, and that a sufficient level of energetic frustration is needed for fast-translating codons to be

181 ems that embody the statistical mechanics of frustration is now possible using nanotechnology.

182 Whilst magnetic frustration is observed in numerous electrically insulat

183 Experiment indicates that frustration is often minimal in evolved biological syste

184 Computational analysis reveals how this frustration is relieved in the tricyclic peroxide produc

185 An anticipated consequence of this frustration is the emergence of chemical pressures (CPs)

186 Frustration is thought to underpin biomolecular recognit

187 del landscape (in particular, the feature of frustration) is consistent with detailed simulations eve

188 rstanding the emotional reaction to loss, or frustration, is a critical problem for the field of ment

189 ics by exploiting a combination of geometric frustration, lattice distortions and epitaxial engineeri

190 electrostatics seems to remove some of that frustration, leading to enhanced formation of native-lik

191 In spin ice, magnetic frustration leads to highly degenerate yet locally const

192 ttice of triangular motif, the phenomenon of frustration leads to numerous energetically equivalent g

193 Following frustration, levels of irritability correlated with acti

194 An intermediate level of frustration maximizes the chance of evolving bnAbs.

195 t an addition of a small amount of energetic frustration may enhance folding speed for certain protei

196 udy leads strong support for the geometrical frustration mechanism for dynamic arrest in both thermal

197 cular, those associated with TSGs change the frustration more in the core than the surface (by introd

198 ms obtaining a referral (23% [18%-29%]), and frustration obtaining health care services (26% [23%-28%

199 accessing specialty care (29% [26%-33%]) and frustration obtaining health care services (36% [32%-41%

200 Geometrical frustration occurs when entities in a system, subject to

201 In assemblies, the geometric frustration of a locally preferred packing motif leads t

202 ense of metal-binding affinity, and that the frustration of a residue is directly related to its role

203 elix and discuss the apparent conformational frustration of AMCP-containing oligomers.

204 The sign of EB is related to the frustration of antiferromagnetic coupling between the fe

205 allows a complete relaxation of the inherent frustration of antiferromagnetism on a hexagonal close-p

206 By examining the curvature frustration of both high and low curvature, the transfer

207 This frustration of crystallinity reveals that La(3+) disrupt

208 Frustration of crystallisation by locally favoured struc

209 We find that geometric frustration of dimer rotation by interactions yields spa

210 type of basis cell can reduce or remove the frustration of EET rates across the photosynthetic netwo

211 of apomyoglobin contributes to the energetic frustration of folding by preventing docking and stabili

212 ansformations are fueled by stereoelectronic frustration of H(2)O(2), the parent peroxide, where the

213 Frustration of inter-filament spacing leads to optimal s

214 monoclinic I2/m symmetry, which reduces the frustration of the face centered cubic lattice of Os(VI)

215 n, the magnets are locally unfrustrated, but frustration of the lattice persists due to its topology.

216 Geometrical frustration of the molecule-cage interaction in FAPbI3 p

217 erest due to their potential for geometrical frustration of the ordering of magnetic moments or orbit

218 We find that frustration of the otherwise dominant Fe stripe and V Ne

219 due to superexchange interaction, the strong frustration of the phase string signs on the kinetic ene

220 behaviour is due in part to the geometrical frustration of the weak intermolecular hydrogen bonds an

221 g rates may be correlated with the degree of frustration of their respective energy landscapes.

222 Steric frustration of this binding was seen with Mes3P, and yet

223 effects of emotional labour (e.g. conflicts, frustrations) of patient flow processes on nurses are si

224 Sites of high local frustration often correlate with functional regions such

225 der (ADHD) and has been frequently linked to frustration or the unsatisfied anticipation of reward.

226 Frustration, or the competition between interacting comp

227 We survey the local energetic frustration patterns of all protein enzymes with known s

228 ce and structure, while displaying different frustration patterns.

229 e pointed to the opioid system as a nexus of frustration, physical pain, and substance abuse.

230 Geometrical frustration plays a crucial role in this process, and ac

231 Feelings of frustration, powerlessness and guilt were common and deb

232 The principle of minimal frustration predicts that the unfolded ensemble is biase

233 at localizing and quantifying the energetic frustration present in protein molecules.

234 This frustration produces a non-collinear spin state even wit

235 rkflow on the Protein Databank, we find that frustration produces many immediately intuitive results:

236 e, we describe a workflow in which localized frustration, quantifying unfavorable local interactions,

237 Geometrical frustration, quantum fluctuations, and low dimensionalit

238 ns can be improved and patient and clinician frustration reduced while acknowledging the financial re

239 As a consequence, the optimum frustration regime for protein folding can be predicted

240 erefore sites of R:C complex frustration and frustration-relieving mutations enhance the kinase inhib

241 Although many frustrations remain with physicians' ability to measure

242 A review on geometric frustration remarks that classical crystallography is in

243 lectric hexaferrite BaFe12O19 with geometric frustration represents a promising candidate for the pro

244 med to induce both positive anticipation and frustration, respectively, within a single controlled ex

245 Frustration responses can occur in superficially similar

246 This frustration results in a two-dimensional periodic honeyc

247 fferentiating neural activity in response to frustration (rigged feedback) from activity during atten

248 Here, we demonstrate that geometric frustration selects the equilibrium morphology of cohesi

249 to examine the relationship between magnetic frustration, short-range magnetic order and Fermi surfac

250 states according to the principle of minimal frustration, so that a sequence can spontaneously fold,

251 t signals, this repressilator can generate a frustration state with large variations (fluctuations or

252 Frustration stress also increased Fos (a neuronal activi

253 This "frustration stress" manipulation also activates the hypo

254 the sight of the palatable food for 15 min (frustration stress) before assessing food consumption fo

255 ceptor antagonist D-Phe-CRF(12-41) decreased frustration stress-induced binge eating in rats with a h

256 mpact on patients and caregivers, leading to frustration, stress and isolation.

257 After years of frustration, success in identifying disease-associated D

258 en functional fold, the principle of minimal frustration suggests that, independent of sequence, all

259 The frustration suppresses conventional antiferroelectric or

260 in face emotion labeling and experience more frustration than do normally developing children, the br

261 ed SNVs create stronger changes in localized frustration than non-disease related variants, and rare

262 periments also identify regions of energetic frustration that "crack" during unfolding and impede the

263 demonstrate a consequence of this geometric frustration that leads to a new design principle for the

264 introduce sizeable topological or energetic frustration that needs to be overcome.

265 ral state is stabilized without any apparent frustration, the common avenue to generate spiral arrang

266 To test the interlayer frustration, the crucial component of the PDW picture, w

267 Local structural frustration, the existence of mutually exclusive competi

268 Elastic frustration, the inability to simultaneously minimize co

269 us, according to the strength of the elastic frustration, the system may undergo first-order transiti

270 from the analysis: the journey from fear to frustration; the need to maintain a healthy identity; co

271 Primarily considered a medium of geometric frustration, there has been a growing recognition of the

272 es the dynamic processes associated with the frustration to be dampened.

273 s disorder tuned SIT differs from the common frustration tuned SIT that also occurs in magnetic field

274 rial oxidoreductase DsbD (nDsbD), introduces frustration ultimately influencing protein function.

275 In particular, we imposed geometric frustration upon a prototypical system, CaF2, by ball mi

276 hange in free energy and the local energetic frustration upon binding, we engineered a single-point m

277 Nonproductive frustration was attributable to competition for van der

278 Conversely, mutations at positions with low frustration were found to correlate with increased GroEL

279 However, these effects of frustration were more marked in the severe mood dysregul

280 roles of the subdomains and ILV clusters in frustration were tested by altering the sequence connect

281 s a materials-by-design approach to studying frustration, where lithographically patterned bar magnet

282 applied to the s = 1/2 Heisenberg star with frustration, where the quantum character of the environm

283 ut unverified source for GroEL dependence is frustration, wherein not all interactions in the native

284 evolving following the principle of minimal frustration, which allows proteins to rapidly fold to th

285 rating a key phenomenon known as topological frustration, which leads to localized non-bonding states

286 of the Cu atoms to icosahedra prevents this frustration while nucleating the formation of Bergman cl

287 Frustration with donning/doffing was especially apparent

288 However, clinicians indicate frustration with the lack of guidance provided by the US

289 compound exhibits a high degree of magnetic frustration, with significant antiferromagnetic interact

290 mong critical care professionals, leading to frustration, withdrawal from patient care, and job aband

291 ings lead us to propose a classification for frustration within molecular magnets that encompasses an

292 a pairwise interactions, the latter reflects frustration within the landscape for local conformationa

293 ce of a topological defect produces extended frustration within the system caused by a domain wall wi

294 ntary guests to eliminate the "electrostatic frustration" within the host and turn on the intrahost i

295 nal vision, bothered by eyes/vision, social, frustration/worry (10 items each).

296 re lower for residual amblyopia on the Child Frustration/worry domain (P = .03), on 4 of 5 Proxy doma

297 vision, bothered by eyes/vision, social, and frustration/worry domains).

298 nal vision, bothered by eyes/vision, social, frustration/worry, and eye care.

299 nal vision, bothered by eyes/vision, social, frustration/worry, eye care (total 39 items), as did the

300 vision, bothered by eyes/vision, social, and frustration/worry.