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1 complex extracellular matrix polysaccharide fucoidan.
2 f four monoclonal antibodies (mAb) targeting fucoidan.
3 ed assay for detection and quantification of fucoidan.
4 ted polysaccharide showed characteristics of fucoidan.
5 evealing CLEC-2 as a physiological target of fucoidan.
6 luding f-Alb, maleylated bovine albumin, and fucoidan.
7 tes is inhibited in the presence of EDTA and fucoidan.
8 the presence of EDTA and the polysaccharide fucoidan.
9 oidan (Fysk) and those of previously studied fucoidans.
10 chinery for the degradation of six different fucoidans.
11 maximum sulphated fucoidan content (41.38 g fucoidan/100 g extract) was obtained at 160 degrees C, w
12 In particular, administration of 2 doses of fucoidan (25 mg/kg) over 6 hours produces profound mobil
13 gregation and Syk phosphorylation induced by fucoidan, a CLEC-2 agonist, were unaffected in RhoG-defi
23 itive reconstitution experiments reveal that fucoidan also elicits long-term (more than 6 months) rep
31 f soluble glycoconjugates, of which heparin, fucoidan, and dextran sulfate were the most effective.
32 h as different glycosaminoglycans, alginate, fucoidan, and glycans were profiled by this comprehensiv
33 ulfate 500K, dextran sulfate 5K, sulfatides, fucoidan, and heparin but not by chondroitin sulfate A.
34 sigargin and the scavenger receptor A ligand fucoidan, and restoring iPLA(2)betaexpression with recom
35 ies to confirm suggested structures of algal fucoidans, and (iii) developing a fucoidan microarray.
36 at of other polysaccharides, suggesting that fucoidans are more recalcitrant and may sequester carbon
37 e complexity of the pathways underscores why fucoidans are probably recalcitrant and more slowly degr
38 fated polysaccharides from brown algae - the fucoidans - are known to be a topic of numerous studies,
41 ger receptor inhibitors, dextran sulfate and fucoidan, attenuated monocyte migration toward stressed
42 nd crosslinking methods, then highlights the fucoidan attributes, fabrication of fucoidan-based elect
43 ghts the fucoidan attributes, fabrication of fucoidan-based electrospun nanofibers, their properties
45 This study investigated the multiproduct (fucoidans, beta-glucans, proteins, carotenoids, fatty ac
46 RNA for macrophage scavenger receptor A, and fucoidan blocking of macrophage scavenger receptors inhi
47 sulfated polysaccharides dextran sulfate and fucoidan, but not others, reduce endothelial cell-surfac
51 l permeability of high molecular weight (Mw) fucoidan can limit its effectiveness in drug action, whi
55 In addition, it binds the polysaccharide fucoidan, consistent with its C-type lectin homology and
56 showed that Japanese Cladosiphon okamuranus fucoidan contained 70.13 +/- 0.22 wt% fucose and 15.16 +
60 tion on reducing the molecular weight of the fucoidan extracts and examine the cytotoxic effect of di
62 y was to elucidate the chemical structure of fucoidan from Cladosiphon okamuranus harvested in Japan.
65 ry three fucose units, i.e. the structure of fucoidan from Japanese Cladosiphon okamuranus is [->3)-a
69 vidence for further exploring the use of the fucoidans from S. cichorioides, F. evanescens, and U. pi
70 by chronic hypoxia (35 d) were given either fucoidan (from Fucus vesiculosus) or anti-P-selectin ant
71 ifferent than those of commercial food grade fucoidan (Fysk) and those of previously studied fucoidan
72 arides by (i) characterizing two endo-acting fucoidan glycoside hydrolases (GH107), (ii) utilizing th
78 apidly and dramatically after treatment with fucoidan in monkeys and in mice, coinciding with decreas
80 c release, and we find that thapsigargin and fucoidan induce mitochondrial phospholipid loss and cyto
86 ffect on platelets and the receptor by which fucoidan induces cellular processes has not been elucida
89 Sulfated polysaccharides (e.g. heparin and fucoidan) inhibited binding of soluble DC-HIL-Fc and adh
96 Due to its persistence in the environment, fucoidan is potentially a pathway for marine carbon sequ
99 r, carrageenan, porphyran), brown (alginate, fucoidan, laminarin, mannitol), and green (ulvan) seawee
100 lose, chitosan, pectin, starch, carrageenan, fucoidan, mannan, glucomannan, and arabic gum) and prote
102 ns (e.g. fucosylated chondroitin sulfate and fucoidan), nothing is known about their protein-linked g
104 e, evidence is provided that the addition of fucoidan or dextran sulfate to unfractionated plasma res
105 t treatment with the sulfated polysaccharide fucoidan or the structurally similar dextran sulfate inc
110 l inhibitors of class A scavenger receptors (fucoidan, polyinosinic acid, and dextran sulfate) reveal
111 asis for molecular level investigations into fucoidan's roles in medicine and carbon sequestration.
112 imum estimation by acid hydrolysis indicated fucoidan secretion at a rate of 28 to 40 mg C kg(-1) h(-
114 nly of carbon, oxygen, hydrogen, and sulfur, fucoidan secretion does not consume nutrients enabling c
117 the antioxidant butylated hydroxytoluene nor fucoidan, suggesting that lipid accumulation did not inv
118 haM-/- HPCs were preferentially mobilized by fucoidan, suggesting that the enhanced mobilization is c
120 ration of fucose, related to the presence of fucoidans that have important biological functions.
121 trations of a highly charged polysaccharide, fucoidan, the microscale ordering of Fmoc-FRGDF peptide
122 to 1 Gt of biomass annually, yet the fate of fucoidan-their major cell wall polysaccharide-remains po
123 enon we found that BM myeloid cells bound to fucoidan through the integrin alphaMbeta2 (macrophage an
124 and the binding was inhibited by heparin and fucoidan, thus supporting the hypothesis that P97 was ac
125 erpretation of results from studies that use fucoidan to "block" either scavenger receptors or L- or
127 ng of acetylated low density lipoprotein and fucoidan to MSR-A in human THP-1 macrophages triggered t
128 kin-8, MCP1, or MMP9 were also present after fucoidan treatment, studies in gene-ablated mice (GCSFR(
132 in FcRgamma-chain null mice, indicating that fucoidan was not acting primarily through GPVI receptor.
137 utination activity (i.e. dextran sulfate and fucoidan) whereas high concentrations inhibited parasite
138 reated with anti-P-selectin antibody or with fucoidan (which inhibits P- and L-selectin function).
139 x, branched and highly sulfated structure of fucoidans, which also varies among species of brown alga
141 that Fsar has fundamental characteristics of fucoidan with different structural conformation i.e. var
142 om, Thalassiosira weissflogii, synthesizes a fucoidan with structural homology to those found in brow