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1  complex extracellular matrix polysaccharide fucoidan.
2 f four monoclonal antibodies (mAb) targeting fucoidan.
3 ed assay for detection and quantification of fucoidan.
4 ted polysaccharide showed characteristics of fucoidan.
5 evealing CLEC-2 as a physiological target of fucoidan.
6 luding f-Alb, maleylated bovine albumin, and fucoidan.
7 tes is inhibited in the presence of EDTA and fucoidan.
8  the presence of EDTA and the polysaccharide fucoidan.
9 oidan (Fysk) and those of previously studied fucoidans.
10 chinery for the degradation of six different fucoidans.
11  maximum sulphated fucoidan content (41.38 g fucoidan/100 g extract) was obtained at 160 degrees C, w
12  In particular, administration of 2 doses of fucoidan (25 mg/kg) over 6 hours produces profound mobil
13 gregation and Syk phosphorylation induced by fucoidan, a CLEC-2 agonist, were unaffected in RhoG-defi
14                                              Fucoidan, a known ligand of class A macrophage scavenger
15                                              Fucoidan, a multifunctional marine polymer, is normally
16                                              Fucoidan, a polysaccharidic ligand of the adhesion molec
17                                              Fucoidan, a sulfated polysaccharide found in algae, play
18                                              Fucoidan, a sulfated polysaccharide from Fucus vesiculos
19                            AV513 is a select fucoidan, a sulfated polysaccharide of botanical origin.
20                                   Similarly, fucoidan, a sulfated polysaccharide that binds to L-sele
21                                              Fucoidan accumulated during incubations of F. vesiculosu
22 ulocyte colony-stimulating factor (G-CSF) or fucoidan administration.
23 itive reconstitution experiments reveal that fucoidan also elicits long-term (more than 6 months) rep
24                                              Fucoidan also interferes with leukocyte rolling by bindi
25 s, mainly driven by hydrogen bonding between fucoidan and catechin or phloroglucinol.
26                                 In addition, fucoidan and EDTA abrogate the enhancing effect of HBP o
27 ing structure-dependent interactions between fucoidan and phenolic compounds.
28                   Particular emphasis on the fucoidan and phlorotannin polymeric fractions is given,
29 abundant and highly specialized degraders of fucoidans and other complex polysaccharides.
30 tes such as sulfated Le(x), heparan sulfate, fucoidan, and carrageenan.
31 f soluble glycoconjugates, of which heparin, fucoidan, and dextran sulfate were the most effective.
32 h as different glycosaminoglycans, alginate, fucoidan, and glycans were profiled by this comprehensiv
33 ulfate 500K, dextran sulfate 5K, sulfatides, fucoidan, and heparin but not by chondroitin sulfate A.
34 sigargin and the scavenger receptor A ligand fucoidan, and restoring iPLA(2)betaexpression with recom
35 ies to confirm suggested structures of algal fucoidans, and (iii) developing a fucoidan microarray.
36 at of other polysaccharides, suggesting that fucoidans are more recalcitrant and may sequester carbon
37 e complexity of the pathways underscores why fucoidans are probably recalcitrant and more slowly degr
38 fated polysaccharides from brown algae - the fucoidans - are known to be a topic of numerous studies,
39                          Thus, our data show fucoidan as a novel CLEC-2 receptor agonist that activat
40               Measurements and Main Results: Fucoidan attenuated chronic hypoxia-induced PH in mice,
41 ger receptor inhibitors, dextran sulfate and fucoidan, attenuated monocyte migration toward stressed
42 nd crosslinking methods, then highlights the fucoidan attributes, fabrication of fucoidan-based elect
43 ghts the fucoidan attributes, fabrication of fucoidan-based electrospun nanofibers, their properties
44 ay shows that CLEC18 preferentially binds to fucoidan, beta-glucans, and galactans.
45    This study investigated the multiproduct (fucoidans, beta-glucans, proteins, carotenoids, fatty ac
46 RNA for macrophage scavenger receptor A, and fucoidan blocking of macrophage scavenger receptors inhi
47 sulfated polysaccharides dextran sulfate and fucoidan, but not others, reduce endothelial cell-surfac
48 ture of algae and facilitates the release of fucoidan by hot water extraction.
49             Furthermore, we demonstrate that fucoidan, by itself, stimulates TNF-alpha release from i
50             We find that dextran sulfate and fucoidan can bridge the extracellular domain of NRP1 to
51 l permeability of high molecular weight (Mw) fucoidan can limit its effectiveness in drug action, whi
52                  The sulfated polysaccharide fucoidan can rapidly mobilize hematopoietic progenitor c
53                                              Fucoidan competes for binding with anti-Ly-49A antibodie
54                                    Dissolved fucoidan concentrations in seawater adjacent to algae re
55     In addition, it binds the polysaccharide fucoidan, consistent with its C-type lectin homology and
56  showed that Japanese Cladosiphon okamuranus fucoidan contained 70.13 +/- 0.22 wt% fucose and 15.16 +
57                        The maximum sulphated fucoidan content (41.38 g fucoidan/100 g extract) was ob
58                            Here, we report a fucoidan-decorated silica-carbon nano-onion (FSCNO) hybr
59        The sulfated glycoconjugates heparin, fucoidan, dextran sulfate 5000, and dextran sulfate 500
60 tion on reducing the molecular weight of the fucoidan extracts and examine the cytotoxic effect of di
61                                    The crude fucoidan fractions were tested at 25-500 mug/mL, showed
62 y was to elucidate the chemical structure of fucoidan from Cladosiphon okamuranus harvested in Japan.
63 fic pathways requiring about 100 enzymes per fucoidan from different species of brown algae.
64 an effective method for depolymerizing crude fucoidan from Fucus Vesiculosus seaweed.
65 ry three fucose units, i.e. the structure of fucoidan from Japanese Cladosiphon okamuranus is [->3)-a
66                   However, the extraction of fucoidan from seaweeds often involves the use of harsh c
67               The study aimed to (1) extract fucoidan from the seaweed Fucus vesiculosus (FV) using a
68                In colony formation assay the fucoidans from different species of brown algae showed s
69 vidence for further exploring the use of the fucoidans from S. cichorioides, F. evanescens, and U. pi
70  by chronic hypoxia (35 d) were given either fucoidan (from Fucus vesiculosus) or anti-P-selectin ant
71 ifferent than those of commercial food grade fucoidan (Fysk) and those of previously studied fucoidan
72 arides by (i) characterizing two endo-acting fucoidan glycoside hydrolases (GH107), (ii) utilizing th
73                                              Fucoidan has attracted considerable attention from scien
74                                              Fucoidan has been used to inhibit the binding of various
75                                              Fucoidan, heparin, or dextran sulfate, all of which are
76 cular diversity and structural complexity of fucoidan hinder precise structure-function studies.
77                 Furthermore, the efficacy of fucoidan in hemophilia raises the possibility that decre
78 apidly and dramatically after treatment with fucoidan in monkeys and in mice, coinciding with decreas
79        We report on a role for selectins and fucoidan in progenitor mobilization.
80 c release, and we find that thapsigargin and fucoidan induce mitochondrial phospholipid loss and cyto
81 hibition of elastase activity did not impair fucoidan-induced mobilization.
82 is not required but confers an advantage for fucoidan-induced mobilization.
83                                              Fucoidan-induced platelet activation had a lag phase, wh
84                                              Fucoidan-induced platelet activation was completely abol
85                           On the other hand, fucoidan-induced platelet activation was inhibited in pl
86 ffect on platelets and the receptor by which fucoidan induces cellular processes has not been elucida
87           In this study, we demonstrate that fucoidan induces platelet activation in a concentration-
88                                    In vitro, fucoidan inhibited hypoxia and growth factor-stimulated
89   Sulfated polysaccharides (e.g. heparin and fucoidan) inhibited binding of soluble DC-HIL-Fc and adh
90                   These enzymes depolymerize fucoidan into fucose, which is metabolized in a proteome
91                                 Conclusions: Fucoidan is a potent natural adjuvant that represents a
92                                              Fucoidan is a sulfated polysaccharide isolated from brow
93                                              Fucoidan is a sulphated polysaccharide that consists mai
94                                              Fucoidan is a sulphated polysaccharide, made up mainly o
95          Sulfation is critical as desulfated fucoidan is ineffective.
96   Due to its persistence in the environment, fucoidan is potentially a pathway for marine carbon sequ
97                     Microbial degradation of fucoidans is slower than that of other polysaccharides,
98                  In this study the effect of fucoidans isolated from brown algae Saccharina cichorioi
99 r, carrageenan, porphyran), brown (alginate, fucoidan, laminarin, mannitol), and green (ulvan) seawee
100 lose, chitosan, pectin, starch, carrageenan, fucoidan, mannan, glucomannan, and arabic gum) and prote
101 s of algal fucoidans, and (iii) developing a fucoidan microarray.
102 ns (e.g. fucosylated chondroitin sulfate and fucoidan), nothing is known about their protein-linked g
103 Automated glycan assembly provides access to fucoidan oligosaccharides.
104 e, evidence is provided that the addition of fucoidan or dextran sulfate to unfractionated plasma res
105 t treatment with the sulfated polysaccharide fucoidan or the structurally similar dextran sulfate inc
106 e the therapeutic potential of targeting the fucoidan/P-selectin axis in PH.
107                           The effects of the fucoidan/P-selectin axis on vascular remodeling and pulm
108  Finland to secrete 0.3% of their biomass as fucoidan per day.
109 d by negatively charged molecules, including fucoidan, poly I, and polyvinyl sulfate.
110 l inhibitors of class A scavenger receptors (fucoidan, polyinosinic acid, and dextran sulfate) reveal
111 asis for molecular level investigations into fucoidan's roles in medicine and carbon sequestration.
112 imum estimation by acid hydrolysis indicated fucoidan secretion at a rate of 28 to 40 mg C kg(-1) h(-
113                                     Rates of fucoidan secretion by brown algae remain unknown due to
114 nly of carbon, oxygen, hydrogen, and sulfur, fucoidan secretion does not consume nutrients enabling c
115                        The global utility of fucoidan secretion is an alternative pathway for carbon
116                                    The algal fucoidans specifically and markedly suppressed the proli
117 the antioxidant butylated hydroxytoluene nor fucoidan, suggesting that lipid accumulation did not inv
118 haM-/- HPCs were preferentially mobilized by fucoidan, suggesting that the enhanced mobilization is c
119 he algae sequester more carbon into secreted fucoidan than their biomass.
120 ration of fucose, related to the presence of fucoidans that have important biological functions.
121 trations of a highly charged polysaccharide, fucoidan, the microscale ordering of Fmoc-FRGDF peptide
122 to 1 Gt of biomass annually, yet the fate of fucoidan-their major cell wall polysaccharide-remains po
123 enon we found that BM myeloid cells bound to fucoidan through the integrin alphaMbeta2 (macrophage an
124 and the binding was inhibited by heparin and fucoidan, thus supporting the hypothesis that P97 was ac
125 erpretation of results from studies that use fucoidan to "block" either scavenger receptors or L- or
126                            Administration of fucoidan to mice reduces VEGF(165)-induced angiogenesis
127 ng of acetylated low density lipoprotein and fucoidan to MSR-A in human THP-1 macrophages triggered t
128 kin-8, MCP1, or MMP9 were also present after fucoidan treatment, studies in gene-ablated mice (GCSFR(
129 1 (SDF-1) were achieved in alphaM-/- mice by fucoidan treatment.
130                      Mobilization of HPCs by fucoidan was enhanced in animals deficient in alphaM (al
131                               In this study, fucoidan was extracted from Sargassum binderi (Fsar) fro
132 in FcRgamma-chain null mice, indicating that fucoidan was not acting primarily through GPVI receptor.
133                       Platelet activation by fucoidan was only slightly inhibited in FcRgamma-chain n
134                                          The fucoidan was subject to purification prior to monosaccha
135 um and Saccorhiza polyschides, alginates and fucoidans were the main polysaccharides found.
136 oitin sulfates B and C, heparan sulfate, and fucoidan) were ineffective.
137 utination activity (i.e. dextran sulfate and fucoidan) whereas high concentrations inhibited parasite
138 reated with anti-P-selectin antibody or with fucoidan (which inhibits P- and L-selectin function).
139 x, branched and highly sulfated structure of fucoidans, which also varies among species of brown alga
140                          Dextran sulfate and fucoidan, whose structures are widely divergent from hep
141 that Fsar has fundamental characteristics of fucoidan with different structural conformation i.e. var
142 om, Thalassiosira weissflogii, synthesizes a fucoidan with structural homology to those found in brow
143 ta-glucans, while mAb BAM2 has reactivity to fucoidans with 4-O-sulfate esters.

 
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