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1 or a subset, of the EGF repeats need to be O-fucosylated.
2 orm with higher affinity for heparin was not fucosylated.
3 , acted as efficient glycoligases that could fucosylate a wide variety of complex N-glycopeptides and
4 trast to expectations, PSGL-1 is not heavily fucosylated; a majority of the O-glycans are disialylate
8 Normal plasma IgG contains approximately 94% fucosylated Abs, but alloantibodies against, for example
12 pha2-3 glycans, including alpha2-3GalNAc and fucosylated alpha2-3 glycans (including sialyl Lewis x),
14 n strategy to separate functionally relevant fucosylated and afucosylated glycans on mononclonal anti
15 N-glycans are predominantly biantennary and fucosylated and contain varying levels of alpha2-6-linke
16 results in a form of the protein that is not fucosylated and has substantially weaker activity in cel
17 e tandem mass spectrometry; these are highly fucosylated and have a novel core that contains internal
18 sed 20 monosialylated and nonsialylated, and fucosylated and nonfucosylated complex- and hybrid-type
21 mannosamine (ManNAc), were incorporated into fucosylated and sialylated glycans in several cancer cel
23 taLAZ (P = 0.035), and relative abundance of fucosylated and sialylated HMOs with language at 18 mo (
24 gy that can give a library of differentially fucosylated and sialylated oligosaccharides starting fro
25 samine-type structures were found to be core fucosylated and some of them contained one to three lact
26 ogeneous polysaccharide composed of a highly fucosylated and xylosylated galactose backbone with arab
28 were poorly galactosylated, not processively fucosylated, and negligibly inhibitory, whereas the fuco
35 core structures can be decorated with novel fucosylated antennae composed of Fucalpha(1-3)GlcNAc.
36 on its N-glycans, despite these lacking the fucosylated antennae typical of many other eukaryotes; s
37 nti-CD20 antibodies compared with fully core-fucosylated anti-CD20 antibodies, suggesting the presenc
41 esidues and appear to be more effective than fucosylated antibodies in promoting phagocytosis of anti
43 e form with lower heparin affinity being 97% fucosylated at this position, whereas the form with high
44 en animals given NFb12 and those given fully fucosylated b12, indicating that FcgammaR-mediated activ
49 e Fv region have three characteristics (core-fucosylated biantennary oligosaccharides with one or two
51 after surgery with the decrease of most core-fucosylated biantennary structures, as well as the incre
52 d a larger proportion of sialylated and core-fucosylated biantennary, triantennary and tetra-antennar
53 Fc region contained typical Fc glycans (core-fucosylated, biantennary oligosaccharides with zero to t
55 enrichment of specific antigen responses for fucosylated bisecting glycoforms and the subsequent asso
56 ohydrates including high mannose structures, fucosylated blood group antigens, and glycans with termi
57 BabA adhesin of Helicobacter pylori binds to fucosylated blood group antigens, such as the Lewis(b) a
59 that many proteins in human tissues are core-fucosylated, but their expression is localized to skin k
61 Man5GlcNAc2 glycan could be efficiently core-fucosylated by FUT8 in an appropriate protein/peptide co
62 ary complex-type N-glycan also could be core-fucosylated by FUT8, albeit at much lower efficiency tha
65 ggest that Sfrs proteins are responsible for fucosylated carbohydrate-dependent lung metastasis of ep
66 egulation and function of terminal alpha(1,2)fucosylated carbohydrates in these and other tissues, we
73 eir highly modified glycosaminoglycans (e.g. fucosylated chondroitin sulfate and fucoidan), nothing i
74 zed holothurian glycosaminoglycan (DHG) is a fucosylated chondroitin sulfate with antithrombin-indepe
75 zed holothurian glycosaminoglycan (DHG) is a fucosylated chrondroitin sulfate that possesses antithro
76 a predominance of bi- and tri-antennary core-fucosylated complex type structures carrying one, two, a
80 the expression of sialyl Lewis X and sialyl-fucosylated core 2 O-glycan (CHO-131 antigen), respectiv
85 d on the human receptor CD147/Basigin, while fucosylated derivatives of this N-glycan impaired bacter
88 lycans are of the complex type with the core-fucosylated disialylated biantennary and trisialylated t
89 to be important for the recognition of an O-fucosylated EGF repeat by all three mammalian Fringes.
91 uences that will allow us to predict which O-fucosylated EGF repeats are modified by the Fringes.
92 laboratory have demonstrated that not all O-fucosylated EGF repeats of Notch are further modified by
93 acceptor specificity, since it is unable to fucosylate either Galbeta1-4Glcbeta-R or free lactose an
95 , unexpected mucosal expression of alpha(1,2)fucosylated epitopes in nonsecretor individuals was freq
96 ression of Slc35c2 reduces expression of the fucosylated epitopes Lewis X and sialylated Lewis X in C
97 hat BambL could recognize a wide spectrum of fucosylated epitopes, albeit with a lower affinity for b
101 N-glycans and milk oligosaccharides based on fucosylated fragment ions with characteristic CCSs.
102 pha1,6-fucosyltransferase (FUT8) to directly fucosylate full-size mature N-glycans in a chemoenzymati
105 on constants (Kd) for the nonfucosylated and fucosylated FVII EGF-1 were found to be 16.4 +/- 1.8 and
106 toward a variety of sulfated, sialylated, or fucosylated Gal beta 1,3/4GlcNAc beta- or Gal beta 1,3Ga
107 discerned with sulfated, sialylated, and/or fucosylated Gal beta 1,3/4GlcNAc beta-based acceptor moi
108 rum albumin coupled with a common glycoform (fucosylated glycan lacking the alpha1,3-linked mannose)
110 for investigations into the role of specific fucosylated glycan motifs of schistosomes in parasite-ho
111 one or more alpha2,3-sialylated and alpha1,3-fucosylated glycan receptors that are unique from those
112 teract with alpha2,3-sialylated and alpha1,3-fucosylated glycan receptors, including 6-sulfo-sialyl L
113 od fluke Schistosoma mansoni produces highly fucosylated glycan structures on glycoproteins and glyco
115 orders was shown for twins with low level of fucosylated glycans and high level of non-fucosylated gl
116 that neither the FUT loci nor their cognate fucosylated glycans are essential to normal development.
124 etailed structures and roles of other highly fucosylated glycans that co-exist in the parotid gland a
126 y that selectins and DC-SIGN bind to related fucosylated glycans, but the mechanism of the interactio
127 orhabditis elegans expresses a wide range of fucosylated glycans, including N-linked oligosaccharides
128 attack the human glycome, how it copes with fucosylated glycans, which are primarily histo-blood gro
136 as well as asymmetrically and symmetrically fucosylated, glycans were identified from HCCF in experi
137 m-free NMRI mice revealed that production of fucosylated glycoconjugates and an alpha1, 2-fucosyltran
139 ging but highly desirable; resolution of the fucosylated glycoforms is of particular interest due to
140 resented as relative abundance of individual fucosylated glycoforms normalized to the level of their
141 f the outer arm and total fucosylation of 12 fucosylated glycoforms of 9 glycopeptides in 7 plasma pr
142 line results in the production of fully core-fucosylated glycoforms of the oligomannose substrate Man
144 utant animals are defective in production of fucosylated glycolipids and that bre-1 mutant animals ma
147 n leukocyte CD11b/CD18 and basally expressed fucosylated glycoproteins followed by binding to desmoso
149 synthesis of structurally well-defined, core-fucosylated glycoproteins remains a challenging task due
152 ted GSLs (e.g., Gb3Cer/Gb4Cer precursors and fucosylated GSLs) in tissue biopsies from three CRC pati
154 th the defucosylated pentasaccharide and the fucosylated hexasaccharide without a significant differe
156 The capability to preferentially consume fucosylated HMO suggests a competitive advantage for the
158 l gene cluster devoted to the utilization of fucosylated HMO, including genes for import of fucosylat
161 for general categories of HMOs (total HMOs, fucosylated HMOs, and sialylated HMOs), 51 individual HM
163 e fecal microbiota of Fut2(-) mice that lack fucosylated host glycans show decreased alpha diversity
164 wing intravascular administration into mice, fucosylated human CAR-T cells infiltrate marrow with 10-
165 Fucosyllactose (2'-FL), a major component of fucosylated human milk oligosaccharides, is beneficial t
167 d galactosylation, decreased sialylation (of fucosylated IgG glycan structures) and increased bisecti
168 glycoforms, in which more than 50% were core-fucosylated, implicating a clear GnT I-independent core
169 prepared from transgenic lines were able to fucosylate, in vitro, purified AGPs from BY2 wild type c
170 al for OGT activity, and 3) its ability to O-fucosylate itself and a model substrate and to specifica
171 e domain probes expressed nearly exclusively fucosylated LacdiNAc on bi-antennary complex-type chains
172 produce complex-type N-glycans with alpha1,3-fucosylated LDN (LDNF) GalNAcbeta1-4(Fucalpha1-3)GlcNAcb
174 nts can be difficult, in particular terminal fucosylated Lewis and blood group antigens present on N-
175 an outer membrane protein that binds to the fucosylated Lewis b histo-blood group antigen on the sur
176 of human adenocarcinomas express sialylated, fucosylated Lewis blood group antigens on cell surface a
177 lly, that simultaneous DC-SIGN engagement by fucosylated ligands and TLR4 signaling was required for
178 participates in the generation of alpha(1,3)fucosylated ligands for L-selectin and provide further e
182 ll surface oligosaccharides contain specific fucosylated moieties expressed in lineage- and/or tempor
184 1) and the alpha2,3-sialylated- and alpha1,3-fucosylated-moiety sialyl-Lewis x (sLe(x)), which modifi
185 a closely related sialylated and alpha-(1,3) fucosylated molecule, plays a key role in HGE infection,
186 ulations, confirmed by experiment, predicted fucosylated molecules that are restricted to librations
187 cosylated HMO, including genes for import of fucosylated molecules, fucose metabolism and two alpha-f
188 7 was conjugated to anti-mesothelin and anti-fucosylated monosialotetrahexosylganglioside (FucGM1) an
189 ter pylori, abnormal expression of alpha(1,2)fucosylated motifs and binding of GII.4 virus-like parti
190 ards a subset of glycans containing multiple-fucosylated motifs remained high until 6 weeks post-chal
192 al alterations include an increase in large, fucosylated, mucin-type glycoproteins, changes in the ty
193 udies indicate that expression of sialylated fucosylated mucins by human carcinomas portends a poor p
194 ant animals, although viable, show a lack of fucosylated N- and O-glycans, based on mass spectrometri
195 the glycosylation reveals that only a single fucosylated N-acetyl glucosamine on N54 is required for
198 ine (PHN) labeling for structural studies of fucosylated N-glycans by tandem MALDI mass spectrometry
200 e possible functional significance of highly fucosylated N-glycans is discussed in relation to their
201 d for selective capture and analysis of core fucosylated N-glycans present in complex glycan mixtures
202 rocainamide + H](+) in the tandem MS data of fucosylated N-glycans rapidly verifies core fucosylation
203 Asn623 and Asn752) are occupied with highly fucosylated N-glycans that possess unusual difucosylated
204 healthy human myelin, MOG is decorated with fucosylated N-glycans that support recognition by the C-
205 selective and quantitative profiling of core fucosylated N-glycans using UPLC-HILIC-FLR analysis was
206 which a 55% increase of alpha-2,6-sialylated fucosylated N-glycans was revealed, demonstrating the gr
207 strated its ability to bind to core alpha1-6 fucosylated N-glycans, but not to core alpha1-3 fucosyla
208 osylated N-glycans, but not to core alpha1-3 fucosylated N-glycans, or other alpha1-2, alpha1-3 and a
209 venue to a wide variety of homogeneous, core-fucosylated N-glycopeptides and N-glycoproteins that are
213 teracting specifically with high mannose and fucosylated neutral carbohydrate structures, langerin ha
214 solated a nonfucosylated and three variously fucosylated neutral oligosaccharides from human milk tha
216 ults demonstrate that PSGL-1 contains unique fucosylated O-glycans that are predicted to be critical
219 , agalacto, bisected biantennary, and a core-fucosylated oligosaccharide in the position of Asn B37 w
220 glycan moiety consisting of a sialylated and fucosylated oligosaccharide properly positioned on a cor
224 gests that the N-CRD recognizes more complex fucosylated oligosaccharides and with a relatively highe
225 -dimensional structure and dynamics of three fucosylated oligosaccharides are investigated using a co
227 combinant Sfrs1 protein bound to a series of fucosylated oligosaccharides in glycan array and plate-b
232 are the ancestral state in angiosperms, with fucosylated oligosaccharides transported across the plas
233 ed recombinantly and demonstrated to bind to fucosylated oligosaccharides with a preference for alpha
238 fetal bovine serum acetylcholinesterase were fucosylated on the innermost N-acetylglucosamine residue
239 data suggest that murine myeloid leukocytes fucosylate only a few specific glycans, which interact p
240 y oligosaccharides including structures with fucosylated or sialylated N, N'-diacetyllactosediamine (
242 appear to be caused by structural changes in fucosylated pectic components such as rhamnogalacturonan
243 hese analyses showed the presence of various fucosylated, phosphorylated, sialylated, and multiply su
244 d neutrophils, and a cell line devoid of the fucosylated platelet selectin glycoprotein ligand 1 (PSG
248 oying CD11b/CD18 as a probe to blot T84 cell fucosylated proteins purified via fucose-specific lectin
249 he characteristic punctate localization of O-fucosylated proteins suggest that TgSPY controls the lev
250 on encodes an adhesin that binds an alpha1-2 fucosylated receptor(s) present in the cecal mucosa.
255 to express alpha2-3-sialylated and alpha1-3-fucosylated selectin ligands such as sialyl Lewis x (sLe
256 ed can allow rapid identification of various fucosylated, sialylated, sulfated glycotopes and definit
260 idase digestions, and co-chromatography with fucosylated standards, the product of the reaction with
261 ed nonfucosylated seed amyloid xyloglucan or fucosylated stem xyloglucan as a substrate with equal fa
262 glycans might be complicated by the partial fucosylated structure and the alpha-Gal (1-3)-beta-Gal o
268 mplying that as yet unidentified sialylated, fucosylated structures serve as physiologically relevant
269 es (10-15%) of extended SLex with internally fucosylated structures: NeuAc alpha 2-->3 Gal beta 1-->4
270 mprise a large enzyme family that recognizes fucosylated substrates with diverse alpha-linkages on th
273 somers, and regioisomers of afucosylated and fucosylated sulfoglycans containing sulfated-6-GlcNAc an
275 H-type alpha1,2FT does not indiscriminately fucosylate terminal galactosyl residues in complex-type
276 nd similarly to alpha3-sialylated and alpha2-fucosylated terminal LN, but not to alpha6-sialylated an
279 studies have suggested that the sialylated, fucosylated tetrasaccharide sialyl Lewis X (sLex) is an
281 A minority of the O-glycans are alpha-1,3-fucosylated that occur as two major species containing t
282 clinical data suggesting that use of ex vivo fucosylated third-party human regulatory T cells (Tregs)
285 The DG9-glycan index, which is the ratio of fucosylated to nonfucosylated triantennary glycans, prov
286 he untreated Tregs, the murine recipients of fucosylated Tregs maintained weight, had ameliorated cli
293 ures, sometimes methylated and core alpha1,6-fucosylated, with terminal beta1,3-linked galactose; a r
295 ble genotypes all had substantial amounts of fucosylated XyGs and weakly ME-HGs, but lacked heavily M
296 s of PD-resistant grapevine genotypes lacked fucosylated XyGs and weakly methyl-esterified HGs (ME-HG
297 upport the conclusion that weakly ME-HGs and fucosylated XyGs are substrates of the pathogen's CWDEs
299 tain less than 2% of the wild-type amount of fucosylated xyloglucan because of a point mutation in th